cheminform abstract: synthesis of optically pure n-boc-protected (2r,3r)- and...

2001 amino acids, peptides amino acids, peptides U 0400 18 - 167 Synthesis of Optically Pure N-Boc-protected (2R,3R)- and (2R,3S)- 3-Fluoroprolines. — Starting from (2S,3S)-3-hydroxyproline derivatives such as (I) and (III), the N-Boc-protected optically pure target compounds are prepared as novel probes for studying the cis/trans isomerization of the amino acyl-proline peptide bond. — (DEMANGE, LUC; CLUZEAU, JEROME; MENEZ, ANDRE; DUGAVE, CHRISTOPHE; Tetrahedron Lett. 42 (2001) 4, 651-653; Dep. Ing. Etud. Proteines, Cent. Etud. Saclay, F-91191 Gif-sur- Yvette, Fr.; EN) 1

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Page 1: ChemInform Abstract: Synthesis of Optically Pure N-Boc-protected (2R,3R)- and (2R,3S)-3-Fluoroprolines

2001 amino acids, peptides

amino acids, peptidesU 0400

18 - 167Synthesis of Optically Pure N-Boc-protected (2R,3R)- and (2R,3S)-3-Fluoroprolines. — Starting from (2S,3S)-3-hydroxyproline derivativessuch as (I) and (III), the N-Boc-protected optically pure target compounds areprepared as novel probes for studying the cis/trans isomerization of the aminoacyl-proline peptide bond. — (DEMANGE, LUC; CLUZEAU, JEROME;MENEZ, ANDRE; DUGAVE, CHRISTOPHE; Tetrahedron Lett. 42 (2001)4, 651-653; Dep. Ing. Etud. Proteines, Cent. Etud. Saclay, F-91191 Gif-sur-Yvette, Fr.; EN)

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