Business Meeting IG Infection & Allergy

Monday 18th June 2012

Agenda1. Lecture: "Clinical relevance of superantigens in allergic

disease. Task force conclusions".Professor Philippe Gevaert, Chair of the Task Force on Superantigens.

2. IG board and membership3. I&A sessions at EAACI 20124. I&A Allergy School Edinburgh5. Influenza vaccination in allergy – questionnaire6. Influenza summit Brussels7. New I&A task force – suggestions please

Board 2011-2013

Chairperson Jürgen SchwarzeUnited Kingdomjurgen.schwarze@ed.ac.uk

• Secretary Chrysanthi SkevakiGreececskevaki@allergy.gr

• Members Carsten Flohrcarsten.flohr@kcl.ac.ukPhilippe Gevaertphilippe.gevaert@UGent.be

• JMA Affiliate Heidi Makriniotiheidimakrinioti@gmail.com

• Webmaster Chrysanthi Skevakicskevaki@allergy.gr

Membership (2010-2012)

I&A Sessions

at EAACI 2012

Oral abstract sessions

Sunday, 17 June 201210:30 - 12:00

"Role of infections in chronic inflammation"

Tuesday, 19 June 201215:30 - 17:00

"Interplay between infections and allergy"

• Saturday, 16 June 201214:00 - 15:30From Innate immunity to allergyIntestinal microbiota and allergic immune response, Charles Mackay, Australia

Sunday, 17 June 201213:30 - 15:00SymposiumNovel epidemiological insights on asthma and infectionRespiratory virus in the inception of childhood asthma, Robert Lemanske, United States

Role of rhinovirus C in childhood asthma, Peter Le Souef, Australia

Bacterial colonisation as a risk factor for initiation and expression, Hans Bisgaard, Denmark

15:30 - 17:00SymposiumHow can anti-infective drugs influence allergic disease?Antivirals, Peter Openshaw, United Kingdom

Antibiotics, Thibaut van Zele, Belgium

Antiparasitics, Maria Yazdanbakhsh, The Netherlands

15:30 - 17:00SymposiumMicrobiota, nutrition and allergic diseasesProbiotics and prebiotics for the prevention and treatment, Matthias Kopp, Germany

15:30 - 17:00JMA Scientific SymposiumBronchiolitis and the infant immune system, Maggina Paraskevi, Greece

• Monday, 18 June 201207:00 - 07:45Meet the ExpertsMeet the Expert 15 - Vaccinations in allergic children, Christoph Gruber, Germany

09:00 - 10:30Plenary Symposium 4Revisiting the origins of allergyHow does the microenvironment shape the allergic response?, Stephen Holgate, United Kingdom

10:45 - 12:15symposiumUnderstanding urticariaGerms and worms in urticaria, Peter Schmid-Grendelmeier, Switzerland

13:30 - 15:00Business Meeting Interest Group Infections & AllergyClinical relevance of superantigens in allergic disease.  Task force conclusions, Philippe Gevaert, Belgium

15:30 - 17:00SymposiumViral mechanisms in airway inflammation Innate immune mechanisms in viral bronchiolitis - from mouse to infant, Riny Janssen, The Netherlands

Interferon response in virus-induced asthma, Sebastian Johnston, united Kingdom

Viral and bacterial interactions: their role in driving airway inflammation, Chrysanthi Skevaki, Greece

15:30 - 17:00SymposiumEAACI meets RussiaThe interaction of RSV and epithelial cells in the lung, Musa Khaitov, Russia

• Tuesday, 19 June 201208:30 - 10:00Meet the Expert 21Environmental pressure on epigenetic changes, William Cookson, United Kingdom

13:00 - 13:30Pro & Con 6Probiotics and prebiotics can reduces the incidence of infantile eczema, Pro: Philippe Eigenmann, SwitzerlandCon: Matthias Kopp, Germany

15:30 - 17:00Business MeetingAsthma SectionAsthma exacerbation, Sebastian Johnston

15:30 - 17:00Business MeetingPediatrics SectionPrebiotics and probiotics in allergy prevention and treatment: true or false?, Hania Szajewska, Poland

Wednesday, 20 June 201208:30 - 10:00Plenary Symposium 7Risk factors for allergyInfections at the inception of allergy, Nikos Papadopoulos, Greece

10:30 - 12:00SymposiumMolecular profiling of allergy and inflammationImmunoproteomics: inflammatory response to staphylococcal superantigens, Barbara Broker,

Clinical Impact and Mechanismsof Infections in Allergy

15 – 18 September 2011Edinburgh, UK

 

 

 

 

 

8

9

Clinical impact and mechanisms of infections in allergy

15 – 18 September 2011Edinburgh, UK

63 participants & 19 speakers

EAACI Members

13

EAACIJuniors

34

Non EAACI 14

63

28 Countries

UK 18

Russia 13

Germany 8

Greece 5

Austria, Belgium, Poland, The Netherlands

3

Switzerland, Thailand, Brazil, Republic of Korea, Slovenia, Romania

2

Ghana, Denmark, Kazakhstan, Canada, Portugal, USA, Uzbekistan, Sweden, Albania, India, Czech Republic, Bosnia, Japan, Turkey

1

ALLERGY SCHOOLS 2011

Local organizer: Jürgen Schwarze

13 CME credits

Influenza vaccination in allergyquestionnaire

• 241 respondents• 60% allergists, 30% paediatricians

• The majority of participants (82%) advocate their patients to become vaccinated

• Half of participants have been involved in influenza immunization programmes

• IFV immunization of asthmatic/allergic patients is largely performed by GPs and pediatricians

Does your department provide adequate staff and resources for influenza vaccination campaigns?

36.9

18.4 17.510.7 16.5

0

50

100

%

Resources for influenza vaccination campaignsare little or not adequate at all

Half of participants have been involved in influenza immunization programmes

EAACI I&A IG Survey 2012

Do you feel the level of influenza awareness among patients with asthma / respiratory allergy is satisfactory?

21.829.1 32.5

11.74.9

0

50

100

1-Not a

t all 2- 3- 4-

5-Completely

%

Half of physicians feel that the level of awareness among asthmatics

is little or not satisfactory at all

EAACI I&A IG Survey 2012

What is the vaccination rate of your asthmatic patients?

EAACI I&A IG Survey 2012

The majority estimates <40% vaccination coverage of their patients

Similarly, low estimates for asthma patients with egg allergy

I don't know/NA

28,4%

Other 71,6%

80-100%60-80%

40-60%

20-40%

1-20%

What are the reasons, beliefs, attitudes affecting declination rates among allergic individuals?

EAACI I&A IG Survey 2012

Declination of vaccination is strongly affected by a number of misconceptions

Education on vaccine

efficacy/safety should be one of

the priority public health

measures taken

Other 19,8%

Vaccination exacerbates

asthma 19,8%

Allergy to vaccine is common

20,3%

Vaccine is expensive 24%

Egg allergy precludes

vaccination 28,6%

Vaccination is responsible for flu symptoms

46,4%

Vaccination is painful 22,9%

What is the vaccination rate among physicians working in your Department?

16.5 19.1 15.4 14.9 13.8 20.2

0

50

100

1-20 %20-40 %

40-60 %60-80 %

80-100 %

I don't know/Does not apply

%

EAACI I&A IG Survey 2012

Half of respondents report vaccination rates <60% among physicians

• Additional resources are needed for vaccination campaigns.

• The level of influenza awareness among patients with asthma should be enhanced.

• Vaccination rate of asthmatic patients remains low despite recommendations by their physicians.

• Declination of vaccination among allergic individuals is affected by misconceptions, which may be cleared up with suitable education.

Conclusions

2nd ESWI Flu Summit

•Network of Partner Organizations: European Public Health Alliance, International Diabetes Federation-EU, WHO-EU, ESPID, EAP, EAACI, WONCA-EU, ELF, ERS, EMA, EUGMS, EUREGHA, National Influenza Vaccine Summit, PGEU

•Showcase successful projects that raised patients’ awareness

•~100 representatives of health care providers, senior citizens, at-risk patients and public health authorities: platform to expand efforts, exchange practices and initiate concrete actions, influenza challenges ahead

•WHO Europe (respir path progr), EC Directorate-General for Health and Consumers, ESWI Chair & Vice-Chair, EMA, American Medical Association, ESPID, Pharmacy Union, EUGMS, Turkish Ministry of Health

• Reported prevalence of influenza in AAE among children & adults

• Influenza attributable health care utilization

• Vaccine Effectiveness (CS intake)

• Vaccine Efficacy

• Vaccine Safety

• Selection of vaccine: TIV vs LAIV

• Compliance of asthmatics to current vaccine recommendations

Task Force: “Influenza in asthma”

18