1

Allergy and Hypersensitivity

K. J. Goodrum2005

2

3

Fig.12.6

Early IL-4 response promotes Th2 development that drives B cell class switching to IgE

Fig.12.7

Secreted IgE “sensitizes” mucosal and connective tissue mast cells.

4

Fig.12.10

Secreted factors from activated mast cells

5

Fig. 12.12

Secreted factors from activated eosinophils

6

Fig.12.16

Acute ,Late, and Chronic phase Type I Reactions.

Fig.12.18

Treatment of Type I Hypersensitivity

7

Fig. 13.8

Type II Cytotoxicreaction

SERUM SICKNESS (Type III hypersensitivity reaction)

8

ARTHUS REACTION (Type III hypersensitivity reaction)

9

Fig. 12.21

Delayed Type Hypersensitivity or DTH (Type IV hypersensitivity reaction)

10

ALLERGIC CONTACT DERMATITIS (Type IV hypersensitivity reaction)