7/25/2019 bio376 - 2-3-16 (lecture)

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2-3-16 Biochem class (important for mechanisms later on in the course)

acetic acid (ethanoic acid)

pyruvate acid (pyruvate is o- on OH) ******

Tautomeriation

(enol form of pyruvate is -OH ! "O! -O )

#hosphoenolpyruvate is $O-H#O3! "O! -O

%&'#

Oaloacetate acid is made from acetic acid and pyruvate

icar+oylic acid (O,.#)/ (0-mneumonic)https/eni4ipediaor5i4iicar+oylicacid78inearsaturateddicar+oylicacids

- Oalic acid (no 'H29s in +eteen '"O9s)

- ,alonic acid (one 'H29s in +eteen '"O9s)

- uccinic acid (to 'H29s in +eteen '"O9s)

- .lutaric acid (three 'H29s in +eteen '"O9s)

- dipic acid (four 'H29s in +eteen '"O9s)- #imelic acid (:ve 'H29s in +eteen '"O9s)

Bicar+onate is a +u;er than ill

7/25/2019 bio376 - 2-3-16 (lecture)

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tructure of lactate/

(+asically a reduced form of pyruvate)

8H is lactate dehydro5enase

7/25/2019 bio376 - 2-3-16 (lecture)

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#yrimidinesC later on

?hich hydride is involved in