Cystic Fibrosis

By: Jenna Mahoney and Jake Tuyls

Beginning Quiz

Famous people with cystic fibrosis

• Albert Einstien

• Bob Flanagan

• Alice Martineau

Symptoms

• More than 1,400 mutations• Salty skin• Constant infection of the lung area• Salty Skin• thickened mucus & phlegm• Wheezing & Coughing• Poor nutrient absorbtion (equals poor

growth)

Later Symptons

• Polyps

• Clubbing of the fingers

• Infertility

causes

• Two defective genes

• Inherited

• Both parents need to be carriers

• More than 1,400 mutations

How does it affect the lungs

• Protein CFTR-Cystic Fibrosis conductance Transmembrane Regulator

• Defective gene doesn’t do its job

• Clogs lungs with mucus

• Causes other infections

Percentage of infection

• A.) Both parents are CF carriers 25% chance unaffected, 50% chance unaffected carrier, 25% chance affected

• B.) One parent is a CF carrier and one parent has CF; 50% chance affected (CF), 50% chance unaffected carrier

• C.) One parent has CF and one is a noncarrier; 100% chance unaffected carrier

• D.) one parent is a carrier and one is a noncarrier; 50% chance unaffected (no CF, no carrier), 50% chance unaffected carrier.

Treatments

• Airway clearance techniques

• Mucus thinners

• Antibiotics

• Bronchodilators

• Special diet and vitamins

• Lung transplant

People Affected

• Most common are caucasians

• Affects all races

• About 30,000 children and adults are diagnosed

• 10 million Americans are Carriers

• one of every 3,500 live births

• 1,000 new diagnoseses each year

When it Appears

• Born with it

• Can show up and be diagnosed at any time

• 80% are age 3

• 10% are age 18

How is it diagnosed

• Sweat test- high chloride

• Genetic test- blood or cells tested.

• Newborn screening

• Nasal potential difference test

Life Expectancy

• Average 37 years

sourceshttp://www.cff.org/AboutCF/Faqs/#Is_there_a_cure_for_cystic_fibrosis?

http://www.cysticfibrosis.com/faqs.cfm

http://www.cysticfibrosismaleinfertility.com/Cystic_Fibrosis.html

http://children.webmd.com/tc/cystic-fibrosis-topic-overview

http://www.famouspeoplebiography411.com/Famous-people/Famous-People-With-Cystic-Fibrosis.html