department of chemical engineering - welcome! <...

DEPARTMENT OF CHEMICAL ENGINEERING

Department of Chemical Engineering | 3


Chemical engineering encompasses the translation of molecularinformation into discovery of new products and processes. Itinvolves molecular transformations—chemical, physical, andbiological—with multi-scale description from the submolecularto the macroscopic, and the analysis and synthesis of suchsystems. The chemical engineer is well prepared for a rewardingcareer in a strikingly diverse array of industries and professionalarenas. Whether these industries are at the cutting edge—e.g.,nanotechnology or biotechnology—or traditional, they dependon chemical engineers to make their products and processes areality. The effectiveness of chemical engineers in such a broadrange of areas begins with foundational knowledge in chemistry,biology, physics, and mathematics. From this foundation, chemicalengineers develop core expertise in engineering thermodynamics,transport processes, and chemical kinetics, creating a powerfuland widely applicable combination of molecular knowledge andengineering problem solving. To cope with complex, real-worldproblems, chemical engineers develop strong synthetic andanalytic skills. Through creative application of these chemicalengineering principles, chemical engineers create innovativesolutions to important industrial and societal problems in areassuch as development of clean energy sources, advancement oflife sciences, production of pharmaceuticals, sustainable systemsand responsible environmental stewardship, and discovery andproduction of new materials.

The Department of Chemical Engineering at MIT offers fourundergraduate programs. Course 10 leads to the Bachelor of Sciencein Chemical Engineering through a curriculum that prepares thegraduate for a wide range of career pursuits. Course 10-B leads tothe Bachelor of Science in Chemical-Biological Engineering, whichincludes the basic engineering core from the Course 10 degree andadds material in basic and applied biology. Course 10-ENG leads tothe Bachelor of Science in Engineering, a more flexible curriculumthat supplements a chemical engineering foundation with an areaof technical specialization. Course 10-C leads to the Bachelor ofScience without specification; this non-accredited degree requiresfewer chemical engineering subjects. Undergraduates have accessto graduate-level subjects in their upperclass years. Undergraduatestudents are also encouraged to participate in research throughthe Undergraduate Research Opportunities Program (UROP) (http://web.mit.edu/urop).

The department offers a broad selection of graduate subjectsand research topics leading to advanced degrees in chemicalengineering. Multidisciplinary approaches are highly valued,leading to strong ties with other MIT departments. In addition, thedepartment maintains alliances, arrangements, and connectionswith institutions and industries worldwide. Areas for specializationinclude, but are not limited to: biochemical engineering, biomedicalengineering, biotechnology, chemical catalysis, chemical processdevelopment, environmental engineering, fuels and energy, polymer

chemistry, surface and colloid chemistry, systems engineering,and transport processes. Additional information may be foundunder Graduate Education (http://catalog.mit.edu/mit/graduate-education) and on the department's website (http://web.mit.edu/cheme).

The School of Chemical Engineering Practice, leading to five-yearbachelor's and master's degrees, involves one term of work underthe direction of an Institute staff member resident at Practice Schoolsites. This program provides students with a unique opportunityto apply basic professional principles to the solution of practicalindustrial problems.

Undergraduate Study

The undergraduate curriculum in chemical engineering providesbasic studies in physics, biology, and mathematics, advancedsubjects in chemistry or biology, and a strong core of chemicalengineering. The four-year undergraduate programs providestudents with the fundamentals of the discipline and allow someroom for focus in subdisciplines or subjects that strengthen theirpreparation for advanced work.

In addition to science and engineering, students take an integratedsequence of subjects in the humanities and social sciences. Specificsubject selection allows students to meet individual areas ofinterest. The curriculum provides a sound preparation for jobsin industry or government, and for graduate work in chemicalengineering.

Chemical engineering also provides excellent preparation for careersin medicine and related fields of health science and technology. Thedepartment's strong emphasis on chemistry and biology providesexcellent preparation for medical school. Students interested inmedical school work with their faculty and premedical advisor tocreate the best program. A minor in biomedical engineering is alsoavailable.

Bachelor of Science in Chemical Engineering (Course 10)This degree (http://catalog.mit.edu/degree-charts/chemical-engineering-course-10) is intended for the student who seeks abroad education in the application of chemical engineering to avariety of specific areas, including energy and the environment,nanotechnology, polymers and colloids, surface science, catalysisand reaction engineering, systems and process design, andbiotechnology. The degree requirements include the corechemical engineering subjects with a chemistry emphasis, and theopportunity to add subjects in any of these application areas.

Course 10 is accredited by the Engineering AccreditationCommission of ABET (http://www.abet.org) as a chemicalengineering degree.


4 | Department of Chemical Engineering

Bachelor of Science in Chemical-Biological Engineering (Course10-B)This degree (http://catalog.mit.edu/degree-charts/chemical-biological-engineering-course-10-b) is intended for the student whois specifically interested in the application of chemical engineeringin the areas of biochemical and biomedical technologies. The degreerequirements include core chemical engineering subjects andadditional subjects in biological sciences and applied biology. Thisdegree is excellent preparation for students also considering thebiomedical engineering minor or medical school.

Course 10-B is accredited by the Engineering AccreditationCommission of ABET (http://www.abet.org) as a chemical andbiological engineering degree.

Students who decide early to major in either Course 10 or Course 10-B are encouraged to take subjects such as 5.111/5.112 Principles ofChemical Science, 5.12 Organic Chemistry I, and 7.01x IntroductoryBiology in their freshman year. Then 5.60 Thermodynamics andKinetics, 18.03 Differential Equations, 10.10 Introduction toChemical Engineering, 10.213 Chemical and Biological EngineeringThermodynamics, and 10.301 Fluid Mechanics may be taken in thesophomore year. The student is then well positioned for more in-depth and specialized subjects in the third and fourth years.

Some students may wish to defer choice of a major field or exercisemaximum freedom during the first two years. If the RestrictedElectives in Science and Technology (REST) Requirement subjectschosen in the second year include 18.03 Differential Equations andtwo subjects in the fields of fluid mechanics, thermodynamics,chemistry, biology, or chemical engineering, students can generallycomplete the requirements for a degree in chemical engineeringin two more years. Students are advised to discuss their proposedprogram with a Course 10 faculty advisor as soon as they becomeinterested in a degree in chemical engineering. Faculty advisors areassigned to students as soon as they declare their major and thenwork with the students through graduation. Further information maybe obtained from Dr. Barry S. Johnston.

Additional information is available on the Chemical EngineeringDepartment website (http://web.mit.edu/cheme). Undergraduatesare encouraged to take part in the research activities of thedepartment through the Undergraduate Research OpportunitiesProgram (UROP) (http://web.mit.edu/urop).

Bachelor of Science (Course 10-C)The curriculum (http://catalog.mit.edu/degree-charts/chemical-engineering-course-10-c) for students in Course 10-C involvesbasic subjects in chemistry and chemical engineering. Insteadof continuing in depth in these areas, students can add breadthby study in another field, such as another engineering discipline,biology, biomedical engineering, economics, or management.Course 10-C is attractive to students who wish to specialize in an

area such as those cited above while simultaneously gaining a broadexposure to the chemical engineering approach to solving problems.

Students planning to follow this curriculum should discuss theirinterests with their faculty advisor in the department at the time theydecide to enter the Course 10-C program, and submit to Dr. BarryS. Johnston in the department's Undergraduate Office a statementof goals and a coherent program of subjects no later than springterm of junior year. Please direct questions about this program to Dr.Johnston.

Bachelor of Science in Engineering as Recommended by theDepartment of Chemical Engineering (Course 10-ENG)The 10-ENG degree program (http://catalog.mit.edu/degree-charts/engineering-chemical-engineering-course-10-eng) is designed tooffer flexibility within the context of chemical engineering whileensuring significant engineering content, and is a complementto our chemical engineering degree programs 10 and 10-B. Thedegree is designed to enable students to pursue a deeper level ofunderstanding in a specific interdisciplinary field that is relevant tothe chemical engineering core discipline. The degree requirementsinclude all of the core chemical engineering coursework, plusa chosen set of three foundational concept subjects and foursubjects with engineering content that make up a comprehensiveconcentration specific to the interdisciplinary area selected by thestudent. The concentrations have been selected by the Departmentof Chemical Engineering to represent new and developing cross-disciplinary areas that benefit from a strong foundation inengineering within the chemical engineering context. Details of theconcentrations are available from the Chemical Engineering StudentOffice and the department's website (http://web.mit.edu/cheme/academics/undergrad).

The foundational concept component of the flexible engineeringdegree consist of basic science and engineering subjects thathelp lay the groundwork for the chosen concentration. Threesubjects must be selected from a list of potential topics. One ofthe foundational concept subjects must be a chemical engineeringCI-M subject, and one must be a laboratory subject that satisfiesthe Institute Laboratory Requirement. The subjects should beselected with the assistance of a 10-ENG degree advisor from theChemical Engineering Department so as to be consistent with thedegree requirements of the program and the General InstituteRequirements. Several of these subjects can satisfy the program'sCI-M requirement.

The flexible engineering concentration consists of four subjects thatare selected by the student from a suggested subject list providedfor each 10-ENG concentration; the student also may proposesubjects that fit the theme of the chosen concentration. These listsare included in the concentration descriptions provided on thedepartment's website and at the Chemical Engineering StudentOffice. Students work with their 10-ENG advisors to propose a 10-



ENG degree program, which must then be approved by the ChemicalEngineering Undergraduate Committee.

The flexible engineering degree major capstone experience consistsof 12 units and/or a senior-level project. Alternatively, the studentmay choose to complete a senior thesis in a topic area relevant tothe concentration. Senior-level projects or senior thesis projectsare specifically designed to integrate engineering principlesinto specific applications or problems and are not standardUROP projects; such projects require the preliminary approval of thedepartment's undergraduate officer.

Course 10-ENG is accredited by the Engineering AccreditationCommission of ABET (http://www.abet.org) as an engineeringdegree.

Five-Year Programs and Joint ProgramsIn addition to offering separate programs leading to the Bachelorof Science and Master of Science in Chemical Engineering, thedepartment offers a program leading to the simultaneous award ofboth degrees at the end of five years. A detailed description of thisprogram is available from the Graduate Student Office. Studentsin the five-year program normally enroll in the School of ChemicalEngineering Practice.

For chemical engineering students interested in nuclearapplications, the Department of Chemical Engineering and theDepartment of Nuclear Engineering offer a five-year program leadingto the joint Bachelor of Science in Chemical Engineering and Masterof Science in Nuclear Engineering. Such programs are approvedon an individual basis between the registration officers of the twodepartments.

InquiriesAdditional information concerning undergraduate academic andresearch programs may be obtained by writing to Dr. Barry S.Johnston ([email protected]), undergraduate officer, Departmentof Chemical Engineering, Room 66-368, 617-258-7141, fax617-258-0546. For information regarding admissions and financialaid, contact the Admissions Office, Room 3-108, 617-253-4791.

Graduate Study

Graduate study provides both rigorous training in the fundamentalcore discipline of chemical engineering and the opportunity to focuson specific subdisciplines. In addition to completing the four coresubject requirements in thermodynamics, reaction engineering,numerical methods, and transport phenomena, students select aresearch advisor and area for specialization, some of which arediscussed below.

Thermodynamics and Molecular Computation. Thermodynamicsis a cornerstone of chemical engineering. Processes as diverse aschemical production, bioreaction, creation of advanced materials,protein separation, and environmental treatment are governed by

thermodynamics. The classical concepts of equilibrium, reversibility,energy, and entropy are basic to the analysis and design ofthese processes. The extension of classical thermodynamics tomolecular scales by use of statistical mechanics has made molecularsimulation an increasingly valuable tool for the chemical engineer.Prediction of macroscopic behavior from molecular computations isbecoming ever more feasible. This venerable field continues to yieldfruitful areas of inquiry.

Opportunities in the department for graduate study in this fieldinclude predicting properties of materials and polymers frommolecular structure, applying quantum mechanics to catalystdesign, supercritical fluid processing, the behavior of complex fluidswith environmental and biomedical applications, phase equilibriumwith simple and complex molecular species, immunology, proteinstabilization, nucleation and crystallization of polymer andpharmaceuticals, and many other areas of classical and statisticalthermodynamics.

Transport Processes. A fluid deforming and flowing as forces areimposed on it, its temperature varying as heat is transferred throughit, the interdiffusion of its distinct molecular species—these areexamples of the processes of transport. These transport processesgovern the rates at which velocity, temperature, and compositionvary in a fluid; chemical engineers study transport to be able todescribe, predict, and manage these changes. Research includesexperimental testing and analytical and computational modeling;its applications range among an enormous variety of mechanical,chemical, and biological processes.

Current work includes the study of polymer molecular theoryand polymer processing, transport and separations inmagnetorheological fluids, membrane separations, diffusion incomplex fluids, defect formation and evolution in near-crystallinematerials, microfluidics, fluid instability, transport in living tissue,numerical solution of field equations, and many other areas oftransport phenomena.

Catalysis and Chemical Reaction Engineering. A simple chemicalreaction—the rearrangement of electrons and bonding partners—occurs between two small molecules. From understanding thekinetics of the reaction, and the equilibrium extent to which itcan proceed, come applications: the network of reactions duringcombustion, the chain reactions that form polymers, the multiplesteps in the synthesis of a complex pharmaceutical molecule, thespecialized reactions of proteins and metabolism. Chemical kineticsis the chemical engineer's tool for understanding chemical change.

A catalyst influences the reaction rate. Catalysts are sought forincreasing production, improving the reaction conditions, andemphasizing a desired product among several possibilities. Thechallenge is to design the catalyst, to increase its effectiveness andstability, and to create methods to manufacture it.

A chemical reactor should produce a desired product reliably,safely, and economically. In designing a reactor, the chemical



engineer must consider how the chemical kinetics, often modifiedby catalysis, interacts with the transport phenomena in flowingmaterials. New microreactor designs are expanding the concept ofwhat a reactor may do, how reactions may be conducted, and what isrequired to scale a process from laboratory to production.

Research is being conducted in the department at the forefront ofcatalyst design, complex chemical synthesis, bioreactor design,surface- and gas-phase chemistry, miniaturization of reactors,mathematical modeling of chemical reaction networks, and manyother areas of chemical reaction engineering. Applications includethe manufacturing of chemicals, refining of fuels for transportationand power, and microreactors for highly reactive or potentiallyhazardous materials.

Polymers. Wondrous materials found in nature and now synthesizedin enormous quantity and variety, polymers find an ever-increasinguse in manufactured products. Polymers are versatile becausetheir properties are so wide-ranging, as is evident even in theconceptually simple polymers made from a single molecular species.The versatility becomes more profound in the copolymers madefrom multiple precursors, and the polymers compounded withfiller materials. Research in polymers encompasses the chemicalreactions of their formation, methods of processing them intoproducts, means of modifying their physical properties, and therelationship between the properties and the underlying molecular-and solid-phase structure.

Graduate research opportunities in the department include studiesof polymerization kinetics, non-Newtonian rheology, polymer thinfilms and interfaces, block copolymers, liquid crystalline polymers,nanocomposites and nanofibers, self-assembly and patterning, andmany other areas of polymer science and engineering. In additionto a program in graduate study in polymers within the department,the interdisciplinary Program in Polymers and Soft Matter (PPSM)provides a community for researchers in the polymer field and offersa program of study that focuses on the interdisciplinary nature ofpolymer science and engineering.

Materials. The inorganic compounds found in nature are the basisfor new materials made by modifying molecular composition (suchas purifying silicon and doping it with selected impurities) andstructure (such as control of pore and grain size). These materialshave electronic, mechanical, and optical properties that supporta variety of novel technologies. Other materials are applied ascoatings—thin films that create a functional surface. Still othermaterials have biological applications, such as diagnostic sensorsthat are compatible with living tissue, barriers that control therelease of pharmaceutical molecules, and scaffolds for tissuerepair. A new generation of biomaterials is being derived frombiological molecules. Research in materials is wide-ranging andhighly interdisciplinary, both fundamental and applied. In thedepartment, materials research includes studies in plasma etching,thin-film chemical vapor deposition, crystal growth, nano-crystallinestructure, molecular simulation, scaffolds for bone and soft tissue

regeneration, biocompatible polymers, and many other areas ofmaterials engineering.

Surfaces and Nanostructures. In many arrangements of matter, theinterfaces between phases—more than their bulk compositions—arecritical to the material structure and behavior. The surfaces of solidsoffer a platform for functional coating; coatings may be depositedfrom vapor, applied as a volatile liquid, or assembled from solutiononto the solid, in a pattern determined by the molecular properties.This self-assembly tendency may be exploited to arrange desiredpatterns that have operational properties. Interfacial effects arealso responsible for stable dispersions of immiscible phases,leading to fluids with complex microstructure. Other structuredfluids arise from large molecules whose orientation in the solventis constrained by molecular size and properties. In solids, tightcontrol of pore size, grain size, chemical composition, and crystalstructure offer a striking range of catalytic, mechanical, andelectromagnetic properties. The understanding of gas-solid kineticsis crucial to the study of heterogeneous catalysis and integratedcircuit fabrication. Structure is the basis for function, and bymanipulating tiny length scales, the resulting nanostructure makesavailable new capabilities, and thus new technologies and products.Graduate study in surfaces and nanostructures may include studiesof colloids, emulsions, surfactants, and other structured fluidswith biological, medical, or environmental applications. It alsoencompasses thin films, liquid crystals, sol-gel processing, controlof pharmaceutical morphology, nanostructured materials, carbonnanotubes, surface chemistry, surface patterning, and many otherareas of nanotechnology and surface science.

Biological Engineering. Chemical engineering thermodynamics,transport, and chemical kinetics, so useful for manufacturingprocesses, are fruitful tools for exploring biological systems aswell. Biological engineering research may be directed at molecular-level processes, the cell, tissues, the organism, and large-scalemanufacturing in biotech processes. It may be applied to producingspecialized proteins, genetic modification of cells, transportof nutrients and wastes in tissue, therapeutic methods of drugdelivery, tissue repair and generation, purification of productmolecules, and control strategies for complex bioproductionplants. Its methods include analytical chemistry and biochemistrytechniques, bioinformatic processing of data, and computationalsolution of chemical reaction and transport models. Biologicalengineering is an extraordinarily rich area for chemical engineers,and its consequences—theoretical, medical, commercial—will be far-reaching.

Opportunities in the department for graduate study in biologicalengineering include manipulation and purification of proteins andother biomolecules, research into metabolic processes, tissueregeneration, gene regulation, bioprocesses, bioinformatics, drugdelivery, and biomaterials, to name a few. Both experimental andcomputational methods are used, including statistical mechanicsand systems theory. Chemical engineering faculty are also involvedin the Center for Biomedical Engineering, created to enhance



interdisciplinary research and education at the intersection ofengineering, molecular and cell biology, and medicine. The Novartis-MIT Center for Continuous Manufacturing, another center of researchactivity involving chemical engineers, promises to revolutionize thechemical processing of pharmaceuticals.

Energy and Environmental Engineering. Making energy available tosociety requires finding and producing a range of fuels, improvingthe efficiency of energy use under the ultimate limits imposedby thermodynamics, and reducing the effects of these processeson the environment. The widespread use of fossil fuels increasesthe amount of carbon dioxide in the atmosphere, leading toconcerns about global warming. Other sustainability indicatorsalso suggest that we now need to transform our energy systemto a more efficient, lower-carbon future. This transformationprovides many opportunities for chemical engineers to evaluateand explore other energy supply options such as renewable energyfrom solar, biomass, and geothermal resources, nonconventionalfuels from heavy oils, tar sands, natural gas hydrates, and oil shales.Developing technologies for transporting and storing thermal andelectrical energy over a range of scales are also of interest.

Further environmental distress can result from manufacturingprocesses and society's use of the manufactured products. Thetraditional response of treating process wastes is still useful, butthere is growing emphasis on designing new processes to produceless waste. This might be done by improving catalysts to decreaseunwanted by-products, finding alternatives to volatile solvents, anddeveloping more effective separation processes. Chemical engineersare at work in these areas, and in developing alternative energysources and assessing the effects of pollutants on human health.

In the department, students will find expertise in combustion,chemical reaction networks, renewable energy and upgrading ofnonconventional fuels, carbon dioxide capture and sequestration,water purification and catalytic treatment of pollutants, global airpollution modeling, design of novel energy conversion processes,energy supply chains, and many other areas of energy andenvironmental engineering. Faculty in the department are activelyinvolved in the MIT Energy Initiative.

Systems Design and Simulation. From early in the development ofchemical engineering, processes were represented as combinationsof unit operations. This concept was useful in analyzing processes,as well as providing a library of building blocks for creating newprocesses. Process and product design are imaginative activities,an artful blend of intuition and analysis. Design is aided bymathematical tools that simulate the behavior of the process orproduct and seek optimum performance. Effective use of simulationand optimization tools allows unexpected pathways to be explored,dangerous operating regions to be identified, and transient andaccident conditions to be tested. Process and product systemsengineering brings it all together, placing the technical featuresof a process or product in the context of operations, economics,and business. The end result is improved economy, reliability,

and safety. Methodologies for process and product modeling andsimulation, computer-aided engineering, operations research,optimization theory and algorithms, process and product designstrategy, treatment of uncertainty, multiscale systems engineering,and many other areas of systems engineering are being developedin the Department of Chemical Engineering. Such research leads tonew prototypes for process systems, design of new molecules withdesired properties, and processes with better operability, control,safety, and environmental performance.

School of Chemical Engineering PracticeSince 1916, the David H. Koch School of Chemical EngineeringPractice has been a major feature of the graduate education in thedepartment. In this unique program, students receive intensiveinstruction to broaden their education in the technical aspectsof the profession, and also in communication skills and humanrelations, which are frequently decisive factors in the success ofan engineering enterprise. The Practice School program stressesproblem solving in an engineering internship format, where studentsundertake projects at industrial sites under the direct supervisionof resident MIT faculty. Credit is granted for participation in thePractice School in lieu of preparing a master's thesis.

The operation of the Practice School is similar to that of a smallconsulting company. The resident staff work closely with thetechnical personnel of the host companies in identifying projectassignments with significant educational merit, and with solutionsthat make important contributions to the operation of the company.

During Practice School, students work on three or four differentprojects. Groups and designated group leaders change from oneproject to another, giving every individual an opportunity to be agroup leader at least once.

Students in the Practice School program are required to demonstrateproficiency, or take one graduate subject, in each of the followingareas: thermodynamics, heat and mass transfer, applied processchemistry, kinetics and reactor design, systems engineering, andapplied mathematics.

Master of Science in Chemical EngineeringPrograms for the Master of Science in Chemical Engineering usuallyare arranged as a continuation of undergraduate professionaltraining, but at a greater level of depth and maturity. The generalrequirements for a master's program are given in the sectionon Graduate Education (http://catalog.mit.edu/mit/graduate-education). To complete the requirement of at least 66 subjectunits, of which 42 units must be graduate subjects, together with anacceptable thesis, generally takes four terms.

Master of Science in Chemical Engineering PracticeThe unit requirements for the Master of Science in ChemicalEngineering Practice (Course 10-A) are the same as those for the



Master of Science in Chemical Engineering, except that 48 units ofPractice School experience replace the master's thesis.

In some cases, Bachelor of Science graduates of this departmentcan meet the requirements for the Master of Science in ChemicalEngineering Practice (Course 10-A) in two terms. Beginning inSeptember following graduation, students complete the requiredcoursework at the Institute. The spring semester is spent at thePractice School field stations. Careful planning of the senior yearschedule is important.

For students who have graduated in chemical engineering from otherinstitutions, the usual program of study for the Master of Sciencein Chemical Engineering Practice involves two terms at the Institutefollowed by field station work in the Practice School. Graduates inchemistry from other institutions normally require an additionalterm.

Doctor of Science or Doctor of PhilosophyDoctoral candidates are required to pass a written generalexamination early in their program of study. Given in January andMay, the written examination is usually taken at the end of thefirst term in residence as a graduate student. There is also an oralgeneral examination, which consists of the presentation of a thesisproposal to a faculty committee; this is normally done during thesecond year of residence. Completing a master's degree is nota prerequisite for entering the doctoral program or obtaining adoctoral degree.

The requirements for the doctoral degree include a program ofadvanced study, a minor program, a biology requirement, and athesis. The program of advanced study and research is normallycarried out in one of the fields of chemical engineering under thesupervision of one or more faculty members in the Departmentof Chemical Engineering. A thesis committee of selected facultymonitors the doctoral program of each candidate.

Doctor of Philosophy in Chemical Engineering PracticeThis degree program provides educational experience that combinesadvanced work in manufacturing, independent research, andmanagement. The program is built on the outstanding researchprograms within the department, the unique resources of the DavidH. Koch School of Chemical Engineering Practice, and the world-class resources of the Sloan School of Management. Students areprepared for a rapid launch into positions of leadership in industryand provided with a foundation for completion of an MBA degree.

The program consists of three major parts: the first year is devotedto coursework and the Practice School, the two middle years aredevoted to research, and the final year is completed in the SloanSchool of Management. In addition, an integrative project combinesthe research and management portions of the program.

Students in the PhD in Chemical Engineering Practice (PhDCEP)program must pass the department's written and oral examinations.

The progress of their research is monitored by a faculty committee,and the final thesis document is defended in a public forum. Thenormal completion time should be four calendar years for thePhDCEP program.

Interdisciplinary Programs

Computational Science and EngineeringThe Computational Science and Engineering (CSE) (http://computationalengineering.mit.edu/education) program allowsstudents to specialize at the doctoral level in a computation-relatedfield of their choice through focused coursework and a doctoralthesis through a number of participating host departments. The CSEprogram is administered jointly by the Center for ComputationalEngineering (CCE) and the host departments, with the emphasisof thesis research activities being the development of newcomputational methods and/or the innovative application ofcomputational techniques to important problems in engineeringand science. For more information, see the full program description(http://catalog.mit.edu/interdisciplinary/graduate-programs/computational-science-engineering) under InterdisciplinaryGraduate Programs.

Leaders for Global OperationsThe 24-month Leaders for Global Operations (LGO) (http://lgo.mit.edu) program combines graduate degrees in engineering andmanagement for those with previous postgraduate work experienceand strong undergraduate degrees in a technical field. During thetwo-year program, students complete a six-month internship at oneof LGO's partner companies, where they conduct research that formsthe basis of a dual-degree thesis. Students finish the program withtwo MIT degrees: an MBA (or SM in management) and an SM fromone of six engineering programs, some of which have optional orrequired LGO tracks. After graduation, alumni take on leadershiproles at top global manufacturing and operations companies.

MicrobiologyThe MIT Microbiology Graduate PhD Program (http://catalog.mit.edu/interdisciplinary/graduate-programs/microbiology)is an interdepartmental, interdisciplinary program that providesstudents broad exposure to underlying elements of modernmicrobiological research and engineering, and depth in specificareas of microbiology during the student‘s thesis work. MIThas a long-standing tradition of excellence in microbiologicalresearch; currently, more than 50 faculty from different departmentsstudy or use microbes in significant ways in their research. Theprogram integrates educational resources across the participatingdepartments to build connections among faculty with sharedinterests from different units and to build an educational communityfor training students in the study of microbial systems. Studentsapply to the Microbiology program and conduct research in thelabs of faculty in one of the participating departments: Biology;Biological Engineering; Chemical Engineering; Chemistry; Civiland Environmental Engineering; Earth, Atmospheric and Planetary



Sciences; Electrical Engineering and Computer Science; MaterialsSciences and Engineering; and Physics. Graduates of this programwill be prepared to enter a range of fields in microbial science andengineering, and will have excellent career options in academic,industrial, and government settings.

Polymers and Soft MatterThe Program in Polymers and Soft Matter (PPSM) (http://polymerscience.mit.edu) offers students from participatingdepartments an interdisciplinary core curriculum in polymer scienceand engineering, exposure to the broader polymer communitythrough seminars, contact with visitors from industry and academia,and interdepartmental collaboration while working towards a PhD orScD degree.

Research opportunities include functional polymers, controlleddrug delivery, nanostructured polymers, polymers at interfaces,biomaterials, molecular modeling, polymer synthesis, biomimeticmaterials, polymer mechanics and rheology, self-assembly, andpolymers in energy. The program is described in more detail underInterdisciplinary Graduate Programs (http://catalog.mit.edu/interdisciplinary/graduate-programs/polymers-soft-matter).

Financial SupportThe department has a wide variety of financial support options forgraduate students, including teaching and research assistantships,fellowships, and loans. Information about financial assistancemay be obtained by writing to the Graduate Student Office, butconsideration for awards cannot be given before admissionsdecisions have been made.

InquiriesFor additional information concerning graduate programs,admissions, financial aid, and assistantships, contact the GraduateStudent Office ([email protected]), Department of ChemicalEngineering, Room 66-366, 617-253-4579.

Faculty and Teaching Staff

Paula T. Hammond, PhDDavid H. Koch Professor of EngineeringProfessor of Chemical EngineeringHead, Department of Chemical Engineering

Martin Z. Bazant, PhDProfessor of Chemical EngineeringProfessor of MathematicsExecutive Officer, Department of Chemical Engineering

ProfessorsRobert C. Armstrong, PhDChevron ProfessorProfessor of Chemical Engineering

Paul I. Barton, PhDLammot du Pont Professor of Chemical Engineering(On leave)

Daniel Blankschtein, PhDHerman P. Meissner (1929) Professor of Chemical Engineering

Richard D. Braatz, PhDEdwin R. Gilliland ProfessorProfessor of Chemical Engineering

Arup K. Chakraborty, PhDRobert T. Haslam (1911) ProfessorDirector, Institute for Medical Engineering and ScienceProfessor of Chemical EngineeringProfessor of Biological EngineeringProfessor of ChemistryProfessor of Physics

Robert E. Cohen, PhDRaymond A. and Helen E. St. Laurent Professor Post-Tenure of

Chemical Engineering

Clark K. Colton, PhDProfessor of Chemical Engineering

Charles L. Cooney, PhDRobert T. Haslam (1911) Professor Post-Tenure of Chemical

Engineering

William M. Deen, PhDCarbon P. Dubbs Professor Post-Tenure of Chemical Engineering

Patrick S. Doyle, PhDRobert T. Haslam (1911) Professor of Chemical Engineering

Karen K. Gleason, PhDAlexander and I. Michael Kasser (1960) ProfessorProfessor of Chemical EngineeringAssociate Provost

William H. Green Jr, PhDHoyt Hottel Professor of Chemical Engineering

T. Alan Hatton, PhDRalph Landau (1941) ProfessorProfessor of Chemical Engineering

Klavs F. Jensen, PhDWarren K. Lewis Professor of Chemical EngineeringProfessor of Materials Science and Engineering



Robert Langer, ScDDavid H. Koch (1962) Institute ProfessorProfessor of Chemical EngineeringProfessor of Mechanical EngineeringProfessor of Biological EngineeringMember, Health Sciences and Technology Faculty

Douglas A. Lauffenburger, PhDFord Foundation ProfessorHead, Department of Biological EngineeringProfessor of Biological EngineeringProfessor of Chemical EngineeringProfessor of Biology

Kristala L. Jones Prather, PhDProfessor of Chemical Engineering

Gregory C. Rutledge, PhDLammot du Pont Professor of Chemical Engineering

George Stephanopoulos, PhDArthur Dehon Little ProfessorProfessor of Chemical Engineering

Gregory Stephanopoulos, PhDWillard Henry Dow Professor of Chemical Engineering

Michael S. Strano, PhDCarbon P. Dubbs Professor of Chemical Engineering

Bernhardt L. Trout, PhDRaymond F. Baddour ProfessorProfessor of Chemical Engineering

Daniel I. Wang, PhDInstitute ProfessorProfessor of Chemical Engineering

Karl Dane Wittrup, PhDCarbon P. Dubbs Professor of Chemical EngineeringProfessor of Biological Engineering

Associate ProfessorsDaniel Griffith Anderson, PhDAssociate Professor of Chemical EngineeringCore Faculty, Institute for Medical Engineering and Science

Jesse Kroll, PhDAssociate Professor of Civil and Environmental EngineeringAssociate Professor of Chemical Engineering

J. Christopher Love, PhDAssociate Professor of Chemical Engineering

Bradley D. Olsen, PhDPaul M. Cook Career Development ProfessorAssociate Professor of Chemical Engineering

Yuriy Roman, PhDAssociate Professor of Chemical Engineering

Hadley Sikes, PhDAssociate Professor of Chemical Engineering

William A. Tisdale, PhDAssociate Professor of Chemical Engineering

Preetinder S. Virk, ScDAssociate Professor of Chemical Engineering

Assistant ProfessorsFikile Richard Brushett, PhDRaymond (1921) and Helen St. Laurent Career Development ProfessorAssistant Professor of Chemical Engineering

Kwanghun Chung, PhDSamuel A. Goldblith Professor of Applied BiologyAssistant Professor of Chemical EngineeringAssistant Professor of Brain and Cognitive SciencesCore Faculty, Institute for Medical Engineering and Science

Heather J. Kulik, PhDJoseph R. Mares (1924) Career Development ProfessorAssistant Professor of Chemical Engineering

Karthish Manthiram, PhDAssistant Professor of Chemical Engineering

James W. Swan, PhDTexaco-Mangelsdorf Career Development ProfessorAssistant Professor of Chemical Engineering

Professors of the PracticeAllan S. Myerson, PhDProfessor of the Practice of Chemical Engineering

Visiting Associate ProfessorsJong Min Lee, PhDVisiting Associate Professor of Chemical Engineering

Visiting Assistant ProfessorsNarendra Maheshri, PhDVisiting Assistant Professor of Chemical Engineering

Senior LecturersRobert J. Fisher, PhDSenior Lecturer in Chemical Engineering

Robert T. Hanlon, ScDSenior Lecturer in Chemical Engineering

Barry S. Johnston, PhDSenior Lecturer in Chemical Engineering



LecturersThomas J. Blacklock, PhDLecturer in Chemical Engineering

Bonnie D. Burrell van Stephoudt, PhDLecturer in Chemical Engineering

Daniel Adam Doneson, PhDLecturer in Chemical Engineering

Alberto Ghibellini, PhDLecturer in Chemical Engineering

Kathryn Elizabeth Hansen, PhDLecturer in Chemical Engineering

Douglas Harrison, PhDLecturer in Chemical Engineering

Luis Perez-Breva, PhDLecturer in Chemical Engineering

Brian E. Stutts, PhDLecturer in Chemical Engineering

Research Staff

Research EngineersLorenz Baumgartner, PhDResearch Engineer in Chemical Engineering

Michael Bellucci, PhDResearch Engineer in Chemical Engineering

Jean-François P. Hamel, PhDResearch Engineer in Chemical Engineering

Takuya Harada, PhDResearch Engineer in Chemical Engineering

Research ScientistsLev E. Bromberg, PhDResearch Scientist in Chemical Engineering

Devin Currie, PhDResearch Scientist in Chemical Engineering

Liang Su, PhDResearch Scientist in Chemical Engineering

Professors Emeriti

János M. Beér, ScD, PhDProfessor Emeritus of Chemical Engineering

Robert A. Brown, PhDProfessor Emeritus of Chemical Engineering

Lawrence B. Evans, PhDProfessor Emeritus of Chemical Engineering

Gregory J. McRae, PhDProfessor Emeritus of Chemical Engineering

Edward W. Merrill, ScDProfessor Emeritus of Chemical Engineering

Herbert Harold Sawin, PhDProfessor Emeritus of Chemical EngineeringProfessor Emeritus of Electrical Engineering

Kenneth A. Smith, PhDProfessor Emeritus of Chemical Engineering

Jefferson W. Tester, PhDProfessor Emeritus of Chemical Engineering

10.00 Molecule BuildersPrereq: Chemistry (GIR), Physics I (GIR)U (Spring)1-6-2 units

Project-based introduction to the applications of engineeringdesign at the molecular level. Working in teams, students completean open-ended design project that focuses on a topic such asreactor or biomolecular engineering, chemical process design,materials and polymers, or energy. Provides students practicalexposure to the field of chemical engineering as well as potentialopportunities to continue their project designs in national/international competitions.Limited to 36; preference to first yearstudents.B. D. Olsen



10.01 Ethics for EngineersEngineering School-Wide Elective Subject.Offered under: 1.082, 2.900, 6.904, 10.01, 22.014Subject meets with 6.9041Prereq: NoneU (Fall, Spring)2-0-4 units

Integrates classical readings that provide an overview of ethics witha survey of case studies that focus on ethical problems arising in thepractice of engineering. Readings taken from a variety of sources,such as Aristotle, Machiavelli, Bacon, Hobbes, Locke, the FoundingFathers, and the Bible. Case studies include written analysesand films that address engineering disasters, biotechnology,court cases, ethical codes, and the ultimate scope and aims ofengineering. Students taking independent inquiry version 6.9041expand the scope of their term project.D. Doneson, B. L. Trout

10.02 Foundations of Entrepreneurship for EngineersPrereq: NoneU (Spring)3-0-9 units

Studies economic and leadership foundations of entrepreneurshipas they relate to engineering. Case studies illustrate major impactsof engineering on the world and examine the leaders responsible forsuch impacts. Authors include Franklin, Keynes, Leonardo, Lincoln,Locke, Machiavelli, Marx, Schmidt, Schumpeter, Smith, Thiel, andTocqueville. Discusses topics such as the difference between anentrepreneur and a manager, the entrepreneur as founder, andcharacteristics of principled entrepreneurship.D. Doneson, B. L. Trout

10.03[J] Advances in BiomanufacturingSame subject as 7.458[J]Subject meets with 7.548[J], 10.53[J]Prereq: NoneU (Spring; second half of term)1-0-2 units

Seminar examines how biopharmaceuticals, an increasinglyimportant class of pharmaceuticals, are manufactured. Topicsrange from fundamental bioprocesses to new technologies tothe economics of biomanufacturing. Also covers the impact ofglobalization on regulation and quality approaches as well assupply chain integrity. Students taking graduate version completeadditional assignments.J. C. Love, A. Sinskey, S. Springs

10.04 A Philosophical History of EnergyPrereq: NoneU (Spring)3-0-9 units

Philosophic and historical approach to conceptions of energythrough the 19th century. Relation of long standing scientific andphilosophic problems in the field of energy to 21st-century debates.Topics include the development of thermodynamics and kinetictheories, the foundation of the scientific project, the classical viewof energy, and the harnessing of nature. Authors include Bacon,Boltzmann, Carnot, Compte, Descartes, Gibbs, Plato, Aristotle,Leibniz, Kant, Hegel, Mill, Peirce, Whitehead, and Maxwell. Key textsand controversies form topics of weekly writing assignments andterm papers.B. L. Trout, A. Schulman

10.05 Foundational Analyses of Problems in Energy and theEnvironmentPrereq: NoneU (Fall, Spring)3-0-9 units

Investigates key texts and papers on the foundational thoughtof current issues in energy and environmental science. Builds anunderstanding of key debates (scientific, ethical, and political). Aimsto inform solutions to key problems related to procurement of energyand environmental degradation. Topics address alternative energytechnologies and fossil fuel utilization and emissions, especiallycarbon dioxide, carbon dioxide sequestration, and geoengineering.Foundational readings from Homer and Greek playwrights, Aristotle,Genesis, Bacon, Locke, Rousseau, Coleridge, Carnot, Clausius, Marx,Heidegger, Carson, Gore, Singer, and Brundtland. Assignmentsinclude weekly analyses of readings, videos and related engineeringcalculations in addition to a final project.Limited to 18.B. L. Trout



10.06 Advanced Topics in Ethics for Engineers (New)Prereq: 10.01, 10.05, permission of instructorU (Fall, Spring)2-0-4 unitsCan be repeated for credit.

In-depth study of varying advanced topics in ethics for engineers.Focuses on foundational works and their significance for the choicesthat engineers make, both as students and as practicing engineers.Each semester, different works and topics, based on current andperennial issues in ethics and engineering, will be chosen in orderto explore facets of the extremely complex and varied subject ofthe place of engineering for the individual and society. Examplesof topics include genetic engineering and what it means to behuman, artificial intelligence and thought, the scope and limits ofengineering, and engineering and freedom. May be repeated forcredit with permission of instructor.Limited to 20.B. L. Trout, D. Doneson

10.10 Introduction to Chemical EngineeringPrereq: Chemistry (GIR), Physics I (GIR), Calculus I (GIR)U (Fall, Spring)4-0-8 units

The diverse applications of chemical engineering are exploredthrough example problems. Solutions require application offundamental concepts of mass and energy conservation to batch andcontinuous systems, involving chemical and biological processes.Computer skills and the elements of engineering design are taughtin the context of these example problems. The objective is toacquaint the student with the field of chemical engineering and toenable use of computer methods to solve chemical and biologicalengineering problems.B. S. Johnston, K. L. J. Prather

10.213 Chemical and Biological Engineering ThermodynamicsPrereq: 5.60, 10.10U (Spring)4-0-8 units

Thermodynamics of multicomponent, multiphase chemical andbiological systems. Applications of first, second, and third lawsof thermodynamics to open and closed systems. Properties ofmixtures, including colligative properties, chemical reactionequilibrium, and phase equilibrium; non-ideal solutions; powercycles; refrigeration; separation systems.K. K. Gleason, H. D. Sikes

10.22 Molecular EngineeringPrereq: 5.60, 10.213U (Spring)3-0-9 units

Introduces molecular concepts in relation to engineeringthermodynamics. Includes topics in statistical mechanics, moleculardescription of gases and liquids, property estimation, descriptionof equilibrium and dynamic properties of fluids from molecularprinciples, and kinetics of activated processes. Also covers somebasic aspects of molecular simulation and applications in systems ofengineering interest.G. C. Rutledge, P. S. Doyle

10.25 Industrial Chemistry and Chemical Process PathwaysPrereq: Chemistry (GIR), 10.213, 10.37G (Fall)Not offered regularly; consult department3-0-6 units

Chemical and engineering principles involved in creation andoperation of viable industrial processes. Topics: analysis of processchemistry by p-pathways (i.e., radical, ionic, and pericyclic reactionsof organic syntheses) and d-pathways (i.e., catalysis by transition-metal complexes). Use of reaction mechanisms for inference of co-product formation, kinetics, and equilibria: process synthesis logicrelated to reaction selectivity, recycle, separations. Illustrationsdrawn from current and contemplated commercial practice.P. S. Virk

10.26 Chemical Engineering Projects LaboratorySubject meets with 10.27, 10.29Prereq: 2.671, 3.014, 5.310, 7.02[J], 12.335, or 1.106 and 1.107;10.302; or permission of instructorU (Spring)3-8-4 units

Projects in applied chemical engineering research. Students workin teams on one project for the term. Projects often suggested bylocal industry. Includes training in research planning and projectmanagement, execution of experimental work, data analysis, oralpresentation skills and individual report writing, and team-building.C. K. Colton, B. S. Johnston, B. D. Burrell, G. C. Rutledge



10.27 Energy Engineering Projects LaboratorySubject meets with 10.26, 10.29Prereq: 2.671, 3.014, 5.310, 7.02[J], 12.335, or 1.106 and 1.107;10.302; or permission of instructorU (Spring)3-8-4 units

Projects in applied energy engineering research. Students workin teams on one project for the term. Projects often suggested bylocal industry. Includes training in research planning and projectmanagement, execution of experimental work, data analysis,oral presentation skills and technical report writing, and team-building. Projects consider social science issues in addition totechnical issues. Intended for students with diverse technicalbackgrounds.Preference to Energy Studies minors.C. K. Colton, M. S. Strano, J. F. Hamel, W. A. Tisdale, G.Stephanopoulos

10.28 Chemical-Biological Engineering LaboratoryPrereq: 5.310 or 10.702[J]; 7.05 or 5.07[J]; or permission of instructorU (Fall)2-8-5 unitsCredit cannot also be received for 10.28L

Introduces the complete design of the bioprocess: from vectorselection to production, separation, and characterization ofrecombinant products. Utilize concepts from many fields, such as,chemical and electrical engineering, and biology. Student teamswork through parallel modules spanning microbial fermentationand animal cell culture. With the bioreactor at the core of theexperiments, students study cell metabolism and biologicalpathways, kinetics of cell growth and product formation, oxygenmass transport, scale-up and techniques for the design of processcontrol loops. Introduces novel bioreactors and powerful analyticalinstrumentation. Downstream processing and recombinant productpurification also included.Enrollment limited.J.-F. Hamel

10.28L Chemical-Biological Engineering LaboratoryPrereq: 5.310, 7.02[J], or 10.702[J]; 7.05 or 5.07[J]; or permission ofinstructorU (IAP, Spring)2-8-5 unitsCredit cannot also be received for 10.28

Spans IAP and spring term. Same as 10.28, but with the labportion of the class held during IAP rather than during the regularterm. Content, depth, and difficulty are otherwise identical tothat of 10.28. The class is designated as 10.28 on students'transcripts.Enrollment limited.J.-F. Hamel

10.29 Biological Engineering Projects LaboratorySubject meets with 10.26, 10.27Prereq: 2.671, 3.014, 5.310, 7.02[J], 12.335, or 1.106 and 1.107;10.302; or permission of instructorU (Spring)3-8-4 units

Projects in applied biological engineering research. Students workin teams on one project for the term. Projects often suggested bylocal industry. Includes training in research planning and projectmanagement, execution of experimental work, data analysis, oralpresentation skills and report writing, and team-building.C. K. Colton, J. F. Hamel, D. G. Anderson

10.291[J] Introduction to Sustainable EnergySame subject as 2.650[J], 22.081[J]Subject meets with 1.818[J], 2.65[J], 10.391[J], 11.371[J], 22.811[J]Prereq: Permission of instructorU (Fall)3-1-8 units

See description under subject 22.081[J].Limited to juniors andseniors.M. W. Golay

10.301 Fluid MechanicsPrereq: 18.03, 10.10U (Spring)4-0-8 units. REST

Introduces the mechanical principles governing fluid flow. Stressin a fluid. Conservation of mass and momentum, using differentialand integral balances. Elementary constitutive equations.Hydrostatics. Exact solutions of the Navier-Stokes equations.Approximate solutions using control volume analysis. Mechanicalenergy balances and Bernoulli's equation. Dimensional analysisand dynamic similarity. Introduces boundary-layer theory andturbulence.P. S. Doyle, F. R. Brushett

10.302 Transport ProcessesPrereq: 5.60, 10.301, 10.213; or permission of instructorU (Fall)4-0-8 units

Principles of heat and mass transfer. Steady and transientconduction and diffusion. Radiative heat transfer. Convectivetransport of heat and mass in both laminar and turbulent flows.Emphasis on the development of a physical understanding of theunderlying phenomena and upon the ability to solve real heat andmass transfer problems of engineering significance.W. A. Tisdale, K. Manthiram



10.31 Nanoscale Energy Transport ProcessesSubject meets with 10.51Prereq: 10.302 or 2.51; 3.024, 5.61, or 6.007; or permission ofinstructorU (Fall)Not offered regularly; consult department3-0-9 units

Explores the impact of nanoscale phenomena on macroscaletransport of energy-carrying molecules, phonons, electrons, andexcitons. Studies the effect of structural and energetic disorder,wave-like vs. particle-like transport, quantum and classical sizeeffects, and quantum coherence. Emphasizes quantitative analysis,including the Boltzmann transport equation, Einstein relation,Wiedemann-Franz law, and Marcus electron transfer theory.Also addresses percolation theory and the connection to energyconversion technologies, such as solar cells, thermoelectrics,and LEDs. Students taking graduate version complete additionalassignments.W. A. Tisdale

10.32 Separation ProcessesPrereq: 10.213, 10.302U (Spring)2-0-4 units

General principles of separation by equilibrium and rate processes.Staged cascades. Applications to distillation, absorption,adsorption, and membrane processes. Use of material balances,phase equilibria, and diffusion to understand and design separationprocesses.T. A. Hatton

10.333 Introduction to Modeling and SimulationEngineering School-Wide Elective Subject.Offered under: 1.021, 3.021, 10.333, 22.00Prereq: 18.03, 3.016, or permission of instructorU (Spring)4-0-8 units. REST

See description under subject 3.021.M. Buehler, R. Gomez-Bombarelli

10.34 Numerical Methods Applied to Chemical EngineeringPrereq: Permission of instructorG (Fall)3-0-6 units

Numerical methods for solving problems arising in heat and masstransfer, fluid mechanics, chemical reaction engineering, andmolecular simulation. Topics: numerical linear algebra, solution ofnonlinear algebraic equations and ordinary differential equations,solution of partial differential equations (e.g., Navier-Stokes),numerical methods in molecular simulation (dynamics, geometryoptimization). All methods are presented within the contextof chemical engineering problems. Familiarity with structuredprogramming is assumed.W. H. Green, J. W. Swan

10.345 Fundamentals of Metabolic and BiochemicalEngineering: Applications to BiomanufacturingSubject meets with 10.545Prereq: 5.07[J], 7.05, or permission of instructorU (Spring)3-0-9 units

Examines the fundamentals of cell and metabolic engineeringfor biocatalyst design and optimization, as well as biochemicalengineering principles for bioreactor design and operation, anddownstream processing. Presents applications of microbialprocesses for production of commodity and specialty chemicals andbiofuels in addition to mammalian cell cultures for production ofbiopharmaceuticals. Students taking graduate version completeadditional assignments.Gr. Stephanopoulos

10.37 Chemical Kinetics and Reactor DesignPrereq: 5.60, 10.301U (Spring)3-0-6 units

Applies the concepts of reaction rate, stoichiometry and equilibriumto the analysis of chemical and biological reacting systems.Derivation of rate expressions from reaction mechanisms andequilibrium or steady state assumptions. Design of chemical andbiochemical reactors via synthesis of chemical kinetics, transportphenomena, and mass and energy balances. Topics: chemical/biochemical pathways; enzymatic, pathway and cell growthkinetics; batch, plug flow and well-stirred reactors for chemicalreactions and cultivations of microorganisms and mammalian cells;heterogeneous and enzymatic catalysis; heat and mass transportin reactors, including diffusion to and within catalyst particles andcells or immoblized enzymes.Gr. Stephanopoulos, Y. Roman



10.390[J] Fundamentals of Advanced Energy ConversionSame subject as 2.60[J]Subject meets with 2.62[J], 10.392[J], 22.40[J]Prereq: 2.006, or 2.051 and 2.06, or permission of instructorAcad Year 2017-2018: Not offeredAcad Year 2018-2019: U (Spring)4-0-8 units

See description under subject 2.60[J].A. F. Ghoniem, W. Green

10.391[J] Sustainable EnergySame subject as 1.818[J], 2.65[J], 11.371[J], 22.811[J]Subject meets with 2.650[J], 10.291[J], 22.081[J]Prereq: Permission of instructorG (Fall)3-1-8 units

See description under subject 22.811[J].M. W. Golay

10.392[J] Fundamentals of Advanced Energy ConversionSame subject as 2.62[J], 22.40[J]Subject meets with 2.60[J], 10.390[J]Prereq: 2.006, or 2.051 and 2.06, or permission of instructorAcad Year 2017-2018: Not offeredAcad Year 2018-2019: G (Spring)4-0-8 units

See description under subject 2.62[J].A. F. Ghoniem, W. Green

10.40 Chemical Engineering ThermodynamicsPrereq: 10.213G (Fall)4-0-8 units

Basic postulates of classical thermodynamics. Application totransient open and closed systems. Criteria of stability andequilibria. Constitutive property models of pure materials andmixtures emphasizing molecular-level effects using the formalismof statistical mechanics. Phase and chemical equilibria ofmulticomponent systems. Applications emphasized throughextensive problem work relating to practical cases.D. Blankschtein

10.407[J] Funding Strategies for StartupsSame subject as 2.916[J]Prereq: NoneG (Spring; second half of term)2-0-4 units

Introduction to the substance and process of funding technologystartups. Topics include a comparative analysis of various sources ofcapital; templates to identify the optimal investor; legal frameworks,US and offshore, of the investment process and its related jargon;an introduction to understanding venture capital as a business;and market practice and standards for term sheet negotiation.Emphasizes strategy as well as tactics necessary to negotiate andbuild effective, long-term relationships with investors, particularlyventure capital firms (VCs).S. Loessberg, D. P. Hart

10.424 Pharmaceutical EngineeringSubject meets with 10.524Prereq: 10.213Acad Year 2017-2018: U (Fall)Acad Year 2018-2019: Not offered3-0-6 units

Presents engineering principles and unit operations involved in themanufacture of small molecules pharmaceuticals, from the isolationof purified active pharmaceutical ingredients (API) to the finalproduction of drug product. Regulatory issues include quality bydesign and process analytical technologies of unit operations, suchas crystallization, filtration, drying, milling, blending, granulation,tableting and coating. Also covers principles of formulation forsolid dosage forms and parenteral drugs. Students taking graduateversion complete additional assignments.Limited to 50.A. S. Myerson

10.426 Electrochemical Energy SystemsSubject meets with 10.626Prereq: 10.302 or permission of instructorU (Spring)3-0-9 units

Introduces electrochemical energy systems from the perspectiveof thermodynamics, kinetics, and transport. Surveys analysis anddesign of electrochemical reactions and processes by integratingchemical engineering fundamentals with knowledge from diversefields, including chemistry, electrical engineering, and materialsscience. Includes applications to fuel cells, electrolyzers, andbatteries. Students taking graduate version complete additionalassignments.K. Manthiram



10.43 Introduction to Interfacial PhenomenaPrereq: 10.213 or introductory subject in thermodynamics or physicalchemistryAcad Year 2017-2018: Not offeredAcad Year 2018-2019: G (Spring)3-0-6 units

Introduces fundamental and applied aspects of interfacial systems.Theory of capillarity. Experimental determination of surface andinterfacial tensions. Thermodynamics of interfaces. The Gibbsadsorption equation. Charged interfaces. Surfactant adsorptionat interfaces. Insoluble monolayers. Curvature effects on theequilibrium state of fluids. Nucleation and growth. Fundamentalsof wetting and contact angle. Adhesion, cohesion, and spreading.Wetting of textured surfaces. Super-hydrophilic and super-hydrophobic surfaces. Self-cleaning surfaces.D. Blankschtein

10.437[J] Computational ChemistrySame subject as 5.697[J]Subject meets with 5.698[J], 10.637[J]Prereq: NoneU (Fall)3-0-9 units

Addresses both the theory and application of first-principlescomputer simulations methods (i.e., quantum, chemical, orelectronic structure), including Hartree-Fock theory, densityfunctional theory, and correlated wavefunction methods. Coversenhanced sampling, ab initio molecular dynamics, and transition-path-finding approaches as well as errors and accuracy in totaland free energies. Discusses applications such as the studyand prediction of properties of chemical systems, includingheterogeneous, molecular, and biological catalysts (enzymes), andphysical properties of materials. Students taking graduate versioncomplete additional assignments.H. J. Kulik

10.441[J] Molecular and Engineering Aspects of BiotechnologySame subject as 7.37[J], 20.361[J]Prereq: 2.005, 3.012, 5.60, or 20.110[J]; 7.06; or permission ofinstructorU (Spring)Not offered regularly; consult department4-0-8 unitsCredit cannot also be received for 7.371

See description under subject 7.37[J].H. Lodish, L. Griffith

10.443 Future Medicine: Drug Delivery, Therapeutics, andDiagnosticsSubject meets with 10.643[J], HST.526[J]Prereq: 5.12 or permission of instructorAcad Year 2017-2018: Not offeredAcad Year 2018-2019: U (Spring)3-0-6 units

Aims to describe the direction and future of medical technology.Introduces pharmaceutics, pharmacology, and conventional medicaldevices, then transitions to drug delivery systems, mechanical/electric-based and biological/cell-based therapies, and sensors.Covers nano- and micro drug delivery systems, including polymer-drug conjugates, protein therapeutics, liposomes and polymernanoparticles, viral and non-viral genetic therapy, and tissueengineering. Previous coursework in cell biology and organicchemistry recommended. Students taking graduate versioncomplete additional assignments.Limited to 40.D. G. Anderson

10.450 Process Dynamics, Operations, and ControlPrereq: 10.302, 18.03U (Spring)3-0-6 units

Introduction to dynamic processes and the engineering tasks ofprocess operations and control. Subject covers modeling the staticand dynamic behavior of processes; control strategies; design offeedback, feedforward, and other control structures; model-basedcontrol; applications to process equipment.B. S. Johnston

10.466 Structure of Soft MatterSubject meets with 10.566Prereq: 5.60Acad Year 2017-2018: Not offeredAcad Year 2018-2019: U (Fall)3-0-6 units

Provides an introduction to the basic thermodynamic language usedfor describing the structure of materials, followed by a survey of thescattering, microscopy and spectroscopic techniques for structureand morphology characterization. Applies these concepts to a seriesof case studies illustrating the diverse structures formed in softmaterials and the common length, time and energy scales that unifythis field. For students interested in studying polymer science,colloid science, nanotechnology, biomaterials, and liquid crystals.Students taking graduate version complete additional assignments.B. D. Olsen



10.467 Polymer Science LaboratoryPrereq: 5.12, 5.310U (Fall)2-7-6 units

Experiments broadly aimed at acquainting students with the rangeof properties of polymers, methods of synthesis, and physicalchemistry. Examples: solution polymerization of acrylamide, beadpolymerization of divinylbenzene, interfacial polymerization of nylon6,10. Evaluation of networks by tensile and swelling experiments.Rheology of polymer solutions and suspensions. Physical propertiesof natural and silicone rubber.Preference to Course 10 seniors andjuniors.J. C. Love, D. G. Anderson

10.489 Concepts in Modern Heterogeneous CatalysisSubject meets with 10.689Prereq: 10.37, 10.302U (Spring)Not offered regularly; consult department3-0-6 units

Explores topics in the design and implementation of heterogeneouscatalysts for chemical transformations. Emphasizes use ofcatalysis for environmentally benign and sustainable chemicalprocesses. Lectures address concepts in catalyst preparation,catalyst characterization, quantum chemical calculations,and microkinetic analysis of catalytic processes. Shows howexperimental and theoretical approaches can illustrate importantreactive intermediates and transition states involved in chemicalreaction pathways, and uses that information to help identifypossible new catalysts that may facilitate reactions of interest.Draws examples from current relevant topics in catalysis. Includesa group project in which students investigate a specific topic ingreater depth. Students taking graduate version complete additionalassignments.Y. Roman

10.490 Integrated Chemical Engineering IPrereq: 10.37U (Fall; first half of term)3-0-5 units

Presents and solves chemical engineering problems in an industrialcontext, with applications varying by semester. Emphasis on theintegration of fundamental concepts with approaches of processdesign. Emphasis on problems that demand synthesis, economicanalysis, and process design.B. S. Johnston, Y. Roman

10.491 Integrated Chemical Engineering IIPrereq: 10.490U (Spring; first half of term)3-0-5 units

Presents and solves chemical engineering problems in an industrialcontext, with applications varying by term. Emphasis on theintegration of fundamental concepts with approaches of processdesign. Emphasis on problems that demand synthesis, economicanalysis, and process design.P. I. Barton, B. S. Johnston

10.492 Integrated Chemical Engineering Topics IPrereq: 10.301 and permission of instructorU (Fall; second half of term)2-0-2 units

Chemical engineering problems presented and analyzed in anindustrial context. Emphasizes the integration of fundamentals withmaterial property estimation, process control, product development,and computer simulation. Integration of societal issues, such asengineering ethics, environmental and safety considerations, andimpact of technology on society are addressed in the context of casestudies. 10.37 and 10.302 required for certain topic modules. Seedepartmental website for individual ICE-T module descriptions.K. F. Jensen, Geo. Stephanopoulos

10.493 Integrated Chemical Engineering Topics IIPrereq: 10.301 and permission of instructorU (IAP)2-0-2 units

Chemical engineering problems presented and analyzed in anindustrial context. Emphasizes the integration of fundamentals withmaterial property estimation, process control, product development,and computer simulation. Integration of societal issues, such asengineering ethics, environmental and safety considerations, andimpact of technology on society are addressed in the context of casestudies. 10.37 and 10.302 required for certain topic modules. Seedepartmental website for individual ICE-T module descriptions.R. E. Cohen, B. S. Johnston, J. Drake



10.494 Integrated Chemical Engineering Topics IIIPrereq: 10.301 and permission of instructorU (Spring)2-0-2 units

Chemical engineering problems presented and analyzed in anindustrial context. Emphasizes the integration of fundamentals withmaterial property estimation, process control, product development,and computer simulation. Integration of societal issues, such asengineering ethics, environmental and safety considerations, andimpact of technology on society are addressed in the context of casestudies. 10.37 and 10.302 required for certain topic modules. Seedepartmental website for individual ICE-T module descriptions.K. F. Jensen, R. C. Armstrong

10.495 Molecular Design and Bioprocess Development ofImmunotherapiesSubject meets with 10.595Prereq: 7.06 or permission of instructorU (Spring)Not offered regularly; consult department3-0-6 units

Examines challenges and opportunities for applying chemicalengineering principles to address the growing global burden ofinfectious disease, including drug-resistant strains and neglectedpathogens. Topics include a historical overview of vaccines andimmunotherapies, the molecular design considerations for newimmunotherapies and adjuvants, the economic challenges forprocess development and manufacturing of immunotherapies,and new technologies for designing and assessing therapies.Case studies to cover topics for specific diseases. Students takinggraduate version complete additional assignments.J. C. Love

10.50 Analysis of Transport PhenomenaPrereq: 10.301, 10.302G (Fall)4-0-8 units

Unified treatment of heat transfer, mass transfer, and fluidmechanics, emphasizing scaling concepts in formulating modelsand analytical methods for obtaining solutions. Topics includeconduction and diffusion, laminar flow regimes, convective heatand mass transfer, and simultaneous heat and mass transfer withchemical reaction or phase change.W. M. Deen, M. Z. Bazant

10.51 Nanoscale Energy Transport ProcessesSubject meets with 10.31Prereq: 10.302 or 2.51; 3.024, 5.61, or 6.007; or permission ofinstructorG (Fall)Not offered regularly; consult department3-0-9 units

Explores the impact of nanoscale phenomena on macroscaletransport of energy-carrying molecules, phonons, electrons, andexcitons. Studies the effect of structural and energetic disorder,wave-like vs. particle-like transport, quantum and classical sizeeffects, and quantum coherence. Emphasizes quantitative analysis,including the Boltzmann transport equation, Einstein relation,Wiedemann-Franz law, and Marcus electron transfer theory.Also addresses percolation theory and the connection to energyconversion technologies, such as solar cells, thermoelectrics,and LEDs. Students taking graduate version complete additionalassignments.W. A. Tisdale

10.52 Mechanics of FluidsPrereq: 10.50G (Fall)Not offered regularly; consult department3-0-6 units

Advanced subject in fluid and continuum mechanics. Contentincludes kinematics, macroscopic balances for linear and angularmomentum, the stress tensor, creeping flows and the lubricationapproximation, the boundary layer approximation, linear stabilitytheory, and some simple turbulent flows.Staff

10.524 Pharmaceutical EngineeringSubject meets with 10.424Prereq: NoneAcad Year 2017-2018: G (Fall)Acad Year 2018-2019: Not offered3-0-6 units

Presents engineering principles and unit operations involved in themanufacture of small molecules pharmaceuticals, from the isolationof purified active pharmaceutical ingredients (API) to the finalproduction of drug product. Regulatory issues include quality bydesign and process analytical technologies of unit operations, suchas crystallization, filtration, drying, milling, blending, granulation,tableting and coating. Also covers principles of formulation forsolid dosage forms and parenteral drugs. Students taking graduateversion complete additional assignments.Limited to 50.A. S. Myerson



10.53[J] Advances in BiomanufacturingSame subject as 7.548[J]Subject meets with 7.458[J], 10.03[J]Prereq: NoneG (Spring; second half of term)1-0-2 units

Seminar examines how biopharmaceuticals, an increasinglyimportant class of pharmaceuticals, are manufactured. Topicsrange from fundamental bioprocesses to new technologies tothe economics of biomanufacturing. Also covers the impact ofglobalization on regulation and quality approaches as well assupply chain integrity. Students taking graduate version completeadditional assignments.J. C. Love, A. Sinskey, S. Springs

10.531[J] Macromolecular HydrodynamicsSame subject as 2.341[J]Prereq: 2.25, 10.301, or permission of instructorAcad Year 2017-2018: G (Spring)Acad Year 2018-2019: Not offered3-0-6 units

See description under subject 2.341[J].R. C. Armstrong, G. H. McKinley

10.536[J] Thermal Hydraulics in Power TechnologySame subject as 2.59[J], 22.313[J]Prereq: 2.006, 10.302, 22.312, or permission of instructorAcad Year 2017-2018: G (Fall)Acad Year 2018-2019: Not offered3-2-7 units

See description under subject 22.313[J].E. Baglietto, M. Bucci

10.537[J] Molecular, Cellular, and Tissue BiomechanicsSame subject as 2.798[J], 3.971[J], 6.524[J], 20.410[J]Prereq: Biology (GIR); 2.002, 2.006, 6.013, 10.301, or 10.302Acad Year 2017-2018: Not offeredAcad Year 2018-2019: G (Fall)3-0-9 units

See description under subject 20.410[J].R. D. Kamm, K. J. Van Vliet

10.538[J] Principles of Molecular BioengineeringSame subject as 20.420[J]Prereq: 7.06, 18.03G (Fall)3-0-9 units

See description under subject 20.420[J].A. Jasanoff, E. Fraenkel

10.539[J] Fields, Forces, and Flows in Biological SystemsSame subject as 2.795[J], 6.561[J], 20.430[J]Prereq: Permission of instructorG (Fall)3-0-9 units

See description under subject 20.430[J].M. Bathe, A. J. Grodzinsky

10.540 Intracellular DynamicsPrereq: 18.03, 7.06, 10.302, or permission of instructorAcad Year 2017-2018: Not offeredAcad Year 2018-2019: G (Spring)3-0-9 units

Covers current models and descriptions of the internal cell dynamicsof macromolecules due to reaction and transport. Two major areaswill be explored: the process of gene expression, including protein-DNA interactions, chromatin dynamics, and the stochastic natureof gene expression; and cell signaling systems, especially thosethat lead to or rely on intracellular protein gradients. This classis intended for graduate students or advanced undergraduateswith some background in cell biology, transport, and kinetics. Anintroductory class in probability is recommended.N. Maheshri

10.542 Biochemical EngineeringPrereq: Permission of instructorAcad Year 2017-2018: Not offeredAcad Year 2018-2019: G (Spring)3-0-6 units

Interaction of chemical engineering, biochemistry, andmicrobiology. Mathematical representations of microbialsystems. Kinetics of growth, death, and metabolism. Continuousfermentation, agitation, mass transfer, and scale-up in fermentationsystems, enzyme technology.K. J. Prather



10.544 Metabolic and Cell EngineeringPrereq: 7.05, 10.302, 18.03G (Fall, Spring)Not offered regularly; consult department3-0-9 units

Presentation of a framework for quantitative understanding of cellfunctions as integrated molecular systems. Analysis of cell-levelprocesses in terms of underlying molecular mechanisms based onthermodynamics, kinetics, mechanics, and transport principles,emphasizing an engineering, problem-oriented perspective.Objective is to rationalize target selection for genetic engineeringand evaluate the physiology of recombinant cells. Topics includecell metabolism and energy production, transport across cellcompartment barriers, protein synthesis and secretion, regulationof gene expression, transduction of signals from extracellularenvironment, cell proliferation, cell adhesion and migration.Gr. Stephanopoulos

10.545 Fundamentals of Metabolic and Biochemical Engineering:Applications to BiomanufacturingSubject meets with 10.345Prereq: 5.07[J], 7.05, or permission of instructorG (Spring)3-0-9 units

Examines the fundamentals of cell and metabolic engineeringfor biocatalyst design and optimization, as well as biochemicalengineering principles for bioreactor design and operation, anddownstream processing. Presents applications of microbialprocesses for production of commodity and specialty chemicals andbiofuels in addition to mammalian cell cultures for production ofbiopharmaceuticals. Students taking graduate version completeadditional assignments.Gr. Stephanopoulos

10.546[J] Statistical ThermodynamicsSame subject as 5.70[J]Prereq: 5.60 or permission of instructorG (Fall)3-0-9 units

See description under subject 5.70[J].B. Zhang

10.547[J] Principles and Practice of Drug DevelopmentSame subject as 7.547[J], 15.136[J], HST.920[J], IDS.620[J]Prereq: Permission of instructorG (Fall)3-0-6 units

See description under subject 15.136[J].T. J. Allen, C. L. Cooney, S. N. Finkelstein, A. J. Sinskey, G. K. Raju

10.548[J] Tumor Microenvironment and Transport Phenomena: ASystems Biology ApproachSame subject as HST.525[J]Prereq: 18.03; 10.301Acad Year 2017-2018: G (Fall)Acad Year 2018-2019: Not offered2-0-4 units

See description under subject HST.525[J].R. K. Jain

10.55 Colloid and Surfactant SciencePrereq: Permission of instructorG (Fall)Not offered regularly; consult department3-0-6 units

Introduces fundamental and applied aspects of colloidaldispersions, where the typical particle size is less than amicrometer. Discusses the characterization and unique behaviorof colloidal dispersions, including their large surface-to-volumeratio, tendency to sediment in gravitational and centrifugal fields,diffusion characteristics, and ability to generate osmotic pressureand establish Donnan equilibrium. Covers the fundamentals ofattractive van der Waals forces and repulsive electrostatic forces.Presents an in-depth discussion of electrostatic and polymer-induced colloid stabilization, including the DLVO theory of colloidstability. Presents an introductory discussion of surfactant physicalchemistry.D. Blankschtein

10.551 Systems EngineeringPrereq: 10.213, 10.302, 10.37G (Spring)3-0-6 units

Introduction to the elements of systems engineering. Specialattention devoted to those tools that help students structureand solve complex problems. Illustrative examples drawn from abroad variety of chemical engineering topics, including productdevelopment and design, process development and design,experimental and theoretical analysis of physico-chemical process,analysis of process operations.Geo. Stephanopoulos, R. D. Braatz



10.552 Advanced Systems EngineeringPrereq: NoneG (Fall)3-0-6 units

Covers modern methods for dynamical systems analysis, stateestimation, controller design, and related topics. Uses exampleapplications to demonstrate Lyapunov and linear matrix inequality-based methods that explicitly address actuator constraints,nonlinearities, and model uncertainties.Limited to 30.R. D. Braatz

10.555[J] Bioinformatics: Principles, Methods and ApplicationsSame subject as HST.940[J]Prereq: Permission of instructorAcad Year 2017-2018: Not offeredAcad Year 2018-2019: G (Spring)3-0-9 units

Introduction to bioinformatics, the collection of principles andcomputational methods used to upgrade the information contentof biological data generated by genome sequencing, proteomics,and cell-wide physiological measurements of gene expression andmetabolic fluxes. Fundamentals from systems theory presented todefine modeling philosophies and simulation methodologies forthe integration of genomic and physiological data in the analysisof complex biological processes. Various computational methodsaddress a broad spectrum of problems in functional genomicsand cell physiology. Application of bioinformatics to metabolicengineering, drug design, and biotechnology also discussed.Gr. Stephanopoulos, I. Rigoutsos

10.557 Mixed-integer and Nonconvex OptimizationPrereq: 10.34 or 15.053G (Spring)Not offered regularly; consult department3-0-9 units

Presents the theory and practice of deterministic algorithms forlocating the global solution of NP-hard optimization problems.Recurring themes and methods are convex relaxations, branch-and-bound, cutting planes, outer approximation and primal-relaxeddual approaches. Emphasis is placed on the connections betweenmethods. These methods will be applied and illustrated in thedevelopment of algorithms for mixed-integer linear programs,mixed-integer convex programs, nonconvex programs, mixed-integer nonconvex programs, and programs with ordinarydifferential equations embedded. The broad range of engineeringapplications for these optimization formulations will also beemphasized. Students will be assessed on homework and a termproject for which examples from own research are encouraged.P. I. Barton

10.56 Advanced Topics in Surfactant SciencePrereq: Permission of instructorAcad Year 2017-2018: Not offeredAcad Year 2018-2019: G (Spring)3-0-6 units

Introduces fundamental advances and practical aspects ofsurfactant self-assembly in aqueous media. In-depth discussion ofsurfactant micellization, including statistical-thermodynamics ofmicellar solutions, models of micellar growth, molecular models forthe free energy of micellization, and geometric packing theories.Presents an introductory examination of mixed micelle and vesicleformation, polymer-surfactant complexation, biomolecule-surfactantinteractions, and micellar-assisted solubilization. Discussesmolecular dynamics simulations of self-assembling systems. Coversrecent advances in surfactant-induced dispersion and stabilizationof colloidal particles (e.g., carbon nanotubes and graphene) inaqueous media. Examines surfactant applications in consumerproducts, environmental and biological separations, enhancedoil recovery using surfactant flooding, mitigation of skin irritationinduced by surfactant-containing cosmetic products, and enhancedtransdermal drug delivery using ultrasound and surfactants.D. Blankschtein

10.560 Structure and Properties of PolymersPrereq: 10.213 or permission of instructorG (Spring)3-0-6 units

Review of polymer molecular structure and bulk morphology;survey of molecular and morphological influence on bulk physicalproperties including non-Newtonian flow, macromolecular diffusion,gas transport in polymers, electrical and optical properties, solid-state deformation, and toughness. Case studies for product design.R. E. Cohen

10.562[J] Pioneering Technologies for Interrogating ComplexBiological SystemsSame subject as HST.562[J]Prereq: NoneG (Spring)3-1-8 units

See description under subject HST.562[J].Limited to 15.K. Chung



10.566 Structure of Soft MatterSubject meets with 10.466Prereq: 5.60Acad Year 2017-2018: Not offeredAcad Year 2018-2019: G (Fall)3-0-6 units

Provides an introduction to the basic thermodynamic language usedfor describing the structure of materials, followed by a survey of thescattering, microscopy and spectroscopic techniques for structureand morphology characterization. Applies these concepts to a seriesof case studies illustrating the diverse structures formed in softmaterials and the common length, time and energy scales that unifythis field. For students interested in studying polymer science,colloid science, nanotechnology, biomaterials, and liquid crystals.Students taking graduate version complete additional assignments.B. D. Olsen

10.568 Physical Chemistry of PolymersPrereq: 5.60, 10.213, or 10.40G (Fall, Spring)3-0-6 units

Chain macromolecules as random coils (unperturbed, expanded)and as other shapes. Statistical thermodynamics of interpenetratingrandom coiling polymers in solution with application to phaseseparations, swelling of networks, depression of melting point.The isolated chain molecule in dilute solutions analyzed for massor size by static methods (osmometry, light scattering, neutronscattering) and by dynamic methods (intrinsic viscosity, sizeexclusion chromatography, sedimentation). Introduction to chaindynamics and to rubber elasticity.G. C. Rutledge, A. Alexander-Katz

10.569 Synthesis of PolymersPrereq: 5.12G (Spring)3-0-6 units

Studies synthesis of polymeric materials, emphasizinginterrelationships of chemical pathways, process conditions,and microarchitecture of molecules produced. Chemicalpathways include traditional approaches such as anionic, radicalcondensation, and ring-opening polymerizations. New techniques,including stable free radicals and atom transfer free radicals, newcatalytic approaches to well-defined architectures, and polymerfunctionalization in bulk and at surfaces. Process conditionsinclude bulk, solution, emulsion, suspension, gas phase, andbatch vs continuous fluidized bed. Microarchitecture includestacticity, molecular-weight distribution, sequence distributionsin copolymers, errors in chains such as branches, head-to-headaddition, and peroxide incorporation.P. T. Hammond, B. D. Olsen

10.571[J] Atmospheric Physics and ChemistrySame subject as 12.806[J]Subject meets with 12.306Prereq: 5.60 or 5.61; 18.075; or permission of instructorG (Spring)3-0-9 units

See description under subject 12.806[J].R. G. Prinn

10.579[J] Energy Technology and Policy: From Principles toPracticeSame subject as 5.00[J], 6.929[J], 22.813[J]Prereq: NoneG (Spring)Not offered regularly; consult department3-0-6 units

Develops analytical skills to lead a successful technologyimplementation with an integrated approach that combinestechnical, economical and social perspectives. Considers corporateand government viewpoints as well as international aspects,such as nuclear weapons proliferation and global climate issues.Discusses technologies such as oil and gas, nuclear, solar, andenergy efficiency.Limited to 100.J. Deutch

10.580 Solid-State Surface SciencePrereq: 10.213G (Fall)Not offered regularly; consult department3-0-6 units

Structural, chemical, and electronic properties of solids and solidsurfaces. Analytical tools used to characterize surfaces includingAuger and photoelectron spectroscopies and electron diffractiontechniques. Surface thermodynamics and kinetics includingadsorption-desorption, catalytic properties, and sputteringprocesses. Applications to microelectronics, optical materials, andcatalysis.K. K. Gleason



10.585 Engineering NanotechnologyPrereq: 10.302, 10.213, or permission of instructorG (Fall)3-0-9 units

Review of fundamental concepts of energy, mass and electrontransport in materials confined or geometrically patterned at thenanoscale, where departures from classical laws are dominant.Specific applications to contemporary engineering challengesare discussed including problems in energy, biology, medicine,electronics, and material design.M. Strano

10.586 Crystallization Science and TechnologyPrereq: 10.213Acad Year 2017-2018: Not offeredAcad Year 2018-2019: G (Fall)3-0-6 units

Studies the nucleation and growth of crystals from a melt or a liquidsolution and their important role in a wide range of applications,including pharmaeuticals, proteins, and semiconductor materials.Provides background information and covers topics neededto understand, perform experiments, construct and simulatemechanistic models, and design, monitor, and control crystallizationprocesses.Limited to 30.A. S. Myerson

10.591 Case Studies in BioengineeringPrereq: Biology (GIR) or permission of instructorG (Fall)3-0-6 units

Analysis and discussion of recent research in areas ofbioengineering, including drug delivery, protein and tissueengineering, physiological transport, stem cell technology, andquantitative immunology by senior investigators in the Boston area.Students will read and critique papers, then have discussions withauthors about their work.C. K. Colton

10.595 Molecular Design and Bioprocess Development ofImmunotherapiesSubject meets with 10.495Prereq: Permission of instructorG (Spring)Not offered regularly; consult department3-0-6 units

Examines challenges and opportunities for applying chemicalengineering principles to address the growing global burden ofinfectious disease, including drug-resistant strains and neglectedpathogens. Topics include a historical overview of vaccines andimmunotherapies, the molecular design considerations for newimmunotherapies and adjuvants, the economic challenges forprocess development and manufacturing of immunotherapies,and new technologies for designing and assessing therapies.Case studies to cover topics for specific diseases. Students takinggraduate version complete additional assignments.J. C. Love

10.606 Visual Strategies for Scientists and EngineersPrereq: NoneG (Spring; first half of term)1-2-2 units

Provides instruction in best practices for creating more effectivegraphics and photographs to support and communicate research inscience and engineering. Discusses in depth specific examples froma range of scientific contexts, such as journal articles, presentations,grant submissions, and cover art. Topics include graphics forfigures depicting form and structure, process, and change overtime. Prepares students to create effective graphics for submissionsto existing journals and calls attention to the future of publishedgraphics with the advent of interactivity.Limited to 10.F. Frankel

10.625[J] Electrochemical Energy Conversion and Storage:Fundamentals, Materials and ApplicationsSame subject as 2.625[J]Prereq: 2.005, 3.046, 3.53, 10.40, or 2.051 and 2.06, or permissionof instructorAcad Year 2017-2018: Not offeredAcad Year 2018-2019: G (Fall)4-0-8 units

See description under subject 2.625[J].Y. Shao-Horn



10.626 Electrochemical Energy SystemsSubject meets with 10.426Prereq: 10.50 or permission of instructorG (Spring)3-0-9 units

Introduces electrochemical energy systems from the perspectiveof thermodynamics, kinetics, and transport. Surveys analysis anddesign of electrochemical reactions and processes by integratingchemical engineering fundamentals with knowledge from diversefields, including chemistry, electrical engineering, and materialsscience. Includes applications to fuel cells, electrolyzers, andbatteries. Students taking graduate version complete additionalassignments.K. Manthiram

10.631 Structural Theories of Polymer Fluid MechanicsPrereq: 10.301G (Spring)3-0-6 units

Structural and molecular models for polymeric liquids.Nonequilibrium properties are emphasized. Elementary kinetictheory of polymer solutions. General phase space kinetic for polymermelts and solutions. Network theories. Interrelations betweenstructure and rheological properties.R. C. Armstrong

10.637[J] Quantum Chemical SimulationSame subject as 5.698[J]Subject meets with 5.697[J], 10.437[J]Prereq: NoneG (Fall)3-0-9 units

Addresses both the theory and application of first-principlescomputer simulations methods (i.e., quantum, chemical, orelectronic structure), including Hartree-Fock theory, densityfunctional theory, and correlated wavefunction methods. Coversenhanced sampling, ab initio molecular dynamics, and transition-path-finding approaches as well as errors and accuracy in totaland free energies. Discusses applications such as the studyand prediction of properties of chemical systems, includingheterogeneous, molecular, and biological catalysts (enzymes), andphysical properties of materials. Students taking graduate versioncomplete additional assignments.H. J. Kulik

10.643[J] Future Medicine: Drug Delivery, Therapeutics, andDiagnosticsSame subject as HST.526[J]Subject meets with 10.443Prereq: 5.12 or permission of instructorAcad Year 2017-2018: Not offeredAcad Year 2018-2019: G (Spring)3-0-6 units

Aims to describe the direction and future of medical technology.Introduces pharmaceutics, pharmacology, and conventional medicaldevices, then transitions to drug delivery systems, mechanical/electric-based and biological/cell-based therapies, and sensors.Covers nano- and micro drug delivery systems, including polymer-drug conjugates, protein therapeutics, liposomes and polymernanoparticles, viral and non-viral genetic therapy, and tissueengineering. Previous coursework in cell biology and organicchemistry recommended. Students taking graduate versioncomplete additional assignments.Limited to 40.D. G. Anderson

10.644[J] Frontiers in Therapeutics and Drug DeliverySame subject as HST.914[J]Prereq: 7.05 or permission of instructorG (Fall)Not offered regularly; consult department3-0-6 units

Provides an introduction to pharmaceutics and conventional oral,injected, transdermal and inhaled drug delivery systems. Includesstudies of drug delivery devices and systems, e.g., stents, pumps,depo systems, responsive drug delivery systems, and biological/cell based therapies. Covers nano- and micro drug delivery systems,including polymer-drug conjugates, modified proteins, liposomesand polymer nanoparticles, viral and non-viral genetic therapy,and microencapsulated vaccines. Discusses reviews and currenttechnology. Students taking graduate version complete additionalassignments.Limited to 40.D. G. Anderson



10.65 Chemical Reactor EngineeringPrereq: 10.37 or permission of instructorG (Spring)4-0-8 units

Fundamentals of chemically reacting systems with emphasis onsynthesis of chemical kinetics and transport phenomena. Topicsinclude kinetics of gas, liquid, and surface reactions; quantumchemistry; transition state theory; surface adsorption, diffusion,and desorption processes; mechanism and kinetics of biologicalprocesses; mechanism formulation and sensitivity analysis. Reactortopics include nonideal flow reactors, residence time distributionand dispersion models; multiphase reaction systems; nonlinearreactor phenomena. Examples are drawn from different applications,including heterogeneous catalysis, polymerization, combustion,biochemical systems, and materials processing.M. Strano, G. Stephanopoulos

10.652[J] Kinetics of Chemical ReactionsSame subject as 5.68[J]Prereq: 5.62, 10.37, or 10.65Acad Year 2017-2018: Not offeredAcad Year 2018-2019: G (Fall)3-0-6 units

See description under subject 5.68[J].W. H. Green

10.668[J] Statistical Mechanics of PolymersSame subject as 3.941[J]Prereq: 10.568 or permission of instructorAcad Year 2017-2018: Not offeredAcad Year 2018-2019: G (Fall)3-0-9 units

Concepts of statistical mechanics and thermodynamics appliedto macromolecules: polymer conformations in melts, solutions,and gels; Rotational Isomeric State theory, Markov processes andmolecular simulation methods applied to polymers; incompatibilityand segregation in incompressible and compressible systems;molecular theory of viscoelasticity; relation to scattering andexperimental measurements.G. C. Rutledge, A. Alexander-Katz

10.677 Topics in Applied MicrofluidicsPrereq: 10.301 or permission of instructor.G (Fall)3-0-6 units

Provides an introduction to the field of microfluidics. Reviewsfundamental concepts in transport phenomena and dimensionalanalysis, focusing on new phenomena which arise at smallscales. Discusses current applications, with an emphasis on thecontributions engineers bring to the field. Local and visiting expertsin the field discuss their work.Limited to 30.P. Doyle

10.689 Concepts in Modern Heterogeneous CatalysisSubject meets with 10.489Prereq: 10.37, 10.302G (Spring)Not offered regularly; consult department3-0-6 units

Explores topics in the design and implementation of heterogeneouscatalysts for chemical transformations. Emphasizes use ofcatalysis for environmentally benign and sustainable chemicalprocesses. Lectures address concepts in catalyst preparation,catalyst characterization, quantum chemical calculations,and microkinetic analysis of catalytic processes. Shows howexperimental and theoretical approaches can illustrate importantreactive intermediates and transition states involved in chemicalreaction pathways, and uses that information to help identifypossible new catalysts that may facilitate reactions of interest.Draws examples from current relevant topics in catalysis. Includesa group project in which students investigate a specific topic ingreater depth. Students taking graduate version complete additionalassignments.Y. Roman

10.702[J] Introduction to Experimental Biology andCommunicationSame subject as 7.02[J]Prereq: Biology (GIR)U (Fall, Spring)4-8-6 units. Institute LAB

Introduction to the experimental concepts and methods ofmolecular biology, biochemistry, and genetic analysis. Emphasison experimental design, critical data analysis, and the developmentof written communications skills. 12 units may be applied to theGeneral Institute Laboratory Requirement.Enrollment limited.T. Baker, M. Gehring, K. D. Wittrup, O. Yilmaz, L. Boyer, K. D. Wittrup



10.792[J] Global Operations Leadership SeminarSame subject as 2.890[J], 15.792[J], 16.985[J]Prereq: NoneG (Fall, Spring)Units arranged [P/D/F]Can be repeated for credit.

See description under subject 15.792[J].Preference to LGO students.T. Roemer

10.805[J] Technology, Law, and the Working EnvironmentSame subject as IDS.436[J]Subject meets with 1.802[J], 1.812[J], 11.022[J], 11.631[J], IDS.061[J],IDS.541[J]Prereq: Permission of instructorG (Spring)Not offered regularly; consult department3-0-6 units

See description under subject IDS.436[J].N. A. Ashford, C. C. Caldart

10.806 Management in EngineeringEngineering School-Wide Elective Subject.Offered under: 2.96, 6.930, 10.806, 16.653Prereq: NoneU (Fall)3-1-8 units

See description under subject 2.96.Restricted to juniors and seniors.H. S. Marcus, J.-H. Chun

10.807[J] Innovation TeamsSame subject as 15.371[J]Prereq: 15.911 or permission of instructorG (Fall, Spring)4-4-4 units

Introduces skills and capabilities for systematic technicaland functional exploration, opportunity discovery, marketunderstanding, value economics, innovation scale-up, intellectualproperty, elements of technology commercialization at scale,and communicating/working for impact inside and outside homedisciplines. Students work in multidisciplinary teams formedaround MIT research breakthroughs, with extensive in-classcoaching from faculty and guidance from lab members and selectmentors. Demonstrates a structured approach to innovatingin which everything is a variable and the product, technology,and opportunities for new ventures can be seen as an act ofsynthesis. Teams gather evidence that permits a fact-based iterationacross multiple application domains, markets, functionalities,technologies, and products, leading to a recommendation thatmaps a space of opportunity and includes actionable next steps toevolve the market and technology.Applications, resumes, and a briefstatement of interest are required prior to registration.F. Murray, L. Perez-Breva

10.817[J] Atmospheric ChemistrySame subject as 1.84[J], 12.807[J]Prereq: 5.60G (Fall)3-0-9 units

See description under subject 1.84[J].J. H. Kroll

School of Chemical Engineering Practice

10.80 (10.82, 10.84, 10.86) School of Chemical EngineeringPractice -- Technical AccomplishmentPrereq: NoneG (Fall, Spring, Summer)0-6-0 units

Conducted at industrial field stations of the School of ChemicalEngineering Practice. Group problem assignments include processdevelopment design, simulation and control, technical service,and new-product development. Grading based on technicalaccomplishment. Credit granted in lieu of master's thesis. Seedepartmental descripton on School of Chemical Engineering Practicefor details.Enrollment limited and subject to plant availability.T. A. Hatton



10.81 (10.83, 10.85, 10.87) School of Chemical EngineeringPractice -- Communication Skills and Human RelationsPrereq: NoneG (Fall, Spring, Summer)0-6-0 units

Conducted at industrial field stations of the School of ChemicalEngineering Practice. Group problem assignments include processdevelopment, design, simulation and control, technical service, andnew-product development. Grading based on communication skillsand human relations in group assignments. Credit granted in lieu ofmaster's thesis; see departmental description on School of ChemicalEngineering Practice for details.Enrollment limited and subject toplant availability.T. A. Hatton

General

10.90 Independent Research ProblemPrereq: Permission of instructorG (Fall, Spring, Summer)Units arrangedCan be repeated for credit.

For special and graduate students who wish to carry out some minorinvestigation in a particular field. Subject and hours to fit individualrequirements.R. D. Braatz

10.910 Independent Research ProblemPrereq: NoneU (Fall, IAP, Spring, Summer)Units arrangedCan be repeated for credit.

For undergraduate students who wish to carry out a specialinvestigation in a particular field. Topic and hours arranged.B. S. Johnston

10.911 Independent Research ProblemPrereq: NoneU (Fall, IAP, Spring, Summer)Units arranged [P/D/F]Can be repeated for credit.

For undergraduate students who wish to carry out a specialinvestigation in a particular field. Topic and hours arranged.B. S. Johnston

10.953 Seminar in Heterogeneous CatalysisPrereq: NoneG (Fall, Spring)2-0-4 unitsCan be repeated for credit.

Students present their research to other students and staff.Research topics include heterogeneous catalysis, design of catalyticmaterials, biomass conversion, biofuels, and CO2 utilization.Y. Roman

10.954 Seminar in Applied Optical SpectroscopyPrereq: Permission of instructorG (Fall, Spring)2-0-4 unitsCan be repeated for credit.

Research seminars given by students, postdocs, and visitors.Topics covered include applied optical spectroscopy and imaging,with particular emphasis on nanomaterials and how they relate toalternative energy technologies.W. A. Tisdale

10.955 Seminar in Electrochemical EngineeringPrereq: Permission of instructorG (Fall, Spring)2-0-4 unitsCan be repeated for credit.

Designed to allow students to present and discuss their researchin the area of electrochemical engineering with a particularemphasis on energy storage and conversion (e.g., batteries, fuelcells, electroreactors). Specific topics include active materialsdesign, electroanalytical platform development, and integration ofelectrochemical and imaging techniques.F. R. Brushett

10.956 Seminar in Atomistic SimulationPrereq: Permission of instructorG (Fall, Spring)2-0-4 unitsCan be repeated for credit.

Seminar allows students to present their research to other studentsand staff. The research topics include electronic structure theory,computational chemistry techniques, and density functional theorywith a focus on applications to catalysis and materials science.H. J. Kulik



10.957 Seminar in Bioengineering TechnologyPrereq: Permission of instructorG (Fall, Spring)2-0-4 unitsCan be repeated for credit.

Research seminars presented by students and guest speakers onemerging biotechnologies.K. Chung

10.958 Seminar in the Fluid Mechanics and Self-assembly ofSoft MatterPrereq: Permission of instructorG (Fall, Spring)2-0-4 unitsCan be repeated for credit.

Covers topics related to low Reynolds number hydrodynamics andthe statistical physics of particulate media. Specifics include thekinetics of phase transitions in soft matter and the time-varyingdeformation of colloidal dispersions, glasses and gels.J. W. Swan

10.960[J] Seminar in Polymers and Soft MatterSame subject as 3.903[J]Prereq: NoneG (Fall, Spring)2-0-0 unitsCan be repeated for credit.

A series of seminars covering a broad spectrum of topics in polymerscience and engineering, featuring both on- and off-campusspeakers.A. Alexander-Katz, R. E. Cohen, D. Irvine

10.961 Seminar in Advanced Air Pollution ResearchPrereq: Permission of instructorG (Fall, Spring)Not offered regularly; consult department2-0-4 unitsCan be repeated for credit.

Research seminars, presented by students engaged in thesis workin the field of air pollution. Particular emphasis given to atmosphericchemistry, mathematical modeling, and policy analysis.G. J. McRae

10.962 Seminar in Molecular Cell EngineeringPrereq: Permission of instructorG (Fall, Spring)2-0-4 unitsCan be repeated for credit.

Weekly seminar with discussion of ongoing research and relevantliterature by graduate students, postdoctoral fellows, and visitingscientists on issues at the interface of chemical engineeringwith molecular cell biology. Emphasis is on quantitative aspectsof physicochemical mechanisms involved in receptor/ligandinteractions, receptor signal transduction processes, receptor-mediated cell behavioral responses, and applications of these inbiotechnology and medicine.D. A. Lauffenburger

10.964 Seminar on Transport TheoryPrereq: Permission of instructorG (Fall, Spring)2-0-4 unitsCan be repeated for credit.

Research seminars presented by students and guest speakerson mathematical modeling of transport phenomena, focusing onelectrochemical systems, electrokinetics, and microfluidics.M. Z. Bazant

10.965 Seminar in Biosystems EngineeringPrereq: Permission of instructorG (Fall, Spring)2-0-4 unitsCan be repeated for credit.

Advanced topics on the state-of-the-art in design andimplementation of analytical processes for biological systems,including single-cell analysis, micro/nanotechnologies, systemsbiology, biomanufacturing, and process engineering. Seminarsand discussions guided by the research interests of participatinggraduate students, postdoctoral associates, faculty, and visitinglecturers.J. C. Love



10.966 Seminar in Drug Delivery, Biomaterials, and TissueEngineeringPrereq: Permission of instructorG (Fall, Spring)2-0-4 unitsCan be repeated for credit.

Focuses on presentations by students and staff on current researchin the area of drug delivery, biomaterials, and tissue engineering.Includes topics such as nanotherapeutics, intracellular delivery, andtherapies for diabetes.D. G. Anderson

10.967 Seminar in Protein-Polymer Materials EngineeringPrereq: Permission of instructorG (Fall, Spring)2-0-4 unitsCan be repeated for credit.

Research seminar covers topics on protein-based polymericmaterials. Specific topics include bioelectronic materials, protein-polymer hybrids, and nanostructured proteins and polymers.B. D. Olsen

10.968 Seminar in Biomolecular EngineeringPrereq: Permission of instructorG (Fall, Spring)2-0-4 unitsCan be repeated for credit.

Covers research progress in the area of design, testing andmechanistic investigation of novel molecular systems forbiotechnological applications.H. D. Sikes

10.969 Molecular Engineering SeminarPrereq: Permission of instructorG (Fall, Spring)2-0-4 unitsCan be repeated for credit.

Seminar allows students to present their research to other studentsand staff. Research topics include molecular simulations techniquesand applications, and molecular engineering of pharmaceutical andbiopharmaceutical processes and formulations.B. L. Trout

10.970 Seminar in Molecular ComputationPrereq: Permission of instructorG (Fall, Spring)2-0-4 unitsCan be repeated for credit.

Seminar allows students to present their research to other studentsand staff. The research topics include computational chemistrytechniques, kinetics, and catalysis. Focus is on molecular-levelunderstanding of chemical change.W. H. Green

10.971 Seminar in Fluid Mechanics and Transport PhenomenaPrereq: Permission of instructorG (Fall, Spring)2-0-4 unitsCan be repeated for credit.

Seminar series on current research on Newtonian and non-Newtonian fluid mechanics and transport phenomena, andapplications to materials processing. Seminars given by guestspeakers and research students.P. S. Doyle, G. H. McKinley, J. W. Swan

10.972 Biochemical Engineering Research SeminarPrereq: Permission of instructorG (Fall, Spring)Not offered regularly; consult department2-0-4 unitsCan be repeated for credit.

Seminar allows students to present their research programs to otherstudents and staff. The research topics include fermentation andenzyme technology, mammalian and animal cell cultivation, andbiological product separation.D. I. C. Wang, C. L. Cooney

10.973 BioengineeringPrereq: Permission of instructorG (Fall, Spring)2-0-4 unitsCan be repeated for credit.

Seminar covering topics related to current research in theapplication of chemical engineering principles to biomedical scienceand biotechnology.C. K. Colton



10.974 Seminar in Chemical Engineering NanotechnologyPrereq: Permission of instructorG (Fall, Spring)2-0-4 unitsCan be repeated for credit.

Seminar covering topics related to current research inthe application of chemical engineering principles tonanotechnology.Limited to 30.M. S. Strano

10.975 Seminar in Polymer Science and EngineeringPrereq: Permission of instructorG (Fall, Spring)2-0-4 unitsCan be repeated for credit.

Research seminars, presented by students engaged in thesis workin the field of polymers and by visiting lecturers from industry andacademia.R. E. Cohen, P. T. Hammond, G. C. Rutledge

10.976 Process Design, Operations, and ControlPrereq: Permission of instructorG (Fall, Spring)2-0-4 unitsCan be repeated for credit.

Seminars on the state of the art in design, operations, and controlof processing systems, with emphasis on computer-based tools.Discussions guided by the research interests of participatingstudents. Topics include mathematical and numerical techniques,representational methodologies, and software development.P. I. Barton

10.977 Seminar in Electrocatalysis (New)Prereq: Permission of InstructorG (Fall, Spring)2-0-4 unitsCan be repeated for credit.

Seminar held every week, with presentations by graduate studentsand postdoctoral researchers on topics related to the molecularengineering of electrocatalysts. Emphasis on correlating atomic-level understanding of surfaces, their interactions with adsorbates,and the resulting impact on catalytic mechanisms.K. Manthiram

10.978 Seminar in Advanced Materials for Energy Applications(New)Prereq: Permission of instructorG (Fall, Spring)2-0-4 unitsCan be repeated for credit.

Students, postdocs, and visitors to present their work on synthesis,design, and characterization of polymeric and inorganic materialsfor applications related to membrane and adsorption-basedseparations.Z. P. Smith

10.981 Seminar in Colloid and Interface SciencePrereq: Permission of instructorG (Fall, Spring)2-0-4 unitsCan be repeated for credit.

Review of current topics in colloid and interface science. Topicsinclude statistical mechanics and thermodynamics of micellarsolutions, self-assembling systems, and microemulsions;solubilization of simple ions, amino acids, and proteins in reversedmicelles; enzymatic reactions in reversed micelles; phase equilibriain colloidal systems; interfacial phenomena in colloidal systems;biomedical aspects of colloidal systems.D. Blankschtein

10.982 Seminar in Experimental Colloid and Surface ChemistryPrereq: Permission of instructorG (Fall, Spring)2-0-4 unitsCan be repeated for credit.

In-depth discussion of fundamental physical relationshipsunderlying techniques commonly used in the study of colloidsand surfaces with a focus on recent advances and experimentalapplications. Topics have included the application of steady-state and time-resolved fluorescence spectroscopies, infraredspectroscopy, and scanning probe microscopies.T. A. Hatton



10.983 Reactive Processing and Microfabricated ChemicalSystemsPrereq: Permission of instructorG (Fall, Spring)2-0-4 unitsCan be repeated for credit.

Advanced topics in synthesis of materials through processesinvolving transport phenomena and chemical reactions. Chemicalvapor deposition, modeling, and experimental approachesto kinetics of gas phase and surface reactions, transportphenomena in complex systems, materials synthesis, andmaterials characterization. Design fabrication and applications ofmicrofabricated chemical systems. Seminars by graduate students,postdoctoral associates, participating faculty, and visiting lecturers.K. F. Jensen

10.984 Biomedical Applications of Chemical EngineeringPrereq: Permission of instructorG (Fall, Spring)2-0-4 unitsCan be repeated for credit.

Weekly seminar with lectures on current research by graduatestudents, postdoctoral fellows, and visiting scientists on topicsrelated to biomedical applications of chemical engineering.Specific topics include polymeric controlled release technology,extracorporal reactor design, biomedical polymers, bioengineeringaspects of pharmaceuticals, and biomaterials/tissue and cellinteractions.R. S. Langer

10.985 Seminar in Materials Systems EngineeringPrereq: Permission of instructorG (Fall, Spring)2-0-4 unitsCan be repeated for credit.

Focuses on the state of the art in the systems engineering ofmaterials products and materials manufacturing processes.Addresses topics such as pharmaceuticals manufacturing, polymericdrug delivery systems, and nano- and microstructured materials.Discussions guided by the research interests of participatingstudents. Includes techniques from applied mathematics andnumerical methods, multiscale systems analysis, and control theory.R. D. Braatz

10.987 Solid Thin Films and InterfacesPrereq: Permission of instructorG (Fall, Spring)2-0-4 unitsCan be repeated for credit.

Current research topics and fundamental issues relating to thedeposition and properties of solid thin films and interfaces.Emphasis on applying analytical techniques, such as solid-stateNMR, to explore the thermodynamics and kinetics of growth, defectformation, and structural modification incurred during film growthand post processing.K. K. Gleason

10.989 Seminar in BiotechnologyPrereq: Permission of instructorG (Fall, Spring)2-0-4 unitsCan be repeated for credit.

Research seminars, presented by graduate students and visitorsfrom industry and academia, covering a broad range of topics ofcurrent interest in biotechnology. Discussion focuses on genericquestions with potential biotechnological applications and the questfor solutions through a coordinated interdisciplinary approach.Gr. Stephanopoulos

10.990 Introduction to Chemical Engineering ResearchPrereq: NoneG (Fall)2-4-0 units

Introduction to research in chemical engineering by faculty ofchemical engineering department. Focus is on recent developmentsand research projects available to new graduate students.P. T. Hammond

10.991 Seminar in Chemical EngineeringPrereq: Permission of instructorG (Fall)2-0-4 unitsCan be repeated for credit.

For students working on doctoral theses.P. T. Hammond

10.992 Seminar in Chemical EngineeringPrereq: Permission of instructorG (Spring)2-0-4 unitsCan be repeated for credit.

For students working on doctoral theses.K. F. Jensen



10.994 Molecular BioengineeringPrereq: Permission of instructorG (Fall, Spring)2-0-4 unitsCan be repeated for credit.

Presentations and discussion by graduate students, postdoctoralfellows, and visiting scientists of current literature and researchon the engineering of protein biopharmaceuticals. Topics includecombinatorial library construction and screening strategies,antibody engineering, gene therapy, cytokine engineering, andimmunotherapy engineering strategies.K. D. Wittrup

10.995 Cellular and Metabolic EngineeringPrereq: Permission of instructorG (Fall, Spring)2-0-4 unitsCan be repeated for credit.

Graduate students, postdoctoral fellows, visiting scientists, andguest industrial practitioners to present their own research andhighlight important advances from the literature in biochemicaland bioprocess engineering. Topics of interest include metabolicengineering, novel microbial pathway design and optimization,synthetic biology, and applications of molecular biology tobioprocess development.K. J. Prather

10.997 Theoretical and Computational Immunology SeminarPrereq: Permission of instructorG (Fall, Spring)2-0-4 unitsCan be repeated for credit.

Presentations and discussions of current literature and researchin theoretical and computational immunology. Topics include Tcell biology, cell-cell recognition in immunology, polymers andmembranes, and statistical mechanics.Arup K. Chakraborty

10.998 Seminar in Crystallization Science and TechnologyPrereq: NoneG (Fall, Spring)2-0-4 unitsCan be repeated for credit.

Focuses on current topics related to crystallization science andtechnology in the chemical, pharmaceutical and food industries.Discusses fundamental work on nucleation, polymorphism, impuritycrystal interactions and nano-crystal formation, along with industrialapplications of crystallization.A. S. Myerson

10.EPE UPOP Engineering Practice ExperienceEngineering School-Wide Elective Subject.Offered under: 1.EPE, 2.EPE, 3.EPE, 6.EPE, 10.EPE, 16.EPE, 22.EPEPrereq: 2.EPW or permission of instructorU (Fall, Spring)0-0-1 units

See description under subject 2.EPE.Staff

10.EPW UPOP Engineering Practice WorkshopEngineering School-Wide Elective Subject.Offered under: 1.EPW, 2.EPW, 3.EPW, 6.EPW, 10.EPW, 16.EPW,20.EPW, 22.EPWPrereq: NoneU (Fall, IAP)1-0-0 units

See description under subject 2.EPW.Enrollment limited.Staff

10.S94 Special Problems in Chemical EngineeringPrereq: Permission of instructorU (Fall, Spring)Units arrangedCan be repeated for credit.

Focuses on problem of current interest not covered in regularcurriculum; topic varies from year to year.Staff

10.S95 Special Problems in Chemical EngineeringPrereq: Permission of instructorG (Fall, Spring)Units arrangedCan be repeated for credit.

Focuses on problem of current interest not covered in regularcurriculum; topic varies from year to year.Staff

10.THG Graduate ThesisPrereq: Permission of instructorG (Fall, IAP, Spring, Summer)Units arrangedCan be repeated for credit.

Program of research leading to the writing of an SM, PhD, or ScDthesis; to be arranged by the student and appropriate MIT facultymember.D. Blankschtein



10.THU Undergraduate ThesisPrereq: NoneU (Fall, IAP, Spring, Summer)Units arrangedCan be repeated for credit.

Program of research leading to writing an SB thesis; topic arrangedbetween student and MIT faculty member.B. S. Johnston

10.UR Undergraduate ResearchPrereq: NoneU (Fall, IAP, Spring, Summer)Units arranged [P/D/F]Can be repeated for credit.

Opportunity for participation in the work of a research group, orfor special investigation in a particular field. Topic and hours to fitindividual requirements.B. S. Johnston

10.URG Undergraduate ResearchPrereq: NoneU (Fall, IAP, Spring, Summer)Units arrangedCan be repeated for credit.

Opportunity for participation in a research group, or for specialinvestigation in a particular field. Topic and hours to fit individualrequirements.B. S. Johnston

department of chemical engineering - welcome! <...

Documents