ascoril expectorant - faq's

8/13/2019 Ascoril Expectorant - FAQ's

http://slidepdf.com/reader/full/ascoril-expectorant-faqs 1/16

1st Rational & Complete Expectorant

No.1 Prescribed Brand as per Cmarc in India

Only Expectorant backed by Clinical Trials

Only Expectorant backed by 25 years of Clinical

Experience

Offers the right pH of 3.7 to 3.9 for better absorption of

Bromhexine & Guaifenesin



Offers right viscosity for better contact to the irritated

mucosa Non - Sedating Expectorant

Easy to recall ( AS – Assured, CO – Cough, RIL – Reliever)

Sugar content is only 2.45 gm / 5 ml, equivalent to approx 10

calories. (i.e.10 ml 3 times daily, would result in additional 60

calories/day.) Hence, can be prescribed in diabetic patients.

Highly palatable due to Mixed Fruit Flavour with a

transparent color coded measuring cup

Available in Unbreakable Pet bottle with Golden Cap &

Original Hologram



BROZEDEX - Wockhardt

ZEET - Alembic

PIRITON - GSK

DILOSYN - GSK

BROZEET - Alembic TUSPEL - PLUS - Indoco



BROZEDEX - WOCKHARDT

Composition in Each 5 ml

Terbutaline sulphate 1.25mgBromhexine Hcl 4mg

Guaifenesin 50mg

Menthol 2.5mg

High Concentration of Bromhexine can cause gastric irritation, nausea,

vomiting, epigastric pain & diarrhoea .( as monotherapy 4-8mg 3-4 times /day is

recommended). Skin rashes are rare & is used with precaution in peptic ulcer.

Can give unpleasant taste.

Concentration of Menthol is high

Transparent bottle, hence not protected by Sunlight



ZEET EXPECTORANT - ALEMBIC Composition in Each 5 mlDiphenhydramine Hcl 8mg

Guaiphenesin 50mg

Bromhexine Hcl 4mgAmmonium Chloride 100mg

Menthol 1mg

High Concentration of Bromhexine can cause gastric irritation, nausea,

vomiting, epigastric pain & diarrhoea .( as monotherapy 4-8mg 3-4 times is

recommended) Skin rashes are rare & is used with precaution in peptic ulcer.Can give unpleasant taste.

Diphenhydramine ,being antihistamine can cause drowsiness & drying effect of

mucus to delay expectoration. Hence is not rational for Productive cough.

Use of two expectorant is not justified & does not provide a bronchodilator to easebronchospasm to facilitate normal breathing.



PRITON EXPECTORANT - GSK

Composition in Each 5 mlChlorpheniramine Maleate 2.5mg

Ammonium Chloride 125mg

Sodium Citrate 55 mg

Does not provide a Bronchodilator & Mucolytic / Mucokinetic for easy expectoration

Chlorpheniramine maleate, being antihistamine can cause drowsiness & drying

effect of mucus to delay expectoration. Hence is not rational for Productive cough.

Use of two outdated saline expectorant is not justified



DILOSYN EXPECTORANT - GSK

Composition in Each 5 mlMethdilazine Hcl 2.5mg


Sodium Citrate 50 mg

Menthol 0.25 mg

Does not provide a Bronchodilator & Mucolytic / Mucokinetic for easy expectoration

Methdilazine Hcl, being antihistamine can cause drowsiness & drying

effect of mucus to delay expectoration. Hence is not rational for Productive cough.

Use of two outdated saline expectorant is not justified,Guaifenesin is a better

expectorant



NEW BROZEET EXPECTORANT - ALEMBIC

Composition in Each 5 mlTerbutaline Sulphate 1.5 mg

Ambroxol 15 mg

Guaifenesin 50 mg

Ambroxol is the 7th metabolite of Bromhexine HCl, has similar properties of

Bromhexine HCl.



TUSPEL PLUS - INDOCO

Composition in Each 5 mlTerbutaline sulphate 1.25mg

Bromhexine Hcl 4mg


Menthol 0.75mg

Contains outdated salt expectorant instead of widely accepted

expectorant Guaifenesin

Guaifenesin works by drawing water into the bronchi. The water both thins mucus

& lubricates the airway, facilitating removal of mucus by coughing.



Terbutaline in Ascoril Expectorant causes tremors in patients ?

Doctor, I understand your concern about tremors with Terbutaline

Doctor, Fine muscular tremors are very common & are less serious side effects

seen with Terbutaline & Salbutamol (albuterol)

Both Terbutaline & Salbutamol belong to short acting Bronchodilator (Beta 2 agonist )

Adverse effects, like tremors & tachycardia may occur more frequently with

terbutaline. Hence, proper monitoring is needed. Tolerance to this effect can be

expected within 1-2 weeks or chronic therapy

Adverse CNS or musculoskeletal effects (nervousness, headache, hand tremor) with

albuterol (41%) terbutaline (73%), While with I.V. albuterol had a higher incidence

of palpitations (14/20) than either terbutaline (7/20).

Proper dosing with transparent color coded measuring cup can avoid &

minimise these side effects. At therapeutic dose Terbutaline is safe & well tolerated.



Your Ascoril Expectorant is very common as it is sold over the

counter

Doctor, you are right in saying that Ascoril Expectorant is sometimes sold over the

counter, this is because it is the No.1 prescribed Expectorant brand in India, hence

is purchased as a follow-up treatment.

Doctor, we were the first to launch Ascoril Expectorant as rationale & complete

expectorant for Productive cough, hence is known for good relief from congestion.

Therefore, in Productive Cough, patients continue to buy to get relief from Productive

Cough, Mucus Hypersecretion in Chronic Bronchitis & from Bronchospasm.

Doctor let me add that we may be No.1 in the country & in some countries abroad, butto be No.1 in this territory we want your prescription support without which we are

nothing. Moreover, doctor would you not like to associate your prescription with India’s

No.1 brand - Ascoril Expectorant.

Emotive approach and raising the ego of the doctor will be very important to get

his prescription support.



I cannot prescribe Ascoril Expectorant to a diabetic

patient ?

Doctor, I understand your concern about your diabetic patient. Hence, Glenmark

keeping in mind these diabetics, provides a sugar content of only

2.45 gm/ 5 ml, that is equivalent to approx 10 calories in Ascoril Expectorant.

(i.e.10 ml 3 times daily, would result in additional 60 calories/day.)Hence, should not be a problem in prescribing Ascoril Expectorant in a diabetic

patients.

As the sugar content is low, the above details if confidently conveyed to the doctor

should create a positive response.



Your Ascoril expectorant is a costly preparation ascompared to other Salbutamol brands ?

Doctor, you are well informed that Salbutamol brands are priced less compared to

Terbutaline brands. This is mainly because of the pricing policy. But doctor carefullynotice that these brands have either a combination of Salbutamol with

Bromhexine/Ambroxol or Salbutamol with Guaifenesin. This means these brands

either miss the vital Mucolytic/Mucokinetic or an Expectorant. That means these

brands compromise on the efficacy i.e. Complete expectoration.

Therefore, do you think without Bromhexine or Guaifenesin can there be a complete

expectoration.

If the above doctor is a Pediatrician introduce Ascoril-LS stating the benefits of Levo-

Salbutamol vis-à-vis Salbutamol and also give the benefits of Ambroxol.



Your Bromhexine concentration in Ascoril

Expectorant is very less compared to other brands ? High Concentration of Bromhexine can cause gastric irritation, nausea,

vomiting, epigastric pain & diarrhoea .( as monotherapy 4-8mg 3-4 times /day

is recommended). Skin rashes are rare & is used with precaution in peptic

ulcer being a mucolytic. Can give unpleasant taste in higher concentration.

Doctor, with Ascoril Expectorant as per the specified dosage a pediatric patientgets Bromhexine 6-8mg /day if Ascoril Expectorant is given 5 ml 3-4 times daily

and an adult patient gets approx. 12-16mg /day. This concentration is well

tolerated and does not affect the taste of Ascoril Expectorant.

As Bromhexine is given along with Guaifenesin it works by drawing water

into the bronchi. The water both thins mucus & lubricates the airway, facilitatingremoval of mucus by coughing. Hence in combination gives better results.

The above information should be confidently put forward to the doctor. Doctor, if

Bromhexine was less Ascoril Expectorant would have not become No.1 in India.

Doctor kindly judge Ascoril Expectorant by its efficacy and not by what others are

saying. In case you are treating a chronic adult patient you also have Ascoril tabletwith 8mg Bromhexine



Bromhexine in Ascoril Expectorant is outdated, youshould replace with Ambroxol ?

Doctor you are absolutely right in saying that Ambroxol is latest than Bromhexine.

Moreover, you will agree that Ambroxol is the 7 th active metabolite of Bromhexine.

Hence, Doctor most of the properties you will agree of Ambroxol are similar to

Bromhexine and both these preparations are ideal for acute respiratory conditions.

Doctor,Ascoril Expectorant being launched first has Bromhexine while the latest

launch of our prestigious product Ascoril-LS has Ambroxol .We from Glenmark offer

you the best of both.



Terbutaline is not preferred in pediatric age group ?

Doctor ,as per text books, Terbutaline is recommended in children above 6yrs.,while

Albuterol is recommended in children above 2yrs.

But studies show that with Terbutaline oral dose of 0.75 milligram to 1.5 milligrams

twice or three times daily has been recommended for children 3 to 7 years of age.

For children 7 to 15 years of age, an oral dose of 1.5 to 3 milligrams twice or three times

daily has been suggested (Brogden et al, 1973a).

The dosage of terbutaline should be based upon body weight(Leegaard & Fjulsrug, 1973). A dose of 0.075 milligram/kilogram resulted in marked

bronchodilation in asthmatic children. This effect was maintained for over 5 hours.

Doctor, as per the above data we request you to prescribe Ascoril Expectorant in

Pediatric age group.

ascoril expectorant - faq's

Documents