curriculum vitae - massey universitymckruger/kruger_marlena_cv_dec_20… · curriculum vitae...

CURRICULUM VITAE

Marlena C. Kruger

19 Ron Place

Palmerston North 4410

06 350-5905

[email protected]

Marlena Kruger Curriculum Vitae

2

Career Summary

2000 – Present

January 2008 -

October 2005 -

present

Jul/Aug 2005

Jul 2005 – Present

2002 – Oct 2005

2000 – Present

2000 – 2002

Massey University

New Zealand

Institute of Food

Nutrition and Human Health

Director of Research, IFNHH

Professor of Nutritional

Physiology

Acting Head of Institute

• Director: Human Nutrition

and Health Cluster

• Associate Professor in

Nutrition

• Research Leader Human

Nutrition Cluster

• Senior Research Scientist

1991 – 2000

1996 – 2000

1991 – 1995

University of Pretoria

South Africa

• Associate Professor in

Physiology

• Senior Lecturer in Physiology

1998 – 1990 University of Texas

Austin, USA • Post-doctoral Fellow in

Biochemistry

1986 – 1987

1987

Medical University of

South Africa

Max Plank Institute for

Medical Research

Heidelberg, Germany

• Senior Lecturer in Physiology

• Research Exchange

1979 – 1984 Medical University of

South Africa

South Africa

• Lecturer in Physiology

1975 – 1979 Potchefstroom

University for Christian

Higher Education

South Africa

• Teaching Assistant in

Physiology (part time)


3

Overview of Career Roles and Responsibilities

2000 – Present

Institute of Food, Nutrition and Human Health

Massey University, New Zealand

Oct 2005 – present Professor of Nutritional Physiology

Jul/Aug 2005 · Acting Head of Institute

July 2005 – Present · Director: Human Nutrition and Physiology

2002 – Oct 2005 · Associate Professor in Nutrition

2000 - 2002 · Research Leader Human Nutrition Cluster

2000 – 2002 · Senior Research Scientist

Responsibilities:

2005- 2009

Co- Director and Professor: Human Nutrition and Physiology Division

• Management of 30 teaching and research staff

• Research Leadership for the Division

• Funding management

• Staff management

2004 - present

Research IFNHH:

Director of Research for Institute of Food, Nutrition and Human Health

• Performance based Research Funding strategy management

• Coordination of research between Divisions

• Quality control of funding applications

• Strategic planning for IFNHH around future research opportunities

2000 – Present

Research Leader Human Nutrition Division

• Leading Scientist of bone and joint health, running of human nutritional trials

• Investigating in rodents, novel ingredients of milk, PUFAs as well as other

ingredients to improve calcium bioavailability

• Investigation of bone cell growth/ osteoclastogenesis promoting activity of bioactives

using in vitro techniques

• Human nutrition trials with biochemical markers of bone turnover/ antioxidant status

as primary outcomes

• Scientific advisor for Industry including Fonterra Brands, New Zealand King Salmon.

(For further details on research and research training refer to Appendix I))


4

Overview of Career Roles and Responsibilities ctd

2000 – Present

Institute of Food, Nutrition and Human Health


Teaching

• Supervision of post-graduate students in Nutritional Science

• Course Coordinator – Nutrition for Sports and Performance BSc III

• Course Coordinator – Advanced Sports Nutrition

• Selected topics in BSc III Human Nutrition

• Selected topics for Master’s in Nutritional Science (MSc, PhD)

(For further details on teaching experience and topics of graduate student studies refer to

Appendix II)

1991 – 2000


South Africa

1996 – 2000 · Associate Professor in Physiology

1991 - 1995 · Senior Lecturer in Physiology

Responsibilities:

Research

• Independent researcher leading 12 technical and academic team members

• Supervision of graduate students (BSc Honours, MSc and PhD)

• Annual Research report of the department

• Distribution of funding in Department

• Contract Research for Scotia Pharmaceuticals/ Rhone Poulenc Rhorer

Teaching

• Course coordinator: BSc III Exercise Physiology; BSc Honours Human Physiology,

MMed Sports Science,

• Research Methodology (all graduate students of the Faculty of Medicine)

• Human Physiology for undergraduate and graduate students

• Supervising graduate students

1988 – 1990

University of Texas · Post-doctoral Fellow in Biochemistry

Austin, USA

Responsibilities:

• Investigation into novel skeletal muscle proteins, nebulin and titin, comprising of

protein purification, antibody generation and localisation of proteins in muscle

myofibrils


5

Overview of Career Roles and Responsibilities ctd

1985 – 1987

Medical University of South Africa · Senior Lecturer in Physiology

1987

Max Planck Institute for Medical Research

Heidelberg, West Germany · Research Exchange

Responsibilities:

• Undergraduate and graduate teaching in Human Physiology;

• Research: Purification of the skeletal muscle ATPase and characterisation;

undertaking PhD studies

1979 – 1984

Medical University of South Africa · Lecturer in Physiology

Responsibilities:

• Undergraduate teaching of Human Physiology; undertaking PhD studies

1975 – 1979

Potchefstroom University for Christian Higher Education

South Africa · Teaching Assistant in Physiology

(Part-time)

Responsibilities:

• Technical assistant for physiology undergraduate practical work/ undertaking MSc

studies (full-time)


6

Achievements/ Appointments

2011 • Subject area facilitator; PBRF panel Health for College of Sciences,

Massey University

2010 • Expert Panel Member: European Commission FP7 funding round;

KBBE 2010; Topic: Evaluation: Diet and prevention of functional

decline of the elderly

2008 -

current

• Panel member: Massey University Research Development Fund

2008 -

current

• Member: College of Sciences Promotions Committee

2006 -

current

• Professor: Massey University Promotion Procedural review committee

2006 • PBRF rating “A” Health panel

2005 • Professor of Nutritional Physiology (Personal Chair)

• IFNHH

• Massey University, New Zealand

2005 • Director: Human Nutrition and Health Cluster

IFNHH


Jul – Aug

2005

• Acting Head of Institute

IFNHH


2005 • Reappointed: Panel Member, Performance Based Research Funding,

Health Panel

Ministry of Education, New Zealand

2005 • Performance Based Research Funding, Consultation Committee


2004 • Director of Research

IFNHH


2004 -

current

• Associate Editor: Journal of the Science of Food and Agriculture

2004 · PBRF rating: B

2004 • Reviewer/Consultant; Performance Based Research Funding, Health

Panel


2003 –

Current

• Member Executive Committee Institute of Food Nutrition and Human

Health Massey University, Palmerston North

2000 –

Current

• Editorial Board: Prostaglandins, Leukotrienes and Essential Fatty Acids


7

2003 –

2004

· Panel Member, Performance Based Research Funding, Health Panel


Awards

2009 • Runner-up: Best publication; Group; School of Health Sciences,

University of Pretoria, South Africa

2000 • Best Publication in Endocrinology, South African Society for

Endocrinology, Metabolism and Diabetes

• Best Publication (runner-up), Faculty of Medicine, University of

Pretoria

1999 • Hendrik Verwoerd Research Trust Award for Excellence in Research

1999

• Best Publication Overall (runner-up), Faculty of Medicine,


1994 • Best oral presentation in Endocrinology; Society for Endocrinology,

Metabolism and Diabetes of South Africa, travel grant to 12th

International Conference on Calcium Regulating Hormones

Melbourne, Australia

1988-1990 • Postgraduate Fellowship; Foundation for Research Development

South Africa

1987 • German Academic Exchange Service (DAAD) Scientific Exchange

Grant Max-Planck Institute for Medical Research

Heidelberg, Germany

1977–1979 • Centre for Scientific and Industrial Research Training Grant


8

Education and Qualifications

• Post-doctorate (Biochemistry) University of Texas

Austin, USA

1988 – 1990

• Post-doctorate (Physiology) Max-Planck Institute for Medical

Research

Heidelberg, Germany

1987

• PhD (Physiology) Medical University of Southern

Africa

South Africa

1986

• Master of Science (Physiology)

(cum laude)

Potchefstroom University for

Christian Higher Education

South Africa

1979

• BSc Honours (Physiology)

(cum laude)

Potchefstroom University for


South Africa

1977

• BSc (Physiology/Biochemistry) Potchefstroom University for


South Africa

1976

Training Courses Attended:

Management:

• Management for the New

Manager

• People Management in Project

Management

Brightstar

Wellington

Project Plus

Wellington

2008

(2 days)

2005

(2 days)

• Team Leader Training

Workshop

Sterling Personnel

Palmerston North

2003

(2 days)

• Introduction to Management Massey University


(21 hours)

Research:

• Human Ethics III

Cross Cultural Research

Massey University


• Data Management in Clinical NHMRC 2003


9

Trials University of Sydney

Sydney, Australia

• Obtaining a Marsden Grant Massey University

New Zealand 2002

• PhD Supervision Massey University

Palmerston North

2002

• Human Ethics II Massey University

Palmerston North

2002

• Performance Development

Reviews (Interviewer)

Massey University

Palmerston North

2002

• Clinical Trials of Functional

Foods and Nutraceuticals

Auckland University

Auckland

2001

• Team Research Massey University

Palmerston North

2001

• Research and Development

Project Management

New Zealand Dairy Board 2000

• Project Management Carson Group

Wellington

2000

• Presentation Skills Communicate Consultants Limited

2000

• Plain Language Writing

• Effective Business Documents

Write Consultancy

Wellington

2000

• Undertaking Research with

Human Participants

Massey University

Palmerston North

2000

Teaching:

• Problem-Based Learning Massey University

Palmerston North

2001

• Supervision of Graduate

Students

Massey University


• Performance Development

Reviews

Massey University

Palmerston North

2000


10

Professional Committees:

Member

Current

• International Bone and Mineral Society

• International Society for Study of Fatty Acids and Lipids

• New Zealand Nutrition Society

• Australia and New Zealand Bone and Mineral Society

Committee Member

1997-1999 • Executive Committee: National Osteoporosis Foundation, South

Africa

1998-1999 • Executive Committee: Society for Endocrinology, Metabolism and

• Diabetes of South Africa

Community Service

Talks on selected topics

2006 Arthritis Foundation of New Zealand Nutrition and

Osteoporosis

2005/

2006

Arthritis Foundation of New Zealand Nutrition and Arthritis

2006 Aokautere Women’s Group Osteoporosis

2005 What’s Hot in Nutritional Science The Female Triad

2003 Reformed Church of Palmerston North Osteoporosis and Arthritis

2002 Sports Science New Zealand Ergogenic Aids

General

1992 –

1999

Convenor and Judge, Finals, Science Expo South Africa

2002 –

2003

Judge, Science Expo

Palmerston North,

New Zealand

Committees

2008 -

present

Chair: Status of Women Committee, Zonta

International Manawatu

2003 –

2005

2001 -

Present

Secretary, Zonta International Manawatu

Member, Zonta International Manawatu

Zonta is an international

service organisation

committed to improving the

status of women.


11

Referees:

Prof PJ Moughan

Director: Riddet Institute

Massey University

Private Bag 11 222

Palmerston North

Tel: 06 350 5560

Email: [email protected]

Prof Annamarie Kruger

Director

AUTHeR (Africa Unit for Transdisciplinary Health Research)

Faculty of Health Science

North-West University

Potchefstroom Campus

Private Bag X 6001

Potchefstroom

2520

Tel: +27 18 299 2095

Fax: +27 18 299 2088

Email: [email protected]

Prof HH (Esté) Vorster Research Professor, Centre of Excellence for Nutrition (CEN)

Faculty of Health Sciences

North-West University (Potchefstroom Campus)

Private Bag X 6001

Potchefstroom

2520

Tel: + 27 18 299 4237

Fax: +27 18 299 2464

E-mail: [email protected]

mailto:[email protected]



APPENDIX I

RESEARCH EXPERIENCE

• Research Grants (Estimated Value)

• Research Contracts

• Achievements in Research

- Peformance Based Research Funding

- Editorials, Boards, Referee for Journals

- Research Funding Applications/Assessments of Scientists

- Consultancies

- Committees

• Speaking Invitations

- Invited Speaker

• Visits to International Laboratories

• International Conferences Attended with Poster/Oral Presentations

• International Meetings Attended (No Presentation)

Marlena Kruger Appendix I

APPENDIX I

RESEARCH EXPERIENCE

RESEARCH GRANTS (ESTIMATED VALUE)

2010 MRC South Africa (Co-applicant) $60,000

2009 MRC South Africa (Co-applicant) $60,000

2009 Sanpad(Co-applicant) $120,000

2007- 2009 National Research Foundation South Africa $25 000

2003 · Palmerston North Medical Research Foundation $5,000

2003 · Massey University Agricultural Research Fund $5,950

2002 · Massey University Research Fund $6,000

2000 · South Africa Medical Research Council R25,000

1999 · National Research Foundation South Africa R25,000

1999 · Hendrik Verwoerd Research Trust R90,000

1999 · Thrip R20,000

1998 · Anglo American/ De Beers Chairman’s Fund R30,000

1996 – 1997 · Anglo American/ De Beers Chairman’s Fund R50,000

1996 – 1999 · NIH Fogarty Grant (Prof K Wang, Co-worker) USD20,000

1996 – 1998 · South Africa Medical Research Council R30,000

1994 – 1996 · South Africa Medical Research Council R25,000

1992 – 1998 · Research Committee, University of Pretoria R10,000/yr

1992 South Africa Sugar Association R8,000

RESEARCH CONTRACTS

2009-2010 Seperex Nutritionals NZ; Bioactives for bone health $200,000

2009-2013 Plant and Food,/ Foundation for Research and

Technology, “New Berries”.

$1,000,000

2004 – 2008 · HortResearch/ Foundation for Research and

Technology (subcontractor “Healthful Berries”)

$75,000/year

2004 – 2007 · Meat Biologics Consortium (bioactives from meat

byproducts)

$150,000/year

2003 + 2006 · LactoPharma, New Zealand (bioactives from milk)

$100,000

2000 – Ongoing · Fonterra Brands Asia Limited $ 500,000 per

year ongoing

1994 – 1996 · Menorest – Osteoporosis (Rhone-Poulenc Rhorer,

France)

R500,000

1994 – 1998 · Phase II and III trials on the effect of essential fatty

acid supplementation in senile osteoporosis(Scotia

Pharmaceuticals Pty Ltd, UK) Animal trials using

OVX rat model to investigate the role of essential

fatty acids in prevention of osteoporosis

R2,000,000


ACHIEVEMENTS IN RESEARCH

Performance based research NZ

2007 PBRF rating: A

2006 · Reappointed: Panel Member, Performance Based Research

Funding, Health Panel, Ministry of Education, New Zealand

2005 · PBRF Consultation Committee

2004 · PBRF rating: B

2004 · Director of Research,

Institute of Food Nutrition and Human Health,


2004 · Reviewer/Consultant; Performance Based Research Funding,

Health Panel, Ministry of Education, New Zealand

2003 – 2004 · Panel Member, Performance Based Research Funding,

Health Panel, Ministry of Education, New Zealand

Editorial Boards, Referee for Journals:

2009- ongoing Member: Editorial Board “Nutrition Research”

2004- ongoing · Associate Editor; “Journal of the Science of Food and

Agriculture”

2003 · Guest Editor: Prostaglandins, Leukotrienes and Essential

Fatty Acids, Special edition on “The role of dietary fat

in bone and joint health”

2001 – Current · Editorial Board: Prostaglandins, Leukotrienes and

Essential Fatty acids

Journals: Journal of Nutritional Biochemistry

• American Journal of Clinical Nutrition

• Bone

• Biochem Biophys Acta: Molecular and Cell Biology

• Prostaglandins, Leukotrienes and Essential Fatty Acids

• Journal of Nutrition

• British Journal of Nutrition

• European Journal of Clinical Nutrition

• Osteoporosis International

• Calcified Tissue International

• Journal of Bone and Mineral Research


ACHIEVEMENTS IN RESEARCH ctd

Research Funding Applications/Assessment of Scientists:

2011 • Reviewer; Health Research Council, New Zealand

2010 • Expert reviewer, European Commission, FP7 funding round

2009 External Referee, Promotion to Associate Professor, North West

University, South Africa

2007 • Reviewer; Health Research Council, New Zealand

2006 • Performance Based Research Funding, panel member “Health”

2006 • BBSRC, UK

2006 • External referee – application for tenure, University of Toronto,

Canada

2005 • External referee – application for promotion to Associate Professor,

University of South Australia, Adelaide, Australia

2004 • Wellcome Trust (UK)

2004 • Irish Research Foundation

2003 • Tertiary Education Commission, New Zealand;

• Performance Based Research Funding, panel member “Health”

1997 – Ongoing • National Research Foundation, South Africa

1998 • Medical Research Council, South Africa

Consultancies:

2009 - ongoing • Seperex Nutritionals Ltd

2004 – 2009 • New Zealand King Salmon Limited

2000 – Ongoing • Fonterra Brands Limited

1996 – 1998 • Scotia Pharmaceuticals Pty Ltd, UK

Committees:

2009-ongoing • Chair: College of Sciences Professorial Forum

2008 - ongoing • Member; College of Sciences Promotions Committee

2008- ongoing • Member of Grant Development Fund committee

2008-ongoing • Professorial Promotions Review Committee

2006 - ongoing • DVC-Research Representative, Doctoral Research Committee,

Massey University

1997 – 1999 • Member: Animal Ethics Committee, University of Pretoria

1997 – 1999 • Member of Research Committee, Faculty of Medicine,

University of Pretoria, South Africa


SPEAKING INVITATIONS

Invited Speaker:

2010 • Key note address; Satellite symposium on bone density measured

using quantitative ultrasound. International Osteoporosis Foundation,

Regional Conference, Singapore.

2010 • Key note address: Bioactives for Bone Health; International

Symposium on Colostrum Basic protein, Beijing, China.

2009 • Key Note address: The benefits of Whey Protein in the diet;

International Conference on Whey Protein, Jantai, China

2007

2006

• Key Note address: Long chain polyunsaturated fatty acids and bone

health: epidemiological and human data; Combined Australian and

New Zealand Nutrition society meeting, Auckland New Zealand.

• Presentation: “Long chain polyunsaturated fatty acids affect bone

maintenance in humans and rats and these effects are possibly due to

modulation of specific molecular signalling events”; DSM Nutrition

International, Rheinfelder, Germany.

2006 • Keynote address: “ LCPUFA and osteoporosis: epidemiological and

human data”; International Society for the Study of Fatty Acids and

Lipids, Cairns, Australia

2005 • Keynote address: “Bone Health through the Life Cycle”;

International Union of Nutritional Sciences

(September) Durban, South Africa

2005 • 3rd International conference on Bone and Mineral Research; 5th

International Osteoporosis Symposium

(May) Xi’an China

2004 • Dept of Health Sciences, University of South Australia on lipids and

bone health

2004 • IFNHH Road Show on “Omega 3 health benefits”,

New Zealand

2002 • Experimental Biology 2002, New Orleans, USA on the role of dietary

lipids in the prevention of osteoporosis

1999 • Milk and Health Research Centre, New Zealand on role of essential

fatty acids in bone health

1998 • Nutrition in the News, Sun City, South Africa on Nutrition and

osteoporosis

1997 – 1998 • Merck, Sharp, Dohme CME lectures on Osteoporosis

• European Calcified Tissue, Harrogate, UK on Lipids and Bone

Health

• Hoffman La Roche, USA, leading round table discussion on lipids and

bone health Dept of Biochemistry, Cornell Medical School, USA

1996 • BIOLIFE Pty Ltd, Malaysia/Singapore on Nutrition and Bone

Health.

TV Channel 3, Malaysia interview on risk factors for osteoporosis,

treatment and prevention

1995 • Radio Metro, South Africa on Evening Primrose oil and skin

maintenance


1993, 1995 • Scotia Pharmaceuticals, Guildford, UK on the role of essential fatty

acids in bone health

VISITS TO INTERNATIONAL LABORATORIES

Prof A Kruger Faculty of Health Sciences, North-West University

Sabbatical; PURE-Bone study 2010

Prof HH Vorster Faculty of Health Sciences, North-West University

Sabbatical – investigating urbanisation and risk for CVD 2005

Prof Peter Howe

Dr John Buckley

Dept of Molecular and Biosciences

University of South Australia.

• Presentation of research,

Discussions on setting up collaborative work.

2004

Dr Alison Bendele University of Denver

Denver, Colorado, USA.

• Investigation into model of osteoarthritis.

2002

Prof B Watkins Dept of Food Science

Purdue University

La Fayette, USA.

• Lipids and bone.

2000

Prof C Weaver Dept of Nutrition,

Purdue University

La Fayette, USA.

• Kinetics of calcium absorption.

2000

Prof H DeLuca Dept of Biochemistry,

University of Wisconson in Madison

USA.

• Measurement of intestinal vitamin D receptor, using

ELISA and HAP assays.

1997

Prof L Raisz Division of Endocrinology and Metabolism

School of Medicine, University of Connecticut

Health Center

Connecticut, USA.

• Measurement of prostaglandins synthesis, mRNA

expression of cyclo-oxygenase 1 and 2, culture of

various cell lines and cells isolated from mouse calvaria.

1997

Dr Peter Weber Hofmann-La Roche

New Jersey, USA.

• Essential fatty acids in health and disease.

1997

Prof R McCarter Dept of Physiology, University of Texas Health Center

San Antonio, Texas USA.

• Muscle Dystrophy, Titin and Nebulin

1997

Prof S Epstein Albert Einstein Medical Centre, Temple University,


Pensylvania, USA

• mRNA extraction from bone, probing for growth factors

and cytokines

1995

Dr C Buck Dept of Urology, Glasgow Royal Infirmary

Glasgow, Scotland.

The role of fatty acids in prevention of renal stones

1994/5

Dr DF Horrobin Scotia Pharmaceuticals

Guildford, London, UK.

• Specialist lectures

1993

1995

Prof R Bouillon Laboratory for experimental medicine and

endocrinology

Leuven, Belgium.

• Vitamin D measurements

• Inverted gut sac procedure

• Rat bone density measurement, estrogen implants

1992

1995

1997

Dr F Grohovaz CNR Center of cytopharmacology. DIBIT,

Institute Raffaele, Milan.

• Measurement of intracellular calcium

1994

Dr D Pansu Laboratory for Physiology and Mineral exchange

Edouard Herriot Hospital

Lyon, Cedex, France.

• Calcium absorption and intestinal calcium binding

protein

1992

INTERNATIONAL CONFERENCES ATTENDED WITH POSTER/ORAL

PRESENTATIONS

2010 • International Osteoporosis Foundation, regional conference,

Singapore

2010 • International Society for the study of Fatty Acids and Lipids,

Maastricht, The Netherlands

2009 • International Conference on Nutritional Aspects of Osteoporosis,

Lausanne, Switzerland

2008

2007

2006

• European Calcified Tissue

Barcelona, Spain

• American Bone and Mineral Society,

Montreal, Canada

• International conference on the role of nutrition in osteoporosis,

Lausanne, Switserland.

2006 • European Calcified Tissue, Prague.

2005 • 3rd

International conference on Bone and Mineral Research; 5th

International Osteoporosis Symposium Xi’an China

2004 • International Society for the Study of Fatty Acids and Lipids Brighton, UK


2003 • International Bone and Mineral Society Osaka Japan

2002 • Experimental Biology 2002 New Orleans, USA

2001 • International Dairy Federation Auckland, New Zealand

1999 • European Calcified Tissue Maastricht, The Netherlands

1997 • European Calcified Tissue Harrogate, UK

1996 • British Bone and Tooth Society Manchester, UK

• World Congress on Osteoporosis Amsterdam, The Netherlands

1995 • Scotia Pharmaceuticals Guildford, Surrey, UK. Closed Conference

• British Bone and Tooth Society Warwick, UK

• International Society for the Study of Lipids and Fatty Acids

2nd International Conference Washington DC, USA

1994 • 9th Conference on Prostaglandins and related compounds Florence, Italy

1993 • 23rd European Symposium on Calcified Tissue Heidelberg, Germany

• Scotia Pharmaceuticals Calcium Workshop Guildford, London, UK

1990 • 34th Annual Meeting of the American Biophysical Society Baltimore, Maryland, USA

• 30th Annual Conference of the American Society for Cell Biology San Diego, USA

1986 • 6th International Conference on Prostaglandins and Related

Compounds Florence, Italy

• Annual Conference of the South African Biochemical Society

1985 • International Symposium on Membranes and Muscle

(IUB Symposium 136) South Africa

1983 • 29th Congress of the International Union of Physiological Sciences Sydney, Australia

INTERNATIONAL MEETINGS ATTENDED (NO PRESENTATION)

2004 • Australian Nutrition Society; Clinical Nutrition Brisbane, Australia

• 4th Orafti Conference “Feel-Good Factors for Health and Well-being” Paris, France

2003 • Australia and New Zealand Bone and Mineral Society


Hyatt, Coollum, Australia

2002 • Clinical Advances in Osteoporosis Honolulu, Hawaii, USA

2000 • World Congress on Osteoporosis Chicago, USA

• International Bone and Hormone Meeting Hamilton Island, Australia

1995 • 12th International Conference on Calcium Regulating Hormones Melbourne, Australia

• Steroids and Bone Coolum, Australia

1992 • 11th International Conference on Calcium Regulating Hormones Florence, Italy

1990 • 7th International Meeting on Prostaglandins and Related Compounds Florence, Italy

1989 • 29th Annual Meeting of the American Society for Cell Biology Washington DC, USA

1987 • German Physiological Society Annual Meeting Frankfurt, West Germany

1983 • 34th Annual Fall Meeting of American Physiology Society Honolulu, Hawaii

APPENDIX II

TEACHING EXPERIENCE

• Teaching Coordination

• Undergraduate Teaching

• Graduate Teaching

• External Examiner (Orals)

• Undergraduate and Graduate Students: Research Projects

- Students that progressed to completion (Chief Supervisor)

- Students that are in progress (Chief Supervisor)

• External Examiner (Postgraduate)

Marlena Kruger Appendix II

APPENDIX II

TEACHING EXPERIENCE

TEACHING COORDINATION

Massey University

• Coordinator Nutritional Biochemistry 2009-

ongoing

• Coordinator BSc Human Nutrition III

(Sports Nutrition)

2001 – 2007


• Coordinator MMed (Sports Science) 1995 – 1999

• Coordinator BSc III Exercise Physiology 1995 – 1999

• Coordinator BSc Honours ( Human Physiology)

1993 – 1999

UNDERGRADUATE TEACHING

Massey University

• Human Physiology BSc III 2007-

current

• Human Nutrition BSc III 2001 – 2004

• Sports Nutrition BSc III 2001 –

Ongoing


• Endocrinology MBChB 2nd

year 1992 – 2000

• Bone and Teeth Dental student 3rd

year 1998 – 2000

• Exercise Physiology BSc III 1994 – 1999

Medical University of Southern Africa:

• General Human Physiology MBChB 2nd

year 1980 – 1986

• Intermediary Metabolism Paramedics 1984 – 1986

GRADUATE TEACHING

Massey University

• Various topics in Human

Nutrition

MSc Nutritional Science 2001 –

Ongoing


• Faculty of Medicine; Research

Methodology

1998 – 2001


• Various topics in Physiology BSc Honours, MMed, MPhys Ther 1993 – 1999

EXTERNAL EXAMINER (ORALS)

• MBChB II (Physiology) University of the Free State

South Africa

1996 – 1997

• B Veterinary Nursing

(Physiology)


South Africa 1996 – 1997

UNDERGRADUATE AND GRADUATE STUDENTS: RESEARCH PROJECTS

Students that progressed to completion:

(Chief Supervisor)

PhD

2007 C Crooks • The effect of bovine colostrums supplementation on

levels of secretory IG-A in saliva of elite athletes, non-

exercising controls and non-exercising older adults.

2007

2006

R C Poulsen

M Walton

• Long chain PUFAs and their possible interaction with

phytoestrogens: impact on bone and bone cell function

in vivo and in vitro

• Berry Fruit anthocyanins in human nutrition –

bioavailability and antioxidant effects

2005 M Coetzee • The mechanism of action of fatty acids on bone cells:

an investigation into molecular signals for bone

formation and resorption

1996 N Claassen • The role of gamma-linolenic and eicosapentaenoic

acid supplementation in intestinal calcium absorption

and bone turnover

Masters

2009 J Taylor • Berry fruit and Asthma

2005 A Fear • The effect of pre- and probiotics on mineral balance

and bone density in the growing rat

2005 S Singh • The role of vegetables in bone health and regulation

of acid-base balance

2004 RC Poulsen • An investigation into the effects of omega-3 fatty

acids on bone resorption in the female OVX rat

2001 K Brown • Measurement of Bone Quality in growing male rats

using DEXA and bone ash content

2000 A Koorts • Intracellular calcium fluxes in the leucocytes of renal

failure patients (Co-Supervisor)


1999 H Vorster • The effect of urbanisation on bone loss and bone

density in the people of the North-West

1999 F Leonard • The role of essential fatty acids in modulation of the

vitamin D receptor

1997 CK Schlemmer • The influence of fatty acids on the balance between

• ectopic and bone calcification in the adult rat

1996 I Swart • The effect of MCT and CHO and L-Carnitine

supplementation on the performance andmetabolic

responses of marathon athletes

Students that progressed to completion:

BSc Honours

2008 J Hiess • The effect of plant extracts Grape seed, Quercetin and

rosehip on osteobalst proliferation and osteoclast

formation and activity.

1999 O Magada • Loss of oestrogen induces ectopic calcification

1997 NT Snyman • Reactive oxygen species, superoxide dismutase and

total antioxidant status in normozoospermic semen

samples

1997 EA le Roux • The effect of L-carnitine, chromium picolinate and

hidroxycitric acid on performance of female marathon

athletes

1997 F Vermeulen • Calcium transport in rat duodenum: effect of calcium

channel blockers, calmodulin antagonists and anti-

microtubular agents)

1997 A Koorts • Measuring intracellular calcium concentrations by

using the fluorescent calcium indicator fura-2

1996 S du Preez • The influence of seminal plasma morphology and

alpha-glucosidase enzyme activity on sperm zona

pellucida binding in infertile patients

1995 JH Kotze • The effect of nifedipine and lithium chloride on the

absorption of calcium in the rat duodenum.

1995 I Swart • The effect of L-carnitine supplementation on the VO2

max of marathon athletes

1994 W Stolze • Calcium-binding protein 28kD: Purification and

quantification; Role of essential fatty acid

supplementation

1993 DJ Rossouw • Purification of calcium-binding protein from rat kidney

BSc Med Sci III


1999 A Hattingh • The relationship between anxiety disorders, serum

cortisol and bone density

1999 Z van Jaarsveld • The effect of glucocorticoids on bone

Students that are in progress:

(Chief Supervisor)

PhD

2010 - C Gunn Vegetables and Bone Health

2009 - D Rankin P-M osteoporosis in the Manawatu region

2009- A Pranpravit Antioxidant status and metabolic syndrome

2008 - H McKinnon Goat milk and bone biomechanics

EXTERNAL / INTERNAL EXAMINER (POSTGRADUATE)

2008 C Bell • PhD Massey University

2008 K Dittmer • PhD Massey University

2008 RA Sabi • MSc University of Pretoria,

South Africa

2007 PJW Naude • MSc University of Pretoria

South Africa

2007 - JJ Gandy • MSc University of Pretoria

South Africa

2004 - AD Cromarty • PhD University of Pretoria

South Africa.

2003 L Bang • MPhil University of Waikato

New Zealand

2002 GK Joone • MSc University of Pretoria

South Africa

1998 L Malan • MSc North-West University

South Africa

1995 JS Brits • PhD North-West University

South Africa

1995 JDR Reichel • MSc North-West University

South Africa

1994 M Meyer • MSc North-West University

South Africa

APPENDIX III

PUBLICATIONS

• Book Chapter/ Theses

• Peer Reviewed Publications

• Peer Reviewed Abstracts

Marlena Kruger Appendix III

APPENDIX III

PUBLICATIONS

Note: Postgraduate students are usually listed as first author; as project leader/

coordinator responsible for research and obtaining funding, I am listed last.

Book Chapters/Theses:

1) Kruger MC and Poulsen RC. Synergy of protein, fats and calcium; potential

synergies with drugs for osteoporosis. In Food-Drug Synergy and Safety.

Thompson LU and Ward WE (eds.) CRC Press, Boca Raton, FL. pp. 255-283,

2005

2) M Haag, MC Kruger (2002) Endocrine System. In Human Physiology, pp18.1-

18.70. Meyer, BJ, Van Papendorp DH, Meij HS, Viljoen eds. Juta Press, Cape

Town, South Africa.

3) MC Kruger. "The effect of unsaturated fatty acids on calcium transport in skeletal

muscle sarcoplasmic reticulum". PhD Thesis, Medical University of Southern

Africa, 1986.

Peer Reviewed Publications:

1) N T Malan and M Pieterse. "Sarkoplasmiese retikulum en Spierkontraksie".

(i) Geneeskunde 21 4 (1977) 74-76; (ii) Geneeskunde 21 5 (1977) 90-93.

2) M Kruger and J Booyens. "The effect of the prostaglandin derivative PGBx on

calcium uptake and release by skeletal muscle sarcoplasmic reticulum". SA Med

J 62 (1982) 855-858.

3) M Kruger, J Booyens and N T Malan. "Some factors affecting calcium transport

through skeletal muscle sarcoplasmic reticulum". SA J of Science 81 (1984) 406.

4) M Kruger, J Booyens and N T Malan. "Unsaturated fatty acids and calcium

transport through isolated skeletal muscle sarcoplasmic reticulum" in Membranes

and Muscle (IUB Symposium 136), Berman, Gevers and Opie, Cape Town eds

(1985).

5) M Kruger, J Booyens and N T Malan. "Some effects of arachidonic acid on

isolated sarcoplasmic reticulum vesicle membranes during calcium transport.

IRCS Med Sci 14 (1986) 23-24.

6) M Kruger, J Booyens and N T Malan. "A biochemical analysis of the effects of

arachidonic acid on sarcoplasmic reticulum function". Prostaglandins,

Leukotrienes and Essential Fatty Acids 33 (1988) 41-47.


7) M Kruger, J Wright and K Wang. "Nebulin as a length regulator of thin filaments

of vertebrate skeletal muscles: correlation of thin filament length, nebulin size and

epitope profile. J of Cell Biology 115 (1991) 97-108.

8) M Kruger, J Wright and K Wang. "Nebulin as a length regulator of thin filaments

of vertebrate skeletal muscles. In: The Role of Isoform diversity in cytoskeletal

functions" (1991). Cold Spring Harbor Laboratory, NY.

9) B J Meyer, D H van Papendorp, M J Pitout and M C Kruger. Vrugtedieet, 'n

gesonder lewenstyl. Geneeskunde 35 (4)(1993) 3-11.

10) D H van Papendorp, H Coetzer and M C Kruger. Biochemical profile of

osteoporotic patients on essential fatty acid supplementation. Nutrition Research

15 (3) (1995) 325-334.

11) H Coetzer, N Claassen, D H van Papendorp, M C Kruger. Calcium transport by

isolated brush border and basolateral membrane vesicles: role of essential fatty

acid supple-mentation. Prostaglandins, leukotrienes and essential fatty acids 50

(1994) 257-266.

12) N Claassen, H Coetzer, D H van Papendorp & M C Kruger. Passive intestinal

calcium transport and its significance in the development of the rat. Laboratory

Animals 29 (1995) 438-441.

13) JC Seegers, LH Böhmer, MC Kruger, M-L Lottering, M de Kock. A comparative

study of Ochratoxin A-induced apoptosis in hamster kidney and HeLa cells.

Toxicol Appl Pharmacol 129 (1994) 1-11.

14) N Claassen, HC Potgieter, M Seppa, WH Vermaak, H Coetzer, DH van Papendorp

& MC Kruger. Supplemented gamma-linolenic acid and eicosapentaenoic acid

inhibit bone turnover in young male rats: effects on free urinary collagen

crosslinks, total Hydroxyproline and bone calcium content. Bone 16 (4)(1995)

385S-392S.

15) MC Kruger, H Coetzer, R de Winter & N Claassen. Eicosapentaenoic acid and

docosahexaenoic acid supplementation increases calcium balance. Nutrition

Research 15 (2) (1995) 211-219

16) N Claassen, H Coetzer, CML Steinmann & MC Kruger. The effect of different n-

6/n-3 ratios on calcium balance and bone in rats. Prostaglandin Leukot and

Essent Fatty acids 53 (1995) 13-19.

17) DH van Papendorp, JJ Theron, M Viljoen, MC Kruger & ME Steyn. Plasma

melatonin levels in patients with spinal cord lesions. Medical Science Res 23

(1995) 189-190.


18) MC Kruger, GJ Gericke, JC van Dyk, DH van Papendorp. Are biochemical

markers of bone turnover of any significance to evaluate growth and bone

development in typeI Diabetes Mellitus? Geneeskunde 5 (1996) 14-23.

19) N Claassen, H Coetzer, CML Steinmann & MC Kruger. The effect of different n-

6/n-3 ratios on calcium balance and bone in rats. Infant Nutrition Digest 1 (1997)

10-12

20) N Claassen, H Coetzer, R de Winter, M Haag, MC Kruger. Relationship

between duodenal calcium uptake and calcium-magnesium ATPase activity.

Medical Science Research 24 (12) (1996) 809-811.

21) I Swart, J Rossouw, JM Loots, MC Kruger. The effect of L-carnitine

supplementation on plasma carnitine levels and various performance

parameters of male marathon athletes. Nutrition Research 17 (3) (1997) 405-

414.

22) TC Viljoen, N Claassen, H Coetzer, DH van Papendorp, MC Kruger. Putative

oestrogen receptors in rat duodenal cells. Med Sci Res 25 (1997) 197-199.

23) MC Kruger, DF Horrobin. Essential fatty acids, calcium and osteoporosis; a

review. Progress in Lipid Res 36 (2/3)(1997) 131-151.

24) MC Kruger, CM Smuts, N Claassen, H Potgieter. Correlation between essential

fatty acids and parameters of bone turnover. Asia Pacific J Nutr 6 (4)(1997) 235-

238.

25) MC Kruger, R de Winter, DH van Papendorp, GJ Gericke. Fatty acid

supplementation in senile osteoporosis. Ageing: Clinical and Experimental

Research 10 (5) (1998) 385-394.

26) CK Schlemmer, H Coetzer, N Claassen, MC Kruger, C Rademeyer, L van

Jaarsveld, Cm Smuts. Ectopic calcification of rat aortas and kidneys is reduced

with n-3 fatty acid supplementation. Prostaglandins, Leukotrienes and Essent

Fatty Acids (59) (3) (1998) 221-227.

27) M Haag, O Magada, F Vermeulen, MC Kruger. Polyunsaturated fatty acids inhibit

Mg-ATPase in basolateral membranes from rat entererocytes. Prostaglandins,

Leukotrienes and Essent Fatty Acids (61) (1) (1999) 221-227.

28) PJ du Toit, J Lunsky, B van Vuuren, J van Heerden, MC Kruger, CML Steinmann.

Hand-eye co-ordination of cricket players after short period of exercise. African

Journal for Physical, Health Education, Recreation and Dance (5) (2) (1999)

160-168.

29) CK Schlemmer, H Coetzer, N Claassen, MC Kruger. Oestrogen and essential fatty

acid supplementation corrects bone loss due to ovariectomy in the female Sprague

Dawley rat. Prostaglandins, Leukotrienes and Essent Fatty Acids

(61)(6)(1999) 381-390.


30) Haag, O Magada, F Vermeulen, MC Kruger. Inhibition of duodenal enterocyte

Magnesium ATPase is not mediated by protein kinase C. Prostaglandins,

Leukotrienes and Essent Fatty Acids (62) (3)(2000) 183-187

31) DH van Papendorp, MC Kruger, C Maritz, NG Dippenaar. Action potential

simulation therapy self assessment by 285 patients with pain. Geneeskunde

Jan/Feb (2000) 18-24

32) AM Koorts, MC Kruger, M Viljoen. Die bepaling van intrasellulere vry kalsium

in die neutrofiel met die fluoressente kalsium indikators Fura-2 and Fura-PE3.

Suid Afrikaanse Tydskrif vir Wetenskap en Tegnologie (2000)19 (3,4) 96-10

33) M Haag, MC Kruger. Upregulation of duodenal calcium absorption by poly-

unsaturated fatty acids: events at the basolateral membrane. Medical

Hypotheses 56 (5) (2001) 637-640

34) F Leonard, MC Kruger. Modulation of intestinal vitamin D receptor

availability and calcium ATPase activity by essential fatty acids.

Prostaglandins, Leukotrienes and Essent Fatty Acids 64 (2001)(3): 147-

150

35) M Haag, SD Kearns, ON Magada, PR Mphahla, N Classen, MC Kruger

Effect of arachidonic acid on duodenal enterocyte ATPases.

Prostaglandins and other Lipid Mediators (2001)(66) 53-63

36) HS Gill, ML Cross, AJ Darragh, BG Gallaher, MC Kruger. Milk, more than just a

food: health benefits. Food Industry Journal (2001) 4 (3): 230-250

37) MC Kruger. Nutrition and arthritis. Dialogue (2001) 38:8-11

38) AM Koorts, M Viljoen, MC Kruger, CD Potgieter. Intracelluler free calcium in

the neutrophils of maintenance haemodialysis patients. Clinical Physiology and

Functional Imaging (2002) 22 (4): 285-294

39) MC Kruger, AM Koorts, M Viljoen. Red blood cell fatty acid profile of chronic

renal failure patients receiving maintenance haemodialysis treatment.

Prostaglandins, Leukotrienes and Essent Fatty Acids (2002) 67 (1): 13-18

40) HH Vorster, CS Venter, MC Kruger, HS Kruger. The impact of urbanisation on

risk factors for osteoporosis in Black postmenopausal South African women.

Journal for Endocrinology, metabolism and diabetes of Southern Africa

(2002) 7 (3): 92-99

41) MC Kruger, R de Winter, PJ Becker, HH Vorster. Changes in bone markers of

bone turnover with urbanisation in Black South African Women. South African

Journal for Clinical Nutrition (2003) 16 (3): 103-108

42) MC Kruger, KE Brown, G Collett, L Layton, LM Schollum. The effect of


fructooligosaccharides with various degrees of polymerisation on calcium

bioavailability in the growing rat. Experimental Biology and Medicine (2003)

228 (6): 683-688

43) M Haag, ON Magada, N Claassen, LH Bohmer, MC Kruger. Omega 3 fatty acids

modulate ATPases involved in duodenal calcium absorption.: Prostaglandins,

Leukotrienes and Essential Fatty Acids (2003) 68 (6): 423 – 429.

44) MC Kruger, B Gallaher, LM Schollum. Bioavailability of calcium is equivalent

from milk fortified with either calcium carbonate of milk calcium in growing male

rats. Nutrition Research (2003) 23: 1229-1237

45) MC Kruger, R de Winter, PJ Becker, HH Vorster. Changes in bone markers of

bone turnover with urbanisation in Black South African Women. Journal of

Endocrinology, Metabolism and Diabetes of Southern Africa 2004 9 (1): 8-14

(reprinted from SAJCN)

46) M Coetzee, MC Kruger. Osteoprotegerin/ RANKL ratio: a new approach to

osteoporosis treatment? Southern Medical Journal (2004) 97: 506-511

47) HA Weiler, MC Kruger. Polyunsaturated fatty acids and bone mass. Am J Clin

Nutr (2004) 80: 1085-1086.

48) R Lentle, MC Kruger. Changes in the mineralization and biomechanical properties

of tibial metaphyseal bone in rats after three weeks immobilisation in a functional

position without compression. Journal of Applied Physiology (2005) 99: 173-

180.

49) MC Kruger, GG Plimmer, LM Schollum, N Haggarty, S Ram, K Palmano. The

effect of whey acidic protein fractions on bone loss in the ovariectomised rat.

British Journal of Nutrition (2005) 93: 244-252

50) MC Kruger, LM Schollum. Is docosahexaenoic acid more effective than

eicosapentaenoic acid for increasing calcium bioavailability? Prostaglandins,

Leukotrienes and Essential Fatty Acids (2005) 73: 327-334

51) MC Kruger. Bone health from adolescent to adult: effects of urbanisation.

Proceedings of the 18th

International Congress of Nutrition – Nutrition safari

for Innovative solutions. 19-23 September (2005), Durban, South Africa. Ed:

Vorster HH et al. ISBN 3-8055-8015-0

52) M Coetzee, M Haag, MC Kruger. Stimulation of prostaglandin E2 production by

arachidonic acid, oestrogen and parathyroid hormone in MG-63 and MC3T3-E1

osteoblast-like cells.Prostaglandins, Leukotrienes and Essential Fatty Acids

(2006) 73: 423-430

53) MC Kruger, Poulsen RC, Schollum LM, Haggarty, N., Palmano, K. A comparison

between various protein fractions from whey or milk for prevention of bone loss

in the female ovariectomised rat. International Dairy Journal (2006) 16: 1149-

1156


54) RG Lentle, MC Kruger, DJ Mellor, PJ Moughan. A morphological assessment of

limb development in pouch young of the brush-tail possum, Trichosurus vulpecula

and tammar wallaby Macropus eugeni. British Journal of Zoology (2006) 270:

122-131.

55) MC Kruger, LM Schollum, B Kuhn-Sherlock, CL Booth, Jane Coad, M Shearer.

The effect of calcium fortified milk supplementation with or without vitamin K1

on biochemical markers of bone resorption and formation in premenopausal

women.: Nutrition (2006) 22: 1120-1128.

56) M Walton, RG Lentle, G Reynolds, MC Kruger, T McGhie. Investigation of

anthocyanin absorption and antioxidant status in pigs. J Agric Chem (2006) 54:

7940 – 7946.

57) RC Poulsen. MC Kruger. Detrimental effect of eicosapentaenoic acid

supplementation on bone following ovariectomy in rats. Prostaglandins, Leukot

Essent Fatty Acid (2006) 75: 419-427.

58) M Coetzee, M Haag, AM Joubert, MC Kruger. Effect of Arachidonic Acid,

Docosahexaenoic Acid and Prostaglandin E2 on Cell Proliferation and

Morphology of MG-63 and MC3T3-E1 Osteoblast-like Cells. Prostaglandins,

Leukot Essent Fatty Acid (2007) 76: 35-45.

59) M Coetzee, M Haag, MC Kruger. Effects of Arachidonic Acid, Docosahexaenoic

Acid, Prostaglandin E2 (PGE2), and Parathyroid Hormone on Osteoprotegerin

(OPG) and RANKL Secretion by MC3T3-E1 Osteoblast-like Cells. Journal of

Nutritional Biochemistry (2007) 18: 54-63.

60) T McGhie, M Walton, L Barnett, H Martin, MC Kruger. Boysenberry and

blackcurrant drinks increased the plasma antioxidant capacity in an elderly

population but had little effect on other markers of oxidative stress. J Science

Food Agric (2007) 87: 2519-2527

61) RC Poulsen, EC Firth, CW Rogers, PJ Moughan, MC Kruger. Specific effects of

gamma-linolenic, eicosapentaenoic acid and docosahexaenoic ethyl esters on bone

post-ovariectomy in rats. Calcif Tissue Int (2007) 81: 459-471.

62) RC Poulsen, PJ Moughan, MC Kruger. Long chain fatty acids and the regulation

of bone metabolism. Exp Biol. Med (2007) 232 (10): 1275 - 1288.

63) RC Poulsen, FM Wolber, PJ Moughan, MC Kruger. Long chain polyunsaturated

fatty acids alter membrane bound RANK-L expression and osteoprotegerin

secretion by MC3T3-E1 osteoblast-like cells. Prostaglandin Lipid Mediators

(2008) 85:42-48.

64) RC Poulsen, PJ Moughan, MC Kruger. Docosahexaenoic acid and 17-beta

estradiol co-treatment is more effective than 17-beta estradiol alone in maintaining

bone post-ovariectomy in rats. Exp Biol Med (2008) 233: 592-602.


65) MC Kruger, W-H Chua, A Darragh, CL Booth, C Prosser, D Lowry. Impact of

goat milk powdered formulations on mineral absorption, peak bone mass and bone

loss due to ovariectomy in rats. J Sci Food Agric (2008) 88: 1082-1090..

66) RC Poulsen, MC Kruger. Soy phytoestrogens: impact on post-menopausal bone

loss and mechanisms of action. Nutrition Reviews (2008) 66 (7): 359-374.

67) RC Poulsen, KH Gotlinger, CN Serhan, MC Kruger. Identification of

inflammatory and proresolving lipid mediators in bone marrow and their lipidomic

profiles with ovariectomy and omega 3 intake. Am J Hematol (2008) 83: 437-

445.

68) PR von Hurst, W Stonehouse, C Matthys, C Conlon, MC Kruger, J Coad.

Metabolic syndrome, vitamin D and bone status in South Asian women living in

Auckland, New Zealand: a randomised, placebo-controlled, double-blind vitamin

D intervention. BMC Public Health (2008) 31 July 8:267 – 275

69) RC Poulsen, Du Toit Loots, PJ Moughan, MC Kruger. Ileal and fecal digestibility

of daidzein and genistein and plasma bioavailability of these isoflavones and their

bioactive metabolites in the ovariectomised rat. Mol Nutr Food Res (2009) 53:

S27-S35.

70) MC Kruger, A Fear W-H Chua, GG Plimmer, LM Schollum. The effect of

lactobacillus rhamnosus (HN001) on mineral absorption and bone health in the

growing male and ovariectomised female rat. Dairy Science Tech (2009) 89: 219-

231

71) M Coetzee, M Haag, MC Kruger. Effects of arachidonic acid and

docosahexaenoic acid on differentiation and mineralisation of MC3T3-E1

osteoblast-like cells. Cell Biochem Function (2009) 27: 3-11.

72) HL McKinnon, C Prosser, D Lowry, MC Kruger. The effect of formulated goats’

milk on calcium bioavailability in male growing rats. J Science Food Agric

(2010) 90: 112-116.

73) MC Kruger, LM Schollum , B Kuhn-Sherlock, A Hestiantoro, P Wijanto, J Li-Yu,

I Agdeppa, JM Todd, R Eastell. The effect of a fortified milk drink on vitamin D

status and bone turnover in post-menopausal women from South- East Asia. Bone

(2010) 46: 759-767.

74) PR Von Hurst, MC Kruger, J Coad. Vitamin D supplementation and markers of

bone turnover. J Steroid Biochem Mol Biol (2010) 121: 293-296

75) A Molan, Z Liu, MC Kruger. The ability of green tea to positively modulate key

markers of gastrointestinal function in rats. Phototherapy Res (2010) (In Press)

76) AL Molan, Z Liu, MC Kruger. The ability of blackcurrant extracts to positively

modulate key markers of gastrointestinal function in rats. World J Microbiol

Biotech (2010) 26: 1735-1743.


77) PR Von Hurst, MC Kruger, W Stonehouse, J Coad. Bone density, calcium intake

and vitamin D status in South Asian women living in Auckland, New Zealand.

Nutr Dietetics (2010) 67: 150 - 154

78) MC Kruger, M Coetzee, M Haag, H Weiler. Long-Chain fatty acids: Selected

mechanisms of action on bone. Prog Lipid Res (2010) 49: 439-449

79) I Angeles-Agdeppa, MV Capanzana, J Li-Yu, LM Schollum, MC Kruger. High-calcium

milk prevents overweight and obesity among postmenopausal women. Food Nutr Bull

(2010) 31(3):381-90

80) AL Molan, Z Liu, MC Kruger. The ability of blackcurrant extracts to positively

modulate key markers of gastrointestinal function in rats. World J Microbiol

Biotech (2010) 26: 1735-1743.

81) W Stonehouse, M Pauga, R Kruger, C Thomson, M Wong, MC Kruger.

Consumption of salmon versus salmon oil capsules - effects on omega 3 PUFA

and selenium status. Brit J Nutr (2011) 106: 1231-1239.

82) MC Kruger, IM Kruger, E Wentzel-Viljoen, A Kruger. Urbanisation of black

South Africa women may increase risk of low bone mass due to low vitamin D

status, low calcium intake and high bone turnover. Nutr Res (2011) 31: 748-758.

83) MC Kruger. Molecular mechanisms of action of vitamin K, vitamin D and

selected minerals on bone cells. Recent Res Devel Nutrition (2011) 8: 1-19.

84) DC Hunter, MA Skinner, FM Wolber, CL Booth, JMS Loh, M Wohlers, LM

Stevenson, MC Kruger. Consumption of gold kiwifruit reduces severity and

duration of selected upper respiratory tract symptoms and increases plasma

Vitamin C concentration in healthy older adults. Brit J Nutr (2012) in press.

85) I Kruger, MC Kruger, A Kruger. Cut-off values of distal forearm bone density for

the diagnosis of central osteoporosis in black postmenopausal women from South

Africa. JEMDSA (2012) in press

Peer Reviewed Abstracts:

1) M Kruger and J Booyens. "The effect of Prostaglandin Bx on calcium uptake,

release and ATPase activity in skeletal muscle sarcoplasmic reticulum" in

Proceedings of the 19th Congress of the International Union of Physiological

Sciences (1983) 45.

2) M Kruger, J Booyens and N T Malan. "The effect of arachidonic acid on the

function and structure of sarcoplasmic reticulum vesicles" in Proceedings of VIth

International Conference on Prostaglandins and related compounds.

Fondazione Giovanni, ed. Florence, Italy (1986) 288.

3) M Kruger, J Wright and K Wang. "Immunolocalization of nebulin in the

sarcomere matrix using monoclonal antibodies to four distinct epitopes".

Biophysical Journal 57 (1990) 554a.


4) M Kruger, J Wright and K Wang. "Immunolocalization of nebulin in the

sarcomere matrix of skeletal muscles". J of Cell Biol III, 5 (2) (1990) 428a.

5) M Kruger, J Wright and K Wang. Nebulin as a length regulator of thin filaments

of vertebrate skeletal muscles: Correlation of thin filament length, nebulin size and

epitope profile. J of Cell Biology 115 : 3,2 (1991) 180a.

6) MC Kruger, N Claassen, H Potgieter & DF Horrobin. The effects of GLA and

EPA on bone calcium and on urinary collagen crosslink excretion in young male

rats. Bone 17 (3) (1995) 327.

7) MC Kruger, N Claassen, HC Potgieter, H Coetzer, R de Winter. Essential fatty

acid supplementation and calcium retention in the ovariectomised rat. J Bone Min

Res 11 (10) (1996)

8) MC Kruger, N Claassen, H Coetzer, CM Smuts. Correlation between essential

fatty acids and parameters of bone formation and degradation. J Bone Min Res 11

(10) (1996)

9) MC Kruger, HC Potgieter, H Coetzer, R de Winter, DH van Papendorp. Calcium,

gammalinolenic acid and eicosapentaenoic acid supplementation in osteoporosis.

Osteoporosis Int 6 (1) (1996) 250.

10) MC Kruger, N Claassen, C Schlemmer, DH van Papendorp, HC Potgieter.

Essential fatty acids, calcium homeosrasis and bone turnover. Bone 20 (45) (1997)

121S.

11) MC Kruger, H Coetzer, N Claassen, C Schlemmer. Interactions between

oestrogen, fatty acids and calcium in the ovariectomised rat. Bone 20 (45) (1997)

28S.

12) MC Kruger, N Claassen, C Schlemmer, H Coetzer. Essential Fatty acid

supplementation: Effect of oestrogen deficiency induced bone loss in the female

rat. Calcified Tissue International 64 (1) (1999) S65

13) M Coetzee, MC Kruger. Arachidonic acid and bone active hormones induce

prostaglandin E2 synthesis in osteoblasts. JEMDSA (6) (1) (2001)

14) HH Vorster, CS Venter, HH Vorster, MC Kruger. The impact of urbanisation on

risk factors for osteoporosis in black postmenopausal women. Annals of

Nutrition and Metabolism 45 (suppl 1) (2001) 257

15) M Haag, F Vermeulen, O Magada, MC Kruger. Differential effects of arachidonic

acid on rat duodenal membrane ATPases. Journal of Endocrinology ,

Metabolsim and Diabetes 6 (2001) 45

16) MC Kruger, B Gallaher, LM Schollum. Is magnesium necessary for optimal

growth and calcium absorption: an investigation in the growing male rat. Bone 32

(5) (2003) S192


17) RC Poulsen, MC Kruger. Detrimental effect of high dose eicosapentaenoic acid

supplementation on bone density in ovariectomised Sprague Dawley rats. Asia

Pacific Journal of Clinical Nutrition (2004): S49

18) M Coetzee, M Haag, MC Kruger. Exposure of MC3T3-E1 osteoblasts to

polyunsaturated fatty acids modulates prostaglandin E2 synthesis and secretion of

osteoportegerin. JEMDSA 10 (1): 35

19) MC Kruger, LM Schollum, B Kuhn-Sherlock, CL Booth, Jane Coad, M Shearer.

The effect of calcium fortified milk supplementation with or without vitamin K1

on biochemical markers of bone resorption and formation in premenopausal

women. Bone 36 (2005): S429.

20) MC Kruger, G Plimmer, RC Poulsen, LM Schollum, N Haggarty, S Ram, K

Palmano. Acidic protein fractions from whey and milk limit bone loss in the

female ovariectomised rat. Bone 36 (2005): S429 – S430.

21) MC Kruger, LM Fray, W-H Chua, L Fremon. Long chain polyunsaturated fatty

acids affect cytokine and tyrosine kinase activity in MC3T3-E1 pre-osteoblast

cells. Calcif Tissue Int 78 (Suppl) 2006: S55

22) M Matuschek, MC Kruger, RG Lentle, G Reynolds, A Broomfield, CL Booth.

Investigation of anthocyanin absorption and antioxidant status in pigs. 4th

International workshop on anthocyanins, Rotorua, New Zealand.

23) M Coetzee, M Haag, MC Kruger. Exposure of MC3T3-E1 cells to arachidonic

acid, docosahexaenoic acid and parathyroid hormone modulates osteoprotegerin

and RANKL secretion. Calcif Tissue Int 80 (Suppl 1) 2007: S75.

24) RC Poulsen, MC Kruger. Additive and synergistic effects of 17beta-estradiol and

docosahexaenoic acid on bone postovariectomy in rats. J Bone Min Res 22 2007:

S321

25) MC Kruger. Long chain polyunsaturated fatty acids and bone health:

epidemiological and human data. Asia Pac J Clin Nutr 16 (suppl 3) 2007: S65.

26) AL Molan, MC Kruger. Tea and Bone health: a review. Proceedings of the New

Zealand Nutrition Society 31 (2007): 60-65.

27) AL Molan, MC Kruger, S De, LN Drummond. The ability of kiwifruit to

positively modulate key markers of gastrointestinal function. Proceedings of the

New Zealand Nutrition Society 31 (2007): 66-71..

28) M Coetzee, M Haag, MC Kruger. Effects of arachidonic acid and

docosahexaenoic acid on differentation of and mineralisation by MC3T3-E1

osteoblast-like cells. Calcif Tissue Int 82 (suppl) 2008: S100.

29) MC Kruger, LM Schollum, A Hestiantoro, K, Sumapraja, P Wijanto, W

Rositawati, W-H Chua, JM Todd. Bone density and calcium intakes in


postmenopasusal Indonesian women. Osteoporosis Int 20 (2009): 181

30) MC Kruger, LM Schollum, J Li Yu, W-H Chua, JM Todd. Bone mineral density

among postmenopausal Filipino women. Osteoporosis Int 20 (2009): 180.

31) MC Kruger, LM Schollum, A Hestiantoro, K, Sumapraja, P Wijanto, W

Rositawati, W-H Chua, JM Todd. Bone density and calcium intakes in

postmenopasusal Indonesian women..Bone 44 (2009): S108

32) MC Kruger, LM Schollum, J Li Yu, W-H Chua, JM Todd. Bone mineral density,

calcium intake and general health of a cohort of postmenopausal Filipino women.

Bone 44: (2009): S107.

33) MC Kruger, LM Schollum, B Kuhn-Sherlock, A Hestiantoro, P Wijanto. 16-week

supplementation with fortified milk improves vitamin D status and reduces bone

resorption and turnover in postmenopausal Indonesian women. Annals Nutr

Metabolism 55 (2009) suppl 1: 84.

34) MC Kruger, LM Schollum, JM Todd, B Kuhn-Sherlock, DW McLean, K Wylie.

Use of an ultrasound screening programme to undertand the risk of poor bone

health in Indonesian men and women. Osteoporosis Int 21 (2010) Suppl 5: S708.

35) MC Kruger, LM Schollum, JM Todd, B Kuhn-Sherlock, DW McLean, K Wylie.

Bone health comparison in seven Asian countries using heel ultrasound.

Osteoporosis Int 21 (2010) Suppl 5: S773.

36) A Kruger, MC Kruger, E Wentzel-Viljoen. Bone health of black South African

women in transition. SA J Clin Nutr 23(3) (2010) Supplement 2:S17

37) JC Boeyens, WH Chua, MC Kruger, AM Joubert, M Coetzee. In vitro effects of

popyunsaturated fatty acids on osteoclastogenesis and bone resorption in RAW

264.7 murine macrophages. Bone 48 (2011): S133

38) WH Chua, C Norris, C Loyd-West, B Kuhn-Sherlock, LM Schollum, MC Kruger.

Effect of a green tea extract on bone health and body composition in

ovariectomised Sprague Dawley rats. Osteoporosis Int 22 (2011) Suppl 4: S647

39) IM Kruger, MC Kruger, A Kruger. The effect of age on parathyroid hormone

levels and bone turnover in Black postmenopausal women. Osteoporosis Int 22

(2011) , Suppl 4: S656

40) MC Kruger, P Ha, J Todd, B Kuhn-Sherlock, E Lau, J Ma, G Quin, LM Schollum.

Bone minderal density, quantitative ultrasound measurement and calcium intake

among postmenpausal Chinese women. Osteoporosis Int 22 (2011): Suppl 4:

S618