book1
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GTRANSCRIPT
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Efek samping Placebo Bevacizumab
Neutropenia 140 136 0.3675 0.3523 Febrile neutropenia 16 18 0.0420 0.0466 anemia 53 40 0.1391 0.1036 Decreased appetipe 41 32 0.1076 0.0829 Nausea 39 27 0.1024 0.0699 Vomitting 34 24 0.0892 0.0622 Diarrhea 17 32 0.0446 0.0829 Hypokalemia 21 13 0.0551 0.0337 Hand-foot syndrome 13 25 0.0341 0.0648 Pulmonary embolism 18 12 0.0472 0.0311
Venous thromboembolic 36 25 0.0945 0.0648 arterial thromboembolic 8 5 0.0210 0.0130 hypertension 2 24 0.0052 0.0622 Hemorrhage 9 9 0.0236 0.0233 GI perforation 1 9 0.0026 0.0233 Congestive heart failure 1 2 0.0026 0.0052 proteinura 0 2 0 0.0052 wound complication 0 2 0 0.0052
0 1 0 0.0026
fistula/abscess 0 0 0 0
CER (placebo)
EER (bevacizumab)
Bevacizumab special adverse event
reversible posterior leukoencephalopathy syndrome
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ARR NNH JUMLAH PLACEBO JUMLAH BEVACIZUMAB
0.0151 66 381 3860.0046 217 381 386
0.0355 28 381 3860.0247 40 381 3860.0324 31 381 3860.0271 37 381 3860.0383 26 381 386
0.0214 47 381 3860.0306 33 381 386
0.0162 62 381 386
0.0297 34 381 3860.0080 124 381 3860.0569 18 381 386
0.0003 3268 381 3860.0207 48 381 3860.0026 385 381 3860.0052 192 381 3860.0052 192 381 386
0.0026 385 381 386
0 0 381 386
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JUMLAH BEVACIZUMAB
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