“codon distribution in dna”

16
[pjysigs/?4?5?54\ Gbmbn Mistrieutibns in MND drZiv.brc > pjysigs > drZiv1pjysigs/?4?5?54 Mbwn`bdm1  _ M F  _bstWgript  Btjhr fbrldts Gurrhnt erbwsh gbnthxt1 pjysigs 0 prhv | nhxt > nh w  | rhghnt  | ?4?5 Uhfhrhnghs & Gitdtibns  NDWD DMW Ebbkldrk  ( wjdt is tjis2) _jysigs > Eib`bcigd` _jysigs Gbmbn Mistrieutibns in MND  D . W b l , W. Gjdttbpdmjydy , A. Gjdkrdedrti , M. Ednmybpdmjydy (Wuelitthm bn 9 Fhe 5??4) ]jh gbmbns, sixtyfbur in nulehr, drh mistrieuthm bvhr tjh gbminc pdrts bf MND shquhnghs. ]jh mistrieutibn fungtibn is tjh p`bt bf frhquhngy-vhrsus-rdnk bf tjh gbmbns. ]jhsh mistrieutibns drh gjdrdgthrishm ey pdrdlhthrs tjdt drh d`lbst univhrsd`, i.h., chnh inmhphnmhnt. ]jhrh is eut d sld`` pdrt tjdt mhphnms bn tjh chnh. Sh prhshnt tjh tjhbry tb gd`gu`dth tjh univhrsd` (chnh-inmhphnmhnt) pdrt. ]jh pdrt tjdt is chnh- sphgifig, jbwhvhr, jds unmhthrlinhm bvhr`dps dnm f`ugtudtibns. Gbl lh nts1 74 pdchs, 8 ficurhs Wueahgts1 Eib`bcigd` _jysigs (pjysigs.eib-pj) ; Mdtd Dnd`ysis, Wtdtistigs dnm _rbedei`ity (pjysigs.mdtd-dn); Tudntitdtivh Eib`bcy (q-eib) MBI1 4?.44?7/_jysUhvH.67.?849?: Gith ds1 drZiv1pjysigs/?4?5?54v4  [pjysigs.eib-pj\ Wuelissibn jistbry Frbl1 Wuady Gjdttbpdmjydy [ vihw hldi` \ [v4\ Fri, 9 Fhe 5??4 ?31?5186 CL] (5=ke) Sjigj dutjbrs bf tjis pdphr drh hnmbrshrs2 Sh crdthfu``y dgknbw`hmch suppbrtinc institutibns W hd r gj br D r ti g` h - i m ( Jh`p |  D mv dn gh m sh dr gj )  Gbrnh`` Xnivhrsity @ierdry fi`h1///G|/Mbgulhnts%5?dnm%5?Whttincs/MHEX/M hsktbp/?4?5?54.jtl (4 bf 5) [45/=/5?44 451791=3 DL\  D`` pdphrs Cb!

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Page 1: “Codon Distribution In DNA”

8/3/2019 “Codon Distribution In DNA”

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[pjysigs/?4?5?54\ Gbmbn Mistrieutibns in MND 

drZiv.brc > pjysigs > drZiv1pjysigs/?4?5?54

Mbwn`bdm1◂  _MF

◂  _bstWgript

◂  Btjhr fbrldts

Gurrhnt erbwsh gbnthxt1

pjysigs

0 prhv | nhxt > 

nhw | rhghnt |?4?5

Uhfhrhnghs & Gitdtibns

◂  NDWD DMW

Ebbkldrk  (wjdt is tjis2)

_jysigs > Eib`bcigd` _jysigs

Gbmbn Mistrieutibns in MND

 D. Wbl, W. Gjdttbpdmjydy, A. Gjdkrdedrti, M. Ednmybpdmjydy

(Wuelitthm bn 9 Fhe 5??4)

]jh gbmbns, sixtyfbur in nulehr, drh mistrieuthm bvhr tjh gbminc pdrts bf MND shquhnghs. ]jh mistrieutibn

fungtibn is tjh pbt bf frhquhngy-vhrsus-rdnk bf tjh gbmbns. ]jhsh mistrieutibns drh gjdrdgthrishm eypdrdlhthrs tjdt drh dlbst univhrsd, i.h., chnh inmhphnmhnt. ]jhrh is eut d sld pdrt tjdt mhphnms bn tjh

chnh. Sh prhshnt tjh tjhbry tb gdgudth tjh univhrsd (chnh-inmhphnmhnt) pdrt. ]jh pdrt tjdt is chnh-

sphgifig, jbwhvhr, jds unmhthrlinhm bvhrdps dnm fugtudtibns.

Gbllhnts1 74 pdchs, 8 ficurhs

Wueahgts1 Eib`bcigd` _jysigs (pjysigs.eib-pj); Mdtd Dndysis, Wtdtistigs dnm

_rbedeiity (pjysigs.mdtd-dn); Tudntitdtivh Eibbcy (q-eib)

MBI1 4?.44?7/_jysUhvH.67.?849?:

Gith ds1 drZiv1pjysigs/?4?5?54v4 [pjysigs.eib-pj\

Wuelissibn jistbry

Frbl1 Wuady Gjdttbpdmjydy [vihw hldi\

[v4\ Fri, 9 Fhe 5??4 ?31?5186 CL] (5=ke)

Sjigj dutjbrs bf tjis pdphr drh hnmbrshrs2

Sh crdthfu``y

dgknbw`hmch

suppbrtinc

institutibns

Whdrgj br Drtigh-im (Jhp | Dmvdnghm shdrgj)

 

Gbrnh`` Xnivhrsity

@ierdry

fi`h1///G|/Mbgulhnts%5?dnm%5?Whttincs/MHEX/Mhsktbp/?4?5?54.jtl (4 bf 5) [45/=/5?44 451791=3 DL\

 D`` pdphrs Cb!

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[pjysigs/?4?5?54\ Gbmbn Mistrieutibns in MND 

@ink edgk tb1 drZiv, fbrl inthrfdgh, gbntdgt.

fi`h1///G|/Mbgulhnts%5?dnm%5?Whttincs/MHEX/Mhsktbp/?4?5?54.jtl (5 bf 5) [45/=/5?44 451791=3 DL\

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Jblh  Erbwsh  Whdrgj  Wuesgriptibns  Jhp 

Gitdtibn

Whdrgj1

Vb. _dch/

 Drtigh

 

 D_W »Aburnds »_jys. Uhv. H »

Vbulh 67 »Issuh 8

0 _rhvibus Drtigh |Nhxt Drtigh >

_jys. Uhv. H 67, ?849?: (5??4) [:

pdchs\

Gbmbn mistrieutibns in

MND

Destrdgt Uhfhrhnghs

_jys. Uhv. H 67, ?849?: (5??4)1 Gbmbn mistrieutibns in MND 

GitincDrtig`hs(=)

 

Dlhrigdn _jysigd` Wbgihty 

@bc in  | Grhdth Dggbunt (wjdt's 

tjis2)

UWW Fhhms  | Hldi Dhrts 

_jys. Uhv. @htt.

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_jys. Uhv. H 67, ?849?: (5??4)1 Gbmbn mistrieutibns in MND 

 Dpri 5??4

]jh gbmbns, 6= in nulehr, drh mistrieuthm bvhr tjh gbminc pdrts bf

MND shquhnghs. ]jh mistrieutibn fungtibn is tjh pbt bf frhquhngy

vhrsus rdnk bf tjh gbmbns. ]jhsh mistrieutibns drh gjdrdgthrizhm ey

pdrdlhthrs tjdt drh d`lbst univhrsd, i.h., chnh inmhphnmhnt. ]jhrh

is eut d sld` pdrt tjdt mhphnms bn tjh chnh. Sh prhshnt tjh tjhbry

tb gdgudth tjh univhrsd (chnh-inmhphnmhnt) pdrt. ]jh pdrt tjdt is

chnh-sphgifig, jbwhvhr, jds unmhthrlinhm bvhrdps dnm fugtudtibns.

© 5??4 ]jh Dlhrigdn _jysigd Wbgihty

XU@1

jttp1//ink.dps.brc/mbi/4?.44?7/_jysUhvH.67.?849?:MBI1

4?.44?7/_jysUhvH.67.?849?:

_DGW1

:3.4?.+h, :3.48.-v, ?8.=?.-d, 35.3?.+l

*Hldi dmmrhss1 tpdsOldjhnmrd.idgs.rhs.in†Hldi dmmrhss1 tpsgOldjhnmrd.idgs.rhs.in

‡Hldi dmmrhss1 tpagOldjhnmrd.idgs.rhs.in§Hldi dmmrhss1 ednmybOisigd.dg.in

  0 _rhvibus Drtigh |Nhxt Drtigh >

Fbgus1 Dnbtjhr Wthp Edgk fbr Sdvh-_drtig`h 

Mud`ity 

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_jys. Uhv. H 67, ?849?: (5??4)1 Gbmbn mistrieutibns in MND 

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@INCXIW] @ist - _dphr Mhtdi`s

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@INCXIW] @ist - _dphr Mhtdi`s

◂ Wuelit  ◂ With Ldp  ◂  Dmvdnghm Whdrgj  ◂ Uhdm @INCXIW] ◂

◂ Uhvihwhr @bcin ◂

@INCXIW] @ist > _ue`igdtibns > Dgdmhlig _dphrs > _dphr Mhtdi`s

❌ Debut Xs 

❌ @INCXIW] Wtdff  

❌ @INCXIW] @ist 

❌ @INCXIW] _rbahgts 

❌ Abes 

❌ Gbnfhrhnghs 

❌ _ue`igdtibns 

❌ Dmvdnghm Whdrgj 

❌ _hbp`h & _rbcrdls 

❌ She @inks 

❌ Ldi`inc @ists 

❌ Dsk d Tuhstibn 

❌ Dumib dnm Vimhb 

◂ MBND]H 

_ue`isjinc _drtnhr1

_ue`isjhr @bcin 

fi`h1///G|/Mbgulhnts%5?dnm%5?Whttincs/MHEX/Mhsktbp/erbwsh-pdphrs-dgtibn.gfl.jtl (4 bf 7) [45/=/5?44 4518?146 DL\

Cb

@INCXIW] @ist - _dphr Mhtdi`s

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@INCXIW] @ist _dphr Mhtdi`s

 Dgdmhlig _dphr

]it`h1 Gbmbn Mistrieutibns in MND

_dphr XU@1 jttp1//drxiv.brc/des/pjysigs/?4?5?54  Dutjbr1 W. Gjdttbpdmjydy 

Hldi`1 g`igk jhrh tb dgghss hldi` 

 Dutjbr1 A. Gjdkrdedrti 

Hldi`1 g`igk jhrh tb dgghss hldi` 

 Dutjbr1 Mhedprdsdm Ednmybpdmjydy 

Hldi`1 g`igk jhrh tb dgghss hldi` 

Jblhpdch1 jttp1//isim.dgdmhlid.hmu/MhedprdsdmEdnmybpdmjydy 

Institutibn1 Inmidn Wtdtistigd` Instituth

@incuistig Fih`m1 Misgip`inh bf @incuistigs

 Destrdgt1 ]jh syleb`ig shquhnghs bf tjh hxbns tjdt ldkh juldn prbthins drh sueahgthm tb lhtjbms bf stdtistigd`

`incuistigs. ]jh imhds mhvh`bphm fbr tjh ndturd` `dncudchs ey C.K. Qipf, wjhn dpp`ihm tb tjhsh shquhnghs,

sjbw d sicnifigdnt prblish. In _drtigu`dr, wh drcuh, ]jh Qipf's hxpbnhnt miffhrhntidth, dnm jhngh, imhntifihs

mispdrdth juldn shquhnghs. ]jh gbmbns, 6= in nulehr, drh mistrieuthm bvhr tjh gbminc pdrt bf MND

shquhnghs. Lhtdpjbrigd``y sphdkinc, tjh shquhnghs d`lbst rhshle`hs `incuistig strugturh. ]jh mistrieutibn

fungtibn is tjh p`bt bf frhquhngy vhrsus rdnk bf tjh gbmbns. ]jhsh mistrieutibns drh gjdrdgthrizhm ey

pdrdlhthrs tjdt drh d`lbst univhrsd`, i.h., chnh inmhphnmhnt. Dutjbrs (D, Wbl, W.Gjdttbpdmjydy, A.

Gjdkrbedrti dnm Mhedprdsdm Ednmybdpmjydy) prhshnt tjh tjhbry tb gd`gu`dth tjh univhrsd` (chnh

inmhphnmhnt) witj tjh jh`p bf `incuistig tjhbry. ]jh pdrt tjdt is chnh sphgifig, jbwhvhr jds unmhthrlinhm

bvhr`dps dnm f`ugtudtibns.

]yph1 Gb``hgtibn

Wtdtus1 Gblp`hthm

Vhnuh1 Inmidn Dssbgidtibn fbr Gu`tivdtibn bf Wgihngh, Kb`kdtd

_ue`igdtibn Infb1 _jysigd` Uhvihw H, Vb`. 67, issuh 8, ?849?:(pp.?849?:-4- ?849?:-:). X.W.D.

XU@1 jttp1//drxiv.brc/des/pjysigs/?4?5?54 

Edgk 

 Dmm d nhw pdphr  

Uhturn tb Dgdmhlig _dphrs ldin pdch 

Uhturn tb Mirhgtbry bf @incuists ldin pdch 

fi`h1///G|/Mbgulhnts%5?dnm%5?Whttincs/MHEX/Mhsktbp/erbwsh-pdphrs-dgtibn.gfl.jtl (5 bf 7) [45/=/5?44 4518?146 DL\

@INCXIW] @ist - _dphr Mhtdi`s

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@INCXIW] @ist _dphr Mhtdi`s

 Debut @INCXIW]  | Gbntdgt Xs  | Uhpbrt Erbkhn @ink 

Sji`h tjh @INCXIW] @ist ldkhs hvhry hffbrt tb hnsurh tjh incuistig rh`hvdngh bf siths isthm bn its

pdchs, it gdnnbt vbugj fbr tjhir gbnthnts. 

fi` ///G|/M t %5? m%5?W tti /MHEX/M kt /e ti f jt (7 f 7) [45/=/5?44 45 8? 46 DL\