circulation l. case number: 185 clinical: male aged 70 years.bcc immuno: pancytokeratin shows strong...

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Circulation L

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Page 1: Circulation L. Case number: 185 Clinical: Male aged 70 years.BCC Immuno: Pancytokeratin shows strong positivity in centre of lymphoid islands. EBV negative

Circulation L

Page 2: Circulation L. Case number: 185 Clinical: Male aged 70 years.BCC Immuno: Pancytokeratin shows strong positivity in centre of lymphoid islands. EBV negative

Case number: 185

Clinical: Male aged 70 years. ?BCC

Immuno: Pancytokeratin shows strong positivity in centre of lymphoid islands. EBV negative.

Page 3: Circulation L. Case number: 185 Clinical: Male aged 70 years.BCC Immuno: Pancytokeratin shows strong positivity in centre of lymphoid islands. EBV negative
Page 4: Circulation L. Case number: 185 Clinical: Male aged 70 years.BCC Immuno: Pancytokeratin shows strong positivity in centre of lymphoid islands. EBV negative
Page 5: Circulation L. Case number: 185 Clinical: Male aged 70 years.BCC Immuno: Pancytokeratin shows strong positivity in centre of lymphoid islands. EBV negative
Page 6: Circulation L. Case number: 185 Clinical: Male aged 70 years.BCC Immuno: Pancytokeratin shows strong positivity in centre of lymphoid islands. EBV negative
Page 7: Circulation L. Case number: 185 Clinical: Male aged 70 years.BCC Immuno: Pancytokeratin shows strong positivity in centre of lymphoid islands. EBV negative
Page 8: Circulation L. Case number: 185 Clinical: Male aged 70 years.BCC Immuno: Pancytokeratin shows strong positivity in centre of lymphoid islands. EBV negative
Page 9: Circulation L. Case number: 185 Clinical: Male aged 70 years.BCC Immuno: Pancytokeratin shows strong positivity in centre of lymphoid islands. EBV negative
Page 10: Circulation L. Case number: 185 Clinical: Male aged 70 years.BCC Immuno: Pancytokeratin shows strong positivity in centre of lymphoid islands. EBV negative

Most popular diagnosis

Lymphoepithelioma-like carcinoma

Page 11: Circulation L. Case number: 185 Clinical: Male aged 70 years.BCC Immuno: Pancytokeratin shows strong positivity in centre of lymphoid islands. EBV negative

Case number: 186

Clinical: Male 44. Excision of irritated skin lesion behind right ear.

Specimen: Skin tag.

Macro: A grey polypoid fragment of skin 9x5x5mm.

Page 12: Circulation L. Case number: 185 Clinical: Male aged 70 years.BCC Immuno: Pancytokeratin shows strong positivity in centre of lymphoid islands. EBV negative
Page 13: Circulation L. Case number: 185 Clinical: Male aged 70 years.BCC Immuno: Pancytokeratin shows strong positivity in centre of lymphoid islands. EBV negative
Page 14: Circulation L. Case number: 185 Clinical: Male aged 70 years.BCC Immuno: Pancytokeratin shows strong positivity in centre of lymphoid islands. EBV negative
Page 15: Circulation L. Case number: 185 Clinical: Male aged 70 years.BCC Immuno: Pancytokeratin shows strong positivity in centre of lymphoid islands. EBV negative
Page 16: Circulation L. Case number: 185 Clinical: Male aged 70 years.BCC Immuno: Pancytokeratin shows strong positivity in centre of lymphoid islands. EBV negative
Page 17: Circulation L. Case number: 185 Clinical: Male aged 70 years.BCC Immuno: Pancytokeratin shows strong positivity in centre of lymphoid islands. EBV negative
Page 18: Circulation L. Case number: 185 Clinical: Male aged 70 years.BCC Immuno: Pancytokeratin shows strong positivity in centre of lymphoid islands. EBV negative

Most popular diagnosis

Epithelioid haemangioma

Page 19: Circulation L. Case number: 185 Clinical: Male aged 70 years.BCC Immuno: Pancytokeratin shows strong positivity in centre of lymphoid islands. EBV negative

Case number: 187

Female 65 yrs.

Extending atrophic white plaque left anterior iliac region.

Macro: Elliptical piece of skin 20x6x6mm.

Page 20: Circulation L. Case number: 185 Clinical: Male aged 70 years.BCC Immuno: Pancytokeratin shows strong positivity in centre of lymphoid islands. EBV negative
Page 21: Circulation L. Case number: 185 Clinical: Male aged 70 years.BCC Immuno: Pancytokeratin shows strong positivity in centre of lymphoid islands. EBV negative
Page 22: Circulation L. Case number: 185 Clinical: Male aged 70 years.BCC Immuno: Pancytokeratin shows strong positivity in centre of lymphoid islands. EBV negative
Page 23: Circulation L. Case number: 185 Clinical: Male aged 70 years.BCC Immuno: Pancytokeratin shows strong positivity in centre of lymphoid islands. EBV negative
Page 24: Circulation L. Case number: 185 Clinical: Male aged 70 years.BCC Immuno: Pancytokeratin shows strong positivity in centre of lymphoid islands. EBV negative
Page 25: Circulation L. Case number: 185 Clinical: Male aged 70 years.BCC Immuno: Pancytokeratin shows strong positivity in centre of lymphoid islands. EBV negative
Page 26: Circulation L. Case number: 185 Clinical: Male aged 70 years.BCC Immuno: Pancytokeratin shows strong positivity in centre of lymphoid islands. EBV negative

Most popular diagnosis

Morphoea

Page 27: Circulation L. Case number: 185 Clinical: Male aged 70 years.BCC Immuno: Pancytokeratin shows strong positivity in centre of lymphoid islands. EBV negative

Case number: 188

Female aged 62. ?Multiple cysts posterior neck.

Specimen: Punch biopsyMacro: 3x3x4mm punch biopsy.

Page 28: Circulation L. Case number: 185 Clinical: Male aged 70 years.BCC Immuno: Pancytokeratin shows strong positivity in centre of lymphoid islands. EBV negative
Page 29: Circulation L. Case number: 185 Clinical: Male aged 70 years.BCC Immuno: Pancytokeratin shows strong positivity in centre of lymphoid islands. EBV negative
Page 30: Circulation L. Case number: 185 Clinical: Male aged 70 years.BCC Immuno: Pancytokeratin shows strong positivity in centre of lymphoid islands. EBV negative
Page 31: Circulation L. Case number: 185 Clinical: Male aged 70 years.BCC Immuno: Pancytokeratin shows strong positivity in centre of lymphoid islands. EBV negative
Page 32: Circulation L. Case number: 185 Clinical: Male aged 70 years.BCC Immuno: Pancytokeratin shows strong positivity in centre of lymphoid islands. EBV negative

Most popular diagnosis

Malignant, probably metastatic lobular breast 9.70

Page 33: Circulation L. Case number: 185 Clinical: Male aged 70 years.BCC Immuno: Pancytokeratin shows strong positivity in centre of lymphoid islands. EBV negative

Case number: 189

Female aged 48 years. A.L.L. Had bone marrow transplant . Had susequent GvHD. Now thickened red, swollen skin ?Leukaemic infiltrate.

Positive for CD79a, CD20, CD10, CD34, TdT. Negative for CD2, CD3 and CD117.

Page 34: Circulation L. Case number: 185 Clinical: Male aged 70 years.BCC Immuno: Pancytokeratin shows strong positivity in centre of lymphoid islands. EBV negative
Page 35: Circulation L. Case number: 185 Clinical: Male aged 70 years.BCC Immuno: Pancytokeratin shows strong positivity in centre of lymphoid islands. EBV negative
Page 36: Circulation L. Case number: 185 Clinical: Male aged 70 years.BCC Immuno: Pancytokeratin shows strong positivity in centre of lymphoid islands. EBV negative
Page 37: Circulation L. Case number: 185 Clinical: Male aged 70 years.BCC Immuno: Pancytokeratin shows strong positivity in centre of lymphoid islands. EBV negative
Page 38: Circulation L. Case number: 185 Clinical: Male aged 70 years.BCC Immuno: Pancytokeratin shows strong positivity in centre of lymphoid islands. EBV negative

Most popular diagnosis

B lymphoblastic lymphoma

Page 39: Circulation L. Case number: 185 Clinical: Male aged 70 years.BCC Immuno: Pancytokeratin shows strong positivity in centre of lymphoid islands. EBV negative

Case number: 190

Male aged 21 years. Skin lesions from back ??melanoma . Macro: A large ellipse of skin 75x33x25mm

with a central area of depigmentation 37x25mm surrounded by slightly reddish periphery.

Page 40: Circulation L. Case number: 185 Clinical: Male aged 70 years.BCC Immuno: Pancytokeratin shows strong positivity in centre of lymphoid islands. EBV negative
Page 41: Circulation L. Case number: 185 Clinical: Male aged 70 years.BCC Immuno: Pancytokeratin shows strong positivity in centre of lymphoid islands. EBV negative
Page 42: Circulation L. Case number: 185 Clinical: Male aged 70 years.BCC Immuno: Pancytokeratin shows strong positivity in centre of lymphoid islands. EBV negative
Page 43: Circulation L. Case number: 185 Clinical: Male aged 70 years.BCC Immuno: Pancytokeratin shows strong positivity in centre of lymphoid islands. EBV negative
Page 44: Circulation L. Case number: 185 Clinical: Male aged 70 years.BCC Immuno: Pancytokeratin shows strong positivity in centre of lymphoid islands. EBV negative

Most popular diagnosis

Morphoea

Page 45: Circulation L. Case number: 185 Clinical: Male aged 70 years.BCC Immuno: Pancytokeratin shows strong positivity in centre of lymphoid islands. EBV negative

Case number: 191

Male aged 60 years.

Skin left popliteal fossa excision. Five week history of nodule on skin. No pus. Has some insect bites. ?insect bite reaction, ?keratoacanthoma versus SCC.

Macro: Skin biopsy 18x13x2mm in depth with a centrally raised slightly keatotic lesion 5mm in diameter.

Page 46: Circulation L. Case number: 185 Clinical: Male aged 70 years.BCC Immuno: Pancytokeratin shows strong positivity in centre of lymphoid islands. EBV negative
Page 47: Circulation L. Case number: 185 Clinical: Male aged 70 years.BCC Immuno: Pancytokeratin shows strong positivity in centre of lymphoid islands. EBV negative
Page 48: Circulation L. Case number: 185 Clinical: Male aged 70 years.BCC Immuno: Pancytokeratin shows strong positivity in centre of lymphoid islands. EBV negative
Page 49: Circulation L. Case number: 185 Clinical: Male aged 70 years.BCC Immuno: Pancytokeratin shows strong positivity in centre of lymphoid islands. EBV negative
Page 50: Circulation L. Case number: 185 Clinical: Male aged 70 years.BCC Immuno: Pancytokeratin shows strong positivity in centre of lymphoid islands. EBV negative
Page 51: Circulation L. Case number: 185 Clinical: Male aged 70 years.BCC Immuno: Pancytokeratin shows strong positivity in centre of lymphoid islands. EBV negative
Page 52: Circulation L. Case number: 185 Clinical: Male aged 70 years.BCC Immuno: Pancytokeratin shows strong positivity in centre of lymphoid islands. EBV negative
Page 53: Circulation L. Case number: 185 Clinical: Male aged 70 years.BCC Immuno: Pancytokeratin shows strong positivity in centre of lymphoid islands. EBV negative
Page 54: Circulation L. Case number: 185 Clinical: Male aged 70 years.BCC Immuno: Pancytokeratin shows strong positivity in centre of lymphoid islands. EBV negative

 

Page 55: Circulation L. Case number: 185 Clinical: Male aged 70 years.BCC Immuno: Pancytokeratin shows strong positivity in centre of lymphoid islands. EBV negative

Case number: 192

Female aged 64 years. Ultra sound 'vascular lump'.Specimen: Lesion right neck. ExcisionMacro: Skin ellipse 35x26mm with raised

smooth lesion 25x18x10mm.

Page 56: Circulation L. Case number: 185 Clinical: Male aged 70 years.BCC Immuno: Pancytokeratin shows strong positivity in centre of lymphoid islands. EBV negative
Page 57: Circulation L. Case number: 185 Clinical: Male aged 70 years.BCC Immuno: Pancytokeratin shows strong positivity in centre of lymphoid islands. EBV negative
Page 58: Circulation L. Case number: 185 Clinical: Male aged 70 years.BCC Immuno: Pancytokeratin shows strong positivity in centre of lymphoid islands. EBV negative
Page 59: Circulation L. Case number: 185 Clinical: Male aged 70 years.BCC Immuno: Pancytokeratin shows strong positivity in centre of lymphoid islands. EBV negative

Most popular diagnosis

Granular cell tumour

Page 60: Circulation L. Case number: 185 Clinical: Male aged 70 years.BCC Immuno: Pancytokeratin shows strong positivity in centre of lymphoid islands. EBV negative

Case number: 193 Female aged 22 years. Pruritic papules and vesicles.IMF shows granular IgA in the dermal

papillae.Macro: Punch biopsy 4x4mm deep.

Page 61: Circulation L. Case number: 185 Clinical: Male aged 70 years.BCC Immuno: Pancytokeratin shows strong positivity in centre of lymphoid islands. EBV negative
Page 62: Circulation L. Case number: 185 Clinical: Male aged 70 years.BCC Immuno: Pancytokeratin shows strong positivity in centre of lymphoid islands. EBV negative
Page 63: Circulation L. Case number: 185 Clinical: Male aged 70 years.BCC Immuno: Pancytokeratin shows strong positivity in centre of lymphoid islands. EBV negative

Most popular diagnosis

Dermatitis herpetiformis

Page 64: Circulation L. Case number: 185 Clinical: Male aged 70 years.BCC Immuno: Pancytokeratin shows strong positivity in centre of lymphoid islands. EBV negative

Case number: 194 Male aged 88 years. 2-3 month history of mass on left thigh.

TTF-1 negative, CK7 negative, S100 negative. CK20 positive, Chromogranin positive, CD56

positive, Synaptophysin positive.

Ellipse of skin 80x10mm with 20mm depth bearing a pink nodule15mm dimension.

Page 65: Circulation L. Case number: 185 Clinical: Male aged 70 years.BCC Immuno: Pancytokeratin shows strong positivity in centre of lymphoid islands. EBV negative
Page 66: Circulation L. Case number: 185 Clinical: Male aged 70 years.BCC Immuno: Pancytokeratin shows strong positivity in centre of lymphoid islands. EBV negative
Page 67: Circulation L. Case number: 185 Clinical: Male aged 70 years.BCC Immuno: Pancytokeratin shows strong positivity in centre of lymphoid islands. EBV negative

Most popular diagnosis

Merkel cell carcinoma