1999 carbohydrates

carbohydratesU 0500

50 - 211Extended Alkenyl Glycosides by Ruthenium-Catalyzed Cross-Metathesis Reaction and Application Toward Novel C-LinkedPseudodisaccharides. — Cross-metathesis of O- and C-allyl galactopyra-nosides (I) and (X) with various olefins in the presence of Grubb’s rutheniumcatalyst yields the corresponding carbohydrate derivatives in high yields andwith good to high stereoselectivity. This simple method is of general interest andproceeds under very mild and neutral conditions with the catalyst remaininghighly active in the presence of a wide variety of functional groups. — (ROY,RENE; DOMINIQUE, ROMYR; DAS, SANJOY K.; J. Org. Chem. 64 (1999)15, 5408-5412; Dep. Chem., Univ. Ottawa, Ottawa, Ont. K1N 6N5, Can.; EN)

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