a tick mannose-binding lectin inhibitor interferes with the vertebrate complement cascade to enhance...

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A Tick Mannose-Binding Lectin Inhibitor Interferes with the Vertebrate Complement Cascade to Enhance Transmission of the Lyme Disease Agent Tim J. Schuijt, Jeroen Coumou, Sukanya Narasimhan, Jianfeng Dai, Kathleen DePonte, Diana Wouters, Mieke Brouwer, Anneke Oei, Joris J.T.H. Roelofs, Alje P. van Dam, Tom van der Poll, Cornelis van't Veer, Joppe W. Hovius, Erol Fikrig Cell Host & Microbe Volume 10, Issue 2, Pages 136-146 (August 2011) DOI: 10.1016/j.chom.2011.06.010 Copyright © 2011 Elsevier Inc. Terms and Conditions

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Page 1: A Tick Mannose-Binding Lectin Inhibitor Interferes with the Vertebrate Complement Cascade to Enhance Transmission of the Lyme Disease Agent Tim J. Schuijt,

A Tick Mannose-Binding Lectin Inhibitor Interferes with the Vertebrate Complement Cascade to Enhance Transmission of the Lyme Disease Agent 

Tim J. Schuijt, Jeroen Coumou, Sukanya Narasimhan, Jianfeng Dai, Kathleen DePonte, Diana Wouters, Mieke Brouwer, Anneke Oei, Joris J.T.H. Roelofs, Alje P. van Dam, Tom van der Poll, Cornelis van't Veer, Joppe W. Hovius, Erol Fikrig  

Cell Host & Microbe Volume 10, Issue 2, Pages 136-146 (August 2011)

DOI: 10.1016/j.chom.2011.06.010

Copyright © 2011 Elsevier Inc. Terms and Conditions

Page 2: A Tick Mannose-Binding Lectin Inhibitor Interferes with the Vertebrate Complement Cascade to Enhance Transmission of the Lyme Disease Agent Tim J. Schuijt,

Figure 1

Cell Host & Microbe 2011 10, 136-146DOI: (10.1016/j.chom.2011.06.010) Copyright © 2011 Elsevier Inc. Terms and Conditions

Page 3: A Tick Mannose-Binding Lectin Inhibitor Interferes with the Vertebrate Complement Cascade to Enhance Transmission of the Lyme Disease Agent Tim J. Schuijt,

Figure 2

Cell Host & Microbe 2011 10, 136-146DOI: (10.1016/j.chom.2011.06.010) Copyright © 2011 Elsevier Inc. Terms and Conditions

Page 4: A Tick Mannose-Binding Lectin Inhibitor Interferes with the Vertebrate Complement Cascade to Enhance Transmission of the Lyme Disease Agent Tim J. Schuijt,

Figure 3

Cell Host & Microbe 2011 10, 136-146DOI: (10.1016/j.chom.2011.06.010) Copyright © 2011 Elsevier Inc. Terms and Conditions

Page 5: A Tick Mannose-Binding Lectin Inhibitor Interferes with the Vertebrate Complement Cascade to Enhance Transmission of the Lyme Disease Agent Tim J. Schuijt,

Figure 4

Cell Host & Microbe 2011 10, 136-146DOI: (10.1016/j.chom.2011.06.010) Copyright © 2011 Elsevier Inc. Terms and Conditions

Page 6: A Tick Mannose-Binding Lectin Inhibitor Interferes with the Vertebrate Complement Cascade to Enhance Transmission of the Lyme Disease Agent Tim J. Schuijt,

Figure 5

Cell Host & Microbe 2011 10, 136-146DOI: (10.1016/j.chom.2011.06.010) Copyright © 2011 Elsevier Inc. Terms and Conditions

Page 7: A Tick Mannose-Binding Lectin Inhibitor Interferes with the Vertebrate Complement Cascade to Enhance Transmission of the Lyme Disease Agent Tim J. Schuijt,

Figure 6

Cell Host & Microbe 2011 10, 136-146DOI: (10.1016/j.chom.2011.06.010) Copyright © 2011 Elsevier Inc. Terms and Conditions

Page 8: A Tick Mannose-Binding Lectin Inhibitor Interferes with the Vertebrate Complement Cascade to Enhance Transmission of the Lyme Disease Agent Tim J. Schuijt,

Cell Host & Microbe 2011 10, 136-146DOI: (10.1016/j.chom.2011.06.010) Copyright © 2011 Elsevier Inc. Terms and Conditions