databases in medical geology - cprm.gov.br

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Databases in Medical Geology An important geoscientific tool for medical geology

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Page 1: Databases in Medical Geology - cprm.gov.br

Databases in MedicalGeology

An important geoscientific tool for medical geology

Page 2: Databases in Medical Geology - cprm.gov.br

Soils

Water

Sediments

Vegetation

Mosses

Bedrock

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Copper content (mg kg-1) of soils inthe conterminous United States

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Chernobyl accident 1986

Baseline for radioactive and other pollutingelements missingMore than 120 databases existed10 different sample media13 different analytical metodsMany ess. elements not measuredImpossible to compile a homogenous datasetHarmonised geochemical database needed

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Globalgeochemicaldatabase

FOREGSGeochemicalbaselinemapping

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Globalreferencenetwork

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•Stream water (filtered and unfiltered)•Stream sediment (mineral sediment, <0.150 mm)•Residual soil, upper horizon (topsoil) 0 - 25 cm without thetop organic layer (<2 mm)•Residual soil, lower (C) horizon (subsoil); a 25 cm layerwithin a depth range of 50 cm - 200 cm (<2 mm)•Humus where present•Overbank sediment, upper horizon 0-25 cm (<0.150 mm,optional)•Overbank sediment, bottom layer (<0.150 mm, optional)•Floodplain sediment, upper horizon 0 - 25 cm (<2 mm)•Floodplain sediment, bottom layer (<2 mm, optional)

FOREGS FIELD MANUAL

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Natural element concentrations (especially strontium) of stream waters in thearea of sulphate bearing carbonate rocks in Central Russia are in such a highlevel that they probably cause health risks. More detailed study is needed.

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BARENTSECOGEOCHEMISTRY

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Cd / Se

Health effects?

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THEMOOSE

DISEASEIN

SWEDEN

?

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METAL CONTENTS IN MOOSEMETAL CONTENTS IN MOOSE1982-19921982-1992

Cu -50%Cu -50%Cr -80%Cr -80%

Fe -Fe -Zn -Zn -

Cd -30%Cd -30%Mo +24%Mo +24%

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LIMING IN ACIDIFIED AREAS OF SWEDEN

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Riskareas

forcattle,moose,deer etc

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DIABETES TYPE 1

”CONCLUSION It is concluded that this study for the firsttime provides evidence that a low groundwater content ofzinc, which may reflect long-term exposure through drinkingwater, is associated with later development of childhoodonset diabetes.”

KarolinskaInstitute

The NationalBoard ofHealth andWelfare

GeologicalSurvey ofSweden

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MORBUSGAUCHER

300 casesdysfunction in the lipidmetabolism in the body,an inherited chemicalmalformation.

Spleen and liverenlargenment

Splendid genealogy records in Sweden

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Environmental GeochemicalMonitoring Network

5000 cells

71 elements

Regional Geochemistry - NationalReconnaissance

Stream sed.

400 000 samples

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pilot area

Environmental Risk Assessment Map of the Slovak Republic

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MATERIALSGEOCHEMICAL DATA

&HEALTH INDICATORS

GEOCHEMICAL DATA• Data from GEOCHEMICAL ATLAS• New samples and new analyses in SGR Mts.

• Soils (A horizon, 816 samples)• Stream sediments (1 844 samples)• Groundwater (797 samples)• Surface water (754 samples)• Vegetables (13 samples)

Total contents, toxicity tests (acute and chronic), mobility andbioavailability (5-step extraction), valence of some metals (Sb3-5, As3-5,Crt-6), mainly toxic metal (Al, As, Cd, Cu, Cr6+, Hg, Pb, Sb) organicmacro and micro pollutants.

materials

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HEALTH INDICATORSMEDICAL AND DEMOGRAPHIC DATA• Data from national databases• Direct medical research in pilot area

Health indicators – selected and standardized according to WHOmethodology

• Data from state registers• Data validated by SHI• Data represent average values of 5-years period (1993-1997)

6 main basic groups of Health indicators are used Demographic data Data of reproductive health Total mortality

Cancer mortality Chronic lung diseases Cardiovascular diseases

In each of mentioned groups several separate groups (according to age and sex)and several individual diagnosis are evaluated.

materials

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EPIDEMIOLOGICAL – MEDICAL research(ZLATA IDKA vill.)

determination of As, Sb in biological materials of people

Hair – 71 respondents

Nails – 73 respondents

Urine – 116 respondents

Blood – 117 respondents

materials

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methods

HEALTH RISK• calculated for soils and groundwater

• from potential toxic elements: As, Sb, Cu, Cr, Pb, Zn, Be, Cd, Hg, Ba

• for each of 100 municipalities in SGR

• carcinogenic and chronic risk

• for adults (70 y) and children (12 y)

• the way of input of contaminants – ingestion

• reference dose, calculation ADD, CSF – according to US EPA, 1998

• calculation was realised by software Risk ASS, US EPA, 1998

• chronic and carcinogenic risk level – excess lifetime chronic and carcinogenic affections assessed according to US EPA

• calculations of Health risk are presented in numeric (for 100 municipalities) and map form

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Risk level map of carcinogenic affectionsfrom Arsenic - groundwater

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Risk level mapof chronic diseasesfrom potentially toxic elements(As, Ba, Cd, Cr, Cu, Hg, Pb, Sb, Se, Zn) -groundwater

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Risk level map of carcinogenic affectionsfrom Arsenic - soils

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Risk level map of chronic diseasesfrom potentially toxic elements(As, Ba, Cd, Cr, Cu, Hg, Pb, Sb, Se, Zn) -children, soils

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pilot area

Environmental Risk Assessment Map of the Slovak Republic

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Extensive databases in Canada,China, EU, USA etc

Conclusions:

Quality control?

Speciation?

Sample type?

Purpose?