connective tissue fibers dr iram tassaduq connective tissue fibers formed by proteins three types of...
TRANSCRIPT
CONNECTIVE TISSUE FIBERS
Dr Iram Tassaduq
CONNECTIVE TISSUE FIBERS
Formed by proteins Three types of fibers Collagen Elastic Reticular Uneven distribution
COLLAGEN FIBERS Most abundant type
of C.T. fibers May be collected
together to form a bundle of greater size
Straight or slightly wavy course of fibers
Loosely or densely packed fibers
Staining
TYPES OF COLLAGEN
TYPES OF COLLAGEN
RETICULAR FIBERS Rete is a latin word
which means net 0.5—2 um in diameter Composed of type III
collagen Provide supporting
frame work Occurs as fine network
around small blood vessels, muscle fibers, nerve fibers and lymphoid organs
Not distinguishable in ordinary H&E staining due to their thinness.
o Can be visualized with PAS staining, seen as red strands by due to presence of carbohydrates
Called argyrophilic fibers because of their high affinity for silver salts.
ELASTIC FIBERS
Typically thinner than collagen fibers
Arranged in branching pattern to form a three dimensional network
Interwoven with collagen fibers
Provide tissue with ability to respond to stretch and distension
ELASTIC FIBERS Composed of two
structural components Elastin Fibrillin 1 Elastic property of elastin
molecules is related to its unusual polypeptide backbone that causes random coiling
Elastic material is a major extra cellular substance in vertebral ligaments, larynx & elastic arteries
TYPES OF INTERCELLULAR SUBSTANCE
Amorphous
Fibrous
Glycosaminoglycans
Glycoproteins
Collagen FibersElastic Fibers
Reticular fibers
GLYCOSAMINOGLYCANS
Polysaccharides containing amino sugar
Secretion products of C.T. cells especially fibroblasts
Stain with basic dyes Exhibit metachromasia
GLYCOPROTEINS Proteins with one or more heterosaccharide
chains containing hexosamine, galactose, & other sugars
These include:FibronectinLamininTenascinOsteopontin
TYPES OF CONNECTIVE
TISSUE
MESENCHYMAL CONNECTIVE TISSUE
oMesenchyme forms the undifferentiated "filling" of the early embryo.o It consists of mesenchymal cells, which interconnect by slender cell processes. oMesenchymal cells have stem cell properties, i.e. they are able give rise to other cell and tissues types.
MESENCHYME
MUCOUS CONNECTIVE TISSUE
oIt contain a large amount of ground substance. o Found in the umbilical cord (Wharton's jelly) and in embryonic tissues.
MUCOUS CONNECTIVE TISSUE
LOOSE AREOLAR CONNECTIVE TISSUE
Widely distributed Provide supporting
framework Acts as embedding
medium for blood vessels and nerves
LOOSE AREOLAR CONNECTIVE TISSUE
RETICULAR CONNECTIVE TISSUE
Consist of reticular cells and fibers
Cells are stellate shape
Form stroma of liver,spleen and bone marrow
DENSE IRREGULAR CONNECTIVE TISSUE
DENSE REGULAR CONNECTIVE TISSUE
ADIPOSE TISSUE