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Customer Focused, Science Driven, Results Led
Challenges of Incorporating Functional Ingredients into Foods - An NPD and Analytical Perspective
Jane Staniforth & Robert Griffiths
• Introduction to RSSL
•What is meant by Functional Ingredients?
•The development brief
•Analytical considerations
•Case studies
Overview
•We provide science and technology outsourcing to the global food, healthcare and pharmaceutical industries
•Key areas of expertise for food sector include: Functional Foods & Ingredients Allergens Analysis & Consultancy Contaminant Investigative Analysis Product Development
What Do We Do at RSSL?
Definition of Functional Ingredient
Ingredients that provide some health benefit above and beyond fulfilling basic nutrition (health-promotion)
Vitamins
Omega-3
Antioxidants
Plant sterols
Minerals
Proteins
Challenge Your Development Brief
• What is the product?
• What functional ingredients are to be added?
• What claims do you want to make?
• What is the target shelf life?
What
• Where will it be manufactured?
• Where will the product be stored?
Where
• When is product due to be launched?
• When is product to be consumed? How often? When
• Who is target retailer?
• Who is the target consumer? Who
Know what product you want…….
but more importantly……
know what product you do not want
Key Challenge
Challenges For The Developer
•Scrutinise original concept •Sensory attributes •Choice of ingredient(s) •Quality of ingredient / supplier •Active levels • Incorporation of active/raw material •Stability of ingredient & product •Storage conditions •Packaging
•Raw material assessment
•Development process
•Label claims
•Shelf life
•Troubleshooting
•Due diligence
Why Analyse?
•Sampling
•Stability
•Active form
•Method selection
•Extraction
•Sensitivity
•Speed, robustness
Challenges For Analysts
Case Study: Omega 3 & 6 Fatty Acids
Development Challenges
•Select the optimum source of active
•Flavour selection
•Taste optimisation
•Consider how being consumed
•Source of ingredient
•Component of interest
• Is the product fortified?
•Form of ingredient
•Nature of finished product
• Ingredient stability
Analytical Challenges
Outline of Method
Sampling
Extraction
Derivatisation
Instrumentation GC
Results
Case Study: Botanicals
Challenges
•Are you claiming an amount of active or plant extract?
•Are you are looking at a mixture of botanicals?
•Carotenoids methodology vs forms
•Stability of active
Botanical Active
Green Tea Catechins
Guarana Caffeine
Echinacea Chlorogenic acid
Pomegranate Ellagic acid
Soy Isoflavones
Ginseng Ginsenosides
Example of Chromatography Of Markers Used For Stability
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DAD1 B, Sig=220,4 Ref=580,40 (I:\ANP_VNP\NATPROD2\1\DATA\VAL2515\12815'1.D)
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DAD1 B, Sig=220,4 Ref =590,20 (I:\ANP_VNP\NATPROD1\DATA\NB28126\008-0901.D)
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DAD1 B, Sig=220,4 Ref=590,20 (I:\ANP_VNP\NATPROD1\DATA\SAL21125\122517.D)
24 months
12 months
0 months
Lots to consider to ensure a successful product…
Development Support:
•Ensure development brief is very specific and achievable
• Incorporate the correct amount of ingredient to make any claims
•Start analytical validation and checking at the earliest point possible
Get The Most Out Of Your NPD Team
Get The Most Out Of Your Analyst
Analytical Support:
•Consult at early stage •Check method available • Ingredient details •Product information •Homogenous sample •Transport of sample •Manufacturing process
Ensure your expectations…..
and the abilities of your partner organisation…..
are matched
• New forms of ingredients
• Legislation changes
• New products
• Increased dosage
• Combinations of ingredients
• Method developments
• Media attention
Future Challenges
Any Questions?
Thank You For Your Attention
Jane Staniforth & Robert Griffiths