challenges of incorporating functional ingredients into ...0 10 20 30 40 50 min mau 0 100 200 300...

Customer Focused, Science Driven, Results Led

Challenges of Incorporating Functional Ingredients into Foods - An NPD and Analytical Perspective

Jane Staniforth & Robert Griffiths

• Introduction to RSSL

•What is meant by Functional Ingredients?

•The development brief

•Analytical considerations

•Case studies

Overview

•We provide science and technology outsourcing to the global food, healthcare and pharmaceutical industries

•Key areas of expertise for food sector include: Functional Foods & Ingredients Allergens Analysis & Consultancy Contaminant Investigative Analysis Product Development

What Do We Do at RSSL?

Definition of Functional Ingredient

Ingredients that provide some health benefit above and beyond fulfilling basic nutrition (health-promotion)

Vitamins

Omega-3

Antioxidants

Plant sterols

Minerals

Proteins

Challenge Your Development Brief

• What is the product?

• What functional ingredients are to be added?

• What claims do you want to make?

• What is the target shelf life?

What

• Where will it be manufactured?

• Where will the product be stored?

Where

• When is product due to be launched?

• When is product to be consumed? How often? When

• Who is target retailer?

• Who is the target consumer? Who

Know what product you want…….

but more importantly……

know what product you do not want

Key Challenge

Challenges For The Developer

•Scrutinise original concept •Sensory attributes •Choice of ingredient(s) •Quality of ingredient / supplier •Active levels • Incorporation of active/raw material •Stability of ingredient & product •Storage conditions •Packaging

•Raw material assessment

•Development process

•Label claims

•Shelf life

•Troubleshooting

•Due diligence

Why Analyse?

•Sampling

•Stability

•Active form

•Method selection

•Extraction

•Sensitivity

•Speed, robustness

Challenges For Analysts

Case Study: Omega 3 & 6 Fatty Acids

Development Challenges

•Select the optimum source of active

•Flavour selection

•Taste optimisation

•Consider how being consumed

•Source of ingredient

•Component of interest

• Is the product fortified?

•Form of ingredient

•Nature of finished product

• Ingredient stability

Analytical Challenges

Outline of Method

Sampling

Extraction

Derivatisation

Instrumentation GC

Results

Case Study: Botanicals

Challenges

•Are you claiming an amount of active or plant extract?

•Are you are looking at a mixture of botanicals?

•Carotenoids methodology vs forms

•Stability of active

Botanical Active

Green Tea Catechins

Guarana Caffeine

Echinacea Chlorogenic acid

Pomegranate Ellagic acid

Soy Isoflavones

Ginseng Ginsenosides

Example of Chromatography Of Markers Used For Stability

min 0 5 10 15 20 25 30 35 40 45

mAU

0

200

400

600

800

1000

DAD1 B, Sig=220,4 Ref=580,40 (I:\ANP_VNP\NATPROD2\1\DATA\VAL2515\12815'1.D)

min0 10 20 30 40 50

mAU

0

100

200

300

400

500

600

700

800

DAD1 B, Sig=220,4 Ref =590,20 (I:\ANP_VNP\NATPROD1\DATA\NB28126\008-0901.D)

min0 10 20 304050

mAU

0

100

200

300

400

500

600

700

DAD1 B, Sig=220,4 Ref=590,20 (I:\ANP_VNP\NATPROD1\DATA\SAL21125\122517.D)

24 months

12 months

0 months

Lots to consider to ensure a successful product…

Development Support:

•Ensure development brief is very specific and achievable

• Incorporate the correct amount of ingredient to make any claims

•Start analytical validation and checking at the earliest point possible

Get The Most Out Of Your NPD Team

Get The Most Out Of Your Analyst

Analytical Support:

•Consult at early stage •Check method available • Ingredient details •Product information •Homogenous sample •Transport of sample •Manufacturing process

Ensure your expectations…..

and the abilities of your partner organisation…..

are matched

• New forms of ingredients

• Legislation changes

• New products

• Increased dosage

• Combinations of ingredients

• Method developments

• Media attention

Future Challenges

Any Questions?

Thank You For Your Attention

Jane Staniforth & Robert Griffiths

Jane.Staniforth@rssl.com Robert.G.Griffiths@rssl.com