epidemiology of wolff- parkinson-white syndrome in...

Epidemiology of Wolff- Parkinson-

White Syndrome in Singapore

---- A Preliminary result

Hossain SM, Bai Rong, Ching Chi

Keong, Jack Tan, Kuik Hwee Bing,

Ruth Kam, Teo Wee Siong

Objective

To find out the age, sex and racial

distributions of WPW syndrome

among the multi-ethnic

Singapore population.

Clinical significance of WPW

syndrome study

Associated with high frequency of

arrhythmias.

It shows bizarre and misleading

electrocardiographic pattern.

Can be cured by catheter ablation.

12 lead ECG showing different WPW

pathway

Manifest WPW

Methods

A retrospective study done in all WPW syndrome

patients admitted in NHC for catheter ablation from

Oct ’1991 to Dec’03.

Statistical analysis by chi-square and cross

tabulation methods.

Accessory pathway is determined by

• History and physical examination

• Analysis of surface 12 lead ECG

• Intracardiac mapping by EPS

Picture of normal conductive

system and wpw PATHWAY

Cinefilms to show intracardiac

catheters

Result

Male

N=462

Female

N=289

Total

N=751

M:F

1.6:1

Age 37±14 41±15 38±15 <0.01

Race

1) Chinese

2) Malay

3) Indian

4) Others

403

37

9

13

256

22

7

4

659

59

16

17

Single

pathway

432 273 705 (94%)

Multiple

pathway

30 16 46 (6%)

Bar chart showing the age

distributions in Single AP

AGE_GRP

70-7960-6950-5940-4930-3920-2910-19

Pe

rce

nt

30

28

26

24

22

20

18

16

14

12

10

8

6

4

20

Pie chart showing the percentage of the

each site in Single Accessory Pathway

3.5%

12.3%

3.0%

12.9%

68.2%

Others

Posteroseptal

Anteroseptal

Right free wall

Left free wall

Result - Racial distribution in

single pathway

Chinese Malay Indian Others p-value

Single pathway

1) LFW

2) RFW

3) Anteroseptal

4) Posteroseptal

5) Others

422

79

21

73

21

40

4

0

10

3

11

3

0

2

0

8

5

0

2

1

>0.05

X2 5.28 -5.64 -9.92 1.59

P-value <0.05 <0.05 <0.001 >0.05

Gender distribution in single

pathway

Male Female P-value

LFW 297 184

RFW 47 44

Anteroseptal 15 6

Posteroseptal 64 23

Others 9 16

<0.05

Conclusion

Male suffers more from WPW syndrome .

Highest incidence observed in 3rd and 4th

decade.

In Singapore LFW also topped the list

among the WPW syndrome pathways.

Thank you!