Big data and the promise of personalized medicine

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Big data and the promise of personalized medicine. Indrek Vainu Helsinki Business Hub indrek.vainu@helsinkibusinesshub.fi Mobile: +358 44 746 3902. Hello!. What is Personalized Medicine?. Customization of healthcare decisions, practices, products tailored to individual patients. - PowerPoint PPT Presentation

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  • Big data and the promise of personalized medicineIndrek VainuHelsinki Business Hub

    indrek.vainu@helsinkibusinesshub.fiMobile: +358 44 746 3902

  • Hello!

  • What is Personalized Medicine?

    Customization of healthcare decisions, practices, products tailored to individual patients

  • A lot of dataThe source code of you => 3.2 billion base pairsSequenced => 700 MB of datahttp://cdn.trendhunterstatic.com/thumbs/illumina-hiseq-2500.jpeghttp://thewinnower.com/blog/rejected-pt-1/

  • Beating Moores lawhttp://www.genome.gov/images/content/cost_per_genome_apr.jpg

  • Biobanks + data centershttp://www.ebo-enterprises.com/sites/default/files/images/07-14datacenter_lg.jpg

  • Genomics ROI

    Every dollar we invested to map the human genome returned $140 to our economy.--President Barack Obama, 2013 State of the Union address, Feb. 12, 2013http://web.ornl.gov/sci/techresources/Human_Genome/publicat/BattelleReport2011.pdf

  • In the news

  • The promise?http://www.condenaststore.com/-sp/Here-s-to-the-human-genome-and-its-potential-in-finding-at-long-last-a-Cartoon-Prints_i8643225_.htm

  • The basis for personalized medicine

  • BenefitsGenetic testing to select drugsXalkori, non-small cell lung cancer drugTreatment cost $10,000 / monthWorks only for ALK-positive gene mutation patients (3-5%)Testing costs $40024 out of 25 patients do not respondBOTTOM LINE => testing all $10,000 vs $250,000/monthCategorized treatment plansIdentifying responding patientshttp://abcnews.go.com/Health/CancerPreventionAndTreatment/lung-cancer-pill-crizotinib-highlights-improved-iding-treating/story?id=14414833

  • Finland well positionedFinland has:several biobanksunique genomic compositionelectronic medical recordsresearch infrastructure

    Recently:Biobank Act to use biobank data for research purposes

  • Thank you

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