such as medicine, en-
gineering, and fi-
nance, that few could
master alone. This is
the main reason why
many innovative
ideas fail before
reaching the market.
Therefore, there is a
need for a truly multi
-disciplinary team-
based course that
focuses on medical
innovation.
The last decade has
seen an exponential
growth in scientific and
medical knowledge,
coupled with an in-
creasingly complex
technology. Regretfully,
health care costs have
been rapidly increasing
over the same time
period. It is hoped that
medical innovation
would drive a more
efficient and cost effec-
tive health care sys-
tem. However, the
process of creating
new, cost-effective
medical devices re-
quires an in-depth
understanding of
multiple disciplines
Bio-Design a cure
The Biodesign innovation process is structured process to develop new medical
technologies. It has been developed to help both amateur and experienced
innovators to reduce their risk of failure. This process was developed in
Stanford University’s Program called Biodesign and serves as the foundation to
the text book Biodesign: The Process of Innovating Medical Technologies.
BioAura
Inside this issue:
Page 2– Kick of Zika
Page 3– Departmental
Activities
Page 4- Fun Zone
8
September 2016 Departmental
Principals Message
It is a matter of great pleas-
ure to see the creative con-
tribution of the students to
this newsletter. Bioaura
gives a platform for the
students to share latest
knowledge and to keep
pace with the current de-
velopments in this field. I
congratulate the dedicated
team of staff and students
who have contributed. My
best wishes and blessings
for all he endeavors of the
department.
Rev. Dr. G.Vazhan Arasu
HODs Message
It gives me great pleasure
to pen few words of en-
couragement for the de-
partmental newsletter. The
theme of the newsletter is
‘ S m a r t C i t y a n d
Biodesign’, which is the
current initiative of the
Government of India. I am
sure that through this news-
letter the readers would get
a bird’s eye view of the
concept of smart city and
biodesign. Best wishes and
good luck.
Dr. S. Buvaneswari
Zika virus is a mosquito-borne flavivirus that was first identified in Uganda in 1947 in monkeys through a network that monitored yellow fever. It was later identified in humans in 1952 in Uganda and the United Republic of Tanzania. Outbreaks of Zika virus disease have been recorded in Africa, America, Asia and the Pacific. From the 1960s to 1980s, human infections were found across Africa and Asia, typically accompanied by mild illness.
The Kick of Zika
Page 2 BioAura
Sneha Mohanan and Uday Bahadur Singh — M.Sc III SEM
FAST FACTS The majority of people in-
fected with Zika virus do not display any symptoms.
Cases of Zika virus infection that result in hospitalization are uncommon.
A link between maternal Zika infection and infant micro-cephaly is currently being investigated.
As yet, there is not enough evidence to fully characterize the link between the two conditions.
Zika infection can spread from a mother to a fetus dur-ing pregnancy.
At present, there is no treat-ment for the virus.
Zika From the Cartoonist’s Pen
Endophytic fungi isolated from neem leaves are reported in this investigation. The present study showed the existence of endophytic fungi in neem leaves and it can be of great importance if further studies are conducted to isolate bioactive secondary metabolites and their medicinal properties can be studied. Two fungal species have been isolated Fusarium oxysporum and Alternaria from three sets of observations on PDA plates. Identification is currently based on the morphological and staining characteristics. The efficacy of neem leaves was done against its own endophytic fungus
Fusarium oxysporum (leaf extract at different concentrations was taken for study. A significant reduction in growth of mycelium has been observed by increasing the concentration of leaf ex-tract against Fusarium oxysporum. The efficacy of neem leaf extract has been found to be very effective against test fungus (Fusarium). Further analysis of all concentration variants however showed net per-centage inhibition, it was AzPDA 100 shows maximum 30.90%.net percentage mycelial growth inhibition, while AzPDA 20 show 47.27% net percentage inhibition.
Isolation of Endophytic Fungus From Neem Leaves and Efficacy of neem leaf extract against its own isolated fungal endophytes.
A.NEEM LEAF (SAMPLE) B.FUNGAL ENDOPHYTES C.PERCENTAGE INHIBITION OF MYCELIUM GROWTH
Keywords: Fusarium oxysporum, AzPDA, Azadirachta indica
Departmental Research at a Glance Page 3
Radial growth measurement (in cm) after 7 days of incubation
Diameter (Cm) Percentage inhibition of mycelia growth
%=100*CD-TD/CD
Control 5.5
A2 PDA 20 2.9 47.27%
A2 PDA 40 3.2 41.81%
A2 PDA 60 3.5 36.36%
A2 PDA 80 3.6 34.54%
A2 PDA 100 3.8 30.90%
The efficacy of neem leaves extract is found very effective against test fungus Fusarium by increasing the concentration of the
leaf extract the growth of mycelia decreased.
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