an xpd mouse model for the combined xeroderma pigmentosum/cockayne syndrome exhibiting both cancer...

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An Xpd mouse model for the combined xeroderma pigmentosum/Cockayne syndrome exhibiting both cancer predisposition and segmental progeria Jaan-Olle Andressoo, James R. Mitchell, Jan de Wit, Deborah Hoogstraten, Marcel Volker, Wendy Toussaint, Ewoud Speksnijder, Rudolph B. Beems, Harry van Steeg, Judith Jans, Chris I. de Zeeuw, Nicolaas G.J. Jaspers, Anja Raams, Alan R. Lehmann, Wim Vermeulen, Jan H.J. Hoeijmakers, Gijsbertus T.J. van der Horst Cancer Cell Volume 10, Issue 2, Pages 121-132 (August 2006) DOI: 10.1016/j.ccr.2006.05.027 Copyright © 2006 Elsevier Inc. Terms and Conditions

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Page 1: An Xpd mouse model for the combined xeroderma pigmentosum/Cockayne syndrome exhibiting both cancer predisposition and segmental progeria Jaan-Olle Andressoo,

An Xpd mouse model for the combined xeroderma pigmentosum/Cockayne syndrome exhibiting both cancer predisposition and segmental progeria 

Jaan-Olle Andressoo, James R. Mitchell, Jan de Wit, Deborah Hoogstraten, Marcel Volker, Wendy Toussaint, Ewoud Speksnijder, Rudolph B. Beems, Harry van Steeg, Judith Jans, Chris I. de Zeeuw, Nicolaas G.J. Jaspers, Anja Raams, Alan R. Lehmann, Wim

Vermeulen, Jan H.J. Hoeijmakers, Gijsbertus T.J. van der Horst 

Cancer Cell Volume 10, Issue 2, Pages 121-132 (August 2006)

DOI: 10.1016/j.ccr.2006.05.027

Copyright © 2006 Elsevier Inc. Terms and Conditions

Page 2: An Xpd mouse model for the combined xeroderma pigmentosum/Cockayne syndrome exhibiting both cancer predisposition and segmental progeria Jaan-Olle Andressoo,

Figure 1

Cancer Cell 2006 10, 121-132DOI: (10.1016/j.ccr.2006.05.027) Copyright © 2006 Elsevier Inc. Terms and Conditions

Page 3: An Xpd mouse model for the combined xeroderma pigmentosum/Cockayne syndrome exhibiting both cancer predisposition and segmental progeria Jaan-Olle Andressoo,

Figure 2

Cancer Cell 2006 10, 121-132DOI: (10.1016/j.ccr.2006.05.027) Copyright © 2006 Elsevier Inc. Terms and Conditions

Page 4: An Xpd mouse model for the combined xeroderma pigmentosum/Cockayne syndrome exhibiting both cancer predisposition and segmental progeria Jaan-Olle Andressoo,

Figure 3

Cancer Cell 2006 10, 121-132DOI: (10.1016/j.ccr.2006.05.027) Copyright © 2006 Elsevier Inc. Terms and Conditions

Page 5: An Xpd mouse model for the combined xeroderma pigmentosum/Cockayne syndrome exhibiting both cancer predisposition and segmental progeria Jaan-Olle Andressoo,

Figure 4

Cancer Cell 2006 10, 121-132DOI: (10.1016/j.ccr.2006.05.027) Copyright © 2006 Elsevier Inc. Terms and Conditions

Page 6: An Xpd mouse model for the combined xeroderma pigmentosum/Cockayne syndrome exhibiting both cancer predisposition and segmental progeria Jaan-Olle Andressoo,

Figure 5

Cancer Cell 2006 10, 121-132DOI: (10.1016/j.ccr.2006.05.027) Copyright © 2006 Elsevier Inc. Terms and Conditions

Page 7: An Xpd mouse model for the combined xeroderma pigmentosum/Cockayne syndrome exhibiting both cancer predisposition and segmental progeria Jaan-Olle Andressoo,

Figure 6

Cancer Cell 2006 10, 121-132DOI: (10.1016/j.ccr.2006.05.027) Copyright © 2006 Elsevier Inc. Terms and Conditions