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7th
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Physical Education and Sport Sciences �#�$"%&''(�����)"�* March 2010 –Tehran, Iran
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��References:��
1.Franks S, McCarthy M. Genetics of ovarian disorders: Polycystic ovary syndrome . Rev Endocr Metab Disord. 2004; 5(1):69-76. 2. Vigorito, C., Giallauria, F., Palomba, S., Cascella, T., Manguso, F., Lucci, R., De Lorenzo, A., Tafuri, D., Lombardi, G., Colao, A. & Orio, F. (2007) Beneficial effects of a three-month structured exercise training program on the cardiopulmonary functional capacity in young women with polycystic ovary syndrome. Journal of Clinical Endocrinology and Metabolism, 92, 1379–1384. 3. Palomba1 S ,. Giallauria F, Falbo1 A, Russo T, Oppedisano R, Tolino A, Colao A,Vigorito C, Zullo F , Orio F. Structured exercise training programme versus hypocaloric hyperproteic diet in obese polycystic ovary syndrome patients with anovulatory infertility: a 24-week pilot study. Human Reproduction 2007;1–9. 4. Orio, F. Jr, Giallauria, F., Palomba, S., Cascella, T., Manguso, F., Vuolo, L., Russo, T., Tolino, A., Lombardi, G., Colao, A. & Vigorito, C. (2006) Cardiopulmonary impairment in young women with polycystic ovary syndrome. Journal of Clinical Endocrinology and Metabolism, 91, 2967–2971. 5. Orio, F. Jr, Palomba, S., Spinelli, L., Cascella, T., Tauchmanovà, L., Zullo, F., Lombardi, G. & Colao, A. (2004) The cardiovascular risk of young women with polycystic ovary syndrome: an observational, analytical, prospective case-control study. Journal of Clinical Endocrinology and Metabolism, 89, 3696–3701. 6. Birdsall, M.A., Farquar, C.M. & White, H.D. (1997) Association between polycystic ovaries and extent of coronary artery disease in women having cardiac catheterization. Annals of International Medicine, 126, 32–35.
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7th
International Congress on
Physical Education and Sport Sciences �#�$"%&''(�����)"�* March 2010 –Tehran, Iran
Effect of 12 week aerobic training program on cardiovascular risk factors,
hormonal and metabolical alterations in young women with polycystic ovary
syndrome
Sardar. Mohammadali (PhD) : Mashhad Medical Sciences University-sardarma@mums.ac.ir
Attarzadeh reza (PhD) : Ferdowsi University of mashad- attarzadeh@ferdoesi.um.ac.ir
Taghavi morteza(PhD) : Mashhad Medical Sciences University - e-mail :taghavi@mums.ac.ir
Ayaz fahimeh(MA) : Mashhad Medical Sciences University - fahimehayaz@yahoo.com
Introduction:Polycystic ovary syndrome (Pcos) is an endocrine disease which is
characterized by un ovulation, hirsutism, acne, hyperandrogenism, impaired glucose
tolerance, insulin resistance and obesity(1) . Life style modifications are successfully
employed to treat obese and over weight women with Pcos. In spite of these CVR
factors metabolic disorders, increased impaired glucose tolerance, diabetes and also
dislipidimia, there are no adequate data documenting the effects of a structured
aerobic exercise program in Pcos women(2). The aim of this study was to evaluate the
effect of aerobic training program on the obesity and insulin resistance in young
women with Pcos.��
Methods: This study was semiexprimental and pre-post test design was used.
Statistical society of the study includes all patients with Pcos who were under
treatment in special clinic of Qaem hospital in Mashad. Statistical samples were 20
patient with Pcos aged 15-25 years old who voluntarily participated in program.
Aerobic training program was performed for 12-weeks, 3 sessions per week, 45-60
minutes per session on bicycle ergometer, elliptical, treadmill with the intensity of
50-60 %vo2max(3).Body weight, FAT% , BMI, WHR, WC, Cl ,TG, HDL-C, LDL-C,
Fasting glucose, Fasting insulin, Insulin Resistance, LH, FSH, Testosterone, DHEA
were assessed at base line and after 12-week aerobic training program. Smirnov-
Kolmogrov test was used to insuring of natural data disturbances. Deference between
means of pre and post training was assessed through dependent t student test with
p<0/05.
Results: After 12-week aerobic training program showed significant improvements in
BW, WC, FAT% , Vo2max, LH, CL, HDL-C, LDL-C, but changes in BMI, WHR,
Fasting glucose, Fasting insulin, IR, FSH, Testosterone, DHEA, and TG were not
significant.
Conclusions: 12-week aerobic training program improves some of the
anthropometric parameters, metabolic and hormonal profiles. To day it no known that
Pcos patient showed impaired maximal and sub maximal cardiopulmonary responses
to exercise compared with age and BMI matched healthy women(4). These finding
seems to be related to several mechanisms and factors including IR and myocardial
and skeletal muscle energy metabolism(5,6). Therefore pcos women should follow an
aerobic training program throughout life in order to improve cardiopulmonary
functional capacity and insulin sensitivity parameters conferring a significant long-
term prognostic advantage. Further studies will be mandatory to extend our results to
a larger and older pcos women population.
Key words: polycystic ovary syndrome (Pcos), obesity, insulin resistance, aerobic
training.�
����������� �������� ����������������������� ���� !"� �
7th
International Congress on
Physical Education and Sport Sciences �#�$"%&''(�����)"�* March 2010 –Tehran, Iran
References: 1.Franks S, McCarthy M. Genetics of ovarian disorders: Polycystic ovary syndrome . Rev Endocr Metab Disord. 2004; 5(1):69-76. 2. Vigorito, C., Giallauria, F., Palomba, S., Cascella, T., Manguso, F., Lucci, R., De Lorenzo, A., Tafuri, D., Lombardi, G., Colao, A. & Orio, F. (2007) Beneficial effects of a three-month structured exercise training program on the cardiopulmonary functional capacity in young women with polycystic ovary syndrome. Journal of Clinical Endocrinology and Metabolism, 92, 1379–1384. 3. Palomba1 S ,. Giallauria F, Falbo1 A, Russo T, Oppedisano R, Tolino A, Colao A,Vigorito C, Zullo F , Orio F. Structured exercise training programme versus hypocaloric hyperproteic diet in obese polycystic ovary syndrome patients with anovulatory infertility: a 24-week pilot study. Human Reproduction 2007;1–9. 4. Orio, F. Jr, Giallauria, F., Palomba, S., Cascella, T., Manguso, F., Vuolo, L., Russo, T., Tolino, A., Lombardi, G., Colao, A. & Vigorito, C. (2006) Cardiopulmonary impairment in young women with polycystic ovary syndrome. Journal of Clinical Endocrinology and Metabolism, 91, 2967–2971. 5. Orio, F. Jr, Palomba, S., Spinelli, L., Cascella, T., Tauchmanovà, L., Zullo, F., Lombardi, G. & Colao, A. (2004) The cardiovascular risk of young women with polycystic ovary syndrome: an observational, analytical, prospective case-control study. Journal of Clinical Endocrinology and Metabolism, 89, 3696–3701. 6. Birdsall, M.A., Farquar, C.M. & White, H.D. (1997) Association between polycystic ovaries and extent of coronary artery disease in women having cardiac catheterization. Annals of International Medicine, 126, 32–35.�
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