pharmarc smma insights about rheumatoid arthritis from twitter data
Post on 20-Jun-2015
2.668 Views
Preview:
DESCRIPTION
TRANSCRIPT
www.pharmarc.com
PharmARC SMMA
Insights from Social Media Data Jan 2011 to July 2011 – Twitter data for rheumatoid arthritis
Tanmay Saraykar
Manager, Social Media Analytics
© PharmARC Analytic Solutions Pvt. Ltd., 2011. All Rights Reserved. Slide 2
Every Sunday, RA patients chat on Twitter using #rheum on
various topics related to rheumatoid arthritis
Sunday, January 09, 2011
Sunday, January 30, 2011
Sunday, March 06, 2011
Sunday, April 17, 2011
Sunday, June 05, 2011
Sunday, July 24, 2011
0
100
200
300
400
500
600
Daily count of tweets – Jan 2011 to July 2011
© PharmARC Analytic Solutions Pvt. Ltd., 2011. All Rights Reserved. Slide 3
RA Activities on Twitter – Overview
Twitter hashtag Definition: Words or phrases prefixed with a # sign,
used as text indicators to organize around an idea, tweet about certain
subjects, group posts around topics
Popular Twitter hashtag for rheumatoid arthritis: #rheum
Duration: January 2, 2011 to July 31, 2011
Total no. of tweets using #rheum – 16,524
Total tweeting accounts – 1160
No. of tweets for top 10% accounts – 13,049
(80%)
Top 10 % accounts are the most influential.
#rheum - Chats on Rheumatology topics:
Sundays at 3pm EST/8pm GMT. Use the
hashtag #rheum for rheumatology tweets
This hashtag is a Tweet Chat
© PharmARC Analytic Solutions Pvt. Ltd., 2011. All Rights Reserved. Slide 4
Sample tweets from patients of rheumatoid arthritis
mouth sores from
Methotrexate
#rheum // if folic
acid doesn't work,
try folinic acid. A
rhubarb extract
may help healing.
So far I've been on
Plaquenil, MTX,
Arava and Enbrel.
My rheumy has
now prescribed
Humira. #rheum
Perfect post today. I
have PsA and
#rheum just put me
on Methotrexate
recently since my
Enbrel stopped
working. Need
positives.
P Enbrel works for
me! Humira gave
me headache all
day everyday for
entire 2 mos. I
used it. #rheum
commented on
your Humira post;
I had no luck with
it either, but
Rituximab has
changed my life,
so there is hope
#rheum
#Rheum doc appt
went well. Switching to
injection & upping
dose of Methotrexate.
Go back in 2mths; 2
consider Remicade in
place of Enbrel.
Uggity.
Painsomnia stinks.
Been up 5 hrs
after sleep for 3.
This is gonna be a
JOY of a day. And
Enbrel delivery!
#rheum
MTX: 3 years,
Rituximab: 3 years,
Prednisolone: 6
years. Tried
everything from
Anti-TNF to
plaquenil in-
between #rheum
© PharmARC Analytic Solutions Pvt. Ltd., 2011. All Rights Reserved. Slide 5
Chat Topics – January 2011
(Sundays – 2nd, 9th, 16th, 23rd and 30th)
1. How many RA patients manage to work full time, part time? For
how many years? How about working from home?
2. New year resolutions for RA patients
3. Patients bringing in information about RA, does it bother
doctors? What about writing to doctors or commenting on blogs?
4. Favorite stress relievers for patients, rewards and comforts
5. Do you do what the doctor says? If not, do you tell the doctor?
6. Are online support groups better than local support groups?
Why?
7. Annual RA meet-up
8. Depression from chronic pain
• Suggestions to avoid or combat depression
• What can friends, family members, doctor do to help
depression from chronic pain?
9. Most important suggestions to patients newly
diagnosed with RA
Chat Topics from Chats on Twitter with #rheum Standard Twitter Chat Rules
1. Tweets assumed to be your
own opinion
2. Do not sell
3. Politely stay on topics
Social Essence
1. Professional life of RA
patients
2. Pain management
3. Stress relief and hobbies
4. Compliance to prescription
drugs
5. Social information sharing
and support groups
6. Annual events
7. Emotional issues related to
chronic pain from RA
8. Helping newly diagnosed
patients
© PharmARC Analytic Solutions Pvt. Ltd., 2011. All Rights Reserved. Slide 6
Social media data reveals valuable insights about
critical parameters of prescription drugs
The insights
revealed through
social media
monitoring and
analysis can act
as decision-
making points for
consumers
Drug consumption/Comments
about Drug Brands
Drug efficacy, Side effects
Switch-overs
Convenience of dosage
Combination with other medication
© PharmARC Analytic Solutions Pvt. Ltd., 2011. All Rights Reserved. Slide 7
Social media reveals – Drug Consumption data for
various drug classes
#1
Which prescription drugs are being consumed by patients of rheumatoid
arthritis?
Drug Class Brands
DMARDs
Biologics
NSAIDs
Enbrel, Humira,
Remicade, Rituxan,
Orencia, Actemra,
Cimzia, Simponi, etc.
Drug consumption
© PharmARC Analytic Solutions Pvt. Ltd., 2011. All Rights Reserved. Slide 8
Analysis of tweets reveals buzz around rheumatoid
arthritis brand names – Tag clouds for brand names
Enbrel Humira
Remicade
Orencia
Actemra
Rituxan
Simponi Cimzia
Methotrexate
© PharmARC Analytic Solutions Pvt. Ltd., 2011. All Rights Reserved. Slide 9
Methotrexate is by far the most discussed, amongst
drugs (not surprising)
11
22
45
50
54
86
189
226
517
0 100 200 300 400 500 600
Cimzia (certolizumab)
Simponi (golimumab)
Rituxan (Rituximab)
Actemra (tocilizumab)
Orencia (abatacept)
Remicade (infliximab)
Humira (adalimumab)
Enbrel (etanercept)
Methotrexate
Total Mentions
© PharmARC Analytic Solutions Pvt. Ltd., 2011. All Rights Reserved. Slide 10
Social media reveals – Comments about efficacy
of drugs
Which prescription drugs work better than others? How do drugs compare on
efficacy as mentioned by patients?
Efficacy
Biologics - Half life of the drug
Positive efficacy
Negative efficacy
#2 Drug efficacy and Side effects
© PharmARC Analytic Solutions Pvt. Ltd., 2011. All Rights Reserved. Slide 11
Tweets by patients of rheumatoid arthritis reveal
insights regarding efficacy of biologics
22
18
2 3
2 2
9 9
0
3
0
2
0
5
10
15
20
25E
nb
rel
Hum
ira
Re
mic
ad
e
Ore
ncia
Acte
mra
Ritu
xan
Drug works for me Doesn’t work/worsened condition
© PharmARC Analytic Solutions Pvt. Ltd., 2011. All Rights Reserved. Slide 12
Social media data contains patients’ comments about side
effects of various drugs (methotrexate example)
10 10
9
6 6
4
3 3
2 2 2 2 2
0
2
4
6
8
10
12
Fatig
ue
Sto
ma
ch A
ch
e/Issu
es
Na
use
a
Ha
ir lo
ss/th
innin
g h
air
Sic
kn
ess
Fla
res
Biz
za
re d
rea
ms
Ab
do
min
al cra
mp
s
Insom
nia
Bre
ath
ing d
ifficu
lty
Vo
mitin
g
Alle
rgic
re
actio
n
Feve
r
Side effects of methotrexate from Twitter data
© PharmARC Analytic Solutions Pvt. Ltd., 2011. All Rights Reserved. Slide 13
Side effects of various biologics as mentioned by the
patients who are consuming them
Cough/Chronic respiratory
infection
Painsomnia
Joint and muscle pain (3)
Burning sensation (2)
Fatigue
Flares (2)
Fever
Gastrointestinal symptoms
Thinning hair
Nausea
Paleness
Mouth sores (2)
Flu like symptoms
Burning sensation (2)
Lowers ability to fight infection
Upper respiratory problems
Headache (2)
Nerve shock and numbness?
Lupus like and MS like symptoms
Inflammation
Sickness
Excessive was build-up in ears
(3)
Flares (2)
Lightheadedness, hot flashings,
chills
Fever
Rashes and bruising
Side effects - Enbrel Side effects - Humira
Sickness (1)
Side effects - Rituxan
© PharmARC Analytic Solutions Pvt. Ltd., 2011. All Rights Reserved. Slide 14
Side effects of various biologics as mentioned by the
patients who are consuming them
Hangover
Headache (2)
Ill feeling, fatigue
Allergic reaction (3)
Queasy and crackly feeling
Drop in blood pressure
Itch and bruises
Cough (4, with one
mentioning persistent, severe
cough)
Hives (2)
Allergic reaction (1)
Side effects - Remicade Side effects - Orencia Side effects - Actemra
© PharmARC Analytic Solutions Pvt. Ltd., 2011. All Rights Reserved. Slide 15
Social media reveals – comments on switch-overs
When one biologic drug or DMARD stops working for an RA patient, which
one do they switch to?
Switch-overs
Reasons for
switching drug class
Reasons for
switching brands
within a drug class
#3 Drug switch-overs
© PharmARC Analytic Solutions Pvt. Ltd., 2011. All Rights Reserved. Slide 16
For patients of rheumatoid arthritis, social media data reveals switch-
overs from one drug class to another (From DMARDs to Biologics) as
well as within a certain drug class (within biologics)
Switchover to Enbrel from Switchover from Enbrel to
Methotrexate
Humira
Unspecified
3
1
2
Methotrexate
1
5 Humira
Remicade
2
1
Unspecified
Orencia
1
© PharmARC Analytic Solutions Pvt. Ltd., 2011. All Rights Reserved. Slide 17
Summary of switch-overs between RA brands (38) – Combining insights from all social media platforms should reveal substantial insights (example below is from twitter)
© PharmARC Analytic Solutions Pvt. Ltd., 2011. All Rights Reserved. Slide 18
Analysis of 38 switch-overs mentioned in tweets indicate
that efficacy is a significant reason for switch over
Helps with other
indication 3%
Previous drug stops working
24%
Not specified 68%
Side effect 5%
© PharmARC Analytic Solutions Pvt. Ltd., 2011. All Rights Reserved. Slide 19
Social media reveals – what drug combinations the
patients are on
For treatment of RA, which combinations of drugs are taken by patients?
Switch-overs
DMARDs and
Biologics
NSAIDs and Pain
Killers
Anti-depressants
#4 Drug combinations
© PharmARC Analytic Solutions Pvt. Ltd., 2011. All Rights Reserved. Slide 20
Methotrexate is used in combination with various
biologics for treatment of rheumatoid arthritis
1
1
2
3
12
18
0 5 10 15 20
MTX and Actemra
MTX and Cimzia
MTX and Rituximab
MTX and Orencia
MTX and Humira
MTX and Enbrel
Combinations of methotrexate with biologics
NSAIDs/Pain
Killers/Others
Sulfasalazine
Prednisone
Mobic
Ibuprofen
Naproxen
Anti-acidity
Anti-depressant
Folic Acid
© PharmARC Analytic Solutions Pvt. Ltd., 2011. All Rights Reserved. Slide 21
Social media reveals – comments on convenience
of dosage for RA drugs
What are the issues associated with administering biologics to RA patients?
Convenience
DMARDs
Biologics
#5 Convenience of dosage
© PharmARC Analytic Solutions Pvt. Ltd., 2011. All Rights Reserved. Slide 22
RA patients post comments about convenience of dosage for
DMARDs and biologic drugs
DMARD - methotrexate Biologic - Enbrel
Positives Negatives
Methotrexate stays
longer in the body
Methotrexate
injections cause
less stomach
problems
Methotrexate takes
time to become
active in the body
Methotrexate oral
medication causes
nausea
Enbrel can sustain
in good condition
for 4 days at room
temperature, easy
to carry during
travel
Often causes
swelling at the
injection site
If injected in the
stomach, leaves
bruises
Patients need to
put ice at the
injection site which
is inconvenient
Doesn’t stay for
long in the body
Needed in more
volumes and
frequent injections
Positives Negatives
© PharmARC Analytic Solutions Pvt. Ltd., 2011. All Rights Reserved. Slide 23
Trends from social media data - Conversations about rheumatoid
arthritis on social media platforms revolve around three main topics
Drugs/Brands for treating RA Pain/inflammation management Emotional issues
• Parameters of RA drugs
(such as DMARDs and
Biologics), on the basis of
which, patients take
decisions, e.g.
• Efficacy
• Side effects
• Switch-overs
• Convenience of
dosage
• Costs
• Discussions around
reasons for switching over
between drug classes as
well as switching brands
within a drug class
• Discussions around
medication and alternative
therapies needed to treat
the side effects of RA
drugs
• Patients discuss the drugs
consumed for managing
chronic pain and
inflammation such as
NSAIDs and pain killers
• Discussions around
household therapies and
alternative therapies for
relieving pain
• Patients share tips for
managing the
inconvenience during
biologic infusions
• Patients share information
about precautions to be
taken against
pain/inflammation during
different seasons, as
severe weather conditions
may elevate RA-related
symptoms
• Patients show strong
empathy and concern on
social networks about
fellow RA patients
• They encourage sharing
issues relating to family,
livelihood, friends,
important events (e.g.
undergoing some surgery,
pregnancy, etc.) to gain
emotional and social
support
• RA patients express
depression due to chronic
pain and immobility as a
major concern
© PharmARC Analytic Solutions Pvt. Ltd., 2011. All Rights Reserved. Slide 24
Conclusion
Continuous monitoring and analysis of healthcare-related social
media data reveals insights into critical aspects of prescription
drugs, and helps understand the consumers better
Corporate Headquarters
PharmARC Analytic Solutions Pvt. Ltd.
Mercury 2B Block, 6th Floor
Prestige Technology Park
Sarjapur - Marathahalli Outer Ring Road
Bangalore 560 103, India
T +91 (80) 4123 8900
F +91 (80) 4123 8999
Europe
PharmARC Consulting Services GmbH
Passage 6
4104 Oberwil (BL)
Switzerland
T +41 (61) 261 8900
F +41 (61) 261 8901
USA
PharmARC Inc.
100 Overlook Center
2nd Floor, Princeton, NJ 08540
USA
T +1 (609) 450 1880
F +1 (609) 895 2666
© PharmARC Analytic Solutions Pvt. Ltd., 2011. All Rights Reserved.
For further information on this document, please contact:
Tanmay Saraykar
Manager, Social Media Analytics
+91 7829909766
tanmay.saraykar@pharmarc.com
top related