bacterial vaginosis (bv) and vulvovaginal causes of ...€¦ · bacterial vaginosis (bv) and...
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1. Imhof_IntJGynecolObstetr05_89-1272. Vladareanu_EurRevMedPharmacolSci18_22-2623. Russo_ArGynecolObstetrics18_298-1394. DeAlberti_ArchGynecolObstet15_292-861
5. Morelli_JClinGastroenterol04_38-S1076. Murina_JClinGastroenterol14_487. Vicariotto_JClinGastroenterol12_46-S738. Mogna_JClinGastroenterol12_46-S29
9. Vicariotto_JClinGastroenterol14_48-S9610. Vicariotto_JClinGastroenterol14_48-S10611. Tobaldini-Valerio_FutureMicrobiol16_11-103512. Pasupuleti_OxidMedCelLongevity17-1259510
13. DaCostaRocha_FoodChem14_165-42414. Jung_JSciFoodAgric13_93-376915. Scientific Opinion_EFSAJ10_8-175416. Consenso sobre uso de los probióticos en ginecología. SEPyP
UNIQUE COMPOSITION FOR ORAL INTAKE EFFECTIVITY
70-75% OF WOMEN
will experience at least oneepisode of vaginitis during
their lives, and 40% to 50%of them will experience
recurrent infection.
Lactobacilli represent almost 90% of vaginal microbiota of healthy women. Vaginal infections are characterized by a significant decrease in vaginal lactobacilli, which are associa-ted with an overgrowth of pathogens such as Candida spp2.
Several studies revealed that oral intake of lactobacilli results in significantly increased vaginal colonization of lactobacilli via migration from the gastrointestinal tract to the vagina2,3,4,5.
THE ULTIMATE SOLUTIONFOR VAGINAL HEALTH!BACTERIAL VAGINOSIS (BV) AND VULVOVAGINAL CANDIDIASIS (VVC) ARE THE MOST PREVALENT CAUSES OF SYMPTOMATIC VAGINITIS1.
HIBISCUS
PROPOLIS
LACTOBACILLUS
VITAMIN A
• A selected combination of clinically supported probiotic strains in BV and VVC (Lactobacillus acido- philus and Lactobacillus plantarum) and in vitro studies against Candida spp. E. coli, etc.6, 7, 8, 9, 10 and Lactobaci-llus crispatus, one of the most common species present in vaginal microbiota of healthy women2.
• Propolis, a natural complex compound based on polyphenols and other active substances. Several studies demonstrated that propolis is an antifungal agent with effect on Candida spp. and inhibition of biofilm formation1, 11, 12.
• Hibiscus (Hibiscus sabdariffa L.), that has demonstrated to be a great antimicrobial agent against different pathogen microorganism includingE. coli, involved in UTIs13, 14.
• Vitamin A that contributes to the maintenance of mucous membranes and contributes to the normal functioning of the immune system, also in the vaginal mucosa15 (EFSA authorised health claims).
GINIWA CONTAINS:
WE ARE LOOKING FOR YOU
We are looking for a partner with a strong presence in the women’s health sector and with interest in comple-
menting its portfolio of health care products with this unique and high quality product for gynaecology.
YOUROPPORTUNITYWe offer a unique product for women health, manufactured at our GMP facili-ties. Giniwa is an oral probiotic supple-ment in capsules. Product is available for license in different countries and approved in the UE as a food supplement.
Zinereo Pharma is open to commercially develop its projects by means of sound partnerships, license agreements and win/win Strategic Alliances in a variety of geographies, focusing on potential partners interested in rights for a wide
region or territory.
Bialactis Biotech and Zinereo Pharma are companies of Zendal Group. Zinereo Pharma is a fast growing biotech Spanish group devoted to the R&D development of innovative, differentiated and/or IP supported probiotic strains useful for a variety of health conditions. Having a Pharma DNA, Zinereo Pharma enjoys, formulation and finished forms production capabilities, working under GMP conditions.
Copyright Zinereo Pharma , S.L.U. 2019. This document is strictly private, confidential and personal to its recipients.
GINIWA IS A NEW ORAL FORMULATIONof lactobacilli, propolis, hibiscus and vitamin A
for reinforce and maintain the vaginal andurogenital microbiota in women.
GINIWA IS A FOOD SUPPLEMENTIt gives you the opportunity to offer an innovative concept to the market, keeping away of legal restriction for vaginal probiotics standard treatments and differentiated
to vaginal capsules, ovules or any other medical device.
LACTOBACILLI MIGRATE EFFICIENTLYfrom the digestive tract to the vaginal and urinary environment to exert their function against infections2,3,4,5,16.
NEW CONCEPT
REINFORCE YOUR VAGINAL &UROGENITAL MICROBIOTA VIA ORAL INTAKE
[email protected] www.zinereopharma.com Tel + 34 986 345 200
1. Imhof_IntJGynecolObstetr05_89-1272. Vladareanu_EurRevMedPharmacolSci18_22-2623. Russo_ArGynecolObstetrics18_298-1394. DeAlberti_ArchGynecolObstet15_292-861
5. Morelli_JClinGastroenterol04_38-S1076. Murina_JClinGastroenterol14_487. Vicariotto_JClinGastroenterol12_46-S738. Mogna_JClinGastroenterol12_46-S29
9. Vicariotto_JClinGastroenterol14_48-S9610. Vicariotto_JClinGastroenterol14_48-S10611. Tobaldini-Valerio_FutureMicrobiol16_11-103512. Pasupuleti_OxidMedCelLongevity17-1259510
13. DaCostaRocha_FoodChem14_165-42414. Jung_JSciFoodAgric13_93-376915. Scientific Opinion_EFSAJ10_8-175416. Consenso sobre uso de los probióticos en ginecología. SEPyP
UNIQUE COMPOSITION FOR ORAL INTAKE EFFECTIVITY
70-75% OF WOMEN
will experience at least oneepisode of vaginitis during
their lives, and 40% to 50%of them will experience
recurrent infection.
Lactobacilli represent almost 90% of vaginal microbiota of healthy women. Vaginal infections are characterized by a significant decrease in vaginal lactobacilli, which are associa-ted with an overgrowth of pathogens such as Candida spp2.
Several studies revealed that oral intake of lactobacilli results in significantly increased vaginal colonization of lactobacilli via migration from the gastrointestinal tract to the vagina2,3,4,5.
THE ULTIMATE SOLUTIONFOR VAGINAL HEALTH!BACTERIAL VAGINOSIS (BV) AND VULVOVAGINAL CANDIDIASIS (VVC) ARE THE MOST PREVALENT CAUSES OF SYMPTOMATIC VAGINITIS1.
HIBISCUS
PROPOLIS
LACTOBACILLUS
VITAMIN A
• A selected combination of clinically supported probiotic strains in BV and VVC (Lactobacillus acido- philus and Lactobacillus plantarum) and in vitro studies against Candida spp. E. coli, etc.6, 7, 8, 9, 10 and Lactobaci-llus crispatus, one of the most common species present in vaginal microbiota of healthy women2.
• Propolis, a natural complex compound based on polyphenols and other active substances. Several studies demonstrated that propolis is an antifungal agent with effect on Candida spp. and inhibition of biofilm formation1, 11, 12.
• Hibiscus (Hibiscus sabdariffa L.), that has demonstrated to be a great antimicrobial agent against different pathogen microorganism includingE. coli, involved in UTIs13, 14.
• Vitamin A that contributes to the maintenance of mucous membranes and contributes to the normal functioning of the immune system, also in the vaginal mucosa15 (EFSA authorised health claims).
GINIWA CONTAINS:
WE ARE LOOKING FOR YOU
We are looking for a partner with a strong presence in the women’s health sector and with interest in comple-
menting its portfolio of health care products with this unique and high quality product for gynaecology.
YOUROPPORTUNITYWe offer a unique product for women health, manufactured at our GMP facili-ties. Giniwa is an oral probiotic supple-ment in capsules. Product is available for license in different countries and approved in the UE as a food supplement.
Zinereo Pharma is open to commercially develop its projects by means of sound partnerships, license agreements and win/win Strategic Alliances in a variety of geographies, focusing on potential partners interested in rights for a wide
region or territory.
Bialactis Biotech and Zinereo Pharma are companies of Zendal Group. Zinereo Pharma is a fast growing biotech Spanish group devoted to the R&D development of innovative, differentiated and/or IP supported probiotic strains useful for a variety of health conditions. Having a Pharma DNA, Zinereo Pharma enjoys, formulation and finished forms production capabilities, working under GMP conditions.
Copyright Zinereo Pharma , S.L.U. 2019. This document is strictly private, confidential and personal to its recipients.
GINIWA IS A NEW ORAL FORMULATIONof lactobacilli, propolis, hibiscus and vitamin A
for reinforce and maintain the vaginal andurogenital microbiota in women.
GINIWA IS A FOOD SUPPLEMENTIt gives you the opportunity to offer an innovative concept to the market, keeping away of legal restriction for vaginal probiotics standard treatments and differentiated
to vaginal capsules, ovules or any other medical device.
LACTOBACILLI MIGRATE EFFICIENTLYfrom the digestive tract to the vaginal and urinary environment to exert their function against infections2,3,4,5,16.
NEW CONCEPT
REINFORCE YOUR VAGINAL &UROGENITAL MICROBIOTA VIA ORAL INTAKE
[email protected] www.zinereopharma.com Tel + 34 986 345 200