such as medicine, en-

gineering, and fi-

nance, that few could

master alone. This is

the main reason why

many innovative

ideas fail before

reaching the market.

Therefore, there is a

need for a truly multi

-disciplinary team-

based course that

focuses on medical

innovation.

The last decade has

seen an exponential

growth in scientific and

medical knowledge,

coupled with an in-

creasingly complex

technology. Regretfully,

health care costs have

been rapidly increasing

over the same time

period. It is hoped that

medical innovation

would drive a more

efficient and cost effec-

tive health care sys-

tem. However, the

process of creating

new, cost-effective

medical devices re-

quires an in-depth

understanding of

multiple disciplines

Bio-Design a cure

The Biodesign innovation process is structured process to develop new medical

technologies. It has been developed to help both amateur and experienced

innovators to reduce their risk of failure. This process was developed in

Stanford University’s Program called Biodesign and serves as the foundation to

the text book Biodesign: The Process of Innovating Medical Technologies.

BioAura

Inside this issue:

Page 2– Kick of Zika

Page 3– Departmental

Activities

Page 4- Fun Zone

8

September 2016 Departmental

Principals Message

It is a matter of great pleas-

ure to see the creative con-

tribution of the students to

this newsletter. Bioaura

gives a platform for the

students to share latest

knowledge and to keep

pace with the current de-

velopments in this field. I

congratulate the dedicated

team of staff and students

who have contributed. My

best wishes and blessings

for all he endeavors of the

department.

Rev. Dr. G.Vazhan Arasu

HODs Message

It gives me great pleasure

to pen few words of en-

couragement for the de-

partmental newsletter. The

theme of the newsletter is

‘ S m a r t C i t y a n d

Biodesign’, which is the

current initiative of the

Government of India. I am

sure that through this news-

letter the readers would get

a bird’s eye view of the

concept of smart city and

biodesign. Best wishes and

good luck.

Dr. S. Buvaneswari

Zika virus is a mosquito-borne flavivirus that was first identified in Uganda in 1947 in monkeys through a network that monitored yellow fever. It was later identified in humans in 1952 in Uganda and the United Republic of Tanzania. Outbreaks of Zika virus disease have been recorded in Africa, America, Asia and the Pacific. From the 1960s to 1980s, human infections were found across Africa and Asia, typically accompanied by mild illness.

The Kick of Zika

Page 2 BioAura

Sneha Mohanan and Uday Bahadur Singh — M.Sc III SEM

FAST FACTS The majority of people in-

fected with Zika virus do not display any symptoms.

Cases of Zika virus infection that result in hospitalization are uncommon.

A link between maternal Zika infection and infant micro-cephaly is currently being investigated.

As yet, there is not enough evidence to fully characterize the link between the two conditions.

Zika infection can spread from a mother to a fetus dur-ing pregnancy.

At present, there is no treat-ment for the virus.

Zika From the Cartoonist’s Pen

Endophytic fungi isolated from neem leaves are reported in this investigation. The present study showed the existence of endophytic fungi in neem leaves and it can be of great importance if further studies are conducted to isolate bioactive secondary metabolites and their medicinal properties can be studied. Two fungal species have been isolated Fusarium oxysporum and Alternaria from three sets of observations on PDA plates. Identification is currently based on the morphological and staining characteristics. The efficacy of neem leaves was done against its own endophytic fungus

Fusarium oxysporum (leaf extract at different concentrations was taken for study. A significant reduction in growth of mycelium has been observed by increasing the concentration of leaf ex-tract against Fusarium oxysporum. The efficacy of neem leaf extract has been found to be very effective against test fungus (Fusarium). Further analysis of all concentration variants however showed net per-centage inhibition, it was AzPDA 100 shows maximum 30.90%.net percentage mycelial growth inhibition, while AzPDA 20 show 47.27% net percentage inhibition.

Isolation of Endophytic Fungus From Neem Leaves and Efficacy of neem leaf extract against its own isolated fungal endophytes.

A.NEEM LEAF (SAMPLE) B.FUNGAL ENDOPHYTES C.PERCENTAGE INHIBITION OF MYCELIUM GROWTH

Keywords: Fusarium oxysporum, AzPDA, Azadirachta indica

Departmental Research at a Glance Page 3

Radial growth measurement (in cm) after 7 days of incubation

Diameter (Cm) Percentage inhibition of mycelia growth

%=100*CD-TD/CD

Control 5.5

A2 PDA 20 2.9 47.27%

A2 PDA 40 3.2 41.81%

A2 PDA 60 3.5 36.36%

A2 PDA 80 3.6 34.54%

A2 PDA 100 3.8 30.90%

The efficacy of neem leaves extract is found very effective against test fungus Fusarium by increasing the concentration of the

leaf extract the growth of mycelia decreased.

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