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Yang et al. (2003) Am. J. Hum. Genet 73: 627

• ACTN3+�¹��*<BNj¤¸MjZBÑα-ctinin-3:E�S�$�7• <efX+�ÖÉESj)4!$α-ctinin-3�Ä7�&�%�(�• a-actinin-3*đ�+a-actinin-2)4!$į��87��ACTN3*Įùç*·��5�ę�n(7&®98$��

126,559i�*�(�E��\dC��GWAS

• Fig. 1*3"*SNPs+��*¯�ėÏęŊ('&*<LG?�Gcj%2¦Ý�8��Rietveld et al. 2014, PNAS 13790, Ward et al. 2014 PLoS ONE e100248)

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Rietveld et al. (2013) Science 340: 1467

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5Yano et al. (2016) Nature Genetics 48: 927

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Garcia-Ruiz et al. Proc Natl Acad Sci 113(28): E3995-4004

“The most dramatic response to genomic selection was observed for the lowly heritable traits DPR, PL, and SCS. Genetic trends changed from close to zero to large and favorable, resulting in rapid genetic improvement in fertility, lifespan, and health in a breed where these traits eroded over time.”

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