724 BOOK REVIEWS Mayo Clin Proc, October 1985, Vol 60

of the role of matching of histocompatibility antigens in various types of allografts.

Although the editors are to be commended on the generally logical format of the work and the excellent summary reports, the book is simply a comprehensive collection of the approximately 280 presentations at the conference.

The book wil l be used (as have its predecessors) as a "bible" in tissue-typing laboratories because of its exten­sive data on the reaction patterns of thousands of sera and cells used in the workshop. It is not a formal textbook to be read chapter by chapter, but it should be useful as a reference source for definition of the often idiosyncratic reaction patterns of certain antigens and their sera.

Although comprehensive detailed accounts of all the antigens shown to be linked or associated with diseases are not provided, interesting new data from recent studies in patients with certain rheumatologic, malignant, or endocrinologic disorders are included. The section on the analysis of HLA at the DNA level is particularly interesting.

Not all the data on transplantation and on the role of blood transfusions are new; however, the information was updated at the time of the conference in 1984. Hence, readers familiar with the literature in these fields may find little material with which to whet their appe­tites.

The book is superbly printed and bound, and high-quality paper has been used. Consequently, it is consid­erably less bulky than its predecessors yet contains at least as much information.

Although those directly involved in the performance and interpretation of cellular and serologic histocompat­ibility testing wil l want to have this book in their laborato­ries and wil l use it frequently, it wi l l also be of intermittent use as a reference source for those who may be involved in studies of HLA and related diseases.

S. Breanndan Moore, Μ.Β.,Β.Οι. , D.C.H. Department of Laboratory Medicine

Gastrointestinal Disorders of the Elderly, by Lawrence J. Brandt, 636 pp, with illus, $68, New York, Raven Press, 1984

With the increase in the number of elderly people in our society, interest in the process of aging and in the field of geriatric medicine has expanded. Brandt wrote this text­book to provide a comprehensive summary of the current

knowledge of the aging gut and gastrointestinal disorders in elderly people.

The book is divided into 11 chapters that sequentially cover the oral cavity, the entire alimentary tract, the liver, the biliary tract, and the pancreas. Specific chapters on ischemic disorders of the intestine and diseases of the mesentery, peritoneum, and retroperitoneum are includ­ed. Degenerative processes, late complications of com­mon diseases that frequently occur in elderly persons, and various manifestations of common digestive disor­ders in the elderly population are emphasized. The chap­ter on the oral cavity is an excellent summary of mouth disorders associated with systemic diseases. The discus­sions of diverticulosis and ischemic disorders of the intestine are superb.

Overall, the text is a useful, well-written summary of geriatric gastroenterology. The wealth of practical infor­mation is punctuated with quotations and historical backgrounds of digestive disorders. The material should appeal to the novice or the experienced gastroenterolo-gist. Ample illustrations and tables complement the text. Although the color photographs of endoscopic lesions are clear, too few (only 16) have been included for a text of this quality. In the next edition, inclusion of many more color illustrations should be considered.

This book is an excellent overview of digestive disor­ders in elderly persons. I recommend it as a valuable reference text to physicians in training and to both aca­demic and practicing internists, gastroenterologists, and geriatricians.

Thomas R. Viggiano, M.D. Division of Gastroenterology

and Internal Medicine

BOOKS RECEIVED

AIDS: Etiology, Diagnosis, Treatment, and Preven­tion, edited by Vincent T. DeVita, Jr., Samuel Hellman, and Steven A. Rosenberg, 352 pp, with illus, $38, Phil­adelphia, J. B. Lippincott Company, 1985

The Twilight Years of Lady Osier, by Frederick B. Wagner, Jr., 144 pp, with illus, $20, Canton, Massachu­setts, Science History Publications (distributed by Wat­son Publishing International, Canton, Massachusetts), 1985

Mayo Clin Proc, October 1985, Vol 60 BOOKS RECEIVED 725

Endocrine Tumours: The Pathobiology of Regulatory Peptide-Producing Tumours (Current Problems in Tu­mour Pathology, Vol 1), edited by Julia M. Polak and Stephen R. Bloom, 288 pp, with illus, $59, New York, Churchill Livingstone (distributed by Longman, White Plains, New York), 1985

Endocrinology (Management of Common Diseases in Family Practice series), by P. Marsden and A. G. Mc-Cullagh, 192 pp, with illus, $15, Littleton, Massachu­setts, PSG Publishing Company, 1985

Bronchial Carcinoma: An Integrated Approach to Diagnosis and Management, edited by Michael Bates, 295 pp, with illus, $52, New York, Springer-Verlag, 1984

Scientific Basis of Obstetrics & Gynaecology, 3rd ed, edited by Ronald R. Macdonald, 520 pp, with illus, $59, New York, Churchill Livingstone (distributed by Long­man, White Plains, New York), 1985

Neuro-ophthalmology: Clinical Signs and Symptoms, 2nd ed, by Thomas J. Walsh, 499 pp; with illus, $47.50, Philadelphia, Lea & Febiger, 1985

A Synopsis of Children's Diseases, 6th ed, by John Rendle-Short, O. Peter Gray, and John A. Dodge, 556 pp, with illus, $29.50, Bristol, England, John Wright & Sons (distributed by PSG Publishing Company, Littleton, Massachusetts), 1985

Emergency Management of Pediatric Trauma, edited by Thorn A. Mayer, 552 pp, with illus, $60, Philadelphia, W. B. Saunders Company, 1985

Gastro-esophageal Reflux in Childhood; Problems of Splenic Surgery in Childhood (Progress in Pediatric Sur­gery, Vol 18), edited by Peter Wurnig and Ingrid Klos, 193 pp, with illus, $46, New York, Springer-Verlag, 1985

Electromyography and Evoked Potentials: Theories and Applications (Advances in Applied Neurological Sciences, Vol 1), edited by Albrecht Struppler and Adolf Weindl, 268 pp, with illus, $32.50, New York, Springer-Verlag, 1985

Dyskinesia: Research and Treatment (Psychopharma-cology, Suppl 2), edited by Daniel E. Casey, Thomas N. Chase, Anne Vibeke Christensen, and Jes Gerlach, 230 pp, with illus, $39.50, New York, Springer-Verlag, 1985

Catecholamines as Hormone Regulators (Serono Sym­posia Publications From Raven Press, Vol 18), edited by Nira Ben-Jonathan, Janice M. Bahr, and Richard I. Wei-ner, 382 pp, with illus, $39.50, New York, Raven Press, 1985

Autoimmunity and Endocrine Disease (Basic and Clin­ical Endocrinology, Vol 5), edited by Robert Volp£, 473 pp, with illus, $75, New York, Marcel Dekker, 1985

The Chemistry and Biology of Isoquinoline Alkaloids (Proceedings in Life Sciences series), edited by J. David Phillipson, Margaret F. Roberts, and M. H. Zenk, 304 pp, with illus, $39, New York, Springer-Verlag, 1985

Research: How To Plan, Speak and Write About It, edited, by Clifford Hawkins and Marco Sorgi, 184 pp, with illus, $18, New York, Springer-Verlag, 1985

Flint's Emergency Treatment and Management, 7th ed, by Harvey D. Cain, 842 pp, with illus, $34.95, Philadelphia, W. B. Saunders Company, 1985

Respiratory Pharmacology and Toxicology (Saunders Monographs in Pharmacology and Therapeutics series), by Mannfred A. Hollinger, 202 pp, with illus, $19.95, Philadelphia, W. B. Saunders Company, 1985

Atlas of Endometrial Histopathology, by Gisela Dal-lenbach-Hellweg and Hemming Poulsen, 229 pp, with illus, $70, Philadelphia, W. B. Saunders Company, 1985

Rypins' Medical Licensure Examinations: Topical Summaries and Questions, 14th ed, edited by Edward D. Fröhlich, 1,094 pp, with illus, $49, Philadelphia, J. B. Lippincott Company, 1985

Virology, edited by Bernard N. Fields, David M. Knipe, Robert M. Chanock, Joseph L. Melnick, Bernard Roizman, and Robert E. Shope, 1,614 pp, with illus, $149.50, New York, Raven Press, 1985

Regional Anesthesia, 4th ed, by John Adriani, 728 pp, with illus, $75, St. Louis, Warren H. Green, 1985

Nuclear Medicine Annual 1985, edited by Leonard M. Freeman and Heidi S. Weissmann, 352 pp, with illus, $59.50, New York, Raven Press, 1985

Gastro-esophageal Reflux Disease: Pathogenesis, Diagnosis, Therapy, edited by Donald O. Castell, Wal­lace C. Wu, and David J. Ott, 324 pp, with illus, $42.50, Mount Kisco, New York, Futura Publishing Company, 1985: ^

Sleep: Neurotransmitters and Neuromodulators, ed­ited by Albert Wauquier, J. M. Gaillard, J. M. Monti, and M. Radulovacki, 344 pp, with illus, $57, New York, Raven Press, 1985

Chronic Treatments in Neuropsychiatry (Advances in Biochemical Psychopharmacology, Vol 40), edited by Dargut Kemali and Georgio Racagni, 219 pp, with illus, $45, New York, Raven Press, 1985

Ultrasound Physics and Instrumentation, by David L. Hykes, Wayne R. Hedrick, and Dale E. Starchman, 247 pp, with illus, $36, New York, Churchill Livingstone, 1985

latrogenic Disorders of the Fetus, Infant, and Child, Vol 2 (Radiology of latrogenic Disorders series), edited by E. George Kassner, 500 pp, with illus, $165, New York, Springer-Verlag, 1985

726 BOOKS RECEIVED Mayo Clin Proc, October 1985, Vol 60

Anatomy as a Basis for Clinical Medicine, by E. C. B. Hall-Craggs, 658 pp, with illus, $36, Baltimore, Urban & Schwarzenberg, 1985

Respiratory Problems (RN Nursing Assessment, Vol 5), by Ellen K. Boyda, 216 pp, with illus, $12.95, Ora-dell, New Jersey, Medical Economics Books, 1985

Head and Spine Imaging, edited by Carlos F. Gon­zalez, Charles B. Grossman, and Joseph C. Masdeu, 952 pp, with illus, $150, New York, John Wiley & Sons, 1985

Pharmacology: A Review With Questions and Expla­nations, by Manuchair Ebadi, 263 pp, with illus, $17.95, Boston, Little, Brown & Company, 1985

Occupational Therapy for Psychiatric Diseases: Mea­surement and Management of Cognitive Disabilities, by Claudia Kay Allen, 408 pp, with illus, $34.95, Boston, Little, Brown & Company, 1985

Dual Regulation of Adenylate Cyclase (Advances in Cyclic Nucleotide and Protein Phosphorylation Re­search, Vol 19), edited by Dermot M. F. Cooper and Kenneth B. Seamon, 334 pp, with illus, $59, New York, Raven Press, 1985

Complement, edited by Hans J. Müller-Eberhard and Peter A. Miescher, 474 pp, with illus, $52, New York, Springer-Verlag, 1985

Primary Health Care in the Making, edited by Ulrich Laaser, Raoul Senault, and Herbert Viefhues, 545 pp, with illus, $56.60, New York, Springer-Verlag, 1985

Manual of Otolaryngology: Diagnosis and Therapy, edited by Marshall Strome, James Kelly, and Marvin Fried, 212 pp, $16.95, Boston, Little, Brown & Com­pany, 1985

Manual of Surgical Therapeutics, 6th ed, edited by Robert E. Condon and Lloyd M. Nyhus, 482 pp, with illus, $17.95, Boston, Little, Brown & Company, 1985

Leukemia (Life Sciences Research Report, No. 30), edited by I. L. Weissman, 315 pp, with illus, $25, New York, Springer-Verlag, 1985

Core Text of Neuroanatomy, 3rd ed, by Malcolm B. Carpenter, 471 pp, with illus, $22.95, Baltimore, Wi l ­liams & Wilkins, 1985

A Concise Guide to the Management of Poisoning, 3rd ed, by John A. Vale and Tim J. Meredith, 222 pp, with illus, $15, New York, Churchill Livingstone (distributed by Longman, White Plains, New York), 1985

Current Trends in Urology, Vol 3, edited by Martin I. Resnick, 158 pp, with illus, $36, Baltimore, Williams & Wilkins, 1985

Pediatric Orthopedics of the Lower Extremity: An Instructional Handbook, by John D. McCrea, 352 pp, with illus, $42.50, Mount Kisco, New York, Futura Pub­lishing Company, 1985

Handbook of Regional Anesthesia, edited by P. Prithvi Raj, 285 pp, with illus, $40, New York, Churchill Liv­ingstone (distributed by Longman, White Plains, New York), 1985

Chemistry of the Prostaglandins and Leukotrienes (Advances in Prostaglandin, Thromboxane, and Leu-kotriene Research, Vol 14), edited by John E. Pike and Douglas R. Morton, Jr., 444 pp, with illus, $59, New York, Raven Press, 1985

Morphology and Innervation of the Fish Heart (Ad­vances in Anatomy, Embryology and Cell Biology, Vol 89), by Robert M. Santer, 102 pp, with illus, $24, New York, Springer-Verlag, 1985

Clinical Investigations, by Allen Bernard Shaw, 298 pp, with illus, $9.95, Philadelphia, Bailliere Tindall (dis­tributed by W. B. Saunders Company, Philadelphia), 1984

Current Perspectives in the Immunology of Respi­ratory Diseases (Contemporary Issues of Clinical Immu­nology and Allergy, Vol 3), 167 pp, with illus, $33, New York, Churchill Livingstone (distributed by Longman, White Plains, New York), 1985

Common Eye Diseases and Their Management, by N. R. Galloway, 278 pp, wi th il lus, $35, New York, Springer-Verlag, 1985

Social Organization of Medical Work, by Anselm Strauss, Shizuko Fagerhaugh, Barbara Suczek, and Car­olyn Wiener, 310 pp, with illus, $25, Chicago, Univer­sity of Chicago Press, 1985

Arterial Blood Gases: A Self-Study Manual, by John G. Watkins, Jr., 477 pp, with illus, $19.75, Philadelphia, J. B. Lippincott Company, 1985

Correlative Neuroanatomy & Functional Neurology, 19thed, by Joseph G. Chusid, 513 pp, with illus, $19.50, Los Altos, California, Lange Medical Publications, 1985

Rabies in the Tropics, edited by Ernst Kuwert, Charles Merieux, Hilary Kaprowski, and Konrad Bögel, 786 pp, with illus, $52, New York, Springer-Verlag, 1985

Combining Psychotherapy and Drug Therapy in Clini­cal Practice, edited by Bernard D. Beitman and Gerald L. Klerman, 242 pp, with illus, $35, Jamaica, New York, SP Medical & Scientific Books, 1984

Radionuclide Imaging of the Brain (Contemporary Issues in Nuclear Imaging, Vol 1), edited by B. Leonard Holman, 232 pp, with illus, $55, New York, Churchill Livingstone (distributed by Longman, White Plains, New York), 1985

Brain Imaging and Brain Function (Research Pub­lications: Association for Research in Nervous and Men­tal Disease, Vol 63), edited by Louis Sokoloff, 290 pp, with illus, $59.50, New York, Raven Press, 1985