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A4 Cancer Card 29/3/07 12:04 Page 1

Cancer antibodies from Abcam: See more cancer products at: www.abcam.com/cancer

Product Clonality Applications Host Species DatasheetReactivity www.abcam.com/ab…

Product Clonality Applications Host Species DatasheetReactivity www.abcam.com/ab…

A RAF P WB Rb Hu, Mm, R 19880AKT P IHC-Fr, IP, WB Rb Hu, Mm, Rt, C 18785AKT P ELISA, IHC-P, WB Rt Mm, Rt, Hu 47432AKT P ELISA, IHC-P, WB Rb Mm, Rt, Hu 47610AKT (Phospho S473) P ELISA, IHC-P Rt Hu, Mm 28821AKT (phospho T308) P ELISA, IHC-P, WB - Mm, Rt, Hu 38849Bad P ELISA, IHC-P, WB Rb Hu, Mm 28840Bad P ELISA, IHC-P, WB Rb Hu, Mm, Rt 31310Bad (phospho S128) P WB Rb Hu 5687Bad [Y208] M Flow Cyt, ICC/IF, IHC-P, IP, WB Rb Mm, Rt, Hu 32445Bcl2 (phospho S70) P ELISA, IHC-P, IP Rb Hu 28819Bcl2 P IHC-P, IP, WB Rb Hu, Rt, Mm 7973Bcl2 P ICC/IF, WB Rb Hu, Mm, Rt, D 18210c Abl P WB, IHC-P, IP Rb Hu, Mm 15130c-Fos P IHC-P, IHC-PFA, IP, WB Rb Hu, Mm, Rt 7963c-Fos (phospho T325) P WB Rb Hu Mm , Rt 27793c-Fos [2G9C3] M ICC, WB Mm Hu Mm , Rt 16902c-Jun P ELISA, IHC-P, IP, WB Rb Hu, Mm, Rt 31417c-Jun P ICC/IF, IHC-Fr, IP, WB Rb Hu, Rt, Mm 7964c-Jun (phospho 73) [E107} M Dot, Flow Cyt, ICC/IF, IHC-P, IP, WB Rb Mm, Hu 32447c-Jun [EP693Y] M ICC/IF, IHC-P, IP, WB Rb Hu 40766c-Kit (phospho Y703) P ICC, WB Rb Hu, Mm, Rt C, Ch, D 5631c-Kit P Flow Cyt, ICC/IF, IHC-P Rb Hu, Mm 16832c-Kit P IHC-P Rb Hu 956c-Kit [Y145] M IHC-P, WB Rb Hu. 32363c-Myc P ELISA, IHC-P, WB Rb Mm, Rt, Hu 39686c-Myc P ELISA, IHC-P, WB Rb Mm, Rt, Hu 39688c-Myc (phospho T58) P ELISA, IHC-P, IP, WB Rb Hu, Mm 28842c-Myc [9E11] ChIP grade M ChIP, IHC-Fr, IHC-P, IP, WB Mm Hu, Mm, ch 56c-Myc [Y69] M ICC/IF, IHC-P, IP, WB Rb Hu 32072EGFR P IHC-Fr, IHC-P, IP, WB Rb Hu, Mm, Rt, Dg 2430EGFR P ELISA, ICC, ICC/IF, IF, IHC-Fo, IP, WB Sh Hu, Mm, Rt, Ch 30524EGFR M Flow Cyt, IHC-Fr, IP, WB - Rt 231EGFR (phospho Y1068) P WB Rb Hu, Rt 5644EGFR [F4] M AF, ELISA, IHC-Fr, IHC-P, IP, RIA Mm Hu 62ERK1 M Flow Cyt, ICC, IHC-P, IP, WB Rb Hu, Mm 32537ERK1 +ERK2 (phospho T185 + T202) P WB Rb Hu 4819ERK2 P IF, IHC-FrFl, IHC-P, IP, WB Rb Hu, Mm, Rt 7948

JNK1 P WB Rb Hu, Mm, Rt 10664JNK1 P EMSA, IHC-Fr, IP, WB Rb Hu, Mm, Rt 7974JNK1+JNK2 (phospho T183+Y185) P IHC-Fr, WB Rb Hu, Mm 4821JNKi+JNK2 [279Q38] M WB Mm Hu, Mm, Rt 37228MDM2 P ELISA, IHC-P, WB Rb Mm, Hu 38618MDM2 P ELISA, IHC-P, WB Rb Mm, Hu 38619MDM2 [2A10] M ICC, IHC-Fr, IHC-P, IP, WB Mm Hu 16895MMP9 P ELISA, IHC-Fr, IHC-P, IP, WB Rb Mm, Hu 38898MMP9 P IHC-Fr, IP, WB Rb Rt 7299p53 M ELISA, Flow Cyt, ICC/IF, IHC-Fr,

IHC-P, IP, WB Mm Hu 1101p53 P WB Rb Hu 2433p53 (phospho S15) P IHC-P, IP, WB Rb Hu, Mm, Rt 1431p53 [BP53-12] M ELISA, ICC, IHC-P, IHC-Fr, IP, WB Mm Mk 7757p53 [Pab 240] M ELISA, Flow Cyt, ICC, IHC-Fr, IHC-P, IP, WB Mm Hu, Mm, Rt 26PI3K p85 alpha [ep380y] M Flow Cyt, ICC/IF, IHC-P, IP, WB Rb Rt, Hu 40755PTEN (phospho S370) P ELISA, IHC-P, WB Rb Hu, Mm, Rt 30654PTEN (phospho S380 + T382 + T383) P ELISA, IHC-P, WB Rb Mm, Rt, Hu 38507PTEN P IHC-Fr, IHC-P, WB Rb Hu, Mm, Rt 23694PTEN P ELISA, IHC-P, WB Rb Hu, Mm, Rt 31392PTEN [4E7] M ELISA, IP, WB Mm Hu 21512PTEN [Y184] M Flow Cyt, ICC, IHC-P, IP, WB Rb Mm, Rt, Hu 32199cH Ras [Y132] M ICC/IF, IP, WB Rb Mm, Rt, Hu 32417cK Ras [234-4.2] M IHC-Fr, IHC-P, IP, WB Mm Hu, Mm, Rt 16819MRas P WB Rb Hu, Mm, Rt 26303N ras + c Ha ras P WB Sh Hu 24043p21 Ras [234-4.2] M IHC-Fr, IHC-P, IP, WB Mm Hu, Mm, Rt, X, C, Ce 16795p21 Ras [F132-62] M ICC, IHC-Fr, IHC-P, IP, WB Mm Hu, Mm, Rt 16907p21 Ras [NCC-RAS-001] M IHC-Fo, IHC-Fr, IHC-P Mm Hu 8752p21 Ras [Y131] M ICC/IF, WB Rb Hu, Does not react with Mm or Rt 32442Ras, prediluted P IHC-P - Hu, Mm, Rt, C 27446vH RAS [Y13-238] M IF, IP Rt Hu,Mm, Rt 13055vH RAS [Y13-259] M ICC, IHC-Fr, IHC-P, IP, WB Rt Hu, Mm, Rt 16881RhoA (phospho S188) P ELISA, WB Rb Hu, Mm, Rt 41435RhoA P ICC, WB Ch Hu 23687VEGF M ELISA, ICC, IHC-Fr, IHC-P, IP, WB Mm Hu, Mm, Rt, D 1316VEGF P IHC-P, WB Ch Hu, Mm, Rt 14078VEGF [5C3.F8] M IHC-P, WB Mm Hu, Mm 3109VEGF [VG76e] M ELISA, IHC-P, WB Mm Hu, C, Pi 119

Aurora A antibody (ab12875)

Clonality Applications Host Species cross reactivityP ICC, IF, IHC-P, WB Rb Hu

Aurora A plays a role in cell cycle regulation during anaphase and/ortelophase in relation to the function of the centrosome/spindle poleregion during chromosome segregation. Aurora A plays a key role duringtumor development and progression and is overexpressed in manyhuman cancers including breast, ovarian and colorectal. Aurora A isviewed as a potential target for anticancer drug treatment.

Survivin antibody (ab8228)

Clonality Applications Host Species cross reactivityP ICC/IF, WB Rb Hu, Mm

Survivin is an inhibitor of apoptosis (IAP), expressed in the G2/M cell cycle phase. At theonset of mitosis, survivin associates with microtubules of the mitotic spindle in a specific andsaturable reaction that is regulated by microtubule dynamics. Disruption of survivin-microtubule interactions results in loss of survivin's anti-apoptotic function and increasedcaspase 3 activity. Survivin is over expressed in a range of tumors including lung, pancreas,breast, prostate and squamous cell carcinoma.

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