Curriculum Vitae

Personal Information

First Name: Farina Hanif

Last Name: Muhammad Hanif

Date of Birth: 18/05/1983

Gender: Female

Nationality: Pakistani

Email: farina.hanif@hotmail. com & farina.hanif@duhs.edu.pk

Contact Number: 0312-1145372 & 0332-2632066

Contact Address: Institute of Biomedical Sciences, and Dow Research Institute of

Biological and Biomedical Sciences, Dow University of Health

Sciences, Ojha Campus, Karachi, Pakistan.

Education

Post-doctoral Training (2015 – 2016) Department of Biological and Biomedical Sciences, The Aga Khan University.

Ph.D. “Molecular Medicine”, (2015) PCMD, ICCBS, University of Karachi, Karachi, Pakistan.

Pre-doctoral Training (2013-2014) School of Biomedical and Health Sciences, King’s College London, University

of London, UK.

GRE Type Exam of “Molecular Medicine Cleared with 87 percentile (1st position)

M .Sc “ Physiology”, (2004; 1st Division) University of Karachi, Karachi, Pakistan.

B. Sc (Hons) “Physiology, Biochemistry & Chemistry”, (2002; 1st Division) University of Karachi, Karachi, Pakistan.

Professional Profile

Current Position: Assistant Professor, Pathology (Molecular) Current Research: To study the therapeutic potential of natural and synthetic

compounds against Glioblasatoma Multiforme, with the focus on

cancer stem cells

Affiliated Institution: Dow University of Health Sciences

Research Interests

To study and find out underlying molecular mechanisms involve in the aetiology and pathogenesis of complex diseases like cancers, epilepsy and Schizophrenia and further to identify the possible therapeutic targets.

Role of cancer stem cells in drug resistance

To analyse the therapeutic potential and mechanism of action of newly synthesized compound using disease models.

Also interested in educational research regarding use of new technologies that can aid in effective teaching and learning modalities.

Academic Positions

Position held:

Assistant Professor, Molecular Pathology (2016 to date) Dow University of Health Sciences.

Post-Doctoral Research Fellow (2015 to 2016) The Aga Khan University.

Visiting Researcher/Scholar (2013-2014) King’s College London, University of London, UK

Research Fellow (2009 to 2015) PCMD, ICCBS, UoK.

Research Associate (2007-2009) Involved in teaching and research related activities. Department of Biological and Biomedical Sciences, The Aga Khan University.

Teacher “Biology and Chemistry” (2005-2007) The SMS Aga Khan School.

Private Teaching (2002-2005)

Training

Ph.D. (2015) Thesis Title: In-vitro modulation of human glioblastoma cells (U87) by N-(2-hydroxy phenyl) acetamide.

Visiting Researcher Pharmaceutical Science Research Division, Dept. of

/Scholar (2013-2014) Biochemistry, School of Biomedical and Health Sciences, King’s College London, University of London, UK.

Fields of Specialties

Specialties:

Molecular Medicine (Pathology), Physiology, Molecular Neurology

Skills: (PCR) Polymerase Chain Reaction (both qualitative and quantitative), Genotyping, Primer Designing, DNA extraction, Gel Electrophoresis, Patch Clamping, Microscopy, Cell culture, Immunocytochemistry, immunohistochemistry Protein Expression and Purification, (Affinity chromatography, ion exchange chromatography, Gel filtration Chromatography) Cloning, site Directed Mutagenesis, Transformation, and sequencing.

Membership

International Brain Research Organization. (IBRO), Paris, France.

International Society for Neurochemistry (ISN)

Safety Pharmacology Society (SPS) USA.

Pakistan Society of Basic and Applied Neuroscience (PSBAN).

Patents Shabana U Simjee, Sabira Begum, Saima Mehmood Malhi, Huma Jawed, Nadeem Ashraf, Farina Hanif, Bina S. siddiqui, Farhat Zubair. “Modulation of C-FOS and BDNF Protein Expression In Pentylenetetrazole-Kindled Mice Following Treatment With Novel Antiepileptic Compound HHL-6.” Patent No: US 9,272,998 B1. March 2016

Research Grants

HEC SRGP Research grant as PI (2017-2018)

Received research grant of worth 0.5 Million PKR under Startup Research Grant program of Higher Education commission Pakistan for the project entitled “Anticancer Effect of compounds from Medicinal Plants Versus Standard Drug Temozolomide on Drug Resistant Glioblastoma cells” Projec # SRGP 1236.

Academic Honors and Awards

Travel Awards:

Won travel grant from IBRO to attend IBRO APRC Advance School of Neuroscience and present my research work at Tehran, Iran. April 29 to May 11, 2017

Junior Investigator travel award from International Society for Neurochemistry

(ISN) and Asia Pacific Society for Neurochemistry(APSN) to attend and present my research work in 14th Meeting of Asian-Pacific Society for Neurochemistry, Kuala Lumpur, Malaysia, Aug 27-30th 2016.

Student travel award from Safety Pharmacology Society (USA) to attend and present my research work in 13th Safety pharmacology society meeting at Rotterdam, Netherlands, Sep 15-20th 2013.

Won travel grant from Kuwait Institute of Scientific Research (KISR), TWAS and, OWSD to present my research work at International Conference on women in Science and technology in the Arab Countries at KISR, Kuwait. April 21 to 23 , 2013

Won travel grant from IBRO to attend IBRO School of Neuroscience at Selangor,

Malaysia. Nov 17 to 30 , 2012

Won travel grant from IBRO to attend IBRO School of Neuroscience and present my research work at Tehran, Iran. May 12 to 23, 2012

Winner of travel grant from IBRO to attend IBRO School of Neuroscience and present my research work at Beijing, China. Oct9-19th, 2011.

Scholarship:

Fully funded 6 months (Jan 2014-Jun 2014) scholarship was granted from Higher Education Commission, Pakistan, under the “International Research Support Initiative Program” to gain research training and experience at King’s College London, University of London.

Winner of Professor SM. Hamid Ali Scholarship from International Center for chemical and Biological sciences.2011-2014.

Oral Presentation: “The effects of morphine on activity of Lateral Paragigantocellularis (PGI)

Nucleus in Naïve and Morphine dependent Rats.” In IBRO APRC advance school of Neuroscience, Tehran Iran, April 29-May 11 2017

“N-(2- hydroxyl phenyl) acetamide potentiates temozolomide anticancer

efficacy by increasing active caspase-3 expression.” in 52nd Annual Medical Symposium held at Basic Medical Science Institute, Jinnah Postgraduate medical college Karachi, Pakistan, Jan, 17 2017

“In vitro Modulation of Human Glioblastoma Cells by N-(2-Hydoxy Phenyl)

Acetamide at Department of Biological and Biomedical Sciences, The Aga Khan University Karachi, Pakistan Jan, 2016.

“NA-2 inhibits Glioblastoma Cell proliferation by down-regulating VEGF expression”. In International Conference on Women in Science and Technology in the Arab countries, held in Kuwait, April 21-23, 2013

“The Effects Of Novel Antiproliferative Compound NA-2 In Combination, With Temozolomide On Human Glioblastoma Cells” in 3rd International NeuroMalaysia conference, Malaysia 2012.

won 1st prize for oral presentation at IBRO school of Neuroscience at Beijing, China. Oct 9-19th, 2011.

Poster Presentation:

Farina Hanif, Kahkashan Perveen, Shabana U Simjee , “N-(2- Hydroxyl Phenyl) acetamide potentiates temozolomide anticancer efficacy by increasing active caspase-3 expression” . Presented at 8th Annual Research Day, 2017 held at Dow University of Health Sciences, on Feb 25, 2017.

Farina Hanif, Kahkashan Perveen, Shabana U Simjee. “Verapamil potentiates temozolomide anticancer efficacy through the intrinsic apoptotic pathway in brain cancer cells”. Presented at 14th Meeting of Asian-Pacific Society for Neurochemistry, Kuala Lumpur, Malaysia, Aug 27-30th 2016. BEST POSTER AWARD.

Farina Hanif, Kahkashan Perveen, Saima Mahmood Malhi, Shabana U Simjee. “Calcium Channel Blocker Increases the Anticancer Activity of Temozolomide by Inhibiting Autocrine VEGF Signaling”. Presented at 15th Annual Meeting of Safety Pharmacology Society, Prague, Czech Republic, Sep 28th - 01st Oct 2015.

Farina Hanif, Bushra Chaudhry, Muneera Rasheed, Youseef Hussain, Naila Nadeem, and Bushra Afroze. “Association of CC2D1A deletion with Non-syndromic autosomal recessive mental retardation in Pakistani Population”. Presented at Health Science Research Assembly, Aga Khan University, Karachi, Pakistan, Aug22-23, 2016.

Farina Hanif, Bushra Chaudhry, Muneera Rasheed, Youseef Hussain, Naila Nadeem, and Bushra Afroze. “Association of TECR mutation with Non-syndromic autosomal recessive mental retardation in Pakistani Population”. Presented at Health Science Research Assembly, Aga Khan University, Karachi, Pakistan, Aug22-23, 2016.

Farina Hanif, Kausar Saboohi, Bushra Chaudhry. “Bioinformatics Navigation: Predicted Structure-Function Dynamics of Calpain10 Isoforms”. Presented at International Conference on Translational Medicine at Ziauddin University, Karachi, on 1-3 Feb 2016.

Farina Hanif, Kahkashan Perveen and Shabana Usman Simjee “Temozolomide and verapamil worked synergistically in human malignant glioblatoma cell line and increased apoptosis through activation of intrinsic pathway”

presented at 5th international symposium-cum-training course on Molecular Medicine and Drug Research” at PCMD, ICCBS, UoK on 12th-15th Jan 2015.

Kahkashan Perveen, Farina Hanif, and Shabana Usman Simjee “N-(2- hydroxy phenyl) acetamide controls toll-like receptors, TLR2 and TLR4 in experimental arthritis model ” presented at 5th international symposium-cum-training course on Molecular Medicine and Drug Research” at PCMD, ICCBS. 12-15 Jan 2015, organized by PCMD, ICCBS, UoK

Farina Hanif , Kahkashan Perveen and Shabana Usman Simjee. “Synergistic

effect of Verapamil and Temozolomide on growth inhibition of brain cancer

cells”, 1st Annual KCL Neuroscience symposium, London, United Kingdom. Mar

8th, 2014.

Farina Hanif , Kahkashan Perveen and Shabana Usman Simjee. “N-(2- hydroxy

phenyl) acetamide induces apoptosis of brain cancer cells by increasing

Bax/Bcl-2 ratio” presented at 13th Annual Safety Pharmacology Society

meeting, Rotterdam, Netherlands. Sep 15th-20th, 2013.

Kahkashan Perveen, Farina Hanif , and Shabana Usman Simjee. “Expressio n of

Toll-like receptors (TLR4) in splenocytes and its inhibition by N-2(-hydroxy

phenyl) acetamide in adjuant-indused arthritic rat model (AIA)” presented at

13th Annual Safety Pharmacology Society meeting, Rotterdam, Netherlands.

Sep 15th-20th, 2013.

Farina Hanif and Shabana Usman Simjee “The Effects Of Novel Antiproliferative Compound Na-2 In Combination, With Temozolomide On Human Glioblastoma Cells” presented at 4th international symposium on molecular Medicine and drug Research” at PCMD, ICCBS. 7-10 Jan 2013.

Farina Hanif; Saima Mehmood Malhi; Huma Jawed; Nadeem Ashraf; Farhat, Sabira Begum and Shabana. U. Simjee “HHL-6 down-regulates BDN expression in PTZ-induced kindling model of epilepsy in mice” presented at Neuroscience School organized by International Brain Research Organization (IBRO-APRC School Neurosciences) Tehran, Iran. May 12 to 23, 2012. (Ranked 2nd)

Farina Hanif; GK Siddiqui; Asif Rasheed; A.B. Maclean and PM Frossard “ VEGF gene dimorphism is a risk factor associated with Ovarian epithelial cancer in Pakistani women.” Presented at 3rd international symposium-cum-training course on molecular Medicine and drug Research at PCMD, ICCBS. 3-6 Jan 2011, organized by PCMD, ICCBS, UOK.

Saima Mehmood Malhi; Farina Hanif; Huma Jawed; Nadeem Ashraf; Farhat Sabira Begum and Shabana. U. Simjee “Effect of HH-L6, on kindling development and expression of BDNF and c-Fos in a model of epileptogenesis” Presented at 3rd international symposium-cum-training course on molecular Medicine and drug Research at PCMD, ICCBS. 3-6 Jan 2011, organized by PCMD,

ICCBS, UOK. ( 2nd Prize)

Farina Hanif Chhipa and Kaneez Fatima Shad, “Role of AMPA receptors in the onset and progression of Gliobastoma”, Presented at women in world Neuroscience symposium. 1st July 2010, organized by PCMD and Women in World Neuroscience.

Conferences and Workshops:

Workshops

Next Generation DNA Sequencing Data Analysis, at Jamil-ur-Rahman Center

for Genome Research, ICCBS, University of Karachi, Mar 27-29, 2017.

Multiple Choice Question (MCQs) Writing, at Dow Institute of Medical

Education (DIME), Dow University of Health Sciences (DUHS), Dec 20, 2016.

Basic Techniques in In Vitro Neural Differentiation from Stem Cells, University of Putra Malaysia, Selangor, Malaysia. Aug 22-26, 2016.

Training on Isolated Hear Perfusion Assembly, Department of Biological and Biomedical Sciences, Aga Khan University, May 17, 2016.

Fundamentals of Laboratory Safety, Department of Biological and Biomedical Sciences, Aga Khan University, Dec 21, 2015.

Techniques in Human Genomic studies, Jamil-ul-Rahman Center for genomics,

International Center for chemical and biological sciences, University of Karachi. 20-22 Aug 2014.

Workshop on Optogenetics, held at King’s College London, University of London, UK. 8- Mar 2014

Cell Culture Training Course, Mar 4-22, 2013, Conducted by Prof. Dr. Dieter Meyer (Germany) held at PCMD, International Center for Chemical and Biological Sciences, UOK.

IBRO School of Neurosciences, Organized by International Brain Research Organization on Nov 19 to 30, 2012 at Monash University, Jeffrey Cheah School of Medicine and Health Sciences, Malaysia

2nd Tehran IBRO School of Neurosciences, Molecular, Electrophysiological and Behavioral Approches, Organized by International Brain Research Organization on May 12 to 23, 2012 at Institute of Research in Fundamental Sciences (IPM) and Tarbiat Modares University, Tehran, Iran.

International Brain Research Organization (IBRO) APRC School of Neurosciences, 9-19 Oct, 2011, at Capital Medical University, Beijing, China.

How to write a winning scientific research proposal, Sep 24, 2011, Organized by L.E.J. National Sciences Information Center under Virtual Education Project Pakistan and Higher Education Commission Pakistan.

How to write scientific Manuscripts for High Impact factor Journals, July 23, 2011, organized by L.E.J. National Sciences Information Center under Virtual Education Project Pakistan and Higher Education Commission Pakistan.

Nation Wide Patch Clamp Workshop, Dec 21-23 2009, organized by PCMD, UOK.

Workshop on Biosafety, organized by The Aga Khan University.

Workshop on Introduction to Quantitative Data Analysis through SPSS Program, Aug 25-29 2008, organized by The Aga Khan University.

Workshop on Chemical Safety and Spill Management, The Aga Khan University

The Power of Projection, Jan 19 2009, Organized by The Aga Khan University

Conferences:

14th Meeting of Asian-Pacific Society for Neurochemistry held at Hotel Istana, Kuala Lumpur, Malaysia on Aug27th to 30th, 2016.

International Conference of Translational Medicine from Discovery to Health Care held at Ziauddin University, Karachi. Feb 1-3, 2016.

KCL Neuroscience symposium held at King’s College London, University of

London, UK. 8- Mar 2014.

13th Annual Meeting of the Safety Pharmacology Society, held at Convention Center, Rotterdam, Netherlands, Sep 16-19, 2013,

International Conference on Women in Science and Technology in the Arab Countries at KISR, Kuwait. April 21 to 23 , 2013

3rd International Neuromalaysia Symposium, Nov 29-30 2012, at Monash University Malaysia.

4th International Symposium-cum-Training Course on Molecular Medicine and Drug Research at PCMD, ICCBS. 7-10 Jan 2013, organized by PCMD, ICCBS, UOK

13th International Symposium on Natural Product Chemistry” 22- 25 Oct 2012 at HEJRIC, ICCBS. Organised by ICCBS, UOK.

1st International Conference on Building National Biosafety and Global Ties” 19th Nov 2011, Organised by Pakistan Biosafety Association.

“3rd International Symposium-cum-Training Course on Molecular Medicine and Drug Research” at PCMD, ICCBS. 3-6 Jan 2011, organized by PCMD, ICCBS, UOK.

12th International Symposium on Natural Product Chemistry, 22- 25 Nov 2010 at HEJRIC, ICCBS. Organised by ICCBS, UOK.

Development of Network of Women Neuroscientists in Pakistan, 1-2 july 2010. Organised by PCMD and Women in world neuroscience.

Think Science, Teaching Aid Competition, 2007 (2nd Prize)

CME: Parasitic Diseases: Improving Quality of Diagnosis to International Standards,

April 22, 2016. Aga Khan University

An Update on Endemic Parasitic Infections, Nov 24, 2016. Aga Khan University

Publications:

1. Hanif F, Muzaffar K, Perveen K, Malhi SM, Simjee ShU. (2017). Glioblastoma

Multiforme: A Review of its Epidemiology and Pathogenesis through Clinical

Presentation and Treatment. Asia Pacific journal of Cancer Prevention 18(1):3-9.

2. Bushra Chaudhry, Hanif F, Kausar Saboohi. (2017). Molecular Signatures of

Calpain 10 Isoforms Sequences, Envisage Functional Similarity and Therapeutic

Potential. (Accepted), Pakistan Journal of Pharmaceutical Sciences.

3. Hagiwara Y, Sieverling L, Hanif F, Anton J, Dickinson ER, Bui TT, Andreeva A,

Barran PE, Cota E and Nikolova PV. (2016). Consequences of point mutations in

melanoma-associated antigen 4 (MAGE-A4) protein in human cancers: Insights

from structural and biophysical studies. Scientific Reports (npg) 6:25182

4. Chaudhry B, Alia A, Mah-e-Nu M, Hanif F (2016). Serum 25-Hydroxy vitamin D

levels and Metabolic Health Status in Obese individuals in Pakistan. Surgery for

obesity and related diseases. 12 (7): S205. DOI:

http://dx.doi.org/10.1016/j.soard.2016.08.357

5. Hanif F, Perveen K and Simjee SU (2016). Verapamil potentiates temozolomide

anticancer efficacy through the intrinsic apoptotic pathway in brain cancer

cells. Front. Cell. Neurosci. Conference Abstract: 14th Meeting of the Asian-

Pacific Society for Neurochemistry. doi: 10.3389/conf.fncel.2016.36.00190

6. Hanif F, Perveen K, Jawed H, Ahmed A , Malhi SM, Jamall S and Simjee SU

(2014) N-(2-hydroxyphenyl) acetamide (NA-2) and Temozolomide synergistically

induce apoptosis in human glioblastoma cell line U87. Cancer Cell

International. 14(1): 133.

7. Hanif F, Perveen K andSimjee SU (2014)N-(2-hydroxy phenyl) acetamide induces

apoptosis of brain cancer cells by increasing Bax/Bcl-2 ratio.Journal of

Pharmacological and Toxicological Methods.70 (1): 321.

8. Perveen K, Hanif F, Jawed H, Jamall S and Simjee SU (2014) N-(2-hydroxy

phenyl) acetamide: a novel suppressor of Toll-like receptors (TLR-2 and TLR-4) in

adjuvant-induced arthritic rats. Molecular and Cellular Biochemistry. 394(1-2):

67-75.

9. Perveen K, Hanif Fand Simjee SU (2014) Expression of toll-like receptor (TLR4) in

splenocytes and its inhibition by N-(2-hydroxy phenyl) acetamide in adjuvant

induce arthritic rat model (AIA). Journal of Pharmacological and Toxicological

Methods.70 (1): 322.

10. Malhi SM, Jawed H, Hanif F, Ashraf N, Zubair F, Siddiqui BS, Begum S, Kabir N

and Simjee SU (2014) Modulation of c-Fos and BDNF protein expression in

pentylenetetrazole-kindled mice following the treatment with novel

antiepileptic compound HHL-6. Biomed Research International.2014: 876712

11. Jawed H, ShahSUA,Jamall S, Perveen K, Hanif F, and Simjee SU(2014) N-(2-

hydroxy phenyl) acetamide produces profound inhibition of c-Fos protein and

mRNA expression in the brain of adjuvant-induced arthritic rats. Molecular and

Cellular Biochemistry. 2014:387.

12. Hanif F, Perveen K, Jawed H, and Simjee SU (2013) In vitro growth inhibition of

u87 glioblastoma cells by N-(2- hydroxy phenyl) acetamide. International

Journal of Medicine and Pharmaceutical Sciences.3 (4): 69 - 78.

13. Perveen K, Hanif F, Jawed H, and Simjee SU (2013) Protective efficacy of N-(2-

hydroxyphenyl) acetamide against adjuvant -induced arthritis (AIA) in rats.

Biomed Research International.2013: 635143.

14. Danish Saleheen et al. (2009) The Pakistan Risk of Myocardial Infarction Study:

a bio resource for study of genetic and other determinants of myocardial

infarction in South Asia. European Journal of Epidemiology. 24(6):329-38

15. Siddiqui G, Hanif F, Anwar N, Rasheed A, Maclean AB, and Frossard PM (2017)

Population Based Case Control Study of a VEGF Gene Dimorphism and Ovarian

Cancer Risk among Pakistani Women. (submitted)

16. Hanif F, Perveen K, Malhi SM, Simjee SU (2017). Verapamil Increases the Anti-

glioblastoma efficacy of temozolomide by modulating apoptotic signaling

(Submitted)

Published Abstracts:

Farina Hanif, Bushra Chaudhry, Muneera Rasheed, Youseef Hussain, Naila Nadeem, and Bushra Afroze. “Association of CC2D1A deletion with Non-syndromic autosomal recessive mental retardation in Pakistani Population”.Presented at Health Science Research Assembly, Aga Khan University, Karachi, Pakistan, Aug22-23, 2016.

Farina Hanif, Bushra Chaudhry, Muneera Rasheed, Youseef Hussain, Naila Nadeem, and Bushra Afroze. “Association of TECR mutation with Non-syndromic autosomal recessive mental retardation in Pakistani Population”. at Health Science Research Assembly, Aga Khan University, Karachi, Pakistan, Aug22-23, 2016.

Farina Hanif Bushra Chaudhry, Kausar Saboohi. (2016). Bioinformatics

Navigation: Predicted Structure-Function Dynamics of Calpain10 Isoforms. Presented at International Conference on Translational Medicine at Ziauddin University, Karachi, on 1-3 Feb 2016.

Farina Hanif, Kahkashan Perveen, Saima Mahmood Malhi, Shabana U Simjee.

“Calcium Channel Blocker Increases the Anticancer Activity of Temozolomide

by Inhibiting Autocrine VEGF Signaling”. Presented at 15th Annual Meeting of

Safety Pharmacology Society, Prague, Czech Republic, Sep 28th - 01st Oct 2015.

Farina Hanif, Kahkashan Perveen and Shabana Usman Simjee. “Synergistic

effect of Verapamil and Temozolomide on growth inhibition of brain cancer

cells”, 1st Annual KCL Neuroscience symposium, London, United Kingdom.

March 8th, 2014.

Farina Hanif and Shabana Usman Simjee. “The Effects Of antiproliferative

Compound Na-2 In Combination With Temozolomide On Human

Glioblastoma Cells. 4th international symposium-cum-training course on

molecular Medicine and drug Research at PCMD, ICCBS. 3-6 Jan 2013,

organized by PCMD, ICCBS, UOK.

Farina Hanif; Saima Mehmood Malhi; Huma Javed; Nadeem Ashraf; Farhat;

Sabira Begum and Shabana. U. Simjee “HHL-6 down-regulates BDN expression

in PTZ-induced kindling model of epilepsy in mice” presented at Neuroscience

School organized by International Brain Research Organization (IBRO-APRC

School Neurosciences) Tehran, Iran. May 12 to 23, 2012.

Farina Hanif and Kaneez Fatima Shad, “Role of AMPA receptors in the onset

and progression of Glioblastoma”. In a symposium Development of Network of

Women Neuroscientists in Pakistan, 2010.

Saima Mehmood Malhi; Farina Hanif; Huma Javed; N Ashraf; Farhat Sabira

Begum and Shabana. U. Simjee “Effect of HH-L6, on kindling development and

expression of BDNF and c-Fos in a model of epileptogenesis”, 2011.

Farina Hanif; GK Siddiqui; Asif Rasheed; A.B. Maclean and PM Frossard “ VEGF

gene dimorphism is a risk factor associated with Ovarian epithelial cancer in

Pakistani women”, 2011.

REFERENCES Dr. Shabana Usman Simjee, PhD Associate Professor HEJ Research Institute of Chemistry University of Karachi, Karachi, Pakistan Email: shabana.simjee@iccs.edu Phone: +92-0213-482490 (ext) 150

Prof. Dr. Talat Mirza, PhD Professor Dean Research Ziauddin University, Karachi, Pakistan Email: drtalatmirza@gmail.com Phone: 0333 2184453

Dr. Penka Nikolova, PhD Professor Emeritus Department of Biochemistry, Institute of Pharmaceutical Sciences, King’College London, University of London, UK Email: penka.nikolova@kcl.ac.uk Phone: 0044 207-848-4276