biosintesi delle catecolamine
DESCRIPTION
BIOSINTESI DELLE CATECOLAMINE. AZIONI PERIFERICHE DELLA DOPAMINA. Recettori D1 (distretti vascolari renale, mesenterico e coronarico). Vasodilatazione; RBF, GFR e secrezione di Na+. Recettori 1 (cardiaci). Effetto inotropo e cronotropo +. MALATTIA DI PARKINSON. Segni cardinali - PowerPoint PPT PresentationTRANSCRIPT
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BIOSINTESI DELLE CATECOLAMINE
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AZIONI PERIFERICHE DELLA DOPAMINA
Recettori D1(distretti vascolari renale, mesenterico e coronarico)
Recettori 1(cardiaci)
Vasodilatazione; RBF, GFR e secrezione di Na+
Effetto inotropo e cronotropo +
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MALATTIA DI PARKINSON
Segni cardinali
(1) Bradicinesia(2) Rigidità muscolare(3) Tremore a riposo(4) Deficit dell’equilibrio posturale
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MALATTIA DI PARKINSON
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LEVODOPALEVODOPA
Tratto GI Sangue e tessuti periferici
Cervello
90% 9%
1%DDC
MAO
COMT
DDC
MAO
COMT
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tolcapone
X
selegiline
X
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