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Intake and serum profile of fatty acids are weakly correlatedConsumo y suero perfil debilwith global dietary quality in European adolescents.

Vyncke KE,Huybrechts I,Dallongeville J,Mouratidou T,Van Winckel MA,Cuenca-Garca M,Ottevaere C,Gonzlez-Gross M,Moreno LA,Kafatos AG,Leclercq C,Sjstrm M,Molnr D,Stehle P,Breidenassel C,Marcos A,Manios Y,Widhalm K,Gilbert CC,Gottrand F,De HenauwS;HELENA Study Group.SourceFuenteDepartment of Public Health, Ghent University, Ghent, Belgium; Research Foundation Flanders,Departamento de Salud Pblica, Universidad Ghent, Ghent, Blgica; Fundacin deinvestigacin Flanders, Bruselas, Blgica. Correo electronico: Krishna.Vyncke@UGent.be.Brussels, Belgium. Electronic address: Krishna.Vyncke@UGent.be.

AbstractOBJECTIVE:

OBJETIVOThe present study assessed whether compliance with the Food-Based Dietary Guidelines isEvaluar,related to habitual fatty acid (FA) intake and blood lipid parameters.

METHODS:MTODOSDietary information was collected by two non-consecutive 24-h recalls in 1804 European

adolescents. Compliance with the Food-Based Dietary Guidelines was expressed by calculating

the Diet Quality Index for Adolescents (DQI-A). Blood samples were collected in a randomly

selected subset (n = 552). Relations between FA intake/serum concentrations and DQI-A were

tested with multilevel regression analysis to correct for the study design (clustering within cities).Analyses were stratified for gender; age was entered as a covariate.RESULTS:Better DQI-A scores were related to increased proportional intakes of energy from totalfat, saturated FA, monounsaturated FA, and cholesterol (P < 0.001), whereas no significantassociation was observed with polyunsaturated FA intakes. In adolescents with highercompared with lower DQI-A scores, dairy products contributed more (21.0% versus 12.7%) andlow-nutrient, energy-dense items contributed less (17.2% versus 26.3%) to the intake of totalfat. A positive association was observed between the DQI-A scores and serum concentrationsof eicosapentaenoic acid and docosahexaenoic acid (all P < 0.005). The latter, however, wassignificant only in girls. In boys, higher DQI-A scores were inversely associated with serum

cholesterol concentrations (P < 0.05).CONCLUSION:Although compliance with the Food-Based Dietary Guidelines was not always associated with afavorable FA intake pattern, a significant favorable association with some serum biomarkerswas observed. This outcome underlines the importance of considering dietary habits instead ofsingle-nutrient intakes.Copyright 2013 Elsevier Inc. All rights reserved.

Physical activity and markers of insulin resistance inadolescents: role of cardiorespiratory fitness levels - theHELENA study.

Jimnez-Pavn D,Ruiz JR,Ortega FB,Martnez-Gmez D,Moreno S,Urzanqui A,Gottrand F,Molnr D,Castillo MJ,Sjstrm M,Moreno LA;on behalf of the HELENA Study group.Source

http://www.ncbi.nlm.nih.gov/pubmed?term=Vyncke%20KE%5BAuthor%5D&cauthor=true&cauthor_uid=23312763http://www.ncbi.nlm.nih.gov/pubmed?term=Vyncke%20KE%5BAuthor%5D&cauthor=true&cauthor_uid=23312763http://www.ncbi.nlm.nih.gov/pubmed?term=Huybrechts%20I%5BAuthor%5D&cauthor=true&cauthor_uid=23312763http://www.ncbi.nlm.nih.gov/pubmed?term=Huybrechts%20I%5BAuthor%5D&cauthor=true&cauthor_uid=23312763http://www.ncbi.nlm.nih.gov/pubmed?term=Huybrechts%20I%5BAuthor%5D&cauthor=true&cauthor_uid=23312763http://www.ncbi.nlm.nih.gov/pubmed?term=Dallongeville%20J%5BAuthor%5D&cauthor=true&cauthor_uid=23312763http://www.ncbi.nlm.nih.gov/pubmed?term=Dallongeville%20J%5BAuthor%5D&cauthor=true&cauthor_uid=23312763http://www.ncbi.nlm.nih.gov/pubmed?term=Dallongeville%20J%5BAuthor%5D&cauthor=true&cauthor_uid=23312763http://www.ncbi.nlm.nih.gov/pubmed?term=Mouratidou%20T%5BAuthor%5D&cauthor=true&cauthor_uid=23312763http://www.ncbi.nlm.nih.gov/pubmed?term=Mouratidou%20T%5BAuthor%5D&cauthor=true&cauthor_uid=23312763http://www.ncbi.nlm.nih.gov/pubmed?term=Mouratidou%20T%5BAuthor%5D&cauthor=true&cauthor_uid=23312763http://www.ncbi.nlm.nih.gov/pubmed?term=Van%20Winckel%20MA%5BAuthor%5D&cauthor=true&cauthor_uid=23312763http://www.ncbi.nlm.nih.gov/pubmed?term=Van%20Winckel%20MA%5BAuthor%5D&cauthor=true&cauthor_uid=23312763http://www.ncbi.nlm.nih.gov/pubmed?term=Van%20Winckel%20MA%5BAuthor%5D&cauthor=true&cauthor_uid=23312763http://www.ncbi.nlm.nih.gov/pubmed?term=Cuenca-Garc%C3%ADa%20M%5BAuthor%5D&cauthor=true&cauthor_uid=23312763http://www.ncbi.nlm.nih.gov/pubmed?term=Cuenca-Garc%C3%ADa%20M%5BAuthor%5D&cauthor=true&cauthor_uid=23312763http://www.ncbi.nlm.nih.gov/pubmed?term=Cuenca-Garc%C3%ADa%20M%5BAuthor%5D&cauthor=true&cauthor_uid=23312763http://www.ncbi.nlm.nih.gov/pubmed?term=Ottevaere%20C%5BAuthor%5D&cauthor=true&cauthor_uid=23312763http://www.ncbi.nlm.nih.gov/pubmed?term=Ottevaere%20C%5BAuthor%5D&cauthor=true&cauthor_uid=23312763http://www.ncbi.nlm.nih.gov/pubmed?term=Gonz%C3%A1lez-Gross%20M%5BAuthor%5D&cauthor=true&cauthor_uid=23312763http://www.ncbi.nlm.nih.gov/pubmed?term=Gonz%C3%A1lez-Gross%20M%5BAuthor%5D&cauthor=true&cauthor_uid=23312763http://www.ncbi.nlm.nih.gov/pubmed?term=Gonz%C3%A1lez-Gross%20M%5BAuthor%5D&cauthor=true&cauthor_uid=23312763http://www.ncbi.nlm.nih.gov/pubmed?term=Moreno%20LA%5BAuthor%5D&cauthor=true&cauthor_uid=23312763http://www.ncbi.nlm.nih.gov/pubmed?term=Moreno%20LA%5BAuthor%5D&cauthor=true&cauthor_uid=23312763http://www.ncbi.nlm.nih.gov/pubmed?term=Moreno%20LA%5BAuthor%5D&cauthor=true&cauthor_uid=23312763http://www.ncbi.nlm.nih.gov/pubmed?term=Kafatos%20AG%5BAuthor%5D&cauthor=true&cauthor_uid=23312763http://www.ncbi.nlm.nih.gov/pubmed?term=Kafatos%20AG%5BAuthor%5D&cauthor=true&cauthor_uid=23312763http://www.ncbi.nlm.nih.gov/pubmed?term=Kafatos%20AG%5BAuthor%5D&cauthor=true&cauthor_uid=23312763http://www.ncbi.nlm.nih.gov/pubmed?term=Leclercq%20C%5BAuthor%5D&cauthor=true&cauthor_uid=23312763http://www.ncbi.nlm.nih.gov/pubmed?term=Leclercq%20C%5BAuthor%5D&cauthor=true&cauthor_uid=23312763http://www.ncbi.nlm.nih.gov/pubmed?term=Leclercq%20C%5BAuthor%5D&cauthor=true&cauthor_uid=23312763http://www.ncbi.nlm.nih.gov/pubmed?term=Sj%C3%B6str%C3%B6m%20M%5BAuthor%5D&cauthor=true&cauthor_uid=23312763http://www.ncbi.nlm.nih.gov/pubmed?term=Sj%C3%B6str%C3%B6m%20M%5BAuthor%5D&cauthor=true&cauthor_uid=23312763http://www.ncbi.nlm.nih.gov/pubmed?term=Sj%C3%B6str%C3%B6m%20M%5BAuthor%5D&cauthor=true&cauthor_uid=23312763http://www.ncbi.nlm.nih.gov/pubmed?term=Moln%C3%A1r%20D%5BAuthor%5D&cauthor=true&cauthor_uid=23312763http://www.ncbi.nlm.nih.gov/pubmed?term=Moln%C3%A1r%20D%5BAuthor%5D&cauthor=true&cauthor_uid=23312763http://www.ncbi.nlm.nih.gov/pubmed?term=Moln%C3%A1r%20D%5BAuthor%5D&cauthor=true&cauthor_uid=23312763http://www.ncbi.nlm.nih.gov/pubmed?term=Stehle%20P%5BAuthor%5D&cauthor=true&cauthor_uid=23312763http://www.ncbi.nlm.nih.gov/pubmed?term=Stehle%20P%5BAuthor%5D&cauthor=true&cauthor_uid=23312763http://www.ncbi.nlm.nih.gov/pubmed?term=Breidenassel%20C%5BAuthor%5D&cauthor=true&cauthor_uid=23312763http://www.ncbi.nlm.nih.gov/pubmed?term=Breidenassel%20C%5BAuthor%5D&cauthor=true&cauthor_uid=23312763http://www.ncbi.nlm.nih.gov/pubmed?term=Breidenassel%20C%5BAuthor%5D&cauthor=true&cauthor_uid=23312763http://www.ncbi.nlm.nih.gov/pubmed?term=Marcos%20A%5BAuthor%5D&cauthor=true&cauthor_uid=23312763http://www.ncbi.nlm.nih.gov/pubmed?term=Marcos%20A%5BAuthor%5D&cauthor=true&cauthor_uid=23312763http://www.ncbi.nlm.nih.gov/pubmed?term=Marcos%20A%5BAuthor%5D&cauthor=true&cauthor_uid=23312763http://www.ncbi.nlm.nih.gov/pubmed?term=Manios%20Y%5BAuthor%5D&cauthor=true&cauthor_uid=23312763http://www.ncbi.nlm.nih.gov/pubmed?term=Manios%20Y%5BAuthor%5D&cauthor=true&cauthor_uid=23312763http://www.ncbi.nlm.nih.gov/pubmed?term=Manios%20Y%5BAuthor%5D&cauthor=true&cauthor_uid=23312763http://www.ncbi.nlm.nih.gov/pubmed?term=Widhalm%20K%5BAuthor%5D&cauthor=true&cauthor_uid=23312763http://www.ncbi.nlm.nih.gov/pubmed?term=Widhalm%20K%5BAuthor%5D&cauthor=true&cauthor_uid=23312763http://www.ncbi.nlm.nih.gov/pubmed?term=Widhalm%20K%5BAuthor%5D&cauthor=true&cauthor_uid=23312763http://www.ncbi.nlm.nih.gov/pubmed?term=Gilbert%20CC%5BAuthor%5D&cauthor=true&cauthor_uid=23312763http://www.ncbi.nlm.nih.gov/pubmed?term=Gilbert%20CC%5BAuthor%5D&cauthor=true&cauthor_uid=23312763http://www.ncbi.nlm.nih.gov/pubmed?term=Gilbert%20CC%5BAuthor%5D&cauthor=true&cauthor_uid=23312763http://www.ncbi.nlm.nih.gov/pubmed?term=Gottrand%20F%5BAuthor%5D&cauthor=true&cauthor_uid=23312763http://www.ncbi.nlm.nih.gov/pubmed?term=Gottrand%20F%5BAuthor%5D&cauthor=true&cauthor_uid=23312763http://www.ncbi.nlm.nih.gov/pubmed?term=Gottrand%20F%5BAuthor%5D&cauthor=true&cauthor_uid=23312763http://www.ncbi.nlm.nih.gov/pubmed?term=De%20Henauw%20S%5BAuthor%5D&cauthor=true&cauthor_uid=23312763http://www.ncbi.nlm.nih.gov/pubmed?term=De%20Henauw%20S%5BAuthor%5D&cauthor=true&cauthor_uid=23312763http://www.ncbi.nlm.nih.gov/pubmed?term=De%20Henauw%20S%5BAuthor%5D&cauthor=true&cauthor_uid=23312763http://www.ncbi.nlm.nih.gov/pubmed?term=De%20Henauw%20S%5BAuthor%5D&cauthor=true&cauthor_uid=23312763http://www.ncbi.nlm.nih.gov/pubmed?term=HELENA%20Study%20Group%5BCorporate%20Author%5Dhttp://www.ncbi.nlm.nih.gov/pubmed?term=HELENA%20Study%20Group%5BCorporate%20Author%5Dhttp://www.ncbi.nlm.nih.gov/pubmed?term=HELENA%20Study%20Group%5BCorporate%20Author%5Dhttp://www.ncbi.nlm.nih.gov/pubmed?term=Jim%C3%A9nez-Pav%C3%B3n%20D%5BAuthor%5D&cauthor=true&cauthor_uid=23301989http://www.ncbi.nlm.nih.gov/pubmed?term=Jim%C3%A9nez-Pav%C3%B3n%20D%5BAuthor%5D&cauthor=true&cauthor_uid=23301989http://www.ncbi.nlm.nih.gov/pubmed?term=Ruiz%20JR%5BAuthor%5D&cauthor=true&cauthor_uid=23301989http://www.ncbi.nlm.nih.gov/pubmed?term=Ruiz%20JR%5BAuthor%5D&cauthor=true&cauthor_uid=23301989http://www.ncbi.nlm.nih.gov/pubmed?term=Ruiz%20JR%5BAuthor%5D&cauthor=true&cauthor_uid=23301989http://www.ncbi.nlm.nih.gov/pubmed?term=Ortega%20FB%5BAuthor%5D&cauthor=true&cauthor_uid=23301989http://www.ncbi.nlm.nih.gov/pubmed?term=Ortega%20FB%5BAuthor%5D&cauthor=true&cauthor_uid=23301989http://www.ncbi.nlm.nih.gov/pubmed?term=Ortega%20FB%5BAuthor%5D&cauthor=true&cauthor_uid=23301989http://www.ncbi.nlm.nih.gov/pubmed?term=Mart%C3%ADnez-G%C3%B3mez%20D%5BAuthor%5D&cauthor=true&cauthor_uid=23301989http://www.ncbi.nlm.nih.gov/pubmed?term=Mart%C3%ADnez-G%C3%B3mez%20D%5BAuthor%5D&cauthor=true&cauthor_uid=23301989http://www.ncbi.nlm.nih.gov/pubmed?term=Mart%C3%ADnez-G%C3%B3mez%20D%5BAuthor%5D&cauthor=true&cauthor_uid=23301989http://www.ncbi.nlm.nih.gov/pubmed?term=Moreno%20S%5BAuthor%5D&cauthor=true&cauthor_uid=23301989http://www.ncbi.nlm.nih.gov/pubmed?term=Moreno%20S%5BAuthor%5D&cauthor=true&cauthor_uid=23301989http://www.ncbi.nlm.nih.gov/pubmed?term=Moreno%20S%5BAuthor%5D&cauthor=true&cauthor_uid=23301989http://www.ncbi.nlm.nih.gov/pubmed?term=Urzanqui%20A%5BAuthor%5D&cauthor=true&cauthor_uid=23301989http://www.ncbi.nlm.nih.gov/pubmed?term=Urzanqui%20A%5BAuthor%5D&cauthor=true&cauthor_uid=23301989http://www.ncbi.nlm.nih.gov/pubmed?term=Urzanqui%20A%5BAuthor%5D&cauthor=true&cauthor_uid=23301989http://www.ncbi.nlm.nih.gov/pubmed?term=Gottrand%20F%5BAuthor%5D&cauthor=true&cauthor_uid=23301989http://www.ncbi.nlm.nih.gov/pubmed?term=Gottrand%20F%5BAuthor%5D&cauthor=true&cauthor_uid=23301989http://www.ncbi.nlm.nih.gov/pubmed?term=Gottrand%20F%5BAuthor%5D&cauthor=true&cauthor_uid=23301989http://www.ncbi.nlm.nih.gov/pubmed?term=Moln%C3%A1r%20D%5BAuthor%5D&cauthor=true&cauthor_uid=23301989http://www.ncbi.nlm.nih.gov/pubmed?term=Moln%C3%A1r%20D%5BAuthor%5D&cauthor=true&cauthor_uid=23301989http://www.ncbi.nlm.nih.gov/pubmed?term=Castillo%20MJ%5BAuthor%5D&cauthor=true&cauthor_uid=23301989http://www.ncbi.nlm.nih.gov/pubmed?term=Castillo%20MJ%5BAuthor%5D&cauthor=true&cauthor_uid=23301989http://www.ncbi.nlm.nih.gov/pubmed?term=Castillo%20MJ%5BAuthor%5D&cauthor=true&cauthor_uid=23301989http://www.ncbi.nlm.nih.gov/pubmed?term=Sj%C3%B6str%C3%B6m%20M%5BAuthor%5D&cauthor=true&cauthor_uid=23301989http://www.ncbi.nlm.nih.gov/pubmed?term=Sj%C3%B6str%C3%B6m%20M%5BAuthor%5D&cauthor=true&cauthor_uid=23301989http://www.ncbi.nlm.nih.gov/pubmed?term=Sj%C3%B6str%C3%B6m%20M%5BAuthor%5D&cauthor=true&cauthor_uid=23301989http://www.ncbi.nlm.nih.gov/pubmed?term=Moreno%20LA%5BAuthor%5D&cauthor=true&cauthor_uid=23301989http://www.ncbi.nlm.nih.gov/pubmed?term=Moreno%20LA%5BAuthor%5D&cauthor=true&cauthor_uid=23301989http://www.ncbi.nlm.nih.gov/pubmed?term=Moreno%20LA%5BAuthor%5D&cauthor=true&cauthor_uid=23301989http://www.ncbi.nlm.nih.gov/pubmed?term=on%20behalf%20of%20the%20HELENA%20Study%20group%5BCorporate%20Author%5Dhttp://www.ncbi.nlm.nih.gov/pubmed?term=on%20behalf%20of%20the%20HELENA%20Study%20group%5BCorporate%20Author%5Dhttp://www.ncbi.nlm.nih.gov/pubmed?term=on%20behalf%20of%20the%20HELENA%20Study%20group%5BCorporate%20Author%5Dhttp://www.ncbi.nlm.nih.gov/pubmed?term=on%20behalf%20of%20the%20HELENA%20Study%20group%5BCorporate%20Author%5Dhttp://www.ncbi.nlm.nih.gov/pubmed?term=Moreno%20LA%5BAuthor%5D&cauthor=true&cauthor_uid=23301989http://www.ncbi.nlm.nih.gov/pubmed?term=Sj%C3%B6str%C3%B6m%20M%5BAuthor%5D&cauthor=true&cauthor_uid=23301989http://www.ncbi.nlm.nih.gov/pubmed?term=Castillo%20MJ%5BAuthor%5D&cauthor=true&cauthor_uid=23301989http://www.ncbi.nlm.nih.gov/pubmed?term=Moln%C3%A1r%20D%5BAuthor%5D&cauthor=true&cauthor_uid=23301989http://www.ncbi.nlm.nih.gov/pubmed?term=Gottrand%20F%5BAuthor%5D&cauthor=true&cauthor_uid=23301989http://www.ncbi.nlm.nih.gov/pubmed?term=Urzanqui%20A%5BAuthor%5D&cauthor=true&cauthor_uid=23301989http://www.ncbi.nlm.nih.gov/pubmed?term=Moreno%20S%5BAuthor%5D&cauthor=true&cauthor_uid=23301989http://www.ncbi.nlm.nih.gov/pubmed?term=Mart%C3%ADnez-G%C3%B3mez%20D%5BAuthor%5D&cauthor=true&cauthor_uid=23301989http://www.ncbi.nlm.nih.gov/pubmed?term=Ortega%20FB%5BAuthor%5D&cauthor=true&cauthor_uid=23301989http://www.ncbi.nlm.nih.gov/pubmed?term=Ruiz%20JR%5BAuthor%5D&cauthor=true&cauthor_uid=23301989http://www.ncbi.nlm.nih.gov/pubmed?term=Jim%C3%A9nez-Pav%C3%B3n%20D%5BAuthor%5D&cauthor=true&cauthor_uid=23301989http://www.ncbi.nlm.nih.gov/pubmed?term=HELENA%20Study%20Group%5BCorporate%20Author%5Dhttp://www.ncbi.nlm.nih.gov/pubmed?term=De%20Henauw%20S%5BAuthor%5D&cauthor=true&cauthor_uid=23312763http://www.ncbi.nlm.nih.gov/pubmed?term=De%20Henauw%20S%5BAuthor%5D&cauthor=true&cauthor_uid=23312763http://www.ncbi.nlm.nih.gov/pubmed?term=Gottrand%20F%5BAuthor%5D&cauthor=true&cauthor_uid=23312763http://www.ncbi.nlm.nih.gov/pubmed?term=Gilbert%20CC%5BAuthor%5D&cauthor=true&cauthor_uid=23312763http://www.ncbi.nlm.nih.gov/pubmed?term=Widhalm%20K%5BAuthor%5D&cauthor=true&cauthor_uid=23312763http://www.ncbi.nlm.nih.gov/pubmed?term=Manios%20Y%5BAuthor%5D&cauthor=true&cauthor_uid=23312763http://www.ncbi.nlm.nih.gov/pubmed?term=Marcos%20A%5BAuthor%5D&cauthor=true&cauthor_uid=23312763http://www.ncbi.nlm.nih.gov/pubmed?term=Breidenassel%20C%5BAuthor%5D&cauthor=true&cauthor_uid=23312763http://www.ncbi.nlm.nih.gov/pubmed?term=Stehle%20P%5BAuthor%5D&cauthor=true&cauthor_uid=23312763http://www.ncbi.nlm.nih.gov/pubmed?term=Moln%C3%A1r%20D%5BAuthor%5D&cauthor=true&cauthor_uid=23312763http://www.ncbi.nlm.nih.gov/pubmed?term=Sj%C3%B6str%C3%B6m%20M%5BAuthor%5D&cauthor=true&cauthor_uid=23312763http://www.ncbi.nlm.nih.gov/pubmed?term=Leclercq%20C%5BAuthor%5D&cauthor=true&cauthor_uid=23312763http://www.ncbi.nlm.nih.gov/pubmed?term=Kafatos%20AG%5BAuthor%5D&cauthor=true&cauthor_uid=23312763http://www.ncbi.nlm.nih.gov/pubmed?term=Moreno%20LA%5BAuthor%5D&cauthor=true&cauthor_uid=23312763http://www.ncbi.nlm.nih.gov/pubmed?term=Gonz%C3%A1lez-Gross%20M%5BAuthor%5D&cauthor=true&cauthor_uid=23312763http://www.ncbi.nlm.nih.gov/pubmed?term=Ottevaere%20C%5BAuthor%5D&cauthor=true&cauthor_uid=23312763http://www.ncbi.nlm.nih.gov/pubmed?term=Cuenca-Garc%C3%ADa%20M%5BAuthor%5D&cauthor=true&cauthor_uid=23312763http://www.ncbi.nlm.nih.gov/pubmed?term=Van%20Winckel%20MA%5BAuthor%5D&cauthor=true&cauthor_uid=23312763http://www.ncbi.nlm.nih.gov/pubmed?term=Mouratidou%20T%5BAuthor%5D&cauthor=true&cauthor_uid=23312763http://www.ncbi.nlm.nih.gov/pubmed?term=Dallongeville%20J%5BAuthor%5D&cauthor=true&cauthor_uid=23312763http://www.ncbi.nlm.nih.gov/pubmed?term=Huybrechts%20I%5BAuthor%5D&cauthor=true&cauthor_uid=23312763http://www.ncbi.nlm.nih.gov/pubmed?term=Vyncke%20KE%5BAuthor%5D&cauthor=true&cauthor_uid=23312763

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GENUD (Growth, Exercise, Nutrition and Development) Research Group, School of HealthSciences, University of Zaragoza, Zaragoza, Spain; Department of Medical Physiology, Schoolof Medicine, University of Granada, Granada, Spain; Unit for Preventive Nutrition, Departmentof Biosciences and Nutrition, Karolinska Institutet, Stockholm, Sweden.AbstractOBJECTIVE:

To analyze the association between objectively assessed physical activity (PA) and markers ofinsulin resistance (IR) in European adolescents and to examine whether the association ofobjectively assessed PA and markers of IR is modified by cardiorespiratory fitness (CRF).METHODS:A cross-sectional study at school setting was conducted in 1053 (554 girls) adolescents (12.5-17.5 yr). Weight, height, waist circumference, total body fat, PA (accelerometry), and CRF (20-m shuttle run test) were measured. Fasting insulin and glucose concentrations were measured,and homeostasis model assessment as well as quantitative insulin sensitivity check index werecomputed.RESULTS:In males, vigorous PA (VPA) was negatively associated with markers of IR after adjusting forconfounders including waist circumference (all p

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(P

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Skin tests were positive for casein in the patients. The prick-prick tests were positive for thethree cheeses in patients 1 and 4, for goat and sheep cheese in patients 2 and 3, and for sheepcheese in patient 5. The specific IgE test was positive in patients 1, 3 and 4 for goat and sheepcheese, and negative in patients 2 and 5. Serum 3 and 4 clearly recognised goat and sheepcheese extracts. Goat casein was almost completely inhibited with sheep casein and partiallyinhibited with goat and sheep serum proteins, while there was no inhibition with cow cheese.

Sheep casein was totally inhibited with sheep serum proteins. Sheep casein was inhibited withgoat and cow caseins, suggesting cross-reactivity among the three types of cheese.CONCLUSIONS:

We showed sensitisation to goat and sheep cheese in two patients, and only to sheep cheese inanother two of the studied patients.

Combined influence of healthy diet and active lifestyle oncardiovascular disease risk factors in adolescents.Cuenca-Garca M,Ortega FB,Ruiz JR,Gonzlez-Gross M,Labayen I,Jago R,Martnez-Gmez D,Dallongeville J,Bel-Serrat S,Marcos A,Manios Y,Breidenassel C,Widhalm K,Gottrand F,Ferrari M,Kafatos A,Molnr D,Moreno LA,De Henauw S,Castillo MJ,Sjstrm M;HELENA study group.Source

Department of Medical Physiology, School of Medicine, University of Granada, Granada, Spain;Unit for Preventive Nutrition, Department of Biosciences and Nutrition, Institute of Karolinska,Huddinge, Sweden.AbstractTo investigate the combined influence of diet quality and physical activity on cardiovasculardisease (CVD) risk factors in adolescents, adolescents (n=1513; 12.5-17.5 years) participatingin the Healthy Lifestyle in Europe by Nutrition in Adolescence study were studied. Dietary intakewas registered using a 24-h recall and a diet quality index was calculated. Physical activity wasassessed by accelerometry. Lifestyle groups were computed as: healthy diet and active,unhealthy diet but active, healthy diet but inactive, and unhealthy diet and inactive. CVD riskfactor measurements included cardiorespiratory fitness, adiposity indicators, blood lipid profile,blood pressure, and insulin resistance. A CVD risk score was computed. The healthy diet andactive group had a healthier cardiorespiratory profile, fat mass index (FMI), triglycerides, and

high-density lipoprotein cholesterol (HDL-C) levels and total cholesterol (TC)/HDL-C ratio (allP0.05). Overall, active adolescents showed higher cardiorespiratory fitness, lower FMI,TC/HDL-C ratio, and homeostasis model assessment index and healthier blood pressure thantheir inactive peers with either healthy or unhealthy diet (all P0.05). Healthy diet and activegroup had healthier CVD risk score compared with the inactive groups (all P0.02). Thus, acombination of healthy diet and active lifestyle is associated with decreased CVD risk inadolescents. Moreover, an active lifestyle may reduce the adverse consequences of anunhealthy diet.

Gender and age influence blood folate, vitamin B12, vitamin B6,and homocysteine levels in European adolescents: the HelenaStudy.Gonzlez-Gross M,Benser J,Breidenassel C,Albers U,Huybrechts I,Valtuea J,Spinneker A,

Segoviano M,Widhalm K,Molnar D,Moreno LA,Stehle P,Pietrzik K;HELENA Study group.SourceDepartment of Health and Human Performance, Facultad de Ciencias de la Actividad Fsica ydel Deporte-INEF, Universidad Politcnica de Madrid, Madrid, Spain.marcela.gonzalez.gross@upm.esAbstractIt is important to be able to evaluate vitamin status correctly at any age, but this is especiallyvital during adolescence since there are higher requirements for healthy growth anddevelopment. However, there are no currently available B-vitamin reference values for healthyadolescents. The aim of the present study is to assess the vitamin B status in Europeanadolescents in order to contribute to the development of reference values for selected B-vitamins and total homocysteine (tHcy). Within the HELENA (Healthy Lifestyle in Europe byNutrition in Adolescence) cross-sectional study, a sub sample of 1051 (499 males, 552 females)adolescents from ten European cities aged 12.5 to 17.49 were analyzed for fasting plasmafolate (PF), red blood cell (RBC) folate, serum cobalamin (Cbl), holo-transcobalamin (Holo-TC),

http://www.ncbi.nlm.nih.gov/pubmed?term=Cuenca-Garc%C3%ADa%20M%5BAuthor%5D&cauthor=true&cauthor_uid=23237548http://www.ncbi.nlm.nih.gov/pubmed?term=Cuenca-Garc%C3%ADa%20M%5BAuthor%5D&cauthor=true&cauthor_uid=23237548http://www.ncbi.nlm.nih.gov/pubmed?term=Ortega%20FB%5BAuthor%5D&cauthor=true&cauthor_uid=23237548http://www.ncbi.nlm.nih.gov/pubmed?term=Ortega%20FB%5BAuthor%5D&cauthor=true&cauthor_uid=23237548http://www.ncbi.nlm.nih.gov/pubmed?term=Ortega%20FB%5BAuthor%5D&cauthor=true&cauthor_uid=23237548http://www.ncbi.nlm.nih.gov/pubmed?term=Ruiz%20JR%5BAuthor%5D&cauthor=true&cauthor_uid=23237548http://www.ncbi.nlm.nih.gov/pubmed?term=Ruiz%20JR%5BAuthor%5D&cauthor=true&cauthor_uid=23237548http://www.ncbi.nlm.nih.gov/pubmed?term=Ruiz%20JR%5BAuthor%5D&cauthor=true&cauthor_uid=23237548http://www.ncbi.nlm.nih.gov/pubmed?term=Gonz%C3%A1lez-Gross%20M%5BAuthor%5D&cauthor=true&cauthor_uid=23237548http://www.ncbi.nlm.nih.gov/pubmed?term=Gonz%C3%A1lez-Gross%20M%5BAuthor%5D&cauthor=true&cauthor_uid=23237548http://www.ncbi.nlm.nih.gov/pubmed?term=Gonz%C3%A1lez-Gross%20M%5BAuthor%5D&cauthor=true&cauthor_uid=23237548http://www.ncbi.nlm.nih.gov/pubmed?term=Labayen%20I%5BAuthor%5D&cauthor=true&cauthor_uid=23237548http://www.ncbi.nlm.nih.gov/pubmed?term=Labayen%20I%5BAuthor%5D&cauthor=true&cauthor_uid=23237548http://www.ncbi.nlm.nih.gov/pubmed?term=Labayen%20I%5BAuthor%5D&cauthor=true&cauthor_uid=23237548http://www.ncbi.nlm.nih.gov/pubmed?term=Jago%20R%5BAuthor%5D&cauthor=true&cauthor_uid=23237548http://www.ncbi.nlm.nih.gov/pubmed?term=Jago%20R%5BAuthor%5D&cauthor=true&cauthor_uid=23237548http://www.ncbi.nlm.nih.gov/pubmed?term=Jago%20R%5BAuthor%5D&cauthor=true&cauthor_uid=23237548http://www.ncbi.nlm.nih.gov/pubmed?term=Mart%C3%ADnez-G%C3%B3mez%20D%5BAuthor%5D&cauthor=true&cauthor_uid=23237548http://www.ncbi.nlm.nih.gov/pubmed?term=Mart%C3%ADnez-G%C3%B3mez%20D%5BAuthor%5D&cauthor=true&cauthor_uid=23237548http://www.ncbi.nlm.nih.gov/pubmed?term=Mart%C3%ADnez-G%C3%B3mez%20D%5BAuthor%5D&cauthor=true&cauthor_uid=23237548http://www.ncbi.nlm.nih.gov/pubmed?term=Mart%C3%ADnez-G%C3%B3mez%20D%5BAuthor%5D&cauthor=true&cauthor_uid=23237548http://www.ncbi.nlm.nih.gov/pubmed?term=Dallongeville%20J%5BAuthor%5D&cauthor=true&cauthor_uid=23237548http://www.ncbi.nlm.nih.gov/pubmed?term=Dallongeville%20J%5BAuthor%5D&cauthor=true&cauthor_uid=23237548http://www.ncbi.nlm.nih.gov/pubmed?term=Dallongeville%20J%5BAuthor%5D&cauthor=true&cauthor_uid=23237548http://www.ncbi.nlm.nih.gov/pubmed?term=Bel-Serrat%20S%5BAuthor%5D&cauthor=true&cauthor_uid=23237548http://www.ncbi.nlm.nih.gov/pubmed?term=Bel-Serrat%20S%5BAuthor%5D&cauthor=true&cauthor_uid=23237548http://www.ncbi.nlm.nih.gov/pubmed?term=Bel-Serrat%20S%5BAuthor%5D&cauthor=true&cauthor_uid=23237548http://www.ncbi.nlm.nih.gov/pubmed?term=Marcos%20A%5BAuthor%5D&cauthor=true&cauthor_uid=23237548http://www.ncbi.nlm.nih.gov/pubmed?term=Marcos%20A%5BAuthor%5D&cauthor=true&cauthor_uid=23237548http://www.ncbi.nlm.nih.gov/pubmed?term=Marcos%20A%5BAuthor%5D&cauthor=true&cauthor_uid=23237548http://www.ncbi.nlm.nih.gov/pubmed?term=Manios%20Y%5BAuthor%5D&cauthor=true&cauthor_uid=23237548http://www.ncbi.nlm.nih.gov/pubmed?term=Manios%20Y%5BAuthor%5D&cauthor=true&cauthor_uid=23237548http://www.ncbi.nlm.nih.gov/pubmed?term=Manios%20Y%5BAuthor%5D&cauthor=true&cauthor_uid=23237548http://www.ncbi.nlm.nih.gov/pubmed?term=Breidenassel%20C%5BAuthor%5D&cauthor=true&cauthor_uid=23237548http://www.ncbi.nlm.nih.gov/pubmed?term=Breidenassel%20C%5BAuthor%5D&cauthor=true&cauthor_uid=23237548http://www.ncbi.nlm.nih.gov/pubmed?term=Breidenassel%20C%5BAuthor%5D&cauthor=true&cauthor_uid=23237548http://www.ncbi.nlm.nih.gov/pubmed?term=Widhalm%20K%5BAuthor%5D&cauthor=true&cauthor_uid=23237548http://www.ncbi.nlm.nih.gov/pubmed?term=Widhalm%20K%5BAuthor%5D&cauthor=true&cauthor_uid=23237548http://www.ncbi.nlm.nih.gov/pubmed?term=Widhalm%20K%5BAuthor%5D&cauthor=true&cauthor_uid=23237548http://www.ncbi.nlm.nih.gov/pubmed?term=Gottrand%20F%5BAuthor%5D&cauthor=true&cauthor_uid=23237548http://www.ncbi.nlm.nih.gov/pubmed?term=Gottrand%20F%5BAuthor%5D&cauthor=true&cauthor_uid=23237548http://www.ncbi.nlm.nih.gov/pubmed?term=Ferrari%20M%5BAuthor%5D&cauthor=true&cauthor_uid=23237548http://www.ncbi.nlm.nih.gov/pubmed?term=Ferrari%20M%5BAuthor%5D&cauthor=true&cauthor_uid=23237548http://www.ncbi.nlm.nih.gov/pubmed?term=Ferrari%20M%5BAuthor%5D&cauthor=true&cauthor_uid=23237548http://www.ncbi.nlm.nih.gov/pubmed?term=Kafatos%20A%5BAuthor%5D&cauthor=true&cauthor_uid=23237548http://www.ncbi.nlm.nih.gov/pubmed?term=Kafatos%20A%5BAuthor%5D&cauthor=true&cauthor_uid=23237548http://www.ncbi.nlm.nih.gov/pubmed?term=Kafatos%20A%5BAuthor%5D&cauthor=true&cauthor_uid=23237548http://www.ncbi.nlm.nih.gov/pubmed?term=Moln%C3%A1r%20D%5BAuthor%5D&cauthor=true&cauthor_uid=23237548http://www.ncbi.nlm.nih.gov/pubmed?term=Moln%C3%A1r%20D%5BAuthor%5D&cauthor=true&cauthor_uid=23237548http://www.ncbi.nlm.nih.gov/pubmed?term=Moln%C3%A1r%20D%5BAuthor%5D&cauthor=true&cauthor_uid=23237548http://www.ncbi.nlm.nih.gov/pubmed?term=Moreno%20LA%5BAuthor%5D&cauthor=true&cauthor_uid=23237548http://www.ncbi.nlm.nih.gov/pubmed?term=Moreno%20LA%5BAuthor%5D&cauthor=true&cauthor_uid=23237548http://www.ncbi.nlm.nih.gov/pubmed?term=Moreno%20LA%5BAuthor%5D&cauthor=true&cauthor_uid=23237548http://www.ncbi.nlm.nih.gov/pubmed?term=De%20Henauw%20S%5BAuthor%5D&cauthor=true&cauthor_uid=23237548http://www.ncbi.nlm.nih.gov/pubmed?term=De%20Henauw%20S%5BAuthor%5D&cauthor=true&cauthor_uid=23237548http://www.ncbi.nlm.nih.gov/pubmed?term=De%20Henauw%20S%5BAuthor%5D&cauthor=true&cauthor_uid=23237548http://www.ncbi.nlm.nih.gov/pubmed?term=Castillo%20MJ%5BAuthor%5D&cauthor=true&cauthor_uid=23237548http://www.ncbi.nlm.nih.gov/pubmed?term=Castillo%20MJ%5BAuthor%5D&cauthor=true&cauthor_uid=23237548http://www.ncbi.nlm.nih.gov/pubmed?term=Castillo%20MJ%5BAuthor%5D&cauthor=true&cauthor_uid=23237548http://www.ncbi.nlm.nih.gov/pubmed?term=Sj%C3%B6str%C3%B6m%20M%5BAuthor%5D&cauthor=true&cauthor_uid=23237548http://www.ncbi.nlm.nih.gov/pubmed?term=Sj%C3%B6str%C3%B6m%20M%5BAuthor%5D&cauthor=true&cauthor_uid=23237548http://www.ncbi.nlm.nih.gov/pubmed?term=Sj%C3%B6str%C3%B6m%20M%5BAuthor%5D&cauthor=true&cauthor_uid=23237548http://www.ncbi.nlm.nih.gov/pubmed?term=HELENA%20study%20group%5BCorporate%20Author%5Dhttp://www.ncbi.nlm.nih.gov/pubmed?term=HELENA%20study%20group%5BCorporate%20Author%5Dhttp://www.ncbi.nlm.nih.gov/pubmed?term=Gonz%C3%A1lez-Gross%20M%5BAuthor%5D&cauthor=true&cauthor_uid=23176792http://www.ncbi.nlm.nih.gov/pubmed?term=Gonz%C3%A1lez-Gross%20M%5BAuthor%5D&cauthor=true&cauthor_uid=23176792http://www.ncbi.nlm.nih.gov/pubmed?term=Benser%20J%5BAuthor%5D&cauthor=true&cauthor_uid=23176792http://www.ncbi.nlm.nih.gov/pubmed?term=Benser%20J%5BAuthor%5D&cauthor=true&cauthor_uid=23176792http://www.ncbi.nlm.nih.gov/pubmed?term=Benser%20J%5BAuthor%5D&cauthor=true&cauthor_uid=23176792http://www.ncbi.nlm.nih.gov/pubmed?term=Breidenassel%20C%5BAuthor%5D&cauthor=true&cauthor_uid=23176792http://www.ncbi.nlm.nih.gov/pubmed?term=Breidenassel%20C%5BAuthor%5D&cauthor=true&cauthor_uid=23176792http://www.ncbi.nlm.nih.gov/pubmed?term=Breidenassel%20C%5BAuthor%5D&cauthor=true&cauthor_uid=23176792http://www.ncbi.nlm.nih.gov/pubmed?term=Albers%20U%5BAuthor%5D&cauthor=true&cauthor_uid=23176792http://www.ncbi.nlm.nih.gov/pubmed?term=Albers%20U%5BAuthor%5D&cauthor=true&cauthor_uid=23176792http://www.ncbi.nlm.nih.gov/pubmed?term=Albers%20U%5BAuthor%5D&cauthor=true&cauthor_uid=23176792http://www.ncbi.nlm.nih.gov/pubmed?term=Huybrechts%20I%5BAuthor%5D&cauthor=true&cauthor_uid=23176792http://www.ncbi.nlm.nih.gov/pubmed?term=Huybrechts%20I%5BAuthor%5D&cauthor=true&cauthor_uid=23176792http://www.ncbi.nlm.nih.gov/pubmed?term=Huybrechts%20I%5BAuthor%5D&cauthor=true&cauthor_uid=23176792http://www.ncbi.nlm.nih.gov/pubmed?term=Valtue%C3%B1a%20J%5BAuthor%5D&cauthor=true&cauthor_uid=23176792http://www.ncbi.nlm.nih.gov/pubmed?term=Valtue%C3%B1a%20J%5BAuthor%5D&cauthor=true&cauthor_uid=23176792http://www.ncbi.nlm.nih.gov/pubmed?term=Valtue%C3%B1a%20J%5BAuthor%5D&cauthor=true&cauthor_uid=23176792http://www.ncbi.nlm.nih.gov/pubmed?term=Spinneker%20A%5BAuthor%5D&cauthor=true&cauthor_uid=23176792http://www.ncbi.nlm.nih.gov/pubmed?term=Spinneker%20A%5BAuthor%5D&cauthor=true&cauthor_uid=23176792http://www.ncbi.nlm.nih.gov/pubmed?term=Spinneker%20A%5BAuthor%5D&cauthor=true&cauthor_uid=23176792http://www.ncbi.nlm.nih.gov/pubmed?term=Segoviano%20M%5BAuthor%5D&cauthor=true&cauthor_uid=23176792http://www.ncbi.nlm.nih.gov/pubmed?term=Segoviano%20M%5BAuthor%5D&cauthor=true&cauthor_uid=23176792http://www.ncbi.nlm.nih.gov/pubmed?term=Widhalm%20K%5BAuthor%5D&cauthor=true&cauthor_uid=23176792http://www.ncbi.nlm.nih.gov/pubmed?term=Widhalm%20K%5BAuthor%5D&cauthor=true&cauthor_uid=23176792http://www.ncbi.nlm.nih.gov/pubmed?term=Widhalm%20K%5BAuthor%5D&cauthor=true&cauthor_uid=23176792http://www.ncbi.nlm.nih.gov/pubmed?term=Molnar%20D%5BAuthor%5D&cauthor=true&cauthor_uid=23176792http://www.ncbi.nlm.nih.gov/pubmed?term=Molnar%20D%5BAuthor%5D&cauthor=true&cauthor_uid=23176792http://www.ncbi.nlm.nih.gov/pubmed?term=Molnar%20D%5BAuthor%5D&cauthor=true&cauthor_uid=23176792http://www.ncbi.nlm.nih.gov/pubmed?term=Moreno%20LA%5BAuthor%5D&cauthor=true&cauthor_uid=23176792http://www.ncbi.nlm.nih.gov/pubmed?term=Moreno%20LA%5BAuthor%5D&cauthor=true&cauthor_uid=23176792http://www.ncbi.nlm.nih.gov/pubmed?term=Moreno%20LA%5BAuthor%5D&cauthor=true&cauthor_uid=23176792http://www.ncbi.nlm.nih.gov/pubmed?term=Stehle%20P%5BAuthor%5D&cauthor=true&cauthor_uid=23176792http://www.ncbi.nlm.nih.gov/pubmed?term=Stehle%20P%5BAuthor%5D&cauthor=true&cauthor_uid=23176792http://www.ncbi.nlm.nih.gov/pubmed?term=Stehle%20P%5BAuthor%5D&cauthor=true&cauthor_uid=23176792http://www.ncbi.nlm.nih.gov/pubmed?term=Pietrzik%20K%5BAuthor%5D&cauthor=true&cauthor_uid=23176792http://www.ncbi.nlm.nih.gov/pubmed?term=Pietrzik%20K%5BAuthor%5D&cauthor=true&cauthor_uid=23176792http://www.ncbi.nlm.nih.gov/pubmed?term=Pietrzik%20K%5BAuthor%5D&cauthor=true&cauthor_uid=23176792http://www.ncbi.nlm.nih.gov/pubmed?term=HELENA%20Study%20group%5BCorporate%20Author%5Dhttp://www.ncbi.nlm.nih.gov/pubmed?term=HELENA%20Study%20group%5BCorporate%20Author%5Dhttp://www.ncbi.nlm.nih.gov/pubmed?term=HELENA%20Study%20group%5BCorporate%20Author%5Dhttp://www.ncbi.nlm.nih.gov/pubmed?term=HELENA%20Study%20group%5BCorporate%20Author%5Dhttp://www.ncbi.nlm.nih.gov/pubmed?term=Pietrzik%20K%5BAuthor%5D&cauthor=true&cauthor_uid=23176792http://www.ncbi.nlm.nih.gov/pubmed?term=Stehle%20P%5BAuthor%5D&cauthor=true&cauthor_uid=23176792http://www.ncbi.nlm.nih.gov/pubmed?term=Moreno%20LA%5BAuthor%5D&cauthor=true&cauthor_uid=23176792http://www.ncbi.nlm.nih.gov/pubmed?term=Molnar%20D%5BAuthor%5D&cauthor=true&cauthor_uid=23176792http://www.ncbi.nlm.nih.gov/pubmed?term=Widhalm%20K%5BAuthor%5D&cauthor=true&cauthor_uid=23176792http://www.ncbi.nlm.nih.gov/pubmed?term=Segoviano%20M%5BAuthor%5D&cauthor=true&cauthor_uid=23176792http://www.ncbi.nlm.nih.gov/pubmed?term=Spinneker%20A%5BAuthor%5D&cauthor=true&cauthor_uid=23176792http://www.ncbi.nlm.nih.gov/pubmed?term=Valtue%C3%B1a%20J%5BAuthor%5D&cauthor=true&cauthor_uid=23176792http://www.ncbi.nlm.nih.gov/pubmed?term=Huybrechts%20I%5BAuthor%5D&cauthor=true&cauthor_uid=23176792http://www.ncbi.nlm.nih.gov/pubmed?term=Albers%20U%5BAuthor%5D&cauthor=true&cauthor_uid=23176792http://www.ncbi.nlm.nih.gov/pubmed?term=Breidenassel%20C%5BAuthor%5D&cauthor=true&cauthor_uid=23176792http://www.ncbi.nlm.nih.gov/pubmed?term=Benser%20J%5BAuthor%5D&cauthor=true&cauthor_uid=23176792http://www.ncbi.nlm.nih.gov/pubmed?term=Gonz%C3%A1lez-Gross%20M%5BAuthor%5D&cauthor=true&cauthor_uid=23176792http://www.ncbi.nlm.nih.gov/pubmed?term=HELENA%20study%20group%5BCorporate%20Author%5Dhttp://www.ncbi.nlm.nih.gov/pubmed?term=Sj%C3%B6str%C3%B6m%20M%5BAuthor%5D&cauthor=true&cauthor_uid=23237548http://www.ncbi.nlm.nih.gov/pubmed?term=Castillo%20MJ%5BAuthor%5D&cauthor=true&cauthor_uid=23237548http://www.ncbi.nlm.nih.gov/pubmed?term=De%20Henauw%20S%5BAuthor%5D&cauthor=true&cauthor_uid=23237548http://www.ncbi.nlm.nih.gov/pubmed?term=Moreno%20LA%5BAuthor%5D&cauthor=true&cauthor_uid=23237548http://www.ncbi.nlm.nih.gov/pubmed?term=Moln%C3%A1r%20D%5BAuthor%5D&cauthor=true&cauthor_uid=23237548http://www.ncbi.nlm.nih.gov/pubmed?term=Kafatos%20A%5BAuthor%5D&cauthor=true&cauthor_uid=23237548http://www.ncbi.nlm.nih.gov/pubmed?term=Ferrari%20M%5BAuthor%5D&cauthor=true&cauthor_uid=23237548http://www.ncbi.nlm.nih.gov/pubmed?term=Gottrand%20F%5BAuthor%5D&cauthor=true&cauthor_uid=23237548http://www.ncbi.nlm.nih.gov/pubmed?term=Widhalm%20K%5BAuthor%5D&cauthor=true&cauthor_uid=23237548http://www.ncbi.nlm.nih.gov/pubmed?term=Breidenassel%20C%5BAuthor%5D&cauthor=true&cauthor_uid=23237548http://www.ncbi.nlm.nih.gov/pubmed?term=Manios%20Y%5BAuthor%5D&cauthor=true&cauthor_uid=23237548http://www.ncbi.nlm.nih.gov/pubmed?term=Marcos%20A%5BAuthor%5D&cauthor=true&cauthor_uid=23237548http://www.ncbi.nlm.nih.gov/pubmed?term=Bel-Serrat%20S%5BAuthor%5D&cauthor=true&cauthor_uid=23237548http://www.ncbi.nlm.nih.gov/pubmed?term=Dallongeville%20J%5BAuthor%5D&cauthor=true&cauthor_uid=23237548http://www.ncbi.nlm.nih.gov/pubmed?term=Mart%C3%ADnez-G%C3%B3mez%20D%5BAuthor%5D&cauthor=true&cauthor_uid=23237548http://www.ncbi.nlm.nih.gov/pubmed?term=Mart%C3%ADnez-G%C3%B3mez%20D%5BAuthor%5D&cauthor=true&cauthor_uid=23237548http://www.ncbi.nlm.nih.gov/pubmed?term=Jago%20R%5BAuthor%5D&cauthor=true&cauthor_uid=23237548http://www.ncbi.nlm.nih.gov/pubmed?term=Labayen%20I%5BAuthor%5D&cauthor=true&cauthor_uid=23237548http://www.ncbi.nlm.nih.gov/pubmed?term=Gonz%C3%A1lez-Gross%20M%5BAuthor%5D&cauthor=true&cauthor_uid=23237548http://www.ncbi.nlm.nih.gov/pubmed?term=Ruiz%20JR%5BAuthor%5D&cauthor=true&cauthor_uid=23237548http://www.ncbi.nlm.nih.gov/pubmed?term=Ortega%20FB%5BAuthor%5D&cauthor=true&cauthor_uid=23237548http://www.ncbi.nlm.nih.gov/pubmed?term=Cuenca-Garc%C3%ADa%20M%5BAuthor%5D&cauthor=true&cauthor_uid=23237548

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Vitamin B(6) (PLP), and tHcy. The level of significance was set at P < .05. Following the currentcut-off for adults, 2% had low Cbl and 5% had low holo-TC concentrations. Low concentrationsof both PF and RBC folate were identified in 10%. Five percent had PLP concentrations

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observed for all cause mortality was equivalent to that for well established risk factors

such as elevated body mass index or blood pressure.

Longitudinal cardiorespiratory fitness algorithms for clinical

settings.Jackson AS,Sui X,O'Connor DP,Church TS,Lee DC,Artero EG,Blair SN.SourceDepartment of Health and Human Performance, University of Houston, Houston, Texas 77204-6015, USA. udde@mac.comAbstractBACKGROUND:Non-exercise algorithms are cost-effective methods to estimate cardiorespiratory fitness (CRF)in healthcare settings. The limitation of current non-exercise models is that they were developedwith cross-sectional data.PURPOSE:

To extend the non-exercise research by developing algorithms for men and women usinglongitudinal data on indicators available in healthcare settings.METHODS:The sample included 1325 women (aged 20-78 years) and 10,040 men (aged 20-86 years) whocompleted two to 21 maximal treadmill tests between 1977 and 2005. The data were analyzedin 2011 and 2012. The dependent variable was CRF measured by treadmill test. Theindependent variables were age; body composition (percentage fat or BMI); waistcircumference; self-reported physical activity; resting heart rate; and smoking behavior.RESULTS:

Linear mixed-models regression showed that all variables were independently related to CRF.There was a positive association between CRF and physical activity. Higher levels of bodycomposition were linked to lower CRF. High resting heart rate and smoking resulted in lowerestimates of CRF. The error estimates of the percentage fat algorithms were as follows: women,1.41 METs (95% CI=1.35, 1.47); and men, METs 1.54 (95% CI=1.51, 1.55). The BMI modelswere somewhat less accurate: women, METs 1.51 (95% CI=1.45, 1.58); and men, 1.66 METs(95% CI=1.63, 1.68).CONCLUSIONS:

These results showed that the CRF of women and men can be estimated from easily obtainedhealth indicators. The longitudinal non-exercise algorithms provide models to accuratelyestimate CRF changes associated with aging and provide cost-effective algorithms to track CRFover time with health indicators available in healthcare settings.Copyright 2012 American Journal of Preventive Medicine. Published by Elsevier Inc. All rightsreserved.

Ideal cardiovascular health and mortality: Aerobics CenterLongitudinal Study.

Artero EG,Espaa-Romero V,Lee DC,Sui X,Church TS,Lavie CJ,Blair SN.SourceDepartment of Exercise Science, Arnold School of Public Health, University of South Carolina,Columbia, SC 29208, USA. artero@ual.esAbstractOBJECTIVE:To analyze the relationship of ideal cardiovascular health to disease-specific death.PATIENTS AND METHODS:We used data from the Aerobics Center Longitudinal Study from October 9, 1987, to March 3,1999, to estimate the prevalence of ideal cardiovascular health in 11,993 individuals (24.3%women) and to examine its relationship with deaths from all causes, cardiovascular disease(CVD), and cancer.RESULTS:

During a mean follow-up of 11.6 years, 305 deaths occurred: 70 (23.0%) from CVD and 127(41.6%) from cancer. In the entire cohort, only 29 individuals (0.2%) had 7 ideal metrics. Afteradjusting for age, sex, examination year, alcohol intake, and parental history of CVD, risk of

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uthor%5D&cauthor=true&cauthor_uid=23079174http://www.ncbi.nlm.nih.gov/pubmed?term=Sui%20X%5BAuthor%5D&cauthor=true&cauthor_uid=23079174http://www.ncbi.nlm.nih.gov/pubmed?term=Jackson%20AS%5BAuthor%5D&cauthor=true&cauthor_uid=23079174

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death due to CVD was 55% lower in those participants who met 3 or 4 ideal metrics (hazardratio, 0.45; 95% confidence interval, 0.27-0.77) and 63% lower in those with 5 to 7 ideal metrics(hazard ratio, 0.37; 95% confidence interval, 0.15-0.95), compared with those who met 0 to 2ideal metrics. Although not significant, there was also a trend toward lower risk of death due toall causes across incremental numbers of ideal metrics. No association was observed fordeaths due to cancer.

CONCLUSION:The prevalence of ideal cardiovascular health was extremely low in a middle-aged cohort ofmen and women recruited between 1987 and 1999. The American Heart Association constructreflects well the subsequent risk of CVD, as reflected by graded CVD mortality in relation to thenumber of ideal metrics.Copyright 2012 Mayo Foundation for Medical Education and Research. Published by ElsevierInc. All rights reserved.http://www.ugr.es/~cts262/ES/articulos.html

Comparison of discriminative indices for iron deficiencyanemia and thalassemia trait in a Brazilian population.Matos JF, Dusse LM, Stubbert RV, Ferreira MR, Coura-Vital W, Fernandes AP, de Faria JR,Borges KB, Carvalho MD, Ramos AL.AbstractTo discriminate iron deficiency anemia (IDA) from thalassemia trait (TT), several indicesobtained from modern blood count analyzers have been reported. Discrimination power ofseven indices to differentiate between IDA and TT, such as Green and King Index (GKI), RDWIndex (RDWI), Srivastava Index (SRI), Mentzer Index (MI), Shine and Lal Index (SLI), EhsaniIndex (EI), and Sirdah Index (SI), were evaluated. These indices were applied on 47 patientswith TT and on 289 patients with IDA, as confirmed by gold standard tests. Sensitivity,specificity, positive and negative predictive values, efficiency, area under receiver-operatingcharacteristics curve (AUC), and Youden's Index (YI) were calculated. GKI and RDWI showed

the highest reliability, as they had the largest AUCs (0.919, 0.912, respectively) and Youden'sIndex (70.4, 74.6, respectively). Conversely, SLI presented a less satisfactory performance(AUC = 0.786 and YI = 6.6). Data taken together suggest the superiority of GKI and RDWI todiscriminate between IDA and TT.

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