aeromedical concerns with the diabetic patient presentation

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    AeromedicalConcerns for the

    diabetic patientTC4 AVMX 721

    Sundaresan Maiyalagan

    15thMay 2012

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    Content Overview

    Introduction

    Current definition and classification of Diabetes

    Complications and its implications foraeromedical transfer

    Aeromedical concerns with management ofblood glucose levels

    General advice for passengers flying with

    diabetes

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    Introduction

    171 million people in the world with diabetes mellitus(DM) in the year 2000 and this is projected to increase to366 million by 2030

    8.3 percent of the U.S. Population

    In Mauritius the prevalence is as high as 15% (2004survey)

    Multiple associated complications and co-morbidities

    Heterogeneous population with a varied range ofdisease spectrum

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    Current definition and classification

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    Current definition and classification

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    Complications and its Implications forAeromedical Transfer

    Acute consequences of impaired glycemic control Hypoglycemia, Ketoacidosis and hyperosmloar non-ketotichyperglycaemic coma

    Stiff Joint Syndrome and associate difficult laryngoscopy

    Cardiovascular complications - Silent MI, Cardiomyopathy

    Diabetic Sensory and Autonomic Neuropathy

    Diabetic Retinopathy and Cerebral Complications

    Diabetic Nephropathy

    Impaired wound healing and immunity

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    Complications and its Implications forAeromedical Transfer

    Diabetic Autonomic Neuropathy effect on various organsCardiovascularResting tachycardiaExercise intoleranceOrthostatic hypotension

    Silent myocardial ischemia

    GIEsophageal dysmotility

    Gastroparesis diabeticorumConstipationDiarrheaFecal incontinence

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    Complications and its Implications forAeromedical Transfer

    Diabetic Autonomic Neuropathy effect on various organs

    GenitourinaryNeurogenic bladder (diabetic cystopathy)

    MetabolicHypoglycemia unawarenessHypoglycemia-associated autonomic failure

    SudomotorAnhidrosisHeat intoleranceGustatory sweatingDry skin

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    Complications and its Implications forAeromedical Transfer

    Diabetic Autonomic Neuropathy effect on various organs

    PupillaryPupillomotor function impairment (e.g., decreased diameter ofdark adapted pupil)

    Argyll-Robertson pupil like phenomenon

    RespiratoryImpaired response to hypoxia and hypercapnia

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    Aeromedical Concerns With ManagementOf Blood Glucose Levels

    Oral Hypoglycaemic Drugs and Insulinadministration

    Blood Glucose monitoring

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    Aeromedical Concerns With ManagementOf Blood Glucose Levels

    Oral Hypoglycaemic Drugs and InsulinadministrationTiming

    Maintaining bioactivity of insulinInsulin pumps and aeromedical transfer

    Picture of the Minimed Paradigm 722 (Insulin pump device,

    Medtronic)(A), with the continuous blood glucose monitor(C) and transmitter (D), and the infusion set (B).

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    Aeromedical Concerns With ManagementOf Blood Glucose Levels

    Oral Hypoglycaemic Drugs and InsulinadministrationTiming

    Maintaining bioactivity of insulinInsulin pumps and aeromedical transfer

    (Bruce R King et al . Diabetes Care 34: 1932-33, 2011

    The cartridge should only contain 1.5 ml of insulin

    Disconnect the pump before takeoff At cruising altitude, take the cartridge out of the pump and remove air

    bubbles before connecting After the plane lands, disconnect the pump and prime the line with 2

    units. Then reconnect the pump.

    During flight emergencies involving cabin decompression, disconnectinsulin pump.

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    Aeromedical Concerns With ManagementOf Blood Glucose Levels

    Blood Glucose monitoring

    Availability

    Variability

    Effect of altitude on glucometer performancePatricia L Brubaker. Adventure Travel and Type 1 Diabetes. Diabetes CARE 2005; 28 (10): 2563-72

    Aircraft regulations regarding use of ContinuousGlucose Monitoring devices

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    General advice for passengers flying withdiabetes

    Two blood glucose monitoring devices, with extrabatteries, packed in separate bags

    Enough insulin, syringes, lancets, and test strips to lastthe entire trip

    For pump users, enough pump supplies for the entiretrip, extra batteries, and supplies of long-acting insulin(ultralente or glargine) and regular or rapid-acting insulinanalog (lispro or aspart) and syringes for use in case of

    pump malfunction or battery failure

    Prescription medicines (including a glucagon emergencykit), for diabetes and other medical conditions

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    General advice for passengers flying withdiabetes

    Simple carbohydrate sources, such as glucose tablets,gels, candy, and nondietetic soft drinks to relievesymptoms of hypoglycemia

    Complex carbohydrate sources, such as breakfast bars,cheese crackers, granola bars, and trail mix to serve assnacks when meals are missed or delayed

    Regular insulin or short-acting insulin analogs fortreating high blood glucose and for sick-day

    management even if these are not part of the patientsregular regimen

    Identification (diabetes identification card, Medic Alertnecklace or bracelet)

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    General advice for passengers flying withdiabetes

    Insurance papers (Confirm before travel what medicalcoverage is available from the insurer in the event of amedical problem abroad.)

    Medications for vomiting and diarrhea

    A first aid kit, including analgesics, antibiotic andantifungal creams, bandages, sterile gauze, andadhesive tape

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    Conclusion

    In conclusion, patients with DM are a heterogeneous

    population, but there are key areas where the aeromedical

    team must focus and be prepared with regards to type of

    diabetes, the associated complications, management of

    blood sugar levels and the effects of aeromedical transfer

    on these areas in order to ensure a safe and effectiveaeromedical transfer of patients with diabetes.

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    Thank YouTC4 AVMX 721

    Sundaresan Maiyalagan

    15thMay 2012