2001 alkaloids

alkaloidsU 0600

46 - 233Synthesis of the Heterocyclic Core of the Alkaloids Martinellineand Martinellic Acid. — The imino Diels–Alder reaction of (I) derivedfrom cinnamaldehyde with the cyclic enamide (II) proceeds with completeregio- and poor diastereoselectivity. The exo-product (IV) is readily elabo-rated to compound (V) representing the core of martinelline and martinellicacid. — (HADDEN, MARK; NIEUWENHUYZEN, MARK; OSBORNE,DAIRE; STEVENSON, PAUL J.; THOMPSON, NORRIS; Tetrahedron Lett.42 (2001) 36, 6417-6419; Sch. Chem., Queen’s Univ., Belfast BT9 5AG, UK; EN)

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