PRELPFBLN5ABCA8CHRDL1NEDD9SORBS1TNS1HBBTSPAN4CYBRD1SDPRFIGFADH1BANGPT1PRG4LEFTY2FCER1ACD1CFLJ13197MAPK10ARHGAP24DMDSSBP2NPR1RRADADRB2CBX7ITGA9RBMS3FAT4GPRASP1KCNQ1MECOMPLA2G10ALDH3A1TBC1D2KCND3BTG2CYFIP2CHI3L2CLUTSPAN7GPX3C4BPAPIGRSLC22A3ACSM3RNASE4CATMOSC2ETS2CRIM1PRSS12SLPITLR5CD44CIITATLR2�������MMP28CAPN3ROS1SLC39A8ST3GAL6ETV1AQP4TNNC1ACADLDUOX1CLDN18SERPIND1PID1SCARF1LRRC36RASGRF1PVRL3PHACTR1CEACAM8LEPREL1HLFCPB2PLA2G1BTOXFGF9MST1P9MST1ZBTB20DAPK1PIONSLC16A7COL4A3COL4A4FBXO9SHANK2PEX11AALDH5A1ZNF204PCDK10AMTLONP2ABCC6ECHDC2PTCH1ACACBCTNNBIP1CTDSPLPLLPSNX1VPS13DPDE4DIPPNPLA4ATXN10COX16SRIKANK1HSDL2VPS13ASPAG9RUFY3EIF4BGSTA4MTRRN4BP2L2ARAP2SRSF11SFRS18MED6NUPL1MTUS1PNMA2RBPMSIKBKBKBTBD11TNFRSF10CIVDMYO5CRAB27ACD55LMO7SLC16A5ZNF750PON3CDS1MAP3K13TMEM180HOOK2S100A14PRKAB1UNC13BPMM1ST7ABHD14ASCNN1BPLXNA2ENTPD3FOXA2RAP1GAPHNF1BPRR15LACSL5AQP3FMO5PLCH1TPD52L1MOSC1ADCK3LOC100506517ALDH6A1ALDH3A2EPHX1MEGF9PPP2R5AFAM184AGPD1LC1orf116GPR116C4orf31NR3C2CEBPAADCY9HSD17B6C7orf23CTSHRNASE1IL6RCYP4B1SELENBP1FOLR1CYP2B7P1MALLSLC47A1NINJ2ICAM4APOHGLS2GGTLC1GGT1GLSDPP4SFTPCLAMP3ABCA3SFTPDCACNA2D2SFTPBCISHAK1FBP1MID1IP1NRGNCEBPDCITED2ATP8A1CD302LIMCH1CYB5AHOPXLMO3PARM1AHCYL2ATP11AWIF1PGCTACC2DLC1RHOBTB2NEDD4LMAOATACC3LMNB2PTTG1LMNB1MCM4FEN1MCM2TK1KPNA2TRIP13CDCA8HJURPUBE2CFOXM1KIF2CCDC20BIRC5KIF4ATPX2CCNB1KIF20ADLGAP5CDKN3CENPABUB1TOP2AKIF14NEK2ASPMCENPFMLF1IPMCM6DTLCENPNTYMSRRM2MELKMAD2L1CEP55KIF11ZWINTCDK1RAD51AP1RACGAP1CCNB2KIAA0101PBKFANCINUSAP1BUB1BPRC1GTSE1GINS1MYBL2KIF18BCDC6SHCBP1ORC6RAD51NCAPHFAM64AHMMRMKI67MCM10CHEK1CCNA2KIF23NDC80TTKNCAPGWDHD1E2F8STILDONSONC21orf45RPL39LCTSL2CCNE1GGHECT2CKAP2DBF4EZH2NCAPG2DSCC1CCNE2ATAD2BOP1SLC7A5SHMT2LOC100507192SLC7A1HMGA1UCK2MTHFD2EIF4EBP1PLA2G4ACHL1TSKUGCLCBASP1S100POR7E37PMAP4K2QPRTFADS1MLLT11UCHL1PFN2PHGDHMARK1TUBB3DUSP14LEPREL4TMEM132AKIF3CEHD3PSME4MARCKSL1E2F3PAFAH1B3SOX4PSPHNUPL2TBRG4NUDT1YKT6MPP6HUS1BZW2IMPAD1NRASTMEM48CALUKPNA1FGFR1OPDHFRPHTF2IGF2BP3KLHL7RALAITCHAPOBEC3BIFRD1GPSM2PPAP2CPKP3ST14KRT8DSC2PERPHN1CTTNACOT7MAD1L1SLC6A8IRAK1GALNT2GPIMRPS12ALDOCSTC1EGLN3PLOD2AK4PFKPSLC2A1SLC16A3HS2ST1SSX2IPB3GALNT1SNX7VANGL1ELOVL6SLC16A1PCDH7SEMA3AWASF1TMEFF1SYNJ2TPBGF5TCN1B3GNT3SLCO4A1HOXA1HOXA10GCNT1BIDC14orf143CLMNNUP62CLPAQR4CARHSP1PMAIP1MMDIL8SERPINE1FOSL2MMP1PDLIM5TPM4SPP1PLAURIL1RNMYO5ADFNA5OSBPL3SKAP2FSCN1TUBB6DNM1ACTN1BMP1CDH3SERPINH1GPC1AHNAK2LAMC2PDLIM4TGFBIPLAUSRPX2UPP1SLC20A1GRB10CREB5SPAG4PDK1ITM2CATP2A3SEC14L1DENND5BADAADAMDEC1GZMBMMP12SLC2A5EMR2RARRES1LXNPLTPRBP1ASAP1VOPP1MARCKSEYA2SLC2A10VTCN1MMP7GALNT6GALNT14CPDKDRCXCL6MUC16SPAG1SLC12A2SYT1TUBB2BTUBB2ADNAJC12QPCTSCG5PCP4SLC1A4PTP4A3HOXC6HOXC4SKAP1HOXB2HOXB7SLAMF7IGHDIG����IG� �1IGHMIG���5IGLV2��IGKCIGLJ3IGL@IGLV3���LOC91316IGLL3PCD79AIGLV1� �MGC29506FAM198BPRSS23TWSG1FKBP14TRPS1NPTX2PGFHTR2BDOK5MN1LRRC17ODZ4C1QTNF3GPR4COL4A1MCAMDBN1COL18A1NOTCH3COL6A2COL6A1CD248PCOLCEEMILIN1SNAI2OLFML2BNID2COL15A1GAS1KDELC1CHN1SPON2DPYSL3PXDNXYLT1TIMP3RCN3COPZ2MFAP2SERPINF1POSTNCOL5A2COL3A1COL1A2GREM1FAPSULF1VCANINHBACOL1A1THY1MXRA5THBS2COL5A1CILPCOL11A1LRRC15MMP11SPOCK1MFAP5ADAMTS5CXCR7VEGFCLOXANGPTL2TWIST1LOXL2TNFAIP6TMEM158SPHK1GFPT2ITGA5SERPINE2MMP9VCAM1PDPNTDO2FMO1CCL11WT1SLC12A8TNFSF4ADAM12WISP1

EGFRwt/KRASwtKRAS-mutatedEGFR-mutated

Data setEGFR-1/2 group

EGFR-1

EGFR-2

GSE31210

Chitale U133A

Chitale U133 2plus

E-MTAB-923

GSE13213

Shedden

GSE3141

GSE42127

EGFR-groups

Data sets

A)