signal transduction
Post on 25-Dec-2015
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Signal Transduction
NFAT, a transcriptional regulator of interleukin-2 (IL-2) gene expression, is a direct target of calcineurin.
Calcineurin dephosphorylates the cytosolic component of NFAT, NFATc, which migrates to the nucleus and induces transcription of the IL-2 gene.
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