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Jeddah, Saudi Arabia

Curriculum Vitae

Prof. Waseem Ahmad (Faridi) Ph. D

Aligarh Muslim University King Abdulaziz University Division of Genetics Department of Zoology Aligarh

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(فريمي) وسي أأحم . د.أ جامع وساسع عل رر

C u r r i c u l u m V i t a e

Personal Details

Prof. Waseem Ahmad (Faridi) Division of Genetics, Department of Zoology Aligarh Muslim University, Aligarh, UP, India Email: waseemahmad2007@hotmail.com Date of Birth: 16 August 1952 (Male, Married) Passport No.: K1143740

Career Profile

Dr. Waseem Ahmad (Faridi) is a permanent faculty; a Professor of Genetics and Molecular Biology in the Faculty of Life Science, Department of Zoology, Aligarh Muslim University, Aligarh (UP); has a wide experience of teaching and research nationally and internationally. He has also worked in Saudi Arabia and Asmara in various capacities. His work on Molecular Genotoxicity and Genomic Medicine is evidenced by many awards, grants and research papers in the peer reviewed journals of national and international repute. He has also acted as consultant to many research organizations and authored many books. Recently he authored a book on ‘Genetics and Genomics’ for Pearson Publication Incorporation.

Educational Qualifications

1980 Ph.D (Doctor of Philosophy) Aligarh Muslim University (AMU), Aligarh, India. Genetics, Life Sciences/ Zoology

Title of Thesis : Genetic studies on morphological variability in Culex pipiens fatigans

1978 M.Phil (Master of Philosophy) Aligarh Muslim University, Aligarh, India. Genetics and Cytogenetics, Life Science/Zoology Title of Thesis : Genetic studies of Mosquitoes

1975 M.Sc (Master of Science)

Aligarh Muslim University, Aligarh, India. Genetics and Cytogenetics, Life Science/Zoology

1973 B.Sc. (Bachelor of Science) Guru Nanak Dev University, Amritsar, India. Zoology, Botany, Chemistry, English

1979 Diploma in Statistics

Department of Statistics, Aligarh Muslim University, Aligarh, India

1978 Diploma in French

Department of Linguistics, Aligarh Muslim University, Aligarh, India

1977 Certificate in French

Department of Linguistics, Aligarh Muslim University, Aligarh, India

Positions

Current (Permanent)

India

Professor of Genetics / Molecular Biology/Life Science (Zoology) Division of Genetics (and Molecular Biology), Department of Zoology, Aligarh Muslim University (AMU), Aligarh - 202002,

UP, India.

Previous

Saudi Arabia Professor of Biology

Faculty of Biological Science, King Abdulaziz University (KAU), Jeddah, KSA

Consultant Research, Center of Excellence in Genomic Medicine Research (CEGMR), King Fahd Medical Research Centre (KFMRC), King Abdulaziz University (KAU), Jeddah, Saudi Arabia

Professor of Medical Biology College of Medicine, Faculty of Medicine King Abdulaziz University (KAU), Jeddah, Saudi Arabia

Asmara

Professor of Biology and Head of Biology Department, Eritrea Institute of Science and Technology (EIT), Asmara

Address (India, permanent) at present (2014)

AB- 55, Medical Enclave, Aligarh Muslim University, Aligarh - 202002, UP, India Phone : 0091-571-2720920 Mobile : 0091- 9457155169 , 0534010549 Email : waseemahmad2007@hotmail.com

بسي هللا لرأحجن لرأسي

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ABSTRACT: MS/Thesis, Ph.D Dissertation & Post doctorate Research

Mosquitoes being vectors of many diseases and have great potential for human

exposure, the doctoral work taken therefore. The sentinel genetic potential was

harnessed with an aim to contribute in mosquito controlling programmes. The

seasonal variations of different genera of mosquitoes, epidemiology of certain

diseases, new mutants, and the problems with respect to some agricultural

pesticides were done. To begin with, immature stages of various genera was

determined. The population of Culex was found to be constantly higher than Aedes

and Anopheles. The work was extended to study the epidemiological studies and

incidence of malaria and other mosquito borne diseases at different seasons. The

disease index for malaria was significantly higher in younger group with a gender

bias.

The populations showed great genetic plasticity. Mutations affecting structural

modifications of various organs were isolated. Thus, hb, ra, ab, bg, bs and bi were

analyzed for inheritance pattern, frequency distribution and test statistics (crs).

Linkage group study was made with respect to lp4 gene. The origin of

gynandromorphism (sgm, gm) on the basis of bi-nucleated eggs bearing an m

factor and independently fertilized by male gametes of M and m genotype was

postulated.

In addition, a comprehensive assessment of potential hazards of chlorinated

phenoxy compounds (2,4-D, PCP, 2,4,5-T) was embarked upon. Principal objective

of the study was to assess the mutagenic activity using wide range of end point

parameters. Anti-mutagenic studies for repairing the chromosomal and DNA

damage by plant extract showed promising results. Comparative studies were

made with many mutagens. Electromagnetic radiations, including full solar eclipse

radiations were subjected to test for making sterile release program possible in

controlling the mosquito species. Some mutants discovered during the course of

study such as d and bb being lethal genes, showed a great potential for restricting

these vectors. In addition, predation behavior of Culex (Lutzia) raptor larvae on the

aquatic stages of Culex , Aedes and Anopheles showed a great promise in

biological control.

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Distinctions and Awards

2013 Chaired and participated in deliberations of National Conference on Insect Diversity and Systematics: Special Emphasis on Molecular Approaches, 28-30 Oct., 2013, organized by Dept. of Science and Technology, University Grants Commission, Govt. of India and Department of Zoology, AMU, Aligarh.

2012 Chairperson Nat. Symp. Emerging Trends in Biological Sciences: special emphasis on neurosciences, org.

Interdiscip. Brain Res. Cent. (IBRC), Faculty of Med. AMU, 24 – 25 Sept. 2012.

2011-14 Member Professor on panel Faculty of Life Sciences, AMU, Aligarh

2011 Chaired the INSPIRE award program, DIET under Ministry of Science and Technology, Govt. of India, Srinagar,

Kashmir.

2010 Chaired session in annual symposium on Frontiers in Life Sciences: Basic and applied, Oct. 23-24 2010, organized by Muslim Association for Advancement of Science, MAASCON-I, Dept. of Zoology, AMU, Aligarh.

2009 Member Board of Studies, Department of Biological Sciences, King Abdulaziz University, KAU, Jeddah.

2006-09 Research Consultant, Genomic Medicine Unit and Center of Excellence in Genomic Medicine Research, KFMRC, KAU, Jeddah.

2008-09 Member Executive Board, Center of Excellence in Genomic Medicine Research (CEGMR), King Fahd Medical

Research Center (KFMRC), King Abdulaziz University, Jeddah.

2006-09 Member on the panel of Evaluator International Research Projects, Center of Excellence in Genomic Medicine

Research.

2006-09 Member Board of Studies, College of Medicine, King Abdulaziz University, Jeddah

2009 Facilitated by the Faculty of Medicine, King Abdulaziz University, Jeddah.

2008 Facilitated on First Annual Genomic Day Conference, Center of Excellence in Genomic Medicine Research,

(CEGMR; KFMRC), Jeddah.

2007 Moderated and chaired session on the Environmental Genomic Research Program Committee in

International Workshop on the Introduction of Centre of Excellence in Genomic Researches (CEGMR) at King Fahd Medical Research Centre, King Abdulaziz University, Jeddah.

2002-04 Member Executive Counsel, Eritrea Institute of Science and Technology (EIT), Asmara.

2002-04 Founder Member and Head of Department of Biology, EIT, Asmara.

2002 Discussant ‘Road to Dolly and path ahead’, Nat. Sem. On Cont. Issues in Bioethics, Feb. 5 – 7, 2002, organized by Ind. Coun. Phil. Res., New Delhi and Dept. of Phil., AMU.

2002 Coordinator LXXIV Orientation Program of UGC Academic Staff College, AMU from April 10 to May 7, 2002.

2000 Nominated as the International Man of the Year 1999-2000, for the contribution in research, Science and Education by the International Biographical Centre, Cambridge, England.

2000 Conferred Membership, Research Board of Advisors 2000 of the American Biographical Institute, USA.

2000 Member, New York Academy of Sciences, New York.

1982-83 Awarded Post Doctoral Fellowship by Council of Scientific and Industrial Research, CSIR, New Delhi, India (No.

7/112/919/81/EMR-1).

1985 Awarded Research Associateship by Council of Scientific and Industrial Research, CSIR, New Delhi, India (No. 9/112 (62)/ /84/EMR-1).

1976-80 Awarded Senior Research Fellowship and Junior Research Fellowships by Council of Scientific and Industrial

Research, CSIR, New Delhi, India for Doctorate.

Peer Reviewed Publications Citation Indices Citations : All 411, (since 2009: 268) H - index : All 8, (since 2009: 8) i 10 - index : All 8, (since 2009: 7) 2014 Mitodepressive and mild genotoxic effect of Dichlorvos (DCV) in bone marrow cells of Rattus norvegicus: An

in vivo observation (Under communication : MUATGEN-S- 14-0035)

2014 Oxidative damage and cytoarchitechtural assessment of dimethoate intoxication on rat liver and kidney: An

in vivo study. Nazia Nazam, Mohammad Iqbal Lone, Monika Sharma, Aijaz A khan, Riaz Ahmad, Abdelhakim M Kelany, Waseem Ahmad. Manuscript ID: Tox-14-269 (Under Review: Environ Toxicol).

2014 Combined In Silico and In Vivo Studies Shed Insights into the Acute Acetylcholinesterase Response in rat and

human brain". Nazam N., Shaikh S., Lone M. I., Sharma M., Ahmad Waseem, Biotechnology and Applied Biochemistry. (doi/10.1002/bab. 1275/pdf).

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2014 Protective effects of Quercetin against Dimethoate – induced cytotoxicity and genotoxicity in Allium sativum

test. Waseem Ahmad, Sheikh S., Nazam N. and Lone M. I.; Int. Sch. Res. Notices, ISRN Botany 2014, Vol.2014, 6 pages , Article ID 632672, 2014.

2013 Genotoxicity of an organochlorine pesticide dichlorophene by micronucleus and chromosomal aberration

assays using bone marrow cells of Rattus norvegicus. Mohammad Iqbal Lone, Nazia Nazam, Sibhghatulla Shaikh and Waseem Ahmad. Caryologia: International Journal of Cytology, Cytosystematics and Cytogenetics, 2013 Vol. 66 (4) 296–303, 2013 (IF 0.632)

2013 Assessment of the genotoxic potential of the insecticide Dichlorvos using cytogenetic assays. Nazam N., Lone M. I., Sheikh S. and Waseem Ahmad. Interdisc. Toxicol. 6 (2), 77-82, 2013 (Citation 1)

2012 Evidence of Apoptosis in some cell types due to Pentachlorophenol (PCP) in Heteropneustes fossilis. Ali M. N.,

Nazam N., Lone M. I., Sheikh S., and Waseem Ahmad. Saudi J of Biological Sciences, Elsivier, 2012.

2012 Dichlorophen and Dichlorovos mediated genotoxic and cytotoxic assessment on root meristem of Allium

cepa. Sheikh S, Nazam N, lone M I and Waseem Ahmad. Sci.Diliman, 24, (1), 13-22, 2012 (Citation 2).

2011 Analysis of serum proteins and enzyme levels in human subjects with osteoarthritis. Ahmad A, Irshad M,

Waseem Ahmad, Khan A Q, Ahmad R, J Med. Biochem. 30 (1): 15-24, 2011 (Citation 2, IF 1.084)

2011 Environmental, Maternal and Cytogenetic Analysis of live born infants with Down’s syndrome. Qahtani M.H., (Faridi) Waseem Ahmad., Iqbal L.M., Nazia N., Riaz A., J. US-China Med. Sciences, 8 (3)143 - 149, 2011.

2010 Frequency of Mediterranean mutation among a group of Saudi G6PD patients in Western region – Jeddah.

Gari M. A., Choudhary A. G., Al Qahtani M. H., Abuzenadah A. M., Waseem Ahmad, Banni H., Al Sayes F.M., Al Harbi A. and Lary S., Int. Jnl. Lab. Hem. 32,17-21, 2010 (Citation 8, IF 1.293).

2008 Detection of FLT3 oncogene mutations in Acute Myeloid Leukaemia using Conformation Sensitive Gel

electrophoresis. Gari M., Abuzenadah A., Choudhary A., Al Qahtani M., Banni H., Waseem Ahmad, Al Sayes F, Lary S., and Damanhouri G., Int. Jnl. Mol. Sci., 9,2194-2204; 2008 (Citation 6, IF 2.646).

2006 Micronuclei induction and chromosomal aberrations in Rattus norvegicus by chloroacetic acid and chlorobenzene. Siddiqui, M.F., Ahmad R, Waseem Ahmad and Hasnain A. Ecotoxico. and Environ. Safety, 65, 159-164, 2006 (Citation 4, IF 2.572).

2006 Evidence of Apoptotic effects of 2, 4-D and butachlor on walking Catfish Clarias batrachus by Transmisssion Electron microscopy and DNA degradation studies. Ateeq B, Farah M.A., Waseem Ahmad life Sciences 78(9) 977-986, 2006 (Citation 30, IF 2.555).

2006 Antimutagenic effect of neem leaves extract in freshwater fish, Channa punctatus eavaluated by cytogenetic

tests. Farah M.A., Ateeq B. and Waseem Ahmad. Science of Total Environment (STOTEN )364(1), 200-214, Elsevier, 2006 (Citation 22, IF 3.258).

2005 Micronuclei induction and aberrations in Rattus norvegicus by chloroacetic acid and chlorobenzene. Siddiqui

M. F., Ahmad R., Waseem Ahmad, Science of Total Environment, 2005 (Citation 5).

2005 Detection of DNA damage by alkaline single cell gel eletrophoresis in 2,4-D and Butachlor exposed

erythrocytes of Clarias batarachus. Ateeq, B., Farah M.A. and Waseem Ahmad. Ecotoxocology and Environmental Safety, Elsevier, 62(3), 348-354,2005 (Citation 46, IF 2.572)

2005 Blood: A risky stream to HIV infection, Waseem Ahmad, Eritrea Profile, 2005.

2005 Pentachlorophenol mediated apoptosis in germinal epithelium and renal cells of Heteropneustes fossilis. Ali,

M. N., Waseem Ahmad, Farah, M. A. and Ateeq B. Mutagenesis, 2005 (IF 3.5).

2004 Studies on lethal concentrations and toxicity stress of some xenobiotics in aquatic organisms. Farah, M. A.,

Ateeq, B., Ali, M. N.,Rubina, S. and Waseem Ahmad. Chemosphere, Elsevier, 55,257-265, 2004 (Citation 52, IF 3.137).

2004 AIDS: Need to know and inform others, Raza M. A. and Waseem Ahmad, Eritrea profile, Nov. 27, 2004.

2003 Evaluation of genotoxicity of PCP and 2,4-D by micronucleus test in freshwater fish Channa punctatus. Farah,

M. A., Ateeq, B., Ali M. N., Waseem Ahmad. Ecotoxicology and Environmental Safety, (Academic Press) 54, 25-29, 2003 (Citation 40, IF 2.572).

2003 Antimutagenic effect of neem leaves extract in freshwater fish, Channa punctatus eavaluated by cytogenetic tests. Farah M.A., Ateeq B., Ali M. N. and Waseem Ahmad.Intdis. App. Zoolo.Res., pp73, 2003 (Citation 22).

2002 Induction of micronuclei and erythrocyte alterations in the catfish Clarias batrachus by 2,4-

dichlorophenoxyacetic acid and butachlor. Ateeq, B., Farah, M. A., Ali, M. N. and Waseem Ahmad., Mutation. Research., (Elseveir) 518, 135-144, 2002 (Citation 75, IF 3.603).

2002 Clastogenicity of pentachlorophenol, 2,4-D and butachlor evaluated by Allium root tip test. Ateeq B., Farah M.

A., Ali, M. N. and Waseem Ahmad., Mutation Research (Elsevier), 514, 105-113, 2002 (Citation 87, IF 3.603).

2002 Genotoxic effect of PCP and 2,4-D by micronucleus test in fresh water fish Channa punctatus, Ateeq B., Farah

M. A., Ali M. N., Waseem Ahmad., Published in 89th Conf. Intd. Sci. Congress, January 2002.

2002 Computerized automated morphometric assay including frequency estimation of pentachlorophenol induced

nuclear anomalies (micronucleus) in catfish Heteropneustes fossilis. Waseem Ahmad, Ali M.N., Farah M. A. and Ateeq B., Chromosoma, Springer – Verlag, 110(8), 570-574, 2002 (Citation 13, IF 3.340).

2002 'AIDS'. Waseem Ahmad, S. N. Hall Magazine, 2002.

2000 'AIDS'. Waseem Ahmad, Al-Habib, Hall Magazine, 110-117, 2000.

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1999 Histopathological effect of pentachlorophenol on a teleostean fish Hetero pneustes fossilis (Bloch): Light and

Transmission Electron Microscopic (TEM) studies of ovaries. Ateeq, B., Farah, M. A., Ali, M.N. and Waseem Ahmad. Toxicology & Environmental Health, 277-284, 1999 (IF 1.733).

1998 Effect of Pentachlorophenol on chromosomes of a catfish, Heteropneustes fossilis. Ali, M.N. and Waseem

Ahmad. Ind. J. Exp. Biol, 36(3), 304 - 307, 1998 (Citation 7, IF 1.195).

1996 A comprehensive assessment of potential hazards of chlorinated phenoxy compounds (2,4-D, PCP and 2,4,5 -T) in catfish (Heteropneustes fossilis): Chromosomal and Molecular genotoxicity. Waseem Ahmad and Ali, M.N., Chem. Env. Res. 5(1-4), 267-281, 1996 (IF 3.691).

1996 'AIDS: Clinical symptoms and latest state of research’ Waseem Ahmad, Bull. Soc. Prom. Edu & Sci , vol. 1, no 1,

P4, 1996.

1996 Genotoxicity of 2, 4-dichlorophenoxyaceticacid (2,4-D) on filarial vector, Culex pipiens fatigans. Ali, M.N. and Waseem Ahmad. J. Environ. Biol. 17 (4), 331-337, 1996 (Citation 1, IF 0.687).

1996 'Honey' Waseem Ahmad and Ahmad S., Bull. Soc. Prom. Edu. Sci. , New Delhi, Vol. 2, 6-7, 1996.

1994 Cytotoxic assay of 2,4-dichlorophenoxyaceticacid (2, 4-D) by mitotic index profiles in Culex pipiens fatignas. Waseem Ahmad and Ali, M.N., Bulletin de la Société Entmologique. 67, 169-175, 1994 (Citation 2, IF 0.537)

1994 Mutagenic activity of 2,4-dichlorophenoxyaceticacid (2,4-D) in the neuroblast micronucleus assay in Culex

pipiens fatigans. Ali, M.N. and Waseem Ahmad. Poll. Res. 13(2), 207-212, 1994.

1993 Mutagenic Assessment of 2, 4-D in Culex pipiens fatigans : Inheritance ,frequency distribution and test

statistics (Q) Of CRS mutants. Ali,M. N., and Waseem Ahmad ,Pollution research 12, 344, 1993.

1993 Studies on genetic and cytogenetic effects of full solar eclipse radiations in Culex pipens fatigans. Waseem

Ahmad, Int. J. Life Sci., 1993.

1993 2,4-D Induced mutants, inheritance and frequency estimates. Waseem Ahmad and Ali M. N., Int. J. Life Sci., 1993.

1992 Induced mutants in Culex pipens fatigans. Waseem Ahmad and Ali M. N., Int. J. of Life Sci., 1992.

1989 'What you are’ Waseem Ahmad, Health Era, Vol. 1(1), 59-61, 1989.

1989 'Human chromosomes’ Waseem Ahmad, Habib Hall Magazine, P17, 1989.

1989 Honey, A blessing, Ahmad S.M.S and Waseem Ahmad, Review of Religions (London), 9-23, 1989.

1989 Preliminary epidemiological studies of malaria in some parts of India. Ali, M.N. and Waseem Ahmad. J.

Environ. Res. 6 (1 - 2), 87-94, 1989.

1988 'Universe - Kainat: Tasveer-o-Tasawwar' - Waseem Ahmad, Science ki Duniya, Mishkat, 26-28, 1988.

1985 Genetic studies on gynandromorphism (sgm, gm) in Culex pipiens fatigans. Waseem Ahmad, Ara, A. and

Adhami, U.M., Experientia. 41(11), 1465-1467, 1985.(citation 4)

1984 Bulged eye, a new mutant in Culex pipiens fatigans. Waseem Ahmad, Ara, A. and Adhami, U.M., Japan. J. Sanit.

Zool. 35(2), 149-150, 1984.

1984 Genetic studies of bulged abdomen (BG) in male population of Culex pipiens fatigans. Waseem Ahmad, Ara A.

and Adhami, U.M., Ind. J. Herd. XIV (1-4), 32-36, 1984.

1983 Genetic studies on reduced antenna (ra) in Culex pipiens fatigans. Waseem Ahmad, Ara, A. and Adhami, U.M., J. Environ. Res. IV. (1- 2), 26-30, 1983.

1983 Genetics of Abnormal abdomen in Culex pipiens fatigans. Waseem Ahmad and Adhami, U.M., Ind. J. Exp. Biol.

21 (9), 511-512, 1983 (IF 1.195).

1983 Genetics of distorted (d) in Culex pipiens fatigans. Waseem Ahmad and Adhami, U.M., Bulletin de la Société

Entomologique. 56, 271-273, 1983.

1983 'Genetic Engineering' . Waseem Ahmad, Alig. Magz, 72-75, 1983.

1980 A new mutant head bristle (hb) in Culex pipiens fatigans. (Diptera :Culicidae) Waseem Ahmad and Adhami,

U.M., Ind. J. Zool. 8(1), 25-29, 1980.

1980 A new mutant black scale (bs) in Culex pipiens fatigans. Waseem Ahmad and Adhami, U.M, Proc. Sci, Tech. Ecosys. 84-89, 1980.

1979 Seasonal variation in the population of immature stages of two genera of mosquitoes at Aligarh. Waseem

Ahmad, Ara, M., Ali, Z. and Adhami, U.M., Sci. Environ. 1(2), 199-209, 1979.

1979 Inheritance of long palpi, a sex – limited mutation in Culex pipiens fatigans. Waseem Ahmad and Adhami,

U.M., Ind. J. Zool. 7(1), 1979.

1978 Predation of Culex (Lutzia) raptor larvae on the larvae of Anopheles and Culex species. Waseem Ahmad, Ara,

A. and Adhami, U.M., Ind. J. Env. Hlth. 20, 177-179, 1978.

1978 A new lethal mutation black band (bb) in Culex pipiens fatigans. (Diptera, Culicidae) Waseem Ahmad, Ara, A. and Adhami, U.M., Ind. J. Ent. 40 (21), 226-227, 1978 (IF 0.045).

Total Citation / Total Number of Publications (index c/p) : 411/60

Total Citation / Total Service Years (index c/s) : 411/30

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Total Citation in 2012 – 13 : 118

Published Abstracts, Conferences and Workshops

2014 Int. Conf. Future Prosp. of Adv. Biol. Sci. Hlth. Iss. & Env. Protect., Div. Biotech & Soc. Biosciences, Lucknow,

Hepato and Nephrotoxicity in Dimethoate intoxication in rat model, 7 – 8 Feb., 2014.

2014 Int. Conf. Future Prosp. of Adv. Biol. Sci. Hlth. Iss. & Env. Protect., Div. Biotech & Soc. Biosciences, Lucknow, Genotoxic potential of Nimesulide: An overview and future prospects, 7 – 8 Feb. 2014.

2013 International Symposium and Workshop on “The Control of Helminth Parasites with Emphasis on Liver Fluke

” & “Liver Fluke: An RNAi Workshop” , February 11-12, 2013.

2013 XXXVIIIth Annual Conference of Environmental Mutagen society of India & National Conference on “Current

Perspectives on Environmental Mutagenesis and Human Health”, January 28-30, 2013. Organized by BARC, EMSI, Mumbai (Three papers presented).

2012 National Symp. Emerg. Trends Biol. Sci.: Special emphasis on neuro science: Genetic instability in lymphoma

cell lines: An analysis of structural and numerical chromosome anomalies. Organized by Interdiscp. Brain Re. Cent. (IBRC), Faculty of Medicine, AMU, 24 – 25 Sep. 2012 (Two other papers).

2012 Silver Jubilee Symposium on “Emerging Trends in Biochemical and Toxicological Sciences”.In vivo

Genotoxicity of Dichlorophos in Hematopoietic Bone Marrow Micronucleus Test and Genotoxicity and Cytoxicity of Root meristem cells of Allium cepa induced by Dichlorophen March 6, 2012.

2010 Attended National Seminar on Spiritual Psychology; Oct. 28-29, 2010; Dept. of Psychology, AMU

2010 International Symposium on Mutagens and Genetic Diversity for Health and Agriculture, XXXVth Annual

Conference of Environmental Mutagen Society of India (EMSI); Evidence of Apoptosis in some cell types due to Pentachlorophenol(PCP) in Heteropneustes fossilis, March 12-14, 2010.

2010 International Symposium on Mutagens and Genetic Diversity for Health and Agriculture, XXXVth Annual

Conference of Environmental Mutagen Society of India (EMSI); Environmental, maternal and cytogenetic analysis of hereditary disorder – Downs syndrome, Mach 12-14, 2010.

2010 International symposium on the Role of Genomics in Clinical Practice, 35 th Annual Conference of the Indian

Society of Human Genetics, Dept of Genetics, SGPGIMS, Lucknow; FLT3 oncogene mutations in acute myeloid leukaemia analysed with the help of conformation sensitive gel electrophoresis, March 6-8, 2010.

2010 Int. Symp. Role Genomics in Clinic. Pract. & 35th Ann. Conf. Ind. Soc. Hum. Gent., Dept. of Genet., Post Grad.

Inst. Med. Sci. Lucknow; The feasibility of conformational sensitive gel electrophoresis in AML mutation screening, 2010.

2009 Workshop on launching of Princess Al - Jawhara Center of Excellence in research on Hereditary Disorders,

King Fahd Medical Research Center, King Abdulaziz University; Human hereditary disorders and their genetic basis, Faculty of Medicine, KAU, Jeddah, March 3, 2009.

2007 First Annual National Genomic Day Conference Center of Excellence in Genomic Medicine Research, CEGMR, King Fahd Medical Research Center,KFMRC, King Abdulaziz University, Jeddah, November 17, 2008.

2007 International Workshop on Introduction of Center of Excellence in Genomic Medicine Research at King Fahd Medical Research Center, Environmental Genomic Res., KFMRC, King Abdulaziz University, Jeddah, July 2, 2007.

2006 Second J & K Science Congress, DST, Govt. of India, University of Kashmir; Genotoxicity assay of

Pentachlorophenol using multiple testing protocols on catfish H. fossilis, 25 - 27 July, 2006.

2004 Workshop on Graduate Curricula and Research Areas, University of Asmara, Asmara, May 15 2004.

2003 National Seminar on Interdisciplinary Approaches in Zoological Research, Department of Zoology, University

of Kashmir, Srinagar, Antimutagenic effect of neem leaves extract (NE) in fresh water fishes, Channa punctatus, evaluated by chromosome aberration (CA) test., September 29 – October 1, 2003.

2002 The XXVI Env. Mut. Soc. Ind. (EMSI) Annual Conference, Induction of micronuclei in the peripheral blood

erythrocytes of catfish C. batrachus by 2-4 dichlorophenoxy acetic acid, 25 (1), 2002.

2002 National Seminar on Interdisciplinary Approaches in Zoological Research, Department of Zoology, University of Kashmir, Srinagar, Detection of DNA damage by Alkaline single cell gel electrophoresis in 2,4-D and Butachlor exposed erythrocytes of Clarias batrachus. , September 29 - October 1, 2003.

2002 Symposium on Environmental Genomics and Health Sciences and Annual Conference of Environmental Mutagens Society of India, Indian Toxicology and Research Center (ITRC) Lucknow, Pentachlorophenol mediated Apoptosis in germinal epithelium and kidney cells of Heteropneustes fossilis., March 19 - 21 2002.

2002 89th Conference of the Indian Science Congress, Genotoxic effects of PCP and 2,4-D by micronucleus test in

fresh water fish Channa punctatus., January 3-7 2002.

2002 National Symposium on Toxicology, Jamia Hamdard University, New Delhi, Histopathological effect of Pentachlorophenol on a teleostean fish Heteropneustes fossilis (Bloch): Light and Transmission Electron Microscopic (TEM) studies of ovaries. November 21 - 22, 2002.

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2001 The XXVI annual conference of Environmental Mutagens Society of India and the International Symposium on

Environmental Health Sciences in the 21st century. School of Life Sciences, Jawaharlal Nehru University, New Delhi, Induction of micronuclei in the peripheral blood erythrocytes of the catfish Clarias batrachus by 2,4- Dichlorophenoxyaceticacid and Butachlor. , March 5 – 7, 2001.

1996 Workshop on ‘Introduction to the use of personal computers in Bioinformatics with special reference to molecular modeling and protein folding’ sponsored by Dept. of Biotech., Ministry of Science and Technology, Govt. of India, February 25 – 27, 1996.

1996 International Conference on Molecular Association with special section on Applied Biology, Department of Chemistry, Aligarh Muslim University, Aligarh, A comprehensive assessment of potential hazards of chlorinated phenoxy compounds (2,4-D, PCP and 2,4,5-T) in catfish (Heteropneustes fossilis): Chromosomal and Molecular Genotoxicity. May 30 – 31, 1996.

1992 Nat. Symp. Rec. Adv. Integ. Pest Management, Punjab Agri. University, Ludhiana; 2-4 dichlorophenoxy acetic acid (2,4-D) induced larval toxicity and antifertility effects in C. p. fatigans, October 12 – 15, 1992.

1991 Workshop on midterm monitoring of University Grants Commission (UGC) research project, School of Marine Sciences, University of Science and Technology, Cochin, Mosquito Genetics: Genotoxicity of 2,4-D. October 27-29, 1991

1991 Symposium on Pests, Parasites and Environment, Department of Zoology, Aligarh Muslim University, Aligarh; An assessment of mutagenic potential of 2,4 dichlorophenoxy acetic acid as evidenced by micronuclei test in filarial vector C. p. fatigans, March 12, 1991.

1984 III Annual Symposium of Environmental Biologists Association at Kurukshetra University, Kurukshetra, Genetic Studies of six new antennal mutants in Culex pipiens fatigans. December, 21 – 23, 1984.

1980 Seminar on Science, Environment and Ecosystem, Gorakhpur University, Gorakhpur, new mutant Black scales(bs) in Culex pipiens fatigans. February 17 – 19, 1980.

1976 All India seminar on Genetic Studies, Bangalore University, Bangalore, A new mutant (head bristle, hb) in Culex pipiens fatigans. November 18 – 20, 1976.

Scientific and Public keynote lectures

2012 Lecture in National Symposium on emerging trends in biological sciences: with special reference to neurosciences, Interdisciplinary Brain Research Centre, Jawaharlal Nehru Medical College and Hospital, A.M.U, Aligarh. September, 24-25, 2012.

2011 Lectured on Interaction Program on Research Methodology in Biological Sciences at UGC Academic Staff

College, Jan. 4, 2011.

2010 Participated in the Workshop on Translating Sciences and Social Sciences into Urdu; Presented feed back about the outcome of six day workshop; Oct. 25-30 2010, Jointly organized by National Translation Mission, Central Institute of Indian Languages, Mysore and Center for Distance Education, AMU.

2010 Lecture in Annual National Symposium of the Muslim Association for the Advancement of Science- MAASCON-1. Theme: Frontiers in Life Sciences: Basic and Applied; October 23-24, 2010, Dept. of Zoology, AMU, Aligarh.

2010 Delivered a lecture on Human genetic disorders, Academic Staff College, AMU, Jan. 2010.

2009 Delivered a lecture on AIDS awareness in an outreach program, October 2009.

2008 Lecture on Environmental and Molecular Genotoxicity, 2008.

2007 Delivered lectures on ‘Blood and blood mediated diseases and genetic disorders with special reference to HIV

infection and AIDS: A molecular genetic approach’, Academic Staff College, AMU, Aligarh, July 25 2007.

2006 Delivered lecture on Awareness of AIDS, Eritrea Institute of Technology, EIT, Mai Nefhi, September 2006.

2005 Delivered lecture on Blood Transfusion and risk of HIV Infections, Asmara, Eritrea, 2005.

2003 Conducted sessions on 13.1.1995, 27.1.1996, 21.7.1999,2.1.2002(Genetic Disorders), 12.8.2002 (Human Genome), 24.10.2002 (Blood Groups), 1.1.2003, (ABO blood groups), 2.1.2003 (AIDS), Academic Staff College, AMU, Aligarh.

2003 Delivered a lecture on ‘Blood and blood mediated diseases and genetic disorders. Academic Staff College, AMU, Aligarh, August 12 2002 and Jan 2-3 2003.

1999 Delivered lecture on 'Recent advances on AIDS' to university and college participants at Academic Staff

College, AMU, Aligarh, July 21 1999.

1998 Delivered a lecture on 'AIDS: disease its Causes, Cure and Awareness' at Post Graduate College, Hathras ,

January 31, 1998.

1997 Delivered a lecture at All India workshop of Science teachers on 'HIV and Ebola virus organized by The Centre

for Promotion of Science, Aligarh Muslim University, Aligarh, October 24, 1997.

1994 Delivered a lecture on 'AIDS management' on AIDS-day at National Service Scheme (NSS) Centre, Aligarh. Widely reported in National Dailies (Amar Ujala, December 3, 1994; Dainik Jagran, December 3 1994).

Scientific Reviewing Activity

Referee for scientific journals of research organizations: Genomic Medicine Unit, Center of Excellence in Genomic Medicine Research. Member on Panel of International Assessment Review Committee of Genomic Medicine

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Department, GMU and Center of Excellence in Genomic Medicine Research, CEGMR, King Abdulaziz University, Jeddah, since September 2007. Consultant Research Review Panel, Ministry of Education, Asmara, Eritrea. 2002 - 2005. Expert in selection committee of the Indian Council of Agricultural Research Centre, Sheep and wool Research Centre, ICAR. Reviewing research projects and papers of the National Academy of Sciences, The Council of Science and Technology and International Journal of Cellular and Molecular Biology, Slovakia and many more. Research Project Evaluation

Evaluated many projects as ad hoc member on the Panel of National and International Assessment Committees.

Important Titles

Study of PUFA in freshwater fish and their activity on cancer cell lines: Proliferation and Apoptosis, Council of Science and Technology, UP, No. CST/5100, 2014.

Development of Metabolic Prediction System with Nano sensor integrated Genome Grid, Information and communication University, School of Engineering, Daljeon, Korea (Cost US$ 76300 Saudi Riyal 2,938,705, duration 2008 – 2011).

Molecular Genomic Analysis of the causative and associated factors of Non – syndromic hearing loss (NSHL) in a cohort of cases from the Saudi Arabia, King Abdulaziz University, King Fahd Medical Research Center (Cost Saudi Riyal 26,000, duration 1 year).

Hypermethylation of P15, P16 and E-cadherin genes in ovarian cancer, Faculty of Science, Department of Biochemistry, Ain Shams University, Egypt (Cost Saudi Riyal 130,000, duration 1 year).

Human genes to differentiate between Schistosom associated and non - Schistosom - associated bladder cancer and normal bladder, Department of Medical Technology, Faculty of Applied Medical Sciences, King Abdulaziz University, Jeddah, Saudi Arabia (Cost Saudi Riyal 100,000, duration 1 year).

Self assembled polymeric 3-D scaffold for stem growth and differentiation, University of Algarve, Department of IBB/ CBME, Portugal (Cost US$ 35000, duration 2 years).

The epidemic of childhood diabetes in Saudi Arabia; a genomic approach for the role of Helicobacter pylori, Al Salam Hospital, Department of Surgery, Jeddah, Saudi Arabia (Cost Saudi Riyal 97,500, duration1 year).

The dramatic spread of Diabetes mellitus (DM) in Saudi Arabia and a suggested strategy based on Helicobacter pylori strain genotyping, Al Salam Hospital, Department of Surgery, Jeddah, Saudi Arabia (Cost Saudi Riyal 87,200, duration1 year).

Hypertension - a disease of rich people, is flaring among poor population in Saudi Arabia - a genomic medicine study, Al Salam Hospital, Department of Surgery, Jeddah, Saudi Arabia (Cost Saudi Riyal 84,400, duration1 year).

Thrombocytopenic purpura is a rising challenge in Saudi Arabia; a genomic overview for the influence of Helicobacter pylori, Al Salam Hospital, Department of Surgery, Jeddah, Saudi Arabia (Cost Saudi Riyal 91,500, duration1 year).

Are tonsils and adenoids secondary reservoirs for Helicobacter pylori in children of Saudi Arabia; Why it matters? - a genomic clinical view, Al Salam Hospital, Department of Surgery, Jeddah, Saudi Arabia (Cost Saudi Riyal 91,500, duration1 year).

Morphometric systematic and cytogenetic studies of the Drosophilids of Kumaon region, India (CST/AAS, D-3331, dt 16.3.99), Council of Science & Technology, Lucknow.

Prey searching behavior of predatory nematodes. (D – 287/FLS, dt 25.9.99), Faculty of Life Sciences, AMU, Aligarh.

Other Collateral Contribution

2014 Refereed Research paper: ‘Kinetin induces chromosomal abnormalities in African blue lily (Agapanthus praecox sp. Minimus) grown in vitro’.

2014 Reviewer, Ind. J. Exp. Biol. (CSIR, NISCAIR): ‘Fish micronucleus assay to asses genotoxic potential of acid mine

drainage of coal mining’.

2012 Reviewer, Int. J. Human Genetics (IJHG).

2012 Evaluated M. Phil. Synopsis of P. G. Department of Zoology, University of Kashmir, Srinagar.

2011 Reviewer, The Anthropologist, (Ref. No. T – ANTH – 777): To identify the accurate anthropometric and metabolic predictors in assessment of cardiovascular disease risk factors among Punjabi females in India.

2010 Reviewer, Journal of Ecotoxicology & Env. Safety (Elsevier, USA): ‘Evaluation of 2,4-D and Dicamba

genotoxicity in bean seedlings using comet and RAPD assay’.

2010 Edited: Molecular genetics of breast cancer: HER-2/neu gene amplification by fluorescence in situ hybridization

(FISH) and immunohistochemistry(IHC) in Saudi subject; a comparative study., Kelany, A.H.M., Al Qahtani, M.H., and Waseem Ahmad.communicated Specl. J Bioch. and Mol. Biol, 2010.

2009 Edited: Association of specific structural and numerical chromosomal abnormalities in lymphoma cell lines:

the extent of genetic instability. Al Qahtani M. H., Choudhary A.G., Abuzenadah A. M., Gari M. A. and Waseem Ahmad, (communicated Saudi Journal of Med. Res.), 2009.

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2009 Edited Research Paper, Role of tyrosine kinase in the Pathogenesis of Myeloproliferative disorders, King Fahd

Medical Research Center, 2009.

2009 Edited Research paper, Chromosomal abnormalities in Saudi children of Jeddah city, JKAU; Med. Sci. Vol. 15, No. 3, 2009.

2009 Edited Research Paper, Clinical trials on anti - cancer agent PMF - Phase I and Phase II, Medical Biology and

Tissue Culture Unit, King Fahd Medical Research Center, June 2009.

2009 Edited Research Paper, Potential control of nano particles in camel urine on cancer cells, Medical Biology and

Tissue Culture Unit, King Fahd Medical Research Center, June 2009.

2009 Evaluated research paper, Tissue specific expression patterns generated by p1 alleles in Maize, Zea maize, 2009, in the Science J. Umm Al-Qura University, Makkah Al Mukarramah, Makka, Uqujournal_sci@uqu.edu.sa, 16/12/1429 H,.

2008 Edited: Genetic disorders and implication of chromosomal abnormalities: Incidence, pattern and influencing

factors in Saudi children of Jeddah Region. Qahtani A. H., Mandoura N., Choudhary A. G., Abuzenadah A.M., Gari M. A. and Waseem Ahmad, (Communicated Journal of King Abdulaziz University, Medical Sciences) 2008.

2008 Edited Research Paper, Cytogenetic profile of Down’s syndrome in Western Saudi Arabia: A comparative

studies, Sp. J. Bioch. & Mol. Biology, 3(1); 2008.

2008 Progress report prepared on Breast Cancer Research, Center of Excellence in Genomic Medicine Research,

King Fahd Medical Research Center, June 2008.

2008 Edited, Technical and Financial Report of CEGMR for the year 1429 H/ 2008.

2007 Reviewed Project for patenting, Feasibility of Cylindrical Scan Microscope invention, patenting Reem Khojah,

submitted at Center of Excellence in Genomic Medicine Research, Nov. 2007.

2007 Reviewed Research Paper, Sensorineural hearing impairments, Center of Excellence in Genomic Medicine Research, King Fahd Medical Research Center, King Abdulaziz University, Jeddah, 2007.

2007 Reviewed Research project, Karyotypic studies in congenital births, Genomic Medicine Unit, King Fahd

Medical Research Center, King Abdulaziz University, Jeddah, 2007.

2006 Reviewed Research project, Karyotypic studies on lymphoma cell lines, Genomic Medicine Unit, King Fahd

Medical Research Center, King Abdulaziz University, Jeddah, 2006.

2006 Reviewed Research project, Genetic instability: structural and numerical chromosome abnormalities in various lymphoma cell lines, 2006.

2006 Prepared and submitted as principal investigator, Research project for Center for Excellence in Genomic

Medicine Research in Environmental Genomic Research Program, 2006.

2006 Research project on Microarray, Center of Excellence in Genomic Medicine Research, 2006 (co-supervisor).

2005 Substantial contribution, Information guide for first year medical students, Department of Medical Biology,

College of Medicine, King Abdulaziz University, Jeddah, 2005.

2002 Research Paper: The cytogenetic effects of the insecticide malathion on root tips cells of Helianthus annus L.

(Sunflower). Biologia, Cellular and Molecular Biology, Bratislava, Slovakia, 2002.

1998 Research Paper: The effect of …. Fingerlings (No H/2 11.5.98), National Academy of Sciences, India, Allahbad,

1998.

Grant Funding (Major Research Projects)

“Organochlorine and organophosphate mediated genotoxicity and antimutagenicity of natural products in mammalian test system”. Applied for funding to Department of Science and Technology, DST (No. Acad/D-721/MR, dated 25/11/2010).

Cytogenetic and Molecular characterization of chromosome and DNA damage in mammalian test system by some organochlorine and organophorous compounds. University Grants Commission, UGC (No. Acad/D-641/MR, dated 29/10/2010)

Genotoxic studies on Dichlorophen and Dichlorovos in mammalian test system using multiple genetic assays. Council of Science and Technology, UP (No. Acad/D-468/MR, dated 09/09/2010).

Projects Executed .

2004-05 Eritrea Institute of Technology, Department of Biology, Asmara, sponsored project on ‘Biochemical and cytological studies on possible DNA reactants and evaluation of some antimutagenic effects of some endogenous plant products’(December 2004).

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1998-2002 Indian Council of Agriculture Research (ICAR) sponsored project on 'In-vitro genotoxicity of some phenoxy

compounds using multiple genetic assay system on some selected cultured cells of common catfishes (Heteropneustes fossilis and Clarias batrachus). (F.No. 4(36)/95 ASR I) Duration: 3 years, January 1998 to July 2002.

1992-95 Indian Council of Agricultural Research (ICAR) sponsored project on 'Genetoxic studies on the Catfish, Heteropneustes fossilis' (F. No 4(16)/91 - ASR (1). Duration: 3 years, July 1992 to June 1995; funds: Rs. 40 lakh.

1990-93 University Grants Commission (UGC) sponsored project on 'Mosquito Genetics' (No. F 3-206/90, SR II). Duration : 3 years, May 1990 to April 1993; funds: Rs. 75,000/-

Projects Under Review (abroad, unimplemented)

2008 Chemical induced genotoxic estimates and antimutagenic assessment by natural extracts, under consideration by the General Directorate of Research Grants, King Abdulaziz City for Science and Technology, KACST, MOH, Riyadh, Feb 2008 Ref. No.: ARP-28-146, budget 1.5 million Saudi Riyal, (duration three years).

2007 Environmental Genomic Research Project, under CEGMR, KFMRC, KAU, considered by King Abdulaziz City of Science and Technology, KACST, MOH, Riyadh, June, 2007 (duration three years).

(These projects could not be implemented despite being reviewed favorably as the time for deputation not be extended by Aligarh Muslim University, AMU, then).

Research Profile

Research Specialization (major scientific field of interest)

Molecular Genotoxicity and Antimutagenicity (Toxicogenomics) Genomic Medicine Genetics and Control of Insects Vector of Disease (Mosquito Genetics)

Resumé of Research Work

Environmental and Molecular Genotoxicity

Our group is engaged in active research on in-vivo and in-vitro genotoxicity of aquatic organisms. Studies conducted on chlorophenolic coumpounds indisriminately used as weedicides have shown positive results in many organisms as in freshwater fishes (Ecotoxicology and Environmental Safety,54, 25-29, 2003; Mutation Research, 518, 135-144, 2002; Chromosoma, 110, 570-574, 2002; Mutation Research, 518, 135-144, 2002; Ecotoxicology Environmental Safety, 54, 25-29, 2002; filarial vector (Bull. Société Ent. Suissé, 56, 271-273, 1983; Bull. Société Ent. Suissé, 67, 169-175, 1994; Japan J. Sanit. Zool. 35, 149-150, 1984; Experientia, 41, 1465- 1467, 1985; Poll. Res. 13(4), 345-349, 1994; J. Env. Biol., 17(4), 331-337, 1996) and in Allium (Mutation Research, 514, 105-113, 2002; Sci. Dilliman, 2012). Histopathological studies on germinal epithelium, clastogenic effects on various cell types and biochemical lesions of DNA have invariably shown remarkable results in catfishes (Chem. Env. Res., 5, 267-281, 1996; Ind. J. Exp. Biol. 36, 304-307, 1998). The practical value of micronucleus assay aided by Computer Image Analysis (CIA) have shown better computing statistics and more objective assessment of micronuclie (Chromosoma, 110, 570-574, 2002). Studies have further focussed on electrophoretic reactivity as the fundamental cause of toxicity and stress of some xenobiotics on aquatic organisms (Chemosphere, 55, 257-265, 2004). Cytochemical estimation of protein and DNA revealed a significant variation of bands (Chem. Environ. Res., 5, 267-281, 1996). Pentachlorophenol - mediated cellular and changes in germinal epithelium and kidney cells of H. fossilis have shown ample evidence of apoptosis (Proceedings of Environ. Mutagen Society, Lucknow, 19-21 March, 2002, Proceedings of Environ. Mutagen Soc., 2010, J. Life Sciences, USA, accepted, 2011). Research is further extended to herbicides for apoptotic and mutagenic evaluation (Saudi J. Biol. Sci., 2012). Techniques such as comet assay, DNA diffusion method, MNT (CIA) are being incorporated. Inhibitory activity of some endogenous substances (neem and vitamins) viz-a-viz chemicals used, is in progress for the assessment of antimutagenicity (STOTEN, Science of Total Environment, Elsevier, 2005). Detection of DNA damage by alkaline single cell gell electrophrosis is the sensitive parameter used successfully against some chemicals (Ecotoxicology and Environmental Safety, Elsevier, 2005).The work is further extended in other test system, Rattus norvegicus and Mus musculas (Ecotoxicology and Environmental Safety, Elsevier, 2006, Saudi J. Biol. Sci., 2012 ) and research work is earnestly persued along these lines since 2010-14.

Other aspects like oxidative damage and cytoarchitural assesments (Environt. Toxicol., 2014), In silico studies (Biotech & Appl. Biochem.m 2014) have been investigated. Genotoxic studies expanded further with newer parameters and organisms with protective measures (Int. Sch. Res., 2014; Int. J. Cytol., 2013; Toxicol., 2013; Sci. Dilliman, 2012; Eco. & Env. Safety, 2006). More recently commet assay, mitochondrial membrane potential and other DNA studies have been further incorporated (2014). Genomic Medicine

Active researches in CEGMR earnestly started on Cancer Genomic, Stem cell, Neurogenetics and PGD. Many international researches were also admitted in the Center. As a result number of research employing molecular parameters have started yielding results. The cytogenetic profiles of Down’s syndrome by G banding presented a very detailed insight of comparative studies (Sp J Biochem Mol Biol, vol3, no1, 2008, J. Med. Sciences, US, China, 2010. Similarly genetic disorders and implication of chromosomal abnormalities have been analysed very elaborately giving incidence, pattern and influencing factors (JKAU: Med. Sci., vol 15, no 3, 2008; Proc. Env. Mut. Soc., 2010). All these studies are unique in relation to Saudi Arabia. FLT3 oncogene mutations in acute myeloid leukaemia has been analysed

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successfully with the help of conformation sensitive gel electrophoresis (Int. J. Mol. Sci., 2008). Frequency of genetic disorder, G6PD Mediterranean mutations among a group of Saudi patients have given new insight about its pattern in Jeddah region (Int. J. Lab. Hem.,2008). Recently a study on Molecular Genetics of breast cancer using HER_2/neu gene amplification by FISH and IHC has been concluded( joint study with Faculty of Medicine, KAU, Jeddah, CEGMR, KFMRC, 2010). In addition, analysis on serum protein and enzyme levels in human subjects with osteoarthiritis have given interesting results (Med. Biochem., 30:15-24, 2011). In silico and in vivo studies show significance response in human brain tissue for certain enzymes (Biotech & Appl. Biochem., 2014)

Research Background

Exposed to the state of the art laboratories of Molecular cytogenetic techniques such as comparative genomic hybridization (CGH), microarray, immunehistochemistry (IHC) and PCR at Genomic Medicine Unit, GMU, Center of Excellence in Genomic Medicine Research, CEGMR, King Fahd Medical Research Center, KFMRC, King Abdulaziz University, Jeddah, Saudi Arabia. At the Centre For Advanced Studies on Animal Genetics and Breeding, NDRI (ICAR), KARNAL, different methods of Animal cell and tissue culture technology were learned including in vitro culture of mammalian embryos, culture of bovine gametes and neonatal rat skin of fibroblasts and maintenance and preservation of cell lines. Special attention was paid for training in DNA fingerprinting and isolation and characterization of DNA at the Biotechnology Division of the National Bureau of Animal Genetic Resources, Karnal, Haryana. Also initially obtained practical training on various aspects of genetics and cytogenetics at the Department of Zoology (AMU), Aligarh. The training and international exposure of various laboratories has made the author well versed with latest Biological, Medical and Molecular Cytogenetic techniques in the field of Genomic Medicine and Molecular Genotoxicity.

Post-doctoral Research/Training Experience

Institution attended during exposure are: Centre of Excellence in Genomic Medicine Research, CEGMR, Environmental Genomics Research Program, EGRP, Genomic Medicine Unit, GMU, King Fahd Medical Research Centre, King Abdulaziz University, Jeddah; National Dairy Research Institute (NDRI, Indian Council of Agricultural Research), Haryana; National Bureau of Animal Genetic Resources, NBAGR, Karnal; Academic Staff College, AMU, Aligarh; School of Marine Sciences, University of Science and Technology, Cochin; Dept of Biotech, New Delhi and Department of Biotechnology, AMU, Aligarh. Details:

2006-09 Genomic Medicine Unit (GMU R&D), Centre of Excellence in Genomic Med & Environmental Genomic

Research Program, King Fahad Medical Research Centre (KFMRC), King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia.

Nature of work: Genetic and Molecular Cytogenetic tech., Lymphoma cell lines; Microarray, q PCR, DNA sequencing, Molecular cytogenetic techniques.

2000 Centre for Advanced Studies in Animal Genetics and Breeding, National Dairy Research Institute, NDRI , and

Nat. Bureau of Animal Genetic Researches, NBAGR, (Indian Council of Agricultural Research, (ICAR), Karnal, Haryana.

Nature of work: Cellular and Molecular Techniques.

1996 Department of Biotechnology, Aligarh Muslim University, Aligarh.

Nature of work: Use of personal computers in Bioinformatics

1993 National Dairy Research Institute, Indian Council of Agricultural Research, Karnal, Haryana. Nature of work: Animal Tissue and Cell culture Technology.

1991 Cochin University of Science and Technology, School of Marine Sciences, Cochin.

Nature of work: Mosquito genetics project.

1990 Academic Staff College, Aligarh Muslim University, Aligarh.

Nature of work: Orientation skills.

1988 Academic Staff College, Aligarh Muslim University, Aligarh. Nature of work: Orientation training

1983 Division of Genetics, Department of Zoology, Aligarh Muslim University, Aligarh.

Nature of work: Genetics, Techniques of Cytogenetics and Biological control of mosquitoes.

Visits to Labs Engaged in Mosquito Research

(During Doctoral Program) Visited Bangalore University, Department of Zoology where pioneer work on cytogenetics was in progress under the leadership of Prof. B. N. Chowdaiah in Culex pipiens fatigans. Interacted with the pioneer scientists like Subbarao S. K., Adak T., Krishnamurthy B. S. in Malaria Research Center (VCRC) – a joint venture of WHO and ICMR. The team produced outstanding work on cytoplasmic incompatibility. Also visited Punjab University, Chandigarh where Sudershan C. and his team was engaged in Cytogenetics and somatic cell chromosome studies on mosquitoes. Our own lab under the stewardship of late Prof. Adhami U. M., who obtained his doctorate from Notre Dame University, USA had done extensive work on yellow larva in Aedes aegypti. We were exposed to high quality research work (under the aegis of WHO Research Project), were engaged in Insecticide resistance and induced mutations in Aedes aegypti and Culex fatigans. There was an active coordination between our lab and other lab of reputes in America (Kitzmiller, J. G. Department of Zoology, University of Illinois, Craig G. B., Rai K. S., Adhami U. M., Department of Biology, University of Notre Dame), Britain (Mason G. F., Ross Inst. Sch. of Hygiene & Trop. Med., McDonald, Department of Ento. Liverpool), Canada (Brown A. W. A., Department of Zoology, University of West Ontario), Italy (Frizzi, Inst. of Genetics) and Japan (Takeo Tadano, Department of Med. Zoology, St. Mariana University).

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There was a brief association and thought of collaboration of controlling the dengue fever mosquitoes with Prof. Khalid Al Ghamdi, WHO Project Director and Prof. of Biology at KAU, Jeddah. Although offered as Advisor to WHO project, but could not collaborate as my extra ordinary leaves ended and I was to join my parental university. The exposures in various laboratories produced rich experience in research, though.

Research Supervision

Experience: 38 years (since 1976) Research Degrees Awarded: Ph.D. / M.Phil., 12 In progress Ph.D: 2, M.Phil: 2 and Ph.D. Co-guidance: 1

Topics of Ph. D. and M. Phil. In Progress:

DNA damage and biochemical alteration in mammalian tissues exposed to Organophosphate compounds: Possible Amelioration by Phytoextract.

Genotoxic studies of some organochlorine compounds in a mammalian model: Modulation by Crocus sativus extract.

Genotoxic potential of non steroidal anti-inflammatory drugs stressed in mammalian model

Assessment of potential cytogenotoxicity of non steroidal anti-inflammatory drugs (NSAIDS) in mammalian model

Important Titles of Ph.D. Thesis as Research Guide / External Examiner

2014 Genetic Epidemiology of Type 2 Diabetes and its relationship with obesity and cardiovascular disease (Guru

Nanak Dev University, Amritsar, Punjab; Viva Voce 6.3.2011)

2014 Biology and Control of insect pests of cotton (Bollyworms). (Dr, Bhimrao Ambedkar University, Agra, U.P.)

2009 Epidemologic, cytogenetic and control of Dengue fever vector, Ades aegypti, Ph.D. Thesis, Department of

Arid zone Entomology, King Abdulaziz University, Jeddah, (Saudi Arabia, in progress): Molecular identification of dengue fever vector A. aegypti in Jeddah , KSA (Partial fulfillment, Al Azab, Res. Scholar).

2008 The Molecular diagnosis of Duchenne Musculare Dystrophy, MS Disseratation (A. H. E.), Department of

Biochemistry, Faculty of Science, King Abdulaziz University, Jeddah (Saudi Arabia).

2007 The evaluation of HER-2 amplication by florescence in situ hybridization (FISH) in Saudi females with breast

cancer, MS project, King Abdulaziz University, Jeddah (Saudi Arabia).

2004 Genotoxic studies on phenoxyaceticacid derivatives and evaluation of antimutagenic effect of neem extract in Channa punctatus, Ph.D Thesis, Aligarh muslim University, Aligarh (India).

2003 Mutagenic risk due to some weedicides on a freshwater fish Clarias batarachus, Ph.D Thesis, Aligarh Muslim

University, Aligarh (India).

2002 Herbs and Behavior, Camel Behavior, and Lizard Behavior, Research presentation for evaluation of Full

Professorship, King Abdulaziz University, Jeddah (Saudi Arabia, Ref. No. 3451 T. A., MOHE, Dept. of Sci. Council Affairs).

2002 Pollutant-induced modulation of enzymatic antioxidant in Indian freshwater fish, Ph.D Thesis, Jamia

Hamdard (Hamdard University), New Delhi (India).

2002 Studies on the evaluation of antimutagenic potential of herbs against some dietary and environmental

mutagens, Ph.D Thesis, Jamia Hamdard University (Hamdard University), New Delhi (India).

1994 Genotoxic studies on Pentachlorophenol (PCP) in catfish, Heteropneustes fossilis, Ph.D. Thesis, Aligarh Muslim University, Aligarh (India).

1993 Cytogenetic effects of 2,4-D in Teleost fish Heterpneustes fossilis, Ph.D. Thesis, Aligarh Muslim University,

Aligarh (India).

1991 Genetic, cytogenetic and developmental effects of 2,4-D on mosquitoes Culex pipens fatigans, Ph.D. Thesis,

Aligarh Muslim University, Aligarh (India).

1991 A genetico-environmental study of Muslims of Goalpara district (Assam), Ph.D. Thesis, Aligarh Muslim

University, Aligarh (India).

Society Memberships

Environment Mutagen Society of India. (An affiliate of International Association of Environmental Mutagen Societies, Memb. No. LM315)

All India Congress of Cytology and Genetics.

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Books

Published

2013 Genetics and Genomics; Published by Pearson Education Incorporation, Dorling Kindersley, India. (ISBN NO. 978-81-317-71099, Chapters 20, Pages 565, First Impression, Full Color, Over 400 figures, Price Rs. 600/-)

2009 DNA fingerprinting (Suragh Rasan DNA), Published by Centre for Promotion of Science, Aligarh Muslim University, Aligarh, India 2002. (Wide circulations. Many editions between 2002 - 2014)

2008 Human Medical Biology Lab Manual for Medical and Allied Medical Science students. (242 P; 17×24 cm;

ISBN 978-9960-58-998-5; First Edition), Published by Dar Khawarizm Academic Publishing Co., Saudi Arabia.

2007 Chief Editor, CEGMR official ‘GENOMEXCEL’ magazine, at KFMRC, King Abdulaziz University, Kingdom of

Saudi Arabia.

2005 Genetics and Cytogenetics for degree students, published by Eritrea Institute of Technology, Ministry of Education, Asmara, Eritrea. (Wide circulation in various Universities and Colleges of Eritrea).

2005 ‘Facts about HIV Infection and AIDS: Problems and Approaches’ Published by Arun Publication,( Price 575) II

edition.

2005 Freshman Biology, Published by Eritrea Institute of Technology, Ministry of Education, Asmara, Eritrea,

2005. (Wide circulation)

2004 'AIDS: Problems and Approaches', Published by Sai Publication, New Delhi,(ISBN 81-87798-19-X,120PP, Price

US$ 16).

Books Reviewed

2009 Basic Genetics: Text book and Activities, Total Chapter 7, Pages 219. Author: Ahmed Abouelmagd; Department of Medical Biology, Jazan University, Saudi Arabia.

2008 Medical Aspects of Human Genetics. Author: Mohsen A El – Hazmi, Department of Medical Biochemistry & WHO Collaborating Center for Blood Genetic Disorders, College of Medicine, King Khalid University Hospital and Department of Biochemistry, College of Science, King Saud University, Riyadh, Saudi Arabia.

Newsletter

Editing, Newsletter ‘Genomexcell’ (quarterly), Center of Excellence in Genomic Medicine Research, King Fahd Medical Research Center, King Abdulaziz University, Jeddah, Saudi Arabia, http://www.kau.edu.sa/centers/cegmr.

Editing, Newsletter ‘Horizon’ (fortnightly), EIT Mai Nefhi, Asmara.

Editing, Newsletter ‘Newzoology’, Department of Zoology, Aligarh Muslim University, Aligarh, India.

Member of Organizing Committees of Scientific Events

2013 Advisor, National conference on insect diversity and systematics and molecular approaches, 28-30 October,

2013.

2013 Member organizing committee, International symposium on ‘Control of Helminth parasite and RNAi

workshop, 11-12 February, 2013.

2012 Member organizing committee, National symposium on emerging trends in Biological Sciences, 24-25 September 2012.

2010 Member organizing committee, Symposium on frontiers in life sciences; Basic and Applied, 23-24 October,

2010.

2008 Member organizing committee, First Annual Genomic Day Conference, Center of Excellence in Genomic

Medicine Research, CEGMR, King Fahd Medical Research Center, KFMRC, King Abdulaziz University, Jeddah, Saudi Arabia, November, 2008.

2007 Core member of team, created and organized Center of Excellence in Genomic Medicine Research, CEGMR.

Established Researches on major lines including Cancer, Stem cells, Neurogenetics and PGD. Recruited technical and research personals of CEGMR. Performed analysis, results, conclusions; written manuscripts, prepared research projects and technical reports.

2007 Member Editorial Board, ‘Genomexcell’ the official Newsletter. The responsibilities: Planning the issue and contents, creating progress reports of the Center, visualization of cover and illustrations, writing current scientific innovation relevant to researches at CEGMR, reporting scientific events and visits of international visitors. Evaluation and editing of research papers and books. Participating in the scientific affairs and documenting brochures, seminar lectures and presentations.

2007 Member Advisory Committee; Center of Excellence in Genomic Medicine Research, CEGMR, representing

global body. Responsibilities: to implement organizational rules and regulations.

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2007 Member organizing committee for preparation and establishing the center of excellence in various research

programs (cancer screening research , genetic diseases screening research, stem cell research, and environmental genomic research: CEGMR, EGMR: an international and national joint venture , King Fahd Medical Research Center, King Abdulaziz University, Jeddah, Saudi Arabia.

2002 Coordinator LXXIV Academic Staff Orientation Program, University Grant Commission, (AMU), Aligarh.

2003 Resource person, Academic Staff College, Aligarh Muslim University, Aligarh.

1996 Member Organizing Committee, International Symposium on Molecular Association with special section on

Applied Biology, Dept. of Chemistry, Aligarh Muslim University, Aligarh.

1993 Member Organizing Committee, National Symposium on Pests, Parasites and Environment, Department of Zoology, Aligarh Muslim University, Aligarh.

Interactions with Foreign Visitors

Had an active interaction with the international research dignitaries visited CEGMR between 2006 to 2009. Some of them are: Dr. Don Smith (General manager, Business Development, Royal Society of New Zealand), Prof. Ricahrd Ivell (Head, School of Molecular and Biomedical Science, University of Adelaide, Australia), Prof. Daniel Peterson (Executive Director, Center of Stem Cell & Regenerative Medicine, Rosland Franklin University, USA), Prof. Leung Yi (Consultant pathologist, Research Connect P. Ltd. Australia), Dr. Abdul Majid (Department of Biological Chemtsry, John Hopkins University, USA), Prof. Muhammad Dahmani Fatallah and Prof. Wael Kafienah (Department of Cellular and Molecular Medicine, University of Bristol), Prof. Ghulam Mufti (Microarray,United Kingdom), Prof. John K. Davis (Stem cell Res.Canada), and many more.

Teaching Profile

Teaching Experience and Position held Experience 30 years International exposure five years

Permanent affiliation as Prof of Zoology and as Head, Div of Genetics, Dept of Zoology, Aligarh Muslim University, Aligarh, India: international assignments as Prof of Biology, Eritrea Institute of Science and Technology, Asmara (UNDP); Prof of Medical Biology, Prof of Biological Science and honorary member research board, Genomic Medicine, King Abdulaziz University, Jeddah. Details:

Oct 2008 - Sept 2009 Professor of Biological Science, Department of Biological Science, Faculty of Science,

King Abdulaziz University, Jeddah, KSA

Sept 2006 - Oct 2008 Professor of Medical Biology, Department of Medical Biology, Faculty of Medicine,

King Abdulaziz University, Jeddah, KSA

Oct 2003 - Sept 2005 Professor of Biology, Department of Biology, Faculty of Science, Eritrea Institute of

Technology, Mai Nefhi Asmara, (UNDP)

Nov 2005 - contd. Professor of Genetics/Zoology, Division of Genetics, Department of Zoology, Faculty of Life Science, Aligarh Muslim University, Aligarh, India

Jan 1998 - Mar 2002 Senior Associate Professor/ Senior Reader, Division of Genetics, Department of

Zoology, Faculty of Life Science, Aligarh Muslim University, Aligarh, India

Mar 1994 - Jan 1998 Associate Professor/ Reader, Division of Genetics, Department of Zoology, Faculty of

Life Science, Aligarh Muslim University, Aligarh, India

Mar 1992 - Mar 1994 Senior Assistant Professor/ Senior Lecturer, Division of Genetics, Department of

Zoology, Faculty of Life Science, Aligarh Muslim University, Aligarh, India

Jan 1985 - Mar 1992 Assistant Professor/ Lecturer, Division of Genetics, Department of Zoology, Faculty of Life Science, Aligarh Muslim University, Aligarh, India

International Assignments

2008-09 As Professor of Biological Science in the Faculty of Life Science, King Abdulaziz University, Jeddah

2007-09 As Senior Editor, official Newsletter “Genomexcell” of Centre of Excellence in Genomic Medicine Research,

King Fahd Medical Research Centre, King Abdulaziz University, Jeddah.

2006-09 As Member of research team and Consultant research at Genomic Medicine Unit and the Centre of Excellence in Genomic Medicine Research, Environmental Genetic Research Program at King Fahd Medical Research Center, King Abdulaziz University Jeddah, since September 2006.

2006-08 As Professor of Medical Biology in the Department of Medical Biology, College of Medicine, King Abdulaziz

University, Jeddah, Kingdom of Saudi Arabia, since September 2006 to October 2008

2003-05 As Professor and Head, Department of Biology, Eritrea Institute of Technology (EIT), Asmara, Eritrea. (UNDP/World Bank funded project), from October 2003 to September 2005.

CV Prof. Waseem Ahmad

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Postgraduate, Graduate and Medical Teaching Instruction in Aligarh Muslim University, India

­ Post graduate courses: M Sc Prev and Final: (Genetics specialization) Transmission Genetics, Human Genetics, Genetics and Molecular Biology, Advanced Genetics and Gene Manipulation,

Environmental and Molecular Genotoxicity ­ Graduate and under graduate courses: B Sc ( Hons ) Cell Biology , Cytology and Cytogenetics, Genetics and Molecular Biology, Animal Biology ­ Pre-Medical Courses: General Biology, Human Genetics, Molecular Biology Instruction in King Abdulaziz University, Saudi Arabia

­ Medicine/ Pharmacy/ Med Tech/ Dentistry Courses: Medical Biology, Genetics and Molecular Biology ­ Life Science Courses: Introductory course in Biology (BIO-110) Advance Molecular Cytogenetics, BIO 335 (Course for Ph.D.)

Instruction in Eritrea Institute of Technology, Asmara

­ Freshman, Degree, Health Science Courses: General Biology, Genetics and Molecular Biology, Cell Biology

Curricula Development and Further Education

Wide experience of curricula development of Genetics and Molecular Biology, Zoology, Medical Biology and Allied Medical Sciences in various capacities: as member, board of studies and as In-charge Division of Genetics, Department of Zoology, Faculty of Life Sciences, Aligarh Muslim University, Aligarh. Courses developed for Doctorate/ M Phil. Courses designed for M Sc, B Sc, and Pre Medical levels; and as member executive council, EIT and Head, Department of Biology, Eritrea Institute of Technology, Asmara; and as Member board of studies, Dept of Genetics and Medical Biology, College of Medicine, King Abdulaziz University, Jeddah, Department of Biological Science, Faculty of Life Science, King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia. Important courses developed:

Post Graduate Transmission Genetics, Human Genetics, Genetic Tools and Techniques, Advanced Genetics and Gene manipulation (Recombinant DNA technology), Environmental and Molecular Genotoxicity. Graduate and Under Graduate Cell Biology, Genetics, Evolution and Applied Zoology, Genetics and Molecular Biology, Animal Biology, Physiology, Advanced Placement Course in Biology (Biology I and Biology II). Medical and Allied medical Science Medical Biology, Genetics, Physiology, General Biology, Medical Genetics and Cytogenetics. Ph. D. / M. Phil. Techniques, Methodology, Research Ethics, Manuscript Writing etc.

Miscellaneous / Administrative Activities Acting Chairman and Head, Department of Zoology (AMU), as and when required since 2011; works include

Administering Department, Research and Teaching, Admissions and Examinations.

Member Selection Committees as Vice – Chancellor nominee

Member Moderation Committee for moderation of UG, PG, M. Phil., Ph. D. examination papers

Member Committee for verification / certification of API scores for Assistant / Associate / and full Professors of Life Sciences Faculty

Member Standing Committee for attendance, Faculty of Life Sciences

Member Professional examination board (Bhopal, MP)

Expert Assessment Committee, Central Institute of Sheep and Wool Research, Jaipur, Rajasthan

CV Prof. Waseem Ahmad

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Observer University AMU Students Body elections.

Member, Board of Studies, Department of Biological Science, Faculty of Science, King Abdulaziz University, Jeddah, 2009

Member, Board of Studies, Department of Medical Biology, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia, 2006 – 2009

Member, Board of Studies and Member, Executive Counsel, Eritrea Institute of Science and Technology, EIT, Asmara, 2002 – 2004

Head and In-charge of the Division of Genetics, Department of Zoology, Aligarh Muslim University

Member on the Faculty of Life Sciences and Programme Officer of National Service Scheme (NSS)

Resource person and Consultant, Coaching and Guidance for Medical Entrance Test at various centers of the University.

End