Down SyndromeAKA: Trisomy 21

By: Olivia Piazza, Jessica Selensky, and Alex Ford

Mrs. G-M Period #8

http://www.model7466.net/model-mania-4u.html

http://www.cdadc.com/ds/down-syndrome-children-down-syndrome-pictures.html

https://rhodribrady.wordpress.com/tag/chromosome/

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Due: Tuesday February 8th

How Is Down Syndrome Inherited?This disorder is caused by a chromosomal

abnormalityOccurs when there is one extra chromosomeChromosome 21 http://learn.genetics.utah.edu/content/disorders/whataregd/down/

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Is It Possible for Someone to be a Carrier? YesIt is possible for someone to be a carrier

They may have a chromosome with the disease, and they just may not show it

http://www.ayushveda.com/tipson/downs-syndrome/See the notes below

What is the Frequency of Down Syndrome?It is one of the most common defectsAffects many babies in the USIt is said that there are more than 400,000

people with Down Syndrome in the US

http://www.uic.edu/classes/bios/bios100/lectures/mitosis.htmSee the notes below

What are the symptoms/effects and prognosis of someone with Down Syndrome?Small headFlat faceShort statureCreasing of skin on the back of handsEyes slant upward at the cornersSmall ears that may fold over at the topA small mouth, making the tongue appear largeA small nose with a flattened nasal bridgeA short neckSmall hands and feetLow muscle Tone66-89% of Down patients have some level of hearing loss in

at least one ear

http://www.healthbama.com/about-the-down-syndrome/

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Continuation of; What are the symptoms/effects and prognosis of someone with Down Syndrome?These affects may only occur in some people.Children with Down Syndrome have more

viruses and infections.People with Down Syndrome are more likely

to develop other diseases½ the babies with Down Syndrome have heart

defectThe risk of leukemia is 10-15 times higher

than in non-Down people R

http://www.newbornbabyzone.com/health-safety/downs-syndrome-identifying-it-and-living-with-it/See the notes below

How is Down Syndrome Diagnosed?There are many ways that Down Syndrome is

diagnosed. Some of the ways include:

Flabby muscle tonePoor coordinationNarrow ear canalsLow resistance to ear infectionsWeak visionMisshapen teethMalformations Hypothyroidism

http://aboutmyrecovery.com/2011/01/04/special-and-gifted-children/See the notes below

Continuation of; How is Down Syndrome Diagnosed?TestingBEFORE BIRTH:

Screening Nuchal Translucency Testing Triple/Quadruple Screening Integrated Screen Ultrasound

Diagnostic Chorionic Villus Sampling (CVS) Amniocentesis Percutaneous Umbilical Blood Sampling (PUBS)

http://www.fetal.com/Genetic%20Sono/01_what%20is%20gen%20us.htmlSee the notes below

What is the Treatment for Down Syndrome, If Any?There is not a treatment for the disease itself,

but there are treatment for the diseases/problems that may be a result of Down Syndrome.Heart/Gastrointestinal

Surgery Bacterial infections

Antibiotics Viral/Fungal infections

Certain drugs

New treatments every dayhttp://www.dukechildrens.org/services/medical_genetics/down_syndrome_clinicSee the notes below

Continuation of; What is the Treatment for Down Syndrome?Learning/Social

Early Intervention Specialized ProgramsKids still go to school

They learn the same things, just differently, and at a different, slower pace

http://www.ehow.com/how_2100050_pick-school-down-syndrome-child.htmlSee the notes below

Is There a Cure to Down Syndrome? There is not a cure for Down Syndrome… yet.But there are many people who are working

with those who do have Down Syndrome.TherapistsTeachersParents

They all nurture the people who do have Down Syndrome.

http://www.cdadc.com/ds/

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Works ConsultedDown Syndrome. Birth Defects. National Down Syndrome Society. 2009. <www. Marchofdimes.com/> 29 January 2011.Down syndrome. Third Revised Edition DISEASES. Bryan Bunch, Jenny Tesar.                 Danbury, CT. Scholastic Library Publishing, 2006. 28 January 2011. Evans- Martin, Fay. Down Syndrome. Genes and Disease. New York, New York.                 Infobase Publishing, 2009. 28 January 2011.Knight, Jeffrey A. Down Syndrome. Salem Health Genetics And Inherited Conditions. Pasadena. Salem Press, 2010. 28 January 2011.Windelspecht, Michael. Down Syndrome. Diseases and Disorders. Wendy Horobin.             Marry Town, NY. Marchall Cavendish Corporation, 2008. 28 January 2011.Down Syndrome. Kids Health. 2010. <www.kidshealth.org/> 29 January 2011.Down Syndrome. Your Genes, Your Health. <ygyh.org/> 29 January 2011.Heyn, Sietske N. Down Syndrome. MedicineNet. <medicine.net.com/> 29 January 2011.