ctech labs by warsito p. taruno
TRANSCRIPT
BUILDING TECHNOLOGY
COMPANY IN INDONESIA EXPERIENCES IN DEVELOPING AND
COMMERCIALIZING ECVT & ECCT TECHNOLOGIES
FOR CANCER DIAGNOSIS & THERAPY
DEN HAAG, THE NETHERLANDS
14 SEPT 2013
WARSITO P TARUNO
The Engine of Tomorrow
CTECH LABS EDWAR TECHNOLOGY
CTECH LABS EDWAR TECHNOLOGY
TERMINOLOGI ECVT (ELECTRICAL
CAPACITANCE VOLUME TOMOGRAPHY):
4D TOMOGRAPHY UNTUK
APLIKASI INDUSTRI DAN MEDIS
ECCT (ELECTRO-
CAPACITIVE CANCER THERAPY):
Terapi Kanker berbasis
gelombang listrik bertenaga sangat lemah dalam bentuk peralatan baju listrik
The Milestones B
S R
esea
rch
sta
rt: U
S S
enso
r fo
r 3-
ph
ase
rea
cto
r in
stru
men
tati
on
Wo
rld
’s F
irst
US
To
mo
gra
ph
y fo
r 3-
Ph
ase
Rea
cto
r Im
agin
g
Wo
rld
’s F
irst
US
Tec
hn
iqu
e f
or
3-P
has
e R
eact
or
Mea
sure
men
t
Cap
acit
ive
Tom
og
rap
hy
for
real
ti
me
3-P
has
e R
eact
or
Imag
ing
Imag
e R
eco
nst
ruct
ion
Alg
ori
thm
fo
r Cap
acit
ive
Tom
og
rap
hy
Pat
ent
Gra
nte
d
4D
Ele
ctri
cal C
apac
itan
ce
Vo
lum
e To
mo
gra
ph
y (E
CV
T) P
aten
t G
ran
ted
Fir
st G
ener
atio
n E
CV
T S
yste
m
(DA
S);
S
ON
AC
TX
fo
r CN
G C
ylin
der
S
can
ner
Dev
elo
pe
d
2.5
Gen
erat
ion
EC
VT
Sys
tem
(D
AS
)
Wo
rld
’s F
irst
4D
EC
VT
Bra
in
Act
ivit
y S
can
ner
E
lect
ro C
apac
itiv
e C
ance
r T
her
apy
(EC
CT
) In
ven
ted
; W
orl
d’s
Fir
st E
CV
T B
reas
t C
ance
r S
can
ner
Shizuoka University, JPN Ohio State University, US
CTECH Laboratories The Center for Tomography Research
EDWAR TECHNOLOGY
Technology Users: Ohio State University (USA), NASA, Univ. of Cambridge
(UK); B&W (USA); US DoE; BBG (INA), National Univ. of Malaysia, Univ. of Malaya (MLY), KAU (KSA)
1992 1997 1999 2001 2003 2006 2008 2009 2010 2012
Principle of ECVT STEP 1: Capacitance measurement
STEP 2: Reconstructing 3D permittivity distribution
E
V
V
ECVT system consists of sensor system, data acquisition system
and computer system for control, image reconstruction and display
d
VC
nE ˆ
PCT, WO 2006/102388 (Warsito et al.,2006)
US PTO 6577700 (Warsito & Fan,
2003)
CTECH LABS EDWAR TECHNOLOGY
Industrial Scale Applications
Realtime 3D (4D) image of industrial reactor
B&W Project, Akron, OH, USA
ECVT Imaging of spray column of water-solid catalysts system I.D. = 5ft (1.65m)
CTECH LABS EDWAR TECHNOLOGY
ECVT Applications: ECVT vs. Super Computer Simulation
US Dept of Energy Project on Advanced Research to Support Development of Next-Generation Power Plants
ECVT (Real)
Super Computer (Simulation)
CTECH LABS EDWAR TECHNOLOGY
DoE Project
Simulation vs. ECVT
ECVT Brain Function 2010—
Functional ECVT 4D Brain Activity
32-electrode Brain Scanner ECVT System
4D Brain Activity Map
ECVT has been successfully applied to monitor activity of human brain during different stimulations. Electrical signals measured from capacitance electrodes showed significant differences when the brain is in rest and in high task. The ECVT generates real time and volumetric image of the human brain during the activity. The system helps scientists to study the human brain activity, and possibly detect abnormalities in the human brain.
Electrical signal
monitoring of human brain
during different
stimulations
Snapshot of real-time volumetric images of human brain activity during stimulations
32-electrode Brain Scanner ECVT Sensor
4D Scanner of Human Brain Activity WORLD’S FIRST CTECH LABS EDWAR TECHNOLOGY
ECVT vs. PET-CT ECVT vs. MRI
12/3/13
19/3/13
CASE: AMNESIA Kaki lumpuh, didorong dengan kursi roda, komunikasi sedikit masih bisa; MRI tak terdeteksi kelainan.
CASE: AMNESIA Kaki sedikit membaik, komunikasi sama-sekali hampir ‘blank’.
Fungsi motorik lemah
Fungsi Bahasa lemah
CASE: Amnesia
MRI (3/3/13): Tak terdeteksi abnormalitas
ECVT Breast Cancer 2011—
ECVT for Breast Scanner CTECH LABS EDWAR TECHNOLOGY
WORLD’S FIRST
4D BREAST CANCER SCANNER
ECVT
ECVT
Benign Tumor
Malignant Cancer Mammography
Mammography
MRI 3T
MRI 3T
A. Breast with early cancerous mass
development
B. Breast with significant cancerous mass
C. Normal Breast
CTECH LABS EDWAR TECHNOLOGY
ECVT vs. Mammography (Malignant Cancers)
ECVT vs. Mammography (Benign Tumors)
Comparisons of PET-CT Image and ECVT Image of Breast Cancer
ECVT Image
PET-CT Image
CTECH LABS EDWAR TECHNOLOGY
ECCT Electro Capacitive Cancer Therapy
2010–
ECCT (Electro-Capacitive Cancer Therapy): Converting Poisson’s equation into fashion for cancer therapy
CTECH LABS EDWAR TECHNOLOGY
What difference with Kirson & Palti Method?
ECCT
Capacitive
Completely Non-contact
Penetrating through air layers
Low voltages (<30V)
Good for lung and colon-rectum CA and working to almost all type of cancers including lymphoma and leukemia
NovaCure
Quasi-Electrostatic (quasi-conductive)
Using high-conductive ceramic electrodes with direct contact to skin
No-air layer permitted
High voltages (>50V)
Not possible for air-contact cancerous mass (in fact work only to brain cancer)
NovaCure
Computation
Fashion Electronics
ECCT APPAREL
WIRED & COMPUTED SUIT
po
CTECH LABS EDWAR TECHNOLOGY
-
-
-
-
- -
- +
+
+
+
+ +
+
Research on effect of electrical field on cancer cell growths (High voltage, using quasi-conductive electrode)
- Electrical field inhibiting cell growth (A)
- Splitting cell destroyed under electrical field (B,C)
CTECH LABS EDWAR TECHNOLOGY
Effect of electrical field to breast cancer cell MCF-7
Effect of electrical field to Fibroblast Vero Cell
CTECH LABS EDWAR TECHNOLOGY
A. Before ECCT Therapy; B. 1 Month after ECCT
Therapy; C. 1.5 Month after ECCT
Therapy
A
B C
CTECH LABS EDWAR TECHNOLOGY Progress of Breast Cancer Mass with ECCT imaged by ECVT
Before Therapy
After 2 Months of ECCT Therapy (PET-CT)
After ECCT Therapy (ECVT Image)
FDG Activities of Breast
Cancer
IMAGE of Breast Cancer Before and after ECCT Treatment
Innovation Thresholds: Being able of making a thing DOES NOT guarantee a business
Basic research
& technology
development,
research project,
limited production
of highly
customized
products
Product
development
(R&D),
Manufacturing
and distribution
Activity
End user/
customer service
based business
RESEARCH PRODUCT
MANUFACTURING BUSINESS
Free
Imagination,
Serendipity QA & Delivery
Known Risks,
Effective Strategy,
Timely Decision
DIS
CIP
LIN
ED M
IND
CH
ALL
EN
GIN
G M
IND
Research/
Technology
Development
Cycles
Product
Development
/Production
Cycles
Product
utilization/
Business
Cycles
RESEARCH MANUFACTURING BUSINESS/
UTILIZATION
BUILDING INNOVATION CAPACITY IN SME
EDWAR
TECHNOLOGY CTECH
Laboratories
Open Innovation Strategic
Partnership Business
Alliance
1. NETWORKING
1. International links to global value change is crucial
2. Active interaction with users (industries) to learn demand/market
2. RESOURCES: 1. State of Mind: Strong motivation
2. Basic infrastructure: Computer, internet, workshop, access to knowledge sources such as digital library.
3. Basic financial: salary for full-time staffs (24/7)
3. INSTITUTION
1. Institutional legal for receiving PO
International Scientific
Forum
International Industrial Linkage
Basic Infrastructure
Basic Financial Support
Legal formal, venture capital
CLOSURE
Open innovation and strategic partnership provide benefit for SMEs to upgrade its capacity in innovation, but the cooperation must stem from supply and demand relationship (win-win solution), otherwise it will not work.
Technology development and utilization/commercialization must continue in parallel, otherwise the innovation will not sustain.
Technology business requires a completely different state of mind, i.e. taking risk, which usually researchers do not have; researchers need partners to commercialize their technology.
Funding is not always an issue for a researcher to innovate, but cooperation is.