carbohydrate of brain tissue
Post on 12-Aug-2015
70 Views
Preview:
TRANSCRIPT
CARBOHYDRATE OF BRAIN TISSUE
• Triosephosphate• Hexose• Lactic acid• Pyruvic acid
Minerals: Ion, macromolecules and micromolecules.
Na, K, Cu, Fe, Ca, Mg and P
Metabolism of nervous tissue
1. Needs high amount of energy2. Even higher in grey matter 3. Aerobic environment4. Anabolism takes place too5. Main substrate is glucose6. Metabolism of amino acids
NEUROTRANSMITTERS
1- Most are synthesized in presynaptic terminal
2- Once synthesized, they are stored in vesicles
3- Released in response to nerve impulse: 4- Termination: by: Reuptake of the neurotransmitter into presynaptic terminal Or Enzymatic inactivation
Glutamate Glutamine
Glutaminase
Metabolism of Ammonia
Hyperammonia – 1. Stops Kreb’s cycle
2. Depletion of ATP 3. Accumulation of
Glu and Gln
4. Changes in osmosis
5. Influx of water
top related