CURRICULUM VITAE David L. Dunn, M.D., Ph.D.

OFFICE ADDRESS: 323 East Chestnut Street Louisville, KY 40202-1823

BIRTH: December 4, 1952 Pontiac, Michigan

EDUCATION: B.S. Zoology, 1973 University of Michigan Ann Arbor, Michigan

M.D. 1977 University of Michigan Medical School Ann Arbor, Michigan

Ph.D. Microbiology, 1985 University of Minnesota Graduate School Minneapolis, Minnesota

Medical Fellow (General Surgery), 1977-1985 Fellow in Transplantation and Transplantation Immunology, 1985-1986 Department of Surgery University of Minnesota Minneapolis, Minnesota

UNIVERSITY OF MINNESOTA ACADEMIC APPOINTMENTS: Assistant Professor of Surgery, 1986-1989 Associate Professor of Surgery with Tenure, 1989-1993 Professor of Surgery with Tenure, 1993-2005 Interim Chair, Department of Surgery, 1995 Jay Phillips Professor and Chairman of Surgery, 1996-2005 Associate Member, Graduate Faculty in Surgery, 1986-1989 Head, Division of Surgical Infectious Diseases, 1987-2005 Full Member, Graduate Faculty in Surgery, 1989-2005 Full Member, Biomedical Science Ph.D. Faculty, 1990-2005 Director of Graduate Studies, Department of Surgery, 1993-2005 Full Member, University of Minnesota Cancer Center, 1994-2005 Residency Program Director, Department of Surgery, 1995-2005 Chief, Division of General Surgery, 1995-2005

UNIVERSITY AT BUFFALO/SUNY ACADEMIC APPOINTMENTS: Vice President for Health Sciences, 2005-2011 Professor of Surgery, Microbiology and Immunology with Tenure, 2006-2011

UNIVERSITY of LOUISVILLE ACADEMIC APPOINTMENTS Executive Vice President for Health Affairs, 2011-date

Professor of Surgery, Microbiology and Immunology with Tenure, 2011-date

-2BOARD CERTIFICATION:

Diplomate, American Board of Surgery, 1986

Recertified, American Board of Surgery, 1994

Recertified, American Board of Surgery, 2005

FELLOWSHIP: Candidate, American College of Surgeons, 1978-1989

American College of Surgeons, 1989-date

ACADEMIC AWARDS: Regents-Alumni Scholarship, University of Michigan, 1971 B.S. Zoology with High Distinction, University of Michigan, 1973 Alpha Omega Alpha, University of Michigan Medical School, 1976 American College of Surgeons Schering Scholarship Award, 1983-1984 Phi Kappa Phi, University of Minnesota Graduate School, 1983 David Gaviser Surgical Research Award, Department of Surgery, University of Minnesota, 1985 American Society of Transplant Surgeons Sandoz Transplant Fellowship (first recipient), 1985-1987

OTHER AWARDS AND RECOGNITION: Life Member, Fellowship Leadership Society, American College of Surgeons, 2005

Regents Circle, Fellowship Leadership Society, American College of Surgeons, 2007

ACADEMIC SOCIETY MEMBERSHIP: Alpha Omega Alpha, 1976

Fellow, Infectious Diseases Society of America, 1994 Central Surgical Association, 1995

American Society of Microbiology, 1983 Phi Kappa Phi, 1983 Surgical Infection Society, 1984 Association for Academic Surgery, 1986 American Society of Transplant Surgeons, 1986 Society of University Surgeons, 1987 Minnesota Surgical Society, 1987 Surgical Biology Club I, 1988 American Association of Immunologists, 1989 International Endotoxin Society, 1989 The Halsted Society, 1990 The Transplantation Society, 1990 Society of Critical Care Medicine, 1990 American Surgical Association, 1991 St. Paul Surgical Society, Honorary Member, 1993 Shock Society, 1994

-3Society of Clinical Surgery, 1995 Society of Graduate Surgeons of the Los Angeles County/University of Southern California Medical

Center, Honorary Member, 1995 Association for Surgical Education, 1995 Society of Surgical Chairmen, 1996 Minneapolis Surgical Society, 1996 James IV Association of Surgeons, 1999 Minnesota Academy of Medicine, 2003

ACADEMIC SOCIETY OFFICES, COMMITTEES and APPOINTMENTS Membership Committee, Surgical Infection Society, 1985-1988 Program Committee, Surgical Infection Society, 1988-1991 Program Committee, Association for Academic Surgery, 1988, 1990-1991 Committee on Social and Legislative Issues, Society of University Surgeons, 1989-1991 Minnesota State Chairman, American College of Surgeons Commission on Cancer, Cancer Liaison

Program 1989-1995 Recorder, Surgical Infection Society, 1989-1991 Chairman, Program Committee, Surgical Infection Society, 1989-1991 Chairman, Scientific Studies Committee, American Society of Transplant Surgeons, 1989-1993 Professional Education Committee, Minnesota Division of the American Cancer Society, 1989-1990 Councilman, Association for Academic Surgery, 1989-1990 Ad hoc Committee on Biological Agents, Surgical Infection Society, 1991 Chairman, Fellowship Committee, Surgical Infection Society, 1991-1992 Secretary, Association for Academic Surgery, 1991-1993 Councilman-at-Large, Society of University Surgeons, 1992-1995 President-Elect, Surgical Infection Society, 1992 Committee for the Forum on Fundamental Surgical Problems, American College of Surgeons, 1992-

1998 Program Committee, The Halsted Society, 1993-1995 Councilor-at-Large, American Society of Transplant Surgeons, 1993-1996 President, Surgical Infection Society, 1993 Vice-President, Minnesota Chapter of the American College of Surgeons, 1993 President-Elect, Association for Academic Surgery, 1994 Pre- and Postoperative Care Committee, American College of Surgeons, 1993-1999 Newsletter Editor, Association for Academic Surgery, 1994 Newsletter Editor, Surgical Infection Society, 1994 President-Elect, Minnesota Chapter of the American College of Surgeons, 1994 President, Association for Academic Surgery, 1995 Chairman, Scholarship Committee, Society of University Surgeons, 1995 Chairman, Program Committee, The Halsted Society, 1995 President-Elect, Society of University Surgeons, 1995 President, Minnesota Chapter of the American College of Surgeons, 1995 President, Society of University Surgeons, 1996

-4Course Director, 7th Annual Fundamentals of Surgical Research Course, Association for Academic

Surgery, 1996 Scientific Program Committee, International Endotoxin Society, 1996-1998 Admissions Committee, Society of Clinical Surgery, 1996 Treasurer, Society of University Surgeons Foundation, 1997-2000 Membership Committee, American Surgical Association, 1998 Flance/Karl Awards Committee, American Surgical Association, 1999 Pre- and Postoperative Care Committee, American College of Surgeons, Senior Member, 1999-2003

President, Society of University Surgeons Foundation, 2000-2002 Board of Governors, American College of Surgeons, 2001-2004 Director, James IV Association of Surgeons, Inc., 2002-2005 Chairman, Flance-Karl Award Committee, American Surgical Association, 2003-2004 President-Elect, Minneapolis Surgical Society, 2005

INTRAMURAL COMMITTEES and APPOINTMENTS: University of Minnesota Medical School

Cancer Task Force, 1986-1996

Cancer Center

General Clinical Research Center:

Search Committee Membership

Chair, Search Committee

Clinical Oncology Task Force, 1986-1996

American Cancer Society Clinical Oncology Professor Selection Committee, 1989 Cancer Registry Biostatistics Committee, 1991 Facility Planning Committee, 1991-1992 Immunology Planning Committee, 1991-1992 Database Advisory Committee, 1994-1995

General Advisory Committee, 1986-1989 Scientific Advisory Committee, 1986-1989, 1998-2005

M.D./Ph.D. Program: Steering Committee, 1986-2005 Physician Scientist Subcommittee, 1989-1992 Biomedical Scientist Ph.D. Program Committee, 1989-2005

Program Development and Evaluation Task Force, 1991-1995 Dean's Scientific Seminar Committee, 1993-1995 Committee of Private Practice, 1994-1997 Medical Students and Residents Task Force, 1994-1995

Deans Task Force on Graduate Medical Education, 1995-1996

Deans Advisory Committee, 1996-2005

Dean of Medical School, 1996 Head, Family Practice, 1996 Clinical Cancer Program Director, 1996-1997

Head, Urologic Surgery, 1995-1996 Head, Pediatrics, 1997-1998 Head, Anesthesiology 2003-2005

Medical School Education Council, 2001-2005 Chair, Medical School Finance Task Force, 2003 Chair, Medical School Finance Committee, 2003-2005 Clinical Scholar Tenure Committee, 2004-2005 Diversity Task Force, 2004-2005

University of Minnesota Ad hoc Committee on Clinical Research Training and Graduate Degrees, 1991-1995

University Senate, 1992-1995; alternate, 1998-1999

-5University of Minnesota Hospital/Fairview University Medical Center

Antibiotic Subcommittee, Pharmacy and Therapeutics Committee, 1986-2005

Pharmacy and Therapeutics Committee ad hoc Subcommittee for Development of Criteria for Use of Antibody to Gram-

Perioperative Drug Therapy Subcommittee of the Pharmacy and Therapeutics Committee, 1993-1995 Emerging

Co-Medical Director, Transplant Services, 1997-2005 Co-Director, Transplant Partnership, 2000-2005 Co-Chair, Operating

Disaster Committee, 1986-1994 Infection Control Committee, 1986-2005 Co-director, Pancreaticobiliary Disease Center, 1986-2005 Emergency Department Committee, 1987-1989 Transplant Program Utilization Work Force, 1987-1994 Operating Rooms Resource Utilization Work Force, 1987-1995 Quality Assurance Steering Committee, 1988-1992 Quality Assurance Special Work Group, 1991-1992

negative Endotoxin (HA-1A), 1991-1992 Clinical Outcomes Task Force, 1992-1996 Clinical Outcomes Task Force Subcommittee on the Outcome of Solid Organ Transplantation, 1992-1996

Patient Care Delivery Systems and Processes Task Force, 1992-1995 Minimally Invasive Surgery Task Force, 1992-1996 Committee on Professional Credentialing and Staff Privileges, 1993-1996

Technology Task Force, 1993-1995 Operating Room Steering Committee, 1995-1997 Hospital Budget Committee, 1996-1997 Co-Chair, Operating Room Committee, 1997-1999 Co-Chief, Surgical Services, 1997-1999

Room Committee, 2001-2005 University of Minnesota Clinical Associates

Program Development Committee, 1993-1996 Professional Liability Task Force, 1995-1996 Board Member, 1995-1997 Executive Committee, 1995-1997

University of Minnesota Physicians, Inc. Board Member, 1997-2005 Chair, Governance Committee, 1997-2000 Chair, Patient Services Contracting Subcommittee, 1997-2000 Nominations and Bylaws Committee, 1997-2000 Surgery Clinical Service Unit Manager, 1997-2005 Executive Committee, 2000-2005 Committee on Committees, 2002-2005 Chair, Audit Committee, 2001-2005 Chair, Investment Committee, 2002-2005 Clinical Practice Committee, 2003-2005

University of Minnesota Department of Surgery Quality Assurance Officer, 1990-1995 Promotion and Tenure Committee, 1993-2005 Private Practice Subcommittee of the Advisory Council, 1993-1995 Residency Review Committee, 1993-2005 Administrative Head, White Surgery Service, 1994-1995 Faculty Advisory Council, 1994-2005 Development Committee, 1995 Ad hoc Committee for Evaluation of the Residency Program, 1994-1995 Managing Partner, Department of Surgery Associates, 1995-2000

University at Buffalo/SUNY Executive Technology Advisory Group Faculty Recognition Committee Institutional Policy and Compliance Advisory Group Search Committee Membership

Dean, School of Engineering and Applied Sciences, 2006 Vice President, Development and Alumni Relations, 2006

-6Senior Leadership Strategy Committee Co-Chair, South Campus Academic Unit Space Needs Work Group Space Management & Facilities Planning Committee Executive Committee, Student Systems Assessment Acting Director, NYS Center of Excellence in Bioinformatics and Life Sciences Planning Board

University at Buffalo Associates, Inc. President and Chief Executive Officer, 2005-date

UB|MD Executive Committee and Management Committee Member, 2005-date

Buffalo 2020 Development Corporation President, 2009-2011

University of Louisville Chair, Health Sciences Center Compliance Committee Member, UofL Compliance Oversight Council Chair, UofL Veterans Administration Task Group

University of Louisville Foundation Member, University of Louisville Research Foundation Board of Directors

University of Louisville Hospital (University Medical Center) Member, University Medical Center, Inc. Board of Directors Member, University Medical Center, Inc. Finance, Audit and Compliance Committee Member, University Hospital Medical Executive Committee Member, University Medical Center Strategy Committee

University of Louisville Physicians Member, University of Louisville Physicians Board of Directors and Executive Committee Member, University Physician Associates Board of Directors and Executive Committee

EXTRAMURAL COMMITTEES, POSITIONS and BOARDS: Cancer Liaison Physician, American College of Surgeons Cancer Liaison Program, 1988-1994 Lifesource Advisory Board, 1989-1995 General Surgery Subcomittee of the Medica Medical Policy Council, 1993-1998 Kimberly Clark Advisory Board, 1993-1997 Chair, Bayer Surgery Advisory Board, 1994-1998 Fugisawa Surgery Advisory Board, 1994-2001 Rhone-Poulenc-Rohrer Advisory Board, 1995-2001 Zeneca Council of Surgical Consultants, 1997-2001 Chair, Western New York Regional Advisory Committee, New York State Commission on Health

Care Facilities in the 21st Century, 2005-2006 Buffalo Niagara Medical Campus, 2005-2011 HealtheLink, 2006-2011 Secretary/Treasurer, Great Lakes Health System, 2007-2011 Hauptman-Woodward Medical Research Institute, 2010-2011 Chair, Quality and Charity Care Trust Board of Directors Member, Nucleus Advisory Board of Directors Member, Passport Health Plan Board of Directors Member, Subscribers Advisory Committee (Kentuckiana Medical Reciprocal Risk Retention Group) Treasurer, Cardiovascular Innovation Institute Board of Directors, 2011-12 Chair, Cardiovascular Innovation Institute Board of Directors, 2012-2013 President and Chief Executive Officer, Health DataStream, 2012-date

-7EDITORIAL BOARDS:

Clinical Transplantation, 1989-2006 Critical Care Medicine, 1990-2008 Journal of Surgical Research, 1991-2000 Annals of Surgery, 1991-date Transplantation Science, 1991-1997 Medical Intelligence Unit, 1991-1997 Circulatory Shock, 1993-1997 Surgical Infections: Index & Reviews, 1993-1997 Transplantation, 1993-2011 Associate Editor, SHOCK: Molecular, Cellular, Systemic Pathobiological Aspects and Therapeutic

Approaches, 1993-2001 Sepsis, 1996-2000 Surgical Infections, 1998-date Journal of Investigative Surgery, 2001-date

EXTRAMURAL REVIEW COMMITTEES: Member, National Institutes of Health: Surgery, Anesthesiology and Trauma Study Section, Division of

Research Grants, 1993-1997 Reviewer, National Institutes of Health: Special Emphasis Panel ZGM1TB-2 (GG), Office of Scientific

Review, 2002

EXTRAMURAL GRANT SUPPORT: Previously Funded Projects National Institutes of Health National Research Service Award Pathogenic Factors in Experimental

Peritonitis. AM 0635301 (1981-1983). National Institutes of Health Young Investigator's Research Award Mechanisms of

Immunotherapeutic Protection during Gram-negative Bacterial Sepsis. R29 GM32414 (Principal Investigator, 1983-1986).

National Institutes of Health Public Health Service Grant Pathogenesis and Treatment of Experimental Peritonitis. R01 AI 14032 (Co-investigator, 1985-1988; Principal Investigator: Richard L. Simmons, M.D.).

National Institutes of Health Public Health Service Grant Translocating Bacteria: Role in Postsurgical Sepsis R01 AI 23484 (Co-investigator, 1986-1995; Principal Investigator: Carol L. Wells, Ph.D., Direct Costs = $101,877.00 per year).

National Institutes of Health P ublic Health Service Program Project Grant Studies of Organ Transplantation in Animals and Man P01 DK13083 (Co-investigator, 1987-1992; Program Director: John S. Najarian, M.D., Direct Costs = $830,332.00 per year).

Clinical Project IA (Co-investigator): Comparative effect of OKT3 and ALG for prophylactic immunosuppression in clinical renal transplantation: a prospective randomized study.

Clinical Project IE (Co-investigator): Continuing retrospective, prospective, and pilot studies in renal transplantation.

Clinical Project IIA (Co-investigator): Cytomegalovirus infections in transplant recipients. National Institutes of Health Research Career Development Award Mechanisms of immunotherapeutic

protection during gram-negative bacterial sepsis GM 00517 (Principal Investigator, 1988-1993, Direct Costs = $65,375.00 per year).

http:65,375.00http:830,332.00http:101,877.00

-8National Institutes of Health Public Health Service Postdoctoral Training Grant Research training for

surgical scientists T32 DK07566 (Co-investigator, 1988-1993; Principal Investigator: John S. Najarian, M.D., Direct Costs = $168,675.00 per year).

National Cancer Institute Public Health Service Program Project Grant Cancer and leukemia group B: Minnesota oncology group P01 CA16450 (Co-investigator, 1988-1993; Principal Investigator: Bruce A. Peterson, M.D., Direct Costs = $159,084.00 per year).

Minnesota Medical Foundation Research Grant Detection of rejection and graft versus host disease after rat small bowel and multivisceral organ transplantation (Principal Investigator, 1990-1991, Direct Costs = $10,000.00).

National Institutes of Health Public Health Service Program Project Grant Studies of organ transplantation in animals and man P01 DK13083 (Co-investigator, 1992-1997; Program Director: John S. Najarian, M.D., Direct Costs = $716,278 per year).

Clinical Project IIa (Principal Investigator): Prophylaxis, treatment, and pathogenesis of cytomegalovirus disease in solid organ transplant recipients.

Care-Tech Laboratories Grant Clinical Trial to Reduce Wound Infection Rates in Pancreas Transplant Recipients and Compare Techni-Care to Conventional Wound Care in the Treatment of Open Wounds (Principal Investigator, 1996-1998, Direct Costs = $60,000).

Roche Laboratories Grant Randomized, prospective trial of IV ganciclovir plus either oral ganciclovir or oral acyclovir in the prevention and treatment of CMV disease in recipients of solid organ allografts (Principal Investigator, 1996-2001, Direct Costs = $173,394).

National Institutes of Health Public Health Service Grant Mechanisms of Immunotherapeutic Protection during Gram-negative Bacterial Sepsis R01 GM32414 (Principal Investigator, 1986-2003, Direct Costs = $368,481 per year).

New York State Department of Health Award Management of End Stage Renal Disease in a Patient Centered Medical Home Model (Principal Investigator, 2009-date, Direct Costs = $7M).

TRAINEES AND ADVISEES: Advanced Admission Mentor Program

Kirsten R. Martinson 1989-1990 Undergraduate Honor Students

Christopher M. Schoonover 1989-1990 Rania A. Habib 2003-2004

Undergraduate Summer Research Students Donnette K. Morris 1991

Medical Students (Clinical Advisor) Kevin R. Miller, B.S. 1987-1988 Stephen T. Erickson, B.S. 1987-1988 Todd A. Kellogg, B.S. 1991-1992 Karla M. Kurrelmeyer, B.S. 1992-1993 Mark T. Eginton, B.S. 1994-1995 Christopher J. Hansen, B.S. 1995-1996 Donavon J. Hess, B.S. 1995-1996 Brent Nykamp, B.A. 2002-2003

Medical Students (Laboratory) Cyril J. Schweich, B.S. 1988 Dat T. Nguyen, B.S. 1989 Nancy E. Brass, B.S. 1989 Michael Momont, B.S. 1991 Todd A. Kellogg, B.S. 1992 Mark T. Eginton, B.S. 1994 Christopher D. Leville, B.A. 1995 Cassie Carlone Jambor, B.S. 1996 Vadim Pisarenko, B.S. 2000

http:10,000.00http:159,084.00http:168,675.00

-9Martin D. Zielinski, B.S. 2002 Hoai D. Pham, B.S. 2002 David R. Eng, B.A. 2004

Medical Fellows (Surgical Infectious Diseases) Ginny L. Bumgardner, M.D. 1987-1988 Carlos G. Fasola, M.D. 1988-1989 Richard J. Fischel, M.D. 1988-1989 Russell A. Shatford, M.D. 1988-1989 Jaime L. Mayoral, M.D. 1988-1990 Cynthia M. Loeffler, M.D. 1989-1990 Alan C. Farney, M.D. 1990-1991 Edic Stephanian, M.D. 1990-1991 Carolyn S. Cody, M.D. 1990-1992 Mark D. Sawyer, M.D. 1990-1992 Randall S. Burd, M.D. 1990-1993 Darla K. Granger, M.D. 1991-1993 Mitchell S. Farber, M.D. 1991-1994 Sung K. Kim, M.D. 1991-1994 Richard J. Battafarano, M.D. 1991-1995 David C. Wahoff, M.D. 1992-1994 Jeffrey E. Everett, M.D. 1992-1995 Timothy D. Sielaff, M.D. 1992-1995 Peter S. Dahlberg, M.D. 1993-1996 Daniel A. Saltzman, M.D. 1993-1996 Karen J. Brasel, M.D. 1994-1996 Paul H. Bloch, M.D. 1994-1996 Robert D. Acton, M.D. 1994-1997 Marc E. Uknis, M.D. 1994-1997 Karol A. Gutowski, M.D. 1995-1997 Eric M. Johnson, M.D. 1995-1997 Stephen R. Kerr, M.D. 1995-1997 Christopher T. Salerno, M.D 1995-1998 Jeffrey W. Kronson, M.D. 1996-1997 Stanley V. DeTurris, M.D. 1996-1998 Renae E. Stafford, M.D. 1996-1998 Charles A. Svendsen, M.D. 1996-1998 Todd A. Kellogg, M.D. 1996-1999 Carl A. Weiss,III, M.D. 1996-1999 James V. Harmon, M.D. 1997-1998 John W. Cromwell, M.D. 1997-1999 Sharon L. Dykes, M.D. 1997-1998 Benjamin D. Suhr, M.D. 1997-1999 Christine C. Toevs, M.D. 1997-1999 Brad A. Feltis, M.D. 1998-2001 John F. Grehan, M.D. 1998-2002 Victor Lazaron, M.D., Ph.D. 1998-2002 Brian C. Grubbs, M.D. 1998-2001 Bradley C. Linden, M.D. 1999-2003 Donovan J. Hess, M.D. 1999-2003 Peter V. Ching, M.D. 2000-2003 Jonathan D Cunha, M.D. 2000-2003 Kambi Kosari, M.D. 2000-2003 Daniel B. Leslie, M.D. 2000-2003 Karen E. Hodgson, M.D. 2001-2002 Robert P. Gallegos, M.D. 2001-2004 Chuong D. Hoang, M.D. 2001-2004 Kaysie L. Banton, M.D. 2003-2005

Medical Fellows (Basic Research) Brian P. Priest, M.D. 1986-1988 Jaime L. Mayoral, M.D. 1988-1991

-10W. Graham Williams, B.Sc., M.Ch. 1989-1990 Carlos G. Fasola, M.D. 1989-1990 Jacques Pirenne, M.D. 1989-1990 Carolyn S. Cody, M.D. 1990-1992 Mark D. Sawyer, M.D. 1990-1992 Randall S. Burd, M.D. 1990-1993 Sung K. Kim, M.D. 1991-1994 Richard J. Battafarano, M.D. 1991-1995 Mitchell S. Farber, M.D. 1992-1994 Peter S. Dahlberg, M.D. 1993-1996 Robert D. Acton, M.D. 1994-1997 Hans G. Klaerner, M.D. 1994-1997 Marc E. Uknis, M.D. 1994-1997 Todd A. Kellogg, M.D. 1996-1999 Carl A. Weiss, III, M.D. 1996-1999 Christine C. Toevs, M.D. 1997-1999 Victor Lazaron, M.D., Ph.D. 1998-2001 Daniel B. Leslie, M.D. 2000-2004 Paul S. Vietzen, M.D. 2001-2004 Kaysie L.Banton, M.D. 2004-2005

M.S. Candidates Jacques Pirenne, M.D. (M.S. Experiental Surgery) 1990

Thesis Research Advisor and Committee Chair Rebecca Ann Redepenning Diekmann (M.S. Nursing) 1994

Thesis Reviewer and Committee Member Ph.D. Candidates

Michael A. West, M.D. (Ph.D. Surgery) 1988 Thesis Reviewer and Committee Member

Randall S. Burd, M.D. (Ph.D. Surgery) 1994 Thesis Research Advisor

Dixon Kaufman, M.D. (Ph.D. Surgery) 1995 Thesis Committee Chair

Richard J. Battafarano, M.D. (Ph.D. Biomedical Sciences) 1997 Thesis Research Advisor

Jeffrey E. Everett, M.D. (Ph.D. Surgery) 1997 Thesis Research Advisor David C. Wahoff, M.D. (Ph.D. Surgery) 1997

Thesis Research Advisor Peter S. Dahlberg, M.D. (Ph.D. Surgery) 1997

Thesis Research Advisor Carl A. Weiss, III, M.D. (Ph.D. Surgery) 2000

Thesis Research Advisor Fellow Awards

Jaime L. Mayoral, M.D. 10th Annual Meeting of the Surgical Infection Society, Best Poster 1990

Carolyn S. Cody, M.D. Surgical Infection Society, Stuart Pharmaceuticals Fellow 1990-1992

Randall S. Burd, M.D. 11th Annual Meeting of the Surgical Infection Society, Resident Award 1991

Randall S. Burd, M.D. 25th Annual Meeting of the Association for Academic Surgery, Resident Research Award 1991

Randall S. Burd, M.D. NIH/PHS National Research Service Award Immunotherapy of Neonatal

Gram-Negative Bacterial Peritonitis, GM14344 1991-1994 Richard J. Battafarano, M.D.

Association for Academic Surgery Davis & Geck Surgical Research Award 1992-1994 Randall S. Burd, M.D.

David Gaviser Surgical Research Award, Department of Surgery, University of Minnesota 1994

-11Peter S. Dahlberg, M.D.

American College of Surgeons Merck Scholarship for the Study of Surgical Infection 1994-1996

Richard J. Battafarano, M.D. David Gaviser Surgical Research Award, Department of Surgery,

Carl A. Weiss, III, M.D.

Carl A. Weiss, III, M.D. NIH/PHS National Research Service Award Characterization of BPI-derived

Todd A. Kellogg, M.D. NIH/PHS National Research Service Award Anti-idiotypic Antibodies as

Victor Lazaron, M.D., Ph.D. NIH/PHS National Research Service Award LBP-BPI-Based Endotoxin

Daniel B. Leslie, M.D. Society of University Surgeons-Ethicon Fellowship Award Native Limulus Anti-lipopolysaccharide Factor (LALF)-

Paul S. Vietzen, M.D. Surgical Infection SocietyFellowship Award Bio logical Basis of Endotoxin

University of Minnesota 1995 Peter S. Dahlberg, M.D.

16th Annual Meeting of the Surgical Infection Society, Resident Award 1996

Surgical Infection Society, Marion Merrell Dow Fellow 1996-1997

Endotoxin Antagonists, GM18835 1997-1999

Endotoxin Antagonists, GM19030 1997-1999

Antagonists 1999-2001

based Endotoxin Antagonist 2001-2003

Antagonism by LALF 2003-2004

-12BIBLIOGRAPHY

Published Manuscripts *1.Dunn DL, Simmons RL. The mechanism of bacterial trapping by polymerizing fibrin. Surg Forum

32:42- 4, 1981. *2.Dunn DL, Ferguson R. Immunotherapy of gram-negative bacterial sepsis: enhanced survival in a

guinea pig model by use of rabbit antiserum to Escherichia coli J-5. Surgery 92:212-9, 1982. *3.Dunn DL, Simmons RL. Fibrin in peritonitis. III. The mechanism of bacterial trapping by polymerizing

fibrin. Surgery 92:513-9, 1982. *4.Dunn DL, Barke RA, Condie RM, Humphrey EW, Simmons RL. The effect of stroma-free

hemoglobin on clearance of bacteria from the peritoneal cavity. Surg Forum 33:28-30, 1982. 5.Dunn DL, Simmons RL. Enlarged lymph glands and fear of Hodgkin's disease. Collected letters in

Surgery. The Correspondence Society of Surgeons 5:2-3, 1982. *6.Dunn DL, Nelson RD, Condie RM, Simmons RL. Mechanisms of the adjuvant effect of hemoglobin in

experimental peritonitis. VI. Effects of stroma-free hemoglobin and red blood cell stroma on mortality and neutrophil function. Surgery 93:653-9, 1983.

*7.Dunn DL, Simmons RL. The meaning of research in experimental peritonitis. Surgery 93:471-4, 1983. *8.Dunn DL, Barke RA, Lee JT Jr, Condie RM, Humphrey EW, Simmons RL. Mechanisms of the adjuvant

effect of hemoglobin in experimental peritonitis. VII. Hemoglobin does not inhibit clearance of Escherichia coli from the peritoneal cavity. Surgery 94:487-93, 1983.

*9.Dunn DL, Simmons RL. Rational empiric antibiotic therapy of peritonitis and intraabdominal infection. Infect Surg 2:466-83, 1983.

*10.Dunn DL, Mach PA, Cerra FB, Ferguson RM. The role of heparin in guinea pig gram-negative bacterial sepsis. J Surg Res 34:479-85, 1983.

*11.Dunn DL, Mach PA, Cerra FB. Monoclonal antibodies protect against lethal effects of gram-negative bacterial sepsis. Surg Forum 34:142-4, 1983.

*12.Barke RA, Dunn DL, Dalmasso AP, Orser M, Simmons RL, Humphrey EW. The effect of Ibuprofen treatment versus Ibuprofen pretreatment on pulmonary microvascular permeability and pulmonary function following E. coli peritoneal contamination. Surg Forum 34:144-6, 1983.

*13.Dunn DL, Simmons RL. The role of anaerobic bacteria in intraabdominal infections. Rev Infect Dis 6:S139-46, 1984.

*14.Barke RA, Dunn DL, Johnson J, Dalmasso A, Orser M, Simmons RL, Humphrey EW. The pulmonary effects of live vs. dead E. coli peritonitis. Arch Surg 119:173-9, 1984.

*15.Dunn DL, Rotstein OD, Simmons RL. Fibrin in peritonitis. IV. Synergistic intraperitoneal infection due to Escherichia coli and Bacteroides fragilis within fibrin clots. Arch Surg 119:134-44, 1984.

*16.Dunn DL, Barke RA, Ahrenholz DA, Humphrey EW, Simmons RL. The adjuvant effect of peritonea fluid in experimental peritonitis: mechanism and clinical implications. Ann Surg 199:37-43, 1984.

17.Dunn DL, Simmons RL. Peculiar behavior of an appendectomy wound. Collected letters in Surgery. The Correspondence Society of Surgeons 7:6-8, 1984.

*18.Dunn DL, Mach PA, Condie RM, Cerra FB. Anti-core endotoxin F(ab')2 equine immunoglobulin fragments protect against lethal effects of gram-negative bacterial sepsis. Surgery 96:440-6, 1984.

*19.Dunn DL, Matas AJ, Fryd DS, Simmons RL, Najarian JS. Association of concurrent herpes simplex virus and cytomegalovirus with detrimental effects afters renal transplantation. Arch Surg 119:812-7, 1984.

*20.Dunn DL, Barke RA, Lee JT, Jr, Simmons RL. Use of a bacterial mutant to study the adjuvant effect of hemoglobin in experimental Escherichia coli peritonitis. Surg Forum 35:132-4, 1984.

-13*21.Dunn DL, Bogard WC, Cerra FB. Enhanced survival during murine gram-negative bacterial sepsis by

use of a murine monoclonal antibody. Arch Surg 120:50-3, 1985. *22.Dunn DL, Mach PA, Dalmasso AP, Ferguson RM, Cerra FB. Metabolic effects of pretreatment with

Escherichia coli J5 antiserum on guinea pig gram-negative bacterial sepsis. J Surg Res 38:298-304, 1985.

*23.Dunn DL, Barke RA, Ewald DC, Simmons RL. Effects of Escherichia coli and Bacteroides fragilis on peritoneal host defenses. Infect Immun 48:287-9 1, 1985.

*24.Dunn DL, Bogard WC, Cerra FB. Efficacy of type specific and cross reactive murine monoclonal antibodies directed against endotoxin during experimental sepsis. Surgery 98:283-90, 1985.

*25.Dunn DL, Barke RA, Knight NB, Humphrey EW, Simmons RL. Role of resident macrophages, peripheral neutrophils, and translymphatic absorption in bacterial clearance from the peritoneal cavity. Infect Immun 49:257-64, 1985.

*26.Dunn DL, Ewald DP, Chandan N, Cerra FB. Immunotherapy of gram-negative bacterial sepsis: a single murine monoclonal antibody provides cross-genera protection. Arch Surg 121:58-62, 1986.

*27.Bogard WC, Dunn DL, Abernethy K, Kilgarriff, C, Kung PC. Isolation and characterization of murine monoclonal antibodies specific for gram-negative bacterial lipopolysaccharide: association of cross-genus reactivity with lipid A specificity. Infect Immun 55:899-908, 1987.

*28.Dunn DL, Barke RA, Ewald DC, Simmons RL. Macrophages and translymphatic absorption represent the first line of host defense of the peritoneal cavity. Arch Surg 122:105-10, 1987.

*29.Dunn DL. Immunotherapeutic advances in the treatment of gram-negative bacterial sepsis. World J Surg 11:233-40, 1987.

*30.Dunn DL. Vaccines and antibody immunotherapy in surgical patients. Am J Surg 153:409-16, 1987. *31.Dunn DL. Antibody immunotherapy of gram-negative bacterial sepsis. Pharmacotherapy 7:S3 1-5, 1987. *32.Stock PG, Snover D, Payne W, Dunn DL, Simmons RL, Najarian JS, Ascher NL. Biopsy guided

immunosuppressive therapy in treatment of liver transplant rejection: an individualized approach. Clin Transplantation 1:179-86, 1987.

33.Dunn DL. Management of recurrent retroperitoneal liposarcoma. Collected letters in Surgery. The Correspondence Society of Surgeons, 10:2-4, 1987.

34.Dunn DL, Simmons RL. Management of unsuspected carcinoma of the appendix. Collected letters in Surgery. The Correspondence Society of Surgeons, 10:7-8, 1987.

*35.Dunn DL. Antibody immunotherapy of gram-negative bacterial sepsis in an immunosuppressed animal model. Transplantation 45:424-9, 1988.

*36.Billiar TR, Maddaus MA, West MA, Dunn DL, Simmons RL. The role of intestinal flora on the i nte r a c t i ons be tw e e n non -p ar en ch y m al cel l s an d h epat o cy t es i n co cu l t u r e. J Su r g Res 44:397-403, 1988.

37.Gruber SA, Simmons RL, Vercellotti G, Najarian JS, Ascher NL, Dunn DL, Payne WD, Sutherland DER, Fryd DS. Erythrocytosis and thromboembolic complications after renal transplantation: results from a randomized trial of cyclosporine versus azathioprine-antilymphocyte globulin. Transplant Proc 20(S3):948-50, 1988.

*38.Chan GL, Canafax DM, Ascher NL, Dunn DL, Payne WD, Fryd DS, Noreen H, Sutherland DER, Simmons RL, Najarian JS. HLA-identical sibling renal transplants: no rejections with a cyclosporine-azathioprine-prednisone protocol. Clin Transplantation 2:9-14, 1988.

*39.Gruber SA, Simmons RL, Najarian JS, Vercellotti G, Ascher NL, Dunn DL, Payne WD, Sutherland DER, Fryd DS. Posttransplant erythrocytosis and the risk of thromboembolic complications: correlation from a prospective randomized study of cyclosporine versus azathioprine-antilymphocyte globulin. Clin Transplantation 2:60-6, 1988.

-1440.Roberts JP, Fryd DS, Ascher NL, Migliori R, Payne WD, Dunn DL, Sutherland DER, Simmons RL,

Najarian JS. Living related kidneys continue to provide superior results over cadaveric kidneys in the cyclosporine era. Transplant Proc 20, S 1:26-7, 1988.

41.Najarian JS, Migliori RJ, Simmons FL, Ascher NL, Payne WD, Dunn DL, Sutherland DER, Fryd DS. Effects of HLA matching in cadaver renal transplants. Transplant Proc 20, S3:249-56, 1988.

42.Ford HR, Fryd DS, Canafax DM, Ascher NL, Dunn DL, Sutherland DER, Najarian JS, Simmons RL. Adjunctive azathioprine and antilymphocyte serum immunosuppressive with cyclosporine. Transplant Proc 20, S3:8-12, 1988.

*43.Sutherland DER, Kendall DM, Moudry KC, Navarro X, Kennedy WR, Ramsay RC, Steffes MW, Mauer SM, Goetz FC, Dunn DL, Najarian JS. Pancreas transplantation in nonuremic, type I diabetic recipients. Surgery 104:453-64, 1988.

*44.Priest BP, Bankey PE, Cerra FB, Dunn DL. An immunoprotective antibody directed against lipopolysaccharide inhibits tumor necrosis factor production in vitro. Surg Forum 39:29-30, 1988.

*45.Dunn DL, Priest BP, Condie RM. Protective capacity of polyclonal and monoclonal antibodies directed against endotoxin during experimental sepsis. Arch Surg 123:1389-93, 1988.

46.Dunn DL. Use of antibiotics in the treatment of minor wounds. Collected letters in Surgery. The Correspondence Society of Surgeons 11:4-5, 1988.

*47.Billiar TR, West MA, Hyland BJ, Cerra FB, Simmons RL, Dunn DL. Murine monoclonal antibody directed against lipopolysaccharide (LPS) inhibits Kupffer cell activation by endotoxin in vitro. Prog Clin Biol Res 264:367-72, 1988.

*48.Fischel RJ, Freise CE, Bonser RS, Hertz MI, Jamieson SW, Dunn DL. Successful management of fulminant cytomegalovirus induced acute lung injury following double lung transplantation. Clin Transplantation 2:33 1-5, 1988.

*49.Bumgardner GL, Payne WD, Dunn DL, Sutherland DER, Fryd DS, Mauer MS, Ascher NL, Simmons RL, Najarian JS. Single center 1-15 year results of renal transplantation in patients with systemic lupus erythematosus. Transplantation 46:703-9, 1988.

*50 .Sutherland DER, Moudry MC, Dunn DL, Goetz FC, Najarian JS. Pancreas transplant outcome in relation to presence or absence of end-stage renal disease, timing of transplant, surgical technique, and donor source. Diabetes 38(S1): 10-2, 1989.

*51.Barke RA, Dunn DL, Dalmasso AP, O'Connor-Allen M, Simmons RL, Humphrey EW. The association of E.coli virulence and pulmonary microvascular damage. Arch Surg 124:449-52, 1989.

52.Bumgardner GL, Mauer SM, Ascher NL, Payne W, Dunn DL, Fryd DS, Sutherland DER, Simmons RL, Najarian JS. Long-term outcome of renal transplantation in patients with systemic lupus erythematosus. Transplant Proc 21:2031-2, 1989.

*53.Dunn DL, Simmons RL. Opportunistic infections after renal transplant. I. Viral and bacterial infections. Infect Surg 8:164-75, 1989.

*54.Priest BP, Schlievert PM, Dunn DL. Treatment of toxic shock syndrome with endotoxin-neutralizing antibody. J Surg Res 46:527-3 1, 1989.

*55.Canafax DM, Min DI, Gruber SA, Fryd DS, Matas AJ, Payne WD, Dunn DL, Sutherland DER, Simmons RL, Najarian JS. Immunosuppression of cadaveric renal allograft recipients: a risk-factor matched comparison of the Minnesota randomized trial with an antilymphoblast globulin, azathioprine, cyclosporine, and prednisone protocol. Clin Transplantation 3:110-9, 1989.

*56.Pescovitz MD, Dunn DL, Sutherland DER. Use of the circular stapler in construction of the duodenoneocystostomy for drainage into the bladder in transplants involving the whole pancreas. Surgery, Gynecol Obstet 169:169-71, 1989.

*57.Dunn DL, Simmons RL. Opportunistic infections after renal transplant. II. Fungal and protozoan infections. Infect Surg 8:277-84, 1989.

-15*58.Priest BP, Brinson DN, Schroeder DA, Dunn DL. Treatment of experimental gram-negative

bacterial sepsis with murine monoclonal antibodies directed against lipopolysaccharide. Surgery 106:147-55, 1989.

*59.Gruessner RWG, Matas AJ, Lloveras G, Fryd DS, Dunn DL, Payne WD, Sutherland DER, Najarian JS. A comparison of single and double pediatric cadaver donor kidneys for transplantation. Clin Transplantation 3:209-14, 1989.

60.Sawyer MD, Dunn DL. Minimal medullary carcinoma of the breast-how much treatment is enough? Collected letters in Surgery. The Correspondence Society of Surgeons 12:3-4, 1989.

61.Matas AJ, Sutherland DER, Payne WD, Dunn DL, Perry E, Najarian JS. New approaches to living donor renal transplantation. Minnesota Med 72:589-92, 1989.

*62.Sutherland DER, Dunn DL, Goetz FC, Kennedy W, Ramsay RC, Steffes MW, Mauer SM, Gruessner R, Moudry-Munns KC, Morel P, Viste A, Robertson RP, Najarian JS. A ten year experience with 290 pancreas transplants at a single institution. Ann Surg 2 10:274-88, 1989.

*63.Roberts JP, Ascher NL, Fryd DS, Hunter DW, Dunn DL, Payne WD, Sutherland DER, Castaneda-Zuniga W, Najarian JS. Transplant renal artery stenosis. Transplantation 48:580-3, 1989.

*64.Tzardis PJ, Gruessner RWG, Matas AJ, Payne WD, Dunn DL, Sutherland DER, Najarian JS. Renal transplantation in patients with polycystic kidney disease: a single center experience. Clin Transplantation 3:325-30, 1989.

*65.Mayoral JM, Schweich CJ Jr, Dunn DL. Decreased tumor necrosis factor production during the initial stages of infection correlates with survival during murine gram-negative sepsis. Arch Surg 125:24-8, 1990.

*66.Dunn DL. Autochthonous microflora of the gastrointestinal tract. Perspect Colon Rectal Surg 2:105-19, 1990.

*67.Morel P, Moudry-Munns KC, Najarian JS, Gruessner RWG, Dunn DL, Sutherland DER. Influence of preservation time on outcome and metabolic function of bladder-drained pancreatic transplants. Transplantation 49:294-303, 1990.

68.Gruessner RWG, Matas AJ, Dunn DL, Lloveras G, Payne WD, Sutherland DER, Najarian JS. A comparison of pediatric versus adult cadaver donor kidneys for transplantation. Transplant Proc 22:361-2, 1990.

69.Dunn DL, Schlumpf RB, Gruessner RWG, Morel P, Mayoral JL, Payne WD, Matas AJ, Sutherland DER, Moudry-Munns KC, Najarian JS. Maximal use of liver and pancreas from cadaveric organ donors. Transplant Proc 22:423-4, 1990.

70.Gores PF, Viste A, Hesse U, Moudry-Munns KC, Dunn DL, Sutherland DER. The influence of donor hyperglycemia and other factors on long-term pancreatic allograft function. Transplant Proc 22:437-8, 1990.

71.Morel P, Moudry-Munns KC, Balakumar M, Najarian JS, Dunn DL, Sutherland DER. Influence of preservation time on the early function of pancreas transplants. Transplant Proc 22:527-8, 1990.

72.Gruessner RWG, Dunn DL, Tzardis PJ, Nakhleh RE, Najarian JS, Sutherland DER. Complications occurring after whole organ duodenopancreatic transplantation: relation to the allograft duodenal segment. Transplant Proc 22:578-9, 1990.

73.Morel P, Schlumpf RB, Moudry-Munns KC, Dunn DL, Sutherland DER. Pancreatic retransplants: an analysis of the outcome. Transplant Proc 22:620-1, 1990.

74.Gruessner RWG, Dunn DL, Tzardis PJ, Tomadze G, Moudry-Munns KC, Matas AJ, Najarian JS, Sutherland DER. Simultaneous pancreas and kidney transplants versus single kidney transplants and previous kidney transplants in uremic patients and single pancreas transplants in nonuremic diabetic patients: comparison of rejection, morbidity, and long-term outcome. Transplant Proc 22:622-3, 1990.

-1675.Burke GW III, Gruessner RWG, Dunn DL, Sutherland DER. Conversion of whole pancreaticoduodenal

transplants from bladder to enteric drainage for metabolic acidosis or dysuria. Transplant Proc 22:651-2, 1990.

76.Dunn DL, Gruessner RWG, Tzardis PJ, Nakhleh RE, Sutherland DER, Najarian JS. Pancreatic allograft loss secondary to periallograft gastrointestinal cytomegalovirus ulceration. Transplant Proc 22:678-9, 1990.

77.Kaufman DB, Platt JL, Rabe F, Dunn DL, Sutherland DER. Effect of host immunomodulation on the prevention of islet allograft primary nonfunction in a murine model. Transplant Proc 22:857-8, 1990.

78.Schlumpf R, Morel P, Sutherland D, Moudry-Munns K, Gruessner R, Payne W, Dunn D. Combined procurement of pancreas and liver grafts does not affect transplant outcome. Transplant Proc 22:2074-5, 1990.

*79.Tzardis PJ, Gruessner RWG, Matas AJ, Payne WD, Dunn DL, Sutherland DER, Najarian JS. Long-term f o l lo w -up of r e n a l t r a ns p l a n t a t i on f o r W e g e n e r ' s d i s e a s e . C l i n T r a ns p l a n t a t i on 4:108-11, 1990.

*80.Gruessner RWG, Tzardis PJ, Matas AJ, Dunn DL, Payne WD, Sutherland DER, Najarian JS. Ileal and colon conduits in renal transplantation. Clin Transplantation 4:125-8, 1990.

*81.Fabrega AJ, Matas AJ, Payne WD, Fryd DS, Dunn DL, Sutherland DER, Najarian JS. Ten to twenty year followup of 123 consecutive HLA-identical living related transplants. Clin Transplantation 4:145-52, 1990.

*82.Kaufman DB, Platt JL, Rabe FL, Dunn DL, Bach FH, Sutherland DER. Differential roles of Mac-1+ cells, and CD4+ and CD8+ T lymphocytes in primary nonfunction and classic rejection of islet allografts. J Exp Med 172:291-302, 1990.

*83.Wrenshall LE, Matas AJ, Canafax DM, Min DI, Sibley RJ, Dunn DL, Payne WD, Sutherland DER, Najarian JS. An increased incidence of late acute rejection episodes in recipients of cadaver renal allografts given azathioprine, cyclosporine and prednisone. Transplantation 50:233-7, 1990.

*84.Mayoral JL, Ortiz M, Singh H, Dunn DL. The protective capacity of anti-E.coli J5 murine monoclonal antibodies is dependent on binding to specific epitopes within the lipopolysaccharide molecule. Surg Forum 41:83-5, 1990.

*85.Pirenne JM, Degiovanni G, Franchimont N, Scheppens G, Meagher T, Dunn DL. Graft versus host disease after small bowel transplantation is associated with the appearance of tumor necrosis factor alpha in the serum. Surg Forum 41:389-91, 1990.

*86.Dunn DL, Najarian JS. Solid organ transplantation: where has it been, where is it going? Crit Care Clinics 6:813-9, 1990.

*87.Dunn DL. Problems related to immunosuppression: infection and malignancy occurring after solid organ transplantation. Crit Care Clinics 6:955-77, 1990.

*88.Alexander JW, Boyce S, Babcock GF, Gianotti L, Peck MD, Dunn DL, Pyles T, Childress CP, Ash SK. The process of microbial translocation. Ann Surg 212:496-512, 1990.

*89.Mayoral JL, Dunn DL. Cross-reactive murine monoclonal antibodies directed against the core/lipid A region of endotoxin inhibit production of tumor necrosis factor. J Surg Res 49:287-92, 1990.

*90.Dunn DL, Sawyer MD. Deep soft tissue infections. Curr Opinion Infect Dis 3:691-96, 1990. *91.Tzardis PJ, Gruessner RWG, Matas AJ, Payne WD, Dunn DL, Sutherland DER, Najarian JS. Fate of

native polycystic kidneys left in situ after renal transplantation. Clin Transplantation 4:309-10, 1990. *92.Bumgardner GL, Matas AJ, Payne WD, Dunn DL, Sutherland DER, Najarian JS. Renal transplantation

in patients with paraproteinemias. Clin Transplantation 4:399-405, 1990. *93.Matas AJ, Frey DJ, Gillingham KJ, Noreen HJ, Reinsmoen NL, Payne WD, Dunn DL, Sutherland

DER, Najarian JS. The impact of HLA matching on graft survival and on sensitization after a failed transplant evidence that failure of poorly matched renal transplants does not result in increased sensitization. Transplantation 50:599-607, 1990.

-1794.Gruessner RWG, Dunn DL, Tzardis PJ, Tomadze G, Adamec M, Moudry-Munns KC, Sutherland

DER. An immunological comparison of pancreas transplants alone in nonuremic patients versus simultaneous pancreas/kidney transplants in uremic diabetic patients. Transplant Proc 22:1581, 1990.

*95.Barke RA, Dunn DL, Dalmasso AP, O'Connor-Allen M, Humphrey EW. Enterococcal sepsis and lung microvascular injury in sheep. Arch Surg 125:437-40, 1990.

*96.Dunn DL. Development and potential use of antibody directed against lipopolysaccharide for the treatment of gram-negative sepsis. J Trauma 30:S100-6, 1990.

*97.Longley DG, Dunn DL, Gruessner R, Halvorsen RA Jr, Sutherland DER, Letourneau JG. Detection of pancreatic fluid and urine leakage after pancreatic transplantation: value of CT and cystography. Am J Roentgenol 155:997-1000, 1990.

98.Schlumpf RB, Morel P, Moudry-Munns KC, Dunn DL, Sutherland DER. An analysis of pancreatic retransplants with bladder drainage. Transplant Proc 22:1602, 1990.

*99.Pirenne JM, Williams JG, Mayoral JL, Nakhleh RE, Dunn DL. Resistance to graft-versus-host disease following small bowel transplantation. Transplantation 51:51-7, 1991.

*100.Dunn DL, Mayoral JL, Gillingham KJ, Loeffler CM, Brayman KL, Kramer MA, Erice A, Balfour HH, Fletcher CV, Bolman III RM, Matas AJ, Payne WD, Sutherland DER, Najarian JS. Treatment of invasive cytomegalovirus disease in solid organ transplant patients with ganciclovir. Transplantation 51:98-106, 1991.

*101.Fischel RJ, Payne WD, Gillingham KJ, Dunn DL, Sutherland DER, Matas AJ, Najarian JS. Long-term outlook for renal transplant recipients with one-year function: "Doctor, what are my chances?" Transplantation 51:118-22, 1991.

*102.Dunn DL, Morel P, Schlumpf R, Mayoral JL, Gillingham KJ, Moudry-Munns KC, Krom RAF, Gruessner RWG, Payne WD, Sutherland DER, Najarian JS. Evidence that combined procurement of pancreas and liver grafts does not affect transplant outcome. Transplantation 51:150-7, 1991.

*103.Dunn DL, Najarian JS. New approaches to the diagnosis, prevention, and treatment of cytomegalovirus infection after transplantation. Am J Surg 161:250-5, 1991.

104.Aeder MI, Fasola CG, Dunning M, Payne WD, Dunn DL, Najarian JS, Sutherland DER. Successful canine small intestinal allotransplantation: ex vivo irradiation and cyclosporine pretreatment. Transplant Proc 23:685-7, 1991.

105.Frey DJ, Matas AJ, Gillingham KJ, Canafax D, Payne WD, Dunn DL, Sutherland DER, Najarian JS. MALG vs OKT3 following renal transplantation: a randomized prospective trial. Transplant Proc 23:1048-9, 1991.

106.Gruber SA, Skjei KL, Sothern RB, Robison L, Tzardix P, Moss A, Gillingham K, Canafax DM, Matas AJ, Dunn DL. Cancer development in renal allograft recipients with conventional and cyclosporine immunosuppression. Transplant Proc 23:1104-5, 1991.

107.Fasola CG, Kim YS, Morel P, Dunn DL, Sutherland DER, Payne WD, Matas AJ, Najarian JS. Kidney retransplantation: patients with a failed second kidney transplant should be considered for a third transplant. Transplant Proc 23:1336, 1991.

108.Fischel RJ, Matas AJ, Payne WD, Gillingham KJ, Dunn DL, Sutherland DER, Najarian JS. Long-term outcome in 1-year graft survivors: comparison of diabetic and nondiabetic populations. Transplant Proc 23:1337, 1991.

109.Troppmann C, Almond PS, Escobar FS, Morel P, Papalois AE, Dunn DL, Payne WD, Sutherland DER, Matas AJ, Najarian JS. Donor age and cause of death affect cadaver renal allograft outcome. Transplant Proc 23:1365-6, 1991.

110.Gruber SA, Chavers B, Skjei KL, Sothern RB, Robison L, Tzardis P, Moss A, Gillingham K, Canafax DM, Najarian JS, Matas AJ, Dunn DL. De novo cancer after pediatric kidney transplantation. Transplant Proc 23:1373-4, 1991.

-18111.Almond PS, Morel P, Matas AJ, Gillingham KJ, Chau KS, Brown A, Kashtan CE, Mauer SM, Chavers B,

Nevins TE, Dunn DL, Sutherland DER, Payne WD, Najarian JS. Transplanted children with long-term graft functions have an excellent quality of life. Transplant Proc 23:1380-1, 1991.

112.Nakhleh RE, Gruessner RWG, Tzardis PJ, Brayman K, Dunn DL, Sutherland DER. Pancreas transplant pathology: an immunohistochemical comparison of allografts with rejection, syngeneic grafts, and chronic pancreatitis. Transplant Proc 23:1598-9, 1991.

113.Morel P, Gillingham KJ, Moudry-Munns KC, Dunn DL, Najarian JS, Sutherland DER. Factors influencing pancreas transplant outcome: Cox proportional hazard regression analysis of a single institution's experience with 357 cases. Transplant Proc 23:1630-3, 1991.

114.Sutherland DER, Moudry-Munns KC, Gillingham KJ, Najarian JS, Dunn DL. Solitary pancreas transplantation: alone in nonuremic and after a kidney in uremic diabetic patients. Transplant Proc 23:1637-9, 1991.

115.Morel P, Gillingham KJ, Schlumpf R, Chau C, Moudry-Munns KC, Payne WD, Najarian JS, Sutherland DER, Dunn DL. Effect of simultaneous liver retrieval team, retrieval team, and preservation time on cadaver whole-organ bladder-drained pancreatic allograft survival rates. Transplant Proc 23:1640-3, 1991.

*116.Mayoral JL, Loeffler CM, Fasola CG, Kramer MA, Orrom WJ, Matas AJ, Najarian JS, Dunn DL. Diagnosis and treatment of cytomegalovirus disease in transplant patients based upon gastrointestinal tract manifestations. Arch Surg 126:202-6, 1991.

*117.Nakhleh RE, Gruessner RWG, Swanson PE, Tzardis PJ, Brayman KL, Dunn DL, Sutherland DER. Pancreas transplant pathology: a morphologic, immunohistochemical, and electron microscopic comparison of allogeneic grafts with rejection, syngeneic grafts, and chronic pancreatitis. Am J Surg Path 15:246-56, 1991.

118.Balfour HH Jr, Fletcher CV, Dunn DL. Prevention of cytomegalovirus disease with oral acyclovir. Transplant Proc 23:17-9, 1991.

*119.Gruessner RWG, Manivel C, Dunn DL, Sutherland DER. Pancreaticoduodenal transplantation with enteric drainage following native total pancreatectomy for chronic pancreatitis: a case report. Pancreas 6:479-88, 1991.

*120.Nakhleh RE, Gruessner RWG, Tzardis PJ, Dunn DL, Sutherland DER. Pathology of transplanted human duode na l t issue: a his tolo gic st udy, w ith c om parison to pa nc r e atic path ology in re se cted pancreaticoduodenal transplants. Clin Transplantation 5:241-7, 1991.

*121.Pirenne J, Nakhleh RE, Dunn DL. Graft-versus-host disease after multiorgan transplantation. J Surg Res 50:622-8, 1991.

*122.Fletcher CV, Englund JA, Edelman CK, Gross CR, Dunn DL, Balfour HH. Pharmacologic basis for high-dose oral acyclovir prophylaxis of cytomegalovirus disease in renal allograft recipients. Antimicrob Agents Chemother 35:938-43, 1991.

123.Dunn DL. Applications of immunology in clinical surgery: Infection. Proceedings from the 1990 Surgical Research and Education Symposium of the American College of Surgeons 2:7-12, 1991.

*124.Erice A, Rhame FS, Heussner R, Dunn DL, Balfour HH. Human immunodeficiency virus infection in solid organ transplantation: report of 5 cases and review of the literature. Rev Infect Dis 13:537-47, 1991.

*125.Pirenne J, Degiovanni G, Dunn DL. Mechanisms of graft-versus-host disease produced by small bowel transplantation. Acta Chirurgica Austriaca 1:11-16, 1991.

*126 .Mayoral JL, Cody CS, Burd RS, Sawyer MD, Raymond CS, Dunn DL. Lipopolysaccharide uptake by macrophages is enhanced by anti-lipopolysaccharide monoclonal antibodies. Surg Forum 42:110-2, 1991.

-19*127 .Dunn DL. Role of endotoxin and host cytokines in septic shock. Chest 100:164S-8S, 1991. *128.Morel P, Sutherland DER, Almond PS, Stoblen F, Matas AJ, Najarian JS, Dunn DL. Assessment of renal

function in Type I diabetic patients after kidney, pancreas or combined kidney-pancreas transplantation. Transplantation 51:1184-9, 1991.

*129.Sawyer MD, Dunn DL. Deep soft tissue infections. Curr Opinion Infect Dis 4:649-54, 1991. *130.Morel P, Schlumpf R, Dunn DL, Moudry-Munns KC, Najarian JS, Sutherland DER. Pancreas

retransplants compared with primary transplants. Transplantation 51:825-33, 1991. *131.Morel P, Brayman KL, Goetz FC, Kendall DM, Moudry KC, Chau C, Balakumar M, Stevens B,

Dunn DL, Sutherland DER. Long-term metabolic function of pancreas transplants and influence of rejection episodes. Transplantation 51:990-1000, 1991.

*132.Sawyer MS, Dunn DL. Appropriate use of antimicrobial agents. Nine principles. Postgrad Medicine 90:115-22, 1991.

133.Dunn DL. Microbial translocation. Surgical Residents' Newsletter 2:2-6, 1991. *134.Gudnason T, Dunn DL, Brown NA, Balfour HH Jr. Human herpes virus 6 infections in hospitalized renal

transplant recipients. Clin Transplantation 5:359-64, 1991. *135.Greenman RL, Schein RMH, Martin MA, Wenzel RP, MacIntyre NR, Emmanuel G, Chmel H,

Kohler RB, McCarthy M, Plouffe J, Russell JA, and the XOMA Sepsis Study Group. A controlled clinical trial of E5 murine monoclonal IgM antibody to endotoxin in the treatment of gram-negative sepsis. JAMA 266:1097-1102, 1991.

*136.Williams JG, Pirenne J, Mayoral JM, Orrom WJ, Nakhleh RE, Condie R, Dunn DL. Effect of donor pre-treatment with anti-lymphocyte globulin on small bowel transplantation in rats. Br J Surgery 78:1176-7, 1991.

*137.Morel P, Troppmann C, Almond PS, Schlumpf R, Gillingham KJ, Sutherland DER, Dunn DL, Payne WD, Matas AJ, Najarian JS. Multiorgan procurement does not affect the immediate outcome of kidney transplants. Clin Transplantation 5:381-5, 1991.

*138.Schweitzer EJ, Matas AJ, Gillingham KJ, Payne WD, Gores PF, Dunn DL, Sutherland DER, Najarian JS. Causes of renal allograft loss: progress in the 1980s, challenges for the 1990s. Ann Surg 214:679-88, 1991.

*139.Pirenne J, D'Silva M, Nakhleh RE, Lee S, Dunn DL. Multiorgan transplantation in the rat: development of a new microsurgical model. Microsurgery 12:378-84, 1991.

*140.Stephanian E, Gruber SA, Dunn DL, Matas AJ. Posttransplant lymphoproliferative disorders. Transplantation Reviews 5:120-9, 1991.

*141.Fasola CG, Kim YS, Aeder MI, Dunning M, Mueller R, Nakhleh RE, Almond S, Payne WD, Dunn DL. Pretransplant immunotherapy can prolong function of small bowel allografts in dogs. Curr Surgery 48:469-73, 1991.

*142.Almond PS, Matas AJ, Gillingham KJ, Troppmann C, Payne WD, Dunn DL, Sutherland DER, Najarian JS. Risk factors for second renal allografts immunosuppressed with cyclosporine. Transplantation 258:253-8, 1991.

*143.Sutherland DE, Gruessner R, Gillingham K, Moundry-Munns K, Dunn DL, Brayman K, Morel P, Najarian JS. A single institutions experience with solitary pancreas transplantation: a multivariate analysis of factors leading to improved outcome. Cli n Transplant 141-52,1991.

*144.Schlumpf R, Morel P, Dunn DL, Payne W, Sutherland D. Simultaneous removal of liver and pancreas does not have an effect on results of transplantation of these organs. Helvet Chirug Acta 57:859-63, 1991.

145.Nakhleh RE, Gruessner RW, Tzardis PJ, Brayman K, Dunn DL, Sutherland DE. Pancreas transplant pathology: an immunohistochemical comparison of allografts with rejection, syngeneic graft, and chronic pancreatitis. Transplant Proc 23:1589-9, 1991.

-20

146.Moudry-Munns KC, Gillingham K, Dunn DL, Sutherland DE. Mortality risk for technically successful vs. technically failed bladder drained pancreas transplants and causes of death. Transplant Proc 24:863-5, 1992.

*147.Brayman KL, Stephanian E, Matas AJ, Schmidt W, Payne WD, Sutherland DER, Gores PF, Najarian JS, Dunn DL. Analysis of infectious complications occurring after solid-organ transplantation. Arch Surg 127:38-48, 1992.

*148.Almond PS, Matas AJ, Gillingham K, Moss A, Mauer M, Chavers B, Nevins T, Kashtan K, Dunn DL, Payne W, Sutherland D, Gores P, Najarian JS. Pediatric renal transplants--Results with sequential immunosuppression. Transplantation 53:46-51, 1992.

*149.Almond PS, Gillingham KJ, Sibley R, Moss A, Melin M, Leventhal J, Manivel C, Kyriakides P, Payne WD, Dunn DL, Sutherland DER, Gores PF, Najarian JS. Matas AJ. Renal transplant function after ten years of cyclosporine. Transplantation 53:316-23, 1992.

*150.Cerra FB, Maddaus MA, Dunn DL, Wells CL, Konstantinides NN, Lehmann SL, Mann HJ. Selective gut decontamination reduces nosocomial infections and length of stay but not mortality or organ failure in surgical intensive care unit patients. Arch Surg 127:163-9, 1992.

*151.Matas AJ, Payne WD, Gillingham KJ, Dunn DL, Sutherland DER, Najarian JS. Optimizing the immediate posttransplant prednisone dose - a prospective randomized trial. Clin Transplantation 6:73-6, 1992.

*152.Cody CS, Burd RS, Mayoral JL, Dunn DL. Protective anti-lipopolysaccharide monoclonal antibodies inhibit tumor necrosis factor production. J Surg Res 52:314-9, 1992.

*153.Wells CL, Barton RG, Walvatne CS, Dunn DL, Cerra FB. Intestinal bacterial flora, intestinal pathology, and lipopolysaccharide-induced translocation of intestinal bacteria. Circ Shock 37:117-23, 1992.

*154.Sutherland DER, Dunn DL, Moudry-Munns K, Gillingham K, Najarian JS. Pancreas transplants in nonuremic and posturemic diabetic patients. Transplant Proc 24:780-1, 1992.

155.Stephanian E, Gruessner RWG, Brayman KL, Gores P, Dunn DL, Sutherland DER. Converting exocrine drainage from bladder to bowel in recipients of whole pancreaticoduodenal transplants. Transplant Proc 24:808-10, 1992.

156.Morel P, Chau C, Brayman K, Moudry-Munns K, Gillingham K, Stevens B, Dunn DL, Goetz FC, Najarian JS, Sutherland DER. Quality of metabolic control at 2 to 12 years after a pancreas transplant. Transplant Proc 24:835-8, 1992.

157.Cheung AHS, Sutherland DER, Dunn DL, Moudry-Munns KC, McHugh LE, Gillingham KJ, Najarian JS, Matas AJ. Morbidity following simultaneous pancreas-kidney transplants vs kidney transplants alone in diabetic patients. Transplant Proc 24:866-8, 1992.

158.Brayman KL, Moss A, Morel P, Nakhleh R, Dunn DL, Sutherland DER. Exocrine dysfunction evaluation of bladder-drained pancreaticoduodenal transplants using a transcystoscopic biopsy technique. Transplant Proc 24:901-2, 1992.

159.Pirenne J, D'Silva M, Nakhleh RE, Lee S, Jaquet N, Dunn DL. Pancreas induces graft-vs-host disease when transplanted en bloc with liver and small bowel. Transplant Proc 24:915-7, 1992.

160.Mayoral JL, Brayman KL, Gillingham KJ, Sutherland DER, Najarian JS, Dunn DL. Influence of pretransplant cytomegalovirus serology and treatment of rejection upon disease after kidney and kidney plus pancreas transplantation. Transplant Proc 24:929-31, 1992.

*161.Cheung AHS, Sutherland DER, Gillingham KJ, McHugh LE, Moudry-Munns KC, Dunn DL, Najarian JS, Matas AJ. Simultaneous pancreas-kidney transplant versus kidney transplant alone in diabetic patients. Kidney International 41:924-9, 1992.

-21*162.Berg LC, Copenhaver CM, Morrison VA, Gruber SA, Dunn DL, Gajl-Peczalska K, Stickler JG. B-cell

lymphoproliferative disorders in solid-organ transplant patients: detection of Epstein-Barr virus by in situ hybridization. Hum Pathol 23:159-63, 1992.

*163.Burd RS, Raymond CS, Dunn DL. Endotoxin promotes synergistic lethality during concurrent Escherichia coli and Candida albicans infection. J Surg Res 52:537-42, 1992.

*164.Frey DJ, Matas AJ, Gillingham KJ, Canafax D, Payne WD, Dunn DL, Sutherland DER, Najarian JS. Sequentia l therapy a prospec tive randomize d tria l of MALG versus OKT3 for prophylac tic immunosuppression in cadaver renal allograft recipients. Transplantation 54:50-6, 1992.

*165.Gores PF, Gillingham KJ, Dunn DL, Moudry-Munns KC, Najarian JS, Sutherland DER. Donor hyperglycemia as a minor risk factor and immunologic variables as major risk factors for pancreas allograft loss in a multivariate analysis of a single institution's experience. Ann Surg 215:217-30, 1992.

166.Sawyer MD, Dunn DL. Antimicrobial therapy of intra-abdominal sepsis. Infect Dis Clin North Am 6:545-70, 1992.

167.Farber MS, Dunn DL. Preventing CMV infection in cardiac transplant recipients. J Crit Illness, 7:1758- 61, 1992.

*168.Camarata PJ, Dunn DL, Farney AC, Parker RG, Seljeskog EL. Continual intracavitary administration of amphotericin B used as an adjunct in the treatment of Apergillus brain abscess: case report and review of the literature. Neurosurg 3 1:575-9, 1992.

*169.Erice A, Holm MA, Gill PC, Henry S, Dirksen CL, Dunn DL, Hillam RP, Balfour HH. Cytomegalovirus (CMV) antigenemia assay is more sensitive than shell vial cultures for rapid detection of CMV in polymorphonuclear blood leukocytes. J Clin Microbiol 30:2822-5, 1992.

*170.Stephanian E, Brayman KL, Manivel JC, Sutherland DER, Dunn DL. Fulminant post-transplant lymphoproliferative disorder presenting as multisystem organ failure. Clin Transplantation 6:361-8, 1992.

*171.Dunn DL, Mayoral JL, Gillingham KJ, Sawyer MD, Kramer MA, Statz CL, McHugh L, Matas AJ, Gores PF, Payne WD, Sutherland DER, Najarian JS. Simultaneous treatment of concurrent rejection and tissue invasive cytomegalovirus disease without detrimental effects upon patient or allograft survival. Clin Transplantation 6:413-20, 1992.

*172.Nevins TE, Dunn DL. Use of ganciclovir for cytomegalovirus infection. J Am Soc Nephrol 2:S270-3, 1992.

*173.Stephanian E, Gruessner RWG, Brayman KL, Gores P, Dunn DL, Najarian JS, Sutherland DER. C onversion of exocr ine secre tions from bla dder to e nter ic draina ge in r ecipients of whole pancreaticoduodenal transplants. Ann Surg 216:663-72, 1992.

*174.Boivin G, Erice A, Crane DD, Dunn DL, Balfour HH. Acyclovir susceptibilities of herpes simplex virus strains isolated from solid organ transplant recipients after acyclovir or ganciclovir prophylaxis. Antimicrob Agents Chemother 37:357-9, 1993.

*175.Burd RS, Cody CS, Raymond CS, Dunn DL. Anti-endotoxin monoclonal antibodies protect by enhancing bacterial and endotoxin clearance. Arch Surg 128:145-51, 1993.

*1 7 6.Sa w ye r M D, Ma y ora l JL, Gi l l in g ham K J, Kra me r M A, Dunn DL. Tr ea tm e n t o f recu rre n t cytomegalovirus disease in patients receiving solid organ transplants. Arch Surg 128:165-70, 1993.

177.Troppmann C, Almond PS, Payne WD, Dunn DL, Gores PF, Gruessner RW, Sutherland DE, Matas AJ, Najarian JS. Does acute tubular necrosis affect renal transplant outcome? The impact of rejection episodes. Transplant Proc 25:905, 1993.

178.Basadonna GP, Matas AJ, Gillingham KJ, Payne WD, Dunn DL, Sutherland DE, Gores PF, Gruessner RW, Arrazola L, Najarian JS. Relationship between early versus late acute rejection and onset of chronic rejection in kidney transplantation. Transplant Proc 25:910-1, 1993.

-22179.Almond PS, Matas AJ, Gillingham KJ, Dunn DL, Payne WD, Gores P, Gruessner R, Najarian JS.

Predictors of chronic rejection in renal transplant recipients. Transplant Proc 25:936, 1993. 180.Gruessner RW, Stephanian E, Dunn DL, Gruessner AC, Najarian JS, Sutherland DE. Cystoenteric

conversion after whole pancreaticoduodenal transplantation: indications, risk factors, and outcome. Transplant Proc 25:1179-81, 1993.

181.Cheung AH, Matas AJ, Gruessner RW, Dunn DL, Moudry-Munns KC, Najarian JS, Sutherland DE. Should uremic diabetic patients who want a pancreas transplant receive a simultaneous cadaver kidney-pancreas transplant or a living related donor kidney first followed by cadaver pancreas transplant? Transplant Proc 25:1184-5, 1993.

182.Casanova D, Gruessner R, Brayman K, Jessurun J, Dunn DL, Xenos E, Sutherland DE. Retrospective analysis of the role of pancreatic biopsy (open and transcystoscopic technique) in the management of solitary pancreas transplants. Transplant Proc 25:1192-3, 1993.

183.Gruessner A, Gruessner R, Moudry-Munns K, Dunn DL, Najarian JS, Sutherland DE. Influence of multiple factors (age, transplant number, recipient category, donor source) on outcome of pancreas transplantation at one institution. Transplant Proc 25:1303-5, 1993.

184.Kaufman DB, Matas AJ, Arrazola L, Gillingham KJ, Sutherland DE, Payne WD, Dunn DL, Gores PF, Najarian JS. Transplantation of kidneys from zero haplotype-matched living donors and from distantly related and unrelated donors in the cyclosporine era. Transplant Proc 25:1530-1, 1993.

185.Fasola CG, Kim YS, Dunning M, Condie RM, Kurle J, Manivel JC, Schlumpf R, Payne WD, Sutherland DER, Najarian JS, Dunn DL. Successful canine small bowel preservation in simple cold storage for 48 hours using a dextran-40-based solution. Transplant Proc 25:1576-9, 1993.

186.Canafax DM, Carleton BC, Matas AJ, Payne WD, Dunn DL, Sutherland DE, Najarian JS. Effects of three immunosuppressive drug protocols on cadaver renal transplantation costs after four years of therapy. Transplant Proc 25:1692-3, 1993.

*187.Burd RS, Raymond CS, Ratz CA, Dunn DL. A rapid procedure for purifying IgM monoclonal antibodies from murine ascites using a DEAE-disk. Hybridoma 12:135-42, 1993.

*188.Almond PS, Matas A, Gillingham K, Dunn DL, Payne WD, Gores P, Gruessner R, Najarian JS. Risk factors for chronic rejection in renal allograft recipients. Transplantation 55:752-7, 1993.

*189.Basadonna GP, Matas AJ, Gillingham KJ, Payne WD, Dunn DL, Sutherland DER, Gores PF, Gruessner RWG, Najarian JS. Early versus late acute renal allograft rejection: impact on chronic rejection. Transplantation 55:993-5, 1993.

*190.Battafarano RJ, Burd RS, Cody CS, Kellogg TA, Raymond CS, Ratz CA, Dunn DL. Anti-lipopolysaccharide monoclonal antibodies inhibit macrophage TNF messenger RNA synthesis in vitro. J Surg Res 54:342-8, 1993.

*191.Burd RS, Battafarano RJ, Cody CS, Farber MS, Ratz CA, Dunn DL. Anti-endotoxin monoclonal antibodies inhibit secretion of tumor necrosis factor- by two distinct mechanisms. Ann Surg 218:250-61, 1993.

*192.Boivin G, Erice A, Crane DD, Dunn DL, Balfour HH. Ganciclovir susceptibilities of cytomegalovirus (CMV) isolates from solid organ transplant recipients with CMV viremia after antiviral prophylaxis. J Infect Dis 168:332-5, 1993.

*193.Pirenne J, D'Silva M, Degiovanni G, Jacquet N, Dunn DL. Relevance of tumor necrosis factor to graftversus-host disease after small bowel transplantation. Transpl International 6:258-62, 1993.

*194.Dunn DL. Use of novel therapeutic agents for the treatment of serious infection. Am J Surg 166:449-55, 1993.

*195.Sutherland DER, Gores P, Farney A, Wahoff DC, Matas AJ, Dunn DL, Gruessner RWG, Najarian JS. Evolution of kidney, pancreas, and islet transplantation for diabetes at the University of Minnesota. Am J Surg 166:456-89,1993.

-23*196.Dunn DL. Monoclonal antibodies for diagnosis and treatment. Arch Surg 128:1274-80, 1993. 197.Dunn DL. Controversies regarding the use of anti-endotoxin monoclonal antibodies. Infect Dis Clin

Practice 2:456-62, 1993. 198.Dunn DL. Anti-cytokine therapies in sepsis. Perspect Gen Laparoscopic Surg 1:45-57, 1993. 199.Gruessner AC, Barrou B, Jones J, Dunn DL, Moudry-Munns K, Najarian JS, Sutherland DER,

Gruessner RW. Donor impact on outcome of bladder-drained pancreas transplants. Transplant Proc 25:3114-5, 1993.

200.Dunn DL. Presidential Address. History repeats itself: Connections and causality in the study of surgical infections. Arch Surg 129:21-6, 1994.

*201.Jones JW, Gillingham KJ, Sutherland DER, Payne WD, Dunn DL, Gores PF, Gruessner RWG, Najarian JS, Matas AJ. Successful long-term outcome with 0-haplotype-matched living-related kidney donors. Transplantation 57:512-5, 1994.

*202.Battafarano RJ, Burd RS, Kurrelmeyer KM, Ratz CA, Dunn DL. Inhibition of splenic macrophage tumor necrosis factor- secretion in vivo by antilipopolysaccharide monoclonal antibodies. Arch Surg 129:179- 86, 1994.

*203.Dunn DL, Gillingham KJ, Kramer MA, Schmidt WJ, Erice A, Balfour HH, Gores PF, Gruessner RWG, Matas AJ, Payne WD, Sutherland DER, Najarian JS. A prospective randomized study of acyclovir versus ganciclovir plus human immune globulin prophylaxis of cytomegalovirus infection after solid organ transplantation. Transplantation 57:876-84, 1994.

204.Dunn DL. Gram-negative bacterial sepsis and sepsis syndrome. Surg Clin North Am 74:621-35, 1994. *205.Gruessner RWG, Dunn DL, Gruessner AC, Matas AJ, Najarian JS, Sutherland DER. Recipient

risk factors have an impact on technical failure and patient and graft survival rates in bladder-drained pancreas transplants. Transplantation 57:1598-1606, 1994.

*206.Burd RS, Gillingham KJ, Farber MS, Statz CL, Kramer MA, Najarian JS, Dunn DL. Diagnosis and treatment of cytomegalovirus disease in pediatric renal transplant recipients. J Pediatr Surg 29:1049-54, 1994.

*207.Gruber SA, Gillingham K, Sothern RB, Stephanian E, Matas AJ, Dunn DL. De novo cancer in cyclosporine-treated and non-cyclosporine-treated adult primary renal allograft recipients. Clin Transplantation 8:388-95, 1994.

208.Sutherland DER, Gruessner RWG, Dunn DL, Moudry-Munns K, Gruessner A, Najarian JS. Pancreas transplants from living related donors. Transplant Proc 26:443-5, 1994.

209.Gruessner RWG, Troppmann C, Barrou B, Dunn DL, Moudry-Munns KC, Najarian JS, Sutherland DER, Gruessner AC. Assessment of donor and recipient risk factors on pancreas transplant outcome. Transplant Proc 26:437-8, 1994.

*210.Morrison VA, Dunn DL, Manivel JC, Gajl-Peczalska KJ, Peterson BA. Clinical characteristics of post-transplant lymphoproliferative disorders. Am J Med 97:14-24, 1994.

211.Gruber SA, Stephanian E, Dunn DL. A complicated case of skin cancer in a renal allograft recipient. Transplantation Science 1:17-9, 1994.

212.Gruber SA, Gillingham KJ, Sothern RB, Stephanian E, Chavers B, Matas AJ, Dunn DL. Cancer development in pediatric primary renal allograft recipients. Transplant Proc 26:3-4, 1994.

213.Granger DK, Burd RS, Schmidt WJ, Dunn DL, Matas AJ. Incidence and timing of infections in pediatric renal transplant recipients in the cyclosporine era. Transplant Proc 26:64, 1994.

214.Dunn DL. Prophylaxis and treatment of cytomegalovirus infection in solid organ transplant patients. Transplant Immunol Letters 4:4, 16-9, 1994.

*215.Kim SK, Battafarano RJ, Dahlberg PS, Dunn DL. Protective effect of monophosphoryl lipid A (MPLA) during systemic candidiasis in neutropenic and normal mice. Surg Forum 65:50-1, 1994.

-24*216.Everett JE, Wahoff DC, Statz C, Gillingham KJ, Gruessner A, Gruessner RWG, Gores PF,

Sutherland DER, Dunn DL. Characterization and impact of wound infection after pancreas transplantation. Arch Surg 129:1310-7, 1994.

*217.Hakim NS, Benedetti E, Pirenne J, Gillingham KJ, Payne WD, Dunn DL, Sutherland DE, Gruessner R, Gores PF, Matas AJ, et al. Complications of ureterovesical anastomosis in kidney transplant patients: the Minnesota experience. Clin Transplantation 8:504-7, 1994.

*218.Benedetti E, Fryer J, Matas AJ, Sutherland DE, Payne WD, Dunn DL, Gores PF, Gruessner RW, Najarian JS. Kidney transplant outcome with and without right renal vein extension. Clin Transplantation 8:416-7, 1994.

219.Troppmann C, Gruessner RW, Dunn DL, Fasola C, Najarian JS, Sutherland DER. Is transplant pancreatectomy after graft failure necessary? Transplant Proc 26:455, 1994.

220.Troppmann C, Dunn DL, Najarian JS, Sutherland DER, Gruessner AC, Gruessner RW. Operative reintervention following early complications after pancreas transplantation. Transplant Proc 26:454, 1994.

221.Troppmann C, Gruessner RW, Matas AJ, Dunn DL, Stevens RB, Najarian JS, Sutherland DER. Results with renal transplants performed after previous solitary pancreas transplants. Transplant Proc 26:448-9, 1994.

222.Gruessner RW, Troppmann C, Barrou B, Dunn DL, Moudry-Munns KC, Najarian JS, Sutherland DER, Gruessner AC. Assessment of donor and recipient risk factors on pancreas transplant outcome. Transplant Proc 26:437-8, 1994.

223.Fasola CG, Gillingham KJ, Troppmann C, Gruessner RW, Gores PF, Dunn DL, Payne WD, Sutherland DER, Matas AJ, Najarian JS. Kidney transplant or retransplant can effectively treat congenital nephrotic syndrome: a single-center experience. Transplant Proc 26:9, 1994.

224.Fasola CG, Gillingham KJ, Troppmann C, Gruessner RW, Gores PF, Dunn DL, Payne WD, Sutherland DER, Matas AJ, Najarian JS. Pediatric kidney retransplantation: 30 years of experience at a single institution. Transplant Proc 26:48, 1994.

225.Troppmann C, Almond PS, Fasola C, Benedetti E, Gruessner RW, Dunn DL, Gores PF, Payne WD, Matas AJ, Najarian JS. Effect of Minnesota antilymphocyte globulin on T-lymphocytes and their subsets during induction therapy in pediatric renal transplantation. Transplant Proc 26:26-7, 1994.

*226.Carlson JW, Fowler JM, Saltzman AK, Carter JR, Chen MD, Mitchell SK, Dunn DL, Carson LF, Adcock LL, Twiggs LB. Chemoprophylaxis with oral ciprofloxacin in ovarian cancer patients receiving taxol. Gynecol Oncol 55:415-20, 1994.

*227.Wells CL, Juni BA, Cameron SB, Mason KA, Dunn DL, Ferrieri P, Rhame FS. Stool carriage, clinical isolation, and mortality during an outbreak of vancomycin-resistant enterococci in hospitalized medial and/or surgical patients. Clin Infect Dis 21:45-50, 1995.

*228.Battafarano RJ, Dahlberg PS, Ratz CA, Johnston JW, Gray BH, Haseman JR, Mayo KH, Dunn DL. Peptide derivatives of three distinct lipopolysaccharide binding proteins inhibit lipopolysaccharide-induced tumor necrosis factor- secretion in vitro. Surgery 118:318-24, 1995.

*229.Dahlberg PS, Battafarano RJ, Acton RD, Ratz CR, Johnston JW, Dunn DL. Active but not passive immunization protects against gram-negative bacterial infection. Surg Forum 66:63-5, 1995.

*230.Mauch T, Crouch NA, Freese DK, Braunlin EA, Dunn DL, Kashton CE. Antibody response of pediatric solid organ transplant recipients to immunization against influenza virus. J Ped 127:957-60, 1995.

*231.Matas AJ, Almond PS, Moss A, Gillingham KJ, Sibley R, Payne WD, Dunn DL, Gruessner RWG, Sutherland DER, Manivel C, Najarian JS. Effect of cyclosporine on renal function in kidney transplant recipients: a 12-year follow-up. Clin Transplant 9:450-3, 1995.

-25*232.Battafarano RJ, Kim SK, Dahlberg PS, Farber MS, Ratz CA, Johnston JW, Dunn DL. Lymphocyte-

derived cytokines augment macrophage tumor necrosis factor- and interleukin-6 secretion during experimental gram-negative bacterial sepsis. J Surg Res 58:739-45, 1995.

233.Wahoff DC, Papalois BE, Najarian JS, Nelson LA, Dunn DL, Farney AC, Sutherland DE. Clinical islet au to tr a n s p la nta t i on a ft e r p anc re a te c t om y: de te r m i na n t s of s ucc e s s a n d i m p l ica t io n s f or allotransplantation? Transplant Proc 27:3 161, 1995.

*234.Wahoff DC, Papalois BE, Najarian JS, Kendall DM, Farney AC, Leone JP, Jessurun J, Dunn DL, Robertson RP, Sutherland DE. Autologous islet transplantation to prevent diabetes after pancreatic resection. Ann Surg 222:562-75, 1995.

*235.Gruessner RW, Fryer JP, Fasola C, Nakhleh RE, Gruessner AC, Kim S, Dunn DL, Pirenne J, Bekersky I, Benedetti E, Troppmann C. A prospective study of FK506 versus CsA and pig ATG in a porcine model of small bowel transplantation. Transplantation 59:164-71, 1995.

*236.Erice A, Holm MA, Sanjuan MV, Dunn DL, Gill PC, Balfour HH Jr. Evaluation of CMV-vue antigenemia assay for rapid detection of cytomegalovirus in mixed-leukocyte blood fractions. J Clin Micro 33:1014-5, 1995.

*237.Benedetti E, Troppmann C, Gillingham K, Sutherland DE, Payne WD, Dunn DL, Matas AJ, Najarian JS, Grussner RW. Short- and long-term outcomes of kidney transplants with multiple renal arteries. Ann Surg 221:406-14, 1995.

*238.Troppman C, Papalois BE, Chiou A, Benedetti E, Dunn DL, Matas AJ, Najarian JS, Gruessner RW. Incidence, complications, treatment, and outcome of ulcers of the upper gastrointestinal tract after renal transplantation during the cyclosporine era. J Am Coll Surg 180:433-43, 1995.

239.Beebe DS, Kim S, Belani KG, Fryer J, Benedetti E, Moon S, Fasola C, Pirenne J, Dunn DL, Gruessner RW. Endotoxemia during small bowel transplantation in pigs. Transplant Proc 27:593-4, 1995.

240.Pirenne J, Williams JG, Kim S, Fryer J, Benedetti E, Hakim NS, Medot M, Najarian JS, Gruessner RW, Dunn DL. Importance of lymphoid tissue for survival of small bowel allografts. Transplant Proc 27:1359-60, 1995.

*241.Sielaff TD, Everett JE, Shumway SJ, Wahoff DC, Bolman RM III, Dunn DL. Mycoplasma hominis infections occurring in cardiovascular surgical patients. Ann Thoracic Surg 61:99-103, 1996.

*242.Fryer JP, Kim S, Wells CL, Fasola C, Jechorek RP, Dunn DL, Pirenne J, Arazola L, Gruessner RWG. Bacterial translocation in a large-animal model of small-bowel transplantation: portal vs systemic venous drainage and the effect of tacrolimus immunosuppression. Arch Surg 131:77-84, 1996.

*243.Dahlberg PS, Sielaff TD, Dunn DL. Emerging resistance in Staphylococci and Enterococci. Infect Dis Clin Practice 5:S49-S56, 1996.

*244.Gruessner RWG, Fasola C, Fryer J, Nakhleh RE, Kim S, Gruessner AC, Beebe D, Dunn DL, Troppmann C, Najarian JS. Quadruple immunosuppression in a pig model of small bowel transplantation. J Surg Res 61:260-6, 1996.

245.Sawyer MD, Dunn DL. Serious bacterial infections of the skin and soft tissues. Curr Opinion Infect Dis 8:293-7, 1995.

246.Pirenne J, Medot, Battafarano R, Benedetti E, Kim S, Dunn DL. Does endotoxin accelerate rejection in a cardiac allograft model? Transplant Proc 28:2463-4, 1996

247.Dunn DL. Presidential Address. Projections. J Surg Res 63:1-5, 1996. 248.Ulevitch RJ, Dunn DL, Fink MP, Taylor CE. Endotoxin related intracellular pathways: implications for

therapeutic intervention. Shock 6:1-2, 1996. *249.Troppmann C, Gruessner AC, Benedetti E, Papalois BE, Dunn DL, Najarian JS, Sutherland DE,

Gruessner RW. Vascular graft thrombosis after pancreatic transplantation: univariate and multivariate operative and nonoperative risk factor analysis. J Am Coll Surg 182:362-3, 1996.

-26*250.Matas AJ, Lawson W, McHugh L, Gillingham K, Payne WD, Dunn DL, Gruessner RWG,

Sutherland DER, Najarian JS. Employment patterns after successful kidney transplantation. Transplantation 61:729- 33, 1996.

251.Uknis ME, Dunn DL. Nosocomial infections and sepsis syndrome in critically ill surgical patients. Current Opinion in Critical Care 2:304-10, 1996.

*252.Dahlberg PS, Acton RD, Battafarano RJ, Uknis ME, Ratz CA, Johnston JW, Haseman JR, Gray BH, Dunn DL. A novel endotoxin antagonist attenuates tumor necrosis factor alpha secretion. J Surg Res 63:44-8, 1996.

*253.Benedetti E, Troppmann C, Gruessner AC, Sutherland DER, Dunn DL, Gruessner RWG. Pancreas graft loss caused by intra-abdominal infection. Arch Surg 131:1054-60, 1996.

*254.Troppmann C, Gillingham KJ, Gruessner RW, Dunn DL, Payne WD, Najarian JS, Matas AJ. Delayed graft function in the absence of rejection has no long-term impact. A study of cadaver kidney recipients with good graft function at 1 year after transplantation. Transplantation 61:1331-7, 1996.

*255.Benedetti E, Gruessner AC, Troppmann C, Papalois BE, Sutherland DER, Dunn DL, Gruessner RW. Intra-abdominal fungal infections after pancreatic transplantation: incidence, treatment, and outcome. J Am Coll Surg 183:307-16, 1996.

*256.Dahlberg PS, Acton RD, Uknis ME, Klaerner HG, Johnston JW, Levelle CD, Gray BH, Dunn DL. Macrophages expressing a fusion protein derived from bactericidal/permeability-increasing protein and IgG are resistant to endotoxin. Arch Surg 131:1173-8, 1996.

*257.Acton RD, Dahlberg PS, Uknis ME, Klaerner HG, Fink GS, Norman JG, Dunn DL. Differential sensitivity to Escherichia coli infection of mice lacking tumor necrosis factor p55 and IL-1 p80 receptors. Arch Surg 131:1216-21, 1996

258.Bullard KM, Dunn DL. Diagnosis and treatment of bacteremia and intravascular catheter infections. Am J Surg 172:S13-9, 1996.

259.Doutrelepont JM, DePauw L, Gruber SA, Dunn DL, Qunibi W, Kinnaert P, Verserstraeten P, Penn I, Abramowicz D. Renal transplantation exposes patients with previous Kaposi's sarcoma to a high risk of recurrence. Transplantation 62:463-6, 1996.

*260.Wrenshall LW, McHugh L, Felton P, Dunn DL, Matas AJ. Pregnancy after donor nephrectomy. Transplantation 62:1934-6, 1996.

*261.Matas AJ, Gillingham KJ, Payne WD, Dunn DL, Gruessner RW, Sutherland DE, Schmidt W, Najarian JS. A third kidney transplant: cost-effective treatment for end-stage renal disease? Clin Transplantation 10:516-20, 1996.

*262.Pirenne J, Benedetti E, Dunn DL. Graft versus host response: clinical and biological relevance after transplantation of solid organs. Transplant Rev 10:46-68, 1996.

*263.Hakim NS, Gruessner AC, Papalois BE, Troppmann C, Dunn DL, Sutherland DE, Gruessner RW. Duodenal complication in bladder-drained pancreas transplantation. Surgery 121:618-24, 1997.

*264.Gruessner RW, Sutherland DE, Troppmann C, Benedetti E, Hakim N, Dunn DL, Gruessner AC. The surgical risk of pancreas transplantation in the cyclosporine era: an overview. J Am Coll Surg 185:128-44, 1997.

*265.Klaerner HG, Uknis ME, Acton RD, Dahlberg PS, Carlone-Jambor C, Dunn DL. Candida albicans and Escherichia coli are synergistic pathogens during experimental microbial peritonitis. J Surg Res 70:161-5, 1997.

*266.Klaerner HG, Dahlberg PS, Acton RD, Battafarano RJ, Uknis ME, Johnston JW, Dunn DL. Immunization with antibodies that mimic LPS protects against gram negative bacterial sepsis. J Surg Res 70:249-54, 1997.

267.Casanova D, Sanjuan MV, Gruessner RW, Dunn DL, Sutherland DE. Infecciones en el trasplante de renon y pancreas. Enferm Infec Microbiol Clin 2:104-11, 1997.

268.Dunn DL. Presidential Address. Discovery. Surgery 122:123-8, 1997.

-27*269.Uknis ME, Wasiluk KR, Acton RD, Klaerner HG, Dahlberg PS, Ilyina E, Haseman JR, Gray BH,

Mayo KH, Dunn DL. Design of a potent novel endotoxin antagonist. Surgery 122:380-5, 1997. 270.Acton RD, Uknis ME, Klaerner HG, Dahlberg PS, Haseman JR, Gray BH, Dunn DL. A novel D-isomer

peptide inhibits gram-negative bacterial endotoxin. Surg Forum 68:65-7, 1997. *271.Matas AJ, Gillingham KJ, Dunn DL, Gruessner RWG, Payne WD, Sutherland DER, Najarian JS.

Risk factors for prolonged hospitalization after kidney transplants. Clin Transplantation 11:259-64, 1997.

*272.Gruessner RW, Sutherland DER, Najarian JS, Dunn DL, Gruessner AC. Solitary pancreas transplantation for nonuremic patients with labile insulin-dependent diabetes mellitus. Transplantation 64:1572-7, 1997.

*273.Humar A, Johnson EM, Payne WD, Dunn DL, Wrenshall LE, Najarian JS, Gruessner RWG, Matas AJ. The acutely ischemic extremity after kidney transplant: an approach to management. Surgery 123:344- 50,1998.

*274.Humar A, Johnson EM, Gillingham KJ, Sutherland DE, Payne WD, Dunn DL, Wrenshall LE, Najarian JS, Gruessner RW, Matas AJ. Venous thromboembolic complications after kidney and kidney-pancreas transplantation: a multivariate analysis. Transplantation 65:229-34, 1998.

*275.Troppmann C, Gruessner AC, Dunn DL, Sutherland DE, Gruessner RW. Surgical complications requiring early relaparotomy after pancreas transplantation: a multivariate risk factor and economic impact analysis of the cyclosporine era. Ann Surg 227:255-68, 1998.

*276.Matas AJ, McHugh L, Payne WD, Wrenshall LE, Dunn DL, Gruessner RWG, Sutherland DER, Najarian JS. Long-term quality of life after kidney and simultaneous pancreas-kidney transplantation. Clin Transplantation 12:233-42, 1998.

*277.Dahms RA, Johnson EM, Statz CL, Lee JT, Dunn DL, Beilman GJ. Third generation cephalosporin and vancomycin as risk factors for postoperative vancomycin-resistant Enterococcus infection. Arch Surg 133:1343-6, 1998.

*278.Humar A, Uknis M. Carlone-Jambor C, Gruessner RW, Dunn DL, Matas A. Cytomegalovirus disease recurrence after ga ncic lovir treatme nt in kidne y and kidne y-pa ncreas transplant recipients. Transplantation 67:94-7, 1999.

*279.Kellogg TA, Weiss CW, Johnston JW, Wasiluk KW, Dunn DL. Antiendotoxin agents share molecular homology within their lipopolysaccharide binding domains. J Surg Res 85:136-41, 1999.

280.Weiss III CA, Wasiluk KR, Kellogg TA, Gray BH, Mayo KH, Dunn DL. Designer peptides derived from bactericidal/permeability-increasing protein (BPI) recapitulate its endotoxin binding region. Surg Forum L :217-9, 1999.

281.Kellogg TA, Johnston JW, Weiss III CA, Wasiluk KR, Dunn DL. Use of genetic engineering to create a potent single chain Fv endotoxin antagonist. Surg Forum L:226-8, 1999.

*282.Humar A, Gillingham KJ, Payne WD, Dunn DL, Sutherland DER, Matas AJ. Association between cytomegalovirus disease and chronic rejection in kidney transplantation recipients. Transplantation 68:1879-83, 1999.

*283.Matas AJ, Humar A, Payne WD, Gillingham KJ, Dunn DL, Sutherland DER, Najarian JS. Decreased acute rejection in kidney transplant recipients is associated with decreased chronic rejection. Ann Surg 230:493-500, 1999.

*284.Weiss III CA, Statz CL, Dahms RA, Remucal MJ, Dunn DL, Beilman GJ. Six years of surgical wound infection surveillance at a tertiary care center: review of the microbiologic and epidemiological aspects of 20,007 wounds. Arch Surg 134:1041-8, 1999.

*285.West M, Pirenne J, Chavers B, Gillingham K, Sutherland DER, Dunn DL, Matas AJ. Clostridiurn difficile colitis after kidney and kidney-pancreas transplantation. Clin Transplantation 13:318-23, 1999.

-28*286.Nichols RL. Graham DR. Barriere SL. Rodgers A. Wilson SE. Zervos M. Dunn DL. Kreter B.

Treatment of hospitalized patients with complicated gram-positive skin and skin structure infections: two randomized, multicentre studies of quinupristin/dalfopristin versus cefazolin, oxacillin or vancomycin. Synercid Skin and Skin Structure Infection Group. J Antimicrobial Chemotherapy. 44:263-73, 1999.

*287.Matas AJ, Gillingham K, Humar A, Dunn DL, Sutherland DER, Najarian JS. Immunologic and nonimmunologic factor. Different risks for cadaver and living-donor transplantation. Transplantation 69:54-8, 2000.

288.Dunn DL. Diagnosis and treatment of opportunistic infections in immunocompromised surgical patients. Amer Surg 66:117-25, 2000.

*289.Matas AJ, Gillingham K, Payne WD, Humar A, Dunn DL, Sutherland DER, Najarian JS: Should I accept this kidney? Clin Transplantation 14:90-5, 2000.

*290.Grubbs BC, Statz CL, Johnson EM, Uknis ME, Lee JT, Dunn DL, Salvage therapy of open, infected surgical wounds: A retrospective review using Techni-Care. Surg Infections 1:109-114, 2000.

291.Nichols RL, Martone WJ, Barie PS, Bohnen JMA, Chambers HF, Christou NV, Condon RE, Dellinger EP, Dunn DL, Fabian TC, Fry DE, Ginzburg E, Gorbach SL, Hardin WD, Ledger WJ, Lee JT, Linden PK, Malangoni MA, Newell K, Rotstein OD, Wilson SE. Deliberations on the risks and antibiotic management of surgical infections. Surgery 128:S1-30, 2000.

*292.Weiss CA 3rd. Wasiluk KR. Kellogg TA. Dunn DL. Bactericidal and endotoxin neutralizing activity of a peptide derived from Limulus antilipopolysaccharide factor. Surgery 128:339-44, 2000.

293.Uknis ME, Dunn DL. Cytomegalovirus infection and disease after solid-organ transplantation: Epidemiology, prevention, and therapy. Transplantation Reviews 14:199-209, 2000.

294.Dunn DL. Prevention and treatment of multiple organ dysfunction syndrome: Lessons learned and future prospects. Surg Infections 1:227-37, 2000.

*295.Kellogg TA, Lazaron V, Wasiluk KR, Dunn DL. Binding specificity of polymyxin B, BPI, LALF, and anti-deep core/lipid A monoclonal antibody to lipopolysaccharide partial structures. Shock 15:124-9, 2001.

*296. Sutherland DER, Gruessner RWG, Dunn DL, Matas AJ, Humar A, Kandaswamy R, Mauer SM, Kennedy WR, Goetz FC, Robertson RP, Greussner AC, Najarian JS. Lessons learned from more than 1,000 pancreas transplants at a single institution. Ann Surg 233:463-501, 2001.

297.Kandaswamy R, Humar A, Payne WD, Dunn DL, Sutherland DE, Matas AJ. Risk factors for kidney transplant acute rejection: a multivariate analysis. Transplant Proc 33:1112, 2001.

298.Kandaswamy R, Gillingham K, Humar A, Payne WD, Dunn DL, Sutherland DE, Najarian JS, Matas AJ. Impact of HLA-ABDR match on chronic rejection in kidney transplants. Transplant Proc 33:1292, 2001.

*299.Matas AJ, Payne WD, Sutherland DER, Humar A, Gruessner RWG, Kandaswamy R, Dunn DL, Gillingham KJ, Najarian JS. 2,500 living donor kidney