department of medicine anderson me, wehrens xht. oxidized camkii (ca 2+/calmodulin-dependent protein...

DEPARTMENT OF MEDICINE Annual Research Report

July 2017 – June 2018

TABLE OF CONTENT

Cardiovascular Research Endocrinology, Diabetes, and Metabolism Epidemiology and Population Sciences Gastroenterology and Hepatology General Internal Medicine Geriatrics Health Services Research Hematology-Oncology Immunology, Allergy and Rheumatology Infectious Diseases Nephrology Pulmonary, Critical Care and Sleep Medicine Transition Medicine

Cardiovascular Research

JULY 2017– JUNE 2018

Section of Cardiovascular Research Department of Medicine, Baylor College of Medicine (1 July 2017–30 June 2018) A. Publications 1. Power MC, Rawlings A, Sharrett AR, Bandeen-Roche K, Coresh J, Ballantyne CM,

Pokharel Y, Michos ED, Penman A, Alonso A, Knopman D, Mosley TH, Gottesman RF. Association of midlife lipids with 20-year cognitive change: a cohort study. Alzheimers Dement 2018;14:167–177.

2. Fashanu OE, Norby FL, Aguilar D, Ballantyne CM, Hoogeveen RC, Chen LY, Soliman EZ, Alonso A, Folsom AR. Galectin-3 and incidence of atrial fibrillation: the Atherosclerosis Risk in Communities (ARIC) study. Am Heart J 2017;192:19–25.

3. Navar AM, Wang TY, Li S, Robinson JG, Goldberg AC, Virani S, Roger VL, Wilson PWF, Elassal J, Lee LV, Peterson ED. Lipid management in contemporary community practice: Results from the Provider Assessment of Lipid Management (PALM) Registry. Am Heart J 2017;193:84–92.

4. Yong CM, Liu Y, Apruzzese P, Doros G, Cannon CP, Maddox TM, Gehi A, Hsu JC, Lubitz SA, Virani S, Turakhia MP; ACC PINNACLE Investigators. Association of insurance type with receipt of oral anticoagulation in insured patients with atrial fibrillation: a report from the American College of Cardiology NCDR PINNACLE registry. Am Heart J 2018;195:50–59.

5. Hess PL, Kennedy K, Cowherd M, Virani SS, Masoudi FA, Navar AM, Yeh RW, Ho PM, Maddox TM. Implications of the FDA approval of PCSK9 inhibitors and FOURIER results for contemporary cardiovascular practice: an NCDR Research to Practice (R2P) project. Am Heart J 2018;195:151–152.

6. Garg PK, Bartz TM, Norby FL, Jorgensen NW, McClelland RL, Ballantyne CM, Chen LY, Gottdiener JS, Greenland P, Hoogeveen R, Jenny NS, Kizer JR, Rosenson RS, Soliman EZ, Cushman M, Alonso A, Heckbert SR. Association of lipoprotein-associated phospholipase A2 and risk of incident atrial fibrillation: findings from 3 cohorts. Am Heart J 2018;197:62–69.

7. Lowenstern A, Li S, Navar AM, Virani S, Lee LV, Louie MJ, Peterson ED, Wang TY. Does clinician-reported lipid guideline adoption translate to guideline-adherent care? An evaluation of the Patient and Provider Assessment of Lipid Management (PALM) registry. Am Heart J 2018;200:118–124.

8. Ballantyne CM, Shah S, Sapre A, Ashraf TB, Tobias SC, Sahin T, Ye P, Dong Y, Sheu WH, Kang DH, Ferreira Rossi PR, Moiseeva Y, Briones IR, Johnson-Levonas AO, Mitchel YB. A multiregional, randomized evaluation of the lipid-modifying efficacy and tolerability of anacetrapib added to ongoing statin therapy in patients with hypercholesterolemia or low high-density lipoprotein cholesterol. Am J Cardiol 2017;120:569–576.

9. Khan MR, Kayani WT, Ahmad W, Hira RS, Virani SS, Hamzeh I, Jneid H, Lakkis N, Alam M. Meta-analysis of comparison of 5-year outcomes of percutaneous coronary intervention versus coronary artery bypass grafting in patients with unprotected left main coronary artery in the era of drug-eluting stents. Am J Cardiol 2017;120:1514–1520.

10. Fretz A, McEvoy JW, Rebholz CM, Ndumele CE, Florido R, Hoogeveen RC, Ballantyne CM, Selvin E. Relation of lifestyle factors and Life's Simple 7 score to temporal reduction in troponin levels measured by a high-sensitivity assay (from the Atherosclerosis Risk in Communities Study). Am J Cardiol 2018;121:430–436.

11. McCullough PA, Ballantyne CM, Sanganalmath SK, Langslet G, Baum SJ, Shah PK, Koren A, Mandel J, Davidson MH. Efficacy and safety of alirocumab in high-risk patients with clinical atherosclerotic cardiovascular disease and/or heterozygous familial hypercholesterolemia (from 5 placebo-controlled ODYSSEY trials). Am J Cardiol 2018;121:940–948.

12. Tibuakuu M, Kianoush S, DeFilippis AP, McEvoy JW, Zhao D, Guallar E, Ballantyne CM, Hoogeveen RC, Blaha MJ, Michos ED. Usefulness of lipoprotein-associated phospholipase A2 activity and C-reactive protein in identifying high-risk smokers for atherosclerotic cardiovascular disease (from the Atherosclerosis Risk in Communities Study). Am J Cardiol 2018;121:1056–1064.

13. Trial J, Cieslik KA. Changes in cardiac resident fibroblast physiology and phenotype in aging. Am J Physiol Heart Circ Physiol 2018 [Epub ahead of print].

14. Vart P, Matsushita K, Rawlings AM, Selvin E, Crews DC, Ndumele CE, Ballantyne CM, Heiss G, Kucharska-Newton A, Szklo M, Coresh J. SES, heart failure, and N-terminal pro-B-type natriuretic peptide: the Atherosclerosis Risk in Communities Study. Am J Prev Med 2018;54:229–236.

15. Tang W, Yao L, Hoogeveen RC, Alonso A, Couper DJ, Lutsey PL, Steenson CC, Guan W, Hunter DW, Lederle FA, Folsom AR. The association of biomarkers of inflammation and extracellular matrix degradation with the risk of abdominal aortic aneurysm: the ARIC Study. Angiology 2018 [Epub ahead of print].

16. Smith MW, Brown C, Virani SS, Weir CR, Petersen LA, Kelly N, Akeroyd J, Garvin JH. Incorporating guideline adherence and practice implementation issues into the design of decision support for beta-blocker titration for heart failure. Appl Clin Inform 2018;9:478–489.

17. Vaughan EM, Moreno JP, Hyman D, Chen TA, Foreyt JP. Efficacy of oral versus insulin therapy for newly diagnosed diabetes in low-income settings. Arch Gen Intern Med 2017;1:17–22.

18. Lockyer P, Mao H, Fan Q, Li L, LYu-Lee L, Eissa NT, Patterson C, Xie L, Pi X. LRP1-dependent BMPER signaling regulates lipopolysaccharide-induced vascular inflammation. Arterioscler Thromb Vasc Biol 2017;37:1524–1535.

19. Zhou Y, Cardenas JC, Qin S, Trist A, Li T, Garcia R, Cruz MA, Moake J, Tian Q, Frazier O, Dong JF, Nascimbene A. quantification of von Willebrand factor cleavage by ADAMTS-13 in patients supported by left ventricular assist devices. ASAIO J 2017;63:849–853.

20. Agarwala A, Pokharel Y, Saeed A, Sun W, Virani SS, Nambi V, Ndumele C, Shahar E, Heiss G, Boerwinkle E, Konety S, Hoogeveen RC, Ballantyne CM. The association of lipoprotein(a) with incident heart failure hospitalization: Atherosclerosis Risk in Communities study. Atherosclerosis 2017;262:131–137.

21. Puri R, Ballantyne CM, Hoogeveen RC, Shao M, Barter P, Libby P, Chapman MJ, Erbel R, Arsenault BJ, Raichlen JS, Nissen SE, Nicholls SJ. Lipoprotein(a) and coronary atheroma progression rates during long-term high-intensity statin therapy: Insights from SATURN. Atherosclerosis 2017;263:137–144.

22. Amrock SM, Duell PB, Knickelbine T, Martin SS, O'Brien EC, Watson KE, Mitri J, Kindt I, Shrader P, Baum SJ, Hemphill LC, Ahmed CD, Andersen RL, Kullo IJ, McCann D, Larry JA, Murray MF, Fishberg R, Guyton JR, Wilemon K, Roe MT, Rader DJ, Ballantyne CM, Underberg JA, Thompson P, Duffy D, Linton MF, Shapiro MD, Moriarty PM, Knowles JW, Ahmad ZS. Health disparities among adult patients with a phenotypic diagnosis of familial hypercholesterolemia in the CASCADE-FHTM patient registry. Atherosclerosis 2017;267:19–26.

23. Garg PK, Norby FL, Polfus LM, Boerwinkle E, Gibbs RA, Grove ML, Folsom AR, Garimella PS, Matsushita K, Hoogeveen RC, Ballantyne CM. Lipoprotein-associated

phospholipase A2 and risk of incident peripheral arterial disease: findings from the Atherosclerosis Risk in Communities study (ARIC). Atherosclerosis 2017;268:12–18.

24. Kubota Y, Folsom AR, Ballantyne CM, Tang W. Lipoprotein(a) and abdominal aortic aneurysm risk: the Atherosclerosis Risk in Communities study. Atherosclerosis 2017;268:63–67.

25. Valero-Elizondo J, Hong JC, Spatz ES, Salami JA, Desai NR, Rana JS, Khera R, Virani SS, Blankstein R, Blaha MJ, Nasir K. Persistent socioeconomic disparities in cardiovascular risk factors and health in the United States: Medical Expenditure Panel Survey 2002-2013. Atherosclerosis 2018;269:301–305.

26. Ogunmoroti O, Michos ED, Aronis KN, Salami JA, Blankstein R, Virani SS, Spatz ES, Allen NB, Rana JS, Blumenthal RS, Veledar E, Szklo M, Blaha MJ, Nasir K. Life's Simple 7 and the risk of atrial fibrillation: the Multi-Ethnic Study of Atherosclerosis. Atherosclerosis 2018;275:174–181.

27. Ballantyne CM, Banach M, Mancini GBJ, Lepor NE, Hanselman JC, Zhao X, Leiter LA. Efficacy and safety of bempedoic acid added to ezetimibe in statin-intolerant patients with hypercholesterolemia: a randomized, placebo-controlled study. Atherosclerosis 2018 [Epub ahead of print].

28. Vijayan KV. Myosin IIa signal von Willebrand factor release. Blood 2018;131:592–593. 29. White DL, Hoogeveen RC, Chen L, Richardson P, Ravishankar M, Shah P, Tinker L,

Rohan T, Whitsel EA, El-Serag HB, Jiao L. A prospective study of soluble receptor for advanced glycation end products and adipokines in association with pancreatic cancer in postmenopausal women. Cancer Med 2018;7:2180–2191.

30. Saeed A, Ballantyne CM. Bempedoic acid (ETC-1002): a current review. Cardiol Clin 2018;36:257–264.

31. Wang Q, Quick AP, Cao S, Reynolds J, Chiang DY, Beavers D, Li N, Wang G, Rodney GG, Anderson ME, Wehrens XHT. Oxidized CaMKII (Ca2+/calmodulin-dependent protein kinase II) is essential for ventricular arrhythmia in a mouse model of Duchenne muscular dystrophy. Circ Arrhythm Electrophysiol 2018;11:e005682.

32. Navar AM, Peterson ED, Li S, Robinson JG, Roger VL, Goldberg AC, Virani S, Wilson PWF, Nanna MG, Lee LV, Elassal J, Wang TY. Prevalence and management of symptoms associated with statin therapy in community practice: insights from the PALM (Patient and Provider Assessment of Lipid Management) Registry. Circ Cardiovasc Qual Outcomes 2018;11:e004249.

33. Virani SS, Kennedy KF, Akeroyd JM, Morris PB, Bittner VA, Masoudi FA, Stone NJ, Petersen LA, Ballantyne CM. Variation in lipid-lowering therapy use in patients with low-density lipoprotein cholesterol ≥190 mg/dl: insights from the National Cardiovascular Data Registry–Practice Innovation and Clinical Excellence Registry. Circ Cardiovasc Qual Outcomes 2018;11:e004652.

34. Harrington JL, Ayers C, Berry JD, Omland T, Pandey A, Seliger SL, Ballantyne CM, Kulinski J, deFilippi CR, de Lemos JA. Sedentary behavior and subclinical cardiac injury: results from the Dallas Heart Study. Circulation 2017;136:1451–1453.

35. Nambi V, Deswal A, Ballantyne CM. Prevention of "failure": is it a failure of prevention? Circulation 2018;137:106–108.

36. Khera R, Hong JC, Saxena A, Arrieta A, Virani SS, Blankstein R, de Lemos JA, Krumholz HM, Nasir K. Burden of catastrophic health expenditures for acute myocardial infarction and stroke among uninsured in the United States. Circulation 2018;137:408–410.

37. Florido R, Kwak L, Lazo M, Nambi V, Ahmed HM, Hegde SM, Gerstenblith G, Blumenthal RS, Ballantyne CM, Selvin E, Folsom AR, Coresh J, Ndumele CE. Six-year changes in physical activity and the risk of incident heart failure: the Atherosclerosis Risk in Communities (ARIC) Study. Circulation 2018;137:2142–2151.

38. Benjamin EJ, Virani SS, Callaway CW, Chamberlain AM, Chang AR, Cheng S, Chiuve SE, Cushman M, Delling FN, Deo R, de Ferranti SD, Ferguson JF, Fornage M, Gillespie C, Isasi CR, Jiménez MC, Jordan LC, Judd SE, Lackland D, Lichtman JH, Lisabeth L, Liu S, Longenecker CT, Lutsey PL, Mackey JS, Matchar DB, Matsushita K, Mussolino ME, Nasir K, O'Flaherty M, Palaniappan LP, Pandey A, Pandey DK, Reeves MJ, Ritchey MD, Rodriguez CJ, Roth GA, Rosamond WD, Sampson UKA, Satou GM, Shah SH, Spartano NL, Tirschwell DL, Tsao CW, Voeks JH, Willey JZ, Wilkins JT, Wu JH, Alger HM, Wong SS, Muntner P; American Heart Association Council on Epidemiology and Prevention Statistics Committee and Stroke Statistics Subcommittee. Heart disease and stroke statistics—2018 update: a report from the American Heart Association. Circulation 2018;137:e67–e492.

39. Yao C, Veleva T, Scott L Jr, Cao S, Li L, Chen G, Jeyabal P, Pan X, Alsina KM, Abu-Taha I, Ghezelbash S, Reynolds CL, Shen YH, LeMaire SA, Schmitz W, Müller FU, El-Armouche A, Eissa NT, Beeton C, Nattel S, Wehrens XHT, Dobrev D, Li N. Enhanced cardiomyocyte NLRP3 inflammasome signaling promotes atrial fibrillation. Circulation 2018 [Epub ahead of print].

40. Rehman H, Akeroyd JM, Ramsey D, Ahmed ST, Merchant AT, Navaneethan SD, Petersen LA, Virani SS. Facility-level variation in diabetes and blood pressure control in patients with diabetes: Findings from the Veterans Affairs national database. Clin Cardiol 2017;40:1055–1060.

41. Ndumele CE, Cobb L, Lazo M, Bello NA, Shah A, Nambi V, Blumenthal RS, Gerstenblith G, Solomon SD, Ballantyne CM, Selvin E, Coresh J. Weight history and subclinical myocardial damage. Clin Chem 2018;64:201–209.

42. Lo GH, McAlindon TE, Katz JN, Driban JB, Price LL, Eaton CB, Petersen NJ, Ballantyne CM, Suarez-Almazor ME. Systolic and pulse pressure associate with incident knee osteoarthritis: data from the Osteoarthritis Initiative. Clin Rheumatol 2017;36:2121–2128.

43. Singh J, Brunner G, Morrisett JD, Ballantyne CM, Lumsden AB, Shah DJ, Decuzzi P. Patient-specific flow descriptors and normalized wall index in peripheral artery disease: a preliminary study. Comput Methods Biomech Biomed Eng Imaging Vis 2018;6:119–127.

44. Ahmed ST, Rehman H, Akeroyd JM, Alam M, Shah T, Kalra A, Virani SS. Premature coronary heart disease in South Asians: burden and determinants. Curr Atheroscler Rep 2018;20:6.

45. Saeed A, Dabhadkar K, Virani SS, Jones PH, Ballantyne CM, Nambi V. Cardiovascular disease prevention: training opportunities, the challenges, and future directions. Curr Atheroscler Rep 2018;20:35. [Correction: Curr Atheroscler Rep 2018;20:42]

46. Kampangkaew J, Pickett S, Nambi V. Advances in the management of dyslipidemia. Curr Opin Cardiol 2017;32:348–355.

47. LeBlanc ES, Pratley RE, Dawson-Hughes B, Staten MA, Sheehan PR, Lewis MR, Peters A, Kim SH, Chatterjee R, Aroda VR, Chadha C, Neff LM, Brodsky IG, Rosen C, Desouza CV, Foreyt JP, Hsia DS, Johnson KC, Raskin P, Kashyap SR, O'Neil P, Phillips LS, Rasouli N, Liao EP, Robbins DC, Pittas AG; D2d Research Group. Baseline characteristics of the Vitamin D and Type 2 Diabetes (D2d) Study: a contemporary prediabetes cohort that will inform diabetes prevention efforts. Diabetes Care 2018 [Epub ahead of print].

48. Vaughan EM, Johnston CA, Cardenas VJ, Moreno JP, Foreyt JP. Integrating CHWs as part of the team leading diabetes group visits: a randomized controlled feasibility study. Diabetes Educ 2017;43:589–599.

49. Andersen A, Foreyt J, Maine M, Cohn L. Eating disorders: a 25-year perspective. Eat Disord 2017;25:436–447.

50. Lai YC, Li N, Lawrence W, Wang S, Levine A, Burchhardt DM, Pautler RG, Valderrábano M, Wehrens XH, Anderson AE. Myocardial remodeling and susceptibility to ventricular tachycardia in a model of chronic epilepsy. Epilepsia Open 2018;3:213–223.

51. Matsushita K, Kwak L, Yang C, Pang Y, Ballew SH, Sang Y, Hoogeveen RC, Jaar BG, Selvin E, Ballantyne CM, Sharrett AR, Folsom AR, Heiss G, Coresh J, Hirsch AT. High-sensitivity cardiac troponin and natriuretic peptide with risk of lower-extremity peripheral artery disease: the Atherosclerosis Risk in Communities (ARIC) Study. Eur Heart J 2018 [Epub ahead of print].

52. Angelini A, Pi X, Xie L. Dioxygen and metabolism; dangerous liaisons in cardiac function and disease. Front Physiol 2017 Dec 12;8:1044.

53. Johnston CA, Moreno JP, Reichek B, Foreyt JP. Dissemination of a school-based obesity intervention for Mexican Americans: a randomized controlled trial. Health Behavior Policy Review 2017;4:454–466.

54. Saeed A, Virani SS. Lipoprotein(a) and cardiovascular disease: current state and future directions for an enigmatic lipoprotein. Front Biosci (Landmark Ed) 2018;23:1099–1112.

55. Klipp RC, Li N, Wang Q, Word TA, Sibrian-Vazquez M, Strongin RM, Wehrens XHT, Abramson JJ. EL20, a potent antiarrhythmic compound, selectively inhibits calmodulin-deficient ryanodine receptor type 2. Heart Rhythm 2018;15:578–586.

56. Kocarnik JM, Richard M, Graff M, Haessler J, Bien S, Carlson C, Carty CL, Reiner AP, Avery CL, Ballantyne CM, LaCroix AZ, Assimes TL, Barbalic M, Pankratz N, Tang W, Tao R, Chen D, Talavera GA, Daviglus ML, Chirinos DA, Pereira R, Nishimura K, Bu ková P, Best LG, Luis Ambite J, Cheng I, Crawford DC, Hindorff LA, Fornage M, Heiss G, North KE, Haiman CA, Peters U, Le Marchand L, Kooperberg C. Discovery, fine-mapping, and conditional analyses of genetic variants associated with C-reactive protein in multiethnic populations using the Metabochip in the Population Architecture using Genomics and Epidemiology (PAGE) study. Hum Mol Genet 2018 [Epub ahead of print].

57. Samad Z, Merchant AT, Narula JS, Virani SS. "All hands on deck": an imperative for tackling hypertension in South Asia. Indian Heart J 2017;69:430–431.

58. Arenas de Larriva AP, Norby FL, Chen LY, Soliman EZ, Hoogeveen RC, Arking DE, Loehr LR, Alonso A. Circulating ceruloplasmin, ceruloplasmin-associated genes, and the incidence of atrial fibrillation in the Atherosclerosis Risk in Communities study. Int J Cardiol 2017;241:223–228.

59. Chelu MG, Li N. Biomarkers (plasma trimethylamine-N-oxide) to predict atrial fibrillation: are we there yet? Int J Cardiol 2018 [Epub ahead of print].

60. Yousif A, Addison D, Lakkis N, Rosengart T, Virani SS, Birnbaum Y, Alam M. Use of cardiopulmonary pump support during coronary artery bypass grafting in the high-risk: a meta-analysis. Ir J Med Sci 2018;187:369–377.

61. Lloyd-Jones DM, Morris PB, Ballantyne CM, Birtcher KK, Daly DD Jr, DePalma SM, Minissian MB, Orringer CE, Smith SC Jr. 2017 focused update of the 2016 ACC Expert Consensus Decision Pathway on the Role of Non-Statin Therapies for LDL-Cholesterol Lowering in the Management of Atherosclerotic Cardiovascular Disease Risk: a report of the American College of Cardiology Task Force on Expert Consensus Decision Pathways. J Am Coll Cardiol 2017;70:1785–1822.

62. Nambi V, Bhatt DL. Primary prevention of atherosclerosis: time to take a selfie? J Am Coll Cardiol 2017;70:2992–2994.

63. Saeed A, Nambi V, Sun W, Virani SS, Taffet G, Deswal A, Selvin E, Matsushita K, Wagenknecht LE, Hoogeveen R, Coresh J, de Lemos JA, Ballantyne CM. Short-term global cardiovascular disease risk prediction in older adults. J Am Coll Cardiol 2018;71:2527–2536.

64. Navaneethan SD, Virani SS. Omega-3 fatty acids (fish oil) supplementation and albuminuria: not a slam dunk. J Am Heart Assoc 2017;6:e006020.

65. van Capelleveen JC, Bochem AE, Boekholdt SM, Mora S, Hoogeveen RC, Ballantyne CM, Ridker PM, Sun W, Barter PJ, Tall AR, Zwinderman AH, Kastelein JJP, Wareham NJ, Khaw KT, Hovingh GK. Association of high-density lipoprotein-cholesterol versus apolipoprotein A-I with risk of coronary heart disease: the European Prospective Investigation into Cancer-Norfolk Prospective Population Study, the Atherosclerosis Risk in Communities Study, and the Women's Health Study. J Am Heart Assoc 2017;6:e006636.

66. Aronis KN, Zhao D, Hoogeveen RC, Alonso A, Ballantyne CM, Guallar E, Jones SR, Martin SS, Nazarian S, Steffen BT, Virani SS, Michos ED. Associations of lipoprotein(a) levels with incident atrial fibrillation and ischemic stroke: the ARIC (Atherosclerosis Risk in Communities) Study. J Am Heart Assoc 2017;6:e007372.

67. Salami JA, Warraich HJ, Valero-Elizondo J, Spatz ES, Desai NR, Rana JS, Virani SS, Blankstein R, Khera A, Blaha MJ, Blumenthal RS, Katzen BT, Lloyd-Jones D, Krumholz HM, Nasir K. National trends in nonstatin use and expenditures among the US adult population from 2002 to 2013: Insights From Medical Expenditure Panel Survey. J Am Heart Assoc 2018;7:e007132.

68. Singh J, Valero-Elizondo J, Salami JA, Warraich HJ, Ogunmoroti O, Spatz ES, Desai N, Rana JS, Virani SS, Blankstein R, Blaha MJ, Nasir K. Favorable modifiable cardiovascular risk profile is associated with lower healthcare costs among cancer patients: the 2012-2013 Medical Expenditure Panel Survey. J Am Heart Assoc 2018;7:e007874.

69. Basra SS, Wang TY, Simon DN, Chiswell K, Virani SS, Alam M, Nambi V, Denktas AE, Deswal A, Bozkurt B, Ballantyne CM, Peterson ED, Jneid H. Ticagrelor use in acute myocardial infarction: insights from the National Cardiovascular Data Registry. J Am Heart Assoc 2018;7:e008125.

70. Kayani WT, Ballantyne CM. Improving outcomes after myocardial infarction in the US population. J Am Heart Assoc 2018;7:e008407.

71. Nanna MG, Navar AM, Wang TY, Mi X, Virani SS, Louie MJ, Lee LV, Goldberg AC, Roger VL, Robinson J, Peterson ED. Statin use and adverse effects among adults >75 years of age: insights from the Patient and Provider Assessment of Lipid Management (PALM) Registry. J Am Heart Assoc 2018;7:e008546.

72. Juraschek SP, Daya N, Appel LJ, Miller ER III, McEvoy JW, Matsushita K, Ballantyne CM, Selvin E. Orthostatic hypotension and risk of clinical and subclinical cardiovascular disease in middle-aged adults. J Am Heart Assoc 2018;7:e008884.

73. Miedema MD, Dardari ZA, Kianoush S, Virani SS, Yeboah J, Knickelbine T, Sandfort V, Rodriguez CJ, Nasir K, Blaha MJ. Statin eligibility, coronary artery calcium, and subsequent cardiovascular events according to the 2016 United States Preventive Services Task Force (USPSTF) Statin Guidelines: MESA (Multi-Ethnic Study of Atherosclerosis). J Am Heart Assoc 2018;7:e008920.

74. Pradhan S, Khatlani T, Nairn AC, Vijayan KV. The heterotrimeric G protein Gβ1 interacts with the catalytic subunit of protein phosphatase 1 and regulates G protein coupled receptor signaling in platelets. J Biol Chem 2017;292:13133–13142.

75. Suh JH, Lai L, Nam D, Kim J, Jo J, Taffet GE, Kim E, Kaelber JT, Lee HK, Entman ML, Cooke JP, Reineke EL. Steroid receptor coactivator-2 (SRC-2) coordinates cardiomyocyte paracrine signaling to promote pressure overload-induced angiogenesis. J Biol Chem 2017;292:21643-21652.

76. Johnson KC, Bray GA, Cheskin LJ, Clark JM, Egan CM, Foreyt JP, Garcia KR, Glasser S, Greenway FL, Gregg EW, Hazuda HP, Hergenroeder A, Hill JO, Horton ES, Jakicic JM, Jeffery RW, Kahn SE, Knowler WC, Lewis CE, Miller M, Montez MG, Nathan DM,

Patricio JL, Peters AL, Pi-Sunyer X, Pownall HJ, Reboussin D, Redmon JB, Steinberg H, Wadden TA, Wagenknecht LE, Wing RR, Womack CR, Yanovski SZ, Zhang P, Schwartz AV; Look AHEAD Study Group. The effect of intentional weight loss on fracture risk in persons with diabetes: results from the Look AHEAD randomized clinical trial. J Bone Miner Res 2017;32:2278–2287.

77. Yao H, He G, Chen C, Yan S, Lu L, Song L, Vijayan KV, Li Q, Xiong L, Miao X, Deng X. PAI1: a novel PP1-interacting protein that mediates human plasma’s anti-apoptotic effect in endothelial cells. J Cell Mol Med 2017;21:2068–2076.

78. Perrard XYD, Lian Z, Bobotas G, Dicklin M, Maki K, Wu H. Effects of n-3 fatty acid treatment on monocyte phenotypes in humans with hypertriglyceridemia. J Clin Lipidol 2017;11:1361–1371.

79. Pokharel Y, Tang Y, Bhardwaj B, Patel KK, Qintar M, O'Keefe JH Jr, Kulkarni KR, Jones PH, Martin SS, Virani SS, Spertus JA. Association of low-density lipoprotein pattern with mortality after myocardial infarction: Insights from the TRIUMPH study. J Clin Lipidol 2017;11:1458–1470.e4.

80. Bucheit JD, Helsing H, Nadpara P, Virani SS, Dixon DL. Clinical pharmacist understanding of the 2013 American College of Cardiology/American Heart Association cholesterol guideline. J Clin Lipidol 2018;12:367–374.e3.

81. Saeed A, Virani SS, Jones PH, Ballantyne CM, Nambi V. Case reports of proprotein convertase subtilisin kexsin 9 (PCSK9) inhibition non-response. J Clin Lipidol 2018 [Epub ahead of print].

82. Navaneethan SD, Schold JD, Walther CP, Arrigain S, Jolly SE, Virani SS, Winkelmayer WC, Nally JV Jr. High-density lipoprotein cholesterol and causes of death in chronic kidney disease. J Clin Lipidol 2018 [Epub ahead of print].

83. Federspiel JJ, Sueta CA, Kucharska-Newton AM, Beyhaghi H, Zhou L, Virani SS, Rodgers JE, Chang PP, Stearns SC. Antihypertensive adherence and outcomes among community-dwelling Medicare beneficiaries: the Atherosclerosis Risk in Communities Study. J Eval Clin Pract 2018;24:48–55.

84. Woodard LD, Adepoju OE, Amspoker AB, Virani SS, Ramsey DJ, Petersen LA, Jones LA, Kiefer L, Mehta P, Naik AD. Impact of patient-centered medical home implementation on diabetes control in the Veterans Health Administration. J Gen Intern Med 2018 [Epub ahead of print].

85. Houston DK, Neiberg RH, Miller ME, Hill JO, Jakicic JM, Johnson KC, Gregg EW, Hubbard VS, Pi-Sunyer X, Rejeski WJ, Wing RR, Bantle JP, Beale E, Berkowitz RI, Cassidy-Begay M, Clark JM, Coday M, Delahanty LM, Dutton G, Egan C, Foreyt JP, Greenway FL, Hazuda HP, Hergenroeder A, Horton ES, Jeffery RW, Kahn SE, Kure A, Knowler WC, Lewis CE, Martin CK, Michaels S, Montez MG, Nathan DM, Patricio J, Peters A, Pownall H, Regensteiner J, Steinburg H, Wadden TA, White K, Yanovski SZ, Zhang P, Kritchevsky SB. Physical function following a long-term lifestyle intervention among middle aged and older adults with type 2 diabetes: the Look AHEAD Study. J Gerontol A Biol Sci Med Sci 2017 [Epub ahead of print].

86. Cieslik KA, Sekhar RV, Granillo A, Reddy A, Medrano G, Pena Heredia C, Entman ML, Hamilton DJ, Li S, Reineke E, Gupte AA, Zhang A, Taffet GE. Improved cardiovascular function in old mice after N-acetyl cysteine and glycine supplemented diet: inflammation and mitochondrial factors. J Gerontol A Biol Sci Med Sci 2018 [Epub ahead of print].

87. Lam F, Da Q, Guillory B, Cruz MA. The binding of recombinant vimentin to P-selectin blocks neutrophil capture and rolling on platelets and endothelium. J Immunol 2018;200:1718–1726.

88. Cieslik KA, Trial J, Entman ML. Aicar treatment reduces interstitial fibrosis in aging mice: suppression of the inflammatory fibroblast. J Mol Cell Cardiol 2017;111:81–85.

89. Vaughan EM, Johnston CA, Hyman DJ, Hernandez DC, Hemmige V, Foreyt JP. Dual therapy appears superior to monotherapy for low-income individuals with newly diagnosed type 2 diabetes. J Prim Care Community Health 2017;8:305–311.

90. Brinton EA, Ballantyne CM, Guyton JR, Philip S, Doyle RT Jr, Juliano RA, Mosca L. Lipid effects of icosapent ethyl in women with diabetes mellitus and persistent high triglycerides on statin treatment: ANCHOR trial subanalysis. J Womens Health (Larchmt) 2018 [Epub ahead of print].

91. Hira RS, Vemulapalli S, Li Z, McCabe JM, Rumsfeld JS, Kapadia SR, Alam M, Jneid H, Don C, Reisman M, Virani SS, Kleiman NS. Trends and outcomes of off-label use of transcatheter aortic valve replacement: insights from the NCDR STS/ACC TVT Registry. JAMA Cardiol 2017;2:846–854.

92. Arrieta A, Hong JC, Khera R, Virani SS, Krumholz HM, Nasir K. Updated cost-effectiveness assessments of PCSK9 inhibitors from the perspectives of the health system and private payers: insights derived from the FOURIER Trial. JAMA Cardiol 2017;2:1369–1374.

93. Schwartz GG, Ballantyne CM, Barter PJ, Kallend D, Leiter LA, Leitersdorf E, McMurray JJV, Nicholls SJ, Olsson AG, Shah PK, Tardif JC, Kittelson J. Association of lipoprotein(a) with risk of recurrent ischemic events following acute coronary syndrome: analysis of the dal-Outcomes randomized clinical trial. JAMA Cardiol 2018;3:164–168.

94. Vazir A, Claggett B, Cheng S, Skali H, Shah A, Aguilar D, Ballantyne CM, Vardeny O, Solomon SD. Association of resting heart rate and temporal changes in heart rate with outcomes in participants of the Atherosclerosis Risk in Communities Study. JAMA Cardiol 2018;3:200–206.

95. Nanna MG, Navar AM, Zakroysky P, Xiang Q, Goldberg AC, Robinson J, Roger VL, Virani SS, Wilson PWF, Elassal J, Lee LV, Wang TY, Peterson ED. Association of patient perceptions of cardiovascular risk and beliefs on statin drugs with racial differences in statin use: insights from the Patient and Provider Assessment of Lipid Management Registry. JAMA Cardiol 2018 [Epub ahead of print].

96. Wang Y, Jia L, Hu Z, Entman ML, Mitch WE, Wang Y. AMP-activated protein kinase/myocardin-related transcription factor-A signaling regulates fibroblast activation and renal fibrosis. Kidney Int 2018;93,81–94

97. Rebholz CM, Selvin E, Liang M, Ballantyne CM, Hoogeveen RC, Aguilar D, McEvoy JW, Grams ME, Coresh J. Plasma galectin-3 levels are associated with the risk of incident chronic kidney disease. Kidney Int 2018;93:252–259.

98. Ridker PM, MacFadyen JG, Thuren T, Everett BM, Libby P, Glynn RJ, on behalf of the; CANTOS Trial Group [Collaborators (113): Ridker P, Lorenzatti A, Krum H, ..., Ballantyne C, ...]. Effect of interleukin-1β inhibition with canakinumab on incident lung cancer in patients with atherosclerosis: exploratory results from a randomised, double-blind, placebo-controlled trial. Lancet 2017;390:1833–1842.

99. Ridker PM, MacFadyen JG, Everett BM, Libby P, Thuren T, Glynn RJ, on behalf of the CANTOS Trial Group [Collaborators (56): Ridker PM, MacFadyen JG, Everett BM, ..., Ballantyne C, ...]. Relationship of C-reactive protein reduction to cardiovascular event reduction following treatment with canakinumab: a secondary analysis from the CANTOS randomised controlled trial. Lancet 2018;391:319–328.

100. Zewinger S, Kleber ME, Tragante V, McCubrey RO, Schmidt AF, Direk K, Laufs U, Werner C, Koenig W, Rothenbacher D, Mons U, Breitling LP, Brenner H, Jennings RT, Petrakis I, Triem S, Klug M, Filips A, Blankenberg S, Waldeyer C, Sinning C, Schnabel RB, Lackner KJ, Vlachopoulou E, Nygård O, Svingen GFT, Pedersen ER, Tell GS, Sinisalo J, Nieminen MS, Laaksonen R, Trompet S, Smit RAJ, Sattar N, Jukema JW, Groesdonk HV, Delgado G, Stojakovic T, Pilbrow AP, Cameron VA, Richards AM, Doughty RN, Gong Y, Cooper-DeHoff R, Johnson J, Scholz M, Beutner F, Thiery J,

Smith JG, Vilmundarson RO, McPherson R, Stewart AFR, Cresci S, Lenzini PA, Spertus JA, Olivieri O, Girelli D, Martinelli NI, Leiherer A, Saely CH, Drexel H, Mündlein A, Braund PS, Nelson CP, Samani NJ, Kofink D, Hoefer IE, Pasterkamp G, Quyyumi AA, Ko YA, Hartiala JA, Allayee H, Tang WHW, Hazen SL, Eriksson N, Held C, Hagström E, Wallentin L, Åkerblom A, Siegbahn A, Karp I, Labos C, Pilote L, Engert JC, Brophy JM, Thanassoulis G, Bogaty P, Szczeklik W, Kaczor M, Sanak M, Virani SS, Ballantyne CM, Lee VV, Boerwinkle E, Holmes MV, Horne BD, Hingorani A, Asselbergs FW, Patel RS, on behalf of the GENIUS-CHD consortium, Krämer BK, Scharnagl H, Fliser D, März W, Speer T. Relations between lipoprotein(a) concentrations, LPA genetic variants, and the risk of mortality in patients with established coronary heart disease: a molecular and genetic association study. Lancet Diabetes Endocrinol 2017;5:534–543.

101. Saeed A, Kampangkaew J, Nambi V. Prevention of cardiovascular disease in women. Methodist Debakey Cardiovasc J 2017;13:185–192.

102. Giugliano RP, Mach F, Zavitz K, Kurtz C, Im K, Kanevsky E, Schneider J, Wang H, Keech A, Pedersen TR, Sabatine MS, Sever PS, Robinson JG, Honarpour N, Wasserman SM, Ott BR, for the EBBINGHAUS Investigators [Collaborators (461): Wittert G, Begg A, Simpson R, ... Ballantyne C, ...]. Cognitive function in a randomized trial of evolocumab. N Engl J Med 2017;377:633–643.

103. Ridker PM, Everett BM, Thuren T, MacFadyen JG, Chang WH, Ballantyne C, Fonseca F, Nicolau J, Koenig W, Anker SD, Kastelein JJP, Cornel JH, Pais P, Pella D, Genest J, Cifkova R, Lorenzatti A, Forster T, Kobalava Z, Vida-Simiti L, Flather M, Shimokawa H, Ogawa H, Dellborg M, Rossi PRF, Troquay RPT, Libby P, Glynn RJ, for the CANTOS Trial Group. Antiinflammatory therapy with canakinumab for atherosclerotic disease. N Engl J Med 2017;377:1119–1131.

104. HPS3/TIMI55–REVEAL Collaborative Group [Bowman L, Hopewell JC, Chen F, Wallendszus K, Stevens W, Collins R, Wiviott SD, Cannon CP, Braunwald E, Sammons E, Landray MJ; Collaborators (2325): Jiang L, Armitage J, Haynes R, ..., Ballantyne C, ...]. Effects of anacetrapib in patients with atherosclerotic vascular disease. N Engl J Med 2017;377:1217–1227.

105. Liu DJ, Peloso GM, Yu H, Butterworth AS, Wang X, Mahajan A, Saleheen D, Emdin C, Alam D, Alves AC, Amouyel P, Di Angelantonio E, Arveiler D, Assimes TL, Auer PL, Baber U, Ballantyne CM, Bang LE, Benn M, Bis JC, Boehnke M, Boerwinkle E, Bork-Jensen J, Bottinger EP, Brandslund I, Brown M, Busonero F, Caulfield MJ, Chambers JC, Chasman DI, Chen YE, Chen YI, Chowdhury R, Christensen C, Chu AY, Connell JM, Cucca F, Cupples LA, Damrauer SM, Davies G, Deary IJ, Dedoussis G, Denny JC, Dominiczak A, Dubé MP, Ebeling T, Eiriksdottir G, Esko T, Farmaki AE, Feitosa MF, Ferrario M, Ferrieres J, Ford I, Fornage M, Franks PW, Frayling TM, Frikke-Schmidt R, Fritsche LG, Frossard P, Fuster V, Ganesh SK, Gao W, Garcia ME, Gieger C, Giulianini F, Goodarzi MO, Grallert H, Grarup N, Groop L, Grove ML, Gudnason V, Hansen T, Harris TB, Hayward C, Hirschhorn JN, Holmen OL, Huffman J, Huo Y, Hveem K, Jabeen S, Jackson AU, Jakobsdottir J, Jarvelin MR, Jensen GB, Jørgensen ME, Jukema JW, Justesen JM, Kamstrup PR, Kanoni S, Karpe F, Kee F, Khera AV, Klarin D, Koistinen HA, Kooner JS, Kooperberg C, Kuulasmaa K, Kuusisto J, Laakso M, Lakka T, Langenberg C, Langsted A, Launer LJ, Lauritzen T, Liewald DCM, Lin LA, Linneberg A, Loos RJF, Lu Y, Lu X, Mägi R, Malarstig A, Manichaikul A, Manning AK, Mäntyselkä P, Marouli E, Masca NGD, Maschio A, Meigs JB, Melander O, Metspalu A, Morris AP, Morrison AC, Mulas A, Müller-Nurasyid M, Munroe PB, Neville MJ, Nielsen JB, Nielsen SF, Nordestgaard BG, Ordovas JM, Mehran R, O'Donnell CJ, Orho-Melander M, Molony CM, Muntendam P, Padmanabhan S, Palmer CNA, Pasko D, Patel AP, Pedersen O, Perola M, Peters A, Pisinger C, Pistis G, Polasek O, Poulter N, Psaty BM, Rader DJ, Rasheed A, Rauramaa R, Reilly DF, Reiner AP, Renström F, Rich SS, Ridker PM, Rioux

JD, Robertson NR, Roden DM, Rotter JI, Rudan I, Salomaa V, Samani NJ, Sanna S, Sattar N, Schmidt EM, Scott RA, Sever P, Sevilla RS, Shaffer CM, Sim X, Sivapalaratnam S, Small KS, Smith AV, Smith BH, Somayajula S, Southam L, Spector TD, Speliotes EK, Starr JM, Stirrups KE, Stitziel N, Strauch K, Stringham HM, Surendran P, Tada H, Tall AR, Tang H, Tardif JC, Taylor KD, Trompet S, Tsao PS, Tuomilehto J, Tybjaerg-Hansen A, van Zuydam NR, Varbo A, Varga TV, Virtamo J, Waldenberger M, Wang N, Wareham NJ, Warren HR, Weeke PE, Weinstock J, Wessel J, Wilson JG, Wilson PWF, Xu M, Yaghootkar H, Young R, Zeggini E, Zhang H, Zheng NS, Zhang W, Zhang Y, Zhou W, Zhou Y, Zoledziewska M; CHARGE Diabetes Working Group; EPIC-InterAct Consortium; EPIC-CVD Consortium; GOLD Consortium; VA Million Veteran Program, Howson JMM, Danesh J, McCarthy MI, Cowan CA, Abecasis G, Deloukas P, Musunuru K, Willer CJ, Kathiresan S. Exome-wide association study of plasma lipids in >300,000 individuals. Nat Genet 2017;49:1758–1766.

106. Li N, Dobrev D. Targeting atrial fibrillation promoting atrial structural remodeling: is this a viable strategy in patients with heart failure? Naunyn Schmiedebergs Arch Pharmacol 2018;391:231–233.

107. Walker KA, Hoogeveen RC, Folsom AR, Ballantyne CM, Knopman DS, Windham BG, Jack CR Jr, Gottesman RF. Midlife systemic inflammatory markers are associated with late-life brain volume: the ARIC study. Neurology 2017;89:2262–2270.

108. Virani SS, Akeroyd JM, Ramsey DJ, Deswal A, Nasir K, Rajan SS, Ballantyne CM, Petersen LA. Health care resource utilization for outpatient cardiovascular disease and diabetes care delivery among advanced practice providers and physician providers in primary care. Popul Health Manag 2018;21:209–216.

109. Wu J, Wu H, An J, Ballantyne CM, Cyster JG. Critical role of integrin CD11c in splenic dendritic cell capture of missing-self CD47 cells to induce adaptive immunity. Proc Natl Acad Sci U S A 2018;115:6786–6791.

110. Fashanu OE, Heckbert SR, Aguilar D, Jensen PN, Ballantyne CM, Basu S, Hoogeveen RC, deFilippi C, Cushman M, Folsom AR. Galectin-3 and venous thromboembolism incidence: the Atherosclerosis Risk in Communities (ARIC) Study. Res Pract Thromb Haemost 2017;1:223–230.

111. Walker KA, Power MC, Hoogeveen RC, Folsom AR, Ballantyne CM, Knopman DS, Windham BG, Selvin E, Jack CR Jr, Gottesman RF. Midlife systemic inflammation, late-life white matter integrity, and cerebral small vessel disease: the Atherosclerosis Risk in Communities Study. Stroke 2017;48:3196–3202.

112. Faza NN, Virani SS, Nambi V, Shah T. Aberrant course of pacemaker leads: when left is left. Tex Heart Inst J 2018;45:52–53.

113. McBride CL, Akeroyd JM, Ramsey DJ, Nambi V, Nasir K, Michos ED, Bush RL, Jneid H, Morris PB, Bittner VA, Ballantyne CM, Petersen LA, Virani SS. Statin prescription rates and their facility-level variation in patients with peripheral artery disease and ischemic cerebrovascular disease: Insights from the Department of Veterans Affairs. Vasc Med 2018;23:232–240.

B. Awards and honors 1. Ballantyne: Houston Chronicle Top Doctors 2017 2. Ballantyne: Castle Connaly Top Doctors: Southeast Texas, Castle Connaly Medical

Ltd., 2017 3. Ballantyne: Castle Connaly Top Doctors in Texas for the Speciality of Cardiovascular

Disease, Castle Connolly Medical Ltd., 2017 4. Ballantyne: Castle Connaly Top Doctors in America, Castle Connolly Medical Ltd., 2018

5. Ballantyne: Selected by his peers for inclusion in Best Doctors in America®, Best Doctors, Inc., Aiken, South Carolina, 2018

6. Ballantyne: 2017 Highly Cited Researcher presented by Clarivate Analytics, Web of Science, top 1% of researchers most cited

7. Entman: International Academy of Cardiovascular Sciences Lifetime Achievement Award in Cardiovascular Science, Medicine and Surgery, August 2017

8. Li: University of Houston Teaching Excellence Award for Group Teaching, 2017–2018 9. Virani: Norton Rose Fulbright Faculty Excellence Award, Development of Enduring

Educational Materials, Baylor College of Medicine 10. Virani: Inducted into Best Doctors database C. Professional organization/association offices held 1. Ballantyne: Chair, LDL: Address the Risk Think Tank, American College of Cardiology 2. Ballantyne: Writing Committee, Expert Consensus Decision Pathway on the Role of

Non-Statin Therapies for LDL-Cholesterol Lowering in the Management of Atherosclerotic Cardiovascular Disease Risk, American College of Cardiology

3. Ballantyne: Board, American Society for Preventive Cardiology 4. Ballantyne: Board, National Lipid Association 5. Ballantyne: Scientific Meeting Committee, National Lipid Association 6. Ballantyne: Co-chair, Project Review Committee, National Lipid Association 7. Brunner: Member, Grant Peer Review Committee, Innovative Project Award (IPA)

Committee, American Heart Association 8. Jones: Chief Science Officer, National Lipid Association 9. Virani: Chair, Leadership Council and Council for the Prevention of Cardiovascular

Disease, American College of Cardiology 10. Virani: Chair, Research and Publications Committee, PINNACLE Registry, National

Cardiovascular Data Registry, American College of Cardiology 11. Virani: Member, LDL: Address the Risk Think Tank, American College of Cardiology 12. Virani: Member, Guideline Tool Work Group, 2018 ACC/AHA Cholesterol Guideline,

American College of Cardiology 13. Virani: Member, Research to Practice (R2P) Initiative Work Group, National

Cardiovascular Data Registry, American College of Cardiology 14. Virani: Topic Coordinator (Prevention), Annual Scientific Session Program Committee,

American College of Cardiology 15. Virani: Chair, Heart Disease and Stroke Statistics Committee, American Heart

Association 16. Virani: Member, EPI Leadership Committee, Council on Epidemiology and Prevention,

American Heart Association 17. Virani: Board of Directors, American Society of Preventive Cardiology 18. Wu: Member, Grant Peer Review Committee, Lipids BSc 2 Committee, American Heart

Association D. Editorial board memberships and editorial positions 1. Ballantyne: Editorial Director, lipidsonline.org 2. Ballantyne: Editorial Board, Circulation 3. Ballantyne: Editorial Board, Clinical and Translational Science 4. Ballantyne: Editorial Board, Current Cardiology Reviews

5. Ballantyne: Editorial Board, Future Lipidology 6. Cruz: Editorial Board, Thrombosis & Haemostasis: Research 7. Foreyt: Editorial Board, American Journal of Health Behavior 8. Foreyt: Editorial Board, American Journal of Health Promotion 9. Foreyt: Editorial Board, American Journal of Lifestyle Medicine 10. Foreyt: Editorial Board, Childhood Obesity 11. Foreyt: Editorial Board, Nutrition Today 12. Foreyt: Editorial Board, Obesity and Weight Management 13. Foreyt: Editorial Board, Obesity Research and Clinical Practice 14. Jones: Associate Editor, Journal of Clinical Lipidology 15. Pi: Guest Editor, Oxidative Medicine and Cellular Longevity 16. Pi: Review Editor, Arteriosclerosis, Thrombosis and Vascular Biology 17. Pi: Review Editor, Frontiers 18. Pi: Review Editor, Journal of Molecular and Cellular Cardiology 19. Pi: Review Editor, Nature Communications 20. Virani: Associate Editor, Innovations, ACC.org 21. Virani: Editorial Team Member and Chair for Digital Strategy, Cardiovascular Prevention

Section, ACC.org (educational web portal for the American College of Cardiology)

22. Virani: Advisory Board, Advances in Therapy 23. Virani: Guest Editor, Circulation 24. Virani: Editorial Board, Circulation 25. Virani: Section Editor, "Coronary Heart Disease," Current Atherosclerosis Reports 26. Virani: Associate Editor, Journal of Clinical Lipidology (Section specialty: Cardiovascular

Outcomes and Guidelines) 27. Virani: Associate Editor, Global Heart (Official Journal of the World Heart Federation) 28. Wu: Guest Associate Editor, Frontiers in Immunology (T cell biology in adipose tissue) 29. Wu: Editorial Board, Archives of Inflammation 30. Wu: Editorial Board, International Journal of Hematology Research 31. Wu: Editorial Board, Journal of Pediatric Endocrinology 32. Wu: Editorial Board, JSM Atherosclerosis 33. Wu: Editorial Board, SM Journal of Endocrinology and Metabolism E. Other significant accomplishments 1. Brunner: Reviewer, Biomedical Imaging Technology Study Section–A, Center for

Scientific Review, NIH, Bethesda, MD 2. Brunner: Reviewer and "Application Chair," ZRG1 MOSS-D (82) A NIH study Section

(Musculoskeletal, Oral, Skin, Rheumatology and Rehab Sciences [R15]) 3. Brunner: Invited Keynote Speaker, "Skeletal Calf Muscle Perfusion Measurement To

Assess Peripheral Arterial Disease," 10th European Symposium Of Vascular Biomaterials Strasbourg, France

4. Brunner: Invited Guest Speaker, Special Seminar on Magnetic Resonance Imaging in Peripheral Artery Disease, Penn State Heart and Vascular Institute, Penn State Health Milton S. Hershey Medical Center, Hershey, PA

5. Brunner: Invited Speaker, "Inflammation, Microvascular Perfusion, and Peripheral Arterial Disease," George and Angelina Kostas Research Center for Cardiovascular Nanomedicine, Annual International Meeting, Houston, TX

6. Brunner: Invited Presenter, "Inflammation, Microvascular Perfusion and Peripheral Arterial Disease," American Heart Association Reverse Site Visit as one of the 9

finalists the Clinical Project of the Strategically Focused Vascular Disease Research Network (Center Director: John P. Cooke), Dallas, TX

7. Brunner: Invited Presenter, "Advanced Physics, Fourier Transformation Parallel Imaging, and MRI Safety," Houston Methodist Cardiovascular Magnetic Resonance Workshop, DeBakey Institute for Cardiovascular Education & Training, Houston Methodist Hospital, Houston, TX

8. Brunner: Didactic Lectures, Cardiovascular sciences graduate course (GS-CS-411)—Cardiovascular Physiology, and Structural Basis of Human Diseases (GS-SB-423), BCM

9. Brunner: Poster Judge, 3rd Annual VA Research Poster Session. Michael E. DeBakey VA Medical Center, Houston, TX

10. Cruz: Invited lecture, "A Novel Target to Prevent Microvascular Thrombosis and Multiple Organ Dysfunction Syndrome in Sepsis," Microbiology & Immunology, UTMB

11. Cruz: Invited lecture, "Novel Targets to Prevent Microvascular Thrombosis in Sepsis," CVRI seminar series, BCM

12. Li: Ad hoc reviewer, 2018 NIH ESTA Study Section 13. Li: Ad hoc reviewer, 2017 Farouk Jabre Research Proposal 14. Li: Invited lecture, "The inflammasome in AF," Heart Failure Association Winter Meeting

on Translational Heart Failure Research 2018, Les Diablerets, Switzerland 15. Li: Invited lecture, "Emerging role of the inflammasome as novel target in atrial fibrillation

therapy," American Heart Association Scientific Session 2017, Anaheim, CA 16. Li: Invited lecture, "Role of Cardiac Inflammasome in the Pathogenesis of Atrial

Fibrillation," IMBS 2018 Research Conference and Retreat, BCM 17. Li: Invited lecture, "Emerging Role of Cardiac Inflammasome In the Development of

Atrial Fibrillation," CVRI seminar series, BCM 18. Li: Invited conference moderator, Ion Channels and Arrhythmias session, American

Heart Association Basic Cardiovascular Sciences (BCVS) Council Scientific Sessions 2017, Portland, OR

19. Pi: Invited lecture, "A secret life of the vascular endothelium," Society of Chinese Bioscientists in America–Texas Chapter annual symposium

20. Pi: Invited lecture, "The role of vascular endothelium in metabolic health," Texas Heart Institute seminar series

21. Pi: Course organizer, TBMM graduate program Bench to Bedside Series, Term 3: Current topics in translational cardiovascular medicine

22. Pi: Seminar host, TBMM graduate program Bench to Bedside Series. "Ahoy CRISPR" presented by Dr. Joseph M. Miano, University of Rochester

23. Pi: Poster judge, CVRI 2018 Symposium, BCM 24. Pi: Grant proposal reviewer, CVRI Pilot Awards, BCM 25. Pi: Reviewer of graduate student candidates, Molecular Physiology & Biophysics

Graduate Program, BCM 26. Pi: Member of Graduate student committee for Nirva Mumcuyan, Developmental Biology

Program, BCM 27. Virani: Invited speaker, Global Cardiovascular Disease Prevention webinars in

Indonesia, Malaysia, Vietnam, and UAE 28. Wu: Member, NIH/NIGMS SCORE Grant Review Panel 29. Wu: Member, American Heart Association Grant Peer Review Committee, Lipids BSc

Committee 30. Wu: Member, Immunology Graduate Program Qualifying Exam Committee, BCM 31. Wu: Member, Immunology Graduate Admission Committee, BCM 32. Wu: English language interviewer, J1 visa candidates, BCM 33. Wu: Poster judge, CVRI 2018 Symposium, BCM

34. Wu: Didactic Lecture, Cardiovascular Disease and Pathology (GS-CS-412), BCM 35. Wu: Judge, Young Investigator Award Oral Presentation, 2018 CAAC-MPVD-ATVB

Symposium, San Francisco, CA F. Grants 1. Ballantyne (co-PI): Profiling Cardiovascular Events and Biomarkers in the Very Old to

Improve Personalized Approaches for the Prevention of Cardiac and Vascular Disease; NIH/NHLBI (R01); annual direct costs $549,802 (09/01/2016–08/31/2020)

2. Ballantyne (coinvestigator): Atherosclerosis Risk in Communities (ARIC) Study–Field Centers; NIH; annual direct costs $311,673 (11/15/2016–11/14/2021)

3. Ballantyne (coinvestigator): Monocyte Activation and the Role of CD11c in Obesity-Linked Metabolic Syndrome; NIH/NHLBI (R01); annual direct costs $241,769 (04/01/2015–03/31/2020)

4. Ballantyne (coinvestigator): Diabetes and Prediabetes in Older Adults; NIH/NIDDK (R01); annual direct costs $36,371 (01/01/2016–12/31/2020)

5. Ballantyne (coinvestigator): miRNAs, Whole Diet, and Coronary Heart Disease; NIH/NHLBI (R56); total direct costs $12,147 (09/01/2016–08/31/2018)

6. Ballantyne (coinvestigator): Comparative Effectiveness of Physicians versus Non-physicians for the Delivery of Outpatient Diabetes Care: Implications for Access to Care under the Affordable Care Act; American Diabetes Association; total direct costs: $486,957 (01/01/2014–12/31/2017)

7. Ballantyne (PI): The Familial Hypercholesterolemia Foundation Cascade-FH Registry; Duke University; total direct costs $20,000 (07/01/2014–06/30/2019)

8. Ballantyne (PI): Measurement of Galectin-3 at Visit 4 and Visit 5 for the Full ARIC Cohort; Abbott Laboratories; total direct costs $31,500 (03/14/2014–07/31/2018)

9. Ballantyne (PI): hsTroponin Screening at Visit 4 and Visit 5 for the Full ARIC Cohort; Abbott Laboratories; total direct costs $371,965 (05/12/2014–05/11/2019)

10. Ballantyne (PI): A Randomized, Double-blind, Placebo-controlled, Dose-ranging Phase 2 Study of ISIS 681257 Administered Subcutaneously to Patients with Hyperlipoproteinemia(a) and Established Cardiovascular Disease (CVD); Akcea Therapeutics; total direct costs $172,510 (02/28/2017–02/27/2020)

11. Ballantyne (PI): A Randomized, Double-blind, Placebo-controlled, Dose-ranging Phase 2 Study of ISIS 678354 Administered Subcutaneously to Patients with Hypertriglyceridemia and Established Cardiovascular Disease; Akcea Therapeutics; total direct costs $206,886 (03/08/2018–03/07/2021)

12. Ballantyne (PI): A Multicenter, Controlled, Open-Label Extension (OLE) Study to Assess the Long-Term Safety and Efficacy of AMG-145; Amgen, Inc; total direct costs $43,965 (06/01/2013–02/08/2018)

13. Ballantyne (PI): GAUSS-3A—Double-Blind, Randomized, Multicenter Study to Evaluate the Safety and Efficacy of AMG 145, Compared with Ezetimibe, in Hypercholesterolemic Subjects Unable to Tolerate an Effective Dose of an HMG-CoA Reductase Inhibitor due to Muscle Related Side Effects; Amgen, Inc; total direct costs $60,085 (02/18/2014–03/21/2018)

14. Ballantyne (PI): A Multicenter, Open-Label, Single-Arm, Extension Study to Assess Long-Term Safety of Evolocumab Therapy in Patients with Clinically Evident Cardiovascular Disease; Amgen Inc; total direct costs $45,670 (08/17/2016–12/31/2021)

15. Ballantyne (PI): A Randomized, Double-Blind, Placebo-Controlled, Multicenter Long-

Term Safety and Tolerability Study of ETC 1002 in Patients with Hyperlipidemia at High Cardiovascular Risk Who Are Not Adequately Controlled by Their Lipid-Modifying Therapy; Esperion Therapeutics; total direct costs $62,963 (06/27/2016–06/29/2018)

16. Ballantyne (PI): A Randomized, Double-Blind, Placebo-Controlled Study to Assess the Effects of Bempedoic Acid (ETC-1002) on the Occurrence of Major Cardiovascular Events in Patients with, or at High Risk for, Cardiovascular Disease Who Are Statin Intolerant; Esperion Therapeutics; total direct costs $40,614 (05/17/2017–04/30/2020)

17. Ballantyne (PI): A randomized, double-blind, placebo-controlled, parallel group, multicenter study to evaluate the efficacy and safety of bempedoic acid (ETC1002) 180 mg/day as add-on to ezetimibe therapy in patients with elevated LDL-C; Esperion Therapeutics; total direct costs $29,253 (06/07/2017–04/25/2018)

18. Ballantyne (PI): A Randomized, Double-Blind, Parallel-group Study to Evaluate the Efficacy and Safety of Bempedoic Acid 180 mg + Ezetimibe 10 mg Fixed-dose Combination Combination Compared to Bempedoic Acid, Ezetimibe, and Placebo Alone in Patients Treated With Maximally Tolerated Statin Therapy; Esperion Therapeutics; total direct costs $21,194 (11/29/2017–11/17/2018)

19. Ballantyne (PI): A Multicenter Open-Label Extension (OLE) Study to Assess the Long-term Safety and Efficacy of Bempedoic Acid (ETC-1002) 180 mg; Esperion Therapeutics; total direct costs $22,400 (08/07/2017–12/31/2019)

20. Ballantyne (PI): A Randomized, Double-Blind, Placebo-Controlled, Event-Driven Trial of Quarterly Subcutaneous Canakinumab in the Prevention of Recurrent Cardiovascular Events among Stable Post-Myocardial Infarction Patients with Elevated hsCRP; Novartis Pharmaceutical Company; total direct costs $125,877 (04/25/2011–12/31/2020)

21. Brunner (PI): Microvascular Perfusion Assessment of Ischemic Diabetic Ulcers Using MRI; NIH/NHLBI (K25); annual direct costs $154,958 (12/01/2014–12/31/2019)

22. Brunner (PI): MRI Based Calf Muscle Perfusion to Assess Patients with Symptomatic PAD; NIH/NHLBI (R01); annual direct costs $350,417 (08/01/2017–07/31/2022)

23. Brunner (coinvestigator): Biomarker Guided Therapies in Stage A/B Heart Failure; VA Office of Research and Development; annual direct costs $14,189 (04/01/2014–03/31/2019)

24. Cieslik (co-PI): Trafficking Leukocytes in the Aging Mouse Heart: in Vivo MRI and Flow Cytometry; BCM Cardiovascular Research Institute Pilot Award (09/01/2017–06/30/2018)

25. Cieslik (coinvestigator): Role of Blood-Borne Fibroblast Precursors in Ischemic Cardiomyopathy; NIH/NHLBI (R01); annual direct costs $250,000 (07/01/2007–11/30/2017)

26. Cieslik (PI): A Spontaneous Mutation in Nnt Gene Promotes Cardiac Fibrosis in the Aging Heart; The Medallion Foundation; total direct costs $50,000 (07/01/2015–12/31/2018)

27. Cruz (multi-PI): Microvascular Thrombosis in Systemic Inflammation; NIH/NIGMS (R01); annual direct costs $220,000 (09/25/2014–05/31/2019)

28. Cruz (co-PI): Role of Vimentin in Thrombosis and Stroke; NIH/NINDS (R01); annual direct costs $381,958 (09/01/2016–05/31/2021)

29. Entman (PI): Role of Blood-Borne Fibroblast Precursors in Ischemic Cardiomyopathy; NIH/NHLBI (R01); annual direct costs $250,000 (07/01/2007–11/30/2017)

30. Entman (PI): Researching the Aging Heart; The Curtis and Doris K. Hankamer Foundation; annual direct costs $40,000 (01/01/2001–12/31/2018)

31. Foreyt (PI): Study of Health Outcomes of Weight-Loss (Look AHEAD) Trial; NIH/NIDDK (U01); annual direct costs $152,265 (09/01/1999–01/31/2019)

32. Foreyt (PI): Vitamin D to Prevent Type 2 Diabetes (D2d Study); NIH/NIDDK (U01); annual direct costs $45,309 (06/01/2013–01/31/2019)

33. Hoogeveen (coinvestigator): Atherosclerosis Risk in Communities (ARIC) Study—Field Centers; NIH/NHLBI; annual direct costs $311,673 (11/15/2016–11/14/2021)

34. Hoogeveen (coinvestigator): Diabetes and Pre-diabetes in Older Adults; NIH/NIDDK (R01); total direct costs $200,000 (09/01/2016–12/31/2020)

35. Hoogeveen (coinvestigator): Endogenous Hormones and Postmenopausal Breast Cancer: Etiologic Insights and Improving Risk Prediction; NIH/NCI; annual direct costs $76,772 (06/15/2017–03/31/2022)

36. Hoogeveen (PI): Relation of Lipoprotein(a) and Small Dense LDL-C (sdLDL-C) to Incident CHD and Stroke: the ARIC Study; Denka Seiken Co, Ltd; annual direct costs $18,021 (10/01/2010–12/31/2017)

37. Hoogeveen (PI): Relationship of Small-Dense LDL Cholesterol (sdLDL-C) and Lp(a) with Progression of Atherosclerosis in the Study of Coronary Atheroma by Intravascular Ultrasound: Effect of Rosuvastatin versus Atorvastatin (SATURN) Trial; Denka Seiken Co, Ltd (11/01/2013–12/31/2017)

38. Hoogeveen (PI): Lipoprotein Subfractions Study: the ARIC Study; Denka Seiken Co, Ltd; annual direct costs $56,750 (11/01/2015–08/31/2018)

39. Jones: A Multi-center, Prospective, Randomized, Double-Blind, Placebo-Controlled , Parallel-Group Study to Evaluate the Effect of AMR101 on Cardiovascular Health and Mortality in Hpertriglyceridemic Patients with Cardiovascular Disease or at High Risk for Cardiovascular Disease: REDUCE-IT (Reduction of Cardiovascular Events with EPA Intervention Trial); Amarin Pharmaceuticals; total direct costs $25,000 (06/01/2012–12/31/2018)

40. Li (PI): Inflammasome Mediated Pathogenesis of Atrial Fibrillation; NIH/NHLBI (R56); annual direct costs $250,000 (09/01/2016–08/31/2018)

41. Li (PI): The Role of Inflammasome in the Pathogenesis of Atrial Fibrillation; NIH/NHLBI (R01); annual direct costs $379,069 (09/01/2017–06/30/2021)

42. Li (PI): Transcriptional Regulation of Ryanodine Receptor 2 in Atrial Fibrillation; American Heart Association Scientist Development Grant; annual direct costs $379,069 (09/01/2017–06/30/2021)

43. Li (coinvestigator): Novel Roles of FE2+, 2-Oxoglutarate-Dependent Dioxygenases in Cardiac Function; NIH/NHLBI (R01); annual direct costs $250,000 (09/01/2015–08/31/2020)

44. Li (coinvestigator): Pitx2 in Atrial Fibrillation; NIH/NHLBI (R01); annual direct costs $327,304 (02/01/2018–02/28/2023)

45. Nambi (PI): Biomarker Guided Therapies in Stage A/B Heart Failure; VA Office of Research and Development; annual direct costs $14,189 (04/01/2014–03/31/2019)

46. Nambi (PI): TIMI 55/REVEAL (Randomized Evaluation of the Effects of Anacetrapib through Lipid-Modification): A Large Scale, Randomized, Placebo-Controlled Trial of the Clinical Effects of Anacetrapib among People with Established Vascular Disease; Brigham and Women's Hospital; total direct costs $150,000 (11/01/2011–02/28/2019)

47. Pi (PI): LRP1 and Endothelial Function; NIH/NHLBI (R01); annual direct costs $250,000 (08/01/2013–05/31/2019)

48. Pi (PI): Signaling in Endothelial Growth and Angiogenesis; NIH/NHLBl (R01); annual direct costs $250,000 (12/18/2013–12/31/2018)

49. Trial (coinvestigator): Role of Blood-Borne Fibroblast Precursors in Ischemic Cardiomyopathy; NIH/NHLBI (R01); annual direct costs $250,000 (07/01/2007–11/30/2017)

50. Vijayan (PI): Serine/Threonine Phosphatases and Platelet Physiology; NIH/NHLBI (R01); annual direct costs $250,000 (03/01/2013–02/28/2019)

51. Vijayan (multi-PI): Microvascular Thrombosis in Systemic Inflammation; NIH/NIGMS (R01); annual direct costs $220,000 (09/25/2014–05/31/2019)

52. Vijayan (PI of subcontract to Baylor College of Medicine): Aspirin-PC for Chemoprevention of Colorectal Cancer; NIH/NCI (R42); annual direct costs $86,000 (05/01/2017–04/30/2019)

53. Vijayan (PI): PP2B Modulates RhoA Activation and Platelet Function by Targeting RhoGDI; American Heart Association; annual direct costs $70,000 (07/01/2017–06/30/2019)

54. Virani (PI): Comparative Effectiveness of Physicians versus Non-physicians for the Delivery of Outpatient Diabetes Care: Implications for Access to Care under the Affordable Care Act; American Diabetes Association; total direct costs: $486,957 (01/01/2014–12/31/2017)

55. Virani (PI): Determining and Targeting Reasons for Low Statin U se to Improve Guideline-Concordant Satatin Therapy in High-Risk Patients; VA Merit Award; total direct costs: $1,097,703 (07/01/2017–06/30/2021)

56. Wu (PI): Monocyte Activation and the Role of CD11c in Obesity-Linked Metabolic Syndrome; NIH/NHLBI (R01); annual direct costs $241,769 (04/01/2015–03/31/2020)

57. Wu (PI): ApoCIII, Triglyceride-Rich Lipoproteins and Atherogenesis; American Heart Association; total direct costs $140,000 (07/01/2016–06/30/2019)

58. Wu (PI): Macrophage/Dendritic Cell Activation and Inflammation in Diet-Induced Obesity; American Diabetes Association; annual direct costs $104,546 (01/01/2017–12/31/2019)

59. Wu (co-PI): Imaging Monocyte Tracking into Atherosclerosis and Adipose Tissue in Mice; BCM Cardiovascular Research Institute Pilot Award; total direct costs $15,000 (09/01/2017–06/30/2018)

60. Xie (PI): Novel Roles of FE2+, 2-Oxoglutarate-Dependent Dioxygenases in Cardiac Function; NIH/NHLBI (R01); annual direct costs $250,000 (09/01/2015–08/31/2020)

61. Xie (coinvestigator): LRP1 and Endothelial Function; NIH/NHLBI (R01); annual direct costs $250,000 (08/01/2013–05/31/2019)

62. Xie (coinvestigator): Signaling in Endothelial Growth and Angiogenesis; NIH/NHLBl (R01); annual direct costs $250,000 (12/18/2013–12/31/2018)

Endocrinology, Diabetes, and Metabolism


August 29, 2018 Dear Colleagues, Together with the entire faculty of the Endocrinology, Diabetes & Metabolism Section, I would like to welcome everybody to our 2018 Annual Report. 2018 has been an eventful year for us, with new unique contributions in research, scholarship, clinical care and education. The section has published more than 50 papers, many of them in top journals, and has been the recipient of an unprecedented six NIH R01 grants. We have been active in national and international meetings and organizations and offer daily medical care to the Houston community at the Baylor St. Luke’s Medical Center, the Michael E. DeBakey VA Medical Center, Ben Taub General Hospital, Smith Clinic and the St. Thomas Street Clinic. Our trans-institutional fellowship program with MD Anderson Cancer Center and Texas Children Hospital graduates five outstanding new endocrine fellows every year. As we are about to enter the third decade of the XXI century, our faculty is 100% committed to advance the science and clinical practice of endocrinology, diabetes & metabolism to the next level. Please enjoy and thank you for your interest.

Marco Marcelli M.D. Ad interim chief Section of Endocrinology, Diabetes & Metabolism

of 18

Section of Endocrinology, Diabetes and Metabolism Department of Medicine, Baylor College of Medicine (1 July 2017–30 June 2018) Faculty Agarwal, Neeti Ph.D. Bajaj, Mandeep M.D. Balasubramanyam, Ashok M.D. Boparai, Jasmine M.D. Chen, Rui M.D. Dufrane, Nancy Greta Renee Gaba, Ruchi M.D. Garber, Alan J M.D., Ph.D. Ha, Ngueyn M.D. Hartig, Sean Ph.D. Jiang, Bryan M.D. Marcelli, Marco M.D.

McKay, Siripoom M.D. Mediwala, Sanjay N M.D. Mehta, Munira O.D. Pietropaolo, Massimo M.D. Ram, Nalini M.D. Samson, Susan Leanne M.D. Sekhar, Rajagopal Viswanath M.D. Sun, Zheng Ph.D. Vasudevan, Madhuri M.D., M.P.H. Villareal, Dennis M.D. Villareal, Reina M.D. Zhang, Li Ph.D.

Contents

A. Publications………………………………………………..……………..…….. 3 B. Awards and Honors………………………………………..………………….. 8 C. Books and Book Chapters………………………………………………….... 9 D. Professional Organization/Association Offices Held……………………. 10 E. Editorial Board Memberships and Editorial Positions……………………. 12 F. Grants……………………………………………………………………………. 13

of 18

A. Publications

1. Acevedo-Calado M, James EA, Morran MP, Pietropaolo SL, Ouyang Q, Arribas-Layton D, Songini M, Liguori M, Casu A, Auchus RJ, Huang S, Yu L, Michels A, Gianani R, Pietropaolo M. Identification of Unique Antigenic Determinants in the Amino Terminus of IA-2 (ICA512) in Childhood and Adult Autoimmune Diabetes: New Biomarker Development. Diabetes Care 2017;40:561-568. PMID: 28174261.

2. Agarwal N, Iyer D, Gabbi C, Saha P, Patel SG, Mo Q, Chang B, Goswami B, Schubert U, Kopp JB, Lewis DE, Balasubramanyam A. HIV-1 viral protein R (Vpr) induces fatty liver in mice via LXRα and PPARα dysregulation: implications for HIV-specific pathogenesis of NAFLD. Scientific Reports 2017;7:13362. PMID: 29042644

3. Aguirre LE, Colleluori G, Dorin R, Robbins D, Chen R, Jiang B, Qualls C, Villareal DT, Armamento-Villareal R. Hypogonadal Men with Higher Body Mass Index have Higher Bone Density and Better Bone Quality but Reduced Muscle Density. Calcif Tissue Int. 2017;101:602. PMID:28856390

4. Bader DA, Hartig SM, Putluri V, Foley C, Hamilton MP, Smith EA, Saha P, Panigrahi A, Walker C, Zong L, Martini-Stoica H, Chen R, Rajapakshe K, Coarfa C, Sreekumar A, Mitsiades N, Bankson JA, Ittmann MM, Putluri N, McGuire SE. “Mitochondrial Pyruvate Import is a Metabolic Vulnerability in Prostate Adenocarcinoma,” Nat Met 2018. In press

5. Bai S, Fu K, Yin H, Cui Y, Yue Q, Li W, Cheng L, Tan H, Liu X, Guo Y, Zhang Y, Xie J, He W, Wang Y, Feng H, Xin C, Zhang J, Lin M, Shen B, Sun Z, Guo X, Zheng K, Ye L. Sox30 initiates transcription of haploid genes during late meiosis and spermiogenesis in mouse testes. Development 2018;145 PMID: 29866902

6. Batsis JA and Villareal DT. Sarcopenic obesity in older adults: aetiology, epidemiology, and treatment strategies. Nat Rev Endocrinology 2018;14:513. PMID: 30065268

7. Birnbaum Y, Bajaj M, Yang HC, Ye Y. Combined SGLT2 and DPP4 Inhibition Reduces the Activation of the Nlrp3/ASC Inflammasome and Attenuates the Development of Diabetic Nephropathy in Mice with Type 2 Diabetes. Diabetes Cardiovasc Drugs Ther 2018;32:135. PMID: 29508169

8. Birnbaum Y, Ye Y, Bajaj M. Type 2 Diabetes and CVD: A Metabolic Overview of Recent Clinical Trials. J Diabetes Complications 2017;31:291. PMID: 27780670

9. Bloomgarden Z, Einhorn D, Handelsman Y, Misra A, Zonszein J, Grunberger G, Jellinger PS, Garber AJ. ACP diabetes guidelines attempt to turn back the clock, conflating good HbA1c with hypoglycemia. J Diabetes 2018 PMID: 29655268 [Epub ahead of print]

10. Cieslik KA, Sekhar RV, Granillo A, Reddy A, Medrano G, Heredia CP, Entman ML, Hamilton DJ, Li S, Reineke E, Gupte AA, Zhang A, Taffet GE. Improved Cardiovascular Function in Old Mice After N-Acetyl Cysteine and Glycine Supplemented Diet: Inflammation and Mitochondrial Factors. J Gerontol A Biol Sci Med Sci 2018;73:1167. PMID: 29538624

of 18

11. Chen E, Tsai TH, Li L, Saha P, Chan L, Chang BH. PLIN2 is a Key Regulator of

the Unfolded Protein Response and Endoplasmic Reticulum Stress Resolution in Pancreatic β Cells. Scientific Reports. 2017;7:40855. PMID: 28102311

12. Chen Y, Chen H, Birnbaum Y, Nanhwan MK, Bajaj M, Ye Y, Qian J. Aleglitazar, a dual PPARα and PPARγ agonist, protects cardiomyocytes against the adverse effects of hyperglycemia. Diab Vasc Dis Res 2017;14:152. PMID 28111985

13. Colleluori G, Aguirre L, Dorin R, Robbins D, Blevins D, Barnouin Y, Chen R, Qualls C, Villareal DT, Armamento-Villareal R. Hypogonadal men with type 2 diabetes mellitus have smaller bone size and lower bone turnover. Bone 2017;99:14. PMID: 28323146

14. Colleluori G, Chen, R., Napoli N , Aguirre LE, Qualls C, Villareal DT, Armamento-Villareal R, Fat Mass Follows a U-Shaped Distribution Based on Estradiol Levels in Postmenopausal Women. Frontiers in Endocrinology, Front Endocrinol (Lausanne) 2018;9:315. PMID: 30013511

15. Colleluori G, Napoli N, Phadnis U, Armamento-Villareal RC, Villareal DT. Effect of weight loss, exercise, or both on undercarboxylated osteocalcin and insulin secretion in frail, obese older adults. Oxid Med Cell Longev 2017;4807046. PMID: 28951766

16. Cui C, Jiang X, Ju W, Wang J, Wang D, Sun Z, Chen M. Atrial remodeling and metabolic dysfunction in idiopathic isolated fibrotic atrial cardiomyopathy. Int J Cardiol. 2018;265:155. PMID: 29706431

17. Duerrschmid C, He Y, Wang C, Li C, Bournat JC, Romere C, Saha PK, Lee ME, Phillips KJ, Jain M, Jia P, Zhao Z, Farias M, Wu Q, Milewicz DM, Sutton VR, Moore DD, Butte NF, Krashes MJ, Xu Y, Chopra AR. Asprosin is a centrally acting orexigenic hormone. Nat Med 2017; 23:1444. PMID: 29106398

18. Fonseca VA, Bloomgarden ZT, Dagogo-Jack S, Grunberger G, Einhorn D, Garber AJ, Handelsman Y, Hirsch IB, Umpierrez GE. AACE Position Statement on the Use of Follow-On Biologics and Biosimilars for Endocrine Diseases. Endocr Pract 2017;23:1345. PMID: 29190135

19. Foster JG, Wood SK, Pfeffer MA, DeMets DL, Garber AJ, Hennekens CH. Aspirin in Primary Prevention for Patients with Type 2 Diabetes. Endocr Pract. 2018 July 5. PMID: 29975578 [Epub ahead of print]

20. Galvan DL, Badal SS, Long J, Chang BH-J, Schumacker PT, Overbeek PA, Danesh FR. Real-time in vivo mitochondrial redox assessment confirms enhanced mitochondrial reactive oxygen species in diabetic nephropathy. Kidney Int. 2017;92:1282. PMID: 28754553

21. Garber AJ, Abrahamson MJ, Barzilay JJ, Blonde L, Bloomgarden ZT, Bush MA, Dagogo-Jack S, DeFronzo RA, Einhorn D, Fonseca VA, Garber JR, Garvey WT, Grunberger G, Handelsman Y, Henry RR, Hirsch IB, Jellinger PS, McGill JB, Mechanick JI, MD, Rosenblit PD, and Umpierrez GE. Consensus Statement by the American Association of Clinical Endocrinologists and the American College of Endocrinology on the Comprehensive Type 2 Diabetes Management Algorithm – 2017 Executive Summary. Endocr Pract. 2017;23:207. PMID: 28095040

of 18

22. Garber AJ, Abrahamson MJ, Barzilay JJ, Blonde L, Bloomgarden ZT, Bush MA, Dagogo-Jack S, DeFronzo RA, Einhorn D, Fonseca VA, Garber JR, Garvey WT, Grunberger G, Handelsman Y, Henry RR, Hirsch IB, Jellinger PS, McGill JB, Mechanick JI, MD, Rosenblit PD, and Umpierrez GE. American Association of Clinical Endocrinologists and the American College of Endocrinology Comprehensive Type 2 Diabetes Management Algorithm, Consensus Statement and Executive Summary - 2018. Endocr Pract. 2018;24:91. PMID: 29368965

23. Garcia JM, Biller BMK, Korbonits M, Popovic V, Luger A, Strasburger CJ, Chanson P, Swerdloff RS, Pekic-Djurdjevic R, Blevins TC, Marcelli M, Medic M, Schopohl J, Ammer N, Sachse R and Yuen KCJ Validation of Macimorelin as a Diagnostic Test for Adult Growth Hormone Deficiency (AGHD): A Phase 3 Study in Comparison with the Insulin Tolerance Test (ITT). J Clin Endocrinol Metab 2018;103:3083. PMID 29860473

24. Gong Y, Cao R, Ding G, Hong S, Zhou W, Lu W, Damle M, Fang B, Wang CC, Qian J, Lie N, Lanzillotta C, Rabinowitz JD, Sun Z. Integrated omics approaches to characterize a nuclear receptor corepressor-associated histone deacetylase in mouse skeletal muscle. Mol Cell Endocrinol. 2018;471:22. PMID:28554803

25. Grunberger G, Handelsman Y, Bloomgarden ZT, Fonseca VA, Garber AJ, Haas RA, Roberts VL, Umpierrez GE. American Association of Clinical Endocrinologists and the American College of Endocrinology 2018 Position Statement on Integration of Insulin Pumps and Continuous Glucose Monitoring in Patients with Diabetes Mellitus. Endocr Pract 2018;24:302. PMID: 295547046

26. Hong S, Zhou W, Fang B, Lu W, Loro E, Damle M, Ding G, Jager J, Zhang S, Zhang Y, Feng D, Chu Q, Dill BD, Molina H, Khurana TS, Rabinowitz JD, Lazar MA, Sun Z. Dissociation of muscle insulin sensitivity from exercise endurance in mice by HDAC3 depletion. Nat Med 2017;23:223. PMID: 27991918

27. James EA, Pietropaolo M, Mamula MJ. Immune recognition of β-Cells: Neoepitopes as key players in the loss of tolerance. Diabetes. 2018;67:1035. PMID: 29784651

28. Jellinger P, Handelsman Y, Bell D, Bloomgarden Z, Brinton E, Davidson M, Fazio S, Fonseca V, Garber A, Grunberger G, Guerin C, Mechanick J, Pessah-Pollack R, Rosenblit P, Smith D, and Wyne K. AACE/ACE Guidelines for Management of Dyslipidemia and Prevention of Cardiovascular Disease. Endocr Pract. 2017;23:479. PMID: 2815615

29. Jia X, Alam M, Ye Y, Bajaj M, Birnbaum Y. GLP-1 Receptor Agonists and Cardiovascular Disease: a Meta-Analysis of Recent Cardiac Outcome Trials. Cardiovasc Drugs Ther 2018;32:65. PMID: 29445896

30. Jiang BC, Cowart JB, Barshes NR. Acute kidney injury associated with foot osteomyelitis. Clin Med 2017;17:376. PMID: 28765424.

31. Jois T, Chen W, Howard V, Harvey R, Youngs K, Thalmann C, Saha P, Chan L, Cowley MA, Sleeman MW. Deletion of hepatic carbohydrate response element binding protein (ChREBP) impairs glucose homeostasis and hepatic insulin sensitivity in mice. Mol Metabolism 2017; 6:1381. PMID: 29107286

32. Kim J, Kim J, Kwak MJ, Bajaj M. Genetic prediction of type 2 diabetes using deep neural network. Clin Genet. 2018;93:822. PMID: 29136281

of 18

33. Kim KH, Choi S, Zhou Y, Kim EY, Lee JM, Saha PK, Anakk S, Moore DD. Hepatic FXR/SHP axis modulates systemic glucose and fatty acid homeostasis in aged mice. Hepatology. 2017; 66:498. PMID: 28378930

34. Koh EH, Chernis N, Saha PK, Xiao L, Bader DA, Zhu B, Rajapakshe K, Hamilton MP, Liu X, Perera D, Chen X, York B, Trauner M, Coarfa C, Bajaj M, Moore DD, Deng T, McGuire SE, Hartig SM. miR-30a Remodels Subcutaneous Adipose Tissue Inflammation to Improve Insulin Sensitivity in Obesity. Diabetes 2018; PMID: 30002134 In Press

35. Maldonado M, Molfese DL, Viswanath H, Curtis K, Jones A, Hayes TG, Marcelli M, Mediwala S, Baldwin P, Garcia JM, Salas R. The habenula as a novel link between the homeostatic and hedonic pathways in cancer-associated weight loss: a pilot study. J Cachexia Sarc and Muscle 2018;9:497. PMID: 29575771

36. Mansueto G, Armani A, Viscomi C, D'Orsi L, De Cegli R, Polishchuk EV, Lamperti C, Di Meo I, Romanello V, Marchet S, Saha PK, Zong H, Blaauw B, Solagna F, Tezze C, Grumati P, Bonaldo P, Pessin JE, Zeviani M, Sandri M, Ballabio A. Transcription Factor EB Controls Metabolic Flexibility during Exercise. Cell Metabolism 2017;25:182. PMID: 28011087

37. Mitre TM, Pietropaolo M, Khadra A. The dual role of autoimmune regulator in maintaining normal expression level of tissue-restricted autoantigen in the thymus: A modeling investigation. Math Biosci 2017;287:12. PMID: 27765528

38. Mulukutla SN, Hsu JW, Gaba R, Bohren KM, Guthikonda A, Iyer D, Ajami NJ, Petrosino JF, Hampe CS, Ram N, Jahoor F, Balasubramanyam A. J Nutr Arginine Metabolism Is Altered in Adults with A-β + Ketosis-Prone Diabetes 2018;148:185. PMID: 29490093

39. Pahor, M., Kritchevsky, S.B., Waters, D.L., Villareal, D.T., Morley, J., Hare, J.M., and Vellas, B. Designing Drug Trials for Frailty: ICFSR Task Force 2018. J Frailty Aging 2018;7:150. PMID: 30095144

40. Pradhan G, Wu C-S, Lee JH, Kanikarla P, Guo S, Yechoor V, Samson S, Sun Y. Obestatin stimulates glucose-induced insulin secretion through ghrelin receptor GHS-R. Nature Scientific Reports 2017;7:929. PMID: 28428639

41. Poleshko A, Shah PP, Gupta M, Babu A, Morley MP, Manderfield LJ, Ifkovits JL, Calderon D, Aghajanian H, Sierra-Pagán JE, Sun Z, Wang Q, Li L, Dubois NC, Morrisey EE, Lazar MA, Smith CL, Epstein JA, Jain R. Genome-Nuclear Lamina Interactions Regulate Cardiac Stem Cell Lineage Restriction. Cell 2017;171:573. PMID: 29033129

42. Racette SB, Rochon J, Uhrich ML, Villareal DT, Das SK, Fontana L, Bhapkar M, Martin CK, Redman LM, Fuss PJ, Roberets SV, Kraus WE. Effects of two years of calorie restriction on aerobic capacity and muscle strength. Med Sci Sports Exerc 2017;49:2240. PMID: 29045325

43. Swift LL, Love JD, Harris CM, Chang BH-J, Jerome WG. 2017. Microsomal triglyceride transfer protein contributes to lipid droplet maturation in adipocytes. PLoS One. 12:e0181046. PMID: 28793320

44. Szafran TA, Marcelli M, Mancini MA High content screening of a library of 145 FDA approved drugs for the identification of novel inhibitors of AR and AR variant-7 The Prostate 2017;77:82. PMID: 27699828

https://www-ncbi-nlm-nih-gov.ezproxyhost.library.tmc.edu/pubmed/?term=Maldonado%20M%5BAuthor%5D&cauthor=true&cauthor_uid=29575771

https://www-ncbi-nlm-nih-gov.ezproxyhost.library.tmc.edu/pubmed/?term=Molfese%20DL%5BAuthor%5D&cauthor=true&cauthor_uid=29575771

https://www-ncbi-nlm-nih-gov.ezproxyhost.library.tmc.edu/pubmed/?term=Viswanath%20H%5BAuthor%5D&cauthor=true&cauthor_uid=29575771

https://www-ncbi-nlm-nih-gov.ezproxyhost.library.tmc.edu/pubmed/?term=Curtis%20K%5BAuthor%5D&cauthor=true&cauthor_uid=29575771

https://www-ncbi-nlm-nih-gov.ezproxyhost.library.tmc.edu/pubmed/?term=Jones%20A%5BAuthor%5D&cauthor=true&cauthor_uid=29575771

https://www-ncbi-nlm-nih-gov.ezproxyhost.library.tmc.edu/pubmed/?term=Hayes%20TG%5BAuthor%5D&cauthor=true&cauthor_uid=29575771

https://www-ncbi-nlm-nih-gov.ezproxyhost.library.tmc.edu/pubmed/?term=Marcelli%20M%5BAuthor%5D&cauthor=true&cauthor_uid=29575771

https://www-ncbi-nlm-nih-gov.ezproxyhost.library.tmc.edu/pubmed/?term=Marcelli%20M%5BAuthor%5D&cauthor=true&cauthor_uid=29575771

https://www-ncbi-nlm-nih-gov.ezproxyhost.library.tmc.edu/pubmed/?term=Mediwala%20S%5BAuthor%5D&cauthor=true&cauthor_uid=29575771

https://www-ncbi-nlm-nih-gov.ezproxyhost.library.tmc.edu/pubmed/?term=Baldwin%20P%5BAuthor%5D&cauthor=true&cauthor_uid=29575771

https://www-ncbi-nlm-nih-gov.ezproxyhost.library.tmc.edu/pubmed/?term=Garcia%20JM%5BAuthor%5D&cauthor=true&cauthor_uid=29575771

https://www-ncbi-nlm-nih-gov.ezproxyhost.library.tmc.edu/pubmed/?term=Salas%20R%5BAuthor%5D&cauthor=true&cauthor_uid=29575771

of 18

45. Tsai TH, Chen E, Li L, Saha P, Lee HJ, Huang LS, Shelness GS, Chan L, Chang BH. The constitutive lipid droplet protein PLIN2 regulates autophagy in liver. Autophagy. 2017; 13:1130. PMID: 28548876

46. Villareal DT, Waters DL, Qualls C. Exercise type in dieting obese older adults. N Engl J Med 2017;377:599. PMID: 28792874

47. Wei Q, Lee JH, Wang H, Bongmba OYN, Wu CS, Pradhan G, Sun Z, Chew L, Bajaj M, Chan L, Chapkin RS, Chen MH, Sun Y. Adiponectin is required for maintaining normal body temperature in a cold environment. BMC Physiol 2017;17:8. PMID: 29058611

48. Xiong M, Zhu Z, Tian S, Zhu R, Bai S, Fu K, Davis JG, Sun Z, Baur JA, Zheng K, Ye L. Conditional ablation of Raptor in the male germ line causes infertility due to meiotic arrest and impaired inactivation of sex chromosomes. FASEB J. 2017;31:3934 PMID: 28490482

49. Ye Y, Bajaj M, Yang HC, Perez-Polo JR, Birnbaum Y. SGLT-2 Inhibition with Dapagliflozin Reduces the Activation of the Nlrp3/ASC Inflammasome and Attenuates the Development of Diabetic Cardiomyopathy in Mice with Type 2 Diabetes. Further Augmentation of the Effects with Saxagliptin, a DPP4 Inhibitor. Cardiovasc Drugs Ther 2017;31:119. PMID: 28447181

50. Zhang L, Sosinowski T, Cox RA, Cepeda JR, Sekhar NS, Hartig SM, Miao D, Yu L, Pietropaolo M, Davidson HD. Chimeric antigen receptor (CAR) T cells targeting a pathogenic MHC class II:peptide complex modulate the progression of autoimmune diabetes. J Autoimmun In press

51. Zhang Y, Papazyan R, Damle M, Fang B, Jager J, Feng D, Peed LC, Guan D, Sun Z, Lazar MA. The hepatic circadian clock fine-tunes the lipogenic response to feeding through RORα/γ. Genes Dev 2017;31:1202. PMID: 28747429

52. Zhao N, Cao J, Xu L, Tang Q, Dobrolecki LE, Lyu X, Talukdar M, Lu Y, Wang X, Hu D, Shi Q, Xiang Y, Wang Y, Liu X, Bu W, Jiang Y, Li M, Gong Y, Sun Z, Ying H, Yuan B, Lin X, Feng XH, Hartig SM, Li F, Shen H, Chen Y, Han L, Zeng Q, Patterson J, Kaipparettu BA, Putluri N, Sicheri F, Rosen JM, Lewis MT, Chen X. Pharmacological Targeting of MYC-Regulated IRE1a/XBP1 Pathway Suppresses MYC-Driven Breast Cancer J Clin Invest 2018;128:1283. PMID: 29480818

of 18

B. Awards and Honors

1. Bajaj: Prof. Sevim Büyükdevrim Lecture, Turkish Diabetes Association 54th National Diabetes Congress, Antalya, Turkey.

2. Bajaj: The Best Doctors in America, Best Doctors 2017-18. 3. Bajaj: Top Doctors, Houstonia Magazine 2017 4. Garber: Albert Nelson Marquis Lifetime Achievement Award 5. Garber: Best Doctors in America 6. Garber: Master of the American College of Endocrinology 7. Garber: Who’s Who in the World 8. Hartig: Baylor College of Medicine Nominee, ADA Pathway to Stop

Diabetes Award 9. Marcelli: Best Doctors in America 10. Ram: Norton Rose Award in Teaching and Evaluation Spring 2018 11. Ram: Houston’s Top Physicians 2017 Castle Connolly 12. Sekhar: Second Place, Baylor Medicine Research Symposium, April 2018.

Optimal glycemic control may not be enough to prevent risk of diabetic complications – novel role of glutathione and oxidative stress

13. Sekhar: Second Place, Baylor Medicine Research Symposium, April 2018. Reversing accelerated aging in HIV patients - metabolic and mitochondrial mechanisms

14. Sekhar: Star Award For Excellence in Patient Care, Baylor College of Medicine, 2017.

15. R.Villareal: Research Award: “Certificate of Excellence”, Director’s Townhall Meeting, November 1, 2017, MEDVAMC.

16. Wang: AACR Workshop on Integrative Molecular Epidemiology, Boston, MA

of 18

C. Books and Book Chapters

1. Workeneh B, Bajaj M. Nutritional Considerations in Patients with Diabetes and Kidney Disease. In William E. Mitch and T. Alp Ikizler (Eds), Handbook of Nutrition and the Kidney, 7th Edition, Wolters Kluwer, 91-100, 2018.

2. Samson SL and Garber AJ, 2018: Type 2 Diabetes. In JL Chiasson (ed). Encyclopedia of Endocrine Diseases, 2nd Edition. Elsevier (in press).

3. Shah B and Samson SL. 2017. Hyponatremia. In, Conn’s Current Therapy (Bope ET and Kellerman RD, eds.), Elsevier.

4. Samson S and Garber A. 2018. Diabetes, Type 2. Huhtaniemi I, (ed.) In, Encyclopedia of Endocrine Diseases, 2nd Edition. In press, Elsevier

5. Sekhar RV Invitation from the American Academy of HIV Medicine (AAHIVM) to contribute two chapters for the 3rd Edition of the book ‘Fundamentals of HIV Medicine 2019’: The chapters are ‘Endocrine Disorders in HIV’ and ‘HIV lipodystrophy and lipoatrophy’.

6. Sekhar RV Invitation from Springer Nature Publications to contribute two Chapters to the ‘Encyclopedia of Gerontology and Population Aging 2019’. Chapters include ‘Human aging and metabolism’ and ‘Oxidation damage accumulation aging theory’

7. Marcelli M, “The androgen receptor” In Hohl A (ed) “Testosterone: From Basic to Clinical Aspects” Springer (NY) 2017, 21-73.

8. Mediwala SN, Marcelli M “Endocrine abnormalities in the HIV patient” in Shandera W (ed) “The Sub-Specialty Care of HIV-Infected Patients ” Nova Science Publishers. 2018. Chapter 6, pp129-174

https://www.novapublishers.com/catalog/product_info.php?products_id=63854

of 18

D. Professional Organization/Association Offices Held 1. Garber A: American Association of Clinical Endocrinologists 2. Garber A: American College of Endocrinology 3. Garber A: American Diabetes Association 4. Garber A: American Medical Association 5. Garber A: National Lipid Association 6. Garber A: The Endocrine Society 7. Garber A: AACE/ACE Committees/Task Forces

o Board of Directors o Advisor to the President o Lipids Scientific Committee o Obesity Scientific Committee o Obesity Resource Center o Chair, AACE/ACE Task Force to Update the Comprehensive Diabetes o Management Algorithm o Finance Committee o Diabetes Scientific Committee o Task Force on Consensus Conference on the Endocrinology of Aging o Task Force to Develop AACE’s Position on the Integration of Insulin

Pumps and Continuous Glucose Monitoring o Task Force to Update the Insulin Pump Management Consensus Statement o ACE Center for Transcultural Endocrinology Steering Committee o Nominating Committee o Task Force to Develop the AACE/ACE Lipids Algorithm o Chair, AACE Journals Task Force

8. Hartig S: Faculty, The Endocrine Society Career Development Workshop 9. Hartig S: Abstract reviewer, The Endocrine Society’s 100th Annual Meeting,

Chicago, IL 10. Hartig S: Ad-hoc member, NIH CSR Cellular Aspects of Diabetes and Obesity

Study Section (CADO) 11. Marcelli M: Abstract reviewer, The Endocrine Society’s 100th Annual Meeting,

Chicago, IL 12. Marcelli M: The Endocrine Society 13. Marcelli M: Elected member Southern Society of Medical Investigation 14. Pietropaolo M: Reviewer, Special Emphasis Panel (SEP) Study Section

[ZRG1-EMNR-B (50) M]. PAR-16-121: “Early-Stage Preclinical Validation of Therapeutic Leads for Diseases of Interest to the NIDDK (R01)” 3/2017.

15. Pietropaolo M: Reviewer for R01 and R21 grants. Kidney, Nutrition, Obesity and Diabetes Study Section (KNOD, NIDDK); 05/2018

16. Pietropaolo M: Chair, Immunology, Immunogenetics, & Transplantation Planning Committee for the 2018 National Conference of the American Diabetes Association, Orlando, FL.

of 18

17. Samson S: Elected Member, Board of Directors of the American Association of Clinical Endocrinologists

18. Samson S: Member, Board of Trustees, American College of Endocrinology 19. Samson S: Elected member, Council of the American Program Directors of

Endocrinology and Metabolism (APDEM) 20. Samson S: Member, American Board of Internal Medicine, Self-assessment

committee 21. Samson S: Member, American Board of Internal Medicine, Item-writing Task

Force 22. Samson S: Chair, American Association of Clinical Endocrinologists National

Congress Annual Program Committee Annual Congress, American Association of Clinical Endocrinologists

23. Samson S: Vice-Chair, Endocrine University Planning Committee of the American College of Endocrinology

24. Samson S: Member, Expert Group on Pituitary Tumors, The Pituitary Society 25. Samson S: Member, Committee for Professional Education, The Pituitary

Society 26. Villareal R: American Society for Bone and Mineral Research 27. Villareal R: The Endocrine Society 28. Villareal R: American Association of Clinical Endocrinologists 29. Villareal R: American College of Physicians 30. Villareal D: National Institute on Aging Clinical Trials Advisory Panel (CTAP) 31. Villareal D: Task Force on Sarcopenia and Frailty, International Conference on

Sarcopenia and Frailty, Miami, FL 32. Villareal D: Data and Safety Monitoring Board for the following NIH grant

projects a. “Maintenance of Skeletal Integrity in Frail Elders” (RO1-AG050302) b. “Skeletal Muscle and Insulin Resistance in Aging (RO1-AG021961);

Chairperson of the DSMB c. “Combining Testosterone Therapy to Improve Function Post Hip Fracture

(RO1 AG051647) 33. Villareal R: Empowered with Movement to Prevent Obesity & Weight Regain”

(RO1AG051624)

of 18

E. Editorial Board Memberships and Editorial Positions

1. Bajaj: Editorial Board, The Journal of Clinical Endocrinology and Metabolism 2. Bajaj: Associate Editor, British Medical Journal Open Diabetes Research and

Care 3. Garber: Editor, Endocrine Today 4. Garber: Editor (Emeritus), Diabetes, Obesity and Metabolism 5. Marcelli: Associate Editor: Journal of Investigative Medicine 6. Pietropaolo: Associate Editor, Diabetes 7. Pietropaolo: Associate Editor, PLoS ONE 8. Pietropaolo: Editorial Board, American Journal of Clinical and Experimental

Immunology 9. Pietropaolo: Editorial Board, Autoimmunity Highlights 10. Sun: Editor, Research Topic: Type 2 Diabetes Management: A Focus on

Metabolic Defects. Frontiers in Physiology. 2018 11. Villareal R: Associate Editor, Frontiers in Endocrinology 12. Villareal D: Associate Editor, Journal of Nutrition in Geriatrics and Gerontology 13. Villareal D: Academic Editor, Current Developments in Nutrition 14. Villareal D: Associate Editor, Journal of Gerontology – Medical Science 15. Villareal D: Section Editor: Obesity and Aging, Journal of Nutrition in Health and

Aging

of 18

F. Grants MEDICINE – ENDOCRINOLOGY

NIH Other Federal Non-Federal Cash Total

MEDICINE: ENDOCRINOLOGY $3,649,028.00 $0.00 $1,388,236.10 $67,906.80 $5,105,170.90

TOTALS $3,649,028.00 $0.00 $1,388,236.10 $67,906.80 $5,105,170.90

Grants and Contracts Awarded 07/01/2017 - 06/30/2018

Principal

Investigator

Sponsor Grant Number Project Title Budget Period

Project Period Total

BALASUBRAMANYAM, ASHOK

NATIONAL INSTITUTES OF HEALTH (NIH)

U01-DK098246-06

YEAR 6: THE GLYCEMIA REDUCTION APPROACHES IN DIABETES: A COMPARATIVE EFFECTIVENESS STUDY (GRADE)

9/6/2017 - 7/31/2018

9/25/2012 - 7/31/2022 $569,332.00



R33-AI116208-03 Amd 3

YR 4: ADIPOSE TISSUE IS A SIGNIFICANT RESERVOIR FOR HIV

9/1/2017 - 8/31/2018

9/1/2014 – 8/31/2019 $111,012.00

https://brain.bcm.edu/esp2/reports/AwardsDetail.asp?deptcode=223&centercode=&locationcode=&sectioncode=160&fromdate=07/01/2017&todate=06/30/2018&PIBCMID=&sponsor=&groupdesc=MEDICINE%20-%20ENDOCRINOLOGY&fundinginstruments=*C*,*A*,*G*,*N*,*O*,*T*,*S*&sortby=name


https://brain.bcm.edu/esp2/reports/AwardsDetail.asp?deptcode=223&centercode=&locationcode=&sectioncode=160&fromdate=07/01/2017&todate=06/30/2018&PIBCMID=&sponsor=&groupdesc=MEDICINE%20-%20ENDOCRINOLOGY&fundinginstruments=*C*,*A*,*G*,*N*,*O*,*T*,*S*&sortby=sponsor_desc

https://brain.bcm.edu/esp2/reports/AwardsDetail.asp?deptcode=223&centercode=&locationcode=&sectioncode=160&fromdate=07/01/2017&todate=06/30/2018&PIBCMID=&sponsor=&groupdesc=MEDICINE%20-%20ENDOCRINOLOGY&fundinginstruments=*C*,*A*,*G*,*N*,*O*,*T*,*S*&sortby=grant_protocol_number

of 18

Principal Investigator Sponsor Grant Number Project Title Budget

Period Project Period Total



R01-DK104832-03

(MPI) YEAR 3: ROLE OF ISLET INJURY AND AUTOIMMUNITY IN T2D BETA CELL DYSFUNCTION

9/1/2017 - 8/31/2018

9/16/2015 – 8/31/2020 $353,493.00

GARBER, ALAN J NOVO NORDISK, INC

023350 NCE

16TH ANNUAL SYMPOSIUM ON ADVANCED METABOLIC DISEASE MANAGEMENT FOR ENDOCRINE FELLOWS

6/1/2018 - 6/30/2018 ---- $0.00

GARBER, ALAN J NOVO NORDISK, INC

MED-DIA-24942

17TH ANNUAL SYMPOSIUM ON ADVANCED DIABETES MANAGEMENT FOR ENDOCRINE FELLOWS

6/21/2018 -

6/20/2019 ---- $345,000.00

MARCELLI, MARCO

SHIRE HUMAN GENETIC THERAPIES, INC.

IME-USA-17539 ENDOCRINE GRAND ROUNDS 10/4/2017

- 10/3/2018

---- $3,750.00

MARCELLI MARCO DEPARTMENT OF DEFENSE

W81XWH-17-1-0368 (Jorge R., PI)

PERSISTENT HORMONAL CHANGES IN VETERANS WITH GULF WAR ILLNESS

9/2017-9/2020 ---- $615,171.00





of 18



PIETROPAOLO, MASSIMO

CENTER FOR MEDICARE & MEDICAID INNOVATION (DHHS)

UC4-DK101108-01 Amd 4

YR 3/4: PERL - A MULTICENTER CLINICAL TRIAL OF ALLOPURINOL TO PREVENT GFR LOSS IN T1D.

8/1/2017 - 9/30/2017

8/1/2014 – 9/30/2017 $5,939.00



R01-DK053456-15A1

YEAR 15: ENHANCEMENT OF BIOMARKERS FOR TYPE 1 DIABETES

7/1/2017 - 6/30/2018

5/1/1999 – 6/30/2022 $668,366.00



UC4-DK101108 02

PERL-YR1(SPINO): A MULTICENTER CLINICAL TRIAL OF ALLOPURINOL TO PREVENT GFR LOSS IN T1D

9/1/2017 - 8/31/2018

9/30/2013 – 6/30/2019 $30,669.00

SAMSON, SUSAN LEANNE

NOVARTIS PHARMACEUTICALS CORP

NCE

THE EFFECT OF PASIREOTIDE AND COMBINATION WITH A GLUCAGON-LIKE PEPTIDE 1 RECEPTOR AGONIST ON ISLET FUNCTION AND STRUCTURE

12/30/2017 -

6/1/2020

12/30/2017 – 6/1/2020 $0.00

SEKHAR, RAJAGOPAL VISWANATH


R01-AG054131 02

AGE-RELATED MILD COGNITIVE IMPAIRMENT AND THE PROTECTIVE ROLE OF GLUTATHIONE: IMPLICATIONS FOR ALZHEIMER'S DISEASE

6/1/2018 - 5/31/2019

9/5/2017 – 5/31/2022 $477,413.00





of 18



SUN, ZHENG

AMERICAN HEART ASSOCIATION INC

16GRNT30970064 Yr2

OBESITY-EPIGENOME INTERACTION IN HEART FAILURE

7/1/2017 - 6/30/2018

7/1/2016 – 6/30/2018 $77,000.00

SUN, ZHENG


R01-ES027544-02

YEAR 2: GENDER-SPECIFIC EFFECTS OF ARSENIC IN DIABETES

3/1/2018 - 2/28/2019

3/1/2017 – 2/28/2022 $433,675.00

SUN, ZHENG


R21-CA215591-01

DE FACTO TARGET OF HISTONE DEACETYLASE INHIBITORS

9/1/2017 - 8/31/2018

9/1/2017 – 8/31/2019 $172,369.00

VILLAREAL, DENNIS T.


R01-DK109950-02

YR2 : DOES LIFESTYLE INTERVENTION IN OBESE OLDER ADULTS IMPROVE BONE QUALITY?

6/1/2018 - 5/31/2019

6/1/2017 – 5/31/2022 $681,558.00

VILLAREAL, REINA


R01-HD093047-01

AROMATASE INHIBITORS AND WEIGHT LOSS IN SEVERELY OBESE MEN WITH HYPOGONADISM

8/7/2017 - 5/31/2018

8/7/2017 – 5/31/2022 $387,081.00





of 18



VILLAREAL, DENNIS

VA MERIT REVIEW

1101 CX000906-01

TESTOSTERONE REPLACEMENT TO AUGMENT LIFESTYLE THERAPY IN OBESE OLDER VETERANS

01/1/15-12/31/18

---- $483, 794.00

ZHANG, LI

JUVENILE DIABETES RESEARCH FOUNDATION

2-SRA-2016-238-S-B Yr2

EVALUATION OF MONOCLONAL ANTIBODIES SPECIFICALLY TARGETING PATHOGENIC INSULIN/MHC II COMPLEXES FOR THE TREATMENT/PREVENTION OF TYPE 1 DIABETES

7/1/2017 - 6/30/2018

7/1/2016 – 6/30/2018 $250,067.10

Totals: $5,037,264.10





of 18

CASH AWARDS 7/1/2017 - 6/30/2018

Principal Investigator Sponsor Project Title Fiscal Year Total

BAJAJ, MANDEEP

AMYLIN PHARMACEUTICALS

EXSCEL (EXENATIDE STUDY OF CARDIOVASCULAR EVENT LOWERING TRIAL)- A RANDOMIZED, PLACEBO CONTROLLED CLINICAL TRIAL TO EVALUATE CARDIOVASCULAR OUTCOMES AFTER TREATMENT WITH EXENATIDE ONCE WEEKLY IN PATIENTS WITH TYPE 2 DIABETES MELLITUS.

2018 $3,692.31

BAJAJ, MANDEEP ASTRAZENECA THE EFFECT OF DAPAGLIFLOZIN ON

INFLAMMATION AND ENDOTHELIAL DYSFUCTION 2018 $32,461.54


CHIASMA, INC.

AMENDMENT:A PHASE 3, RANDOMIZED, OPEN-LABEL, ACTIVE CONTROLLED, MULTICENTER STUDY TO EVALUATE MAINTENANCE OF RESPONSE, SAFETY AND PATIENT REPORTED OUTCOMES IN ACROMEGALY PATIENTS TREATED WITH OCTREOTIDE CAPSULES, AND IN PATIENTS TREATED WITH STANDARD OF CARE PARENTERAL SOMATOSTATIN RECEPTOR LIGANDS WHO PREVIOUSLY TOLERATED AND DEMONSTRATED A BIOCHEMICAL CONTROL ON BOTH TREATMENTS

2018 $12,277.78


CHIASMA, INC.

A PHASE 3, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED, MULTICENTER STUDY TO EVALUATE SAFETY AND EFFICACY OF OCTREOTIDE CAPSULES IN PATIENTS WHO PREVIOUSLY TOLERATED AND DEMONSTRATED BIOCHEMICAL CONTROL ON INJECTABLE SOMATOSTATIN RECEPTOR LIGANDS (SRL) TREATMENT PROTOCOL OOC-ACM-303

2018 $8,500.00


NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES (NIDDK)

CLINICAL CENTER # 3 - EMOTIONAL DISTRESS IN A COMPARATIVE EFFECTIVENESS TRIAL OF DIABETES TREATMENTS (EDS) -SUB-STUDY OF GRADE

2018 $8,378.85

BAJAJ, MANDEEP

NOVO NORDISK PHARMACEUTICALS

EFFECT OF LIRAGLUTIDE TREATMENT ON GUT MICROBIOTA AND ADIPOSE TISSUE INFLAMMATION IN PATIENTS WITH TYPE 2 DIABETES MELLITUS

2018 ($1,230.77)


PROLOR BIOTECH, LTD

A PHASE 3, MULTICENTER STUDY DESIGNED TO EVALUATE THE EFFICACY AND SAFETY OF A LONG ACTING HGH PRODUCT (MOD-4023) IN ADULT SUBJECTS WITH GROWTH HORMONE DEFICIENCY (PROTOCOL NUMBER: CP-4-005)

2018 $4,827.09

$67,906.80

Grand Totals: $5,105,170.90

1

Epidemiology & Population Science

Baylor College of Medicine

Annual Report, Fiscal Year 2018

2

Faculty Epidemiology & Population Science Institute for Clinical and Translational Research Melissa Bondy, PhD Chris Amos, PhD Yanhong Liu, MS, PhD Younghun Han, PhD Margaret Spitz, MD Yafang Li, PhD Aaron Thrift, PhD Postdoctoral Fellows Jeremy Schraw, PhD Jing Dong, PhD Zhensheng Wang, MPH, PhD Quinn Ostrom, MPH, PhD Contents A. Publications ................................................................................................................... 3 B. Awards and Honors...................................................................................................... 22 C. Press ........................................................................................................................... 24 D. Books and Book Chapters............................................................................................ 23 E. Professional Organization/Association Offices Held ..................................................... 26 F. Editorial Board Memberships and Editorial Positions ................................................... 27 G. Grants .......................................................................................................................... 28

Department of Medicine, Baylor College of Medicine Section of Epidemiology & Population Science

(1 July 2017–30 June 2018)

3

A. Publications

Impact factors of journals for 127 published articles (mean 9.71) Journal Impact Factor: <= 3 3 - 6 6 - 10 10 - 20 20 - 30 >= 30 Published Articles: 18 32 46 9 13 9 Percentage of Total: 14.2% 25.2% 36.2% 7.1% 10.2% 7.1%

1. AM Musolf, CL Simpson, M Andrade, D Mandal, C Gaba, Yang P, Li Y, You M, Kupert,

EY, Anderson MW, Schwartz AG, Pinney SM, Amos CI, Bailey-Wilson JE. Parametric Linkage Analysis Identifies Five Novel Genome-wide Significant Loci for Familial Lung Cancer. Human Heredity 2017; 82(102): 64-74. IF: 0.542

2. Anderson JC, Butterly LF, Robinson CM, Weiss JE, Amos C, Srivastava A. Risk of Metachronous High-risk Adenomas and Large Serrated Polyps in Individuals With Serrated Polyps on Index Colonoscopy: Data from the New Hampshire Colonoscopy Registry. Gastroenterology. 2017 Sep 16. pii: S0016-5085(17)36151-6. doi: 10.1053/j.gastro.2017.09.011. IF: 20.773

3. Bailey MH, Tokheim C, Porta-Pardo E, Sengupta S, Bertrand D, Weerasinghe A, Colaprico A, Wendl MC, Kim J, Reardon B, Ng PK, Jeong KJ, Cao S, Wang Z, Gao J, Gao Q, Wang F, Liu EM, Mularoni L, Rubio-Perez C, Nagarajan N, Cortés-Ciriano I, Zhou DC, Liang WW, Hess JM, Yellapantula VD, Tamborero D, Gonzalez-Perez A, Suphavilai C, Ko JY, Khurana E, Park PJ, Van Allen EM, Liang H; MC3 Working Group; Cancer Genome Atlas Research NetworkA, Lawrence MS, Godzik A, Lopez-Bigas N, Stuart J, Wheeler D, Getz G, Chen K, Lazar AJ, Mills GB, Karchin R, Ding L. Comprehensive Characterization of Cancer Driver Genes and Mutations. Cell. 2018 Apr 5;173(2):371-385.e18. doi: 10.1016/j.cell.2018.02.060. PubMed PMID: 29625053. IF: 30.41

4. Balakrishnan M, El-Serag HB, Nguyen T, Hilal J, Kanwal F, Thrift AP. Obesity and risk of non-alcoholic fatty liver disease: a comparison of bioelectrical impedance analysis and conventionally-derived anthropometric measures. Clin Gastroenterol Hepatol 2017;15(12):1965-1967, PMID: 28642206 IF: 7.896

5. Benz LS, Wrensch MR, Schildkraut JM, Bondy ML, Warren JL, Wiemels JL, Claus EB. Quality of life after surgery for intracranial meningioma. Cancer. 2018 Jan 1;124(1):161-166. doi: 10.1002/cncr.30975. Epub 2017 Sep 13. PMID: 28902404 IF: 6.702

6. Berger AC, Korkut A, Kanchi RS, Hegde AM, Lenoir W, Liu W, Liu Y, Fan H, Shen H, Ravikumar V, Rao A, Schultz A, Li X, Sumazin P, Williams C, Mestdagh P, Gunaratne PH, Yau C, Bowlby R, Robertson AG, Tiezzi DG, Wang C, Cherniack AD, Godwin AK, Kuderer NM, Rader JS, Zuna RE, Sood AK, Lazar AJ, Ojesina AI, Adebamowo C, Adebamowo SN, Baggerly KA, Chen TW, Chiu HS, Lefever S, Liu L, MacKenzie K, Orsulic S, Roszik J, Shelley CS, Song Q, Vellano CP, Wentzensen N; Cancer Genome Atlas Research NetworkA, Weinstein JN, Mills GB, Levine DA, Akbani R. A Comprehensive Pan-Cancer Molecular Study of Gynecologic and Breast Cancers. Cancer Cell. 2018 Apr 9;33(4):690-705.e9. doi: 10.1016/j.ccell.2018.03.014. Epub 2018 Apr 2. PubMed PMID: 29622464. IF: 27.407

7. Berntsson SG, Merrell RT, Amirian ES, Armstrong GN, Lachance D, Smits A, Zhou R, Jacobs DI, Wrensch MR, Olson SH, Il'yasova D, Claus EB, Barnholtz-Sloan JS, Schildkraut J, Sadetzki S, Johansen C, Houlston RS, Jenkins RB, Bernstein JL, Lai R,

4

Shete S, Amos CI, Bondy ML, Melin BS. Glioma-related seizures in relation to histopathological subtypes: a report from the glioma international case-control study. J Neurol. 2018 Jun; 265(6):1432-1442. doi: 10.1007/s00415-018-8857-0. Epub 2018 Apr 23. PMID: 29687214 IF: 3.578

8. Buas MF, He Q, Johnson LG, Onstad L, Levine DM, Thrift AP, Gharahkhani P, Palles C, Lagergren J, Fitzgerald RC, Ye W, Caldas C, Bird NC, Shaheen NJ, Bernstein L, Gammon MD, Wu AH, Hardie LJ, Pharoah PD, Liu G, Iyer P, Corley DA, Risch HA, Chow WH, Prenen H, Chegwidden L, Love S, Attwood S, Moayyedi P, MacDonald D, Harrison R, Watson P, Barr H, deCaestecker J, Tomlinson I, Jankowski J, Whiteman DC, MacGregor S, Vaughan TL, Madeleine MM. Germline variation in inflammation-related pathways and risk of Barrett’s oesophagus and oesophageal adenocarcinoma. Gut 2017;66(10):1739-1747, PMID: 27486097 IF: 16.658

9. Byun J, Han Y, Gorlov IP, Busam JA, Seldin MF, Amos CI. Ancestry inference using principal component analysis and spatial analysis: a distance-based analysis to account for population substructure. BMC Genomics. 2017 Oct 16;18(1):789. doi: 10.1186/s12864-017-4166-8. IF: 3.729

10. Byun J, Schwartz AG, Lusk C, Wenzlaff AS, de Andrade M, Mandal D, Gaba C, Yang P, You M, Kupert EY, Anderson MW, Han Y, Li Y, Qian D, Stilp A, Laurie C, Nelson S, Zheng W, Hung RJ, Gaborieau V, Mckay J, Brennan P, Caporaso NE, Landi MT, Wu X, McLaughlin JR, Brhane Y, Bossé Y, Pinney SM, Bailey-Wilson JE, Amos CI. Genome-Wide Association Study of Familial Lung Cancer.Carcinogenesis. 2018 Jun 19. doi: 10.1093/carcin/bgy080. PMID: 29924316 IF: 5.334

11. Campbell JD, Yau C, Bowlby R, Liu Y, Brennan K, Fan H, Taylor AM, Wang C, Walter V, Akbani R, Byers LA, Creighton CJ, Coarfa C, Shih J, Cherniack AD, Gevaert O, Prunello M, Shen H, Anur P, Chen J, Cheng H, Hayes DN, Bullman S, Pedamallu CS, Ojesina AI, Sadeghi S, Mungall KL, Robertson AG, Benz C, Schultz A, Kanchi RS, Gay CM, Hegde A, Diao L, Wang J, Ma W, Sumazin P, Chiu HS, Chen TW, Gunaratne P, Donehower L, Rader JS, Zuna R, Al-Ahmadie H, Lazar AJ, Flores ER, Tsai KY, Zhou JH, Rustgi AK, Drill E, Shen R, Wong CK; Cancer Genome Atlas Research NetworkA, Stuart JM, Laird PW, Hoadley KA, Weinstein JN, Peto M, Pickering CR, Chen Z, Van Waes C. Genomic, Pathway Network, and Immunologic Features Distinguishing Squamous Carcinomas. Cell Rep. 2018 Apr 3;23(1):194-212.e6. doi: 10.1016/j.celrep.2018.03.063. PubMed PMID: 29617660. IF: 8.282

12. Chen H, Li C, Peng X, Zhou Z, Weinstein JN; Cancer Genome Atlas Research NetworkA, Liang H. A Pan-Cancer Analysis of Enhancer Expression in Nearly 9000 Patient Samples. Cell. 2018 Apr 5;173(2):386-399.e12. doi: 10.1016/j.cell.2018.03.027. PubMed PMID: 29625054; PubMed Central PMCID: PMC5890960. IF: 30.410

13. Chiu HS, Somvanshi S, Patel E, Chen TW, Singh VP, Zorman B, Patil SL, Pan Y, Chatterjee SS; Cancer Genome Atlas Research NetworkA, Sood AK, Gunaratne PH, Sumazin P. Pan-Cancer Analysis of lncRNA Regulation Supports Their Targeting of Cancer Genes in Each Tumor Context. Cell Rep. 2018 Apr 3;23(1):297-312.e12. doi: 10.1016/j.celrep.2018.03.064. PubMed PMID: 29617668. IF: 8.282

14. Cotton CC, Haidry R, Thrift AP, Lovat L, Shaheen NJ. Development of evidence based surveillance intervals following radiofrequency ablation of Barrett’s esophagus. Gastroenterology. 12 April 2018 doi: 10.1053/j.gastro.2018.04.011. [Epub ahead of print], PMID: 29655833 IF: 20.773

15. David Qian, DL Molfese, JL Jennifer, AJ Titus, Y He, Y Li, M Vaisie, H Viswanath, PR

5

Baldwin, R Krahe, R Salas, CI Amos. Genome-wide imaging association study implicates functional activity and glial homeostasis of the caudate in smoking addiction. BMC Genomics 2017; 18:740. https://doi.org/10.1186/s12864-017-4124-5 IF: 3.729

16. DI Jacobs, Liu Y * (co-first), et al. Germline polymorphisms in myeloid-associated genes are not associated with glioma survival. J Neuro-Oncol, 2017; PMID:28965162 IF: 2.980

17. Dimitrakopoulou VI, Tsilidis KK, Haycock PC, Dimou NL, Al-Dabhani K, Martin RM, Lewis SJ, Gunter MJ, Mondul A, Shui IM, Theodoratou E, Nimptsch K, Lindström S, Albanes D, Kühn T, Key TJ, Travis RC, Vimaleswaran KS; GECCO Consortium; PRACTICAL Consortium; GAME-ON Network (CORECT, DRIVE, ELLIPSE, FOCI-OCAC, TRICL-ILCCO)C, Kraft P, Pierce BL, Schildkraut JM. Circulating vitamin D concentration and risk of seven cancers: Mendelian randomisation study. BMJ. 2017 Oct 31;359:j4761. doi: 10.1136/bmj.j4761 IF: 23.295

18. Ding L, Bailey MH, Porta-Pardo E, Thorsson V, Colaprico A, Bertrand D, Gibbs DL, Weerasinghe A, Huang KL, Tokheim C, Cortés-Ciriano I, Jayasinghe R, Chen F, Yu L, Sun S, Olsen C, Kim J, Taylor AM, Cherniack AD, Akbani R, Suphavilai C, Nagarajan N, Stuart JM, Mills GB, Wyczalkowski MA, Vincent BG, Hutter CM, Zenklusen JC, Hoadley KA, Wendl MC, Shmulevich L, Lazar AJ, Wheeler DA, Getz G; Cancer Genome Atlas Research NetworkA. Perspective on Oncogenic Processes at the End of the Beginning of Cancer Genomics. Cell. 2018 Apr 5;173(2):305-320.e10. doi: 10.1016/j.cell.2018.03.033. PubMed PMID: 29625049. IF: 30.410

19. Disney-Hogg L, Cornish AJ, Sud A, Law PJ, Kinnersley B, Jacobs DI, Ostrom QT, Labreche K, Eckel-Passow JE, Armstrong GN, Claus EB, Il'yasova D, Schildkraut J, Barnholtz-Sloan JS, Olson SH, Bernstein JL, Lai RK, Schoemaker MJ, Simon M, Hoffmann P, Nöthen MM, Jöckel KH, Chanock S, Rajaraman P, Johansen C, Jenkins RB, Melin BS, Wrensch MR, Sanson M, Bondy ML, Houlston RS. Impact of atopy on risk of glioma: a Mendelian randomisation study. BMC Med. 2018 Mar 15;16(1):42. doi: 10.1186/s12916-018-1027-5. PMID: 29540232 IF: 9.088

20. Disney-Hogg L, Sud A, Law PJ, Cornish AJ, Kinnersley B, Ostrom QT, Labreche K, Eckel-Passow JE, Armstrong GN, Claus EB, Il'yasova D, Schildkraut J, Barnholtz-Sloan JS, Olson SH, Bernstein JL, Lai RK, Swerdlow AJ, Simon M, Hoffmann P, Nöthen MM, Jöckel KH, Chanock S, Rajaraman P, Johansen C, Jenkins RB, Melin BS, Wrensch MR, Sanson M, Bondy ML, Houlston RS. Influence of obesity-related risk factors in the aetiology of glioma. Br J Cancer. 2018 Apr;118(7):1020-1027. doi: 10.1038/s41416-018-0009-x. Epub 2018 Mar 13. PMID: 29531326 IF: 6.176

21. Dixon-Suen SC, Nagle CM, Thrift AP, Pharoah PDP, Ewing A, Pearce CL, Zheng W; Australian Ovarian Cancer Study Group, Chenevix-Trench G, Fasching PA, Beckmann MW, Lambrechts D, Vergote I, Lambrechts S, Van Nieuwenhuysen E, Rossing MA, Doherty JA, Wicklund KG, Chang-Claude J, Jung AY, Moysich KB, Odunsi K, Goodman MT, Wilkens LR, Thompson PJ, Shvetsov YB, Dörk T, Park-Simon TW, Hillemanns P, Bogdanova N, Butzow R, Nevanlinna H, Pelttari LM, Leminen A, Modugno F, Ness RB, Edwards RP, Kelley JL, Heitz F, du Bois A, Harter P, Schwaab I, Karlan BY, Lester J, Orsulic S, Rimel BJ, Kjær SK, Høgdall E, Jensen A, Goode EL, Fridley BL, Cunningham JM, Winham SJ, Giles GG, Bruinsma F, Milne RL, Southey MC, Hildebrandt MAT, Wu X, Lu KH, Liang D, Levine DA, Bisogna M, Schildkraut JM, Berchuck A, Cramer DW, Terry KL, Bandera EV, Olson SH, Salvesen HB, Thomsen LCV, Kopperud RK, Bjorge L, Kiemeney LA, Massuger LFAG, Pejovic T, Bruegl A, Cook LS, Le ND, Swenerton KD, Brooks-Wilson A, Kelemen LE, Lubiński J, Huzarski T, Gronwald J, Menkiszak J,

6

Wentzensen N, Brinton L, Yang H, Lissowska J, Høgdall CK, Lundvall L, Song H, Tyrer JP, Campbell I, Eccles D, Paul J, Glasspool R, Siddiqui N, Whittemore AS, Sieh W, McGuire V, Rothstein JH, Narod SA, Phelan C, Risch HA, McLaughlin JR, Anton-Culver H, Ziogas A, Menon U, Gayther SA, Ramus SJ, Gentry-Maharaj A, Wu AH, Pike MC, Tseng CC, Kupryjanczyk J, Dansonka-Mieszkowska A, Budzilowska A, Rzepecka IK, Webb PM; Ovarian Cancer Association Consortium. Adult height is associated with increased risk of ovarian cancer: a Mendelian randomisation study. Br J Cancer 2018;118(8):1123-1129, PMID: 29555990 IF: 6.176

22. Dong J*, Levine DM*, Buas MF, Zhang R, Onstad L, Fitzgerald RC, Corley DA, Shaheen NJ, Lagergren J, Hardie LJ, Reid BJ, Iyer PG, Risch HA, Caldas C, Caldas I, Pharoah PD, Liu G, Gammon MD, Chow W-H, Bernstein L, Bird NC, Ye W, Wu AH, Anderson LA, Whiteman DC, Vaughan TL, Thrift AP. Interactions between genetic variants and environmental factors affect risk of esophageal adenocarcinoma and Barrett’s esophagus. Clin Gastroenterol Hepatol. 15 Mar 2018 doi: 10.1016/j.cgh.2018.03.007. [Epub ahead of print], PMID: 29551738 IF: 7.896

23. Dong J, Buas M, Gharahkhani P, Kendall B, Onstad L, Zhao S, Anderson L, Wu A, Ye W, Bird N, Bernstein L, Chow W, Gammon M, Liu G, Caldas C, Pharoah P, Risch H, Iyer P, Reid B, Hardie L, Lagergren J, Shaheen N, Corley A, Fitzgerald R, Whiteman D, Vaughan T, Thrift A. Determining Risk of Barrett's Esophagus and Esophageal Adenocarcinoma Based on Epidemiologic Factors and Genetic Variants. Gastroenterology 2018 Apr;154(5):1273-1281. IF: 20.773

24. Dong J, Cheng Y, Zhu M, Wen Y,Wang C, Wang Y, Geng L, Shen W, Liu J, Li Z, Zhang J, Ma H, Dai J, Jin G, Hu Z, Shen H. Fine Mapping of Chromosome 5p15.33 Identifies Novel Lung Cancer Susceptibility Loci in Han Chinese. Int J Cancer. 2017 Aug 1;141(3):447-456. IF: 6.513

25. Dong J, Gu X, El-Serag HB, Thrift AP. Underuse of Surgery Accounts for Racial Disparities in Esophageal Cancer Survival Times: A Matched Cohort Study. Clin Gastroenterol Hepatol. 2018 Jul 20. pii: S1542-3565(18)30742-0. doi: 10.1016/j.cgh.2018.07.018. [Epub ahead of print] PubMed PMID: 30036643.

26. Dong J, Pinto J, Guo X, Alonso A, Tranah G, Cauley J, Garcia M, Satterfield S, Huang X, Harris T, Mosley Jr. T, Chen H. The prevalence of anosmia and associated factors among U.S. black and white older adults. J Gerontol A Biol Sci Med Sci. 2017 Aug 1;72(8):1080-1086. IF: 4.902

27. Dong J, Thrift AP. Alcohol, smoking and risk of oesophago-gastric cancer. Best Pract Res Clin Gastroenterol 2017;31(5):509-517, PMID: 29195670 IF: 3.632

28. Dong J, Wong LJ, Mims MP. Mitochondrial inheritance and cancer. Transl Res. 2018 Jun 25. pii: S1931-5244(18)30100-2. doi: 10.1016/j.trsl.2018.06.004. [Epub ahead of print] Review. PubMed PMID: 30044960.

29. Dong J, Wyss A, Yang J, Price R, Nicolas A, Nalls M, Tranah G, Franceschini N, Xu Z, Schulte C, Alonso A, Cummings S, Fornage M, Zaykin D, Li L, Huang X, Kritchevsky S, Liu Y, Gasser T, Wilson R, De Jager P, Singleton A, Pinto J, Harris T, Mosley Jr. T, Bennett D, Stephanie London S, Yu L, Chen H. Genome-Wide Association Analysis of the Sense of Smell in U.S. Older Adults: Identification of Novel Risk Loci in African-Americans and European-Americans. Mol Neurobiol. 2017 Dec;54(10):8021-8032. IF: 5.076

30. E Mostovenko, Liu Y, ES Amirian, Tsavachidis S., Armstrong GN, Bondy ML, Nilsson CL. A Combined Proteomic-Molecular Epidemiology Approach to Identify Precision Targets in Brain Cancer. ACS Chemical Neuroscience 2017; PMID: 28657708. IF: 3.883

7

31. Ellrott K, Bailey MH, Saksena G, Covington KR, Kandoth C, Stewart C, Hess J, Ma S, Chiotti KE, McLellan M, Sofia HJ, Hutter C, Getz G, Wheeler D, Ding L; MC3 Working Group; Cancer Genome Atlas Research NetworkA. Scalable Open Science Approach for Mutation Calling of Tumor Exomes Using Multiple Genomic Pipelines. Cell Syst. 2018 Mar 28;6(3):271-281.e7. doi: 10.1016/j.cels.2018.03.002. PubMed PMID: 29596782. IF: 8.982

32. Fang S, Wang Y, Dang Y, Gagel A, Ross MI, Gershenwald JE, Cormier JN, Wargo J, Haydu LE, Davies MA, McQuade JL, Sui D, Bassett RL, Reveille JD, Wei Q, Amos CI, Lee JE. Association between Body Mass Index, C-Reactive Protein Levels, and Melanoma Patient Outcomes. J Invest Dermatol. 2017 Aug;137(8):1792-1795. doi: 10.1016/j.jid.2017.04.007. Epub 2017 Apr 23 IF: 6.287

33. Feng Y, Wang Y, Liu H, Liu Z, Mills C, Owzar K, Xie J, Han Y, Qian DC, Hung Rj RJ, Brhane Y, McLaughlin J, Brennan P, Bickeböller H, Rosenberger A, Houlston RS, Caporaso N, Landi MT, Brüske I, Risch A, Ye Y, Wu X, Christiani DC, Amos CI, Wei Q. Novel genetic variants in the P38MAPK pathway gene ZAK and susceptibility to lung cancer. Mol Carcinog. 2018 Feb;57(2):216-224. doi: 10.1002/mc.22748. Epub 2017 Oct 31. IF: 3.851

34. Feng YA, Cho K, Lindstrom S, Kraft P, Cormack J; IGAP Consortium, Colorectal Transdisciplinary Study (CORECT); Discovery, Biology, and Risk of Inherited Variants in Breast Cancer (DRIVE); Elucidating Loci Involved in Prostate Cancer Susceptibility (ELLIPSE); Transdisciplinary Research in Cancer of the Lung (TRICL)C, Liang L, Driver JA. Investigating the genetic relationship between Alzheimer's disease and cancer using GWAS summary statistics. Hum Genet. 2017 Aug 5. doi: 10.1007/s00439-017-1831-6 IF: 4.633

35. Friedrichs S, Manitz J, Burger P, Amos CI, Risch A, Chang-Claude J, Wichmann HE, Kneib T, Bickeböller H, Hofner B. Pathway-Based Kernel Boosting for the Analysis of Genome-Wide Association Studies. Comput Math Methods Med. 2017;2017:6742763. doi: 10.1155/2017/6742763. Epub 2017 Jul 13. IF: 1.545

36. Frost HR, Amos CI. Gene set selection via LASSO penalized regression (SLPR). Nucleic Acids Res. 2017 Jul 7;45(12):e114. doi: 10.1093/nar/gkx291. IF: 10.162

37. Gao Q, Liang WW, Foltz SM, Mutharasu G, Jayasinghe RG, Cao S, Liao WW, Reynolds SM, Wyczalkowski MA, Yao L, Yu L, Sun SQ; Fusion Analysis Working Group; Cancer Genome Atlas Research NetworkA, Chen K, Lazar AJ, Fields RC, Wendl MC, Van Tine BA, Vij R, Chen F, Nykter M, Shmulevich I, Ding L. Driver Fusions and Their Implications in the Development and Treatment of Human Cancers. Cell Rep. 2018 Apr 3;23(1):227-238.e3. doi: 10.1016/j.celrep.2018.03.050. PubMed PMID: 29617662. IF: 8.282

38. Gauderman WJ, Mukherjee B, Aschard H, Hsu L, Lewinger JP, Patel CJ, Witte JS, Amos C, Tai CG, Conti D, Torgerson DG, Lee S, Chatterjee N. Update on the State of the Science for Analytical Methods for Gene-Environment Interactions. Am J Epidemiol. 2017 Oct 1;186(7):762-770. doi: 10.1093/aje/kwx228. IF: 5.230

39. Ge Z, Leighton JS, Wang Y, Peng X, Chen Z, Chen H, Sun Y, Yao F, Li J, Zhang H, Liu J, Shriver CD, Hu H; Cancer Genome Atlas Research NetworkA, Piwnica-Worms H, Ma L, Liang H. Integrated Genomic Analysis of the Ubiquitin Pathway across Cancer Types. Cell Rep. 2018 Apr 3;23(1):213-226.e3. doi:10.1016/j.celrep.2018.03.047. PubMed PMID: 29617661. IF: 8.282

40. Gittleman H, Boscia A, Ostrom QT, Truitt G, Fritz Y, Kruchko C, Barnholtz-Sloan JS. Survivorship in Adults with Malignant Brain and other Central Nervous System Tumor from 2000-2014. Neuro Oncol. 2018 May 29. doi: 10.1093/neuonc/noy090. [Epub ahead of print]

8

PubMed PMID: 29850889. IF: 7.371 41. Gorlova OY, Li Y, Gorlov I, Ying J, Chen WV, Assassi S, Reveille JD, Arnett FC, Zhou X,

Bossini-Castillo L, Lopez-Isac E, Acosta-Herrera M, Gregersen PK, Lee AT, Steen VD, Fessler BJ, Khanna D, Schiopu E, Silver RM, Molitor JA, Furst DE, Kafaja S, Simms RW, Lafyatis RA, Carreira P, Simeon CP, Castellvi I, Beltran E, Ortego N, Amos CI, Martin J, Mayes MD. Gene-level association analysis of systemic sclerosis: A comparison of African-Americans and White populations. PLoS One. 2018 Jan 2;13(1):e0189498. doi: 10.1371/journal.pone.0189498 IF: 2.766

42. Gu F, Zhang H, Hyland PL, Berndt S, Gapstur SM, Wheeler W, Ellipse Consortium T, Amos CI, Bezieau S, Bickeböller H, Brenner H, Brennan P, Chang-Claude J, Conti DV, Doherty JA, Gruber SB, Harrison TA, Hayes RB, Hoffmeister M, Houlston RS, Hung RJ, Jenkins MA, Kraft P, Lawrenson K, McKay J, Markt S, Mucci L, Phelan CM, Qu C, Risch A, Rossing MA, Wichmann HE, Shi J, Schernhammer E, Yu K, Landi MT, Caporaso NE. Inherited variation in circadian rhythm genes and risks of prostate cancer and three other cancer sites in combined cancer consortia. Int J Cancer. 2017 Nov 1;141(9):1794-1802. doi: 10.1002/ijc.30883. Epub 2017 Jul 29. IF: 6.513

43. Hancock DB, Guo Y, Reginsson GW, Gaddis NC, Lutz SM, Sherva R, Loukola A, Minica CC, Markunas CA, Han Y, Young KA, Gudbjartsson DF, Gu F, McNeil DW, Qaiser B, Glasheen C, Olson S, Landi MT, Madden PAF, Farrer LA, Vink J, Saccone NL, Neale MC, Kranzler HR, McKay J, Hung RJ, Amos CI, Marazita ML, Boomsma DI, Baker TB, Gelernter J, Kaprio J, Caporaso NE, Thorgeirsson TE, Hokanson JE, Bierut LJ, Stefansson K, Johnson EO. Genome-wide association study across European and African American ancestries identifies a SNP in DNMT3B contributing to nicotine dependence. Mol Psychiatry. 2017 Oct 3. doi: 10.1038/mp.2017.193 IF: 13.204

44. Hernaez R, Thrift AP. High negative predictive value, low prevalence and spectrum effect: caution in the interpretation. Clin Gastroenterol Hepatol 2017;15(9):1355-1358, PMID: 28501535 IF: 7.896

45. Hoadley KA, Yau C, Hinoue T, Wolf DM, Lazar AJ, Drill E, Shen R, Taylor AM, Cherniack AD, Thorsson V, Akbani R, Bowlby R, Wong CK, Wiznerowicz M, Sanchez-Vega F, Robertson AG, Schneider BG, Lawrence MS, Noushmehr H, Malta TM; Cancer Genome Atlas NetworkA, Stuart JM, Benz CC, Laird PW. Cell-of-Origin Patterns Dominate the Molecular Classification of 10,000 Tumors from 33 Types of Cancer. Cell. 2018 Apr 5;173(2):291-304.e6. doi: 10.1016/j.cell.2018.03.022. PubMed PMID: 29625048. IF: 30.410

46. Huang KL, Mashl RJ, Wu Y, Ritter DI, Wang J, Oh C, Paczkowska M, Reynolds S, Wyczalkowski MA, Oak N, Scott AD, Krassowski M, Cherniack AD, Houlahan KE, Jayasinghe R, Wang LB, Zhou DC, Liu D, Cao S, Kim YW, Koire A, McMichael JF, Hucthagowder V, Kim TB, Hahn A, Wang C, McLellan MD, Al-Mulla F, Johnson KJ; Cancer Genome Atlas Research NetworkA, Lichtarge O, Boutros PC, Raphael B, Lazar AJ, Zhang W, Wendl MC, Govindan R, Jain S, Wheeler D, Kulkarni S, Dipersio JF, Reimand J, Meric-Bernstam F, Chen K, Shmulevich I, Plon SE, Chen F, Ding L. Pathogenic Germline Variants in 10,389 Adult Cancers. Cell. 2018 Apr 5;173(2):355-370.e14. doi: 10.1016/j.cell.2018.03.039. PubMed PMID: 29625052. IF: 30.410

47. Hur C, Zhan T, Thrift AP, Vaughan TL, Feuer EJ. Lorenz curves and gini coefficient analyses indicate inefficiencies in esophageal adenocarcinoma screening. Clin Gastroenterol Hepatol. 9 May 2018 doi: 10.1016/j.cgh.2018.05.002. [Epub ahead of print], PMID: 29753084 IF: 7.896

9

48. Jacobs DI, Liu Y, Gabrusiewicz K, Tsavachidis S, Armstrong GN, Zhou R, Wei J, Ivan C, Calin G, Molinaro AM, Rice T, Bracci PM, Hansen HM, Wiencke JK, Wrensch MR, Heimberger AB, Bondy ML. Germline polymorphisms in myeloid-associated genes are not associated with survival in glioma patients. J Neurooncol. 2018 Jan;136(1):33-39. doi: 10.1007/s11060-017-2622-6. Epub 2017 Sep 30. IF: 3.060

49. Jayasinghe RG, Cao S, Gao Q, Wendl MC, Vo NS, Reynolds SM, Zhao Y, Climente-González H, Chai S, Wang F, Varghese R, Huang M, Liang WW, Wyczalkowski MA, Sengupta S, Li Z, Payne SH, Fenyö D, Miner JH, Walter MJ; Cancer Genome Atlas Research NetworkA, Vincent B, Eyras E, Chen K, Shmulevich I, Chen F, Ding L. Systematic Analysis of Splice-Site-Creating Mutations in Cancer. Cell Rep. 2018 Apr 3;23(1):270-281.e3. doi: 0.1016/j.celrep.2018.03.052. PubMed PMID: 29617666. IF: 8.282

50. Ji X, Niu X, Qian J, Martucci V, Pendergrass SA, Gorlov IP, Amos CI, Denny JC, Massion PP, Aldrich MC. A Phenome-Wide Association Study Uncovers a Role for Autoimmunity in the Development of Chronic Obstructive Pulmonary Disease.Am J Respir Cell Mol Biol. 2018 Jun;58(6):777-779. doi: 10.1165/rcmb.2017-0409LE. PMID: 29856256 IF: 3.790

51. Kaur M, Singapura P, Kalakota N, Cruz G, Shukla R, Ahsan S, Tansel A, Thrift AP, El-Serag HB. Factors that contribute to indeterminate results from the QuantiFERON-TB Gold in-tube test in patients with inflammatory bowel disease. Clin Gastroenterol Hepatol. 23 Nov 2017. doi: 10.1016/j.cgh.2017.11.038. [Epub ahead of print], PMID: 29175527 IF: 7.896

52. Khanna V, Achey RL, Ostrom QT, Block-Beach H, Kruchko C, Barnholtz-Sloan JS, de Blank PM. Incidence and Survival Trends for Medulloblastomas in the United States from 2001 to 2013. J Neurooncol. 2017 Aug 21. doi: 10.1007/s11060-017-2594-6. [Epub ahead of print] PubMed PMID: 28828582. IF: 3.060

53. Kinnersley B, Houlston RS, Bondy ML. Genome-Wide Association Studies in Glioma. Cancer Epidemiol Biomarkers Prev. 2018 Apr;27(4):418-428. doi: 10.1158/1055-9965.EPI-17-1080. Epub 2018 Jan 30. PMID: 29382702 IF: 4.125

54. Knijnenburg TA, Wang L, Zimmermann MT, Chambwe N, Gao GF, Cherniack AD, Fan H, Shen H, Way GP, Greene CS, Liu Y, Akbani R, Feng B, Donehower LA, Miller C, Shen Y, Karimi M, Chen H, Kim P, Jia P, Shinbrot E, Zhang S, Liu J, Hu H, Bailey MH, Yau C, Wolf D, Zhao Z, Weinstein JN, Li L, Ding L, Mills GB, Laird PW, Wheeler DA, Shmulevich I; Cancer Genome Atlas Research NetworkA, Monnat RJ Jr., Xiao Y, Wang C. Genomic and Molecular Landscape of DNA Damage Repair Deficiency across The Cancer Genome Atlas. Cell Rep. 2018 Apr 3;23(1):239-254.e6. doi: 10.1016/j.celrep.2018.03.076. PubMed PMID: 29617664. IF: 3.060

55. Kruchko C, Ostrom QT, Gittleman H, Barnholtz-Sloan JS. The CBTRUS Story: Providing Accurate Population-based Statistics on Brain and Other Central Nervous System Tumors for Everyone. Neuro Oncol. 2018 Feb;20(3):295-298. doi: 10.1093/neuonc/noy002 IF: 7.371

56. Kumar RG, Juengst SB, Wang Z, Dams-O'Connor K, Dikmen SS, O'Neil-Pirozzi TM, Dahdah MN, Hammond FM, Felix ER, Arenth PM, Wagner AK. Epidemiology of Comorbid Conditions Among Adults 50 Years and Older With Traumatic Brain Injury. J Head Trauma Rehabil 2017. IF: 3.406

57. Kumar RG, Wang Z (co-first author with Kumar RG), Kesinger MR, Newman M, Huynh TT, Niemeier JP, Sperry JL, Wagner AK. Probabilistic Matching of Deidentified Data From a Trauma Registry and a Traumatic Brain Injury Model System Center: A Follow-up Validation Study. American journal of physical medicine & rehabilitation 2018;97: 236-41.

10

IF: 1.843 58. Kunzmann AT, Thrift AP, Cardwell CR, Lagergren J, Xie S, Johnston BT, Anderson LA,

Busby J, McMenamin UC, Spence AD, Coleman HG. Model for identifying individuals at risk for esophageal adenocarcinoma. Clin Gastroenterol Hepatol. 17 Mar 2018 doi: 10.1016/j.cgh.2018.03.014. [Epub ahead of print], PMID: 29559360 IF: 7.896

59. Li B, Wang Y, Xu Y, Liu H, Bloomer W, Zhu D, Amos CI, Fang S, Lee JE, Li X, Han J, Wei Q. Genetic variants in RORA and DNMT1 associated with cutaneous melanoma survival. Int J Cancer. 2018 Jan 4. doi: 10.1002/ijc.31243. IF: 6.513

60. Li H, Wang Y, Liu H, Shi Q, Li H, Wu W, Zhu D, Amos CI, Fang S, Lee JE, Li Y, Han J, Wei Q. Genetic variants of PDGF signaling pathway genes predict cutaneous melanoma survival. Oncotarget. 2017 Aug 14;8(43):74595-74606. doi: 10.18632/oncotarget.20245. eCollection 2017 Sep 26 IF: 5.168

61. Liao P, Ostrom QT, Stetson L, Barnholtz-Sloan JS. Models of Epigenetic Age Capture Patterns of DNA Methylation in Glioma Associated with Molecular Subtype, Survival, and Recurrence. Neuro Oncol. 2018 Feb 8. doi: 10.1093/neuonc/noy003. [Epub ahead of print] PubMed PMID: 29432558. IF: 7.371

62. Liu J, Lichtenberg T, Hoadley KA, Poisson LM, Lazar AJ, Cherniack AD, Kovatich AJ, Benz CC, Levine DA, Lee AV, Omberg L, Wolf DM, Shriver CD, Thorsson V; Cancer Genome Atlas Research NetworkA, Hu H. An Integrated TCGA Pan-Cancer Clinical Data Resource to Drive High-Quality Survival Outcome Analytics. Cell. 2018 Apr 5;173(2):400-416.e11. doi: 10.1016/j.cell.2018.02.052. PubMed PMID: 29625055. IF: 30.410

63. Liu Y, Lusk CM, Cho MH, Silverman EK, Qiao D, Zhang R, Scheurer ME, Kheradmand F, Wheeler DA, Tsavachidis S, Armstrong G, Zhu D, Wistuba II, Chow CB, Behrens C, Pikielny CW, Neslund-Dudas C, Pinney SM, Anderson M, Kupert E, Bailey-Wilson J, Gaba C, Mandal D, You M, de Andrade M, Yang P, Field JK, Liloglou T, Davies M, Lissowska J, Swiatkowska B, Zaridze D, Mukeriya A, Janout V, Holcatova I, Mates D, Milosavljevic S, Scelo G, Brennan P, McKay J, Liu G, Hung RJ; COPDGene Investigators, Christiani DC, Schwartz AG, Amos CI, Spitz MR. Rare Variants in Known Susceptibility Loci and Their Contribution to Risk of Lung Cancer. J Thorac Oncol. 2018 Jul 4. pii: S1556-0864(18)30767-6. doi: 10.1016/j.jtho.2018.06.016. PMID: 29981437 IF: 10.336

64. Liu Y, Sethi NS, Hinoue T, Schneider BG, Cherniack AD, Sanchez-Vega F, Seoane JA, Farshidfar F, Bowlby R, Islam M, Kim J, Chatila W, Akbani R, Kanchi RS, Rabkin CS, Willis JE, Wang KK, McCall SJ, Mishra L, Ojesina AI, Bullman S, Pedamallu CS, Lazar AJ, Sakai R; Cancer Genome Atlas Research NetworkA, Thorsson V, Bass AJ, Laird PW. Comparative Molecular Analysis of Gastrointestinal Adenocarcinomas. Cancer Cell. 2018 Apr 9;33(4):721-735.e8. doi: 10.1016/j.ccell.2018.03.010. Epub 2018 Apr 2. PubMed PMID: 29622466. IF: 27.407

65. Lohavanichbutr P, Sakoda LC, Amos CI, Arnold SM, Christiani DC, Davies MPA, Field JK, Haura EB, Hung RJ, Kohno T, Landi MT, Liu G, Liu Y, Marcus MW, O'Kane GM, Schabath MB, Shiraishi K, Slone SA, Tardon A, Yang P, Yoshida K, Zhang R, Zong X, Goodman GG, Weiss NS, Chen C. Common TDP1 polymorphisms in relation to survival among small cell lung cancer patients: a multicenter study from the International Lung Cancer Consortium. Clin Cancer Res. 2017 Oct 3. pii: clincanres.1401.2017. doi: 10.1158/1078-0432.CCR-17-1401. IF: 10.199

66. Malta TM, Sokolov A, Gentles AJ, Burzykowski T, Poisson L, Weinstein JN, Kamińska B, Huelsken J, Omberg L, Gevaert O, Colaprico A, Czerwińska P, Mazurek S, Mishra L, Heyn H, Krasnitz A, Godwin AK, Lazar AJ; Cancer Genome Atlas Research NetworkA, Stuart

11

JM, Hoadley KA, Laird PW, Noushmehr H, Wiznerowicz M. Machine Learning Identifies Stemness Features Associated with Oncogenic Dedifferentiation. Cell. 2018 Apr 5;173(2):338-354.e15. doi: 10.1016/j.cell.2018.03.034. PubMed PMID: 29625051; PubMed Central PMCID: PMC5902191. IF: 30.140

67. McAllister K, Mechanic LE, Amos C, Aschard H, Blair IA, Chatterjee N, Conti D, Gauderman WJ, Hsu L, Hutter CM, Jankowska MM, Kerr J, Kraft P, Montgomery SB, Mukherjee B, Papanicolaou GJ, Patel CJ, Ritchie MD, Ritz BR, Thomas DC, Wei P, Witte JS. Current Challenges and New Opportunities for Gene-Environment Interaction Studies of Complex Diseases. Am J Epidemiol. 2017 Oct 1;186(7):753-761. doi: 10.1093/aje/kwx227. IF: 5.230

68. McKay JD, Hung RJ, Han Y, Zong X, Carreras-Torres R, Christiani DC, Caporaso NE, Johansson M, Xiao X, Li Y, Byun J, Dunning A, Pooley KA, Qian DC, Ji X, Liu G, Timofeeva MN, Bojesen SE, Wu X, Le Marchand L, Albanes D, Bickeböller H, Aldrich MC, Bush WS, Tardon A, Rennert G, Teare MD, Field JK, Kiemeney LA, Lazarus P, Haugen A, Lam S, Schabath MB, Andrew AS, Shen H, Hong YC, Yuan JM, Bertazzi PA, Pesatori AC, Ye Y, Diao N, Su L, Zhang R, Brhane Y, Leighl N, Johansen JS, Mellemgaard A, Saliba W, Haiman CA, Wilkens LR, Fernandez-Somoano A, Fernandez-Tardon G, van der Heijden HFM, Kim JH, Dai J, Hu Z, Davies MPA, Marcus MW, Brunnström H, Manjer J, Melander O, Muller DC, Overvad K, Trichopoulou A, Tumino R, Doherty JA, Barnett MP, Chen C, Goodman GE, Cox A, Taylor F, Woll P, Brüske I, Wichmann HE, Manz J, Muley TR, Risch A, Rosenberger A, Grankvist K, Johansson M, Shepherd FA, Tsao MS, Arnold SM, Haura EB, Bolca C, Holcatova I, Janout V, Kontic M, Lissowska J, Mukeria A, Ognjanovic S, Orlowski TM, Scelo G, Swiatkowska B, Zaridze D, Bakke P, Skaug V, Zienolddiny S, Duell EJ, Butler LM, Koh WP, Gao YT, Houlston RS, McLaughlin J, Stevens VL, Joubert P, Lamontagne M, Nickle DC, Obeidat M, Timens W, Zhu B, Song L, Kachuri L, Artigas MS, Tobin MD, Wain LV; SpiroMeta Consortium, Rafnar T, Thorgeirsson TE, Reginsson GW, Stefansson K, Hancock DB, Bierut LJ, Spitz MR, Gaddis NC, Lutz SM, Gu F, Johnson EO, Kamal A, Pikielny C, Zhu D, Lindströem S, Jiang X, Tyndale RF, Chenevix-Trench G, Beesley J, Bossé Y, Chanock S, Brennan P, Landi MT, Amos CI. Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes. Nat Genet. 2017 Jul;49(7):1126-1132. doi: 10.1038/ng.3892. Epub 2017 Jun 12. PMID: 28604730 IF: 27.959

69. McNamara C, Abbott SE, Bandera EV, Qin B, Peres LC, Camacho F, Moorman PG, Alberg AJ, Barnholtz-Sloan JS, Bondy M, Cote ML, Funkhouser E, Peters ES, Schwartz AG, Schildkraut JM, Terry P. Tubal ligation and ovarian cancer risk in African American women. Cancer Causes Control. 2017 Oct;28(10):1033-1041. doi: 10.1007/s10552-017-0943-6. Epub 2017 Sep 4. PMID: 28871344 IF: 2.735

70. Mechanic LE, Lindström S, Daily KM, Sieberts SK, Amos CI, Chen HS, Cox NJ, Dathe M, Feuer EJ, Guertin MJ, Hoffman J, Liu Y, Moore JH, Myers CL, Ritchie MD, Schildkraut J, Schumacher F, Witte JS, Wang W, Williams SM; U4C Challenge Participants; U4C Challenge Data Contributors, Gillanders EM. Up For A Challenge (U4C): Stimulating innovation in breast cancer genetic epidemiology. PLoS Genet. 2017 Sep 28;13(9):e1006945. doi: 10.1371/journal.pgen.1006945. eCollection 2017 Sep. IF: 6.10

71. Mendez JS, Ostrom QT, Gittleman H, Kruchko C, DeAngelis LM, Barnholtz-Sloan JS, Grommes C. The Elderly Left Behind - Changes in Survival Trends of Primary Central Nervous System Lymphoma Over The Past Four Decades. Neuro Oncol. 2017 Oct 3. doi: 10.1093/neuonc/nox187. [Epub ahead of print] PubMed PMID: 29036697. IF: 7.371

12

72. Michailidou K, Lindström S, Dennis J, Beesley J, Hui S, Kar S, Lemaçon A, Soucy P, Glubb D, Rostamianfar A, Bolla MK, Wang Q, Tyrer J, Dicks E, Lee A, Wang Z, Allen J, Keeman R, Eilber U, French JD, Qing Chen X, Fachal L, McCue K, McCart Reed AE, Ghoussaini M, Carroll JS, Jiang X, Finucane H, Adams M, Adank MA, Ahsan H, Aittomäki K, Anton-Culver H, Antonenkova NN, Arndt V, Aronson KJ, Arun B, Auer PL, Bacot F, Barrdahl M, Baynes C, Beckmann MW, Behrens S, Benitez J, Bermisheva M, Bernstein L, Blomqvist C, Bogdanova NV, Bojesen SE, Bonanni B, Børresen-Dale AL, Brand JS, Brauch H, Brennan P, Brenner H, Brinton L, Broberg P, Brock IW, Broeks A, Brooks-Wilson A, Brucker SY, Brüning T, Burwinkel B, Butterbach K, Cai Q, Cai H, Caldés T, Canzian F, Carracedo A, Carter BD, Castelao JE, Chan TL, David Cheng TY, Seng Chia K, Choi JY, Christiansen H, Clarke CL; NBCS Collaborators, Collée M, Conroy DM, Cordina-Duverger E, Cornelissen S, Cox DG, Cox A, Cross SS, Cunningham JM, Czene K, Daly MB, Devilee P, Doheny KF, Dörk T, Dos-Santos-Silva I, Dumont M, Durcan L, Dwek M, Eccles DM, Ekici AB, Eliassen AH, Ellberg C, Elvira M, Engel C, Eriksson M, Fasching PA, Figueroa J, Flesch-Janys D, Fletcher O, Flyger H, Fritschi L, Gaborieau V, Gabrielson M, Gago-Dominguez M, Gao YT, Gapstur SM, García-Sáenz JA, Gaudet MM, Georgoulias V, Giles GG, Glendon G, Goldberg MS, Goldgar DE, González-Neira A, Grenaker Alnæs GI, Grip M, Gronwald J, Grundy A, Guénel P, Haeberle L, Hahnen E, Haiman CA, Håkansson N, Hamann U, Hamel N, Hankinson S, Harrington P, Hart SN, Hartikainen JM, Hartman M, Hein A, Heyworth J, Hicks B, Hillemanns P, Ho DN, Hollestelle A, Hooning MJ, Hoover RN, Hopper JL, Hou MF, Hsiung CN, Huang G, Humphreys K, Ishiguro J, Ito H, Iwasaki M, Iwata H, Jakubowska A, Janni W, John EM, Johnson N, Jones K, Jones M, Jukkola-Vuorinen A, Kaaks R, Kabisch M, Kaczmarek K, Kang D, Kasuga Y, Kerin MJ, Khan S, Khusnutdinova E, Kiiski JI, Kim SW, Knight JA, Kosma VM, Kristensen VN, Krüger U, Kwong A, Lambrechts D, Le Marchand L, Lee E, Lee MH, Lee JW, Neng Lee C, Lejbkowicz F, Li J, Lilyquist J, Lindblom A, Lissowska J, Lo WY, Loibl S, Long J, Lophatananon A, Lubinski J, Luccarini C, Lux MP, Ma ESK, MacInnis RJ, Maishman T, Makalic E, Malone KE, Kostovska IM, Mannermaa A, Manoukian S, Manson JE, Margolin S, Mariapun S, Martinez ME, Matsuo K, Mavroudis D, McKay J, McLean C, Meijers-Heijboer H, Meindl A, Menéndez P, Menon U, Meyer J, Miao H, Miller N, Taib NAM, Muir K, Mulligan AM, Mulot C, Neuhausen SL, Nevanlinna H, Neven P, Nielsen SF, Noh DY, Nordestgaard BG, Norman A, Olopade OI, Olson JE, Olsson H, Olswold C, Orr N, Pankratz VS, Park SK, Park-Simon TW, Lloyd R, Perez JIA, Peterlongo P, Peto J, Phillips KA, Pinchev M, Plaseska-Karanfilska D, Prentice R, Presneau N, Prokofyeva D, Pugh E, Pylkäs K, Rack B, Radice P, Rahman N, Rennert G, Rennert HS, Rhenius V, Romero A, Romm J, Ruddy KJ, Rüdiger T, Rudolph A, Ruebner M, Rutgers EJT, Saloustros E, Sandler DP, Sangrajrang S, Sawyer EJ, Schmidt DF, Schmutzler RK, Schneeweiss A, Schoemaker MJ, Schumacher F, Schürmann P, Scott RJ, Scott C, Seal S, Seynaeve C, Shah M, Sharma P, Shen CY, Sheng G, Sherman ME, Shrubsole MJ, Shu XO, Smeets A, Sohn C, Southey MC, Spinelli JJ, Stegmaier C, Stewart-Brown S, Stone J, Stram DO, Surowy H, Swerdlow A, Tamimi R, Taylor JA, Tengström M, Teo SH, Beth Terry M, Tessier DC, Thanasitthichai S, Thöne K, Tollenaar RAEM, Tomlinson I, Tong L, Torres D, Truong T, Tseng CC, Tsugane S, Ulmer HU, Ursin G, Untch M, Vachon C, van Asperen CJ, Van Den Berg D, van den Ouweland AMW, van der Kolk L, van der Luijt RB, Vincent D, Vollenweider J, Waisfisz Q, Wang-Gohrke S, Weinberg CR, Wendt C, Whittemore AS, Wildiers H, Willett W, Winqvist R, Wolk A, Wu AH, Xia L, Yamaji T, Yang XR, Har Yip C, Yoo KY, Yu JC, Zheng W, Zheng Y, Zhu B, Ziogas A, Ziv E; ABCTB

13

Investigators; ConFab/AOCS Investigators, Lakhani SR, Antoniou AC, Droit A, Andrulis IL, Amos CI, Couch FJ, Pharoah PDP, Chang-Claude J, Hall P, Hunter DJ, Milne RL, García-Closas M, Schmidt MK, Chanock SJ, Dunning AM, Edwards SL, Bader GD, Chenevix-Trench G, Simard J, Kraft P, Easton DF. Association analysis identifies 65 new breast cancer risk loci. Nature. 2017 Nov 2;551(7678):92-94. doi: 10.1038/nature24284. IF: 40.137

73. Mills AM, Peres LC, Meiss A, Ring KL, Modesitt SC, Abbott SE, Alberg AJ, Bandera EV, Barnholtz-Sloan J, Bondy ML, Cote ML, Funkhouser E, Moorman PG, Peters ES, Schwartz AG, Terry PD, Wallace K, Schildkraut JM. Targetable Immune Regulatory Molecule Expression in High-Grade Serous Ovarian Carcinomas in African American Women: A Study of PD-L1 and IDO in 112 Cases From the African American Cancer Epidemiology Study (AACES). Int J Gynecol Pathol. 2018 Feb 26. doi: 10.1097/PGP.0000000000000494. [Epub ahead of print] PMID 29485423 IF: 1.628

74. Milne RL, Kuchenbaecker KB, Michailidou K, Beesley J, Kar S, Lindström S, Hui S, Lemaçon A, Soucy P, Dennis J, Jiang X, Rostamianfar A, Finucane H, Bolla MK, McGuffog L, Wang Q, Aalfs CM; ABCTB Investigators, Adams M, Adlard J, Agata S, Ahmed S, Ahsan H, Aittomäki K, Al-Ejeh F, Allen J, Ambrosone CB, Amos CI, Andrulis IL, Anton-Culver H, Antonenkova NN, Arndt V, Arnold N, Aronson KJ, Auber B, Auer PL, Ausems MGEM, Azzollini J, Bacot F, Balmaña J, Barile M, Barjhoux L, Barkardottir RB, Barrdahl M, Barnes D, Barrowdale D, Baynes C, Beckmann MW, Benitez J, Bermisheva M, Bernstein L, Bignon YJ, Blazer KR, Blok MJ, Blomqvist C, Blot W, Bobolis K, Boeckx B, Bogdanova NV, Bojesen A, Bojesen SE, Bonanni B, Børresen-Dale AL, Bozsik A, Bradbury AR, Brand JS, Brauch H, Brenner H, Bressac-de Paillerets B, Brewer C, Brinton L, Broberg P, Brooks-Wilson A, Brunet J, Brüning T, Burwinkel B, Buys SS, Byun J, Cai Q, Caldés T, Caligo MA, Campbell I, Canzian F, Caron O, Carracedo A, Carter BD, Castelao JE, Castera L, Caux-Moncoutier V, Chan SB, Chang-Claude J, Chanock SJ, Chen X, Cheng TD, Chiquette J, Christiansen H, Claes KBM, Clarke CL, Conner T, Conroy DM, Cook J, Cordina-Duverger E, Cornelissen S, Coupier I, Cox A, Cox DG, Cross SS, Cuk K, Cunningham JM, Czene K, Daly MB, Damiola F, Darabi H, Davidson R, De Leeneer K, Devilee P, Dicks E, Diez O, Ding YC, Ditsch N, Doheny KF, Domchek SM, Dorfling CM, Dörk T, Dos-Santos-Silva I, Dubois S, Dugué PA, Dumont M, Dunning AM, Durcan L, Dwek M, Dworniczak B, Eccles D, Eeles R, Ehrencrona H, Eilber U, Ejlertsen B, Ekici AB, Eliassen AH; EMBRACE, Engel C, Eriksson M, Fachal L, Faivre L, Fasching PA, Faust U, Figueroa J, Flesch-Janys D, Fletcher O, Flyger H, Foulkes WD, Friedman E, Fritschi L, Frost D, Gabrielson M, Gaddam P, Gammon MD, Ganz PA, Gapstur SM, Garber J, Garcia-Barberan V, García-Sáenz JA, Gaudet MM, Gauthier-Villars M, Gehrig A; GEMO Study Collaborators, Georgoulias V, Gerdes AM, Giles GG, Glendon G, Godwin AK, Goldberg MS, Goldgar DE, González-Neira A, Goodfellow P, Greene MH, Alnæs GIG, Grip M, Gronwald J, Grundy A, Gschwantler-Kaulich D, Guénel P, Guo Q, Haeberle L, Hahnen E, Haiman CA, Håkansson N, Hallberg E, Hamann U, Hamel N, Hankinson S, Hansen TVO, Harrington P, Hart SN, Hartikainen JM, Healey CS; HEBON, Hein A, Helbig S, Henderson A, Heyworth J, Hicks B, Hillemanns P, Hodgson S, Hogervorst FB, Hollestelle A, Hooning MJ, Hoover B, Hopper JL, Hu C, Huang G, Hulick PJ, Humphreys K, Hunter DJ, Imyanitov EN, Isaacs C, Iwasaki M, Izatt L, Jakubowska A, James P, Janavicius R, Janni W, Jensen UB, John EM, Johnson N, Jones K, Jones M, Jukkola-Vuorinen A, Kaaks R, Kabisch M, Kaczmarek K, Kang D, Kast K; kConFab/AOCS Investigators, Keeman R, Kerin MJ, Kets CM, Keupers M, Khan S, Khusnutdinova E, Kiiski JI, Kim SW, Knight JA, Konstantopoulou I, Kosma VM, Kristensen

14

VN, Kruse TA, Kwong A, Lænkholm AV, Laitman Y, Lalloo F, Lambrechts D, Landsman K, Lasset C, Lazaro C, Le Marchand L, Lecarpentier J, Lee A, Lee E, Lee JW, Lee MH, Lejbkowicz F, Lesueur F, Li J, Lilyquist J, Lincoln A, Lindblom A, Lissowska J, Lo WY, Loibl S, Long J, Loud JT, Lubinski J, Luccarini C, Lush M, MacInnis RJ, Maishman T, Makalic E, Kostovska IM, Malone KE, Manoukian S, Manson JE, Margolin S, Martens JWM, Martinez ME, Matsuo K, Mavroudis D, Mazoyer S, McLean C, Meijers-Heijboer H, Menéndez P, Meyer J, Miao H, Miller A, Miller N, Mitchell G, Montagna M, Muir K, Mulligan AM, Mulot C, Nadesan S, Nathanson KL; NBSC Collaborators, Neuhausen SL, Nevanlinna H, Nevelsteen I, Niederacher D, Nielsen SF, Nordestgaard BG, Norman A, Nussbaum RL, Olah E, Olopade OI, Olson JE, Olswold C, Ong KR, Oosterwijk JC, Orr N, Osorio A, Pankratz VS, Papi L, Park-Simon TW, Paulsson-Karlsson Y, Lloyd R, Pedersen IS, Peissel B, Peixoto A, Perez JIA, Peterlongo P, Peto J, Pfeiler G, Phelan CM, Pinchev M, Plaseska-Karanfilska D, Poppe B, Porteous ME, Prentice R, Presneau N, Prokofieva D, Pugh E, Pujana MA, Pylkäs K, Rack B, Radice P, Rahman N, Rantala J, Rappaport-Fuerhauser C, Rennert G, Rennert HS, Rhenius V, Rhiem K, Richardson A, Rodriguez GC, Romero A, Romm J, Rookus MA, Rudolph A, Ruediger T, Saloustros E, Sanders J, Sandler DP, Sangrajrang S, Sawyer EJ, Schmidt DF, Schoemaker MJ, Schumacher F, Schürmann P, Schwentner L, Scott C, Scott RJ, Seal S, Senter L, Seynaeve C, Shah M, Sharma P, Shen CY, Sheng X, Shimelis H, Shrubsole MJ, Shu XO, Side LE, Singer CF, Sohn C, Southey MC, Spinelli JJ, Spurdle AB, Stegmaier C, Stoppa-Lyonnet D, Sukiennicki G, Surowy H, Sutter C, Swerdlow A, Szabo CI, Tamimi RM, Tan YY, Taylor JA, Tejada MI, Tengström M, Teo SH, Terry MB, Tessier DC, Teulé A, Thöne K, Thull DL, Tibiletti MG, Tihomirova L, Tischkowitz M, Toland AE, Tollenaar RAEM, Tomlinson I, Tong L, Torres D, Tranchant M, Truong T, Tucker K, Tung N, Tyrer J, Ulmer HU, Vachon C, van Asperen CJ, Van Den Berg D, van den Ouweland AMW, van Rensburg EJ, Varesco L, Varon-Mateeva R, Vega A, Viel A, Vijai J, Vincent D, Vollenweider J, Walker L, Wang Z, Wang-Gohrke S, Wappenschmidt B, Weinberg CR, Weitzel JN, Wendt C, Wesseling J, Whittemore AS, Wijnen JT, Willett W, Winqvist R, Wolk A, Wu AH, Xia L, Yang XR, Yannoukakos D, Zaffaroni D, Zheng W, Zhu B, Ziogas A, Ziv E, Zorn KK, Gago-Dominguez M, Mannermaa A, Olsson H, Teixeira MR, Stone J, Offit K, Ottini L, Park SK, Thomassen M, Hall P, Meindl A, Schmutzler RK, Droit A, Bader GD, Pharoah PDP, Couch FJ, Easton DF, Kraft P, Chenevix-Trench G, García-Closas M, Schmidt MK, Antoniou AC, Simard J. Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer. Nat Genet. 2017 Dec;49(12):1767-1778. doi: 10.1038/ng.3785 IF: 27.959

75. Miraflor AP, de Abreu FB, Peterson JD, Turner SA, Amos CI, Tsongalis GJ, Yan S. Somatic mutation analysis in melanoma using targeted next generation sequencing. Exp Mol Pathol. 2017 Aug 16;103(2):172-177. doi: 10.1016/j.yexmp.2017.08.006. IF: 2.566

76. Mostovenko E, Liu Y, Amirian ES, Tsavachidis S, Armstrong GN, Bondy ML, Nilsson CL. Combined Proteomic-Molecular Epidemiology Approach to Identify Precision Targets in Brain Cancer. ACS Chem Neurosci. 2017 Jul 11. doi: 10.1021/acschemneuro.7b00165. [Epub ahead of print] PMID: 28657708 IF: 4.211

77. Musolf AM, Simpson CL, de Andrade M, Mandal D, Gaba C, Yang P, Li Y, You M, Kupert EY, Anderson MW, Schwartz AG, Pinney SM, Amos CI, Bailey-Wilson JE. Parametric Linkage Analysis Identifies Five Novel Genome-Wide Significant Loci for Familial Lung Cancer. Hum Hered. 2016;82(1-2):64-74. doi: 10.1159/000479028. Epub 2017 Aug 18. IF: 0.542

78. Nguyen T, Khan A, Liu Y, El-Serag HB, Thrift AP. The association between statin use

15

after diagnosis and mortality risk in patients with esophageal cancer: a retrospective cohort study of United States Veterans. Am J Gastroenterol. 27 June 2018 doi: 10.1038/s41395-018-0169-6. [Epub ahead of print], PMID: 29946180 IF: 10.383

79. Nguyen T, Thrift AP, Yu X, Duan Z, El-Serag HB. The annual risk of esophageal adenocarcinoma does not decrease over time in patients with Barrett’s esophagus. Am J Gastroenterol 2017;112(7):1049-1055, PMID: 28244499 IF: 10.383

80. Ostrom QT*, Cote DJ*, Ascha M, Kruchko C, Barnholtz-Sloan JS. Adult Glioma Incidence and Survival by Race or Ethnicity in the United States From 2000 to 2014. JAMA Oncol. 2018 Jun 21:e181789. doi: 10.1001/jamaoncol.2018.1789. [Epub ahead of print] PubMed PMID: 29931168. (*Contributed equally to manuscript) IF: 20.871

81. Ostrom QT, Gittleman H, Liao P, Vecchione-Koval T, Wolinsky Y, Kruchko C, Barnholtz-Sloan JS. CBTRUS Statistical Report: Primary Brain and Other Central Nervous System Tumors Diagnosed in the United States in 2010-2014. Neuro Oncol. 2017 Nov 6;19(suppl_5):v1-v88. doi: 10.1093/neuonc/nox158. PubMed PMID: 29117289; PubMed Central PMCID: PMC5693142. IF: 7.371

82. Ostrom QT, Kinnersley B, Wrensch MR, Eckel-Passow JE, Armstrong G, Rice T, Chen Y, Wiencke JK, McCoy LS, Hansen HM, Amos CI, Bernstein JL, Claus EB, Il'yasova D, Johansen C, Lachance DH, Lai RK, Merrell RT, Olson SH, Sadetzki S, Schildkraut JM, Shete S, Rubin JB, Lathia JD, Berens ME, Andersson U, Rajaraman P, Chanock SJ, Linet MS, Wang Z, Yeager M; GliomaScan consortium, Houlston RS, Jenkins RB, Melin B, Bondy ML, Barnholtz-Sloan JS. Sex-Specific Glioma Genome-Wide Association Study Identifies New Risk Locus at 3p21.31 in Females, and Finds Sex-Differences In Risk At 8q24.21. Sci Rep. 2018 May 9;8(1):7352. doi: 10.1038/s41598-018-24580-z. PubMed PMID: 29743610; PubMed Central PMCID: PMC5943590. IF: 4.122

83. Ostrom QT, Rubin JB, Lathia JD, Berens ME, Barnholtz-Sloan JS. Females Have the Survival Advantage in Glioblastoma. Neuro Oncol. 2018. doi: 10.1093/neuonc/noy002. IF: 7.371

84. Pande M, Joon A, Brewster AM, Chen WV, Hopper JL, Eng C, Shete S, Casey G, Schumacher F, Lin Y, Harrison TA, White E, Ahsan H, Andrulis IL, Whittemore AS, John EM, Ko Win A, Makalic E, Schmidt DF, Kapuscinski MK, Ochs-Balcom HM, Gallinger S, Jenkins MA, Newcomb PA, Lindor NM, Peters U, Amos CI, Lynch PM. Genetic susceptibility markers for a breast-colorectal cancer phenotype: Exploratory results from genome-wide association studies. PLoS One. 2018 Apr 26;13(4):e0196245. doi: 10.1371/journal.pone.0196245. IF: 2.766

85. Patel CJ, Kerr J, Thomas DC, Mukherjee B, Ritz B, Chatterjee N, Jankowska M, Madan J, Karagas MR, McAllister KA, Mechanic LE, Fallin MD, Ladd-Acosta C, Blair IA, Teitelbaum SL, Amos CI. Opportunities and Challenges for Environmental Exposure Assessment in Population-Based Studies. Cancer Epidemiol Biomarkers Prev. 2017 Sep;26(9):1370-1380. doi: 10.1158/1055-9965.EPI-17-0459. Epub 2017 Jul 14. IF: 4.125

86. Peng X, Chen Z, Farshidfar F, Xu X, Lorenzi PL, Wang Y, Cheng F, Tan L, Mojumdar K, Du D, Ge Z, Li J, Thomas GV, Birsoy K, Liu L, Zhang H, Zhao Z, Marchand C, Weinstein JN; Cancer Genome Atlas Research NetworkA, Bathe OF, Liang H. Molecular Characterization and Clinical Relevance of Metabolic Expression Subtypes in Human Cancers. Cell Rep. 2018 Apr 3;23(1):255-269.e4. doi: 10.1016/j.celrep.2018.03.077. PubMed PMID: 29617665. IF: 8.282

87. Peres LC, Alberg AJ, Bandera EV, Barnholtz-Sloan J, Bondy M, Cote ML, Funkhouser E, Moorman PG, Peters ES, Schwartz AG, Terry PD, Abbott SE, Camacho F, Wang F,

16

Schildkraut JM. Premenopausal Hysterectomy and Risk of Ovarian Cancer in African-American Women. Am J Epidemiol. 2017 Jul 1;186(1):46-53. doi: 10.1093/aje/kwx055. PMID: 28444120 IF: 5.230

88. Peres LC, Risch H, Terry KL, Webb PM, Goodman MT, Wu AH, Alberg AJ, Bandera EV, Barnholtz-Sloan J, Bondy ML, Cote ML, Funkhouser E, Moorman PG, Peters ES, Schwartz AG, Terry PD, Manichaikul A, Abbott SE, Camacho F, Jordan SJ, Nagle CM; Australian Ovarian Cancer Study Group, Rossing MA, Doherty JA, Modugno F, Moysich K, Ness R, Berchuck A, Cook L, Le N, Brooks-Wilson A, Sieh W, Whittemore A, McGuire V, Rothstein J, Anton-Culver H, Ziogas A, Pearce CL, Tseng C, Pike M, Schildkraut JM; African American Cancer Epidemiology Study and the Ovarian Cancer Association Consortium. Racial/ethnic differences in the epidemiology of ovarian cancer: a pooled analysis of 12 case-control studies. Int J Epidemiol. 2018 Apr 1;47(2):460-472. doi: 10.1093/ije/dyx252. PMID 29211900 IF: 7.522

89. Qian DC, Molfese DL, Jin JL, Titus AJ, He Y, Li Y, Vaissié M, Viswanath H, Baldwin PR, Krahe R, Salas R, Amos CI. Genome-wide imaging association study implicates functional activity and glial homeostasis of the caudate in smoking addiction. BMC Genomics. 2017 Sep 19;18(1):740. doi: 10.1186/s12864-017-4124-5. IF: 3.729

90. Rammah A, Walker Whitworth K, Han I, Chan W, Jimenez MD, Strom SS, Bondy ML, Symanski E. A Mixed-Methods Study to Examine the Role of Psychosocial Stress and Air Pollution on Hypertension in Mexican-Origin Hispanics. J Racial Ethn Health Disparities. 2018 Apr 20. doi: 10.1007/s40615-018-0490-1 [Epub ahead of print] PMID: 29679333 IF: 0.11

91. Ricketts CJ, De Cubas AA, Fan H, Smith CC, Lang M, Reznik E, Bowlby R, Gibb EA, Akbani R, Beroukhim R, Bottaro DP, Choueiri TK, Gibbs RA, Godwin AK, Haake S, Hakimi AA, Henske EP, Hsieh JJ, Ho TH, Kanchi RS, Krishnan B, Kwaitkowski DJ, Lui W, Merino MJ, Mills GB, Myers J, Nickerson ML, Reuter VE, Schmidt LS, Shelley CS, Shen H, Shuch B, Signoretti S, Srinivasan R, Tamboli P, Thomas G, Vincent BG, Vocke CD, Wheeler DA, Yang L, Kim WT, Robertson AG; Cancer Genome Atlas Research NetworkA, Spellman PT, Rathmell WK, Linehan WM. The Cancer Genome Atlas Comprehensive Molecular Characterization of Renal Cell Carcinoma. Cell Rep. 2018 Apr 3;23(1):313-326.e5. doi: 10.1016/j.celrep.2018.03.075. PubMed PMID: 29617669. IF: 8.282

92. Ruiz VY, Praska CE, Armstrong G, Kollmeyer TM, Yamada S, Decker PA, Kosel ML, Eckel-Passow JE, Lachance DH, Bainbridge MN, Melin BS, Bondy ML, Jenkins RB. Gliogene Consortium. Molecular Subtyping of Tumors from Patients with Familial Glioma. Neuro Oncol. 2018 May 18;20(6):810-817. doi: 10.1093/neuonc/nox192. PMID: 29040662 IF: 7.371

93. Saltz J, Gupta R, Hou L, Kurc T, Singh P, Nguyen V, Samaras D, Shroyer KR, Zhao T, Batiste R, Van Arnam J; Cancer Genome Atlas Research NetworkA, Shmulevich I, Rao AUK, Lazar AJ, Sharma A, Thorsson V. Spatial Organization and Molecular Correlation of Tumor-Infiltrating Lymphocytes Using Deep Learning on Pathology Images. Cell Rep. 2018 Apr 3;23(1):181-193.e7. doi: 10.1016/j.celrep.2018.03.086. PubMed PMID: 29617659. IF: 8.282

94. Sanchez-Vega F, Mina M, Armenia J, Chatila WK, Luna A, La KC, Dimitriadoy S, Liu DL, Kantheti HS, Saghafinia S, Chakravarty D, Daian F, Gao Q, Bailey MH, Liang WW, Foltz SM, Shmulevich I, Ding L, Heins Z, Ochoa A, Gross B, Gao J, Zhang H, Kundra R, Kandoth C, Bahceci I, Dervishi L, Dogrusoz U, Zhou W, Shen H, Laird PW, Way GP, Greene CS, Liang H, Xiao Y, Wang C, Iavarone A, Berger AH, Bivona TG, Lazar AJ,

17

Hammer GD, Giordano T, Kwong LN, McArthur G, Huang C, Tward AD, Frederick MJ, McCormick F, Meyerson M; Cancer Genome Atlas Research NetworkA, Van Allen EM, Cherniack AD, Ciriello G, Sander C, Schultz N. Oncogenic Signaling Pathways in The Cancer Genome Atlas. Cell. 2018 Apr 5;173(2):321-337.e10. doi: 10.1016/j.cell.2018.03.035. PubMed PMID: 29625050. IF: 30.410

95. Schaub FX, Dhankani V, Berger AC, Trivedi M, Richardson AB, Shaw R, Zhao W, Zhang X, Ventura A, Liu Y, Ayer DE, Hurlin PJ, Cherniack AD, Eisenman RN, Bernard B, Grandori C; Cancer Genome Atlas NetworkA. Pan-cancer Alterations of the MYC Oncogene and Its Proximal Network across the Cancer Genome Atlas. Cell Syst. 2018 Mar 28;6(3):282-300.e2. doi: 10.1016/j.cels.2018.03.003. PubMed PMID: 29596783. IF: 8.982

96. Schmit SL, Edlund CK, Schumacher FR, Gong J, Harrison TA, Huyghe JR, Qu C, Melas M, Van Den Berg DJ, Wang H, Tring S, Plummer SJ, Albanes D, Alonso MH, Amos CI, Anton K, Aragaki AK, Arndt V, Barry EL, Berndt SI, Bezieau S, Bien S, Bloomer A, Boehm J, Boutron-Ruault MC, Brenner H, Brezina S, Buchanan DD, Butterbach K, Caan BJ, Campbell PT, Carlson CS, Castelao JE, Chan AT, Chang-Claude J, Chanock SJ, Cheng I, Cheng YW, Chin LS, Church JM, Church T, Coetzee GA, Cotterchio M, Cruz Correa M, Curtis KR, Duggan D, Easton DF, English D, Feskens EJM, Fischer R, FitzGerald LM, Fortini BK, Fritsche LG, Fuchs CS, Gago-Dominguez M, Gala M, Gallinger SJ, Gauderman WJ, Giles GG, Giovannucci EL, Gogarten SM, Gonzalez-Villalpando C, Gonzalez-Villalpando EM, Grady WM, Greenson JK, Gsur A, Gunter M, Haiman CA, Hampe J, Harlid S, Harju JF, Hayes RB, Hofer P, Hoffmeister M, Hopper JL, Huang SC, Huerta JM, Hudson TJ, Hunter DJ, Idos GE, Iwasaki M, Jackson RD, Jacobs EJ, Jee SH, Jenkins MA, Jia WH, Jiao S, Joshi AD, Kolonel LN, Kono S, Kooperberg C, Krogh V, Kuehn T, Küry S, LaCroix A, Laurie CA, Lejbkowicz F, Lemire M, Lenz HJ, Levine D, Li CI, Li L, Lieb W, Lin Y, Lindor NM, Liu YR, Loupakis F, Lu Y, Luh F, Ma J, Mancao C, Manion FJ, Markowitz SD, Martin V, Matsuda K, Matsuo K, McDonnell KJ, McNeil CE, Milne R, Molina AJ, Mukherjee B, Murphy N, Newcomb PA, Offit K, Omichessan H, Palli D, Cotoré JPP, Pérez-Mayoral J, Pharoah PD, Potter JD, Qu C, Raskin L, Rennert G, Rennert HS, Riggs BM, Schafmayer C, Schoen RE, Sellers TA, Seminara D, Severi G, Shi W, Shibata D, Shu XO, Siegel EM, Slattery ML, Southey M, Stadler ZK, Stern MC, Stintzing S, Taverna D, Thibodeau SN, Thomas DC, Trichopoulou A, Tsugane S, Ulrich CM, van Duijnhoven FJB, van Guelpan B, Vijai J, Virtamo J, Weinstein SJ, White E, Win AK, Wolk A, Woods M, Wu AH, Wu K, Xiang YB, Yen Y, Zanke BW, Zeng YX, Zhang B, Zubair N, Kweon SS, Figueiredo JC, Zheng W, Marchand LL, Lindblom A, Moreno V, Peters U, Casey G, Hsu L, Conti DV, Gruber SB. Novel Common Genetic Susceptibility Loci for Colorectal Cancer. J Natl Cancer Inst. 2018 Jun 16. doi: 10.1093/jnci/djy099. PMID: 991711 IF: 12.589

97. Schraw JM, Henson AT, Scheurer ME, Forman MR. The associations of height-for-age, weight-for-age and weight-for-height with pediatric acute lymphoblastic leukemia. J Pediatr Hematol Oncol. 2017 Jul; 39(5): 376-381. IF: 1.06

98. Schraw JM, Yiu TT, Lupo PJ, Tsavachidis S, Rau R, Bondy ML, Rabin KR, Shen L, Scheurer ME. Maternal folate genes and aberrant DNA hypermethylation in pediatric acute lymphoblastic leukemia. PLoS One. 2018 May 15. doi: 10.1371/journal.pone.0197408 PMID: 29763473 IF: 2.766

99. Schumacher FR, Al Olama AA, Berndt SI, Benlloch S, Ahmed M, Saunders EJ, Dadaev T, Leongamornlert D, Anokian E, Cieza-Borrella C, Goh C, Brook MN, Sheng X, Fachal L, Dennis J, Tyrer J, Muir K, Lophatananon A, Stevens VL, Gapstur SM, Carter BD, Tangen CM, Goodman PJ, Thompson IM Jr, Batra J, Chambers S, Moya L, Clements J, Horvath L,

18

Tilley W, Risbridger GP, Gronberg H, Aly M, Nordström T, Pharoah P, Pashayan N, Schleutker J, Tammela TLJ, Sipeky C, Auvinen A, Albanes D, Weinstein S, Wolk A, Håkansson N, West CML, Dunning AM, Burnet N, Mucci LA, Giovannucci E, Andriole GL, Cussenot O, Cancel-Tassin G, Koutros S, Beane Freeman LE, Sorensen KD, Orntoft TF, Borre M, Maehle L, Grindedal EM, Neal DE, Donovan JL, Hamdy FC, Martin RM, Travis RC, Key TJ, Hamilton RJ, Fleshner NE, Finelli A, Ingles SA, Stern MC, Rosenstein BS, Kerns SL, Ostrer H, Lu YJ, Zhang HW, Feng N, Mao X, Guo X, Wang G, Sun Z, Giles GG, Southey MC, MacInnis RJ, FitzGerald LM, Kibel AS, Drake BF, Vega A, Gómez-Caamaño A, Szulkin R, Eklund M, Kogevinas M, Llorca J, Castaño-Vinyals G, Penney KL, Stampfer M, Park JY, Sellers TA, Lin HY, Stanford JL, Cybulski C, Wokolorczyk D, Lubinski J, Ostrander EA, Geybels MS, Nordestgaard BG, Nielsen SF, Weischer M, Bisbjerg R, Røder MA, Iversen P, Brenner H, Cuk K, Holleczek B, Maier C, Luedeke M, Schnoeller T, Kim J, Logothetis CJ, John EM, Teixeira MR, Paulo P, Cardoso M, Neuhausen SL, Steele L, Ding YC, De Ruyck K, De Meerleer G, Ost P, Razack A, Lim J, Teo SH, Lin DW, Newcomb LF, Lessel D, Gamulin M, Kulis T, Kaneva R, Usmani N, Singhal S, Slavov C, Mitev V, Parliament M, Claessens F, Joniau S, Van den Broeck T, Larkin S, Townsend PA, Aukim-Hastie C, Dominguez MG, Castelao JE, Martinez ME, Roobol MJ, Jenster G, van Schaik RHN, Menegaux F, Truong T, Koudou YA; Profile Study, Xu J, Khaw KT, Cannon-Albright L, Pandha H, Michael A, Thibodeau SN, McDonnell SK, Schaid DJ, Lindstrom S, Turman C, Ma J, Hunter DJ, Riboli E, Siddiq A, Canzian F, Kolonel LN, Le Marchand L, Hoover RN, Machiela MJ, Cui Z, Kraft P; Australian Prostate Cancer BioResource (APCB); IMPACT Study; Canary PASS Investigators; Breast and Prostate Cancer Cohort Consortium (BPC3); PRACTICAL (Prostate Cancer Association Group to Investigate Cancer-Associated Alterations in the Genome) Consortium; Cancer of the Prostate in Sweden (CAPS); Prostate Cancer Genome-wide Association Study of Uncommon Susceptibility Loci (PEGASUS); Genetic Associations and Mechanisms in Oncology (GAME-ON)/Elucidating Loci Involved in Prostate Cancer Susceptibility (ELLIPSE) Consortium, Amos CI, Conti DV, Easton DF, Wiklund F, Chanock SJ, Henderson BE, Kote-Jarai Z, Haiman CA, Eeles RA. Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci. Nat Genet. 2018 Jun 11. doi: 10.1038/s41588-018-0142-8. PMID: 29892016 IF: 27.959

100. Sealock RJ, Thrift AP, El-Serag HB, Sellin J. Long-term follow up of patients with obscure gastrointestinal bleeding examined with video capsule endoscopy. Medicine (Baltimore) 2018;97(29):e11429, PMID: 30024515 IF 2.028

101. Seiler M, Peng S, Agrawal AA, Palacino J, Teng T, Zhu P, Smith PG; Cancer Genome Atlas Research NetworkA, Buonamici S, Yu L. Somatic Mutational Landscape of Splicing Factor Genes and Their Functional Consequences across 33 Cancer Types. Cell Rep. 2018 Apr 3;23(1):282-296.e4. doi: 10.1016/j.celrep.2018.01.088. PubMed PMID: 29617667. IF: 8.282

102. Shiota S, Thrift AP, Green L, Shah R, Verstovsek G, Rugge M, Graham DY, El-Serag HB. Clinical manifestations of Helicobacter pylori-negative gastritis. Clin Gastroenterol Hepatol 2017;15(7):1037-1046, PMID: 28110098 IF: 7.896

103. Takahashi H, Cornish AJ, Sud A, Law PJ, Kinnersley B, Ostrom QT, Labreche K, Eckel-Passow JE, Armstrong GN, Claus EB, Ll'yasova D, Schildkraut J, Barnholtz-Sloan JS, Olson SH, Bernstein JL, Lai RK, Schoemaker MJ, Simon M, Hoffmann P, Nöthen MM, Jöckel KH, Chanock S, Rajaraman P, Johansen C, Jenkins RB, Melin BS, Wrensch MR, Sanson M, Bondy ML, Turnbull C, Houlston RS. Mendelian randomisation study of the

19

relationship between vitamin D and risk of glioma. Sci Rep. 2018 Feb 5;8(1):2339. doi: 10.1038/s41598-018-20844-w. PMID: 29402980 IF: 4.122

104. Tan MC, El-Serag HB, Yu X, Thrift AP. Acid suppression medications reduce risk of oesophageal adenocarcinoma in Barrett’s oesophagus: a nested case-control study in US male veterans. Aliment Pharmacol Ther. 29 June 2018 doi: 10.1111/apt.14895. [Epub ahead of print], PMID: 29956826 IF: 7.357

105. Tan MC, Kanthasamy KA, Yeh AG, Kil D, Pompeii L, Yu X, El-Serag HB, Thrift AP. Factors associated with recurrence of Barrett’s esophagus after radiofrequency ablation. Clin Gastroenterol Hepatol. 11 Jun 2018 doi: 10.1016/j.cgh.2018.05.042. [Epub ahead of print], PMID: 29902646 IF: 7.896

106. Tang Z, Zhang DS, Thrift AP, Patel KK. Impact of cap-assisted colonoscopy on learning curve and quality in colonoscopy: a randomized controlled trial. Gastrointest Endosc 2018; 87(3):723-732, PMID: 28648577 IF: 5.369

107. Tansel A, Katz LH, El-Serag HB, Thrift AP, Parepally M, Shakhatreh MH, Kanwal F. Incidence and determinants of hepatocellular carcinoma in autoimmune hepatitis: a systematic review and meta-analysis. Clin Gastroenterol Hepatol 2017;15(8):1207-1217, PMID: 28215616 IF: 7.896

108. Taylor AM, Shih J, Ha G, Gao GF, Zhang X, Berger AC, Schumacher SE, Wang C, Hu H, Liu J, Lazar AJ; Cancer Genome Atlas Research NetworkA, Cherniack AD, Beroukhim R, Meyerson M. Genomic and Functional Approaches to Understanding Cancer Aneuploidy. Cancer Cell. 2018 Apr 9;33(4):676-689.e3. doi: 10.1016/j.ccell.2018.03.007. Epub 2018 Apr 2. PubMed PMID: 29622463. IF: 27.407

109. Thorsson V, Gibbs DL, Brown SD, Wolf D, Bortone DS, Ou Yang TH, Porta-Pardo E, Gao GF, Plaisier CL, Eddy JA, Ziv E, Culhane AC, Paull EO, Sivakumar IKA, Gentles AJ, Malhotra R, Farshidfar F, Colaprico A, Parker JS, Mose LE, Vo NS, Liu J, Liu Y, Rader J, Dhankani V, Reynolds SM, Bowlby R, Califano A, Cherniack AD, Anastassiou D, Bedognetti D, Rao A, Chen K, Krasnitz A, Hu H, Malta TM, Noushmehr H, Pedamallu CS, Bullman S, Ojesina AI, Lamb A, Zhou W, Shen H, Choueiri TK, Weinstein JN, Guinney J, Saltz J, Holt RA, Rabkin CE; Cancer Genome Atlas Research NetworkA, Lazar AJ, Serody JS, Demicco EG, Disis ML, Vincent BG, Shmulevich L. The Immune Landscape of Cancer. Immunity. 2018 Apr 17;48(4):812-830.e14. doi: 10.1016/j.immuni.2018.03.023. Epub 2018 Apr 5. PubMed PMID: 29628290. IF: 24.082

110. Thrift AP, Chiao EY. Are non-HIV malignancies increased in the HIV-infected population? Curr Infect Dis Rep 2018;20(8):22, PMID: 29804238 IF: 2.085

111. Thrift AP, Vaughan TL, Anderson LA, Whiteman DC, El-Serag HB. External validation of the Michigan Barrett’s esophagus prediction tool. Clin Gastroenterol Hepatol 2017;15(7):1124-1126, PMID: 28300685 IF: 7.896

112. Thrift AP. Barrett’s esophagus and esophageal adenocarcinoma: how common are they really? Dig Dis Sci 2018;63(8):1988-1996, PMID: 29671158 IF: 2.819

113. Thrift AP. Can we accurately predict survival in patients with perihilar cholangiocarcinoma? Clin Gastroenterol Hepatol 2017;15(12):1860-1862, PMID: 28782672

114. Tran KT, McMenamin UC, Hicks B, Murchie P, Thrift AP, Coleman HG, Iversen L, Johnston BT, Lee AJ, Cardwell CR. Proton pump inhibitor and histamine-2 receptor antagonist use and risk of liver cancer in two population-based studies. Aliment Pharmacol Ther 2018;48(1):55-64, PMID: 29741272 IF: 7.357

115. Varn FS, Tafe LJ, Amos CI, Cheng C. Computational immune profiling in lung adenocarcinoma reveals reproducible prognostic associations with implications for

20

immunotherapy. Oncoimmunology. 2018 Mar 15;7(6):e1431084. doi: 10.1080/2162402X.2018.1431084. eCollection 2018. PMID: 29872556 IF: 7.719

116. Wang C, Qin N, Zhu M, Chen M, Xie K, Cheng Y, Dai J, Liu J, Xia Y, Ma H, Jin G, Amos CI, Hu Z, Lin D, Shen H. Metabolome-wide association study identified the association between a circulating polyunsaturated fatty acids variant rs174548 and lung cancer. Carcinogenesis. 2017 Aug 31. doi: 10.1093/carcin/bgx084. IF: 5.334

117. Wang T, Moon JY, Wu Y, Amos CI, Hung RJ, Tardon A, Andrew A, Chen C, Christiani DC, Albanes D, Heijden EHFMV, Duell E, Rennert G, Goodman G, Liu G, Mckay JD, Yuan JM, Field JK, Manjer J, Grankvist K, Kiemeney LA, Marchand LL, Teare MD, Schabath MB, Johansson M, Aldrich MC, Davies M, Johansson M, Tsao MS, Caporaso N, Lazarus P, Lam S, Bojesen SE, Arnold S, Wu X, Zong X, Hong YC, Ho GYF. Pleiotropy of genetic variants on obesity and smoking phenotypes: Results from the Oncoarray Project of The International Lung Cancer Consortium. PLoS One. 2017 Sep 28;12(9):e0185660. doi: 10.1371/journal.pone.0185660. eCollection 2017. IF: 2.766

118. Wang Z, Graham DY, Khan A, Balakrishnan M, Abrams HR, El-Serag HB, Thrift AP. Incidence of gastric cancer in the USA during 1999 to 2013: a 50-state analysis. Int J Epidemiol 2018;47(3):966-975, PMID: 29672681 IF: 7.522

119. Wang Z, Koh WP, Jin A, Wang R, Yuan JM. Telomere length and risk of developing gastric adenocarcinoma: The Singapore Chinese Health Study. Gastric Cancer. 2017 IF: 5.045

120. Wang Z, Shaheen NJ, Whiteman DC, Anderson LA, Vaughan TL, Corley DA, El-Serag HB, Rubenstein JH, Thrift AP. Helicobacter pylori infection is associated with reduced risk of Barrett’s esophagus: an analysis of the Barrett’s and esophageal adenocarcinoma consortium. Am J Gastroenterol. 8 Jun 2018 doi: 10.1038/s41395-018-0070-3. [Epub ahead of print], PMID: 29880962 IF: 10.383

121. Wang Z, Wei Y, Zhang R, Su L, Gogarten SM, Liu G, Brennan P, Field JK, McKay JD, Lissowska J, Swiatkowska B, Janout V, Bolca C, Kontic M, Scelo G, Zaridze D, Laurie CC, Doheny KF, Pugh EK, Marosy BA, Hetrick KN, Xiao X, Pikielny C, Hung RJ, Amos CI, Lin X, Christiani DC. Multi-Omics Analysis Reveals a HIF Network and Hub Gene EPAS1 Associated with Lung Adenocarcinoma. BioMedicine. 2018 Jun;32:93-101. doi: 10.1016/j.ebiom.2018.05.024. Epub 2018 PMID:29859855 IF: 0.11

122. Wang Z, Yang B, Zhang M, Guo W, Wu Z, Wang Y, Jia L, Li S; Cancer Genome Atlas Research NetworkA, Xie W, Yang D. lncRNA Epigenetic Landscape Analysis Identifies EPIC1 as an Oncogenic lncRNA that Interacts with MYC and Promotes Cell-Cycle Progression in Cancer. Cancer Cell. 2018 Apr 9;33(4):706-720.e9. doi: 10.1016/j.ccell.2018.03.006. Epub 2018 Apr 2. PubMed PMID: 29622465. IF: 27.407

123. Way GP, Sanchez-Vega F, La K, Armenia J, Chatila WK, Luna A, Sander C, Cherniack AD, Mina M, Ciriello G, Schultz N; Cancer Genome Atlas Research NetworkA, Sanchez Y, Greene CS. Machine Learning Detects Pan-cancer Ras Pathway Activation in The Cancer Genome Atlas. Cell Rep. 2018 Apr 3;23(1):172-180.e3. doi: 10.1016/j.celrep.2018.03.046. PubMed PMID: 29617658. IF: 8.282

124. Wu W; 23andMe Research Team, Amos CI, Lee JE, Wei Q, Sarin KY, Han J. Inverse Relationship between Vitiligo-Related Genes and Skin Cancer Risk. J Invest Dermatol. 2018 Mar 23. pii: S0022-202X(18)31749-4. doi: 10.1016/j.jid.2018.03.1511. IF: 6.287

125. Xu Y, Wang Y, Liu H, Shi Q, Zhu D, Amos CI, Fang S, Lee JE, Hyslop T, Li X, Han J, Wei Q. Genetic variants in the metzincin metallopeptidase family genes predict melanoma survival. Mol Carcinog. 2017 Aug 10. doi: 10.1002/mc.22716. IF: 3.851

126. Y Li, X Xiao, Y Han, O Gorlova, D Qian, et al. Genome-wide interaction study of smoking

21

behavior and non-small cell lung cancer risk in Caucasian population. Carcinogenesis. 2017. https://doi.org/10.1093/carcin/bgx113 IF: 5.334

127. Zhao Y, Varn FS, Cai G, Xiao F, Amos CI, Cheng C. A P53-Deficiency Gene Signature Predicts Recurrence Risk of Patients with Early-Stage Lung Adenocarcinoma. Cancer Epidemiol Biomarkers Prev. 2018 Jan;27(1):86-95. doi: 10.1158/1055-9965.EPI-17-0478. IF: 4.125

A Includes Quinn Ostrom, MPH, PhD B, C Includes Chris Amos, PhD

https://doi.org/10.1093/carcin/bgx113

22

B. Awards and Honors 1. Amos: Selzman Endowed Chair of Medicine, Baylor College of Medicine 2. Amos: Keynote Speaker, First US-Sino International Conference on Lung Cancer 3. Amos: International Speaker, Integrative Analysis of Lung Cancer Risk and Etiology,

Zhengzhou and Henan Hospital, Chinae 4. Bondy: Visiting Scholar Award, National Cancer Institute 5. Dong: AACR Workshop on Integrative Molecular Epidemiology, Boston, MA 6. Ostrom: AACR Workshop on Integrative Molecular Epidemiology, Boston, MA 7. Ostrom: Doctoral Excellence Award in Epidemiology and Biostatistics, Case Western

Reserve University School of Medicine 8. Ostrom: Junior Investigator Travel Award, Brain Tumor Epidemiology Consortium 9. Schraw: 2nd Place Oral Abstract Presentation, Texas Children's Cancer and

Hematology Centers Annual Symposium 10. Schraw: Junior Investigator Award, Brain Tumor Epidemiology Consortium 11. Schraw: Selected Participant, American Society of Preventative Oncology New

Investigator Workshop 12. Wang: AACR Workshop on Integrative Molecular Epidemiology, Boston, MA

23

C. Books and Book Chapters 1. Amirian E, Liu Y, Ostrom QT, Barnholtz-Sloan J, Bondy M. Nervous System. Cancer

Epidemiology and Prevention, fourth edition. M Thun, M Linet, J Cerhan, C Haiman, D Schottenfeld, eds. Oxford University Press: 2017.

2. Ostrom QT, Barnholtz-Sloan J. Biospecimen Repositories in the Precision Medicine Era: Perspectives from a Biobanker in the "Trenches.” Specimen Science: Ethics and Policy Implications. SM Rivera, BE Bierer, H Fernandez Lynch, IG Cohen, eds. The MIT Press: 2017.

3. Ostrom QT, Gittleman H, Stetson L, Virk S, Barnholtz-Sloan JS. Epidemiology of Intracranial Gliomas. Prog Neurol Surg. 2018;30:1-11. doi: 10.1159/000464374. Epub 2017 Dec 14. PubMed PMID: 29241168.

4. Ostrom QT, Wright C, Barnholtz-Sloan JS. Brain Metastases: Epidemiology. In: Schiff D, van den Bent, MJ, eds., Metastatic Disease of the Nervous System, San Diego: Elsevier BV, 2018: 27-42.

5. Thrift AP. Epidemiology of Esophageal Adenocarcinoma in RB Cameron, O Olevsky, D Gage, ed., Modern Thoracic Oncology, World Scientific, 2017.

24

D. Press 1. Amos, Bondy: Houston Chronicle. Newest state cancer grants lure back former Houston

research star. https://www.houstonchronicle.com/local/prognosis/article/Newest-state-cancer-grants-lure-former-Houston-11824855.php

2. Bondy: CW39 Houston. Wristbands at Baylor College of Medicine helps to study Harvey. https://cw39.com/2017/09/22/wristbands-at-baylor-college-of-medicine-helps-to-study-harvey/

3. Bondy: Houston Chronicle. Harvey flood victims hope special wristbands will help scientists understand environmental exposures. https://www.houstonchronicle.com/news/houston-texas/article/Harvey-flood-victims-hope-special-wristbands-will-12230622.php

4. Bondy: KHOU 11. Harvey victims wear wristbands to track chemical exposure. https://www.khou.com/article/news/health/harvey-victims-wear-wristbands-to-track-chemical-exposure/478342064

5. Bondy: New York Times. The brain cancer that keeps killing baseball players. https://www.nytimes.com/2017/08/14/sports/baseball/brain-cancer-phillies-daulton.html

6. Bondy: News Week. Are Hurricane Harvey floodwaters making people sick? These wristbands could tell. https://www.newsweek.com/after-hurricane-harvey-these-wristbands-could-tell-houston-residents-if-theyve-673962

7. Ostrom: Laboratory Equipment. Men, women have different genetic risk factors for developing brain cancer. https://www.laboratoryequipment.com/news/2018/06/men-women-have-different-genetic-risk-factors-developing-brain-cancer

8. Ostrom: R&D Mag. Men and women have different genetic risk factors for developing brain cancer. https://www.rdmag.com/news/2018/06/men-and-women-have-different-genetic-risk-factors-developing-brain-cancer

9. Ostrom: ScienceDaily. Men and women have different genetic risk factors for developing brain cancer. https://www.sciencedaily.com/releases/2018/06/180628151931.htm

10. Schraw: ASCO Post. AACR 2018: Children with non-chromosomal birth defects may face higher risk of several childhood cancers. http://www.ascopost.com/News/58730

11. Schraw: Ecancer. A link between non-chromosomal birth defects and cancer. https://ecancer.org/conference/1047-aacr-2018/video/6824/a-link-between-non-chromosomal-birth-defects-and-cancer.php

12. Schraw: Healio. Non-chromosomal birth defects linked to higher risk for some childhood cancers. https://www.healio.com/hematology-oncology/pediatric-oncology/news/online/%7B6c290563-d671-4860-8309-7ff69f5870cf%7D/nonchromosomal-birth-defects-linked-to-higher-risk-for-some-childhood-cancers

13. Schraw: Memorial Sloan Kettering Cancer Center. Certain birth defects may raise risk of childhood cancer. https://www.mskcc.org/blog/aacr-18-birth-defect-childhood

14. Schraw: Oncology Times. Risk of cancers increased among children with non-chromosomal birth defects. http://know.lww.com/oncology-times/articles/childhood-cancers.html

15. Schraw: Tech Times. Children with non-chromosomal birth defects have almost thrice the risk of childhood cancer. https://www.techtimes.com/articles/225291/20180417/children-with-non-chromosomal-birth-defects-have-almost-thrice-the-risk-of-pediatric-cancer.htm

16. Schraw: The Scientist. Birth defects linked to increased risk of childhood cancer. http://www.ascopost.com/News/58730

25

17. Wang: AACR. Short-acting calcium channel blockers were associated with increased risk of pancreatic cancer in postmenopausal women. https://www.aacr.org/Newsroom/Pages/News-Release-Detail.aspx?ItemID=1185#.W23E6VVKiUk

18. Wang: Healio. Calcium channel blockers may increase risk for pancreatic cancer. https://www.healio.com/hematology-oncology/gastrointestinal-cancer/news/online/%7Befa4c934-a723-4d9f-9a79-52bad6e74c56%7D/calcium-channel-blockers-may-increase-risk-for-pancreatic-cancer

19. Wang: HealthDay. Some blood pressure meds tied to pancreatic cancer risk in women. https://consumer.healthday.com/cancer-information-5/pancreatic-cancer-news-105/some-blood-pressure-meds-tied-to-pancreatic-cancer-risk-in-women-732998.html

20. Wang: LA Times. Attention women: Your choice of blood pressure medicine may affect your risk of pancreatic cancer. http://www.latimes.com/science/sciencenow/la-sci-sn-pancreatic-cancer-hypertension-20180417-story.html

26

E. Professional Organization/Association Offices Held 1. Bondy: AACR, MEG Steering Committee, Chairperson 2. Bondy: American College of Epidemiology, Board of Directors 3. Bondy: American Society of Prevention Oncology (ASPO) Program Committee 4. Bondy: Central Brain Tumor Registry of the United States, Board Member 5. Bondy: Duke Cancer Institute External Scientific Advisory Committee 6. Bondy: Kimmel Cancer Center External Scientific Advisory Committee 7. Bondy: Masonic Cancer Center External Advisory Board 8. Bondy: NCI Board of Scientific Advisors, Subcommittee on Global Cancer Research 9. Bondy: OSUCCC IRP Population Science Review Committee 10. Bondy: Perlmutter Cancer Center External Advisory Board 11. Bondy: St. Jude Children’s Hospital, Memphis, TN, External Advisor 12. Bondy: Susan G. Komen for the Cure, Scientific Advisory Board, Houston Medical

Advisory Council, & Strategic Mission Committee 13. Bondy: University of Minnesota Cancer Center, External Scientific Advisory Board, 14. Bondy: University of Washington EDGE Center Scientific Advisory Board 15. Liu: American Society of Human Genetics 2017 Essay Contest, Program Reviewer 16. Ostrom: North American Association of Central Cancer Registries, Data Assessment

Working Group 17. Spitz: MD Anderson Cancer Center, Prostate Cancer SPORE, External Advisory

Committee 18. Spitz: National Cancer Advisory Board, Subcommittee on Population Science,

Epidemiology, and Disparities 19. Spitz: Northwestern University, T32 for Behavioral and Psychosocial Research

Training in Cancer Prevention and Control, External Advisory Board 20. Spitz: Tisch Cancer Center, Mount Sinai Medical Center, External Advisory Committee 21. Spitz: University of Chicago Comprehensive Cancer Center, External Advisory

Committee 22. Spitz: University of Kentucky Markey Cancer Center, External Advisory Committee 23. Spitz: Yale Cancer Center, Lung Cancer SPORE, External Advisory Board 24. Thrift: Barrett's and Esophageal Adenocarcinoma Consortium (BEACON), Steering

Committee

27

F. Editorial Board Memberships and Editorial Positions

Impact factors of 10 JCR-rated journals edited by section members (mean 4.0) Journal Impact Factor: <= 1 1 – 4 4 - 7 >= 7 Edited Journals: 1 2 6 1 Percentage of Total: 10% 20% 60% 10%

1. Amos: Genes and Immunity, Editorial Board (IF 2.339) 2. Amos: Human Molecular Genetics, Associate Editor (IF 5.985) 3. Amos: Journal of Functional and Comparative Genomics, Editorial Board (IF 1.94) 4. Bondy: Cancer Epidemiology, Associate Editor (IF 4.554) 5. Bondy: Frontiers in Applied Genetic Epidemiology, Review Editor (IF 4.151) 6. Bondy: Molecular and Translational Epidemiology, Editorial Board 7. Bondy: Scientific Reports – A Nature Journal, Editorial Board (IF 4.609) 8. Bondy: The Application of Clinical Genetics, Honorary Editorial Board (IF 4.2) 9. Dong: Annals of Translational Medicine, Editorial Board (IF .2) 10. Dong: Austin Cardiology, Editorial Board 11. Dong: EC Neurology, Editorial Board 12. Dong: Frontiers in Genetics, Review Editor (IF 4.151) 13. Dong: Journal of Cancer Research Forecast, Editorial Board 14. Dong: JSM Biology, Editorial Board 15. Thrift: Clinical Gastroenterology and Hepatology, Associate Editor (IF 7.896)

28

G. Grants 1. Amos (PI): Data Coordinating and Management Group for Molecular

Characterization of Screen Detected Lesions Network, Supplement 1 Molecular Studies and Single Cell Sequencing; NIH/NCI; $432,000 annually (9/1/2018 - 8/31/2020)

2. Amos (PI): Data Coordinating and Management Group for Molecular Characterization of Screen Detected Lesions Network; NIH/NCI; $300,000 annually (9/1/2015 - 8/31/2020)

3. Amos (PI): Genome-Wide Association Study (GWAS) in Hepatocellular Carcinoma (HCC); NIH/NCI; $473,538 annually (04/01/2015 - 06/30/2019)

4. Amos (PI): Integrative Analysis of Lung Cancer Etiology and Risk; NCI; $473,538 annually (9/1/17 - 5/30/22)

5. Amos (Subcontract PI): Genetic Susceptibility and Risk Model for Pancreatic Cancer; NIH/NCI; $13,193 annually (7/1/14 - 6/30/18)

6. Bondy (Coinvestigator): Baylor College of Medicine Cancer Center; NIH/NCI; $2,020,895 annually (07/01/2007 - 06/30/2020)

7. Bondy (Coinvestigator): Center for Translational Environmental Health Research; NIH/NIEHS; $84,000 (04/01/2013 - 12/31/2018)

8. Bondy (Coinvestigator): Toxicity Profiling: Creating Novel Paradigms to Personalize Cancer Treatment; 06/07/13 - 03/31/18

9. Bondy (PI): Breast Cancer Risk Assessment Using Copy Number Variation; Susan G. Komen Foundation; $160,000 annually (09/01/2011 - 08/31/2017)

10. Bondy (PI): Risk Prediction for ER Negative Breast Cancer Recurrence; NIH/NCI; $2,977,314 (01/01/2013 - 12/31/2017)

11. Liu (PI): Lung Cancer Prediction Models Incorporating Exome Data from Extreme Phenotypes; NIH/NCI; (08/2014 - 08/2019)

12. Spitz (Coinvestigator): Incorporating Biomarkers to Improve Lung Cancer Risk Prediction; NIH; $21,647 (12/01/2015 - 11/30/2018)

13. Spitz (Coinvestigator): Integrative Molecular Epidemiology Workshop; AACR; $249,213 annually (09/01/2013 - 08/31/2018)

14. Spitz (PI): Cancer Prevention Post-Graduate Training Program in Integrative Epidemiology; Cancer Prevention and Research Institute of Texas; $300,401 (03/01/2016 - 02/28/2021)

15. Thrift (Coinvestigator): DCC HHS Smoking Cessation Treatment Program; NCI P30 Cancer Center Administrative Supplement for Tobacco Use Treatment in Cancer Patients; total direct costs $315,457 (07/01/2017 - 06/30/2019)

16. Thrift (Coinvestigator): Prevalence and predictors of nonalcoholic fatty liver disease (NAFLD) in Veterans; VA CSR&D Research Awards; total direct costs $600,000 (10/01/2017 - 09/30/2021)

17. Thrift (PI): Admixture mapping of cirrhosis and Hepatocellular carcinoma in African Americans; Dan L. Duncan Comprehensive Cancer Center Pilot Grant; total direct costs $50,000 (06/01/2018 - 05/30/2019)

18. Thrift (PI): Application of natural language processing to identify dysplasia among a national cohort of veterans with Barrett’s esophagus; NIH; total direct costs $34,821 (02/01/2017 - 01/31/2018)

19. Thrift (PI): PREVENT HCC – through Screening, Vaccination and Treatment of Viral Hepatitis; Cancer Prevention and Research Institute of Texas (CPRIT) Prevention Program; total direct costs $1,492,052 (08/31/2016 - 08/30/2019)

29

20. Thrift (PI): Risk and Predictors of Esophageal and Esophagogastric Junction Adenocarcinomas in HIV-infected Individuals; NAID/NIH/DHHS; total direct costs $299,992 (06/01/2016 - 05/31/2018)

1 | P a g e

Gastroenterology&

Hepatology

ANNUALREPORT

ACADEMICYEAR2018

CONTENTS A. Publications ………………………………………………………………………………………………………..02 B. DDW 2018 Presentations and Abstracts…………………………………………………………….....10

a. Invited Lectures……………………………………………………………………….10 b. Oral Presentations……………………………………………………………………11 c. Poster Presentations…………………………………………………………………12

C. Press……………………………………………………………………………………………………………………16 D. Grants………………………………………………………………………………………………………………….17

2 | P a g e

JULY 2017 – JUNE 2018 PUBLICATIONS 1. Lo YH, Noah TK, Chen MS, Zou W, Borras E, Vilar E, Shroyer NF. Induces Quiescence of Colorectal

Cancer Cells by Changing the Transcriptional Targets of β‐catenin. Gastroenterology. 2017

Jul;153(1):205‐218.e8.

2. Múnera JO, Sundaram N, Rankin SA, Hill D, Watson C, Mahe M, Vallance JE, Shroyer NF,

Sinagoga KL, Zarzoso‐Lacoste A, Hudson JR, Howell JC, Chatuvedi P, Spence JR, Shannon JM, Zorn

AM, Helmrath MA, Wells JM. Differentiation of Human Pluripotent Stem Cells into Colonic

Organoids via Transient Activation of BMP Signaling. Cell Stem Cell. 2017 Jul 6;21(1):51‐64.e6.

3. Thorell K, Bengtsson‐Palme J, Liu OH, Gonzales RV, Nookaew I, Rabeneck L, Paszat L, Graham

DY, Nielsen J, Lundin SB, Sjöling Å. In vivo analysis of the viable microbiota and Helicobacter

pylori transcriptome in gastric infection and early stages of carcinogenesis. Infection and

immunity. 2017 Jul 10:IAI‐00031.

4. Tanaka S, Nagashima H, Cruz M, Uchida T, Uotani T, Abreu JA, Mahachai V, Vilaichone RK,

Ratanachu‐ek T, Tshering L, Graham DY. Interleukin‐17C in human Helicobacter pylori gastritis.

Infection and immunity. 2017 Jul 24:IAI‐00389.

5. Shukla R, Salem M, Hou JK. Use and Barriers to Chromoendoscopy for Dysplasia Surveillance in

Inflammatory Bowel Disease. World J Gastrointest Endosc. 2017 Aug 16;9(8):359‐367.

6. Balakrishnan M, George R, Sharma A, Graham DY. Changing Trends in Stomach Cancer

Throughout the World. Curr Gastroenterol Rep. 2017 Aug;19(8):36.

7. Feagins LA, Waljee A, Hou JK, Gu P, Kanjo S, Rudrapatna V, Cipher DJ, Govani S, Gaidos J.

Incidence of and Predictors for Early Discontinuation of Biological Therapies in Veteran Patients

with Inflammatory Bowel Disease. Inflamm Bowel Dis. 2017 Aug;23(8):1434‐1439.

8. Parian A, Limketkai B, Koh J, Brant SR, Bitton A, Cho JH, Duerr RH, McGovern DP, Proctor DD,

Regueiro MD, Rioux JD, Schumm P, Taylor KD, Silverberg MS, Steinhart AH, Hernaez R, Lazarev

M. Appendectomy does not decrease the risk of future colectomy in UC: results from a large

cohort and meta‐analysis. Gut. 2017 Aug;66(8):1390‐1397.

9. El‐Serag HB, Zhu AX, Johnson MS. The treatment path in hepatocellular carcinoma. Clin Adv

Hematol Oncol. 2017 Aug;15(Suppl 9):1‐20.

10. El‐Serag HB. Advances in the management of hepatocellular carcinoma. Clinical advances in

hematology & oncology: H&O. 2017 Aug;15(8):2.

11. Abdelfatah MM, Barakat M, Lee H, Kim JJ, Uedo N, Grimm I, Othman MO. The incidence of

lymph node metastasis in early gastric cancer according to the expanded criteria in comparison

with the absolute criteria of the Japanese Gastric Cancer Association: a systematic review of the

literature and meta‐analysis. Gastrointestinal endoscopy. 2017 Sep 28.

12. Hou JK, Jones M, Lum D. Opening Doors for Urgent IBD Access: Harder than It Looks. Inflamm

Bowel Dis. 2017 Sep;23(9):1470‐1472

13. Malaty HM, Lo GH, Hou JK. Characterization and Prevalence of Spondyloarthritis and Peripheral

Arthritis among Patients with Inflammatory Bowel Disease. Clin Exp Gastroenterol. 2017 Sep

27;10:259‐263.

14. Hou JK, Lewis JD. Dietary Recommendations for Ulcerative Colitis Remain a Mystery. Clin

Gastroenterol Hepatol. 2017 Sep;15(9):1350‐1352.

3 | P a g e

15. Graham DY, Lu H, Shiotani A. Failure of optimized dual proton pump inhibitor amoxicillin

therapy: What now?. Saudi journal of gastroenterology: official journal of the Saudi

Gastroenterology Association. 2017 Sep;23(5):265.

16. Kanwal F, Pyne JM, Tavakoli‐Tabasi S, Nicholson S, Dieckgraefe B, Storay E, Goetz MB, Kramer

JR, Smith D, Sansgiry S, Tansel A, Gifford AL, Asch SM. A Randomized Trial of Off‐Site

Collaborative Care for Depression in Chronic Hepatitis C Virus. Health Serv Res. 2017 Sep 11.

17. Hernaez R, Thrift AP. High negative predictive value, low prevalence, and spectrum effect:

caution in the interpretation. Clin Gastroenterol Hepatol. 2017 Sep;15(9):1355‐1358.

18. Maret‐Ouda J, Wahlin K, El‐Serag HB, Lagergren J. Association between laparoscopic antireflux

surgery and recurrence of gastroesophageal reflux. Jama. 2017 Sep 12;318(10):939‐46.

19. Massarweh NN, El‐Serag HB. Epidemiology of hepatocellular carcinoma and intrahepatic

cholangiocarcinoma. Cancer Control. 2017 Sep 6;24(3):1073274817729245.

20. Graham DY. Illusions regarding Helicobacter pylori clinical trials and treatment guidelines. Gut.

2017 Sep 21:gutjnl‐2017.

21. Mindikoglu AL, Opekun AR, Sood GK, Devaraj S. Impact of Time‐Restricted Feeding and Dawn‐

to‐Sunset Fasting on Circadian Rhythm, Obesity, Metabolic Syndrome, and Nonalcoholic Fatty

Liver Disease. Gastroenterology research and practice. 2017;2017.

22. Redman JS, Natarajan Y, Hou JK, Wang J, Hanif M, Feng H, Kramer JR, Desiderio R, Xu H, El‐

Serag HB, Kanwal F. Accurate Identification of Fatty Liver Disease in Data Warehouse Utilizing

Natural Language Processing. Dig Dis Sci. 2017 Oct;62(10):2713‐2718.

23. Abdelfatah MM, Elhanafi S, Zuckerman MJ, Othman MO. Correlation between adenoma

detection rate and novel quality indicators for screening colonoscopy. A proposal for quality

measures tool kit. Scand J Gastroenterol. 2017 Oct;52(10):1148‐1157.

24. Hou JK, Vanga RR, Thakur E, Gonzalez I, Willis D, Dindo L. One‐Day Behavioral Intervention for

Patients With Inflammatory Bowel Disease and Co‐Occurring Psychological Distress. Clin

Gastroenterol Hepatol. 2017 Oct;15(10):1633‐1634

25. Kanwal F, Kramer J, Asch SM, Chayanupatkul M, Cao Y, El‐Serag HB. Risk of Hepatocellular

Cancer in HCV Patients Treated with Direct Acting Antiviral Agents. Gastroenterology. 2017

Oct;153(4):996‐1005.e1.

26. Ngamruengphong S, Inoue H, Ujiki MB, Patel LY, Bapaye A, Desai PN, Dorwat S, Nakamura J,

Hata Y, Balassone V, Onimaru M, Ponchon T, Pioche M, Roman S, Rivory J, Mion F, Garros A,

Draganov PV, Perbtani Y, Abbas A, Pannu D, Yang D, Perretta S, Romanelli J, Desilets D, Hayee B,

Haji A, Hajiyeva G, Ismail A, Chen YI, Bukhari M, Haito‐Chavez Y, Kumbhari V, Saxena P, Talbot

M, Chiu PW, Yip HC, Wong VW, Hernaez R, Maselli R, Repici A, Khashab MA. Efficacy and Safety

of Peroral Endoscopic Myotomy for Treatment of Achalasia After Failed Heller Myotomy. Clin

Gastroenterol Hepatol. 2017 Oct;15(10):1531‐1537.e3.

27. Pandya P, Kanwal F. Adding to the evidence base: Effectiveness of hepatocellular carcinoma

surveillance in clinical practice. Hepatol Commun. 2017 Oct 6;1(8):723‐725.

28. El‐Serag HB, Margaret M, Alkek AB. Current Status of Sorafenib Use for Treatment of

Hepatocellular Carcinoma. Gastroenterology & hepatology. 2017 Oct;13(10):623.

29. Tau JA, Pappas SC. Editorial: hepatitis C Virus (HCV) Disease progression ‐ HCV Cure and the

Elimination of the "Ethnic Slope”. Aliment Pharmacol Ther. 2017 Nov;46(10):1011‐1012.

4 | P a g e

30. Chen Y, Zhou W, Roh T, Estes MK, Kaplan DL. In vitro enteroid‐derived three‐dimensional tissue

model of human small intestinal epithelium with innate immune response. PLoS One. 2017 Nov

29;12(11):e0187880.

31. Lin M, Kramer J, White D, Cao Y, Tavakoli‐Tabasi S, Madu S, Smith D, Asch SM, El‐Serag HB,

Kanwal F. Barriers to Hepatitis C Treatment in the Era of Direct Acting Antiviral Agents. Aliment

Pharmacol Ther. 2017 Nov;46(10):992‐1000.

32. Kramer JR, El‐Serag HB, Taylor TJ, White DL, Asch SM, Frayne SM, Cao Y, Smith DL, Kanwal F.

Hepatitis C Virus‐Related Complications are Increasing in Women Veterans: A National Cohort

Study. J Viral Hepat. 2017 Nov;24(11):955‐965.

33. Hassan MM, Botrus G, Abdel‐Wahab R, Wolff RA, Li D, Tweardy D, Phan AT, Hawk E, Javle M, Lee

JS, Torres HA, Rashid A, Lenzi R, Hassabo HM, Abaza Y, Shalaby AS, Lacin S, Morris J, Patt YZ,

Amos CI, Khaderi SA, Goss JA, Jalal PK, Kaseb AO. Estrogen Replacement Reduces Risk and

Increases Survival Times of Women With Hepatocellular Carcinoma. Clin Gastroenterol Hepatol.

2017 Nov;15(11):1791‐1799.

34. Kaur M, Singapura P, Kalakota N, Cruz G, Shukla R, Ahsan S, Tansel A, Thrift AP, El‐Serag HB.

Factors That Contribute to Indeterminate Results From the QuantiFERON‐TB Gold In‐Tube Test

in Patients With Inflammatory Bowel Disease. Clin Gastroenterol Hepatol. 2017 Nov 23. pii:

S1542‐3565(17)31411‐8.

35. Hu Y, Wan JH, Li XY, Zhu Y, Graham DY, Lu NH. Systematic review with meta‐analysis: the global

recurrence rate of Helicobacter pylori. Alimentary pharmacology & therapeutics. 2017

Nov;46(9):773‐9.

36. Kourkoumpetis T, Jarbrink‐Sehgal ME. Melanoma metastatic to the duodenum. N Engl J Med.

2017 Dec 21;377(25):e34.

37. Wangda S, Richter JM, Kuenzang P, Wangchuk K, Choden T, Tenzin K, Malaty HM. Epidemiology

of Helicobacter pylori infection in asymptomatic schoolchildren in Bhutan. Helicobacter. 2017

Dec;22(6).

38. Rana A, Witte ED, Halazun KJ, Sood GK, Mindikoglu AL, Sussman NL, Vierling JM, Kueht ML,

Galvan NTN, Cotton RT, O'Mahony CA, Goss JA. Liver transplant length of stay (LOS) index: A

novel predictive score for hospital length of stay following liver transplantation. Clin Transplant.

2017 Dec;31(12).

39. Camilleri M, Wilcox CM, El‐Serag HB, Kanwal F. Anniversary Tribute From the Editors of Clinical

Gastroenterology and Hepatology. Clinical Gastroenterology and Hepatology. 2017 Dec

1;15(12):1823‐7.

40. Ayub K, Ketwaroo G, Abudayyeh S, Ibrahim A, Cole RA, Brumfield‐Brown R, Qureshi WA,

Rabeneck L, Graham DY. Mechanical Colon Cleansing for Screening Colonoscopy: a Randomized

Controlled Trial. J Dig Dis. 2017 Dec;18(12):691‐697.

41. Royse KE, El‐Serag HB, Chen L, White DL, Hale L, Sangi‐Haghpeykar H, Jiao L. Sleep Duration and

Risk of Liver Cancer in Postmenopausal Women. J Womens Health (Larchmt). 2017

Dec;26(12):1270‐1277.

42. Kourkoumpetis T, Jarbrink‐Sehgal ME. Melanoma metastatic to the duodenum. N Engl J Med.

2017 Dec 21;377(25):e34.

43. Block TM, Alter H, Brown N, Brownstein A, Brosgart C, Chang KM, Chen PJ, Cohen C, El‐Serag H,

Feld J, Gish R. Research priorities for the discovery of a cure for chronic hepatitis B: report of a

workshop. Antiviral research. 2017 Dec 14.

5 | P a g e

44. Graham DY. Letter: questions regarding the diagnostic performance of serum assays for

atrophic gastritis. Aliment Pharmacol Ther. 2017 Dec;46(11‐12):1117‐1118.

45. Jiao L, Chen L, White DL, Tinker L, Chlebowski RT, Van Horn LV, Richardson P, Lane D, Sangi‐

Haghpeykar H, El‐Serag HB. Low Fat‐Dietary Pattern and Pancreatic Cancer Risk in the Women’s

Health Initiative Dietary Modification Randomized Controlled Trial. J Natl Cancer Inst. 2018 Jan

1;110(1).

46. Zou WY, Blutt SE, Zeng XL, Chen MS, Lo YH, Castillo‐Azofeifa D, Klein OD, Shroyer NF, Donowitz

M, Estes MK. Epithelial WNT Ligands are Essential Drivers of Intestinal Stem Cell Activation. Cell

Rep. 2018 Jan 23;22(4):1003‐1015.

47. Tayob N, Richardson P, White DL, Yu X, Davila JA, Kanwal F, Feng Z, El‐Serag HB. Evaluating

screening approaches for hepatocellular carcinoma in a cohort of HCV related cirrhosis patients

from the Veteran's Affairs Health Care System. BMC Med Res Methodol. 2018 Jan 4;18(1):1.

48. Pratt PK Jr, David N, Weber HC, Little FF, Kourkoumpetis T, Patts GJ, Weinberg J, Farraye FA.

Antibody Response to Hepatitis B Virus Vaccine is Impaired in Patients With Inflammatory Bowel

Disease on Infliximab Therapy. Inflamm Bowel Dis. 2018 Jan 18;24(2):380‐386.

49. Rana A, Ackah RL, Webb GJ, Halazun KJ, Vierling JM, Liu H, Wu MF, Yoeli D, Kueht M,

Mindikoglu AL, Sussman NL, Galván NT, Cotton RT, O'Mahony CA, Goss JA. No Gains in Long‐

Term Survival After Liver Transplantation Over the Past Three Decades. Ann Surg. 2018 Jan 4.

50. Shukla R, Thakur E, Bradford A, Hou JK. Caregiver Burden in Adults With Inflammatory Bowel

Disease. Clin Gastroenterol Hepatol. 2018 Jan;16(1):7‐15.

51. Zeuzem S, Foster GR, Wang S, Asatryan A, Gane E, Feld JJ, Asselah T, Bourlière M, Ruane PJ,

Wedemeyer H, Pol S, Flisiak R, Poordad F, Chuang WL, Stedman CA, Flamm S, Kwo P, Dore GJ,

Sepulveda‐Arzola G, Roberts SK, Soto‐Malave R, Kaita K, Puoti M, Vierling J, Tam E, Vargas HE,

Bruck R, Fuster F, Paik SW, Felizarta F, Kort J, Fu B, Liu R, Ng TI, Pilot‐Matias T, Lin CW, Trinh R,

Mensa FJ. Glecaprevir‐Pibrentasvir for 8 or 12 Weeks in HCV Genotype 1 or 3 Infection. N Engl J

Med. 2018 Jan 25;378(4):354‐369.

52. Bhakta D, Graham DY, Chan J, El‐Serag HB. Lessons From Using Culture‐Guided Treatment After

Referral for Multiple Treatment Failures for Helicobacter pylori Infection. Clin Gastroenterol

Hepatol. 2018 Jan 3. pii: S1542‐3565(17)31538‐0.

53. Hu Y, Wan JH, Li XY, Zhu Y, Graham DY, Lu NH. s Aliment Pharmacol Ther. 2018 Jan;47(1):132‐

133.

54. Rugge M, Meggio A, Pravadelli C, Barbareschi M, Fassan M, Gentilini M, Zorzi M, De Pretis G,

Graham DY, Genta RM. Gastritis staging in the endoscopic follow‐up for the secondary

prevention of gastric cancer: a 5‐year prospective study of 1755 patients. Gut. 2018 Jan 6:gutjnl‐

2017.

55. Graham DY, Miftahussurur M. Helicobacter pylori urease for diagnosis of Helicobacter pylori

infection: A mini‐review. Journal of Advanced Research. 2018 Jan 31.

56. Mapakshi S, Kramer JR, Richardson P, El‐Serag HB, Kanwal F. Positive Predictive Value of ICD‐10

Codes for Cirrhosis and its Related Complications. Clin Gastroenterol Hepatol. 2018 Feb 1. pii:

S1542‐3565(18)30113‐7.

57. Mindikoglu AL, Pappas SC. New Developments in Hepatorental Syndrome. Clin Gastroenterol

Hepatol. 2018 Feb;16(2):162‐177.e1.

58. Balakrishnan M, El‐Serag HB. Editorial: NAFLD‐related hepatocellular carcinoma ‐ increasing or

not? With or without cirrhosis? Aliment Pharmacol Ther. 2018 Feb;47(3):437‐438.

6 | P a g e

59. Rana A, Sigireddi RR, Halazun KJ, Kothare A, Wu MF, Liu H, Kueht ML, Vierling JM, Sussman NL,

Mindikoglu AL, Miloh T, Galvan NTN, Cotton RT, O'Mahony CA, Goss JA. Predicting Liver

Allograft Discard: The Discard Risk Index. Transplantation. 2018 Feb 26.

60. Hammad T, Khan MA, Alastal Y, Lee W, Nawras A, Ismail MK, Kahaleh M. Efficacy and Safety of

Lumen‐Apposing Metal Stents in Management of Pancreatic Fluid Collections: Are They Better

Than Plastic Stents? A Systematic Review and Meta‐Analysis. Dig Dis Sci. 2018 Feb;63(2):289‐

301.

61. Webb GJ, Rana A, Hodson J, Akhtar MZ, Ferguson JW, Neuberger JM, Vierling JM, Hirschfield

GM. Twenty‐Year Comparative Analysis of Patients With Autoimmune Liver Diseases on

Transplant Waitlists. Clin Gastroenterol Hepatol. 2018 Feb;16(2):278‐287.e7.

62. Mittal S, Kramer JR, Omino R, Chayanupatkul M, Richardson PA, El‐Serag HB, Kanwal F. Role of

Age and Race in the Risk of Hepatocellular Carcinoma in Veterans with Hepatitis B Virus

Infection. Clin Gastroenterol Hepatol. 2018 Feb;16(2):252‐259.

63. Nell S, Estibariz I, Krebes J, Bunk B, Graham DY, Overmann J, Song Y, Spröer C, Yang I, Wex T,

Korlach J, Malfertheiner P, Suerbaum S. Genome and Methylome Variation in Helicobacter

Pylori with Cag Pathogenicity Island During Early Stages of Human Infection. Gastroenterology.

2018 Feb;154(3):612‐623.e7.

64. Ngamruengphong S, Sharaiha R, Sethi A, Siddiqui A, DiMaio CJ, Gonzalez S, Rogart J, Jagroop S,

Widmer J, Im J, Hasan RA, Laique S, Gonda T, Poneros J, Desai A, Wong K, Villgran V, Brewer

Gutierrez O, Bukhari M, Chen YI, Hernaez R, Hanada Y, Sanaei O, Agarwal A, Kalloo AN,

Kumbhari V, Singh V, Khashab MA. Fully‐covered metal stents with endoscopic suturing vs.

partially‐covered metal stents for benign upper gastrointestinal diseases: a comparative study.

Endosc Int Open. 2018 Feb;6(2):E217‐E223.

65. Graham DY, Dore MP. Update on Use of Vonoprazan: a Competitive Acid Blocker (P‐CAG).

Gastroenterology. 2018 Feb;154(3):462‐466..

66. Bernica J, Elhanafi S, Kalakota N, Jia Y, Dodoo C, Dwivedi A, Sealock RJ, Patel K, Raijman I,

Zuckerman MJ, Othman MO. Cholangioscopy Is Safe and Feasible in Elderly Patients. Clin

Gastroenterol Hepatol. 2018 Mar;16(8):1293‐1299.e2.

67. Mindikoglu AL, Pappas SC. Predictors of Response to Terlipressin in Hepatorenal Syndrome. Clin

Gastroenterol Hepatol. 2018 Mar 15;16(7):1174.

68. Mindikoglu AL, Opekun AR, Mitch WE, Magder LS, Christenson RH, Dowling TC, Weir MR,

Seliger SL, Howell CD, Raufman JP, Rana A, Goss JA, Khaderi SA, Vierling JM. Cystatin C is a

Gender‐Neutral Glomerular Filtration Rate Biomarker in Patients with Cirrhosis. Dig Dis Sci. 2018

Mar;63(3):665‐675.

69. Tang Z, Zhang DS, Thrift AP, Patel KK. Impact of Cap‐assisted Colonoscopy on Learning Curve

and Quality in Colonoscopy: a Randomized Controlled Trial. Gastrointest Endosc. 2018

Mar;87(3):723‐732.e3.

70. Kourkoumpetis T, Royse KE, Chen L, Ravishankar M, Ittmann M, El‐Serag HB, Jiao L. Differential

Expression of Tight Junctions and Cell Polarity Genes in Human Colon Cancer. Exploratory

Research and Hypothesis in Medicine. 2018 Mar 21;3(1):14‐9.

71. Tan MC, Graham DY. Proton Pump Inhibitor Therapy After Helicobacter Pylori Eradication May

Increase the Risk of Gastric Cancer. BMJ Evid Based Med. 2018 Mar 29. pii: bmjebm‐2018‐

110935.

7 | P a g e

72. El‐Serag HB, Kao JY, Kanwal F, Gilger M, LoVecchio F, Moss SF, Crowe S, Elfant A, Haas T, Hapke

RJ, Graham DY. Houston Consensus Conference on Testing for Helicobacter pylori Infection in

the United States. Clin Gastroenterol Hepatol. 2018 Mar;16(7):992‐1002.e6.

73. VanWagner LB, Kanwal F. Hepatology in a Changing Health Care Landscape: A Call for Health

Services Research. Hepatology. 2018 Mar 14.

74. Hsu PI, Tsay FW, Graham DY, Tsai TJ, Tsai KW, Kao JY, Peng NJ, Kuo CH, Kao SS, Wang HM, Lin

TF, Wu DC; Taiwan Acid‐related Disease (TARD) Study Group. Equivalent Efficacies of Reverse

Hybrid and Bismuth Quadruple Therapies in Eradication of Helicobacter pylori Infection in a

Randomized Controlled Trial. Clin Gastroenterol Hepatol. 2018 Mar 31. pii: S1542‐

3565(18)30328‐8.

75. Alter H, Block T, Brown N, Brownstein A, Brosgart C, Chang KM, Chen PJ, Chisari FV, Cohen C, El‐

Serag H, Feld J. A research agenda for curing chronic hepatitis B virus infection. Hepatology.

2018 Mar;67(3):1127‐31.

76. Roy S, Esmaeilniakooshkghazi A, Patnaik S, Wang Y, George SP, Ahrorov A, Hou JK, Herron AJ,

Sesaki H, Khurana S. Villin‐1 and Gelsolin Regulate Changes in Actin Dynamics That Affect Cell

Survival Signaling Pathways and Intestinal Inflammation. Gastroenterology. 2018

Apr;154(5):1405‐1420.e2

77. Opekun AR, Gonzales SA, Al‐Saadi MA, Graham DY. Brief Report: Lactobacillus Bulgaricus GLB44

(Proviotic™) plus Esomeprazole for H. pylori Eradication: a Pilot Study. Helicobacter. 2018

Apr;23(2):e12476.

78. Biggerstaff KS, Frankfort BJ, Orengo‐Nania S, Garcia J, Chiao E, Kramer JR, White D. Validity of

code based algorithms to identify primary open angle glaucoma (POAG) in Veterans Affairs (VA)

administrative databases. Ophthalmic Epidemiol. 2018 Apr;25(2):162‐168.

79. Chew EY, Varghese BT, Sealock RJ. Pancreatic duct rendezvous with pancreatoscopy through the

minor papilla. VideoGIE. 2018 Apr 1;3(4):132‐4.

80. Khan A, Abdelfatah MM, Othman M. Screening and Surveillance of Barrett′ s Esophagus with

Confocal Endomicroscopy and Volumetric Laser Endoscopy. Techniques in Gastrointestinal

Endoscopy. 2018 Apr 25.

81. Wang Z, Graham DY, Khan A, Balakrishnan M, Abrams HR, El‐Serag HB, Thrift AP. Incidence of

gastric cancer in the USA during 1999 to 2013: a 50‐state analysis. Int J Epidemiol. 2018 Apr 16.

82. Khan MA, Hammad T, Khan Z, Lee W, Gaidhane M, Tyberg A, Kahaleh M. Endoscopic Versus

Percutaneous Management for Symptomatic Pancreatic Fluid Collections: A systematic Review

and Meta‐Analysis. Endosc Int Open. 2018 Apr;6(4):E474‐E483.

83. Chhatwal J, Chen Q, Ayer T, Bethea ED, Kanwal F, Kowdley KV, Wang X, Roberts MS, Gordon SC.

Hepatitis C virus re‐treatment in the era of direct‐acting antivirals: projections in the USA.

Alimentary pharmacology & therapeutics. 2018 Apr;47(7):1023‐31.

84. Chhatwal J, Kanwal F. Cost‐Effectiveness and Decision Analysis in Clinical Gastroenterology and

Hepatology: From Evidence to Informed Decision Making. Clin Gastroenterol Hepatol. 2018

Apr;16(4):459‐461.

85. Thakur ER, Shapiro J, Chan J, Lumley MA, Cully JA, Bradford A, El‐Serag HB. A Systematic Review

of the Effectiveness of Psychological Treatments for IBS in Gastroenterology Settings: Promising

but in Need of Further Study. Dig Dis Sci. 2018 May 10.

86. Mindikoglu AL, Opekun AR, Putluri N, Devaraj S, Sheikh‐Hamad D, Vierling JM, Goss JA, Rana A,

Sood GK, Jalal PK, Inker LA, Mohney RP, Tighiouart H, Christenson RH, Dowling TC, Weir MR,

8 | P a g e

Seliger SL, Hutson WR, Howell CD, Raufman JP, Magder LS, Coarfa C. A Unique Metabolomic

Signature Associated with Hepatorenal Dysfunction and Mortality in Cirrhosis. Transl Res. 2018

May;195:25‐47.

87. Sussman NL, Kelly JH. Extracorporeal cellular therapy (ELAD) in severe alcoholic hepatitis: A

multinational, prospective, controlled, randomized trial. Liver Transpl. 2018 May;24(5):711.

88. Zeuzem S, Serfaty L, Vierling J, Cheng W, George J, Sperl J, Strasser S, Kumada H, Hwang P,

Robertson M, Wahl J, Barr E, Talwani R, Platt H. The safety and efficacy of elbasvir and

grazoprevir in participants with hepatitis C virus genotype 1b infection. J Gastroenterol. 2018

May;53(5):679‐688.

89. Jones D, Manns MP, Terracciano L, Torbenson M, Vierling JM. Unmet Needs and New Models

for Future Trials in Autoimmune Hepatitis. Lancet Gastroenterol Hepatol. 2018 May;3(5):363‐

370.

90. Kramer JR, Puenpatom A, Erickson KF, Cao Y, Smith D, El‐Serag HB, Kanwal F. Real‐world

effectiveness of elbasvir/grazoprevir In HCV‐infected patients in the US veterans affairs

healthcare system. J Viral Hepat. 2018 May 31.

91. Hernaez R, Kanwal F, El‐Serag HB. HCC Screening is Associated with Survival Benefit in the in an

Silico but Needs Confirmation in an Vivo Analysis. Hepatology. 2018 May 10;68(1):7‐9.

92. Zou WY, El‐Serag HB, Sada YH, Temple SL, Sansgiry S, Kanwal F, Davila JA. Determinants and

Outcomes of Hospice Utilization Among Patients with Advance‐Staged Hepatocellular Carcinoma

in a Veteran Affairs Population. Digestive diseases and sciences. 2018 May 1;63(5):1173‐81.

93. Asrani SK, Kouznetsova M, Ogola G, Taylor T, Masica A, Pope B, Trotter J, Kamath P, Kanwal F.

Increasing Healthcare Burden of Chronic Liver Disease Compared to Other Chronic Diseases,

2004–2013. Gastroenterology. 2018 May 23.

94. Hsu YC, Ho HJ, Lee TY, Huang YT, Wu MS, Lin JT, Wu CY, El‐Serag HB. Temporal trend and risk

determinants of hepatocellular carcinoma in chronic hepatitis B patients on entecavir or

tenofovir. Journal of viral hepatitis. 2018 May;25(5):543‐51.

95. Qureshi WA. Office Management of Hemorrhoids Am J Gastroenterol. 2018 Jun;113(6):795‐798.

96. Shah R, Ho EY, Kramer JR, Richardson P, Sansgiry S, El‐Serag HB, Hou JK. Hepatitis B Virus

Screening and Reactivation in a National VA Cohort of Patients with Inflammatory Bowel Disease

Treated with Tumor Necrosis Factor Antagonists. Dig Dis Sci. 2018 Jun;63(6):1551‐1557.

97. Tan MC, Kanthasamy KA, Yeh AG, Kil D, Pompeii L, Yu X, El‐Serag HB, Thrift AP. Factors

Associated With Recurrence of Barrett's Esophagus After Radiofrequency Ablation. Clin

Gastroenterol Hepatol. 2018 Jun 11. pii: S1542‐3565(18)30595‐0.

98. Balakrishnan M, George R, Sharma A, Graham DY, Malaty HM. An Investigation into the Recent

Increase in Gastric Cancer in the USA. Dig Dis Sci. 2018 Jun;63(6):1613‐1619.

99. Frenette CT, Morelli G, Shiffman ML, Frederick RT, Rubin RA, Fallon MB, Cheng JT, Cave M,

Khaderi SA, Massoud O, Pyrsopoulos N, Park JS, Robinson JM, Yamashita M, Spada AP, Chan JL,

Hagerty DT. Emricasan Improves Liver Function in Patients With Cirrhosis and High Model for

End‐stage Liver Disease Scores Compared With Placebo. Clin Gastroenterol Hepatol. 2018 Jun

15. pii: S1542‐3565(18)30622‐0.

100. Tan MC, El‐Serag HB, Yu X, Thrift AP. Acid suppression medications reduce risk of oesophageal

adenocarcinoma in Barrett's oesophagus: a nested case‐control study in US male veterans.

Aliment Pharmacol Ther. 2018 Jun 29.

9 | P a g e

101. Wang Z, Shaheen NJ, Whiteman DC, Anderson LA, Vaughan TL, Corley DA, El‐Serag HB,

Rubenstein JH, Thrift AP. Helicobacter pylori Infection Is Associated With Reduced Risk of

Barrett's Esophagus: An Analysis of the Barrett's and Esophageal Adenocarcinoma Consortium.

Am J Gastroenterol. 2018 Jun 8.

102. Nguyen T, Khan A, Liu Y, El‐Serag HB, Thrift AP. The Association Between Statin Use After

Diagnosis and Mortality Risk in Patients With Esophageal Cancer: A Retrospective Cohort Study

of United States Veterans. Am J Gastroenterol. 2018 Jun 27.

103. Yeomans ND, Graham DY, Husni ME, Solomon DH, Stevens T, Vargo J, Wang Q, Wisniewski LM,

Wolski KE, Borer JS, Libby P, Lincoff AM, Lüscher TF, Bao W, Walker C, Nissen SE; PRECISION

investigators. Randomized Clinical Trial: Gastrointestinal Events in Arthritis Patients Treated with

Celecoxib, Ibuprofen or Naproxen in the PRECISION Trial. Aliment Pharmacol Ther. 2018

Jun;47(11):1453‐1463.

104. Hernaez R, El‐Serag HB. How we approach it: treatment options for hepatocellular carcinoma.

Am J Gastroenterol. 2018 Jun;113(6):791‐794.

105. Tapper EB, Kanwal F, Asrani SK, Ho C, Ovchinsky N, Poterucha J, Flores A, Smith JE, Ankoma‐Sey

V, Luxon B, Volk ML. Patient Reported Outcomes in Cirrhosis: A Scoping Review of the

Literature. Hepatology. 2018 Jun;67(6):2375‐2383.

106. Chhatwal J, Samur S, Bethea ED, Ayer T, Kanwal F, Hur C, Roberts MS, Terrault N, Chung RT.

Transplanting HCV‐positive livers into HCV‐negative patients with preemptive antiviral

treatment: A modeling study. Hepatology. 2018 Jun;67(6):2085‐2095.

107. Graham DY, Tansel A. Interchangeable use of proton pump inhibitors based on relative potency.

Clinical Gastroenterology and Hepatology. 2018 Jun 1;16(6):800‐8.

108. Yeomans ND, Graham DY. Editorial: gastrointestinal safety of COX‐2 selective and nonselective

NSAIDs‐the impact of the PRECISION trial. Authors' reply. Aliment Pharmacol Ther. 2018

Jun;47(11):1546‐1547.

109. Lee YC, Asaka M, Graham DY. Editorial: Helicobacter pylori and gastric cancer in Alaskan

Natives: Time to stop studying H. pylori and to eradicate it. Helicobacter. 2018

Jun;23(3):e12478.

10 | P a g e

DDW 2018 INVITED LECTURES DDW Hands On Hemorrhoid Therapies Course Waqar Qureshi

2018 AGA Postgraduate Course: From Abstract Reality Top 3 Clinical Articles Published in Gastroenterology and CGH In the Past Year Fasiha Kanwal

Advances in Regenerative Medicine for GI Disorders Differentiation of Human Pluripotent stem cells into intestinal tissue Noah Shroyer

Fellows Update: Are You a Second or Third Year Fellow Anorectal Diseases Waqar Qureshi

The Dr. Charles S. Lieber Lecture Mechanisms of Autoimmune Associated Liver Injury: How Are PBC, PSC and Autoimmune Hepatitis Alike and Different? John Vierling

ASGE Gastric Polyps Clark Hair

Fellows Update: Are You a Second or Third Year Fellow Questions and Answers Waqar Qureshi & Clark Hair

Management Strategies for AIH and Overlap Syndrome John Vierling

Celebrating the Successes of H. pylori Discovery Current Challenges in H. Pylori Eradication David Y. Graham

AGA Committee Sponsored Symposium: Difficult Conversations: Navigating People, Negotiations, Promotions and Complications WHEN PERSONALITIES CLASH: HOW TO HANDLE DIFFICULT COLLEAGUES Rhonda A. Cole

Management of Anorectal Disease for the Non‐Surgeon Managing Symptomatic Hemorrhoids in the Gastroenterology Office Waqar Qureshi

Incidental Liver Findings: When to Treat and How to Follow? The Hepatologist Perspective Norman Sussman

11 | P a g e

DDW 2018 ORAL PRESENTATIONS Research Forum Epigenetic Alterations in Mucosal Stem Cells in Pediatric Crohn’s Disease Wa Xian, Jeffrey S. Hyams, Frank D. McKeon, Francisco Sylvester, Khek‐Yu‐ Ho. Jason K. Hou

Clinical Symposium: NAFLD and NASH Effect of Metabolic Traits on the Risk of Cirrhosis and Hepatocellular Cancer (HCC) in Non‐Alcoholic Fatty Liver Disease (NAFLD) Fasiha Kanwal, Jennifer Kramer, Yamini Natarajan, Srikar Mapakshi, Liang Li, Jianliang Dai, Roxanne Desiderio, Peter Richardson, Hashem El‐Serag

Organoid Models of Gastrointestinal Disorders Two Dimensional Human Gastric Organoid Model of Helicobacter Pylori Infection Takahiro Uotani, Kosuke Murakami, Tomohisa Uchida, Shingo Tanaka, Hiroyuki Nagashima, Xi‐Lei Zeng, Junko Akada, Mary Estes, David Graham, Yoshio Yamaoka

Improved Outcomes from DAA Therapies Effectiveness and Utilization of Elbasvir/Grazoprevir in HCV Genotype 1 and 4 Infection in the Veteran Affairs Healthcare System in The Unites States Amy Puenpatom, Jennifer Kramer, Yumei Cao, Donna Smith, Hashem El‐Serag, Fasiha Kanwal

AGA Basic Science Plenary Epithelial‐Secreted WNT Ligands are Essential Drivers of Intestinal Stem Cell Response to Virus‐Induced Villus Damage Winnie Zou, Sarah Blutt, Xi‐Lei Zeng, Min‐Shan Chen, Yuan‐Hung Lo, David Castillo‐Azofeifa, Ophir Kein, Noah Shroyer, Mark Donowitz, Mary Estes

Research Forum‐ Limiting the Toxicity of Chemotherapy by Enhancing Regeneration of Intestinal Stem Cells. Min‐Shan Chen, Yuan‐Hung Lo, Noah Shroyer

Topic Forum‐ Endoscopic Enlightenment: Education and Training Use of Wearable Sensors to Assess Biomechanical Learning Patterns in Endoscopy Training Phillip Levine, Hadi Rahemi, Hyoki Lee, Hung Nguyen, Joseph Krill, Bijan Najafi, Kalpesh Patel

Topic Forum‐ Endoscopic Enlightenment: Education and Training Use of Wearable Sensors to Stress Response in Endoscopy Training Phillip Levine, Hadi Rahemi, Hung Nguyen, Hyoki Lee, Joseph Krill, Bijan Najafi, Kalpesh Patel

Esophageal, Gastric & Duodenal Disorders Distinguished Abstract Plenary: The Best of Barrett’s, EOE, GERD, H. Pylori Gastrointestinal events in arthritis patients at increased cardiovascular risk treated chronically with celecoxib, naproxen or ibuprofen: the precision randomized controlled trail Neville Yeomans, David Graham, M. Husni, Daniel Solomon, Tyler Stevens, John Vargo, Qiuqing Wang, Lisa Wisniewski, Katherine Wolski, Steven Nissen

12 | P a g e

Research Forum: Intestinal Epithelial Cell Biology Mucosal Stem Cell Heterogeneity in Pediatric Crohn’s Disease Frank McKeon, Wa Xian, Yutao Qi, Rahul Neupane, Shan Wang, Yusuke Yamamoto, Rajasekaran Mahalingam, Marcin Duleba, Christopher Crum, Francisco Sylvester, Jason Hou, Jeffrey Hyams, Khek‐Yu Ho

Nutrient Absorption and Regulation of Intake Amyloglucosidase Supplementation Corrects Small Intestinal Isomaltase Insufficiency in Symptomatic Patients Antone Opekun, Mustafa Abdulsada, Aileen DeJonge, Bruno Chumpitazi, David Graham

DDW 2018 POSTER PRESENTATIONS Title Session Authors

Familial Chylomicronemia Syndrome, A Possible Cause of Hypertriglyceridemia Induced Acute

Pancreatitis (HIAP) Clinical Acute Pancreatitis

Anam Khan, Talha Qureshi, Hiba Alie,

Chiemeziem Eke, Jianhua Andy Tau,

Mohamed Othman

Unilateral Versus Bilateral Meal Stents for Inoperable Malignant Hilar Biliary Strictures: A

Systematic Review and Meta‐Analysis ERCP 1

Tariq Hammad, Muhammad Ali Khan,

Yousef Abdel‐Aziz, Mohamad Imam,

Gyanprakash A. Ketwaroo, Stephen C.

Pappas

Readmission Rates following Gastroparesis‐related hospitalizations in a National US Cohort

Gastroparesis and Small Intestinal Dysmotility

Aylin Tansel, Marwan Abougergi, Fasiha

Kanwal, Hashem El‐Serag, Eamonn

Quigley

Surveillance‐Indication for Colonoscopy is Associated with Early Stage Colorectal Cancer

Among Patients with Inflammatory Bowel Disease IBD: Disease Complications

Brett Styskel, Valentine Millien, Nader

Massarweh, Jason Ken Hou

Microbiomic Profiling of Early‐Onset Colorectal Cancer

Microbiome and Cancer Iris Zhuang, Rajesh Shah, Patricia

Castro, Nadim Zarrin‐Khameh,

Benjamin L. Musher

EUS‐Guided Coil Application with Glue Injection for Gastric Variceal Obliteration is Associated with

Less Endoscopic Reintervention Compared to Glue Injection Alone

EUS 1 Joseph Krill, Mohamed Othman,

Khushboo Munot, Prasun Jalal, Kalpesh

Patel.

13 | P a g e

Helicobacter Pylori Antibiotic Resistance Patterns Among Non‐US Born and US‐Born Patients from an Ethnically Diverse Population Who Failed First‐Line

Therapy

Helicobacter pylori: Epidemiology, Diagnosis and

Outcomes

Jianhua Andy Tau, Jessica Lin

Genetic Ancestry and Risk of Hepatic Inflammation and Fibrosis in Patients with Chronic HCV

Hepatic Fibrosis, Diagnosis and Treatment

Aaron P. Thrift, Yanhong Liu, Spiridon

Tsavachidis, Donna L. White, Hashem B.

El‐Serag

The Prevalence and Characterization of Axial Spondyloarthritis Among Veterans with

Inflammatory Bowel Disease IBD: Epidemiology

Mark Salem, Jason Hou, Liron Caplan,

Hoda Malaty

Trainees in Gastroenterology and Maternal‐Fetal Medicine have More Pregnancy‐Related IBD

Knowledge Compared with Trainees in Internal Medicine or Obstetrics‐Gynecology

Medical Education

Steven Stanek, Shannon Chang, Richa

Shukla, Neilanjan Nandi, Robin

Rothstein, Frank Friedenberg, Adam

Ehrlich

The Prevalence of Exocrine Pancreatic Insufficiency in Patients with Fatty Pancreas on Endoscopic

Ultrasound EUS 2

Joseph Krill, David Szafron, Sherif

Elhanafi, Kalpesh Patel, Isaac Raijman,

William Fisher, Mohamed Othman

Time for Changing of Guard: From Minimally Invasive Surgery to Endoscopic Drainage for

Management of Walled‐Off Pancreatic Necrosis EUS 2

Muhammad ali Khan, Michael Kahaleh,

Amy Tyberg, Zubair Khan, Tariq

Hammad, Aijaz Sofi, Shreesh Shrestha,

Mohammad K. ismail, Claudio

Tombazzi, Todd H. Baron

Impact of Acid‐Reducing Agents on Effectiveness of Elbasvir/Grazoprevir in a US Veterans Affairs Population with Hepatitis C Virus Infection

HCV Linkage to Care and Therapeutics

Jennifer Kramer, Amy Puenpatom,

Yumei Cao, Donna Smith, Hashem El‐

Serag, Fasiha Kanwal

The Association of Joint Extra‐Intestinal Manifestations in Patients with Inflammatory Bowel Disease on Quality of Life: A Prospective

Multi‐Center Study

IBD: Quality of Life/Psychosocial Care

Mark Salem, Hoda M. Malaty, Linda A.

Feagins, Ann DeBourcy Flynn, Michael

Yao, Jessica B. Johnson, Liron Caplan,

Jason Ken Hou

Sustainable Improvements in Urgent Care Access and Outcomes for Patients with Inflammatory Bowel Disease Through Implementation of an

Urgent Access Toolkit

Practice Management/Quality of Care/ Quality Assurance

Jason Hou, Iliana Gonzalez, Ang Xu,

Julie Weatherly, Richa Shukla, Joseph

Sellin, Guillermina Cruz, Damara Crate,

Kelly McCutcheon Adams, Alandra

Weaver, Gil Melmed, Corey Siegel

Reduction in the Prevalence of Anemia among Patients with Inflammatory Bowel Disease after Implementation of the Anemia Care Pathway


Jason Hou, Ruifei Wang, Sunina

Nathoo, Julie Weatherly, Joseph Sellin,

Richa Shukla, Guillermina Cruz, Ridhima

Oberai, Corey Siegel, Gil Melmed

Health Maintenance in Inflammatory Bowel Disease: Impact of Insurance Status


Krishna Sajja, Upasana Banerjee, Sidra

Ahsan, Richa Shukla, Guillermina Cruz,

Manreet Kaur

Prevalence and Risk Factors for Male Sexual Dysfunction in a Prospective Multicenter VA Inflammatory Bowel Disease Population

Quality of Life/Psychosocial Care

Jill Gaidos, Katrina Herbst, Jenny Dave,

Michael Yao, Jason Ken Hou, Andrew

David Smith, Linda A. Feagins

14 | P a g e

*Poster of Distinction Prevalence of Barrett's Esophageal

Adenocarcinoma: A Systematic Review and Meta‐Analysis

Barrett's Esophagus: Diagnosis, Management and

Surveillance

Mimi Tan, Nabil Mansour, Donna

White, Hashem El‐Serag, Aaron Thrift

Using Natural Language Processing to Accurately Identify Dysplasia in Pathology Reports for Patients

with Barrett’s Esophagus

Barrett’s Esophagus: Diagnosis, Management and

Surveillance

Aaron P. Thrift, Yamini Natarajan, Nabil

Mansour, Jingqi Wang, Hua Xu, Jason K.

Hou, Hashem B. El‐Serag

Prior Diagnosis of Barrett’s Esophagus in Patients with Esophageal Adenocarcinoma is Infrequent,

but Associated with Improved Survival


Surveillance

Aaron P. Thrift, Theresa Nguyen

Wenker, Mimi Tan, Yan Liu, Hashem B.

El‐Serag

Ultrashort Segment Barrett’s May Not Be As Benign As Commonly Thought


Surveillance

Khushboo Munot, Rhonda Cole, Maria

Velez, Clark Hair, Gyanprakash

Ketwaroo

Improved Treatment Delivery and Overall Survival Associated with Multidisciplinary Tumor Board

Evaluation of Patients with Advanced Hepatocellular Carcinoma

Clinical Liver Cancer

Winnie Zou, Sarah Temple, Yvonne

Sada, Hashem El‐Serag, Sarah May,

Fasiha Kanwal, Peter Richardson, Daniel

Anaya, Jessica Davila

Risk of Hepatocellular Cancer Recurrence in HCV Patients treated with Direct‐Acting Agents in a

United States Veteran Population Clinical Liver Cancer

Winnie Zou, Kati Choi, Jennifer Kramer,

Xian Yu, Yumei Cao, Hashem El‐Serag,

Fasiha Kanwal

Association Between Body Mass Index and Composition of Mucosa Associated Intestinal

Microbiota in Healthy Individuals

Clinical and Translational: Microbiome and Microbial

Diseases in the Gastrointestinal Tract

Themistoklis Kourkoumpetis, Nadim J.

Ajami, Diane Hutchinson, Liang Chen,

Sharon Mondrik‐Mendez, Donna

White, Rhonda A. Cole, David Y.

Graham, Antone R. Opekun, Hashem B.

El‐Serag, Joseph F. Petrosino, Li Jiao

Endoscopy Report Card Leads to Improved Adenoma Detection Rates during Fellowship

Training Clinical Practice I

Sunina Nathoo, Loan Ho, Milena Gould

Suarez, and RJ Sealock

Evaluation of Aspiration Fluid Cytology as an Adjunct with Single Operator Cholangioscopy and Targeted Biopsy to Improve the Diagnostic Yield in

Indeterminate Biliary Strictures

ERCP 2

Khushboo Munot, Vinshi Khan,

Cassandra Gandle, Marwah Shahid, Yan

Liu, Kalpesh Patel, Isaac Raijman,

Mohamed Othman

Screening and Surveillance for Barrett’s Esophagus in Veterans Subsequently Diagnosed with

Esophageal Adenocarcinoma

Esophageal and Junctional Neoplasms:

Precursor Lesions, Biology, Diagnosis and Clinical

Therapeutics II

Tariq Hammad, Aaron P. Thrift, Hashem

B. El‐Serag, Nisreen S. Husain

Lactobacillus Reuteri and a PPI Alone Provide Approximately at 12% Additive increase in H. Pylori

Eradication

Helicobacter pylori: Treatment and Antimicrobial

Resistance

Maria Pina Dore, Ruggero Francavilla,

Stefano Bibbò, David Yates Graham

15 | P a g e

Risk of Bias in Systematic Reviews of Existing Systematic Reviews and Meta‐Analysis of Probiotic

Use in Irritable Bowel Syndrome

Irritable Bowel Syndrome: Clinical

Jordan Shapiro, Jessica Bernica,

Hashem B. El‐Serag, Ruben Hernaez

Impact of Implementation of the Anemia Care Pathway for inflammatory Bowel Disease on the Iron Treatment Patterns and Anemia Prevalence in

a Managed‐Care Setting

Process Improvement Talha Qureshi, Thien‐Bao Peter Nguyen,

Diana Willis, Rajesh Shah, Jason Ken

Hou

Expression of Pattern Recognition Receptor Pathway Genes and Colorectal Neoplasms

Inflammation and GI Cancers

Themistoklis Kourkoumpetis, Liang

Chen, Qainzing Mo, Fengju Chen, Sarah

Plew, Ashley Johnson, Preksha, Shah,

Kathryn Royse, Donna White, Rhonda

A. Cole, David Y. Graham, Clark Hair,

Jason K. Hou, Nisreen S. Husain, M.

Ellionore Jarbrink‐Sehgal, Fasiha

Kanwal, Gyanprakash A. Ketwaroo,

Daniel Rosen, Rajesh Shah, Maria E.

Velez, Melissa Bondy, Hashem B. El‐

Serag, Li Jiao

One‐Carbon Metabolism Nutrients in Relation to Mucosa‐associated Gut Microbiome in Healthy

Individuals

Microbiome and Microbial Diseases of the GI Tract

Shawn Gurwara, Nadim J. Ajami, Diane

Hutchinson, Liang Chen, David Graham,

Sarah Plew, Ashley Johnson, Preksha

Shah, Kathryn Royse, Donna L. White,

Jennifer Kramer, Themistoklis

Kourkoumpetis, Rhonda Cole, Clark

Hair, Jason Hou, Nisreen Husain, Maria

Jarbrink‐Sehgal, Fasiha Kanwal,

Gyanprakash Ketwaroo, Rajesh Shah,

Maria Velez, Melissa L. Bondy, Susan

Hilsenbeck, Margaret R. Spitz, Hashem

B. El‐Serag, Joseph F. Petrosino, Li Jiao

16 | P a g e

PRESS Kanwal: Gastroenterology. Direct‐acting antivirals reduce liver cancer risk.

http://www.medicaleconomics.com/medical‐economics/news/direct‐acting‐antivirals‐reduce‐liver‐

cancer‐risk (Jun 2017) a

Qureshi: World Congress of Gastroenterology at ACG 2017 meeting. “Office Management of Acute

Thrombosed Hemorrhoids in a Pregnant Patient.” (Jul 2017) a

Anandasabapathy: The Hindu. “Emergency smart pods for India a possibility.”

https://www.thehindu.com/news/cities/chennai/emergency‐smart‐pods‐for‐india‐a‐possibility/ (Oct

2017) a

Hou: GI & Hepatology News. “One‐Day Behavioral Therapy for IBD Patients.”

https://www.mdedge.com/gihepnews/clinical‐edge/summary/ibd‐intestinal‐disorders/one‐day‐

behavioral‐therapy‐ibd‐patients (Oct 2017) a

El‐Serag: KVEO’s RGVproud. “October Is Liver Cancer Awareness Month.”

https://www.kveo.com/news/local‐news/october‐is‐liver‐cancer‐awareness‐month/ (Nov 2017) a

Shukla: BCM’s Momentum Series. “Healthy Habits: Planning meals, setting exercise goals key for Dr.

Richa Shukla.” https://blogs.bcm.edu/2017/11/13/healthy‐habits‐dr‐richa‐shukla/(Nov 2017) a

Jiao: American Institute for Cancer’s Cancer Research Update. “Low‐Fat Diet Effective in Reducing

Pancreatic Cancer Risk Among Overweight Women.” http://www.aicr.org/cancer‐research‐

update/2017/11_29/cru‐low‐fat‐diet‐pancreatic‐cancer.html (Dec 2017) a

Kanwal: MD Magazine. “Researchers May Have Confirmed Whether HCV Treatment Poses Liver

Cancer Risk .” https://www.mdmag.com/medical‐news/researchers‐may‐have‐confirmed‐whether‐

hcv‐treatment‐poses‐liver‐cancer‐risk (Dec 2017) a

Mittal: Healio. “10 reports from 2017 on liver cancer incidence rates, major risk factors.”

https://www.healio.com/hepatology/oncology/news/online (Jan 2018) a

Estes and Shroyer: BCM’s Cell Reports. Researchers gain insight into how the intestine repairs itself.

https://www.bcm.edu/news/molecular‐virology‐and‐microbiology/how‐the‐intestine‐repairs‐itself

(Jan 2018) a

Hussain: National VA Transplant Conference. (Feb 2018) a

Chan: Clinical Gastroenterology and Hepatology. “Physician Burnout: The Hidden Health Care Crisis.”

https://www.cghjournal.org/article/S1542‐3565(17)30790‐5/fulltext (Mar 2018)

Graham: first annual Stefan S. Nicolau Lecture‐‐ Carol Davila University of Medicine in Bucharest,

Romania. “Helicobacter pylori: a bacterial cause of gastric cancer.” (Mar 2018) a

Hernaez: VA Liver Cancer Team Educational Seminar Series. “Curative and Palliative Therapies for

HCC.” (Apr 2018) a

17 | P a g e

Estes: Baylor’s From The Labs. “Type of injury matters, when healing the small intestine.”

https://blogs.bcm.edu/2018/03/20/type‐of‐injury‐matters‐when‐healing‐the‐small‐intestine/ (Mar

2018) a

Qureshi: BCM DocTalk. “Colorectal Cancer Awareness Month.” (Mar 2018) a

Graham: Fifth Annual Ertan Lectureship at UT McGovern Medical School. “Helicobacter Pylori as a

Bacterial Cause of Gastric Cancer.” (Apr 2018)

Hou: Time. “You Asked: What Is Inflammation, And Why Should I Care About It?”

http://time.com/5235368/what‐is‐inflammation/ (Apr 2018)

Graham: Gastrointestinal Endoscopy and Video GIE. "Meet the Master."

https://youtu.be/_VoRLbLt6PU (May 2018)

Bradford: The Wall Street Journal. “A Surprise Medical Solution: Hypnosis.”

https://www.wsj.com/articles/a‐surprise‐medical‐solution‐hypnosis‐1525698883 (May 2018)

Vierling: Dr. Charles S. Lieber Lecture at DDW 2018. “Mechanisms of Autoimmune‐Associated Liver

Injury – How Are PBC, PSC and Autoimmune Hepatitis Alike and Different?” (Jun 2018)

GRANTS Anandasabapathy MPI: High Resolution Microendoscopy for the Management of Esophageal Neoplasia. National Cancer

Institute (NCI); R01‐CA181275. 9/1/2017‐8/31/2018

A Low‐Cost Tethered Capsule Endoscope for Esophageal Cancer Screening. National Institutes of

Health (NIH); R21‐EB023431. 1/1/2017‐12/31/2018

NCE 3 – EZPOD: Enhanced Zero‐Impact, Emergency Smart Pod. Paul G. Allen Family Foundation;

11965. 5/2/2018‐10/31/2018

Balakrishnan GS1944: A Phase 3 Randomized Double‐Blind, Placebo‐Controlled Study Evaluating the Safety and

Efficacy of Selonsertib in Subjects with Compensated Cirrhosis Due to Nonalcoholic Steatohepatitis

(NASH). Gilead Sciences, Inc. 2019

INT 747‐304: A Phase 3, Double‐Blind, Randomized, Placebo‐Controlled, Multicenter Study to

Evaluate the Efficacy and Safety of Obeticholic Acid in Subjects with Compensated Cirrhosis due to

Nonalcoholic Steatohepatitis. Intercept Pharmaceuticals. 2019

Criss The Role of Homeobox Genes in Conferring Intestinal Regional Identity. Howard Hughes Medical

Institute; 59008473. 9/1/2017‐8/31/2018

18 | P a g e

El‐Serag The Texas Hepatocellular Carcinoma Consortium (THCCC). Cancer Prevention & Research Institute of

Texas (CPRIT). RP150587. 6/1/2018‐5/31/2019

Effect of Aspirin on Biomarkers of Barrett’s Esophagus after Successful Eradication of Barrett’s

Esophagus with Radiofrequency Ablation. National Cancer Institute (NCI); HHSN‐

26120120003414929. 6/15/2016‐6/14/2019

Center of Gastrointestinal Infection and Injury. National Institute of Diabetes and Digestive and

Kidney Diseases (NIDDK); P30‐DK056338. 3/1/2018‐2/28/2019

Research Training in Gastroenterology. National Institute of Diabetes and Digestive and Kidney

Diseases (NIDDK); T32‐DK083266. 2/1/2018‐1/31/2019

A Lab based Algorithm for HCC Surveillance in Patients with Cirrhosis. National Institutes of Health

(NIH); R01‐CA190776. 4/1/2018‐1/31/2019

Finnell Folate Pathway Neural Tube Defects. March of Dimes; 6‐FY16‐169. 6/1/2018‐5/31/2019

Intervention Strategies for Non‐Folate Responsive Neural Tube Defects. National Institute of Child

Health and Human Development (NICHD); R01‐HD083809. 2/1/2019‐8/1/31/2019

Folic Acid, Parental Mutation Rates and the Risk for Neural Tube Defects. National Institute of Child

Health and Human Development (NICHD); R01‐HD081216. 7/1/2018‐6/30/2019

Hou Patient‐Centered Comparative Effectiveness of Colorectal Cancer Surveillance in IBD. AHCPR‐Agency

for Healthcare Research and Quality (AHRQ); K08‐HS024122. 8/1/2018‐7/31/2019

Advanced IBD Fellowship; Balor College of Medicine. Pfizer, Inc; Pfizer Fellowship. 7/1/2018‐

6/30/2019

A Multicenter, Randomized, Double‐Blind, Placebo‐Controlled Study to Evaluated the Safety and

Efficacy of ABT‐494 For Indication and Maintenance Therapy in subjects with Moderately to Severely

Active Ulcerative Colitis. Abbvie Inc. 2019

A Multi Center Open‐Label Extension Study to Assess the Safety and Tolerability of LYC‐30937‐EC in

Subjects with Active Ulcerative Colitis. Lycera Corp. 2019

Kanwal A Personalized Surveillance program for Hepatocellular Carcinoma. American Cancer Society; RSG‐17‐

022‐01‐CPPB. 7/1/2018‐6/30/2019

Cirrhosis Quality Collaborative. American Association for the Study of Liver Disease. 9/1/2018‐8/31/2021

Patient Centered Care for Individuals with Advanced Liver Disease. HSR&D IIR 16‐075; I01 HX‐002204‐01. 4/01/18‐3/31/21

19 | P a g e

Kaur A Phase 2B, Randomized, Double‐Blind, Placebo‐controlled, Parallel‐Group, Multicenter Protocol to

Evaluate the Safety and Efficacy of JNJ‐64304500 in Subjects with Moderately to Severely Active

Crohn’s Disease. Janssen Research & Development, LLC. 2019

A Phase 4 Open‐Label Study to Evaluate Vendolizumab IV Dose Optimization on Treatment Outcomes

in Nonresponses with Moderately to Severely Active Ulcerative Colitis (Enterpret). Takeda Global

Research & Development Center, Inc. 2019

Lo Transcription Factors in Intestinal Differentiation and Cancer. sNational Cancer Institute (NCI); F99‐

CA212443. 9/21/2016‐8/31/2018

Mittal Prevent HCC – By Screening, Vaccination and Treatment of Viral Hepatitis. Cancer Prevention &

Research Institute of Texas (CPRIT); PP160089. 8/31/2017‐8/30/2018

Opekun QA Purity, Activity and Ancillary Testing of Commercially Available Gras‐Listed Enzymes (Does Not

Include Human or Animal Studies). Association in Transformational Oncology Management (ATOM);

Testing Agreement. 3/1/2016‐3/11/2019

Othman Population Screening for Familial Chylomicronemia Syndrome (“FCS”). Akcea Therapeutics, Inc.

3/13/2018‐3/12/2019

Phase IIA Trial Evaluating the Safety of Intratumoral Injection of Nanopac in Subjects with Locally

Advanced Pancreatic Adenocarcinoma. US Biotest, Inc. 2019.

A Trial Evaluating Escalating Doses and the Safety of Intracystic Injection of Nanopac in Subjects with

Mucinous Cystic Pancreatic Neoplasms. US Biotest, Inc. 2019.

Shroyer MPI‐Investigation of Regional Identity in Human Intestinal Stem Cells—Subcontract. National

Institutes of Health (NIH); U01‐DK103117. 9/1/2017‐8/31/2018

Nutrigenomics of Intestinal Vitamin D Action. National Institutes of Health (NIH); R01‐DK112365.

4/1/2018‐3/31/2019

Thrift Prevent HCC – By Screening Vaccination and Treatment of Viral Hepatitis. Cancer Prevention &

Research Institute of Texas (CPRIT); PP160089. 8/31/2017‐8/30/2018

General Internal Medicine


SGIM

Hamilton, W (PI): Houston Home-Based Integrated Intervention Targeting Better Asthma Control for African Americans. Patient centered outcomes research institute (PCORI). AS-1308-05887, 1/1/2014- 6/30/2018.

Hamilton, W (PI): Environmental Exposures, Health and Resilience before and after Hurricane Harvey in a Houston-Area Cohort of African-American Adults with Poorly Controlled Asthma. National Institute of Environmental Health Sciences (NIEHS), 1R21-ES029690-01 01, 2/1/2018-1/31/2010.

Hamilton, W (PI): Pathways Linking Neighborhood Environments to Activity Behaviors. American cancer society. MRSG13145-01. Subcontract with University of Texas MD Anderson Cancer Center. 9/1/2014-6/30/2018

Hamilton, W (PI): Protecting the Health of Houstonians and Texas Gulf coast residents. Philanthropic gift from Jacob and Terese Hershey Foundation. 1/15/2018-1/14/2019

Oluyomi, A (PI): Hurricane Harvey DR2: Individual chemical exposure assessments. National Institute of Environmental Health Sciences (NIEHS). Subcontract with Oregan state university. 1/2/2018-1/1/2020

Vaughan, E (PI): Technology to improve the health of resource poor Hispanics with diabetes. National Institutes of Health, 1K23-DK110341-01A1, 4/1/2017-3/31/2022.

Lescinskas, E (Co-I): Identifying and reducing catheter related complications. Dept. of Veteran’s affairs,

VA251-15-C-0187, 7/1/2015-5/31/2018.

Sargsyan, Z and Sherman, S (Co-PI): The Academy of Resident-Educators Lab: An Educational Scholarship Elective from Alliance for Academic Internal Medicine (AAIM). 7/9/2018-6/4/2019

GRANTS

Books & Book Chapters

Dr. Lee Lu, associate professor, General Internal Medicine – Harris Health System, is an editor on a recently released book, Leading an Academic Medical Practice. Dr. Lu led the group of Society of General Internal Medicine academic leaders to produce the book, which discusses the key elements on how to manage a medical clinic with learners.

Dr. Wayne Shandera, assistant professor of General Internal Medicine is the editor of the recently published book entitled Sub-Specialty Care of HIV-Infected Patients. Nova Scientific, 2018. In the same book he also wrote a chapter “ General medicine consultation for the HIV

infected patient”.

Dr. Wayne Shandera, assistant professor of General Internal Medicine is co-author of chapter “ Viral and Rickettsial Diseases”, in Mcphee SJ, Papadakis et al, 2017 edition: Current

Medical Diagnosis and Treatment, New York, NY : McGraw Hill.

Dr. David Hilmers, professor of General Internal Medicine, is author of two chapters in Feigin and Cherry’s Pediatric Infectious Disease 8th edition, which came out in February 2018.

He authored chapter 145, “Nonveneral Treponematoses” and co-author for chapter 187, “Filoviral Hemorrhagic Fevers: Marburg and Ebola Virus Fevers”.

https://www.us.elsevierhealth.com/feigin-and-cherrys-textbook-of-pediatric-infectious-diseases-9780323376921.html

Peer-reviewed publications

Agrawal A. X + Y Scheduling Models in Internal Medicine Residency Programs: A National Survey of Program Directors’ Perspectives. American Journal of Medicine. 2018 Jan;131(1):107-114 Petrilli C, Saint S, Jennings J, Caruso A, et al. Understanding patient preferences for physician attire: a cross sectional observation study of 10 academic medical centers in the USA. BMJ Open. 2018 May 29; 8(5):e021239 Candler S. We didn’t get cold feet. Annals of Internal Medicine. Shunk R, Candler S, Lieblow M. Will graduate medical education at VA hospitals survive the choice act? SGIM forum. 2018 April; 4 (4) Robinson C, Fisher M, Lane S, Candler S. Creating a national health policy and advocacy curriculum. SGIM Forum. 2018 June;41(6):1-2

SCHOLARLY ACTIVITY

http://www.springer.com/us/book/9783319682662



De La Cruz A. Kappa opioid receptor antagonism: Are opioids the answer for treatment resistant depression? Ment Health Clin [Internet] 2018;8(4):175-83. DOI: 10.9740/mhc.2018.07.175. Fisher J, Bonomi A. Firearm Surrender Laws: Prompting Promise for Women’s Health. Ann Int Med. 2017;167(8):591-2. Angeles-Agdeppa I, Magsadia CR, Aaron GJ, Lloyd BB, Hilmers DC, Bhutta ZA. A Micronutrient Fortified Beverage Given at Different Dosing Frequencies Had Limited Impact on Anemia and Micronutrient Status in Filipino Schoolchildren. Nutrients. 2017 Sep 12;9(9). pii: E1002. doi: 10.3390/nu9091002. Horstman M, Spiegelman A, Naik A, Trautner B. Urine Culture on Admission Impacts Antibiotic Use and Length of Stay: A Retrospective Cohort Study. Infect Control Hosp Epidemiol. 2018 Mar 27 [Epub ahead of print] Horstman M, Spiegelman A, Naik A, Trautner B. Reply to Puig-Asensio et al. Clinical Infectious Diseases, Volume 66, Issue 10, 2 May 2018, Pages 1647–1648, https://doi.org/10.1093/cid/cix1100 Naik A, Horstman M, Kunik M et al. Wearable sensors and the assesment of fraility among vulnerable adults: an observational cohort study. Sensors. 2018 April-26;18(5) Hyman D. Hypertension: Does Polypharmacy Lead to Nonadherence or Nonadherence to Polypharmacy? Hypertension. 2017. Jun; 69(6): 1017-1018.

Hyman D, Pavlik V. Controlling Hypertension: We Have the Tools-We Just Need to Use Them. J Gen Intern Med. 2017. Aug; 32(8):860-862. Meyer A, Khanna A, Desai S, Kusnoor A, Singh H. Evaluating a mobile application for improving clinical laboratory test ordering and diagnosis. Journal of the American Medical Informatics Association, Volume 25, Issue 7, 1 July 2018, Pages 841–847, https://doi.org/10.1093/jamia/ocy026 Lin D, Shah C, Campbell S, Bates J, Lescinskas E. Getting it RITE: Impact of a dedicated hospital medicine curriculum for residents. South Med J. 2018 Jan;111(1):30-34. Lu L, Hyman D. –Cefazolin Related Acute Interstitial Nephritis with Associated Nephrotic-Range Proteinuria: A Case Report. Drug Saf - Case Reports. 2018;5(1):16. doi:10.1007/s40800-018-0080-5 Mbue J et al. HIV Related Refractory Hodgkin Lymphoma: A Case Report of Complete Response to Nivolumab. Clinical Lymphoma, Myeloma and Leukemia.

https://doi.org/10.1093/cid/cix1100

Murphy D, Meyer A, Vaghani V, Russo E, Wei L, Singh H, et al. Electronic triggers to identify delays in follow-up of mammography: Harnessing the power of big data in health care. J Am Coll Radiol. 2018 Feb;15(2):287-295 Murphy D, Meyer A, Vaghani V, Wei L, Singh H, et al.Development and validation of trigger algorithms to identify delays in diagnostic evaluation of gastroenterological cancer. Clin Gastroent Hepat: 2017 Aug 10: in press. Salcicicioli K, Ermis P, Oluyomi A et al. Geographic disparities in access to care for adults congenital heart disease patients in the United States. J AM Coll Cardiolo. 2018 Mar 10;71(11);A558 Schmidt M. Forgiveness. Literary AMWA. 2017 Dec 30 [Online] Stewart D, Dang B, Trautner B, Cai C et al. Assesing residents knowledge of patient satisfaction: a cross sectional study at a large academic medical center. BMJ Open. 2017 Aug 21;7(8) Gregory M, Bryan J, Hysong S, Stewart D, Woodard L, Naik A, Godwin K, et al. Evaluation of a Distance Learning Curriculum for Interprofessional Quality Improvement Leaders. Am J Med Qual. 2018 Mar 26. Epub ahead of print Tschaepe M. Representations of patients experiences of autonomy in graphic medicine. AMA J Ethics, 2018 Feb 1;20(1):122-129 Moreira T, Hernandez D, Scott C, Murillo R, Vaughan E. "Susto, Coraje y Fatlismo”: Cultural Bound beliefs and the treatment of diabetes among socio-economically disadvantaged hispanics. American Journal of Lifestyle Medicine. 12(1):30-33. Vaughan E, Moreno J, Hyman D, Chen T, Foreyt J Efficacy of oral versus insulin therapy for individuals with newly diagnosed type 2 diabetes in low-income settings” in Archives of General Internal Medicine 1(2). 17-22. Vaughan E. Integrating CHWs as part of the team leading diabetes group visits: A randomized controlled feasibility study. The Diabetes Educator. 43:6. 589-599, Vaughan E. Dual therapy appears superior to monotherapy for low-income individuals with newly diagnosed type 2 diabetes. Journal of Primary Care and Community Health. Article first published online: December 7, 2017, ). Vaughan E. Impact of Child Summertime Obesity Prevention Interventions on BMI and Weight-Related Behaviors: A Systematic Review and Meta-Analysis Protocol. BMJ Open. 7:10. Vaughan E. Addressing Outcomes Expectancies in Behavior Change. American Journal of Lifestyle Medicine. 11:6. 430-432. Wilmer S. Assessment of an Innovative Medication Adherence Training Exercise in an Interprofessional Training Program, Journal of Health and Interprofessional Practice

Abstracts/Presentations/workshops

Dr. Sabina Lee, associate professor and Dr. Sarah Candler, assistant professor, General Internal Medicine – MEDVAMC, recently participated and/or presented at the The Texas Chapter of the American College of Physicians annual conference in San Antonio. Dr. Lee moderated the session presented by Dr. Hashem El-Serag, professor, Gastroenterology and Hepatology, and chairman, Department of Medicine, “GI Multiple Small Feedings of the Mind”. Dr. Ricardo Nuila, served on a panel in the “Reporting Health” session at the Healthier Texas Summit in Austin on November 7. This meeting is organized by the University of Texas System and convenes thought leaders and practitioners statewide to discuss innovations and trends in community and public health. Dr. Anoop Agrawal, assistant professor, General Internal Medicine, presented “Integration of Apps into Internal Medicine Residency curriculums: A survey of IM program directors” was presented at Association of Program Director’s for Internal Medicine (APDIM) in San Antonio on March 19, 2018. Dr. Meroe Morse, assistant professor, General Internal Medicine Presented at ACGME Florida (March 2018) Workshop on Resident Wellness Initiative with Stacey Rose, MD. Dr. Wayne Shandera presented his abstract titled “The relationship between music and medicine as evidenced in the medical literature” was accepted in annual meeting, European Society for the Philosophy of Medicine and Health Care. Dr. Stephanie Sherman, assistant professor General Internal Medicine presented the following: The Academy of Resident Educators Lab: A Medical Education Research Curriculum-oral Presentation at Southern SGIM Conference, Feb 2018, New Orleans, LA, Internal medicine upper level boot camp: baseline survey and pilot curriculum- poster presentation at National SGIM Conference, April 2018, Denver, CO and Make Cognitive Errors in an App, Not on the Wards: Online Case Simulations to Enhance Diagnostic Reasoning at SGIM National Conference. Denver, CO. 4/2018. Dr. Anita Kusnoor was a co-presenter of Streptococcus constellatus brain abscesses masquerading as metastases. Presented at the Texas Chapter Annual Meeting of the American College of Physicians, San Antonio, November 11, 2017 and in National Meeting of the American College of Physicians, New Orleans, LA, April 21, 2018. She also presented It’s my fault!” Disclosing Medical Error; Assuming Blame in Interprofessional Education along with Dr. Nadia Ismail, associate professor, General Internal Medicineat the TEACH-S Conference, Houston, TX, May 11, 2018. Dr. Michelle Sibille, Instructor, General Internal Medicine- VAMC presenting both a poster and a presentation titled "Morbidity and Mortality Conference: An Innovative Strategy to Teach

Quality and Safety in the Outpatient Setting" at the AAMC Integrating Quality Conference, June 7-8. 2018. Her co-authors were Dr. Frene Lacour-Chestnut, Dr. Molly Horstman, assistant professor of General Internal Medicine-VAMC and Dr. Diana Stewart, assistant professor of General Internal Medicine-VAMC Arunthamakun J, Choi K, Amenta E, Kees J, Ritter C. Stranger Things: The connection between minimal change disease and childhood asbestos exposure. - Best Clinical Vignettes Top 8 Finalist Liebler H, Lim J, Sachs S, Sargsyan Z, Sherman S. Internal Medicine Upper Level Boot Camp: Baseline survey. SGIM, Denver, CO. 2018. Sargsyan, Z, Nguyen T, Larsen D Kulkarni S. The effect of time compressed playback of audio lectures on learning and retention: A pilot study. SGIM, Denver, CO. 2018 Amidi O, Averyt A, Shah C. The case of acidotic stabbing victim: Just follow your nose. SGIM. Denver, CO. 2018 Mammen A, Sherman S, Arnell M. A case of non-occlusive acute gastric ischemia from hypotension during dialysis, SHM, Orlando, FL. 2018 Kapuria M, Lin D. Not all psychosis is purely psychiatric- A case of Anti-NMDAR Encephalitis. SHM. Orlando, FL. 2018 Bass, M, Lim J, Sargsyan Z. Left and right you see Staph: Find the source and trace the path. SHM. Orlando, FL. 2018. Olmstead R, Sargsyan Z. Levofloxacin induced myoclonus. SHM. Orlando, FL. 2018 Olmstead R, Laeeq R, Katsnelson M, Hammoud N, Chu D, Lin D, Scally K. Renal masses and Cauda Equina syndrome- a rare presentation of T-cell Histocyte- Rich large B Cell lymphoma. SHM, Orlando, FL Dr. Joslyn Fisher co-presented a poster on 360 Degree Involvement: Addressing Domestic and Sexual Violence Across Academic Health Centers. National Conference on Health and Domestic Violence, San Francisco, September 2017.

Dr. David Hilmers, professor, General Internal Medicine, presented “Medical Care of

Hepatitis B Infected Patients in North Korea” at the Japanese-Korean Medical Association Annual Meeting, Kobe, Japan, November 2017.

Dr. Sarah Candler, assistant professor, General Internal Medicine – MEDVAMC, presented in a workshop at the Society of General Internal Medicine 2018 Southern Regional Meeting in New Orleans on Feb. 23, with several colleagues as part of the Leadership in Health Policy program. Her presentation was titled “It’s like a John Deere Tractor: Finding Common Ground in Health Advocacy in the South.” In addition, she also led a workshop called “Having Difficult

Conversations as a Leader” at the American College of Physicians’ Board of Governors meeting

in Montreal, Canada.

and pilot curriculum. SGIM 2018 National Meeting

Section-based Awards At the Section of General Internal Medicine Annual Retreat held at McNair campus on May 9, the following awards were presented:

AWARDS, HONORS, & OTHER ACCOLADES

Dr. Cara Foldes: Outpatient Healer of the Year

Drs. Allison Heinen and Elie Jarrouge: Hospitalist of the Year Award

Dr. Anita Kusnoor: D.A.V.E. Award for the dedicated academician who values excellence in patient care, teaching, and scholarly activity

Dr. Lee Lu: Joseph R. Guitreau Consummate Physician Award, the highest GIM award given in honor of a former colleague

DOM Awards Residency Program Graduation Awards

Ambulatory- Jaime Rueda, MD Ben Taub- Stephanie Sherman, MD MEDVAMC- Zaven Sargsyan, MD

BCM Awards John P. McGovern Outstanding Teacher Excellence Award (Medical School)

Lee Poythress, MD – Clinical Sciences Zaven Sargsyan, MD – Pre-clinical Sciences (2018), Clinical Sciences (2017)

Norton Rose Fulbright Award for Excellence in Teaching & Evaluation

Andrew Caruso, MD Diana Stewart, MD Erica Lescinskas, MD

Norton Rose Fulbright Award for Excellence in Educational Leadership

Erica Lescinskas, MD Early Career Faculty Award for Excellence in Patient Care

Dr. Stephanie Sherman

Graduating Class Outstanding Faculty Award

Dr. Andrew Caruso, assistant professor Dr. Zaven Sargsyan, assistant professor Dr. Stephanie Sherman, assistant professor Dr. Lee Poythress, associate professor

OTHER HONORS Dr. David Hyman, professor and chief of General Internal Medicine is listed in Castle Connolly’s list of Top Doctors in Houston.

Dr. Anna Kolpakchi: Lifetime Achievement Award

Dr. David Hilmers, professor, General Internal Medicine was named as a top Internal Medicine doctor by Houstonia Magazine in July 2017. Dr. Michelle Schmidt, assistant professor– Harris Health System was selected as one of the BCM Center of Excellence in Health Equity, Training and Research Junior Faculty Scholars for 2018-2019. Dr. Priti Dangayach, Assistant Professor, General Internal Medicine – Ben Taub Hospital, has received a Certificate of Recognition from the Harris Health System for distinguished service. The award recognizes for her excellence in leadership, mentoring and patient care. Dr. Lubna Khawaja, assistant professor, General Internal Medicine - Ben Taub, has received a Certificate of Recognition from the Harris Health System for distinguished service, in recognition of her excellence in leadership, mentoring and patient care.

Dr. Lee Poythress, associate professor, General Internal Medicine, Ben Taub Hospital, has been awarded the Distinguished Consultant Award from the Department of Emergency Medicine. This award is given to the consultant who the residents and faculty feel embody professionalism, communication, teaching and outstanding patient care.

Dr. Meroe Morse, assistant professor, General Internal Medicine, is an ongoing fellow ('19) and scholarship recipient in Integrative Medicine through Arizona Center of Integrative Medicine

Dr. Sabina Lee, associate professor, General Internal Medicine-VAMC, is a Texas ACP Wellbeing champion and will be involved with national ACP for the next 3 years for physician wellbeing.

Dr. Anita Kusnoor, associate professor, General Internal Medicine, received the Essential Skills in Medical Education (ESME) Faculty Scholarship last month from the Office of Faculty Development and the Academy of Distinguished Educators.

Dr. Sarah Candler, assistant professor, General Internal Medicine – MEDVAMC, received her certificate of completion of the Society of General Internal Medicine’s Leadership in Health

Policy program.

Dr. Ricardo Nuila, assistant professor, General Internal medicine has received a MacDowell Fellowship to continue his journalistic work on health disparities in Texas. The MacDowell Fellowship program is one of the most competitive artistic residencies in the country. Based in New Hampshire, it provides room and board for up to two months for visual artists, filmmakers, and journalists. Nuila will complete the residency in summer 2018.

Dr. Joslyn Fisher and Dr. Cara Foldes were nominated for exemplary Baylor Women of Excellence – women who exemplify excellence as well as Baylor’s other values (respect,

integrity, innovation and teamwork), in support of Women’s History Month.

http://www.macdowellcolony.org/

http://www.macdowellcolony.org/

Dr. Joslyn Fisher, associate professor, General internal Medicine participated in a panel discussion on Ethical Dilemmas in Health Policy with a focus on end of life care at the Texas Medical Center Headquarters in Houston.

Dr. Elizabeth Vaughan was honored by the BCM Office of Institutional Diversity, Inclusion and Equity for her efforts at the Community Health Worker Diabetes Education Program on June 30 at San Jose Clinic, where she helped educate the Health Equity Scholars in the BCM Center of Excellence in Health Equity.

Fellow, Hospital Medicine, Society of Hospital Medicine Andrew Caruso, MD Cory Ritter, MD

Fellow, American College of Physicians

Adelaide Adjovu, MD Anoop Agrawal, MD

IN THE MEDIA

Dr. Sarah Candler, assistant professor, General Internal Medicine – MEDVAMC, was interviewed for an April 23 article in MedPage Today titled “Do You Know Your Gen

Xers from Your Millennials?”

Dr. Ricardo Nuila, assistant professor, General Internal Medicine – Ben Taub - was interviewed for a June 6 TMC NEWS “On the Side” article, in which he talks about his penchant for great writing as well as practicing great medicine.

Dr. Niraj Mehta, associate professor, General Internal Medicine - Harris Health, was featured with a blog in kevinmd.com titled “A gentle reminder that healing begins with feeling.”

Dr. Winnie Hamilton, associate professor, General Internal Medicine, and director, Environmental Health Services, was part of a testing group that the New York Times created to study floodwaters around Houston. The resulting article, “Houston’s Floodwaters Are

Tainted, Testing Shows,” ran on Sept. 11; Dr. Hamilton was heavily cited in the article. Her work and that of several others who participated in the Times’ analysis showed that two

neighborhoods were contaminated with bacteria and toxins, possibly a result of several waste treatment plants, and that many other areas were also unsafe owing to bacteria and mold.

Dr. Ricardo Nuila and Dr. Michelle Schmidt were invited to speak on Pacifica Radio 90.1 KPFT – “So What’s Your Story?” on July 2018.

Dr. Joslyn Fisher co-authored “Intimate Partner Violence: A persistent post-disaster threat,”

BCM Blog, 10-18-17 https://blogs.bcm.edu/2017/10/18/intimate-partner-violence-a-persistent-post-disaster-threat/

https://www.medpagetoday.com/meetingcoverage/acp/72483

http://www.tmc.edu/news/2018/06/on-the-side-ricardo-nuila-m-d/

https://www.kevinmd.com/blog/2016/05/a-gentle-reminder-that-healing-begins-with-feeling.html

Dr. Rola El-Serag, assistant professor of Medicine, was interviewed by KPRC Channel 2 for an article about the VA’s fastest growing patient population; young female veterans. She also interviewed for a March 30 segment on the Houston Public Media radio show Houston Matters. The segment covered a new VA campaign to curb harassment against female veterans.

Professional Organization/ Offices Held

Sarah Candler, MD: Chair, Council of Resident / Fellow Members for the American College of Physicians Sarah Candler, MD: Member, Board of Regents for the American College of Physicians Sarah Candler, MD : Delegate, American Medical Association representing the American College of Physicians Sarah Candler, MD: Member, VA Task Force for the American College of Physicians Sarah Candler, MD: Member, VA Task Force for the Society of General Internal Medicine Sarah Candler, MD: Member, Master Clinician Task Force for the American College of Physicians Sarah Candler, MD: Member, Education Subcommittee of the Health Policy Committee for the Society of General Internal Medicine Sarah Candler, MD: Member, Health and Public Policy Committee, Texas Chapter of the American College of Physicians Sargsyan, Zaven, MD, Society to Improve Diagnosis in Medicine (SIDM), Member of the Education Committee on Diagnosis and Clinical Reasoning Lee Lu, MD: Co-Chair Resident clinic director interest group, SGIM

Lee Lu, MD: Fellow ACP

Lee Lu, MD: Clinical vignette committee, ACP and SGIM

Editorial Board:

Sarah Candler, MD: Editorial Advisory Board, Internal Medicine News Sarah Candler, MD: Co-Editor, “Fresh Look” Annals of Internal Medicine blog for early career and training physicians Stephanie Sherman, MD: Editor, “Global Morning Report.” Human Diagnosis Project (HDx.org)

Sargsyan, Zaven, MD: Contributing Editor, “Global Morning Report.” Human Diagnosis Project

McDowell, Scott, Pharm.D. Editorial reviewer Journal of the American Pharmacists Association McDowell, Scott, Pharm.D: Editorial reviewer Journal of Managed Care and Specialty Pharmacy.

McDowell, Scott, Pharm.D: Grant review committee The American Pharmacists Association Foundation

McDowell, Scott, Pharm.D: Research poster reviewer for Academy of Managed Care Pharmacy NEXUS

Geriatrics


October 2018

Baylor Geriatrics Section Annual Report

The Section of Geriatrics had a very challenging year. We survive and continue to deliver high quality, compassionate healthcare at many venues. At Houston Methodist Hospital (HMH), Geriatrics was ranked 29th in the nation out of 1,516 hospitals by U.S.News, and Baylor Geriatrics is the only Geriatrics at HMH. At Baylor St. Lukes Medical Center (BSLMC), Geriatrics was ranked as High Performing by U.S.News. Ownership changes at Park Plaza Hospital resulted in the displacement of our outpatient clinic. It was a very difficult move, but we have finally settled in affiliation with BSLMC to practice at Kirby Glen, a wonderful, accessible location less than 2 miles from the Medical Center. If the saying “Nothing worthwhile is easy” is true, then this arduous journey should lead us to the “promised land”. We hope to have fellows, faculty, and nurses caring for older people in a smoothly operating practice soon while enjoying free parking and easy access. We were also able to celebrated Dr. Robert J. Luchi’s 90th birthday. Dr. Luchi, who founded the Geriatrics section at BCM, and his wife, Jean, flew down from Kansas City for a wonderful opportunity, hosted by Rashmi Jaitly and the Huffington Center on Aging, to embrace successful aging and reflect on our incredible accomplishments.

Baylor Geriatrics is unique in providing care in numerous sites across institutional and geographic lines. Our private practice sees inpatients in consultation at BSLMC and HMH, provides continuing care in facilities close to the medical center and provides outpatient wound care. Our Harris Health practice at Ben Taub General and Quentin Mease Hospitals remain active and Harris Health provides the support for our House Calls program. The House Calls team was featured in a number of media outlets including Houston’s Channel 2. At the Michael E. DeBakey Veterans Affairs Medical Center patient care is provided across the continuum from the nursing home (CLC) to the clinic with a growing interest in providing Geriatric and Palliative Care in hospital and at home. We are honored to have the last of the “Greatest Generation” entrusted to our care at the VA. We have developed wound care as an area of expertise, now providing outpatient wound care at BSLMC, HMH, MEDVAMC, and to inpatients at HHS. Our Innovation interventions have decreased the exposure to drugs known to cause delirium for thousands of elders throughout the Methodist systems. Using EPIC to protect older patients from delirium was so novel that some of the team were invited to Wisconsin to the Epic User’s Group Meeting to present their work

Our faculty continues to play an important role training future clinicians and researchers in geriatrics and gerontology. Our educational impact outweighs our modest size. The Geriatrics track for our BCM medical students is on hiatus, but the student interest group (SAGI) under the leadership of BCM medical student Koby Kaplan has been revitalized. Dr. Major has updated ARTS (Age-Related ThemeS), our didactic course that occurs at the end of the second year of medical school. The Capstone course, the last didactics before graduation for BCM students, includes important input from Geriatrics faculty including Ursula Braun. Every BCM student did a house call with Geriatrics faculty members; this is a unique teaching experience, reminding learners that patients are real people. The house calls clinicians take the medical student with a University of Houston pharmacy student to create an interdisciplinary learning experience. We teach geriatrics to medicine core clerkship students monthly at Ben Taub Hospital. Many medical student choose electives with Geriatrics faculty. All BCM physician assistant students get training and mentorship at the MEDVAMC, coordinated in part by Mike Anderson, PA-C. To get a clinical perspective on their basic science work, Ph.D. candidates from the Huffington Center on

Aging rotate with us. All upper level BCM internal medicine residents spend four weeks on Geriatrics in a unique experience where they work for two weeks on the inpatient consult service at BSLMC and then spend two weeks out of the hospital exploring the continuum of care for older people. This innovation has been greatly appreciated and has lasting impact. We also train BCM family medicine residents and HMH family and internal medicine residents in a variety of venues. The Geriatrics PA residency is the only one of its type in the nation, recruiting excellent candidates from across the nation to do additional training in Geriatrics with our faculty. Its success with two slots spurred an increase to three slots for January 2019. Our Geriatric fellowship program is among the largest and most sought after in the nation lead by Angela Catic. Six first year fellows started in July and six graduated the day before. Annie Smith was our most famous graduating fellow, transported by a Houston Fire Department dump truck to the hospital to deliver Adrielle during the peak of Hurricane Harvey. Annie, husband Gregg, and Adrielle had the highest impact factor of any BCM member, appearing in hundreds of news outlets across the world including the Washington Post and People magazine. Another fellow finished her second year with a focus on quality improvement as it relates to house calls. This unique focus led Claire Campbell to be recognized as a national leader for education in this area. Another, Mariam Ahmed, started her second year focused on wound care. Under the leadership of Aimee Garcia, BCM Geriatrics created the only Geriatrics based academic wound care fellowship in the nation. New fellowship slots in palliative care in collaboration with M.D. Anderson Hospital have been organized through the efforts of Drs. Braun and Syed Imam. These will be filled outside the “match” this year, but are planned as an important “non-oncology” focused component of the best in the nation M.D. Anderson palliative care training program . Our educational efforts were not limited to trainees as BCM Geriatrics held its first CME course in June under the leadership of Syed Imam. It was well attended, very well received, and laid the foundation for further courses. The Elder Investor Fraud program, led by Bob Roush, has trained physicians, lawyers and financial advisers in more than half the states and is soon to be made electronic.

The true strength of our section is its people. Lurie McAdow, PA-C retired after more than twenty years of leading the PA efforts at the VA and Rose Dust, PA-C one of the early graduates of the PA residency in Geriatrics moved from the MEDVAMC to Colorado. Mike Anderson, PA-C, another graduate of the PA residency in Geriatrics, joined and will help direct the residency program. Marcia Yparraguirre, our long term administrator and steady hand upon our tiller, is now leading the AMS/HHS relationship at UT Houston. Khelli Simpson, joined BCM Geriatrics from billing to lead administration for the Section. Don Chen, a former fellow who helped develop Home based care at the VA, left as well. Vinh Nguyen, one of our former fellows, returned from California to join the Home Based Primary Care program at the VA. Francisco Loaiciga joined the MEDVAMC to provide palliative care in the homes of dying veterans. Kayla Hall, a nurse practitioner on the house calls team, left to join Methodist Orthopedics. And Nancy Wilson, who brought appreciation of social workers to multitudes of Geriatrics physicians, retired as well.

Our top-notch faculty received many accolades at the local and national levels. For example, we have more “super docs” than the other programs in Geriatrics in Houston. We represent BCM in major professional society meetings; our faculty holds leadership positions within the American Geriatrics Society, the Gerontological Society of America, American Association of House Call Medicine and American Medical Directors Association.

Geriatrics Section members contributed to research funding in 2018. While none of the funds gets directly credited to the Section, key collaborations with Psychiatry, Surgery, Otolaryngology, Endocrinology, Cardiovascular Research, Health Systems Research, and industry were critical to the

successes of our collaborators. With our colleagues in the Huffington Center on Aging, a large number of papers in scientific journals including the top journal in our field, Journal of the American Geriatrics Society. The enduring products include a wonderful book, Ethical Considerations and Challenges in Geriatrics, edited by Angela Catic that featured contributions of many of the BCM Geriatrics faculty, fellows and former fellows. The faculty has made a large number of local and regional presentations. The fellows and faculty had a major presence at the BCM Housestaff Research Day with all fellows presenting their efforts during that event. Similarly, the presence of the Geriatrics Section made up almost all the clinical poster presentation at the annual HCOA day.

In summary despite the wandering in the desert this year, BCM Geriatrics faculty was able to keep their focus on the next generation of providers, and our mission “to advance the quality of late life through exemplary research, education, patient care, and community outreach.”

Respectfully submitted, George E. Taffet, M.D., FACP Professor in Medicine Chief, Geriatrics Geriatrics and Cardiovascular Sciences Robert J. Luchi, M.D. Chair in Geriatric Medicine Baylor College of Medicine Head of the Division of Geriatrics Houston Methodist Hospital

AWARDS & HONORS Agarwal, Major, Taffet: Top Doctors in the City of Houston 2018

Garcia, Taffet: Top Geriatric Doctors Castle Connolly 2018

Catic, Selleck, Taffet: Super Doctors, Houston 2018

Agarwal: Woman of Excellence at Baylor College of Medicine. Co-Winner National Association of Hospital Pharmacy Prize 2017; Top Doctors in the City of Houston 2018

Braun: Program Leader, Palliative Care Fellowship Program, MEDVAMC; Leader, Breaking Bad News, CAPSTONE Course BCM

Catic: Program Director for Baylor Geriatrics Fellowship Program; Physician leader VA Physician Assistant Residency Program in Geriatrics; Leader, Educational Swaps Program, American Geriatrics Society; PA Collaborating Physician of 2018 MEDVAMC; Super Doctors, Houston 2018

Cintron: Clinical Supervisor Ethics Program, Harris Health;

Garcia: Director, MEDVAMC Wound Care Program; Top Geriatric Doctors Castle Connolly 2018

Jaitly: Director, HMH Wound Care Program

Johnson: Leader, Non-Physician Faculty Promotion Facilitator for BCM; Promotion to Assistant Professor, BCM

Khin: Director, Geriatric selectives for BCM medical students, Physician champion, Harris Health Wound Care Committee

Major: Leader, House Calls Program; Course Leader, Age-Related ThemeS, BCM; Top Doctors in the City of Houston 2018

Nguyen: Leader, Home Based Primary Care

Reyser: Director, Continuity Experience BCM Family Medicine residency program.

Roush: Leader, Elder Investor Fraud Program (with Naik and Kunik)

Salmeron: Leader, Post-Acute care program

Selleck: Super Doctors, Houston 2018;

Waterhouse: Promotion to Assistant Professor, BCM

Williams: Clinic Director, Baylor Geriatrics Senior Care Clinic; Member FGP Leadership, Dept. of Medicine, BCM

Papers

Agarwal

Multicomponent Interventions Reduce High-Risk Medications for Delirium in Hospitalized Older Adults. Adeola M, Azad R, Kassie GM, Shirkey B, Taffet G, Liebl M, Agarwal K. J Am Geriatr Soc. 2018 Aug;66(8):1638-1645. doi: 10.1111/jgs.15438. PMID: 30035315

Prevalence of Cognitive Impairment Among Elderly Patients Upon Hospital Admission Using Mini-Cog™ Assessments Performed by Advanced Pharmacy Practice Experience Students. Bui NA, Adeola M, Azad R, Swan JT, Agarwal KS, Sharma M, Liebl MG, Taffet GE. J Pharm Pract. 2018 Jan 1:897190018780591. doi: 10.1177/0897190018780591. PMID: 29909711

Unrecognized Cognitive Impairment and Its Effect on Heart Failure Readmissions of Elderly Adults. Agarwal KS, Kazim R, Xu J, Borson S, Taffet GE. J Am Geriatr Soc. 2016 Nov;64(11):2296-2301. doi: 10.1111/jgs.14471. PMID: 27676328.

Braun

Utilization of genomic testing in advanced non-small cell lung cancer among oncologists in the Veterans Health Administration. Arney J, Helm A, Crook T, Braun UK, Chen GJ, Hayes TG. Lung Cancer. 2018 Feb;116:25-29. doi: 10.1016/j.lungcan.2017.12.006. PMID: 29413047

Opioids in Cancer Pain: Right or Privilege? Jackson LK, Imam SN, Braun UK. J Oncol Pract. 2017 Sep;13(9):e809-e814. doi: 10.1200/JOP.2016.019216. PMID: 28557661

Catic

A Systematic Review of Practice Guidelines and Recommendations for Discontinuation of Cholinesterase Inhibitors in Dementia. Renn BN, Asghar-Ali AA, Thielke S, Catic A, Martini SR, Mitchell BG, Kunik ME. Am J Geriatr Psychiatry. 2018 Feb;26(2):134-147. doi: 10.1016/j.jagp.2017.09.027. Review. PMID: 29167065

Dementia and Hospital Readmission Rates: A Systematic Review. Pickens S, Naik AD, Catic A, Kunik ME. Dement Geriatr Cogn Dis Extra. 2017 Oct 19;7(3):346-353. doi: 10.1159/000481502. eCollection 2017 Sep-Dec. Review. PMID: 29282407

Cintron

Impact of rescheduling hydrocodone-combination products in an urban Texas county healthcare system. Shumway JW, Ran R, McClusky J, Rafique Z, Dark C, Peacock WF, Cintron A, Ludwig M. J Opioid Manag. 2018 Jul/Aug;14(4):257-264. doi: 10.5055/jom.2018.0457. PMID: 30234922

Imam

Opioids in Cancer Pain: Right or Privilege? Jackson LK, Imam SN, Braun UK. J Oncol Pract. 2017 Sep;13(9):e809-e814. doi: 10.1200/JOP.2016.019216. PMID: 28557661

Jackson

Opioids in Cancer Pain: Right or Privilege? Jackson LK, Imam SN, Braun UK. J Oncol Pract. 2017 Sep;13(9):e809-e814. doi: 10.1200/JOP.2016.019216.PMID: 28557661

Kazim


Taffet

Improved Cardiovascular Function in Old Mice After N-Acetyl Cysteine and Glycine Supplemented Diet: Inflammation and Mitochondrial Factors. Cieslik KA, Sekhar RV, Granillo A, Reddy A, Medrano G, Heredia CP, Entman ML, Hamilton DJ, Li S, Reineke E, Gupte AA, Zhang A, Taffet GE. J Gerontol A Biol Sci Med Sci. 2018 Aug 10;73(9):1167-1177. doi: 10.1093/gerona/gly034. PMID: 29538624

Multicomponent Interventions Reduce High-Risk Medications for Delirium in Hospitalized Older Adults. Adeola M, Azad R, Kassie GM, Shirkey B, Taffet G, Liebl M, Agarwal K. J Am Geriatr Soc. 2018 Aug;66(8):1638-1645. doi: 10.1111/jgs.15438. PMID: 30035315

Prevalence of Cognitive Impairment Among Elderly Patients Upon Hospital Admission Using Mini-Cog™ Assessments Performed by Advanced Pharmacy Practice Experience Students. Bui NA, Adeola M, Azad R, Swan JT, Agarwal KS, Sharma M, Liebl MG, Taffet GE. J Pharm Pract. 2018 Jan 1:897190018780591. doi: 10.1177/0897190018780591. PMID: 29909711


Transient activation of AMPK preceding left ventricular pressure overload reduces adverse remodeling and preserves left ventricular function. Nam DH, Kim E, Benham A, Park HK, Soibam B, Taffet GE, Kaelber JT, Suh JH, Taegtmeyer H, Entman ML, Reineke EL. FASEB J. 2018 Jul 19:fj201800602R. doi: 10.1096/fj.201800602R. PMID: 30024790

Short-Term Global Cardiovascular Disease Risk Prediction in Older Adults. Saeed A, Nambi V, Sun W, Virani SS, Taffet GE, Deswal A, Selvin E, Matsushita K, Wagenknecht LE, Hoogeveen R, Coresh J, de Lemos JA, Ballantyne CM. J Am Coll Cardiol. 2018 Jun 5;71(22):2527-2536. doi: 10.1016/j.jacc.2018.02.050. PMID: 29535064

Steroid receptor coactivator-2 (SRC-2) coordinates cardiomyocyte paracrine signaling to promote pressure overload-induced angiogenesis. Suh JH, Lai L, Nam D, Kim J, Jo J, Taffet GE, Kim E, Kaelber JT, Lee HK, Entman ML, Cooke JP, Reineke EL. J Biol Chem. 2017 Dec 29;292(52):21643-21652. doi: 10.1074/jbc.M117.804740. PMID: 29127200

Dissecting the role of myeloid and mesenchymal fibroblasts in age-dependent cardiac fibrosis. Trial J, Heredia CP, Taffet GE, Entman ML, Cieslik KA. Basic Res Cardiol. 2017 Jul;112(4):34. doi: 10.1007/s00395-017-0623-4. PMID: 28478479

Cardiac Resynchronization Therapy in Older Adults with Heart Failure. Lam PH, Taffet GE, Ahmed A, Singh S. Heart Fail Clin. 2017 Jul;13(3):581-587. doi: 10.1016/j.hfc.2017.02.011. Review. Erratum in: Heart Fail Clin. 2017 Oct;13(4):xi. PMID: 28602373

Murine Echocardiography of Left Atrium, Aorta, and Pulmonary Artery. Granillo A, Pena CA, Pham T, Pandit LM, Taffet GE. J Vis Exp. 2017 Feb 20;(120). doi: 10.3791/55214. PMID: 28287520

Williams

Tandem walking as a quick screening test for vestibular disorders. Cohen HS, Stitz J, Sangi-Haghpeykar H, Williams SP, Mulavara AP, Peters BT, Bloomberg JJ. Laryngoscope. 2018 Jul;128(7):1687-1691. doi: 10.1002/lary.27022. PMID: 29226324

Utility of quick oculomotor tests for screening the vestibular system in the subacute and chronic populations. Cohen HS, Stitz J, Sangi-Haghpeykar H, Williams SP, Mulavara AP, Peters BT, Bloomberg JJ. Acta Otolaryngol. 2018 Apr;138(4):382-386. doi: 10.1080/00016489.2017.1398838. PMID: 29141478

Vision Screening in Adults Across the Life Span. Cohen HS, Stitz J, Sangi-Haghpeykar H, Williams SP. South Med J. 2018 Feb;111(2):109-112. doi: 10.14423/SMJ.0000000000000762. PMID: 29394428

Health Services Research ANNUAL REPORT 2018

Contents

A. Faculty Listing B. Key Impacts C. Publications D. Presentations E. Methods and Products F. Awards and Honors G. Funding

Health Services Research Faculty

LAURA PETERSEN Professor (tenured) (Section Chief)

Primary

AMBER (AMY) AMSPOKER Assistant Professor (non-tenure track)

Primary

HODA BADR Associate Professor (tenured) Primary ISRAEL CHRISTIE Instructor Primary JESSICA DAVILA Associate Professor (tenured) Primary TRABER GIARDINA Assistant Professor (tenure track) Primary KYLER GODWIN Assistant Professor (tenure track) Primary VIVIAN HO Professor (tenured) Primary MOLLY HORSTMAN Assistant Professor (tenure track) Primary SYLVIA HYSONG Associate Professor (tenured) Primary

JENNIFER KRAMER Assistant Professor (non-tenure track)

Primary

LINDSEY MARTIN Assistant Professor (non-tenure track)

Primary

ASHLEY MEYER Assistant Professor (tenure track) Primary WHITNEY MILLS Assistant Professor (tenure track) Primary DANIEL MURPHY Assistant Professor (tenure track) Primary AANAND NAIK Associate Professor (tenured) Primary

NANCY PETERSEN Associate Professor (non-tenured)

Primary

PETER RICHARDSON Assistant Professor (non-tenure track)

Primary

KATHRYN ROYSE Instructor Primary

SHUBHADA SANSGIRY Assistant Professor (non-tenure track)

Primary

HARDEEP SINGH Professor (tenured) Primary RICHARD STREET JR Professor (non-tenured) Primary BARBARA TRAUTNER Associate Professor (tenured) Primary ANNETTE WALDER Instructor Primary

DONNA WHITE Assistant Professor (non-tenure track)

Primary

LECHAUNCY WOODARD Associate Professor (tenured) Primary MARK KUNIK Professor (tenured) Secondary JEFF CULLY Professor (tenured) Secondary

Key Impacts

Key Impact Label

Trautner BW, Grigoryan L, Petersen NJ, Hysong S, Cadena J, Patterson JE, Naik AD. Effectiveness of an Antimicrobial Stewardship Approach for Urinary Catheter-Associated Asymptomatic Bacteriuria. JAMA internal medicine. 2015 Jul 1; 175(7):1120-7.

PMID: 26010222 Overtreatment of asymptomatic bacteriuria (ASB) in patients with urinary catheters remains high. Health care professionals have difficulty differentiating cases of ASB from catheter-associated urinary tract infections. A multifaceted intervention targeting health care professionals who diagnose and treat patients with urinary catheters reduced overtreatment of ASB compared with standard quality improvement methods. These improvements persisted during a low-intensity maintenance period. The impact was more pronounced in long-term care, an emerging domain for antimicrobial stewardship.

Publication

Lindsay JA, Kauth MR, Hudson S, Martin LA, Ramsey DJ, Daily L, Rader J. Implementation of video telehealth to improve access to evidence-based psychotherapy for posttraumatic stress disorder. Telemedicine journal and e-health : the official journal of the American Telemedicine Association. 2015 Jun 1; 21(6):467-72.

PMID: 25714664 Increasing access to psychotherapy for PTSD is a primary focus of the VA healthcare system. Delivery of treatment via video telehealth can expand availability of treatment and be equally effective as in-person treatment. Development of specific strategies is needed to implement video telehealth services in complex healthcare systems, like the VA. This project conducted at 5 CBOCs was guided by the Promoting Action on Research Implementation in Health Services framework and used external facilitation to increase access to psychotherapy via video telehealth. Findings suggest that external facilitation is an effective and acceptable strategy to support providers as they establish clinics and make complex practice changes, such as implementing video telehealth to deliver psychotherapy

Publication

Singh H, Sittig DF. Advancing the science of measurement of diagnostic errors in healthcare: the Safer Dx framework. BMJ Qual Saf. 2015 Feb;24(2):103-10.

Diagnostic errors are major contributors to harmful patient outcomes, yet they remain a relatively understudied and unmeasured area of patient safety. Although they are estimated to affect about 12 million Americans each year in ambulatory care settings alone, both the conceptual and pragmatic scientific foundation for their measurement is under-developed. Health care organizations do not have the tools and strategies to measure diagnostic safety and most have not integrated diagnostic error into their existing patient safety programs. Further progress toward reducing diagnostic errors will hinge on our ability to overcome measurement-related challenges. In order to lay a robust groundwork for measurement and monitoring techniques to ensure diagnostic safety, we recently developed a multifaceted framework to advance the science of measuring diagnostic errors (The Safer Dx framework). We posit that the Safer Dx framework can be used by a variety of stakeholders including researchers, clinicians, health care organizations and policymakers, to stimulate both retrospective and more proactive measurement of diagnostic errors. The feedback and learning that would result will help develop subsequent interventions that lead to safer diagnosis, improved value of health care delivery and improved patient outcomes.

System Improvement

Singh H, Sittig DF. Measuring and improving patient safety through health information technology: The Health IT Safety Framework. BMJ Qual Saf. 2015. Sep 14. Epub ahead of print.

Health information technology (health IT) has potential to improve patient safety but its implementation and use have led to unintended consequences and new safety concerns. A key challenge to improving safety in health IT-enabled healthcare systems is to develop valid, feasible strategies to measure safety concerns at the intersection of health IT and patient safety. In response to the fundamental conceptual and methodological gaps related to both defining and measuring health IT-related patient safety, we propose a new framework, the Health IT Safety (HITS) measurement framework, to provide a conceptual foundation for health IT-related patient safety measurement, monitoring, and improvement. The framework proposes to integrate both retrospective and prospective measurement of HIT safety with an organization’s existing clinical risk management and safety programs. It aims to facilitate organizational learning, comprehensive 360 degree assessment of HIT safety that includes vendor involvement, refinement of measurement tools and strategies, and shared responsibility to identify problems and implement solutions. A long term framework goal is to enable rigorous measurement that helps achieve the safety benefits of health IT in real-world clinical settings.

System Improvement

Menon S, Murphy DR, Singh H, Meyer AN, Sittig DF. Workarounds and Test Results Follow-up in Electronic Health Record-Based Primary Care. Applied clinical informatics. 2016 Jun 22; 7(2):543-59.

Electronic health records (EHRs) have potential to facilitate reliable communication and follow-up of test results. However, limitations in EHR functionality remain, leading practitioners to use workarounds while managing test results. Workarounds can lead to patient safety concerns and signify indications as to how to build better EHR systems that meet provider needs.We conducted a secondary data analysis of quantitative and qualitative data from a national survey of PCPs practicing in the Department of Veterans Affairs (VA) and explored the use of workarounds in test results management. We used multivariate logistic regression analysis to examine the association between key sociotechnical factors that could affect test results follow-up (e.g., both technology-related and those unrelated to technology, such as organizational support for patient notification)

System Improvement

and workaround use. We conducted a qualitative content analysis of free text survey data to examine reasons for use of workarounds. Workarounds to manage EHR-based test results are common, and their use results from unmet provider information management needs. Future EHRs and the respective work systems around them need to evolve to meet these needs

Naik AD, Martin LA, Moye J, Karel MJ. Health Values and Treatment Goals of Older, Multimorbid Adults Facing Life-Threatening Illness. Journal of the American Geriatrics Society. 2016 Mar 1; 64(3):625-31.

This publication was cited in The John A. Hartford Foundation Change AGEnts Initiative white paper "Patient-Centered Medical Homes and the Care of Older Adults: How comprehensive care coordination, community connections, and person-directed care can make a difference". The paper provides a roadmap to guide primary care practices in how to enhance care for older, complex patients and their families.

System Improvement

VHA Directive 1088

Dr. Hardeep Singh co-chaired a work-group under The Office of Patient Care Services (10P4) to revise a previous directive (VHA Directive 2009-019) and to establish new national policy regarding communication of test results to providers and patients. Timely communication of test results is essential to ensuring safe and effective health care. Lack of timely follow-up of abnormal test results has been identified as a contributor to poor outcomes and can be a source of considerable anxiety to patients and families. The Directive cites 11 publications from center members and provides policies and guidance on how to improve timeliness of follow-up of test results and is consistent with VHA's goals of providing Veterans with quality health care. The Directive is now in place at all 150-plus VA facilities and impacting care for millions of veterans.

System Improvement

Explicit Quality Indicator Set for Measurement of Quality of Care in Patients with Cirrhosis

Dr. Fasiha Kanwal's work in cirrhosis quality measure development led to implementation of a performance measure as part of the Centers for Medicare and Medicare Service pay for performance program (HCC screening). This measure was also selected to be part of the GI measure set in AHIP, which is a national association representing nearly 1300 member companies providing health insurance coverage to more than 200 million Americans.

System Improvement

Murphy DR, Meyer AN, Bhise V, Russo E, Sittig DF, Wei L, Wu L, Singh H. Computerized Triggers of Big Data to Detect Delays in Follow-up of Chest Imaging Results. Chest. 2016 Sep 1; 150(3):613-20.

We applied a trigger in a repository hosting EHR data from all Department of Veterans Affairs health-care facilities and analyzed data from seven facilities. Using literature reviews and expert input, we refined previously developed trigger criteria designed to identify patients potentially experiencing delays in diagnostic evaluation of chest imaging flagged as "suspicious for malignancy." The trigger then excluded patients in whom further evaluation was unnecessary (ie, those with terminal illnesses or with already completed biopsies). The criteria were programmed into a computerized algorithm. Reviewers examined a random sample of trigger-positive (ie, patients with trigger-identified delay) and trigger-negative (ie, patients with an abnormal imaging result but no delay) records and confirmed the presence or absence of delay or need for additional tracking (eg, repeat imaging in 6 months). Analysis included calculating the trigger's diagnostic performance (ie, positive predictive value, negative predictive value, sensitivity, specificity). Application of triggers on "big" EHR data may aid in identifying patients experiencing delays in diagnostic evaluation of chest imaging results suspicious for malignancy.

Research Product

Publications

1. Arney J, Thurman K, Jones L, Kiefer L, Hundt NE, Naik AD, Woodard LD. Qualitative findings on building a partnered approach to implementation of a group-based diabetes intervention in VA primary care. BMJ Open. 2018 Jan 21;8(1):e018093. doi: 10.1136/bmjopen-2017-018093. PMID: 29358425 Impact Factor: 2.369

2. Arya M, Huang A, Kumar D, Hemmige V, Street RL Jr, Giordano TP. The Promise of Patient-Centered Text Messages for Encouraging HIV Testing in an Underserved Population. J Assoc Nurses AIDS Care. 2018 Jan - Feb;29(1):101-106.16/j.jana.2017.07.002. Epub 2017 Jul 11. PMID: 28739385 Impact Factor: 1.22

3. Arya M, Marek HG, Marren RE, Hemmige V, Street RL Jr, Giordano TP. Development and Evaluation of a Physician-Targeted Video to Promote HIV Screening. Health Promot Pract. 2018 Jun 1:1524839918783742. doi: 10.1177/1524839918783742. [Epub ahead of print]. PMID: 29938534 Impact Factor: 1.14

4. Badr H. Author's response to Porter and Keefe letter to the editor regarding 'new frontiers in couple-based interventions in cancer care: refining the prescription for spousal communication'. Acta Oncol. 2018 May;57(5):695-697. doi: 10.1080/0284186X.2017.1413249. Epub 2017 Dec 8. PMID: 29219013 Impact Factor 2.997

5. Badr H, Herbert K, Reckson B, Rainey H, Sallam A, Gupta V. Unmet needs and relationship challenges of head and neck cancer patients and their spouses. J Psychosoc Oncol. 2016 Jul-Aug;34(4):336-46. doi: 10.1080/07347332.2016.1195901. PMID: 27269579 Impact Factor: 3.455

6. Badr H, Lipnick D, Gupta V, Miles B. Survivorship Challenges and Information Needs after Radiotherapy for Oral Cancer. J Cancer Educ. 2017 Dec;32(4):799-807. doi: 10.1007/s13187-016-1048-8. PMID: 27193414 Impact Factor: 1.547

7. Baldwin JL, Singh H, Sittig DF, Giardina TD. Patient portals and health apps: Pitfalls, promises, and what one might learn from the other. Healthc (Amst). 2017 Sep;5(3):81-85. doi: 10.1016/j.hjdsi.2016.08.004. Epub 2016 Oct 3. PMID: 27720139 Impact Factor: none

8. Bamonti PM, Moye J, Naik AD. Pain is associated with continuing depression in cancer survivors. Psychol Health Med. 2018 Jun 14:1-14. doi: 10.1080/13548506.2018.1476723. [Epub ahead of print]. PMID: 29901408 Impact Factor 1.589

9. Barbieri AL, Fadzare O, Fan L, Singh H, Parkash V. Challenges in Communication from Referring Clinicians to Pathologists in the Electronic Health Record Era. J Pathol Inform. 2018 Apr 2;9:8. doi: 10.4103/jpi.jpi_70_17. eCollection 2018.. PMID: 29692945 Impact Factor none

10. Barrera TL, McIngvale E, Lindsay JA, Walder A. Obsessive-compulsive disorder in the Veterans Health Administration. Psychol Serv. 2018 May 24. doi: 10.1037/ser0000249. [Epub ahead of print]. PMID: 29792474 Impact Factor 1.544

11. Bergl PA, Nachal RS, Singh H. Diagnostic Error in the Critically III: Defining the Problem and 28853340 Exploring Next Steps to Advance Intensive Care Unit Safety. Ann Am Thorac Soc. 2018 Aug;15(8):903-907. doi: 10.1513/AnnalsATS.201801-068PS. PMID: 29742359 Impact Factor 2.790

12. Bhise V, Meyer AND, Menon S, Singhal G, Street RL Jr, Giardina T, Singh H. Patient perspectives on how physicians communicate diagnostic uncertainty: An experimental vignette study. Int J Qual Health Care. 2018 Feb 1;30(1):2-8. doi: 10.1093/intqhc/mzx170. PMID: 29329438 Impact Factor 2.342

13. Bhise V, Meyer AND, Singh H, Wei L, Russo E, Al-Mutairi A, Murphy DR. Errors in Diagnosis of Spinal Epidural Abscesses in the Era of Electronic Health Records. Am J Med. 2017 Aug;130(8):975-981. doi: 10.1016/j.amjmed.2017.03.009. Epub 2017 Mar 31. PMID: 28366427 Impact Factor 5.003

14. Bhise V, Rajan SS, Sittig DF, Morgan RO, Chaudhary P, Singh H. Defining and Measuring Diagnostic Uncertainty in Medicine: A Systematic Review. J Gen Intern Med. 2018 Jan;33(1):103-115. doi: 10.1007/s11606-017-4164-1. Epub 2017 Sep 21. PMID: 28936618 Impact Factor 3.449

https://www.ncbi.nlm.nih.gov/pubmed/?term=29358425
















15. Bhise V, Rajan SS, Sittig DF, Vaghani V, Morgan RO, Khanna A, Singh H. Electronic health record reviews to measure diagnostic uncertainty in primary care. J Eval Clin Pract. 2018 Jun;24(3):545-551. doi: 10.1111/jep.12912. Epub 2018 Apr 20. PMID: 29675888 Impact Factor 1.483

16. Bhise V, Sittig DF, Vaghani V, Wei L, Baldwin J, Singh H. An electronic trigger based on care escalation to identify preventable adverse events in hospitalised patients. BMJ Qual Saf. 2018 Mar;27(3):241-246. doi: 10.1136/bmjqs-2017-006975. Epub 2017 Sep 21. PMID: 28935832 Impact Factor 6.186

17. Biggerstaff KS, Frankfort BJ, Orengo-Nania S, Garcia J, Chiao EY, Kramer JR, White D. Validity of code based algorithms to identify primary open angle glaucoma (POAG) in Veterans Affairs (VA) administrative databases. Ophthalmic Epidemiol. 2018 Apr;25(2):162-168. doi: 10.1080/09286586.2017.1378688. Epub 2017 Sep 25. PMID: 28945495 Impact Factor 1.297

18. Bush RL, Jordan WD, Jr. Angioplasty and Stenting for Aortoiliac Disease: Technique and Results. 2018 March 1. Rutherford’s Vascular Surgery 9th Edition

19. Chopra V, Harrod M, Winter S, Foreman J, Quinn M, Krein S, Fowler KE, Singh H, Saint S. Focused Ethnography of Diagnosis in Academic Medical Centers. J Hosp Med. 2018 Apr 25. doi: 10.12788/jhm.2966. [Epub ahead of print]. PMID: 29694450 Impact Factor 2.203

20. Chou A, Trautner BW. Efficacy and Safety of short courses of antibiotic therapy for bacteremia caused by Enterobacteriaceae. Clin Infect Dis. 2018 Jul 18;67(3):482-483. doi: 10.1093/cid/ciy117. PMID: 29617741 Impact Factor 8.886

21. Cortes-Penfield NW, Trautner BW, Jump RLP. Urinary Tract Infection and Asymptomatic Bacteriuria in Older Adults. Infect Dis Clin North Am. 2017 Dec;31(4):673-688. doi: 10.1016/j.idc.2017.07.002. PMID: 29079155 Impact Factor 4.837

22. Davila JA, Cabral HJ, Maskay MH, Marcus R, Yuan Y, Chisolm N, Belton P, McKeithan L, Rajabuin S. Risk factors associated with multi-dimensional stigma among people living with HIV/AIDS who are homeless/unstably housed. AIDS Care. 2018 Oct;30(10):1335-1340. doi: 10.1080/09540121.2018.1484069. Epub 2018 Jun 7. PMID: 29879857 Impact Factor 1.22

23. Duron JF, Giardina TD. Teaching philosophies and practices in social work education: do the core competencies influence our consciousness? Social Work Education. 2018 Mar. DOI: 10.1080/02615479.2018.1450371 Impact Factor 0.89

24. Flash CA, Frost ELT, Giordano TP, Amico KR, Cully JA, Markham CM. HIV Pre-exposure Prophylaxis Program Implementation Using Intervention Mapping. Am J Prev Med. 2018 Apr;54(4):519-529. doi: 10.1016/j.amepre.2017.12.015. Epub 2018 Feb 9. PMID: 29433956. Impact Factor 4.527

25. Fraenkel L, Stolar M, Bates JR, Street RL Jr, Chowdhary H, Swift S, Peters E. Variability in Affect and Willingness to Take Medication. Med Decis Making. 2018 Jan;38(1):34-43. doi: 10.1177/0272989X17727002. Epub 2017 Aug 30. PMID: 28853340 Impact Factor 2.362

26. Franklin CL, Cuccurullo LA, Walton JL, Arseneau JR, Petersen NJ. Face to face but not in the same place: A pilot study of prolonged exposure therapy. J Trauma Dissociation. 2017 Jan-Feb;18(1):116-130. doi: 10.1080/15299732.2016.1205704. Epub 2016 Jun 27. PMID: 27348462 Impact Factor 1.682

27. Giardina TD, Baldwin J, Nystrom DT, Sittig DF, Singh H. Patient perceptions of receiving test results via online portals: a mixed-methods study. J Am Med Inform Assoc. 2018 Apr 1;25(4):440-446. doi: 10.1093/jamia/ocx140. PMID: 29240899 Impact Factor 3.689

28. Gregory ME, Bryan JL, Hysong SJ, Kusters I, Miltner R, Stewart D, Polacek N, Woodard L, Anderson J, Naik AD. Evaluation of a Distance Learning Curriculum for Interprofessional Quality Improvement Leaders. Am J Med Qual. 2018 Mar 1:1062860618765661. doi: 10.1177/1062860618765661. [Epub ahead of print]. PMID: 29577735 Impact Factor 1.662

29. Gregory ME, Russo E, Singh H. Electronic Health Record Alert-Related Workload as a Predictor of Burnout in Primary Care Providers. Appl Clin Inform. 2017 Jul 5;8(3):686-697. doi: 10.4338/ACI-2017-01-RA-0003. PMID: 28678892 Impact Factor 1.496














30. Grigoryan L, Zoorob R, Shah J, Wang H, Arya M, Trautner BW. Antibiotic Prescribing for Uncomplicated Acute Bronchitis Is Highest in Younger Adults. Antibiotics (Basel). 2017 Oct 27;6(4). pii: E22. doi: 10.3390/antibiotics6040022. PMID: 29077003 Impact Factor 2.033

31. Gupta K, Grigoryan L, Trautner BW. Urinary Tract Infection. Ann Intern Med. 2017 Oct 3;167(7):ITC49-ITC64. doi: 10.7326/AITC201710030. PMID: 28973215. Impact Factor: 17.202

32. Han A, Kunik ME. Feasibility of Training and Delivering Compassionate Touch in Long-Term Care. Clin Gerontol. 2017 Sep 19:1-9. doi: 10.1080/07317115.2017.1381212. [Epub ahead of print]. PMID: 29220625. Impact Factor 0.862

33. Hartmann CW, Palmer JA, Mills WL, Pimentel CB, Allen RA, Wewiorski NJ, Dillon KR, Snow AL. Adaptation of a nursing home culture change research instrument for frontline staff quality improvement use. Psychol Serv. 2017 Aug;14(3):337-346. doi: 10.1037/ser0000137. PMID: 288054 Impact Factor 1.544

34. Horstman MJ, Spiegelman A, Naik AD, Trautner BW. Urine Culture on Admission Impacts Antibiotic Use and Length of Stay: A Retrospective Cohort Study. Infect Control Hosp Epidemiol. 2018 May;39(5):547-554. doi: 10.1017/ice.2018.55. Epub 2018 Mar 27. PMID: 29582719 Impact Factor 3.55

35. Hortsman MJ, Spiegelman A, Naik AD, Trautner BW. National Patterns of Urine Testing During Inpatient Admission. Clin Infect Dis. 2017 Oct 1;65(7):1199-1205. doi: 10.1093/cid/cix424. PMID: 29370366 Impact Factor 8.886

36. Hortsman MJ, Spiegelman A, Naik AD, Trautner BW. Reply to Puig-Asensio et al. Clin Infect Dis. 2018 May 2;66(10):1647-1648. doi: 10.1093/cid/cix1100. PMID: 29272393 Impact Factor 8.886

37. Hundt NE, Helm A, Smith TL, Lamkin J. Cully JA, Stanley MA. Failure to Engage: A Qualitative Study of Veterans Who Decline Evidence-Based Psychotherapies for PTSD. Psychol Serv. 2017 Dec 21. doi: 10.1037/ser0000212. [Epub ahead of print]. PMID: 29265843. Impact Factor 1.544

38. Hysong SJ, Smitham K, SoRelle R, Amspoker A, Hughes AM, Haidet P. Mental models of audit and feedback in primary care settings. Implement Sci. 2018 May 30;13(1):73. doi: 10.1186/s13012-018-0764-3. PMID: 29848372 Impact Factor 4.345

39. Hysong SJ, SoRelle R, Broussard K, Petersen LA. Reports of unintended consequences of financial incentives to improve management of hypertension. PLoS One. 2017 Sep 21;12(9):e0184856. doi: 10.1371/journal.pone.0184856. eCollection 2017. PMID: 28934258 Impact Factor 2.806

40. Jacobs RC, Groth S, Farjah F, Wilson MA, Petersen LA, Massarweh NN. Potential Impact of "Take the Volume Pledge" on Access and Outcomes for Gastrointestinal Cancer Surgery. Ann Surg. 2018 Apr 24. doi: 10.1097/SLA.0000000000002796. [Epub ahead of print]. PMID: 29697444 Impact Factor 8.98

41. Jiang S, Street RL Jr. The effects of patient-centered communication, social capital, and internet use on patient empowerment: a cross-sectional study in China. Glob Health Promot. 2018 Mar. [Epub ahead of print]. PMID: 29521571 Impact Factor 0.522

42. Jiao L, Chen L, White DL, Tinker L, Chlebowski RT, Van Horn LV, Richardson P, Lane D, Sangi-Haghpeykar H, El-Serag HB. Low-fat Dietary Pattern and Pancreatic Cancer Risk in the Women's Health Initiative Dietary Modification Randomized Controlled Trial. J Natl Cancer Inst. 2018 Jan 1;110(1). doi: 10.1093/jnci/djx117. PMID: 28922784. Impact Factor 12.5589

43. Kanwal F, Tansel A, Kramer JR, Feng H, Asch SM, El-Serag HB. Trends in 30-Day and 1-Year Mortality Among Patients Hospitalized With Cirrhosis From 2004 to 2013. Am J Gastroenterol. 2017 Aug;112(8):1287-1297. doi: 10.1038/ajg.2017.175. Epub 2017 Jun 13. PMID: 28607480 Impact Factor 10.383

44. Kourkoumpetis T, Royse KE, Chen L, Ravishankar M, Ittman M, El-Serag HB, Jiao L. Differential Expression of Tight Junctions and Cell Polarity Genes in Human Colon Cancer. Exploratory Research and Hypothesis in Medicine. 2018 Apr 1. 3:14-19. Impact Factor none

45. Kramer JR, El-Serag H, Taylor TJ, White D, Asch S, Frayne S, Cao Y, Smith D, Kanwal F. Hepatitis C virus-related complications are increasing in women veterans: A national cohort study. J Viral Hepat. 2017 Nov;24(11):955-965. doi: 10.1111/jvh.12728. Epub 2017 Aug 16. PMID: 28815822 Impact Factor 4.122
















46. Kramer JR, Puenpatom A, Erickson K, Cao Y, Smith D, El-Serag H, Kanwal F. Real-world effectiveness of elbasvir/grazoprevir In HCV-infected patients in the US veterans affairs healthcare system. J Viral Hepat. 2018 May 31. doi: 10.1111/jvh.12937. [Epub ahead of print]. PMID: 29851265 Impact Factor 4.122

47. Krein SL, Greene MT, King B, Fowler KE, Trautner BW, Ratz D, Saint S, Roselle G, Clifton M, Kralovic SM, Martin T, Mody L. Assessing a National Collaborative Program To Prevent Catheter-Associated Urinary Tract Infection in a Veterans Health Administration Nursing Home Cohort. Infect Control Hosp Epidemiol. 2018 Jul;39(7):820-825. doi: 10.1017/ice.2018.99. Epub 2018 May 10. PMID: 29745358 Impact Factor 3.55

48. Kwan JL, Singh H. General Internists in Pursuit of Diagnostic Excellence in Primary Care: a #ProudtobeGIM Thread That Unites Us All. J Gen Intern Med. 2018 Apr;33(4):395-396. doi: 10.1007/s11606-018-4343-8. PMID: 29423627 Impact Factor 3.449

49. Lemoine N, Dajer A, Konwinski J, Cavanaugh D, Besthoff C, Singh H. Understanding diagnostic safety in emergency medicine: A case-by-case review of closed ED malpractice claims. J Healthc Risk Manag. 2018 Jul;38(1):48-53. doi: 10.1002/jhrm.21321. Epub 2018 May 12. PMID: 29752833 Impact Factor 1.05

50. Lin M, Kramer J, White D, Cao Y, Tavakoli-Tabasi S, Madu S, Smith D, Asch SM, El-Serag HB, Kanwal F. Barriers to hepatitis C treatment in the era of direct-acting anti-viral agents. Aliment Pharmacol Ther. 2017 Nov;46(10):992-1000. doi: 10.1111/apt.14328. Epub 2017 Sep 26. PMID: 28949020 Impact Factor 5.727

51. Lindsay JA, Hudson S, Martin L, Hogan J, Nessim M, Graves L, Gabriele J, White D. Implementing Video to Home to Increase Access to Evidence-Based Psychotherapy for Rural Veterans. Journal of Technology in Behavioral Science. 2017 Nov. https://doi.org/10.1007/s411347-017-0032-4. Impact Factor none

52. Lindsay JA, Keo-Meier C, Hudson S, Walder A, Martin LA, Kauth MR. Mental Health of Transgender Veterans of the Iraq and Afghanistan Conflicts Who Experienced Military Sexual Trauma. J Trauma Stress. 2016 Dec;29(6):563-567. doi: 10.1002/jts.22146. Epub 2016 Nov 21. PMID: 27868261 Impact Factor 2.721

53. Lomazzi C, Grassi V, Segreti S, Cova M, Bissacco D, Bush RL, Trimarchi S. Pre-operative Color Doppler Ultrasonography Predicts Endovenous Heat Induced Thrombosis after Endovenous Radiofrequency Ablation. Eur J Vasc Endovasc Surg. 2018 Jul;56(1):94-100. doi: 10.1016/j.ejvs.2018.02.025. Epub 2018 May 23. PMID: 29802054 Impact Factor 3.877

54. Lyratzopoulos G, Mendonca SC, Gildea C, McPhail S, Peake MD, Rubin G, Singh H, Hamilton W, Walter FM, Roland M, Abel GA. Associations between diagnostic activity and measures of patient experience in primary care: a cross-sectional ecological study of English general practices. Br J Gen Pract. 2018 Jan;68(666):e9-e17. doi: 10.3399/bjgp17X694097. Epub 2017 Dec 18. PMID: 29255108 Impact Factor 3.261

55. Ma L, Green SL, Trautner BW, Ramig RF, Maresso AW. Metals Enhance the Killing of Bacteria by Bacteriophage in Human Blood. Sci Rep. 2018 Feb 2;8(1):2326. doi: 10.1038/s41598-018-20698-2. PMID: 29396496 Impact Factor 4.259

56. Mapakshi S, Kramer JR, Richardson P, El-Serag HB, Kanwal F. Positive Predictive Value of International Classification of Diseases, 10th Revision, Codes for Cirrhosis and Its Related Complications. Clin Gastroenterol Hepatol. 2018 Feb 1. pii: S1542-3565(18)30113-7. doi: 10.1016/j.cgh.2018.01.042. [Epub ahead of print]. PMID: 29410051 Impact Factor 7.896

57. McBride CL, Akeroyd JM, Ramsey DJ, Nambi V, Nasir K, Michos ED, Bush RL, Jneid H, Morris PB, Bittner VA, Ballantyne CM, Petersen LA, Virani SS. Statin prescription rates and their facility-level variation in patients with peripheral artery disease and ischemic cerebrovascular disease: Insights from the Department of Veterans Affairs. Vasc Med. 2018 Jun;23(3):232-240. doi: 10.1177/1358863X18758914. Epub 2018 Mar 30. PMID: 29600737 Impact Factor 1.866

58. Meyer AND, Thompson PJ, Khanna A, Desai S, Mathews BK, Yousef E, Kusnoor AV, Singh H. Evaluating a mobile application for improving clinical laboratory test ordering and diagnosis. J Am









https://doi.org/10.1007/s411347-017-0032-4










Med Inform Assoc. 2018 Jul 1;25(7):841-847. doi: 10.1093/jamia/ocy026. PMID: 29688391 Impact Factor 3.698

59. Mignogna J, Martin LA, Harik J, Hundt N, Kauth M, Naik AD, Sorocco K, Benzer J, Cully J. "I had to somehow still be flexible": exploring adaptations during implementation of brief cognitive behavioral therapy in primary care. Implement Sci. 2018 Jun 5;13(1):76. doi: 10.1186/s13012-018-0768-z.. PMID: 29866141 Impact Factor 4.345

60. Miles SR, Harik JM, Hundt NE, Mignogna J, Pastorek NJ, Thompson KE, Freshour JS, Yu H, Cully JA. Delivery of mental health treatment to combat veterans with psychiatric diagnoses and TBI histories. PLoS One. 2017 Sep 8;12(9):e0184265. doi: 10.1371/journal.pone.0184265. eCollection 2017.. PMID: 28886114. Impact Factor 2.806

61. Miles SR, Khambaty, T, Petersen NJ, Naik AD, Cully JA. The Role of Affect and Coping in Diabetes Self-Management in Rural Adults with Uncontrolled Diabetes and Depressive Symptoms. J Clin Psychol Med Settings. 2018 Mar;25(1):55-65. doi: 10.1007/s10880-017-9527-6. PMID: 29332264 Impact Factor 0.9

62. Mills WL, Naik AD. Making and Executing Decisions for Safe and Independent Living (MEDSAIL): A Screening Tool for Community-Dwelling Older Adults. Self-Neglect in Older Adults: A Global, Evidence-Based Resource for Nurses and Other Healthcare Prov.Chapter 21. 2017 Jul. No Impact Factor

63. Mittal S, Kramer JR, Omino R, Chayanupatkul M, Richardson PA, El-Serag HB, Kanwal F. Role of Age and Race in the Risk of Hepatocellular Carcinoma in Veterans With Hepatitis B Virus Infection. Clin Gastroenterol Hepatol. 2018 Feb;16(2):252-259. doi: 10.1016/j.cgh.2017.08.042. Epub 2017 Sep 1. PMID: 28870660 Impact Factor 7.896

64. Mody L, Greene MT, Saint S, Meddings J, Trautner BW, Wald HL, Crnich C, Banaszak-Holl J, McNamara SE, King BJ, Hogikyan R, Edson BS, Krein SL. Comparing Catheter-Associated Urinary Tract Infection Prevention Programs Between Veterans Affairs Nursing Homes and Non-Veterans Affairs Nursing Homes. Infect Control Hosp Epidemiol. 2017 Mar;38(3):287-293. doi: 10.1017/ice.2016.279. Epub 2016 Dec 5. PMID: 27917728 Impact Factor 3.55

65. Molinari V, Hobday JV, Roker R, Kunik ME, Kane R, Kaas MJ, Mehrotra C, Williams CL, Robbins JC, Dobbs D. Impact of serious mental illness online training for certified nursing assistants in long term care. Gerontol Geriatr Educ. 2017 Oct-Dec;38(4):359-374. doi: 10.1080/02701960.2016.1188811. Epub 2016 Sep 22.. PMID: 28632071. Impact Factor none

66. Moye J, Jahn A, Norris-Bell R, Herman LI, Gosian J, Naik AD. Making meaning of cancer: A qualitative analysis of oral-digestive cancer survivors' reflections. J Health Psychol. 2018 Jan 1:1359105317753717. doi: 10.1177/1359105317753717. [Epub ahead of print]. PMID: 29355048 Impact Factor 2.182

67. Murphy DR, Meyer AND, Vaghani V, Russo E, Sittig DF, Wei L, Wu L, Singh H. Development and Validation of Trigger Algorithms to Identify Delays in Diagnostic Evaluation of Gastroenterological Cancer. Clin Gastroenterol Hepatol. 2018 Jan;16(1):90-98. doi: 10.1016/j.cgh.2017.08.007. Epub 2017 Aug 10. PMID: 28804030 Impact Factor 8.886

68. Murphy DR, Meyer AND, Vaghani V, Russo E, Sittig DF, Wei L, Wu L, Singh H. Electronic Triggers to Identify Delays in Follow-Up of Mammography: Harnessing the Power of Big Data in Health Care. J Am Coll Radiol. 2018 Feb;15(2):287-295. doi: 10.1016/j.jacr.2017.10.001. Epub 2017 Nov 1. PMID: 29102539 Impact Factor 3.383

69. Naik AD, El-Serag HB. Endoscopic ablation of low-grade dysplasia in Barrett's esophagus: Have all the boxes been checked for us to move on? Gastrointest Endosc. 2017 Jul;86(1):130-132. doi: 10.1016/j.gie.2017.01.032. PMID: 28610854 Impact Factor 7.204

70. Naik AD, Horstman MJ, Li LT, Paasche-Orlow MK, Campbell B, Mills WL, Herman LI, Anaya DA, Trautner BW, Berger DH. User-centered design of discharge warnings tool for colorectal surgery patients. J Am Med Inform Assoc. 2017 Sep 1;24(5):975-980. doi: 10.1093/jamia/ocx018. PMID: 28340218 Impact Factor 4.270

71. Nystrom DT, Baldwin J, Sittig DF, Singh H, Giardina TD. Methods for Patient-Centered Interface Design of Test Result Display in Online Portals. eGEMs. 2018 Jun. 6(1):15 Impact Factor none















72. Ohlemacher SI, Giblin DE, d’Avignon A, Stapleton AE, Trautner BW, Henderson JP. Enterobacteria secrete an inhibitor of Pseudomonas virulence during clinical bacteriuria. J Clin Invest. 2017 Nov 1;127(11):4018-4030. doi: 10.1172/JCI92464. Epub 2017 Sep 25. PMID: 28945201 Impact Factor 12.784

73. Olson APJ, Graber ML, Singh H. Tracking Progress in Improving Diagnosis: A Framework for Defining Undesirable Diagnostic Events. J Gen Intern Med. 2018 Jul;33(7):1187-1191. doi: 10.1007/s11606-018-4304-2. Epub 2018 Jan 29. PMID: 29380218 Impact Factor 3.449

74. Oxhandler HK, Giardina TD. Social Workers' Perceived Barriers to and Sources of Support for Integrating Clients' Religion and Spirituality in Practice. Soc Work. 2017 Oct 1;62(4):323-332. doi: 10.1093/sw/swx036. PMID: 28957580 Impact Factor none

75. Pickens S, Naik A, Catic A, Kunik ME. Dementia and Hospital Readmission Rates: A Systematic Review. Dement Geriatr Cogn Dis Extra. 2017 Oct 19;7(3):346-353. doi: 10.1159/000481502. eCollection 2017 Sep-Dec. PMID: 29282407 Impact Factor 2.886

76. Ratcliff C, Naik A, Martin LA, Moye JA. Examining cancer survivorship trajectories: Exploring the intersection between qualitative illness narratives and quantitative screening instruments. Palliat Support Care. 2017 Dec 28:1-7. doi: 10.1017/S1478951517000967. [Epub ahead of print]. PMID: 29282156 Impact Factor 1.199

77. Ratcliff CG, Barrera TL, Petersen NJ, Sansgiry S, Kauth MR, Kunik ME, Stanley MA, Cully JA. Recognition of anxiety, depression, and PTSD in patients with COPD and CHF: Who gets missed? Gen Hosp Psychiatry. 2017 Jul;47:61-67. doi: 10.1016/j.genhosppsych.2017.05.004. Epub 2017 May 12. PMID: 28807139 Impact Factor 2.989

78. Razjouyan J, Naik AD, Horstman MJ, Kunik ME, Amirmazaheri M, Zhao H, Sharafkhaneh A, Najafi B. Wearable Sensors and the Assessment of Frailty among Vulnerable Older Adults: An Observational Cohort Study. Sensors (Basel). 2018 Apr 26;18(5). pii: E1336. doi: 10.3390/s18051336. PMID: 29701640 Impact Factor 2.475

79. Redman JS, Natarajan Y, Hou JK, Wang J, Hanai M, Feng H, Kramer JR, Desiderio R, Xu H, El-Serag HB, Kanwal F. Accurate Identification of Fatty Liver Disease in Data Warehouse Utilizing Natural Language Processing. Dig Dis Sci. 2017 Oct;62(10):2713-2718. doi: 10.1007/s10620-017-4721-9. Epub 2017 Aug 31. PMID: 28861720 Impact Factor 2.613

80. Rehman H, Akeroyd JM, Ramsey D, Ahmed S, Merchant AT, Navaneethan SD, Petersen LA, Virani SS. Facility-level variation in diabetes and blood pressure control in patients with diabetes: Findings from the Veterans Affairs national database. Clin Cardiol. 2017 Nov;40(11):1055-1060. doi: 10.1002/clc.22769. Epub 2017 Aug 25. PMID: 28841246 Impact Factor 2.431

81. Renn BN, Asghar-Ali AA, Thielke S, Catic A, Martin SR, Mitchell BG, Kunik ME. A Systematic Review of Practice Guidelines and Recommendations for Discontinuation of Cholinesterase Inhibitors in Dementia. Am J Geriatr Psychiatry. 2018 Feb;26(2):134-147. doi: 10.1016/j.jagp.2017.09.027. Epub 2017 Oct 10.. PMID: 29167065 Impact Factor 2.868

82. Renn BN, Hundt NE, Sansgiry S, Petersen NJ, Kauth MR, Kunik ME, Cully JA. Integrated Brief Cognitive Behavioral Therapy Improves Illness Intrusiveness in Veterans With Chronic Obstructive Pulmonary Disease. Ann Behav Med. 2018 Jul 13;52(8):686-696. doi: 10.1093/abm/kax045. PMID: 29860524 Impact Factor 2.976

83. Richards KA, Ruiz VL, Murphy DR, Downs TM, Abel EJ, Jarrard DF, Singh H. Diagnostic evaluation of patients presenting with hematuria: An electronic health record-based study. Urol Oncol. 2018 Mar;36(3):88.e19-88.e25. doi: 10.1016/j.urolonc.2017.11.004. Epub 2017 Nov 21. PMID: 29169843 Impact Factor 2.41

84. Rinke ML, Singh H, Heo M, Adelman JS, O'Donnell HC, Choi SJ, Norton A, Stein REK, Brady TM, Lehmann CU, Kairys SW, Rice-Conboy E, Theissen K, Bundy DG. Diagnostic Errors in Primary Care Pediatrics: Project RedDE. Acad Pediatr. 2018 Mar;18(2):220-227. doi: 10.1016/j.acap.2017.08.005. Epub 2017 Aug 10. PMID: 28804050 Impact Factor 2.806

85. Royse KE, El-Serag HB, Chen L, White DL, Hale L, Sangi-Haghpeykar H, Jiao L. Sleep Duration and Risk of Liver Cancer in Postmenopausal Women: The Women's Health Initiative Study. J
















Womens Health (Larchmt). 2017 Dec;26(12):1270-1277. doi: 10.1089/jwh.2017.6412. Epub 2017 Sep 21. PMID: 28933583 Impact Factor 2.097

86. Scherr CL, Dean M, Clayton MF, Hesse BW, Silk K, Street RL Jr, Krieger J. A Research Agenda for Communication Scholars in the Precision Medicine Era. J Health Commun. 2017 Oct;22(10):839-848. doi: 10.1080/10810730.2017.1363324. Epub 2017 Sep 28. PMID: 28956728 Impact Factor 1.22

87. Scott AR, Sanderson CJ, Rush AJ, Alore EA, Naik AD, Berger DH, Suliburk JW. Constructing post-surgical discharge instructions through a Delphi consensus methodology. Patient Educ Couns. 2018 May;101(5):917-925. doi: 10.1016/j.pec.2017.12.004. Epub 2017 Dec 12. PMID: 29254751 Impact Factor 2.429

88. Shah R, Ho EY, Kramer JR, Richardson P, Sansgiry S, El-Serag HB, Hou JK. Hepatitis B Virus Screening and Reactivation in a National VA Cohort of Patients with Inflammatory Bowel Disease Treated with Tumor Necrosis Factor Antagonists. Dig Dis Sci. 2018 Jun;63(6):1551-1557. doi: 10.1007/s10620-018-5042-3. Epub 2018 Apr 16. PMID: 29663266 Impact Factor 2.613

89. Shah T, Patel-Teague S, Kroupa L, Meyer AND, Singh H. Impact of a national QI programme on reducing electronic health record notifications to clinicians. BMJ Qual Saf. 2018 Mar 5. pii: bmjqs-2017-007447. doi: 10.1136/bmjqs-2017-007447. [Epub ahead of print]. PMID: 29507122 Impact Factor 6.186

90. Shay LA, Baldwin AS, Betts AC, Marks EG, Higashi RT, Street RL Jr, Persaud D, Tiro JA. Parent-Provider Communication of HPV Vaccine Hesitancy. Pediatrics. 2018 Jun;141(6). pii: e20172312. doi: 10.1542/peds.2017-2312. Epub 2018 May 15. PMID: 29765009 Impact Factor 5.705

91. Singh H (co-chair), Ting DY. Closing the Loop. A Guide to Safer Ambulatory Referrals in the EHR Era. Institute for Healthcare Improvement. 2017 Nov. http://www.ihi.org/sites/search/pages/results.aspx?k=closing+the+loop.+a+guide+to+safer+ambulatory+referrals+in+the+ehr+era Impact Factor – does not applly

92. Singh H, Sittig DF. Frustrated with Your EHR? Don’t Blame Your Vendor — Safety Is a Shared Responsibility. NEJM Catalyst. 2017 Dec. https://catalyst.nejm.org/health-it-ehr-safety-shared-responsibility/ Impact Factor none

93. Sittig DF, Belmont E, Singh H. Improving the safety of health information technology requires shared responsibility: It is time we all step up. Healthc (Amst). 2018 Mar;6(1):7-12. doi: 10.1016/j.hjdsi.2017.06.004. Epub 2017 Jul 15. PMID: 28716376 Impact Factor none

94. Sittig DF, Salimi M, Aiyagari R, Banas C, Clay B, Gibson KA, Goel A, Hines R, Longhurst CA, Mishra V, Sirajuddin AM, Satterly T, Singh H. Adherence to recommended electronic health record safety practices across eight health care organizations. J Am Med Inform Assoc. 2018 Jul 1;25(7):913-918. doi: 10.1093/jamia/ocy033. PMID: 29701854 Impact Factor 3.698

95. Sittig DF, Singh H. SAFER electronic health records: safety assurance factors for EHR resilience. Library of Congress. 2017 Jul. ISBN 9781771881173. Impact Factor does not apply

96. Sittig DF, Singh H. Toward More Proactive Approaches to Safety in the Electronic Health Record Era. Jt Comm J Qual Patient Saf. 2017 Oct;43(10):540-547. doi: 10.1016/j.jcjq.2017.06.005. Epub 2017 Aug 30. PMID: 28942779 Impact Factor 1.13

97. Skelton F, Grigoryan L, Holmes SA, Poon IO, Trautner BW. Routine Urine Testing at the Spinal Cord Injury Annual Evaluation Leads to Unnecessary Antibiotic Use: A Pilot Study and Future Directions. Arch Phys Med Rehabil. 2018 Feb;99(2):219-225. doi: 10.1016/j.apmr.2017.10.005. Epub 2017 Oct 26. PMID: 29107038 Impact Factor 3.289

98. Skelton F, Suda K, Evans C, Trautner B. Effective antibiotic stewardship in spinal cord injury: Challenges and a way forward. J Spinal Cord Med. 2018 Jan 11:1-4. doi: 10.1080/10790268.2017.1396183. [Epub ahead of print] PMID: 29324181 Impact Factor 1.633

99. Smith MW, Brown C, Virani SS, Weir CR, Petersen LA, Akeroyd J, Garvin JH. Incorporating Guideline Adherence and Practice Implementation Issues into the Design of Decision Support for Beta-Blocker Titration for Heart Failure. Appl Clin Inform. 2018 Apr;9(2):478-489. doi: 10.1055/s-0038-1660849. Epub 2018 Jun 27. PMID: 29949816 Impact Factor 1.496

100. Smith MW, Hughes AM, Brown C, Russo E, Giardina TD, Mehta P, Singh H. Test results management and distributed cognition in electronic health record-enabled primary care. Health







http://www.ihi.org/sites/search/pages/results.aspx?k=closing+the+loop.+a+guide+to+safer+ambulatory+referrals+in+the+ehr+era

http://www.ihi.org/sites/search/pages/results.aspx?k=closing+the+loop.+a+guide+to+safer+ambulatory+referrals+in+the+ehr+era

https://catalyst.nejm.org/health-it-ehr-safety-shared-responsibility/

https://catalyst.nejm.org/health-it-ehr-safety-shared-responsibility/








Informatics J. 2018 Jun 1:1460458218779114. doi: 10.1177/1460458218779114. [Epub ahead of print]. PMID: 29905084 Impact Factor 1.833.

101. Spezia-Lindner NJ, Mitre V, Kunik ME. El Intercambio Cultural - A Hispanic Culture and Language Immersion Project in a Nursing Home. J Am Med Dir Assoc. 2018 Mar;19(3):272-273. doi: 10.1016/j.jamda.2017.12.096. Epub 2018 Feb 12. PMID: 29396190 Impact Factor 5.325

102. Stephenson E, DeLongis A, Bruel B, Badr H. Outpatient Pain Medication Use: An Electronic Daily Diary Study in Metastatic Breast Cancer. J Pain Symptom Manage. 2018 Apr;55(4):1131-1137. doi: 10.1016/j.jpainsymman.2017.11.032. Epub 2017 Dec 6. PMID: 29221847 Impact Factor 2.640

103. Street RL Jr, Liu L, Farber NJ, Chen Y, Calvitti A, Weibel N, Gabuzda MT, Bell K, Gray B, Rick S, Ashfag S, Agha Z. Keystrokes, Mouse Clicks, and Gazing at the Computer: How Physician Interaction with the EHR Affects Patient Participation. J Gen Intern Med. 2018 Apr;33(4):423-428. doi: 10.1007/s11606-017-4228-2. Epub 2017 Nov 29. PMID: 29188544 Impact Factor 3.449

104. Tayob N, Richardson P, White DL, Yu X, Davila JA, Kanwal F, Feng Z, El-Serag HB. Evaluating screening approaches for hepatocellular carcinoma in a cohort of HCV related cirrhosis patients from the Veteran's Affairs Health Care System. BMC Med Res Methodol. 2018 Jan 4;18(1):1. doi: 10.1186/s12874-017-0458-6. PMID: 29301497 Impact Factor 2.524

105. Thakur ER, Sansgiry S, Petersen NJ, Stanley M, Kunik ME, Naik AD, Cully JA. Cognitive and Perceptual Factors, Not Disease Severity, Are Linked with Anxiety in COPD: Results from a Cross-Sectional Study. Int J Behav Med. 2018 Feb;25(1):74-84. doi: 10.1007/s12529-017-9663-2. PMID: 28779469 Impact Factor 2.012

106. Thomas CL, Spitzmueller C, Amspoker AB, Modi V, Tran T, Naik AD, Woodard L, Auron A, Hysong SJ. A Systematic Literature Review of Instruments to Measure Coordination. J Healthc Manag. 2018 May-Jun;63(3):e1-e18. doi: 10.1097/JHM-D-16-00025. PMID: 29734285 Impact Factor 0.864

107. Trautner BW. Fluoroquinolones for urinary tract infection and within-household spread of resistant Enterobacteriaceae: the smoking gun. Clin Microbiol Infect. 2018 Apr 9. [Epub ahead of print]. PMID: 29649605 Impact Factor 5.394

108. Trautner BW. Lessons From a Year With Breast Cancer: An Academic Physician's Perspective. Ann Intern Med. 2018 Mar 20;168(6):448-449. doi: 10.7326/M17-1750. PMID: 29554681. Impact Factor: 17.202

109. Trautner BW. Walking the Dividing Line: The Challenges of Being a Doctor-Patient. J Clin Oncol. 2018 Apr 10;36(11):1173-1174. doi: 10.1200/JCO.2017.77.5494. Epub 2018 Feb 1. PMID: 29389231 Impact Factor 24.008

110. Trautner BW, Prasad P, Grigoryan L, Hysong SJ, Kramer JR, Rajan S, Petersen NJ, Rosen T, Drekonja DM, Graber C, Patel P, Lichtenberger P, Gauthier TP, Wiseman S, Jones M, Sales A, Krein S, Naik A. Protocol to disseminate a hospital-site controlled intervention using audit and feedback to implement guidelines concerning inappropriate treatment of asymptomatic bacteriuria. Implement Sci. 2018 Jan 19;13(1):16. doi: 10.1186/s13012-018-0709-x. PMID: 29351769 Impact Factor 4.345

111. Trieman K, McCormack L, Wagner L, Roach N, Moultrie R, Sanoff H, Bann C, Street RL Jr, Ashok M, Reeve BB. Factors affecting the communication experiences of newly diagnosed colorectal cancer patients. Patient Educ Couns. 2018 Sep;101(9):1585-1593. doi: 10.1016/j.pec.2018.04.016. Epub 2018 Apr 27.. PMID: 29803565 Impact Factor 2.429

112. Tulsky JA, Beach MC, Butow PN, Hickman SE, Mack JW, Morrison RS, Street RL Jr, Sudore RL, White DB, Pollak KJ. A Research Agenda for Communication Between Health Care Professionals and Patients Living With Serious Illness. JAMA Intern Med. 2017 Sep 1;177(9):1361-1366. doi: 10.1001/jamainternmed.2017.2005. PMID: 28672373 Impact Factor 16.538

113. Virani SS, Akeroyd JM, Ramsey DJ, Deswal A, Nasir K, Rajan SS, Ballantyne CM, Petersen LA. Health Care Resource Utilization for Outpatient Cardiovascular Disease and Diabetes Care Delivery Among Advanced Practice Providers and Physician Providers in Primary Care. Popul Health Manag. 2018 Jun;21(3):209-216. doi: 10.1089/pop.2017.0090. Epub 2017 Oct 10. PMID: 28994631 Impact Factor 1.296
















114. Virani SS, Kennedy KF, Akeroyd JM, Morris PB, Bittner VA, Masoudi FA, Stone NJ, Petersen LA, Ballantyne CM. Variation in Lipid-Lowering Therapy Use in Patients With Low-Density Lipoprotein Cholesterol ≥190 mg/dL: Insights From the National Cardiovascular Data Registry-Practice Innovation and Clinical Excellence Registry. Circ Cardiovasc Qual Outcomes. 2018 May;11(5):e004652. doi: 10.1161/CIRCOUTCOMES.118.004652. PMID: 29748356 Impact Factor 4.906

115. Weaver SJ, Che XX, Petersen LA, Hysong SJ. Unpacking Care Coordination Through a Multiteam System Lens: A Conceptual Framework and Systematic Review. Med Care. 2018 Mar;56(3):247-259. doi: 10.1097/MLR.0000000000000874. PMID: 29356720 Impact Factor 2.897

116. White DL, Hoogeveen RC, Chen L, Richardson P, Ravishankar M, Shah P, Tinker L, Rohan T, Whitsel EA, El-Serag HB, Jiao L. A prospective study of soluble receptor for advanced glycation end products and adipokines in association with pancreatic cancer in postmenopausal women. Cancer Med. 2018 May;7(5):2180-2191. doi: 10.1002/cam4.1426. Epub 2018 Mar 23. PMID: 29573228 Impact Factor 3.202

117. Whitehead NS, Williams L, Meleth S, Kennedy S, Epner P, Singh H, Wooldridge K, Dalal AK, Walz SE, Lorey T, Graber ML. Interventions to Improve Follow-Up of Laboratory Test Results Pending at Discharge: A Systematic Review. J Hosp Med. 2018 Feb 28. doi: 10.12788/jhm.2944. [Epub ahead of print]. PMID: 29489926 Impact Factor 2.203

118. Wittink MN, Walsh P, Yilmaz S, Mendu M, Street RL Jr, Chapman BP, Duberstein P. Patient priorities and the doorknob phenomenon in primary care: Can technology improve disclosure of patient stressors? Patient Educ Couns. 2018 Feb;101(2):214-220. doi: 10.1016/j.pec.2017.08.004. Epub 2017 Aug 8. PMID: 28844522 Impact Factor 2.429

119. Woodard LD, Adepoju OE, Amspoker AB, Virani SS, Ramsey DJ, Petersen LA, Jones LA, Kiefer L, Mehta P, Naik AD. Impact of Patient-Centered Medical Home Implementation on Diabetes Control in the Veterans Health Administration. J Gen Intern Med. 2018 Aug;33(8):1276-1282. doi: 10.1007/s11606-018-4386-x. Epub 2018 Apr 2. PMID: 29611089 Impact Factor 3.449

120. Zhou WY, El-Serag HB, Sada YH, Temple SL, Sansgiry S, Kanwal F, Davila JA. Determinants and Outcomes of Hospice Utilization Among Patients with Advance-Staged Hepatocellular Carcinoma in a Veteran Affairs Population. Dig Dis Sci. 2018 May;63(5):1173-1181. doi: 10.1007/s10620-018-4989-4. Epub 2018 Mar 5. PMID: 29508165 Impact Factor 2.613









Presentations

1. Godwin K, Gregory ME, Woodard LD. Tools for capabilities, coaching, conflict, and conditions. Baylor College of Medicine, Houston, TX. 2017 Jul 1.

2. Singh H. Improving Diagnosis in Health Care: An Implementation Workshop. Invited Expert Panelist. National Academic of Sciences, Engineering, and Medicine, Washington, DC. Invited Expert Panelist. 2017 Jul 17

3. Che XX, Brown C, Petersen LA, Hughes AM, Kuebeler M, Hysong SJ. A goal-driven approach to aggregating measures of PACT team performance. HSR&D/QUERI National Conference (2017). Arlington, VA. 2017 July 18.

4. Meyer AND, Murphy DR, Vaghani V, Russo E, Sittig DF, Wei L, Wu L, Singh H. Identifying Veterans with delays in diagnostic evaluation of cancer using electronic triggers. Oral Presentation. HSR&D/QUERI National Conference (2017). 2017 July 18.

5. Mills WL, Pimentel CB, Palmer JA, Snow AL, Hartmann CW. Formative evaluation of a new theory-driven framework to guide quality improvement in community living centers. HSR&D/QUERI National Conference (2017). Arlington, VA, 2017 July 18.

6. Murphy DR, Meyer AND, Vaghani V, Russo E, Sittig DF, Wei L, Wu L, Singh H. Electronic algorithms can efficiently detect delays in follow-up of abnormal mammograms. HSR&D/QUERI National Conference (2017). Arlington, VA. 2017 July 17.

7. Pimentel CB, Mills WL, Snow AL, Palmer JA, Hartman CM. Blended facilitation to support implementation efforts in VHA community living centers. Poster. HSR&D/QUERI National Conference (2017). Arlington, VA. 2017 July 18.

8. White DL, Kramer JR, Hysong SJ. Applied Design and Statistical Methods for Performing High Impact Meta-Analyses Workshop. HSR&D/QUERI National Conference (2017). Arlington, VA. 2017 July 18.

9. Barrera TL, Kunik ME, Stanley MA. Diagnostic Error among Veterans with Anxiety and Trauma-related Disorders. Poster. HSR&D/QUERI National Conference (2017). Arlington, VA. 2017 Jul 19.

10. O'Mahan P, Mehta PD, Rajan SS, Knox M, Yang C, Kuebeler M, Petersen LA. Method to develop facility-specific groups of VA hospital peers. HSR&D/QUERI National Conference (2017). Arlington, VA. 2017 July 19.

11. Petersen LA. The Power of Partnerships for High-Impact Research. Panel Discussion. HSR&D/QUERI National Conference (2017). Arlington, VA. 2017 Jul 19.

12. Brown CR, Kiefer L, Naik AD, Hundt NE, Jones L, Woodard LD. Promoting Veteran and Employee Engagement in Diabetes Management through the Transformational Elements of the PACT Model. Poster. HSR&D/QUERI National Conference (2017). Arlington, VA, 2017 July 18.

13. Hundt NE, Helm A, Smith TL, Lamkin J, Stevens JW, Cully JA, Stanley MA. Failure to Engage: A qualitative study of Veterans who decline evidence-based psychotherapies for PTSD. VA Health Services and Research Development Career Development Award Conference. Poster. Washington, DC. 2017 July 21.

14. Block P, Snow AL, Amspoker AB, Renn BN, Pickens S, Wilson N, Kunik M. Pain Interference in Persons with Dementia: A Beginning Exploration of Its Assessment. Poster. IAGG World Congress of Gerontology and Geriatrics. San Francisco, CA. 2017 July 23.

15. Pimentel CB, Mills WL, Hartmann CW, Snow AL. How to build a culture of quality improvement focused on the positive. Workshop. Pioneer Network Conference. Rosemont, IL. 2017 Aug 2.

16. Gregory M, Bryan JL, Hysong SJ, Kusters I, Polacek N, Woodard L, Naik AD, Godwin KM. Evaluation of an Interprofessional Quality Improvement Curriculum for Distributed Learners. Poster. National VA Quality Scholars Summer Institute Conference. Houston, TX. 2017 Aug 16.

17. Mapakshi S, Narayanan A, Conwell J, Bowen M, Miltner S, Eng J, Shirks A, Naik AD, Godwin KM. Building a VAQS Alumni Network: Needs and Preferences of VA Quality Scholars. Poster. National VA Quality Scholars Summer Institute Conference. Houston, TX. 2017 Aug 16.

18. Narayanan A, Bowen M, Conwell J, Miltner S, Eng J, Shirks A, Mapakshi S, Naik AD, Godwin KM. Analysis of Skills Used on the Job: Aligning the VAQS national Curriculum based on Alumni Feedback. Poster. National VA Quality Scholars Summer Institute Conference. Houston, TX. 2017 Aug 16.

19. Godwin KM, Woodard LD. Innovation and Systems Thinking: Friday Night in the ER. Speaker. 2017 VA Quality Scholars Summer Institute Conference. Houston, TX. 2017 Aug 19.

20. Giardina TD, Meyer AND. Diagnostic errors: Physician cognition and patient perspectives. Speaker. Neonatology Research Conference, Texas Children's Hospital. Houston, TX. 2017 Sep 14.

21. Meyer AND, Giardina TD. Physician cognition and patient perspectives. Speaker. Neonatology Research Conference, Texas Children's Hospital. Houston, TX. 2017 Sep 14.

22. Meyer AND, Murphy DR, Vaghani V, Russo E, Sittig DF, Wei L, Wu L, Singh H. Electronic algorithms can efficiently detect delays in follow-up of abnormal mammograms. Poster. Center for Innovations in Quality, Effectiveness and Safety (IQuESt) Steering Committee Meet and Greet Poster Session. Houston, TX. 2017 Sep 15.

23. Giardina TD, Meyer AND. Improving diagnosis: From the physician's mind to the patient's experience. Speaker. MEDVAMC Grand Rounds. Houston, TX. 2017 Sep 18.

24. Petersen LA. Financial incentives for improving health care quality. Invited Speaker. Advanced Health Economics, University of Texas School of Public Health. Houston, TX. 2017 Sep 20.

25. Godwin KM, Hortsman MJ, Walton N, Oliver B, Rosen T, Naik AD. QI Jumpstart: Development and Pilot Testing of a Brief, Intensive Quality Improvement Training Program for Clinicians. Invited Talk, Baylor College of Medicine 2017 Academy of Distinguished Educator’s, Annual Showcase of Educational Scholarship. Houston, TX. 2017 Sep 29.

26. Gregory ME, Bryan JL, Mendez A, Uriarte J, Woodard L. The Curriculum Development Process for an Interprofessional Training Program. Poster. Baylor College of Medicine Annual Showcase of Educational Scholarship. Houston, TX. 2017 Sep 29.

27. Stewart K, Martin L, Wendleton L, LaChappell K. Veteran Engagement Four Ways: Insights and Lessons Learned from Engaging Veterans at Four VA Research Centers. Virtual Presentation. Wisconsin Warrior Summit 2017. 2017 Sep 29.

28. Mapakshi S, Chang E, White DL, Kramer JR, Chiao EY. Impact of Protease Inhibitors on Incidence of HIV-Associated Kaposi Sarcoma: A Systematic Review. Poster. 2017 MEDVAMC Research Service Line Fall Fest. Houston, TX. 2017 Oct 1.

29. Ratcliff CG, Pao CW, Sansgiry S, Petersen NJ, Cully JA. Brief CBT for Medically Ill Primary Care Patients: How Much Does it Cost?. Invited Speaker. Collaborative Family Health Association. Houston, TX. 2017 Oct 1.

30. Cheraghi-Sohi S, Singh H, Litchfield I. Developing and Improving a Systems Approach to Diagnostic Safety in Primary Care. Invited Speaker. ISQua Conference 2017. London, UK. 2017 Oct 2.

31. Makeham M, Singh H, Sheikh A. Safety Standards for Digital Health Services – Learning from a Shared International Perspective. Invited Speaker. ISQua Conference 2017. London, UK. 2017 Oct 2.

32. Danforth KN, Davari SB, Slezak JM, Yi DK, Hahn EE, Luong TQ, Harrison TN, Mittman BS, Singh H, Brettler JW, Handler J, Kanter MH. Use of Targeted Lab Monitoring to Reduce Undiagnosed Hyponatremia and Preventable Hospitalizations. Oral. 10th International Diagnostic Error in Medicine Conference. Boston, MA. 2017 Oct 4.

33. Liberman AL, Rostanski SK, Ruff IM, Meyer AND, Maas MB, Prabhakaran S. Inter-rater agreement for the diagnosis of stroke versus stroke mimic after thrombolysis. Poster. 10th International Diagnostic Error in Medicine Conference. Boston, MA. 2017 Oct 4.

34. Meyer AND. Introduction to Diagnostic Error Short Course. 10th International Diagnostic Error in Medicine Conference. Boston, MA, 2017 Oct 4.

35. Meyer AND, Zwaan L. Society to Improve Diagnosis’s Fellows’ Research in Progress Feedback Session. Moderator. 10th International Diagnostic Error in Medicine Conference. Boston, MA. 2017 Oct 5.

36. Barrera T, Kunik M, Singh H, Stanley M. Diagnostic Discordance in Anxiety and Trauma-Related Psychiatric Disorders. 10th International Diagnostic Error in Medicine Conference. Boston, MA, 2017

Oct 5. 37. Cheraghi-Sohi S, Holland F, Reeves D, Singh H, Esmail A, Morris R, Small N, De Wet C, Campbell

S. Burden of Missed Diagnostic Opportunities in General Practice in the United Kingdom. Abstract. 10th International Diagnostic Error in Medicine Conference. Boston, MA. 2017 Oct 5.

38. Chopra V, Harrod M, Winter S, Foreman J, Quinn M, Krein S, Fowler K, Singh H, Saint S. Focused Ethnography to Improve Diagnosis in Teaching Hospitals: Introducing the Michigan Model of Diagnosis. Abstract. 10th International Diagnostic Error in Medicine Conference. Boston, MA. 2017 Oct 5.

39. Cifra CL, Dukes KC, Reisinger HS, Singh H, Herwaldt LA. Using Ethnography to Understand the Diagnostic Process in a Pediatric Intensive Care Unit. Abstract. 10th International Diagnostic Error in Medicine Conference. Boston, MA. 2017 Oct 5.

40. Danforth KN, Slezak JM, Chen LH, Hahn EE, Luong TQ, Harrison TN, Munoz-Plaza C, Anand SS,Y i DK, Mittman BS, Sim JJ, Singh H, Kanter MH. Risk Factors for Care-Gaps in Abnormal Lab Results Follow-up within a Large Integrated Health System. Abstract. 10th International Diagnostic Error in Medicine Conference. Boston, MA, 2017 Oct 5.

41. Hahn EE, Munoz-Plaza C, Harrison TN, Luong TQ, Anand SS, Yi DK, Slezak JM, Mittman BS, Sim JJ, Singh H, Kanter MH, Danforth KN. Factors Associated with Delayed Follow-up of Abnormal Labs: A Qualitative Exploration of Primary Care Physicians’ Perspectives. Abstract. 10th International Diagnostic Error in Medicine Conference. Boston, MA. 2017 Oct 5.

42. Hortsman MJ. Chronic Obstructive Pulmonary Disease. Speaker. 2017 Michael E. DeBakey VA Medical Center Primary Care Center of Excellence Curriculum. Houston, TX. 2017 Oct 5.

43. Kravet S, Bhatnagar M, Dwyer M, Singh H. Prioritizing Diagnostic Safety Efforts in the Physician Office Practice Setting. Oral. 10th International Diagnostic Error in Medicine Conference. Boston, MA. 2017 Oct 5.

44. Laws MB, Singh H, Taubin T, Wilson IB. Methods to Analyze Diagnostic Processes in Ambulatory Care. Abstract. 10th International Diagnostic Error in Medicine Conference. Boston, MA. 2017 Oct. 5.

45. Mahajan P, Alpern E, Baird-Cox K, Boothman R, Chamberlain J, Crosby K, Duffy E, Gegenheimer-Holmes A, Gerardi M, Giardina T, Mathias E, Mollen C, Radecki R, Ruddy R, Saleem J, Shaw K, Sittig DF, Vydiswaran V, Singh H. Opportunities to Improve Diagnosis in Acute Care – Findings from a Multi-Disciplinary Expert Panel. 10th International Diagnostic Error in Medicine Conference. Boston, MA. 2017 Oct 5.

46. Marshall K, Hohmuth B, Singh H. Delayed Diagnosis of Arterial Dissection and Stroke: A Learning Opportunity. Abstract. 10th International Diagnostic Error in Medicine Conference. Boston, MA. 2017 Oct 5.

47. Meyer AND, Khanna A, Thompson OJ, Desai S, Mathews BK, Yousef E, Kusnoor AV, Taylor JR, Singh H. An evaluation of the PTT Advisor mobile application for improving clinical laboratory test ordering and diagnosis. Poster. 10th International Diagnostic Error in Medicine Conference. Boston, MA. 2017 Oct. 5.

48. Meyer AND, Murphy DR, Vaghani V, Russo E, Sittig DF, Wei L, Wu L, Singh H. Electronic trigger-based measurement of delays in diagnostic evaluation of cancer: Time to think implementation. Poster. 10th International Diagnostic Error in Medicine Conference. Boston, MA. 2017 Oct 5.

49. Millenson ML, Baldwin J, Zipperer L, Singh H. Beyond Dr. Google: The Evidence about Consumer-Facing, Digital Tools for Diagnosis. Poster. 10th International Diagnostic Error in Medicine Conference. Boston, MA. 2017 Oct 5.

50. Rogith D, Iyengar S, Singh H. Application of Fault Tree Analysis for Insights into Diagnostic Error. Abstract. 10th International Diagnostic Error in Medicine Conference. Boston, MA. 2017 Oct 5.

51. Sheehan SE, Brunner M, Bruno M, Safdar N, Singh H. Detecting Patient Misidentification Errors in Diagnostic Radiology Exam Ordering. Oral. 10th International Diagnostic Error in Medicine Conference. Boston, MA. 2017 Oct 5.

52. Giardina TD, Baldwin J, Nystrom DT, Sittig DF, Singh H. Test Result Notification Via the Patient Portal: An Exploration Patients' Experiences. Poster. 10th International Diagnostic Error in Medicine Conference. Boston, MA. 2017 Oct 5.

53. Nystrom DT, Giardina TD, Baldwin J, Sittig DF, Singh H. Informing Action through Evidence: Examining Patient Perspective, Interpretation, and Use of Test Results from Patient Portals. Poster. 10th International Diagnostic Error in Medicine Conference. Boston, MA. 2017 Oct 5.

54. Meyer AND, Zwaan L. Teamwork and Diagnostic Error Research. Moderator. 10th International Diagnostic Error in Medicine Conference. Boston, MA. 2017 Oct 5.

55. Barrera TL, Kunik ME, Singh H, Stanley MA. Diagnostic Discordance in Anxiety and Trauma-Related Psychiatric Disorders. Oral. 2017 Diagnostic Error in Medicine 10th International Conference. Boston, MA. 2017 Oct. 5.

56. Giardina TD ,Greer-Smith R. Engaging Patients in Research: A Practical Workshop. Poster. 2017 Diagnostic Error in Medicine 10th International Conference. Boston, MA. 2017 Oct 5.

57. Singh H. Keynote Panel: Discussion of the Role of Diagnostic Error in Patient Safety. 10th International Diagnostic Error in Medicine Conference. Boston, MA. 2017 Oct 5.

58. Singh H. The Coalition in Action: Interventions, Advocacy and Driving Change. Invited Speaker. 2017 Diagnostic Error in Medicine 10th International Conference. Boston, MA, 2017 Oct 5.

59. Kanwal F, Kramer JR, Mapakshi S, Natarajan Y, Chayanupatkul M, Richardson PA, Li L, Desiderio R, Thrift AP, Asch SM, El-Serag HB. Risk of Hepatocellular Cancer in Patients with Non-alcoholic Fatty Liver Disease in Texas. Poster. 2017 Cancer Prevention and Research Institute of Texas Conference. Austin, TX. 2017 Oct 13.

60. Thakur ER, Jarbrink-Sehgal E, Martin L, Helm A, Kunik M, Lackner J, Dindo L, Smith T, Chan J, El-Serag HB. Behavioral Medicine Services for Patients with Irritable Bowel Syndrome: Development of a Referral Toolkit for Gastroenterology Providers. Poster. 2017 World Congress of Gastroenterology of the American College of Gastroenterology. Orlando, FL. 2017 Oct 15.

61. Kramer J, Purnpatom A, Erickson K, Cao Y, Smith DL, El-Serag HB, Kanwal F. Effectiveness of Elbasvir/Grazoprevir in patients with chronic hepatitis C and chronic kidney disease: Results from the Veterans Affairs system. Poster. American Association for the Study of Liver Diseases 68th Annual Meeting. Washington, DC. 2017 Oct 22.

62. LeMaire SA, Trautner BW, Rosengart TK. Building a Surgery Department Research Core Team to Support Surgical Investigators. Poster. 2017 American College of Surgeons Clinical Congress. San Diego, CA. 2017 Oct 22.

63. Chang E, Hartman C, Royse K, Kramer J, White D, Richardson P, Chiao EY. A Case Series of Nivolumab in Veterans with HIV Infection and Malignancy. Abstract. 2017 International Conference on Malignancies in HIV/AIDS. Bethesda, MD. 2017 Oct 23.

64. Chang E, Kramer J, Hartman C, Royse K, White D, Richardson P, Garcia J, Chiao EY. A case series of Nivolumab in Veterans with HIV infection and malignancy. Poster. 2017 - 16th International Conference on Malignancies in HIV/AIDS. Bethesda, MD. 2017 Oct 23.

65. Mapakshi S, Mbang P, Kramer JR, White DL, Chiao EY. Impact of Protease Inhibitor Based Regimens on Incidence of HIV associated Kaposi Sarcoma: A Systematic Review of Literature. Poster. 2017 International Conference on Malignancy in HIV/AIDS. Bethesda, MD, 2017 Oct 23.

66. Thrift AP, Royse KE, Richardson PA, Raychaudhury S, Desiderio R, White DL, Kramer JR, Chiao EY. Risk Of Non-AIDS-Defining Cancers Among Veterans With Well-Controlled HIV Infection. Abstract. 2017 International Conference on Malignancies in HIV/AIDS. Bethesda, MD, 2017 Oct 23.

67. Singh H. Diagnostic Errors: What VA Leaders Need to Know. Invited Speaker. VA Risk Management Bootcamp for Physician Leaders. Washington, DC. 2017 Oct 26.

68. Lo G, Cauley JA, Strayhorn MT, Jansen M, Hannon MJ, White DL, Green S, Kwoh CK. Feasibility of a novel approach to studying early knee osteoarthritis: An offspring study. Poster. 2017 - American College of Rheumatology. San Diego, CA. 2017 Nov 1.

69. Mehta PD, Rajan SS, Knox MK, Yang C, Kuebeler M, Petersen LA. Method to Develop Facility-Specific Groups of VA Hospital Peers. Poster. 2017 MEDVAMC Research Service Line Fall Fest. Houston, TX. 2017 Nov 1.

70. Meyer AND, Murphy DR, Vaghani V, Russo E, Sittig DF, Wei L, Wu L, Singh H. Electronic trigger-based measurement of delays in diagnostic evaluation of cance. Poster. 2017 MEDVAMC Research Service Line Fall Fest. Houston, TX. 2017 Nov 1.

71. Tayob N, Richardson P, Kanwal F, White DL, Yu X, Davila J, El-Serag HB. Phase 3 biomarker study for HCC surveillance using AFP, AFP-L3 and DCP: A prospective collection with retrospective blinded evaluation. Poster. 2017 - AASLD Annual Meeting. Washington, DC. 2017 Nov 1.

72. McCoy AB, Wright A, Singh H, Krousel-Wood M, Sittig DF. Electronic Health Record Safety: identifying Measures for Clinical Decision Support Quality. Poster. American Medical Informatics Association Annual Symposium. Washington, DC. 2017 Nov 4.

73. Cully JA, Stanley MA, Hundt N, Petersen N, Kunik M, Kauth M, Sansgiry S, Naik A, Sorocco K. Delivery of Brief CBT in Primary Care: A Pragmatic Clinical Trial. Poster. 2017 Association of Behavioral and Cognitive Therapies. San Diego, CA. 2017 Nov 16.

74. Godwin KM, Woodard LD, Gill A, Coleman N. Teamwork in Crisis Management. Speaker. Baylor College of Medicine, Houston, TX, 2017 Nov 16.

75. Whelen ML, Brandt CP, Deavers F, Hundt N, Stanley MA, Barrera TL, Cully JA. Integrating physical health into brief CBT for medically ill veterans with depression and anxiety. Poster. Association for Behavioral and Cognitive Therapies (2017). San Diego, CA. 2017 Nov 16.

76. Martin L. Focus Groups. Speaker. 2017 - VA Quality Scholars (VAQS) Skills and Methods Seminar presented virtually to nine sites across North America. Houston, TX. 2017 Nov 17.

77. Wendleton L, Martin LA, Stewart KR, LaChappell K. Veteran Engagement Three Ways: Insights and Lessons Learned from Engaging Veterans at Three VA Research Centers. VA Health Services Research & Development Cyberseminar. 2017 Nov 17.

78. Bush RL. Ablation Choices. Speaker. American Venous Forum Fall Fellows Course. Seattle, WA. 2017 Dec 1.

79. Bush RL. Micro-Phlebectomy. Speaker. American Venous Forum Fall Fellows Course. Seattle, WA, 2017 Dec 1.

80. Bush RL. Practical Thrombophilia Information. Speaker. American Venous Forum Fall Fellows Course. Seattle, WA, 2017 Dec 1.

81. Bush RL. Veins and the Pregnant Patient. Speaker. American Venous Forum Fall Fellows Course. Seattle, WA. 2017 Dec. 1.

82. Bush RL. Venous Ulcerations. Speaker. American Venous Forum Fall Fellows Course. Seattle, WA, 2017 Dec. 1.

83. Kirchner JE, Dollar KM, Smith TL, Ritchie MJ, Martin LA, Barrera TL, Lindsay JA. Using formal training to transfer evidence-based implementation strategy knowledge and skills. Oral. 2017 Science of Dissemination and Implementation in Health. Arlington, VA, 2017 Dec 4.

84. Mignogna J, Finley E, Sansgiry S, Cully JA, Post E, Wong G, Pierson D, MacCarthy, Kearney L, Wray L, MacCarthy J, Pomerantz A, Funderburk J, Benzer J. Effective psychotherapy in integrated care (EPIC): A realist evaluation approach to develop an organizational-focused intervention and implementation strategy. Poster. , Arlington, VA. 2017 Dec 4.

85. Singh H, Sahlmann B. Next Steps on Measurement and Improvement of Test Result Follow-up. Conference Call. VHA Primary Care Field Advisory Committee Conference Call. 2017 Dec 14.

86. Chou A, Sucgang R, Zechiedrich L, Trautner BW.. Discordant Ertapenem/Imipenem Susceptibilities in Enterobacter Causing Bloodstream Infections: Frequency and Outcomes. Abstract. 2018 1st Annual Texas Medical Center Antimicrobial Resistance and Stewardship Conference. Houston, TX. 2018 Jan 2.

87. Chou A, Sucgang R, Zechiedrich L, Trautner BW. Veterans are Special: Clinical Decision Tree not Sensitive for ESBL Status in Bacteremic Veterans. Abstract. 2018 - 1st Annual Texas Medical Center Antimicrobial Resistance and Stewardship Conference. Houston, TX. 2018 Jan 2.

88. Grigoryan L, Nash S, Trautner BW. Exploring Primary Care Provider Prescribing Decisions for Urinary Tract Infections. Poster. Texas Medical Center Antimicrobial Resistance and Stewardship Conference. Houston, TX. 2018 Jan 17.

89. Trautner BW. Asymptomatic Bacteriuria Collaborative Update. Speaker. 2018 1st Annual Texas Medical Center Antimicrobial Resistance and Stewardship Conference. Houston, TX. 2018 Jan 17.

90. Hou JK, Taylor R, Gonzalez I, El-Serag HB, Naik A, Arney J. Patient Experiences with Colorectal Cancer Surveillance (CRC) in Inflammatory Bowel Disease (IBD): A Qualitative Study. Poster. , Las

Vegas, NV. 2017 Jan 18. 91. Trautner BW. City of Houston Antimicrobial Stewardship Project for Asymptomatic Bacteriuria.

Speaker. 2018 - Antimicrobial Resistance Research and Stewardship Conference. Houston, TX. 2018 Jan 19.

92. Ratcliff CG, Massarweh NN, Sansgiry S, Dindo L,Y u H, Berger D, Cully JA. Impact of Mental Health Diagnoses and Treatment on Outcomes after Colorectal Cancer Surgery. Poster. 2018 American Surgical Congress. Jacksonville, FL, 2018 Jan 30.

93. Trautner BW. Making Research Feasible for Busy Surgeons Through Infrastructure Support: Pros, Cons, and Lessons Learned the Hard Way. Speaker. Jacksonville, FL. 2018 Jan 30.

94. Jacobs RC, Groth S, Farjah F, Wilson MA, Petersen LA, Massarweh NN. Impact of ‘Take the Volume Pledge’ on Access & Outcomes for Gastrointestinal Cancer Surgery. Plenary Session. 13th Annual Academic Surgical Congress, Jacksonville, FL. 2018 Jan 31.

95. Singh H. Advanced Analytics & Artificial Intelligence: What every Executive Needs to Know. Invited Panelist. Enaxis Leadership Forum. Rice University. Houston, TX. 2018 Feb 1.

96. Horstman MJ. Caregivers and Care Transitions: Supporting Families in an Aging America. Speaker. 2018 MD Anderson Section of General Internal Medicine Clinical and Research Conference. Houston, TX. 2018 Feb 8.

97. Razjouyan J, Naik A, Horstman M, Kunik M, Amirmazaheri M, Zhou H, Sharafkhaneh A, Najafi B. Wearable Sensors: A Solution to Identify Frailty Status in the Remote, Home-based Settings. Poster. Clinical Scientist Training Program 2018 Annual Retreat. Houston, TX. 2018 Feb 15.

98. Petersen LA. Quality of Care. Panel Discussion. TMC Policy Institute Health Policy Course, Houston, TX. 2018 Feb 20.

99. Chang E, Yoder AK, Royse KE, White DL, Richardson P, Hartmann C, Sabichi A, Yen AE, Chiao EY. Immune-related adverse events in HIV-infected veterans and matched controls with Nivolumab. Poster. 15th Annual Dan L. Duncan Comprehensive Cancer Center Symposium Immunotherapy. Houston, TX. 2018 Mar 1.

100. Sittig DF, Wright A, Ash J, Singh H. Too Many Ways to Make an Error. Poster. 2018 - IEEE Conference on Biomedical and Health Informatics (BHI), Las Vegas, NV, 2018 Mar 4.

101. Thrift AP, Royse KE, Richardson PA, Raychaudhury S, Desiderio R, White DL, Kramer JR, Chiao E. Risk of Non-AIDS-Defining Cancers among Veterans with well-controlled HIV Infection. Poster. 2018 Conference on Retroviruses and Opportunistic Infections, Boston, MA. 20-18 Mar 4.

102. Thrift AP, White DL, Nguyen HP, Royse KE, Kramer JR, Chiao EY. Trends in incidence of Kaposi Sarcoma among males in all 50 United States between 2000 and 2013. Abstract. 2018 Conference on Retroviruses and Opportunistic Infections, Boston, MA. 2018 Mar 4.

103. Ozkaynak M, Drake C, Reeder B, Ferrarone P, Trautner B, Wald H. Workflow informed decision support tools for nursing homes. Poster. 2018 Healthcare Information and Management SYSTEMS Society Annual Conference. Las Vegas, NV. 2018 Mar 5.

104. Thrift AP, White DL, Nguyen HP, Royse KE, Kramer JR, Chiao EY. Poster. Boston, MA. 2018 Mar 5.

105. Garcia JM, Kramer JR, Richardson PA, White D, Raychaudhury S, Chang E, Hartman C, Chiao EY. Effect of Diabetes, Metabolic factors and Medications on Risk of Lung Cancer among HIV-Infected Veterans. Abstract. 2018 Annual Endocrine Society. Chicago, IL. 2018 Mar 17.

106. Badr H. Intervening with caregivers to improve patient care and outcomes. Plenary Session. 2018 - M D Anderson 6th State of the Science Cancer Research Symposium: Translating Cancer Survivorship and Energy Balance Research into Public Health. Houston, TX. 2018 Mar 23.

107. Petersen LA, Woodard LD, Naik AD, Hertz B. Partnered Research to Co-Create Sustainable Interventions in the VA Health Care System. Workshop Presentation. Society of General Internal Medicine Annual Meeting. Denver, CO. 2018 Apr 12.

Methods and Products Method or Product Name Brief Description

2X2 Functional Health Literacy/Patient Activation Matrix (PI: LeChauncy Woodard)

The Functional Health Literacy/Activation Matrix tool was developed to provide personalized health information to clinicians to improve communication and coordination of self-management at the point of care. Functional Health Literacy (FHL) and Patient Activation levels are directly related to levels of motivation to participate in chronic disease self-management. By classifying veterans into high/low categories for both FHL and Patient Activation, the 2x2 Literacy/Activation Matrix provides a concrete description of a prototypical veteran in each quadrant and suggests corresponding actions and communication strategies for clinicians to uniquely target self-management plans with Veterans. By assessing Veterans' levels of Functional Health Literacy (FHL) and Patient Activation a priori, providers were able to tailor and personalize their approach to collaborative goal-setting. This personalization helped optimize chronic disease self-management for a costly population of Veterans with treated by uncontrolled Type II Diabetes Mellitus.

AWARE: Alerts, Watch and Response Engine (PI: Hardeep Singh)

Abnormal test results do not always receive timely follow-up, even when providers are notified through electronic health record (EHR)-based alerts. Follow-up to abnormal test results in the outpatient setting is an important safety issue. The Houston Patient Safety team developed and did preliminary usability testing on a prototype software system to detect abnormal test result alerts lacking documented follow-up, and to present context-specific reminders to provider called the Alert Watch And Response Engine (AWARE).

CAUTI: Catheter Associated Urinary Tract Infection Intervention (PI: Barbara Trautner)

With VA HSR&D funding, we have developed an intervention to encourage guideline compliant practices concerning antibiotic use for urinary tract infections. Specifically we used audit and feedback plus a "fast and frugal" algorithm to substitute incorrect biases towards excessive use of antibiotics for prescribing decisions that were compliant with guidelines.

CBOC Mental Health Grand Rounds Program (PI: Mark Kunik)

The CBOC Mental Health Grand Rounds program is a partnership between the South Central Mental Illness, Research and Clinical Center (SC MIRECC) and Veterans Health Administration (VHA), Employee Education System (EES). Nationally known speakers from the VA and academia are invited to talk about cutting edge topics & evidence-based practices that address the mental health care needs of rural Veterans. The monthly live meetings are made available to CBOCs and parent facilities in VISN 16 through the VA Knowledge Network. Select programs are archived for delayed viewing. The VA EES provides Continuing Education Credits for a number of healthcare disciplines.

CPRS View Alert Notification Checklist (PI: Hardeep Singh)

A Checklist to Improve CPRS 'View Alert' Notifications: Recommendations for VA Facility Leadership and Staff was developed by the Houston Patient Safety team and a group of subject matter experts to assist VHA facilities in addressing the complexities involved in managing View Alerts. The Checklist provides facility leaders and staff with actionable, practical recommendations in a checklist-based format to ensure that View Alert notifications remain valuable for patient care.

CTR Toolkit: Communication of Test Results Toolkit (PI: Hardeep Singh)

The Houston Patient Safety team and a VA Workgroup comprised of subject matter experts developed a toolkit that offers practical guidance for facilities and clinical care teams to meet the requirements of VHA Directive 1088 for timely communication of test results to patients. The objectives of the toolkit are to: 1) describe useful practices, example workflows, and processes necessary to implement a safe, effective, and efficient method of timely outpatient test result communication to providers and patients; and 2) provide recommendations for system-level monitoring of outpatient test result communication to patients, and define the parameters and methodology involved in achieving this. Topics addressed include test result follow-up responsibilities, test result categories, CPRS View Alerts, team-based approaches to facilitate test result follow-up, vulnerable areas including handoffs in care, current methods to notify patients and measurement and reporting of test result notification.

Customized Peer Facility Groups for VISNs (PI : Laura Petersen)

Dr. Laura Petersen's team created customized peer facility groups for VISNs. These peer facility groups allow Network managers to fairly compare their facilities (often of varying sizes, scopes of service, and missions) to facilities in other Networks. In the past 13 years, 11 VISNs have sought out our team to provide peer facility groups for quality and efficiency comparisons and to help with resource allocation. VISNs 11 and 12 have reported continuous use of the Houston-generated peer groups across their component facilities since 2004.

EHR Trigger Tool Methodology (PI: Hardeep Singh)

The EHR Trigger Tool Methodology was developed for mining EHR data to detect delays in diagnostic evaluation of cancer. The computerized algorithms and SQL code to mine this data are products of this methodology. This tool is related to the Houston CREATE Project.

Manualized Motivational Interviewing and Behavioral Health Guides for Chronic Disease Self-Management (PI: Jeff Cully)

A pair of manuals was developed to guide the structure and delivery of a motivational interviewing and behavioral health intervention to improve chronic disease self-management. The manual reviewed by patients guided the content of the group sessions and ensured that materials were easily understood, even for those veterans with limited health literacy. The clinician manual contained the whole of the veteran manual, with specific notations and instructions for leading veterans through the group sessions. Together the manuals provided assurance for successful delivery of and fidelity to the content.

NLP/ Structured Data Element Integration in EHRs (PI: Salim Virani)

Natural Language Processing (NLP) was applied to the problem of ensuring that patients receive evidence-based medication prescribing for cardiovascular disease. The CREATE 4 project developed a method to incorporate NLP with structured data elements from the electronic health record to provide decision support to clinicians at the point of care. The effectiveness of this method in improving care for lipid disease will be tested in new HSRD IIR that will start in FY 17.

SAFER Guides (PI: Hardeep Singh)

Dr. Singh's Houston Patient Safety Center team worked with researchers at the University of Texas Health Science Center at Houston's School of Biomedical Informatics as well as researchers at the Oregon Health and Science University, the research corporation Westat, and the Office of the National Coordinator for Health Information Technology (ONC), who sponsored the project, to develop self-assessment guides intended to help organizations proactively detect and reduce patient safety risks associated with electronic health records (EHRs). This group collaboratively developed and beta tested guides for nine different areas that contain recommended practices for optimizing the safety and use of EHRs. These guides are freely available nationally and are being increasingly used by both organizations and vendors.

VA Directive 1088 (PI: Hardeep Singh)

The Houston Patient Safety team worked with The Office of Patient Care Services (10P4) to revise the previous directive (VHA Directive 2009-019) to establish policy regarding communication of test results to providers and patients. VHA is committed to the timely communication of test results, which is essential to ensuring safe and effective health care. Timely communication of test results to patients is essential for high quality patient-centered care. Lack of timely follow-up of abnormal test results has been identified as a contributor to poor outcomes and can be a source of considerable anxiety to patients and families. Patient involvement in test result follow-up is fundamental to improve safety in this area and is consistent with personalized proactive patient-driven care. Patients have a right to access personal health information and expect to be notified of test results in a timely manner. Enhancing timeliness of follow-up of test results is consistent with VHA's goals of providing Veterans with quality health care.

IDENTIFY: Toolkit for Patient Identification (PI: Hardeep Singh)

A Toolkit for the use of health IT in patient identification designed to improve health IT safety. This toolkit is the result of a multi-stakeholder collaborative workgroup chaired by Dr. Hardeep Singh through the Partnership for Health IT Patient Safety. This is the second set of Safe Practice Recommendations for the use of health IT in patient identification designed to improve health IT safety. IDENTIFY stands for: 1) INCLUDE: electronic fields containing patient identification data should consistently use standard identifier conventions; 2) DETECT: use a confirmatin process to help match the patient and the documentstion; 3) EVALUATE: use standard attributes and attribute formats in all transactions to improve matching; 4): NORMALIZE: use a standard display of patient attributes across the various systems; 5): TAILOR: include distinguishing information enhancing identification on screens printouts, and those areas that require interventions; 6): INNOVATE: integrate new technologies to facilitate and enhance identification; 7): FOLLOW-UP: implement monitoring systems to readily detect identification errors; 8). YIELD: include high-specificity active alerts and notifications to facilitate proper identification.

Awards and Honors 1. Amspoker

a. Journal Editorial Board: Clinical Gerontologist b. Journal Editorial Board: Journal of Clinical Psychology in Medical Settings

2. Badr a. Co-Leader, Cancer Prevention and Population Sciences Program, Dan L. Duncan Cancer Center b. Co-Leader, Cancer Survivorship Disease Oriented Working Group, Dan L Duncan Cancer Center c. Core Member, Head and Neck Disease Oriented Working Group, Dan L Duncan Comprehensive

Cancer Center d. Member, Editorial Board, Journal of Psychosocial Oncology e. Member, Scientific Review Group, ZCA1 TCRB-Y (J3) S, Fundamental Mechanisms of Affective

and Decisional Processes in Cancer Control f. Member, Editorial Board, Journal of Psychosocial Oncology g. Member, Department of Medicine Appointment and Promotions Committee h. Member, Editorial Board, Journal of Psychosocial Oncology i. Consulting Editor, Journal of Family Psychology j. Member, Editorial Board, Annals of Behavioral Medicine k. Editor, Special Issue, Journal of Psychosocial Oncology, Innovations and Real World Applications

of Relationship Research in C l. Member, Scientific Review Group NINR ZNR1 REV-M(34) NINR P20 and P30 Centers Meeting

Cancer m. Member, NCI Subcommittee J – Career Development

3. Bush a. Associate Editor, Global Journal of Medicine and Public Health b. Assistant Editor, Journal of Vascular Surgery, Venous and Lymphatics c. Journal Editorial Board, Journal of Vascular Surgery, Cases d. Journal Editorial Board, Women, Identities, and Culture e. Journal Editorial Board, Annals of Vascular Surgery f. Journal Editorial Board, World Journal of Surgery g. Journal Editorial Board, Journal of Vascular Surgery h. Texas Medical Association, Council on Medical Education i. American College of Surgeons, ACS Foundation, Secretary j. American College of Surgeons, ACS Foundation Board of Directors k. American College of Surgeons, ACS Foundation/ CFR Committee l. American Venous Forum, Chair, Education Council m. Association of VA Surgeons, Membership Committee n. Society for Vascular Surgery, Document Oversight Committee o. Vascular and Endovascular Surgery Society, Board of Directors, Foundation for Vascular

Innovation p. Assistant Editor, Journal of Vascular Surgery: Venous and Lymphatic Disorders q. Vascular surgery oral examiner, American Board of Surgery r. VA HSR Review Panel, Learning Healthcare Initiative Randomized Program Evaluation s. Assistant Editor, Journal of Vascular Surgery: Venous and Lymphatic Disorders t. Board of Directors, American Venus Forum u. Co-organizer/facilitator, Early Career Venous Specialist Session for American Venous Forum

Annual Meeting, Poster session 4. Davila

a. Member, National VA VIREC Steering Committee b. Member, Dan L Duncan Cancer Center c. Member, Biostatistician Recruiting Committee, Dan L Duncan Cancer Center d. Member, National VA HSR&D Service Working Group on Data Access, Storage, and Analysis

e. Member, BCM Faculty Research and Fellowship Support Committee f. Member, BCM Faculty Appointments and Promotions Committee g. Director, Design and Analysis Program, Center for AIDS Research (CFAR) BCM h. Editorial Board, World Journal of Gastroenterology i. Editorial Board, World Journal of Clinical Oncology

5. Godwin a. BCM, Master Facilitator, Team Launch b. Module Leader, Team Launch, Launch Pad Module 3, Applying Teamwork Tools, Part 2:

Coaching, Conflict, Capabilities and Conditions c. BCM. Co-Module Leader, Team Launch, Launch Pad Module 4, Putting it all together! d. BCM, Department of Medicine, Vice Chair Group for Quality Improvement and Innovation,

Evaluation Specialist e. Co-Director –Advanced Fellows National Curriculum Workgroup, Office of Academic Affiliations,

United States Department of Veterans Affairs f. Co-leader, Team Projects, Healthcare Quality Track, Quality Enhancement Program, Baylor

College of Medicine g. Team Member, Quality Enhancement Program Committee, Baylor College of Medicine h. Co-Director, VA Quality Scholars Coordinating Center, Center for Innovations in Quality,

Effectiveness and Safety (IQuESt), Michael E. DeBakey VA Medical Center i. Co-Director, Health Professions Education Evaluation and Research Fellowship, Center for

Innovations in Quality, Effectiveness and Safety (IQuESt), Michael E. DeBakey VA Medical Center j. Associate Director, Education Core, Center for Innovations in Quality, Effectiveness and Safety

(IQuESt), Michael E. DeBakey VA Medical Center 6. Horstman

a. BCM, GME Faculty Workgroup in Continuous Quality Improvement b. Society of Hospital Medicine, Committee Member, Performance Measurement and Reporting

Committee 7. Hysong

a. Member, Baylor College of Medicine Liaison Committee on Medical Education b. Member, Fulbright & Jaworski Faculty Excellence Award Review Committee c. Subject Matter Expert. U.S. Department of Veterans Affairs Modernization, Functional Review

Panel d. Subject Matter Expert. VHA Physician Burnout Research Summit e. Associate Director, VA Quality Scholars Coordinating Center f. VA Scientific Merit Review Board (this is an undersecretary level appointment) g. Steering Committee Member. International Audit and Feedback Collaborative Meta-Laboratories h. Executive Advisory Board Member, Career Development Award Enhancement Initiative, Health

Services Research and Development i. Review Panel: Annual Meeting of the Society for Industrial/Organizational Psychology – Program

Committee j. National Scientific Review Panel: Department of Veterans Affairs Health Services Research and

Development Scientific Merit Review Board – member k. Subject Matter Expert, VA Pay-for-Performance Initiative l. Steering Committee Member, International Audit and Feedback Meta-Laboratories m. Norton Rose Fulbright Faculty Excellence Award –Educational Leadership

8. Martin a. HSR&D Veteran Engagement Workgroup (national workgroup), Department of Veterans Affairs

9. Meyer a. Co-Chair The Society to Improve Diagnosis in Medicine’s Research Committee

10. Mills a. Member – National Advisory Panel, Suicide Awareness in Veterans Exiting Community Living

Centers, Department of Veterans Affairs

b. Member – VA Decision Making Capacity Education Planning Group (national workgroup for VA Dementia Steering Committee) Department of Veterans Affairs

c. Member, Public Policy Committee, Development Committee, Pioneer Network d. Member – Assessing Stage of Dementia and Decision-Making Capacity Workgroup Department of

Veterans Affairs e. Member, Suicide Awareness in Veterans Exiting Community Living Centers National Advisory

Panel, Department of Veterans Affairs f. Lead, Community Living Center Research Interest Group, Department of Veterans Affairs g. Member, Caring for Veterans with Serious Mental Illness in CLCs, Department of Veterans Affairs h. Member, Public Policy Committee, Development Committee, Pioneer Network i. Member, Houston Alliance to Address Dementia Leadership Council, Sheltering Arms Senior

Services Division, Neighborhood Centers Inc. j. Member Leadership Council Evaluation Work Group, Direct Care Worker of the Year Award

Committee, Care for Elders 11. Murphy

a. Medical Director, General Internal Medicine at Baylor Clinic b. Member, BCM Faculty Group Practice (FGP) Patient Quality & Safety Committee c. Director, Baylor St. Luke’s Medical Group Board of Directors d. Member, BCM Department of Medicine Quality Improvement and Innovations Vice Chair Group e. Member, BCM Faculty Group Practice (FGP) Business Intelligence Committee f. Member, BCM Faculty Group Practice (FGP) Pharmaceutical & Therapeutics (P & T) Committee g. Baylor College of Medicine Quality Improvement and Patient Safety, abstract review

12. Naik a. Associate Editor & Editorial Board Member: Clinical Gerontology b. Standing member, Patient-Centered Outcomes Research Institute (PCORI) c. Member, Association of Specialty Professors (ASP) d. BCM, Longitudinal Ambulatory Care Education (LACE) Steering Committee e. BCM Faculty Committee on Medical Student Curriculum Standing Committee Member f. BCM Faculty Standing Committee on Research Member g. Texas Medical Center Health Policy Institute h. Vice Chair of Quality Improvement and Innovations, Alkek Department of Medicine, Baylor College

of Medicine i. Director, Coordinating Center for VA Quality Scholars Program

13. Petersen, Laura a. Associate Chief of Staff for Research, Michael E. DeBakey VA Medical Center b. Chair, Internal Advisory Committee, CPRIT Training Program, “Cancer Prevention Post-Graduate

Training Program in Integrative Epidemiology c. Member, McNair Campus Steering Committee BCM Clinical Research Work Group d. Member, Boston/Bedford CHOIR VA HSR&D Center of Innovations Steering Committee e. Member, MEDVAMC Dean’s Committee (renamed Joint Executive Management Council in 2017) f. Member, MEDVAMC Quality, Safety, and Value (QSV) Board g. Member, Clinical Executive Board, MEDVAMC h. Member, Texas Medical Center Strategic Planning Initiative Steering Committee\ i. Member, Texas Medical Center Council of Research Directors j. Co-Chair, Texas Medical Center Clinical Research Design Team k. Health Policy Scholar, Center for Medical Ethics and Health Policy, BCM l. Member, Texas Medical Center Women’s Leadership Council m. Chief, Health Services Research Section, Department of Medicine, Baylor College of Medicine n. VA HSR&D Quality Enhancement Research Initiative (QUERI) Strategic Advisory (formerly

Research and Methodology) Committee o. Member, Association of Specialty Professors (ASP) p. Member, Executive Council, MEDVAMC

q. Member, Texas Medical Center Health Policy Institute r. Leader, MEDVAMC Research Value Stream s. Member, BCM Strategic Planning Advisory Committee t. Member, Greater Houston Healthconnect (GHH) Research Committee u. Member, BCM Center of Excellence – Health Equity, Training, and Research Advisory Council v. Invited Technical Expert, Evidence-based Synthesis Program (ESP), “Pay for Performance and

Veteran Care: Effects, Implementations, and Unintended Consequences” w. Fellow, American College of Physicians x. Elected Member, American Clinical and Climatological Association (ACCA) y. Elected Member, Association of American Physicians (AAP) z. Member, Selection Committee, 2018 Research Rehabilitation & Development (RR&D) Paul B.

Magnuson Award aa. Member, BCM Department of Medicine Vice Chair for Research Committee bb. Member, Selection Committee, Junior Investigator of the Year Award, Society of General Internal

Medicine, 2008 Annual Meeting; 2017 Annual Meeting; 2018 Annual Meeting cc. Member, Los Angeles Center for the Study of Healthcare Innovation, Implementation, and Policy

(CSHIIP) VA HSR&D Center of Innovations Steering Committee dd. Member, Performance Measurement Committee of the American College of Physicians ee. VA Under Secretary’ Award for Outstanding Achievement in Health Services Research, 2018

14. Petersen, Nancy a. Chair, American Statistical Association, Committee on Membership Recruitment and Retention b. Member of abstract selection committee for American Heart Association c. Reviewer for HSRD/QUERI National Conference d. Member of abstract selection committee for American Heart Association

15. Sansgiry a. Editorial Board Member, Journal of Pharmaceutical Analytics and Insights b. Member, Research & Development Committee, Veterans Affairs Medical Center

16. Singh a. Member, VA Field Research Advisory Committee (FRAC) b. Appointed to the Harris County Medical Society (HCMS) Health Information Technology (HIT)

Committee c. Nominated Member, National Quality Forum Improving Diagnostic Accuracy Committee d. Co-Chair, National Quality Forum Committee for Identification and Prioritization of HIT Patient

Safety Measures e. Member, Editorial Board, International Journal for Quality in Health Care f. Associate Editor, Diagnosis g. Co-Chair, Closing the Referral Loop Expert Panel, National Patient Safety, Foundation – Institute

for Healthcare Improvement, Boston, MA h. Patient Safety Expert of the Year 2017 – Texas award, Corporate Vision Magazine i. HHS Appointed Member, Clinical Laboratory Improvement Advisory Committee (CLIAC) j. Lead Research Consultant, VHA EPRP Measurement of Communication of Test Results k. Initiative l. International Journal for Quality in Health Care, Editorial Committee Board m. Steering Committee Member, Center for Health Systems and Safety Research, Australian Institute

of Health Innovation, Macquarie University, NHMRC Partnership Project: Delivering Safe and Effective Test Result Communication, Management and Follow-Up

n. Editorial Advisory Board, The Joint Commission Journal on Quality and Patient Safety o. International Review Panel for India Alliance Fellowship, The Wellcome Trust/DBT India Alliance

17. Trautner a. Ben and Margaret Love Foundation Bobby Alford Award for Academic Clinical Professionalism,

BCM, Director of Clinical Research, Department of Surgery, BCM b. Data Monitoring Committee member for VA Cooperative Studies Program #2004 “Microbiota or

Placebo after Antimicrobial Therapy for Recurrent C. difficile at Home” c. Invited member of SHEA Public Policy and Government Affairs Committee d. Chair of Review Panel for 2017 Healthcare Innovations Seed Grants, Department of Medicine e. Member, Antimicrobial Stewardship Executive Committee, Houston Health Department f. Norton Rose Fulbright Faculty Excellence Award, Enduring Educational Materials g. Editorial Board Member, Journal of Surgical Research h. NIH NIDDK ZRG1 DKUS-R 90 study section (urology)

18. White a. American Public Health Association, Epidemiology Section, National Research Meeting (Abstract

reviewer) b. Texas Medical Center Digestive Diseases Center (DDC) at Baylor College of Medicine, Member

(elected), NIDDK P30 site c. Dan L. Duncan Cancer Center at Baylor College of Medicine, Member (elected), NCI P30 site d. Center Translational Research in Inflammatory Disease (CTRID) at the Michael E. DeBakey VA

Medical Center, Associate Member (elected) e. BMC Gastroenterology (Ad hoc reviewer) f. Grant Reviewer, Pilot Research Grants, Dept. of Surgery, Michael E. DeBakey VA

19. Woodard a. Elected BCM, Faculty Senate Secretary b. BCM, Academic Council Representative\ c. Deputy Editor, Journal of General Internal Medicine

Funding

Agency ID

Project Title HSR Investigator

Source Total Funds

Start Date

End Date Status or Project Type

CDA 13-264 Integration of Peer Support Across the PTSD Continuum of Care

N. E. Hundt PhD - Awardee, Houston

HSR&D $269,100 10/1/2015 9/30/2020 Career Award

CIN 13-413 Center for Innovations in Quality, Effectiveness and Safety (IQuESt)

L. A. Petersen MD MPH - Center Director, Houston

HSR&D $2,166,300

10/1/2013 *Note: Funding renewed for another 5 years beginning 10/1/2018

9/30/2018 HSR&D Core Funding

CRE 12-033 Automated Point-of-Care Surveillance of Outpatient Delays in Cancer Diagnosis

H. Singh MD MPH - PI, Houston G. J. Chen PhD MD MPH - Co-Investigator, Houston A. Meyer PhD - Co-Investigator, Houston D. Murphy MD - Co-Investigator, Houston M. W. Smith PhD - Co-Investigator, Houston N. J. Petersen PhD - Biostatistician, Houston

HSR&D $1,025,600

6/1/2013 9/30/2017 Data Collection

CRE 12-035 Identifying and Delivering Point-of-care Information to Improve Care Coordination

L. A. Petersen MD MPH - PI, Houston S. J. Hysong PhD MA BA - Co-PI, Houston A. Amspoker PhD - Biostatistician, Houston

HSR&D $864,672 4/1/2013 12/31/2017 Data Collection

CRE 12-310 Adapting and Implementing the Blended Collaborative Care Model in CBOCs

N. J. Petersen PhD - Co-Investigator, Houston


CRE 12-314 A Computer-Assisted Cognitive Behavioral Therapy Tool to Enhance Fidelity in CBO

M. Kauth PhD - Co-Investigator, Houston J. A. Lindsay PhD - Co-Investigator, Houston


CRE 12-426 Point-of-care health literacy and activation information to improve diabetes care

L. D. Woodard MD MPH - PI, Houston N. E. Hundt PhD - Co-Investigator, Houston A. D. Naik MD BA - Co-Investigator, Houston R. Street PhD MA - Co-Investigator, Houston A. Amspoker PhD - Biostatistician, Houston


IIR 12-383 Linking Clinician Interaction and Coordination to Clinical Performance in VA PACT

S. J. Hysong PhD MA BA - PI, Houston A. D. Naik MD BA - Co-Investigator, Houston L. D. Woodard MD MPH - Co-Investigator, Houston A. Amspoker PhD - Biostatistician, Houston


IIR 12-395 Identifying and Reducing Catheter-Related Complications

B. Trautner MD - Co-Investigator, Houston


IIR 13-315 Effectiveness and Implementation of Brief Cognitive Behavioral Therapy in CBOCs

J. Cully PhD MEd - PI, Houston T. L. Barrera PhD - Co-Investigator, Houston N. E. Hundt PhD - Co-Investigator, Houston M. Kauth PhD - Co-Investigator, Houston M. E. Kunik MD MPH - Co-Investigator, Houston L. Martin PhD - Co-Investigator, Houston M. A. Stanley PhD - Co-Investigator, Houston N. J. Petersen PhD - Biostatistician, Houston


IIR 14-101 A multi-level intervention to improve cancer care for hepatocellular carcinoma

J. Davila PhD MS BS - PI, Houston T. P. Giordano MD MPH - Co-Investigator, Houston F. Kanwal MBBS MD - Co-Investigator, Houston L. Martin PhD - Co-Investigator, Houston A. D. Naik MD BA - Co-Investigator, Houston S. Sansgiry PhD - Co-Investigator, Houston P. A. Richardson PhD MS BA - Biostatistician, Houston


IIR 15-085 Alignment of Treatment Preferences and Repair Type for Veterans with AAA

P. Kougias MD MSc - Co-Investigator, Houston


IIR 16-072 Determining and targeting reasons for low statin use to improve guideline-concordant statin therapy in high-risk patients

S. Virani MD - PI, Houston

HSR&D $38,309 7/1/2017 6/30/2021 Start Up Activities

NRI 12-415 Telephone Assessment and Skill-Building Intervention for Informal Caregivers

J. A. Anderson PhD NP - Co-Investigator, Houston K. Godwin PhD MPH BS - Consultant, Houston


PPO 16-106 Brief Psychotherapy for Depression in Primary Care: Identifying Successful Clinical Practices

J. Cully PhD MEd - Co-Investigator, Houston S. Sansgiry PhD - Co-Investigator, Houston

HSR&D $4,516 7/1/2017 6/30/2018 Start Up Activities

TPP 97-004 Training Program for Fellows (post Ph.D.s) at Houston COIN

L. A. Petersen MD MPH - Director, Houston

HSR&D $47,558 10/1/1996 9/30/2017 Supplemental Funding

TPR 06-101 Post Resident Training Program

L. A. Petersen MD MPH - Director, Houston

HSR&D $28,382 3/1/2006 9/30/2017 Supplemental Funding

USA 14-274 Presidential Early Career Award for Scientists and Engineers

H. Singh MD MPH - Awardee, Houston

HSR&D $75,000 1/1/2014 12/31/2018 Career Award

XXX XX-XXX

ADMINISTRATIVE AND TRAVEL REIMBURSEMENTS - Field Based Science Advisors (FBSAs)

L. A. Petersen MD MPH - Center Director, Houston A. MC - Co-Investigator, Reno

HSR&D $24,432 1/1/2000 9/30/2020 Administrative Funding

RSG 15-058 Psychosocial Intervention for Advanced Lung Cancer Patients and Caregivers

H. Badr, PhD - Principal Investigator, Houston

ACS $792,000 7/1/2105 6/30/2019 Data Collection

CA 187143 A Psychosocial Intervention for the Caregivers of Advanced Lung Cancer Patients


NIH R01 $2,473,983


XXX XX-XXX

Using Implementation Science to Guide Survivorship Care Planning Efforts


DDCC $50,000 6/1/2018 5/30/2019 Data Collection

QIS 18-201 Leading Healthcare Improvement: Leadership Training for Applying Improvement Strategies, start-up funding

K. Godwin, PhD - Principal Investigator, Houston

QUERI $56,275 6/1/2018 9/30/2018 Data Collection

17MCPRP33390011

Optimizing Patient-Initiated Post-Discharge Care for Patients with Heart Failure

M. Horstman, MD - Principal Investigator, Houston

AHA $70,000 1/1/2017 12/31/2018 Data Collection

XXX XX-XXX

Patient Priorities Care Pilot Study

A. Naik, MD - Principal Investigator, Houston

VA GEC $100,000 10/1/2017 9/30/2018 Data Collection

XXX XX-XXX

Integrating Patient Priorities Care and Social Work Case Management


VA ORH OSW

$230,000 10/1/2017 9/30/2018 Data Collection

XXX XX-XXX

Coordinating Center for the VA Quality Scholars Program


VA OAA $345,000 7/1/2014 9/30/2019 Fellowship

HX 16-075 Patient Centered Approach to Advanced Liver Disease

F. Kanwal, MD - Co-Principal Investigator, Houston; A. Naik, MD - Co-Principal Investigator, Houston


CRE 12-426 Point-of-care health literacy and activation information to improve diabetes care


VA CREATE

$273,700 3/1/2014 2/28/2018 Data Collection

XXX XX-XXX

Primary Specialty Care Redesign (Carealign) Implementation


Hartford Foundation

$108,806 1/1/2015 10/1/2018 Data Collection

IK2RX001241

Improving Veteran Transitions from VA Community living Centers to the Community


VA CDA 7/1/2014 6/30/2019 Data Collection

XXX XX-XXX

VA Advanced Fellowships in HSR


VA OAA $339,000 10/1/2013 9/30/2018 Data Collection

XXX XX-XXX

Houston BD-STEP program


VA OAA/NCI

$180,000 10/1/2015 9/30/2017 Fellowship

HX 17-066 Comparative Effectiveness of Alternative Strategies for Monitoring Hospital Surgical Performance

N. Massarweh MD – Principal Investigator; L. Petersen, MD, MPH - Co-Investigator; P. Richardson, PhD - Co-Investigator


HX 16-072 Determining and targeting reasons for low statin use to improve guideline-concordantstatin therapy in high-risk patients

S. Virani, MD, PhD – Principal Investigator; L. Martin, PhD - Co-Investigator; L. Petersen, MD, MPH - Co-Investigator; P. Richardson, PhD - Co-Investigator; R. Street, PhD - Co-Investigator

HSR&D $1,097,703


HX 15-438 Improving the Measurement of VA Facility Performance to Foster a Learning Healthcare System

L. Petersen, MD, MPH - Principal Investigator; S. Hysong, PhD - Co-Investigator

HSR&D $1,099,174


HX-16-025 Less is More: Improving Antimicrobial Stewardship for Asymptomatic Bacteriuria

B. Trautner, MD, PhD – Principal Investigator; L. Petersen, MD, MPH - Co-Investigator; S. Hysong, PhD - Co-Investigator; J. Kramer, PhD - Co-Investigator; A. Naik, MD - Co-Investigator

HSR&D $1,095,924


R01 Optimizing Alphafetoprotein as a Biomarker for Detecting Hepatocellular Carcinoma

J. Davila PhD MS BS - Co-Investigator

NIH NCI R01

$1,200,000


A Multi-level Intervention to Improve Cancer Care for Hepatocellular Carcinoma

J. Davila PhD MS BS - Principal Investigator

HSR&D $1,997,000


XXX XX-XXX

National Cancer Institute/Department of Veterans Affairs Big Data Fellowship in Cancer Research

J. Davila PhD MS BS - Co-Director

NCI/VA $40,000 10/1/2015 9/30/2018 Fellowship

XXX XX-XXX

QUERI-OAA Centers of Excellence in Primary Care Training Program: Participant Survey

J. Davila PhD MS BS - Principal Investigator

VA QUERI OAA

$50,000 10/1/2014 9/30/2018 Fellowship

XXX XX-XXX

Effectiveness of Zepatier™ (elbasvir (EBR)/grazoprevir (GZR)) co-administered with Ribavirin (RBV) treatment for 16 weeks duration in chronic hepatitis C virus (HCV) genotype 1a (GT1a)-infected patients with selected baseline NS5A resistance associated substitutions: A retrospective observational analysis of the US Veterans Health Administration (VHA) National Data

J. Kramer, PhD - Co-PI

Merck & Co

$261,903 1/1/2018 12/31/2018 Data Collection

CX 001430 Sex hormones and HCV-related liver disease progression

D. White, PhD - Principal Investigator

VA CSR&D

$950,000 7/1/2017 6/1/2021 Data Collection

CA 206479 Identifying Novel Pharmacologic Risk factors for Common Malignancies In Individuals with Well-controlled HIV Infection (PQ3)

D. White, PhD - Co-Investigator

NCI R01 $1,968,930


RP 150587 The Texas Hepatocellular consortium (THCCC)


CPRIT $9,771,157


CA 190776 A New Lab Based Algorithm for HCC Surveillance in Patients with Cirrhosis


NCI R01 $1,793,421


HS 025474 Engaging Patients in Diagnostic Error Reporting

T. Giardina, PhD – Principal Investigator; H. Singh, MD – Co-Investigator

AHRQ K01

$766,326 09/01/2018

08/31/2023 Data Collection

Hematology-Oncology


1

Section of Hematology/Oncology Department of Medicine, Baylor College of Medicine (1 July 2017–30 June 2018)

Faculty Caroline E. Arber Barth, MD Malcolm K. Brenner, MD George Carrum, MD Gary C. Chamness, MD Chad Creighton, MD Matthew Ellis, MD Suzanne Fuqua, MD Svasti Haricharan, MD Bin He, MD Valentina Hoyos, MD Sao Jiralerspong, MD Aparna C. Jotwani, MD Mamta Kalidas, MD Rammurti Kamble, MD Salma Kaochar, PhD Meghashyam Kavuri, MD Weei-Chin Lin, MD PhD Fang- Tsyr (Fannie) Lin, MD Premal Lulla, MD Maksim Mamonkin, MD Courtney N. Miller-Chism, MD Martha P. Mims, MD PhD Nicholas Mitsiades, MD PhD

Benjamin Musher, MD Julie Nangia, MD Charles K. Osborne, MD Carlos Ramos, MD Mothaffar F. Rimawi, MD Gustavo Rivero, MD Anita L. Sabichi, MD Yvonne Hsiao-Fan Sada, MD Rachel Schiff, MD Brandon G Smaglo, MD, FACP Iberia Romina Sosa, MD PhD Samer Srour, MD, MB, ChB, MS Sravanti P. Teegavarapu, MD Perumal Thiagarajan, MD Mark M. Udden, MD Juan Fernando Vera Valdes, MD Ayumi Watanabe, MD Zahida Yasin, MD Sarvari V.Yellapragada, MD Aihua E.Yen, MD Jun Zhang, MD

2

Contents A. Publications ................................................................................................................... 3 B. Awards and Honors ......................................................................................................11 C. Books and Book Chapters ............................................................................................12 D. Professional Organization/Association Offices Held 12 E. Editorial Board Memberships and Editorial Positions ....................................................13 F. Grants ...........................................................................................................................14 G. Cash Rewards…………………………………………………………………………….……18

3

A. Publications 1. Young M, Dahoun T, Sokrat B, Arber C, Chen KM, Bouvier M, Barth P. Computational

design of orthogonal membrane receptor-effector switches for rewiring signaling pathways. Proc Natl Acad Sci U S A. 2018 Jul 3;115(27):7051-7056. doi: 10.1073/pnas.1718489115. Epub 2018 Jun 18.PMID:29915030

2. Arber C, Young M, Barth P. Reprogramming cellular functions with engineered membrane

proteins. Curr Opin Biotechnol. 2017 Oct;47:92-101. doi: 10.1016/j.copbio.2017.06.009. Epub 2017 Jul 11. Review.PMID:28709113

3. Brenner MK.Onward and upward for immuno-oncology. Chin Clin Oncol. 2018 Apr;7(2):18. PMID:29764163

4. Yanir AD, Hanson IC, Shearer WT, Noroski LM, Forbes LR, Seeborg FO, Nicholas S,

Chinn I, Orange JS, Rider NL, Leung KS, Naik S, Carrum G, Sasa G, Hegde M, Omer BA, Ahmed N, Allen CE, Khaled Y, Wu MF, Liu H, Gottschalk SM, Heslop HE, Brenner MK, Krance RA, Martinez CA. High Incidence of Autoimmune Disease after Hematopoietic Stem Cell Transplantation for Chronic Granulomatous Disease..Biol Blood Marrow Transplant. 2018 Apr 6. pii: S1083-8791(18)30163-0. PMID: 29630926

5. Bollard CM, Tripic T, Cruz CR, Dotti G, Gottschalk S, Torrano V, Dakhova O, Carrum G,

Ramos CA, Liu H, Wu MF, Marcogliese AN, Barese C, Zu Y, Lee DY, O'Connor O, Gee AP, Brenner MK, Heslop HE, Rooney CM. Tumor-Specific T-Cells Engineered to Overcome Tumor Immune Evasion Induce Clinical Responses in Patients With Relapsed Hodgkin Lymphoma..J Clin Oncol. 2018 Apr 10;36(11):1128-1139.PMID 29315015

6. Tzannou I, Papadopoulou A, Naik S, Leung K, Martinez CA, Ramos CA, Carrum G, Sasa

G, Lulla P, Watanabe A, Kuvalekar M, Gee AP, Wu MF, Liu H, Grilley BJ, Krance RA, Gottschalk S, Brenner MK, Rooney CM, Heslop HE, Leen AM, Omer B. Off-the-Shelf Virus-Specific T Cells to Treat BK Virus, Human Herpesvirus 6, Cytomegalovirus, Epstein-Barr Virus, and Adenovirus Infections After Allogeneic Hematopoietic Stem-Cell Transplantation..J Clin Oncol. 2017 Nov 1;35(31):3547-3557. PMID:28783452

7. Kapke JT, Epperla N, Shah N, Richardson K, Carrum G, Hari PN, Pingali SR, Hamadani

M, Karmali R, Fenske TS. Effect of Routine Surveillance Imaging on the Outcomes of Patients With Classical Hodgkin Lymphoma After Autologous Hematopoietic Cell Transplantation. Clin Lymphoma Myeloma Leuk. 2017 Jul;17(7):408-414. PMID:28756899

8. Xu X, De Angelis C, Burke KA, Nardone A, Hu H, Qin L, Veeraraghavan J, Sethunath V,

Heiser LM, Wang N, Ng CKY, Chen ES, Renwick A, Wang T, Nanda S, Shea M, Mitchell T, Rajendran M, Waters I, Zabransky DJ, Scott KL, Gutierrez C, Nagi C, Geyer FC, Chamness GC, Park BH, Shaw CA, Hilsenbeck SG, Rimawi MF, Gray JW, Weigelt B, Reis-Filho JS, Osborne CK, Schiff R. HER2 Reactivation through Acquisition of the HER2 L755S Mutation as a Mechanism of Acquired Resistance to HER2-targeted Therapy in HER2+ Breast Cancer. Clin Cancer Res. 2017 Sep 1;23(17):5123-5134. PMID:28487443

9. Tan X, Banerjee P, Liu X, Yu J, Gibbons DL, Wu P, Scott KL, Diao L, Zheng X, Wang J,

Jalali A, Suraokar M, Fujimoto J, Behrens C, Liu X, Liu CG, Creighton CJ, Wistuba II,

https://www.ncbi.nlm.nih.gov/pubmed/28709113


















4

Kurie JM. The epithelial-to-mesenchymal transition activator ZEB1 initiates a prometastatic competing endogenous RNA network..J Clin Invest. 2018 Jul 2;128(7):3198. doi: 10.1172/JCI122740. Epub 2018 Jul 2. No abstract available. PMID:30108197

10. Kundu ST, Grzeskowiak CL, Fradette JJ, Gibson LA, Rodriguez LB, Creighton CJ, Scott

KL, Gibbons DL. TMEM106B drives lung cancer metastasis by inducing TFEB-dependent lysosome synthesis and secretion of cathepsins..Nat Commun. 2018 Jul 16;9(1):2731. PMID:30013069

11. You R, DeMayo FJ, Liu J, Cho SN, Burt BM, Creighton CJ, Casal RF, Lazarus DR, Lu W,

Tung HY, Yuan X, Hill-McAlester A, Kim M, Perusich S, Cornwell L, Rosen D, Song LZ, Paust S, Diehl G, Corry D, Kheradmand F. IL17A Regulates Tumor Latency and Metastasis in Lung Adeno and Squamous SQ.2b and AD.1 Cancer. Cancer Immunol Res. 2018 Jun;6(6):645-657. PMID:29653981

12. Haricharan S, Punturi N, Singh P, Holloway KR, Anurag M, Schmelz J, Schmidt C, Lei JT,

Suman V, Hunt K, Olson JA Jr, Hoog J, Li S, Huang S, Edwards DP, Kavuri SM, Bainbridge MN, Ma CX, Ellis MJ .Loss of MutL Disrupts CHK2-Dependent Cell-Cycle Control through CDK4/6 to Promote Intrinsic Endocrine Therapy Resistance in Primary Breast Cancer. Cancer discovery. 2017; 7(10):1168-1183. PMID:28801307

13. Nair A, Chung HC, Sun T, Tyagi S, Dobrolecki LE, Dominguez-Vidana R, Kurley SJ,

Orellana M, Renwick A, Henke DM, Katsonis P, Schmitt E, Chan DW, Li H, Mao S, Petrovic I, Creighton CJ, Gutierrez C, Dubrulle J, Stossi F, Tyner JW, Lichtarge O, Lin CY, Zhang B, Scott KL, Hilsenbeck SG, Sun J, Yu X, Osborne CK, Schiff R, Christensen JG, Shields DJ, Rimawi MF, Ellis MJ, Shaw CA, Lewis MT, Westbrook TF. Combinatorial inhibition of PTPN12-regulated receptors leads to a broadly effective therapeutic strategy in triple-negative breast cancer. Nature medicine. 2018; 24(4):505-511. PMID:29578538

14. Huang KL, Li S, Mertins P, Cao S, Gunawardena HP, Ruggles KV, Mani DR, Clauser KR,

Tanioka M, Usary J, Kavuri SM, Xie L, Yoon C, Qiao JW, Wrobel J, Wyczalkowski MA, Erdmann-Gilmore P, Snider JE, Hoog J, Singh P, Niu B, Guo Z, Sun SQ, Sanati S, Kawaler E, Wang X, Scott A, Ye K, McLellan MD, Wendl MC, Malovannaya A, Held JM, Gillette MA, Fenyö D, Kinsinger CR, Mesri M, Rodriguez H, Davies SR, Perou CM, Ma C, Reid Townsend R, Chen X, Carr SA, Ellis MJ, Ding L. Proteogenomic integration reveals therapeutic targets in breast cancer xenografts. Nature communications. 2017; 8:14864. PMID: 28348404

15. Baker A, Wyatt D, Bocchetta M, Li J, Filipovic A, Green A, Peiffer DS, Fuqua S, Miele L,

Albain KS, Osipo C.Notch-1-PTEN-ERK1/2 signaling axis promotes HER2+ breast cancer cell proliferation and stem cell survival. Oncogene. 2018 May 10. doi: 10.1038/s41388-018-0251-y. [Epub ahead of print]PMID:29743588

16. Zhang Z, Nikolai BC, Gates LA, Jung SY, Siwak EB, He B, Rice AP, O'Malley BW, Feng Q.

Crosstalk between histone modifications indicates that inhibition of arginine methyltransferase CARM1 activity reverses HIV latency. Nucleic Acids Res. 2017 Sep 19;45(16):9348-9360 PMID: 28637181

17. Kaochar S, Mitsiades N. A Novel Mechanism to Drive Castration-Resistant Prostate

Cancer. Trends Endocrinol Metab. 2018 Jun;29(6):366-368. PMID:29605661











5

18. Kaochar S, Dong J, Torres M, Rajapakshe K, Nikolos F, Davis CM, Ehli EA, Coarfa C, Mitsiades N, Poulaki V. ICG-001 Exerts Potent Anticancer Activity Against Uveal Melanoma Cells. Invest Ophthalmol Vis Sci. 2018 Jan 1;59(1):132-143. PMID:29332125

19. Chinn IK, Eckstein OS, Peckham-Gregory EC, Goldberg BR, Forbes LR, Nicholas SK, Mace EM, Vogel TP, Abhyankar HA, Diaz MI, Heslop HE, Krance RA, Martinez CA, Nguyen TC, Bashir DA, Goldman JR, Stray-Pedersen A, Pedroza LA, Poli MC, Aldave-Becerra JC, McGhee SA, Al-Herz W, Chamdin A, Coban-Akdemir ZH, Jhangiani SN, Muzny DM, Cao TN, Hong DN, Gibbs RA, Lupski JR, Orange JS, McClain KL, Allen CE. Genetic and mechanistic diversity in pediatric hemophagocytic lymphohistiocytosis. Blood. 2018 Jul 5;132(1):89-100. PMID: 29632024

20. Heslop HE, Brenner MK. Seek and You Will Not Find: Ending the Hunt for Replication-

Competent Retroviruses during Human Gene Therapy. Mol Ther. 2018 Jan 3;26(1):1-2. PMID:29273500

21. Ngwube A, Hanson IC, Orange J, Rider NL, Seeborg F, Shearer W, Noroski L, Nicholas

S, Forbes L, Leung K, Sasa G, Naik S, Hegde M, Omer B, Ahmed N, Allen C, Gottschalk S, Wu MF, Liu H, Brenner M, Heslop H, Krance R, Martinez C. Outcomes after Allogeneic Transplant in Patients with Wiskott-Aldrich Syndrome. Biol Blood Marrow Transplant. 2018 Mar;24(3):537-541. PMID: 29196075

22. Heczey A, Louis CU, Savoldo B, Dakhova O, Durett A, Grilley B, Liu H, Wu MF, Mei Z,

Gee A, Mehta B, Zhang H, Mahmood N, Tashiro H, Heslop HE, Dotti G, Rooney CM, Brenner MK. CAR T Cells Administered in Combination with Lymphodepletion and PD-1 Inhibition to Patients with Neuroblastoma. Mol Ther. 2017 Sep 6;25(9):2214-2224 PMID: 28602436

23. Ahmed N, Brawley V, Hegde M, Bielamowicz K, Kalra M, Landi D, Robertson C, Gray TL,

Diouf O, Wakefield A, Ghazi A, Gerken C, Yi Z, Ashoori A, Wu MF, Liu H, Rooney C, Dotti G, Gee A, Su J, Kew Y, Baskin D, Zhang YJ, New P, Grilley B, Stojakovic M, Hicks J, Powell SZ, Brenner MK, Heslop HE, Grossman R, Wels WS, Gottschalk S.

HER2-Specific Chimeric Antigen Receptor-Modified Virus-Specific T Cells for Progressive Glioblastoma: A Phase 1 Dose-Escalation Trial. JAMA Oncol. 2017 Aug 1;3(8):1094-1101. PMID: 28426845 24. Liu K, Lin F-T, Graves JD, Lee T-J and Lin W-C. Mutant p53 perturbs replication

checkpoint response through TopBP1 and Treslin. Proc. Natl. Acad. Sci., USA, 2017; 114(19):E3766-E3775. PMID: 28439015.

25. Lulla PD, Hill LC, Ramos CA, Heslop HE. The use of chimeric antigen receptor T cells in patients with non-Hodgkin lymphoma. Clin Adv Hematol Oncol. 2018 May;16(5):375-386.PMID:29851933

26. Bajgain P, Tawinwung S, D'Elia L, Sukumaran S, Watanabe N, Hoyos V, Lulla P, Brenner

MK, Leen AM, Vera JF. CAR T cell therapy for breast cancer: harnessing the tumor milieu to drive T cell activation. J Immunother Cancer. 2018 May 10;6(1):34PMID:29747685

27. Tzannou I, Nicholas SK, Lulla P, Aguayo-Hiraldo PI, Misra A, Martinez CA, Machado AA,

Orange JS, Piedra PA, Vera JF, Leen AM.Immunologic Profiling of Human















6

Metapneumovirus for the Development of Targeted Immunotherapy. J Infect Dis. 2017 216(6):678-687. PMID:28934427

28. Aguayo-Hiraldo PI, Arasaratnam RJ, Tzannou I, Kuvalekar M, Lulla P, Naik S, Martinez

CA, Piedra PA, Vera JF, Leen AM. Characterizing the Cellular Immune Response to Parainfluenza Virus 3. J Infect Dis. 2017 Jul 15;216(2):153-161. PMID:28472480

29. Mamonkin M, Mukherjee M, Srinivasan M, Sharma S, Gomes-Silva D, Mo F, Krenciute G,

Orange JS, Brenner MK. Reversible Transgene Expression Reduces Fratricide and Permits 4-1BB Costimulation of CAR T Cells Directed to T-cell Malignancies. Cancer Immunol Res. 2018 Jan;6(1):47-58. PMID:29079655

30. Dong J, Wong LJ, Mims MP. Mitochondrial inheritance and cancer. Transl Res. 2018 Jun

25. pii: S1931-5244(18)30100-2. doi: 10.1016/j.trsl.2018.06.004. [Epub ahead of print] Review. PMID: 30044960

31. Flaig TW, Plets M, Hussain MHA, Agarwal N, Mitsiades N, Deshpande HA, Vaishampayan UN, Thompson IM Jr. Abiraterone Acetate for Metastatic Prostate Cancer in Patients With Suboptimal Biochemical Response to Hormone Induction. JAMA Oncol. 2017 Nov 9;3(11):e170231. PMID: 28358937

32. Geng C, Kaochar S, Li M, Rajapakshe K, Fiskus W, Dong J, Foley C, Dong D, Zhang L, Kwon OJ, Shah S, Bolaki M, Xin L, Ittmann M, O'Malley BW, Coarfa C, Mitsiades N. SPOP regulates prostate epithelial cell proliferation and promotes ubiquitination and turnover of cMYC oncoprotein. Oncogene 2017 Aug 17;36(33):4767-4777. PMID:28414305

33. Date RC, Adams MK, Teh BS, Schefler AC, Musher BL, Farach A, Weng CY A rare

presentation of choroidal metastasis from primary esophageal adenocarcinoma successfully treated with intensity-modulated radiation therapy.. Am J Ophthalmol Case Rep. 2018 Apr 23;11:19-22. PMID: 30057967

34. Balasubramanyam S, O'Donnell BP, Musher BL, Jhaveri PM, Ludwig MS Evaluating

Treatment Patterns for Small Cell Carcinoma of the Colon Using the National Cancer Database (NCDB). J Gastrointest Cancer. 2018 Jan 22. doi: 10.1007/s12029-018-0054-y. [Epub ahead of print] PMID:29354876

35. Thyparampil PJ, Yen MT, Dhingra S, Shetlar DJ, Zarrin-Khameh N, Musher BL. Primary

Neuroendocrine Tumor of the Orbit Presenting With Acute Proptosis. Ophthalmic Plast Reconstr Surg. 2018 Jan/Feb;34(1):e17-e19. PMID:28746252

36. Barnes JA, Ellis ML, Hwang S, Emarine J, Merwin P, Salinas GD, Musher BL.

Identification of Educational Gaps Among Oncologists Who Manage Patients with Pancreatic Cancer. J Gastrointest Cancer. 2017 Nov 27. doi: 10.1007/s12029-017-0033-8. [Epub ahead of print] PMID:29177608

37. Freites-Martinez A, Shapiro J, Goldfarb S, Nangia J, Jimenez JJ, Paus R, Lacouture ME.

CME Part 1: Hair disorders in cancer patients.J Am Acad Dermatol. 2018 Apr 13. pii: S0190-9622(18)30529-2. PMID:29660422




















7

38. Nangia J. Quality of Life Matters: It Is Time to Integrate Scalp Cooling in Routine Clinical Practice.J Oncol Pract. 2018 Mar;14(3):157-158. PMID:29529388

39. Gomes-Silva D, Ramos CA. Cancer Immunotherapy Using CAR-T Cells: From the

Research Bench to the Assembly Line.Biotechnol J. 2018 Feb;13(2). doi: 10.1002/biot.201700097. Epub 2017 Oct 30. Review.PMID:28960810

40. Ramos CA, Ballard B, Zhang H, Dakhova O, Gee AP, Mei Z, Bilgi M, Wu M, Liu H, Grilley

B, Bollard C, Chang BH, Rooney CM, Brenner MK, Heslop H, Dotti G, Savoldo B (2017) – Clinical and immunological responses after CD30-specific chimeric antigen receptor-redirected lymphocytes. The Journal of Clinical Investigation. 127:3462-71 PMID:28805662

41. Tzannou I, Papadopoulou A, Naik S, Leung K, Martinez CA, Ramos CA, Carrum G, Sasa

G, Lulla P, Watanabe A, Kuvalekar M, Gee AP, Wu MF, Liu H, Grilley BJ, Krance RA, Gottschalk S, Brenner MK, Rooney CM, Heslop HE, Leen AM, Omer B (2017) – Off-the-Shelf Virus-Specific T Cells to Treat BK Virus, Human Herpesvirus 6, Cytomegalovirus, Epstein-Barr Virus, and Adenovirus Infections After Allogeneic Hematopoietic Stem-Cell Transplantation. Journal of Clinical Oncology. 35:3547-57. PMID: 28783452

42. Wapnir IL, Price KN, Anderson SJ, Robidoux A, Martín M, Nortier JWR, Paterson AHG,

Rimawi MF, Láng I, Baena-Cañada JM, Thürlimann B, Mamounas EP, Geyer CE Jr, Gelber S, Coates AS, Gelber RD, Rastogi P, Regan MM, Wolmark N, Aebi S; International Breast Cancer Study Group; NRG Oncology, GEICAM Spanish Breast Cancer Group, BOOG Dutch Breast Cancer Trialists' Group; Breast International Group. Efficacy of Chemotherapy for ER-Negative and ER-Positive Isolated Locoregional Recurrence of Breast Cancer: Final Analysis of the CALOR Trial..J Clin Oncol. 2018 Apr 10;36(11):1073-1079. PMID:29443653

43. Chang E, Rivero G, Patel NR, Chiao EY, Lai S, Bajaj K, Mbue JE, Yellapragada SV. HIV-

related Refractory Hodgkin Lymphoma: A Case Report of Complete Response to Nivolumab. Clin Lymphoma Myeloma Leuk. 2018 Feb;18(2):e143-e146. PMID:29342442

44. Chang E, Sabichi AL, Kramer JR, Hartman C, Royse KE, White DL, Patel NR, Richardson

P, Yellapragada SV, Garcia JM, Chiao EY. Nivolumab Treatment for Cancers in the HIV-infected Population. J Immunother. 2018 Jul 16. doi: 10.1097/CJI.0000000000000240. [Epub ahead of print] PMID:30020193

45. Sada YH, Tran Cao HS, Chang GJ, Artinyan A, Musher BL, Smaglo BG, Massarweh NN.

Prognostic value of neoadjuvant treatment response in locally advanced rectal cancer.J Surg Res. 2018 Jun;226:15-23 PMID: 29661280

46. Zou WY, El-Serag HB, Sada YH, Temple SL, Sansgiry S, Kanwal F, Davila JA

Determinants and Outcomes of Hospice Utilization Among Patients with Advance-Staged Hepatocellular Carcinoma in a Veteran Affairs Population.. Dig Dis Sci. 2018 May;63(5):1173-1181. PMID:29508165

47. Tran Cao HS, Zhang Q, Sada YH, Chai C, Curley SA, Massarweh NN. The role of surgery

and adjuvant therapy in lymph node-positive cancers of the gallbladder and intrahepatic bile ducts. Cancer. 2018 Jan 1;124(1):74-83. PMID:28841223



















8

48. Tran Cao HS, Zhang Q, Sada YH, Silberfein EJ, Hsu C, Van Buren G 2nd, Chai C, Katz MHG, Fisher WE, Massarweh NN. Value of lymph node positivity in treatment planning for early stage pancreatic cancer. Surgery. 2017 Sep;162(3):557-567. PMID:28666686

49. Mason MC, Chang GJ, Petersen LA, Sada YH, Tran Cao HS, Chai C, Berger DH,

Massarweh NN. National Quality Forum Colon Cancer Quality Metric Performance: How Are Hospitals Measuring Up? Ann Surg. 2017 Dec;266(6):1013-1020. PMID:27617852

50. Giuliano M, Shaikh A, Lo HC, Arpino G, De Placido S, Zhang XH, Cristofanilli M, Schiff R,

Trivedi MV. Perspective on Circulating Tumor Cell Clusters: Why It Takes a Village to Metastasize. Cancer Res. 2018 Feb 15;78(4):845-852. PMID:29437766

51. Wu Y, Zhang Z, Cenciarini ME, Proietti CJ, Amasino M, Hong T, Yang M, Liao Y, Chiang

HC, Kaklamani VG, Jeselsohn R, Vadlamudi RK, Huang TH, Li R, De Angelis C, Fu X, Elizalde PV, Schiff R, Brown M, Xu K. Tamoxifen Resistance in Breast Cancer Is Regulated by the EZH2-ERα-GREB1 Transcriptional Axis.Cancer Res. 2018 Feb 1;78(3):671-684. PMID:29212856

52. Ito K, Park SH, Katsyv I, Zhang W, De Angelis C, Schiff R, Irie HY. PTK6 regulates growth

and survival of endocrine therapy-resistant ER+ breast cancer cells..NPJ Breast Cancer. 2017 Nov 17;3:45. doi: 10.1038/s41523-017-0047-1. eCollection 2017.PMID:29167821

53. Deeken JF, Wang H, Hartley M, Cheema AK, Smaglo B, Hwang JJ, He AR, Weiner LM,

Marshall JL, Giaccone G, Liu S, Luecht J, Spiegel JY, Pishvaian MJ. A phase I study of intravenous artesunate in patients with advanced solid tumor malignancies. Cancer Chemother Pharmacol. 2018 Mar;81(3):587-596. PMID:29392450

54. Quadri HS, Smaglo BG, Morales SJ, Phillips AC, Martin AD, Chalhoub WM, Haddad NG,

Unger KR, Levy AD, Al-Refaie WB. Gastric Adenocarcinoma: A Multimodal Approach. Front Surg. 2017 Aug 3;4:42. doi: 10.3389/fsurg.2017.00042. eCollection 2017. Review. PMID:28824918

55. Srour SA, Lee HJ, Nomie K, Ye H, Chen W, Oriabure O, Romaguera J, Wang ML. Novel chemotherapy-free combination regimen for ibrutinib-resistant mantle cell lymphoma. Br J Haematol. 2018 May;181(4):561-564. dPMID:28369820

56. Jain P, Romaguera J, Srour SA, Lee HJ, Hagemeister F, Westin J, Fayad L, Samaniego

F, Badillo M, Zhang L, Nastoupil L, Kanagal-Shamanna R, Fowler N, Wang ML. Four-year follow-up of a single arm, phase II clinical trial of ibrutinib with rituximab (IR) in patients with relapsed/refractory mantle cell lymphoma (MCL).Clin Lymphoma Myeloma Leuk. 2017 Jul;17(7):450-456. PMID:29785709

57. Srour SA, Machiorlatti M, Pierson NT, Bhutta UZ, Cherry M, Selby GB, Thompson DM, Vesely SK, Kurkjian CD. Impact of Health Care Insurance Status on Treatment Outcomes of Acute Myeloid Leukemia. Clin Lymphoma Myeloma Leuk. 2017 Jul;17(7):450-456. PMID:28624543

58. Srour SA, Li S, Popat UR, Qazilbash MH, Lozano-Cerrada S, Maadani F, Alousi A,





















9

Kebriaei P, Anderlini P, Nieto Y, Jones R, Shpall E, Champlin RE, Hosing C. A randomized phase II study of standard-dose versus high-dose rituximab with BEAM in autologous stem cell transplantation for relapsed aggressive B-cell non-hodgkin lymphomas: long term results. Br J Haematol. 2017 Aug;178(4):561-570. PMID:28485023

59. Wu Y, Liu W, Zhou Y, Hilton T, Zhao Z, Liu W, Wang M, Yeon J, Houck K, Thiagarajan P,

Zhang F, Shi FD, Wu X, Li M, Dong JF, Zhang J. Von Willebrand factor enhanced microvesicle-induced vascular leakage and coagulopathy in mice with traumatic brain injury. Blood. 2018 Jun 25. pii: blood-2018-03-841932. doi: 10.1182/blood-2018-03-841932. [Epub ahead of print] PMID:29941674

60. Zhou Y, Cai W, Zhao Z, Hilton T, Wang M, Yeon J, Liu W, Zhang F, Shi FD, Wu X,

Thiagarajan P, Li M, Zhang J, Dong JF. Lactadherin promotes microvesicle clearance to prevent coagulopathy and improves survival of severe TBI mice. Blood. 2018 Feb 1;131(5):563-572. PMID:29162596

61. Bajgain P, Tawinwung S, D'Elia L, Sukumaran S, Watanabe N, Hoyos V, Lulla P,

Brenner MK, Leen AM, Vera JF. CAR T cell therapy for breast cancer: harnessing the tumor milieu to drive T cell activation. J Immunother Cancer. 2018 May 10;6(1):34. PMID:29747685

62. Kumar AJ, Kim S, Hemmer MT, Arora M, Spellman SR, Pidala JA, Couriel DR, Alousi AM,

Aljurf MD, Cahn JY, Cairo MS, Cutler CS, Farhan S, Gergis U, Hale GA, Hashmi SK, Inamoto Y, Kamble RT, Kharfan-Dabaja MA, MacMillan ML, Marks DI, Nakasone H, Norkin M, Qayed M, Ringden O, Schouten HC, Schultz KR, Solh MM, Teshima T, Urbano-Ispizua A, Verdonck LF, Gale RP, Hamilton BK, Majhail NS, Loren AW. Graft-versus-host disease in recipients of male unrelated donor compared with parous female sibling donor transplants. Blood Adv. 2018 May 8;2(9):1022-1031. PMID:29739773

63. Strati P, Chihara D, Oki Y, Fayad LE, Fowler N, Nastoupil L, Romaguera JE, Samaniego F,

Garg N, Feng L, Wesson ET, Ruben CE, Stafford MD, Nieto Y, Khouri IF, Hosing C, Horowitz SB, Kamble RT, Fanale MA. A phase I study of romidepsin and ifosfamide, carboplatin, etoposide for the treatment of patients with relapsed or refractory peripheral T-cell lymphoma. Haematologica. 2018 Apr 5. pii: haematol.2018.187617. PMID: 29622656

64. Wood WA, Brazauskas R, Hu ZH, Abdel-Azim H, Ahmed IA, Aljurf M, Badawy S,

Beitinjaneh A, George B, Buchbinder D, Cerny J, Dedeken L, Diaz MA, Freytes CO, Ganguly S, Gergis U, Almaguer DG, Gupta A, Hale G, Hashmi SK, Inamoto Y, Kamble RT, Adekola K, Kindwall-Keller T, Knight J, Kumar L, Kuwatsuka Y, Law J, Lazarus HM, LeMaistre C, Olsson RF, Pulsipher MA, Savani BN, Schultz KR, Saad AA, Seftel M, Seo S, Shea TC, Steinberg A, Sullivan K, Szwajcer D, Wirk B, Yared J, Yong A, Dalal J, Hahn T, Khera N, Bonfim C, Atsuta Y, Saber W. Country-Level Macroeconomic Indicators Predict Early Post-Allogeneic Hematopoietic Cell Transplantation Survival in Acute Lymphoblastic Leukemia: A CIBMTR Analysis. Biol Blood Marrow Transplant. 2018 Mar 19. pii: S1083-8791(18)30129-0 PMID:29567340

65. Turcotte LM, Wang T, Hemmer MT, Spellman SR, Arora M, Couriel D, Alousi A, Pidala J,

Abdel-Azim H, Ahmed I, Beitinjaneh A, Buchbinder D, Byrne M, Callander N, Chao N, Choi SW, DeFilipp Z, Gadalla SM, Gale RP, Gergis U, Hashmi S, Hematti P, Holmberg L,





















10

Inamoto Y, Kamble RT, Lehmann L, MacMillan MA, McIver Z, Nishihori T, Norkin M, O'Brien T, Olsson RF, Reshef R, Saad A, Savani BN, Schouten HC, Seo S, Solh M, Verdonck L, Vij R, Wirk B, Yared J, Horowitz MM, Knight JM, Verneris MR. Donor body mass index does not predict graft versus host disease following hematopoietic cell transplantation. Bone Marrow Transplant. 2018 Jul;53(7):932-937. PMID:29382954

66. Casulo C, Friedberg JW, Ahn KW, Flowers C, DiGilio A, Smith SM, Ahmed S, Inwards D,

Aljurf M, Chen AI, Choe H, Cohen J, Copelan E, Farooq U, Fenske TS, Freytes C, Gaballa S, Ganguly S, Jethava Y, Kamble RT, Kenkre VP, Lazarus H, Lazaryan A, Olsson RF, Rezvani AR, Rizzieri D, Seo S, Shah GL, Shah N, Solh M, Sureda A, William B, Cumpston A, Zelenetz AD, Link BK, Hamadani M. Autologous Transplantation in Follicular Lymphoma with Early Therapy Failure: A National LymphoCare Study and Center for International Blood and Marrow Transplant Research Analysis. Biol Blood Marrow Transplant. 2018 Jun;24(6):1163-1171. PMID: 29242111

67. Qayed M, Wang T, Hemmer MT, Spellman S, Arora M, Couriel D, Alousi A, Pidala J, Abdel-Azim H, Aljurf M, Ayas M, Bitan M, Cairo M, Choi SW, Dandoy C, Delgado D, Gale RP, Hale G, Frangoul H, Kamble RT, Kharfan-Dabaja M, Lehman L, Levine J, MacMillan M, Marks DI, Nishihori T, Olsson RF, Hematti P, Ringden O, Saad A, Satwani P, Savani BN, Schultz KR, Seo S, Shenoy S, Waller EK, Yu L, Horowitz MM, Horan J. Influence of Age on Acute and Chronic GVHD in Children Undergoing HLA-Identical Sibling Bone Marrow Transplantation for Acute Leukemia: Implications for Prophylaxis. Biol Blood Marrow Transplant. 2018 Mar;24(3):521-528. PMID: 29155316

68. Arnold SD, Brazauskas R, He N, Li Y, Aplenc R, Jin Z, Hall M, Atsuta Y, Dalal J, Hahn T,

Khera N, Bonfim C, Majhail NS, Diaz MA, Freytes CO, Wood WA, Savani BN, Kamble RT, Parsons S, Ahmed I, Sullivan K, Beattie S, Dandoy C, Munker R, Marino S, Bitan M, Abdel-Azim H, Aljurf M, Olsson RF, Joshi S, Buchbinder D, Eckrich MJ, Hashmi S, Lazarus H, Marks DI, Steinberg A, Saad A, Gergis U, Krishnamurti L, Abraham A, Rangarajan HG, Walters M, Lipscomb J, Saber W, Satwani P. Clinical risks and healthcare utilization of hematopoietic cell transplantation for sickle cell disease in the USA using merged databases. Haematologica. 2017 Nov;102(11):1823-1832. PMID: 28818869

69. Gabriel M, Shaw BE, Brazauskas R, Chen M, Margolis DA, Sengelov H, Dahlberg A,

Ahmed IA, Delgado D, Lazarus HM, Gibson B, Myers KC, Kamble RT, Abdel-Mageed A, Li CK, Flowers MED, Battiwalla M, Savani BN, Majhail N, Shaw PJ. Risk Factors for Subsequent Central Nervous System Tumors in Pediatric Allogeneic Hematopoietic Cell Transplant: A Study from the Center for International Blood and Marrow Transplant Research (CIBMTR). Biol Blood Marrow Transplant. 2017 Aug;23(8):1320-1326 PMID:28411175

70. Vrooman LM, Millard HR, Brazauskas R, Majhail NS, Battiwalla M, Flowers ME, Savani

BN, Akpek G, Aljurf M, Bajwa R, Baker KS, Beitinjaneh A, Bitan M, Buchbinder D, Chow E, Dandoy C, Dietz AC, Diller L, Gale RP, Hashmi SK, Hayashi RJ, Hematti P, Kamble RT, Kasow KA, Kletzel M, Lazarus HM, Malone AK, Marks DI, O'Brien TA, Olsson RF, Ringden O, Seo S, Steinberg A, Yu LC, Warwick A, Shaw B, Duncan C. Survival and Late Effects after Allogeneic Hematopoietic Cell Transplantation for Hematologic Malignancy at Less than Three Years of Age. Biol Blood Marrow Transplant. 2017 Aug;23(8):1327-1334. doi: 10.1016/j.bbmt.2017.04.017. Epub 2017 Apr 28. PMID: 28461213




















11

B. Awards and Honors 1. Brenner: European Society of Gene and Cell Therapy Outstanding Achievement

Award[ 2. Ellis: Forbes Physician Honor Roll December 2017 3. Kaochar: American Association of Cancer Research (AACR) Prostate 2017 Scholar-

in-Training Award American Association of Cancer Research (AACR) Women in Cancer Research Award 2018 Prostate Cancer Foundation Young Investigator Award

4. Heslop: President American Society of Gene and Cell Therapy 5. Lulla: ASH Scholar Award 2017 6. Miller-Chism: ASH Medical Educators Institute Scholar

Baylor Oncology Fellowship; Best Clinic Experience Teaching of the Year, for Hematology Clinic; 2017/18

7. Mims: Houstonia Magazine Top Doctor Baylor Oncology Fellowship; Best Clinic Experience Teaching of the Year, for Hematology Clinic; 2017/18

8. Musher: “Top Doctor” Harris Health System Baylor Oncology Fellowship; Best Clinic Experience Teaching of the Year, for GI Oncology Clinic; 2017/18 Houstonia Magazine Top Doctor

9. Nangia: Oncology Times Honorable Mention for Study Validating Safety and Efficacy of Scalp Cooling Technology

10. Osborne: 2018 AACR Distinguished Award for Extraordinary Scientific Achievement and Leadership in Breast Cancer Research.

11. Rivero: Center of Excellence in Healthy Equity, Training, and Research (COE) Junior Faculty Scholar 2017-2018 Cohort

12. Sabichi: Castle Connolly Top Doctors: 2017 13. Sada: Early Career Faculty Award for Excellence in Patient Care 14. Smaglo: Baylor Oncology Fellowship; Best Clinic Experience Teaching of the Year,

for GI Oncology Clinic; 2017/18 Duncan Cancer Center Early Phase Clinical Research Award

15. Sosa: That’s The Way Player of the Month Award: Center of Excellence in Healthy Equity, Training, and Research (COE) Junior Faculty Scholar 2018-2019 Cohort

16. Udden: Chair, American Board of Internal Medicine Hematology Board Baylor Oncology Fellowship; Best Clinic Experience Teaching of the Year, for Hematology Clinic; 2017/18

17. Yellapragada: Star Faculty Award for Excellence in Patient Care Baylor Hematology Fellows Award for Teaching in Hematology

https://en.wikipedia.org/wiki/European_Society_of_Gene_and_Cell_Therapy

https://en.wikipedia.org/wiki/Malcolm_Brenner#cite_note-5

12

C. Books and Book Chapters

D. Professional Organization/Association Offices Held 1. Heslop, H:

American Society of Gene and Cell therapy President American Society of Hematology Member, Nominating Committee Foundation for Accreditation of Cell Therapy President

2. Miller-Chism, C: American Society of Hematology

Medical Medical Educators Institute Member, Question writing committee for ASH SAP

3. Mims, M: American Society of Hematology Member, ASH Committee on Training Chair, ASH Training Awards Committee Chair, ASH Research Training Award for Fellows Study Section Director K2R Program for ASH Member ASH Awards Committee; Member ASH Ambassador Program Faculty

1. M. P. Mims (2017) Thromboembolic Disease in Critical Care Obstetrics, Sixth Edition edited by Critical Care Obstetrics, 5th edition. Edited by M. Belfort, G. Saade, M. Foley, J. Phelan and G. Dildy. Blackwell Publishing Ltd.

2. R. Yates and M. Mims (2017) Testicular Cancer: Nonseminomatous Germ Cell Tumors:

Early Stage, Late Stage in Handbook of Prostate Cancer and Other Genitourinary Malignancies. (2017) (editors: Teresa G Hayes, MD, PhD, Martha Mims, MD, PhD, Jennifer Taylor, MD). Demos Medical Publishing, New York, New York.

3. G. Kang and M. Mims (2017) Testicular Cancer: Controversies in Management in

Handbook of Prostate Cancer and Other Genitourinary Malignancies. (2017) (editors: Teresa G Hayes, MD, PhD, Martha Mims, MD, PhD, Jennifer Taylor, MD). Demos Medical Publishing, New York, New York.

4. R. Sosa, and M.Udden (2017). Critical Care in Obstetrics. In M. Belfort, J. Phelan, G.

Saade, M. Foley. Sickle Cell Disease and Pregnancy. (in press) 5. S. A. Srour and Muzaffar H. Qazilbash. Chronic Myeloid Leukemias in: “The Bethesda

Handbook of Clinical OncologyEditors: Jame Abraham and James L. Gulley. 5th edition. 2017. In Press.

6. S. A. Srour and Muzaffar H. Qazilbash. Chronic Myeloid Leukemias in:“The Bethesda

Handbook of Clinical Oncology”. Editors: Jame Abraham and James L. Gulley. 1ST edition. 2017. In Press.

13

American Society of Clinical Oncology Session Chair, Prostate Cancer 2018 Annual Meeting American Society of Cancer Institutes Physician Clinical Leadership Initiative Steering Committee Member Baylor Principal Investigator for Southwest Oncology Group; Member GU Oncology Committee of the Southwest Oncology group; Member of SWOG Board of Governors; Co-Chair Planning Committee for BCM/MDACC Comprehensive Board Review in Hematology and Medical Oncology;

4. Mitsiades,N: Southwest Oncology Group; Member GU Oncology Committee

5. Musher, B: Southwest Oncology Group; Member GI Oncology Committee

6. Rivero, G: Southwest Oncology Group; Member Leukemia Committee

7. Sabichi, A: Southwest Oncology Group; Member Lung Cancer Committee

8. Sada, Y: Southwest Oncology Group; Member GI Oncology Committee

9. Smaglo, B: Southwest Oncology Group; Member GI Oncology Committee Sosa, R: American Society of Hematology

Member, Question writing committee for ASH SAP 10. Udden, M:

American Board of Internal Medicine Chair, Hematology Board

11. Yen, A: Southwest Oncology Group; Member GU Oncology Committee

E. Editorial Board Memberships and Editorial Positions Brenner, M: Editor and Chief Molecular Therapy Heslop, H: Editorial Board: Blood Journal, Hematology News, Cytotherapy Deputy Editor: Molecular Therapy, Associate Editor: Blood Mims, M: Associate Editor: Translational Research Mitsiades, N: Editorial Board: Endocrine Related Cancer, International Journal of Oncology, Journal of the Endocrine Society Musher, B: Clinical Gastroenterology and Hepatology reviewer (ad hoc); New England Journal of Medicine reviewer (ad hoc) Osborne, CK: Editorial Board: Breast Cancer Research, Cancer Research Rivero, G: Associate Editor: Blood Research and Disorders Journal Sabichi, A: Editorial Board, The Scientific World Journal; Editorial Board, New Journal of

14

Science

F. Grants 1. Arber Barth, C: Genetically Engineered Virus-Specific T Cells To Prevent And Treat

Relapse And Infection After Allogeneic Hematopoietic Stem Cell Transplantation Leukemia & Lymphoma Society 6490-16 (10/1/2015 - 9/30/2018)

2. Brenner, M Engineering T Cells To Ensure Specificity For Tumor Cells And Their Environment Cancer Prevention & Research Institute Of Texas (CPRIT) RP160345 (9/15/2016 - 2/28/2019)

3. Brenner, M: Amendment/NCE - To Extend Agreement- Followup For Lokon (Sample Analysis For The Clinical Trial) Lokon Pharma Ab (10/15/2017 - 10/14/2018)

4. Carrum, G: A Multi-Center, Randomized, Double-Blind, Placebo-Controlled Phase Iii Trial Of The Flt3 Inhibitor Gilteritinib Administered As Maintenance Therapy Following Allogeneic Transplant For Patients With Flt3-Itd Aml Bmt Ctn Protocol #1506/Astellas Astellas Pharma Global Development , Inc. Protocol Rider 1501 (Amend1) (12/7/2017 - 8/31/2018)

5. Chamness, G: NRG Oncology Biospecimen Bank National Institutes Of Health (NIH) U24-CA196067-04 (4/1/2015 - 3/31/2019)

6. Chamness, G: A Phase II Clinical Trial Platform Of Sensitization Utilizing Total Neoadjuvant Therapy (TNT) In Rectal Cancer (The "G1002 Project" National Surgical Adjuvant Breast And Bowel Project (NSABP) NRG-G1002 (11/1/2016 - 10/31/2018)

7. Chamness, G: NCE - NSABP B47 Sub Study NIH: National Institutes Of Health NONE-NSABP (NCE) (8/1/2017 - 12/31/2017)

8. Creighton, C: Mira / Core 2 - Integrated Analysis Of The Lung Cancer Microenvironment Cancer Prevention & Research Institute Of Texas (CPRIT) RP120713-C2 Year 6 (Year 1: 8/31/2017 - 8/31/2018)

9. Creighton, C: BC150251: A Novel Preclinical Model Of Dormant Metastatic ER+ Breast Cancer Department Of Defense W81XWH-16-1-0044 (2/1/2018 - 1/31/2019)

10. Creighton, C: Regulation Of Lung Cancer Metastasis By Zeb1 National Cancer Institute (NCI) R01-CA181184-04 (7/1/2014 - 6/30/2018)

11. Ellis, M: Alternate Trial: A Neoadjuvant Biomarker Approach For Estrogen Receptor Positive Breast Cancer Breast Cancer Research Foundation BCRF-16-102 (10/1/2014 - 9/30/2018) $11,544

12. Ellis, M: Investigation Of The Genomics And Biology Of Metastasis Using Patient-Derived-Xenografts (PDX) Breast Cancer Research Foundation ELFF-16-003 (9/1/2014 - 5/31/2018)

13. Ellis, M: 16-Month NCE BCRF PDX Founders Fund - Investigation Of The Genomics And Biology Of Metastasis Using Patient-Derived-Xenografts (PDX) Breast Cancer Research Foundation ELFF-16-003 - NCE (amend5 MSK) (6/1/2018 - 6/30/2019)

14. Ellis, M: BR003-A Randomized Phase III Trial Of Adjuvant Therapy Comparing Doxorubicin Plus Cyclophosphamide Followed By Weekly Paclitaxel With Or Without Carboplatin In Node-Positive Or High-Risk Node-Negative Triple-Negative Invasive Breast Cancer Breast Cancer Research Foundation BCRF-16-042 (10/1/2014 - 9/30/2018)

15. Ellis, M: Established Investigator Recruit - Accelerating Breast Cancer Translational Medicine Through Genomics And Proteomics Cancer Prevention & Research Institute Of Texas (CPRIT) RR140033 (6/1/2014 - 5/31/2019)

16. Ellis, M: Integrated Translational Genoproteomics Center At Washington University (Wu-18-361) National Institutes Of Health (NIH) U10-CA180860 (3/1/2014 - 2/28/2019)

15

17. Ellis, M: NRG Oncology Network Group Operations Center National Institutes Of Health (NIH) U10-CA180868-05 (3/1/2014 - 2/28/2019)

18. Ellis, M: Microscaled Proteogenomics For Cancer Clinical Trials (Cptac) National Institutes Of Health (NIH) U01-CA214125 -02 (Amend2 BI) (6/1/2017 - 5/31/2022)

19. Ellis, M: Somatic Mutation And Recurrence Risk For Early Stage Estrogen Receptor Positive Breast Cancer Susan G Komen Breast Cancer Foundation SAC170059 (YR2-WUSTL) (2/20/2017 - 2/19/2019)

20. Ellis, M: Direct Regulation Of Estrogen Receptor Transcriptional Activity By Nf1 United States Army Medical Research & Materiel Command ( Department Of Defense ) W81XWH-16-1-0539 (9/30/2016 - 9/29/2019)

22. Fuqua, S: Role Of Esr1 Mutations In Breast Cancer Progression Breast Cancer Research Foundation BCRF-16-056 (10/1/2014 - 9/30/2018)

23. Fuqua, S: Mira/Project 2: Characterization Of Nuclear Receptor And Co-Regulator Expression And Function In Breast Cancers Cancer Prevention & Research Institute Of Texas (CPRIT) RP120732-P2 Attach F2 (8/31/2012 - 8/30/2018)

24. Fuqua, S: Year 4 NCE: Effects Of Hormonal Therapy On Subclonal Evolution Of Breast Tumors With Esr1 Mutations Cancer Prevention & Research Institute Of Texas (CPRIT) RP150440 (3/1/2015 - 8/31/2018)

25. Fuqua, S: Integration Of Predictive Biomarkers Of Hormone Resistance In Breast Cancer National Cancer Institute (NCI) R01-CA072038-19 (9/1/1996 - 8/31/2019)

26. Fuqua, S: Mechanisms Of Ar-Er Collaboration In Hormone Resistance And Metastasis Of Breast Cancer National Institutes Of Health (NIH) R01-CA207270-02 (3/1/2017 - 2/28/2022)

27. Haricharan, S: BC170276 Mismatch Repair Loss Renders Er+/Her2- Breast Cancer Susceptible To Her2/3 Inhibition United States Army Medical Research & Materiel Command ( Department Of Defense) W81XWH-18-1-0034 (3/1/2018 - 2/28/2019)

28. He, B: Role Of Gata2 In Prostate Cancer Development American Cancer Society RSG-13-061-01 (1/1/2015 - 12/31/2018)

29. Heslop, H: Enhancing T Cell Therapy of Cancer National Institutes Of Health (NIH) 5P01CA094237 (2/1/16-1/31/19)

30. Heslop, H. Cancer Cell and Gene Therapy Program (CCSG) National Institutes Of Health (NIH) 5P30CA125123 (7/1/2007-6/30/19)

31. Heslop, H: Translational Research In Lymphoma (SPORE) National Institutes Of Health (NIH) P50-CA126752 (4/1/2007-8/31/2022)

32. Heslop, H: Training in Cell and Gene Therapy National Institutes of Health (NIH) 5T32HL092332 (7/1/2003-7/31/2019)

33. Hoyos, V: Recruitment Of First-Time, Tenure Track Faculty Member–Dr. Valentina Hoyos Velez (RFT) Cancer Prevention & Research Institute Of Texas (CPRIT) RR170024 (8/31/2017 - 8/30/2022)

34. Jiralerspong, S: NCE 2- Metformin For The Treatment Of Breast Ductal Carcinoma In Situ (DCIS) Susan G Komen Breast Cancer Foundation CCR13263802 (8/27/2017 - 8/26/2018)

35. Kavuri, M: BC170466: Targeting Ddr1 Aberrations In Metastatic Er+ Breast Cancer Department Of Defense Congressionally Directed Medical Research Programs W81XWH-18-1-0040 (2/15/2018 - 2/14/2019)

36. Kavuri, M: Kinome Analysis To Rationalize Targeting HER2 And DDR1 Breast Cancer Mutations Susan G Komen Breast Cancer Foundation CCR16380599 (9/15/2016 - 9/14/2019)

37. Kavuri, M: BC170276P1 Mismatch Repair Loss Renders Er+/Her2- Breast Cancer Susceptible To Her2/3 Inhibition United States Army Medical Research & Materiel

16

Command ( Department Of Defense ) W81XWH-18-1-0035 (3/1/2018 - 2/28/2021)

38. Lin, W: NCE: BC133678 Targeting A Convergent Point Of Multiple Oncogenic Pathways In Breast Cancer, A New Paradigm For Targeted Therapy Department Of Defense Congressionally Directed Medical Research Programs W81XWH-14-1-0339 (9/30/2017 - 9/29/2018)

39. Lin, W: The ATM/E2F1 Pathway In Dna Damage And Growth Control National Institutes Of Health (NIH) R01-CA100857-14 (3/1/2003 - 2/28/2020

40. Lin, W: MPI-Novel Therapeutics For Targeting Checkpoint Dysfunction In Cancer National Institutes Of Health (NIH) R01-CA203824-02 (12/1/2016 - 11/30/2021)

41. Lin, W: New Mechanisms Of Breast Cancer Metastasis And Loss Of Estrogen Receptor Driven By 14-3-3 (NIH): National Institutes Of Health R21-CA198041-02 (6/1/2016 - 5/31/2019)

42.. Lin, W: BCM Oncology Scholars Training Program The National Institutes Of Health T32-CA174647-04 (8/1/2014 - 7/31/2019)

43. Lulla, P: T Cell Therapy For AML American Society For Blood & Marrow TR (7/1/2016 - 6/30/2019)

44. Lulla, P: Safety And Efficacy Of Adoptively Transferred Multitaa Specific T Cells To Patients With Multiple Myeloma American Society Of Hematology (7/1/2017 - 6/30/20120)

45. Lulla, P: Adoptively Transferred Multitaa-Specific T Cells As Treatment Or Prevention Of Aml Relapse Post-Allogeneic Stem Cell Transplant Leukemia Texas, Inc. (7/1/2016 - 6/30/2018)

46. Mamonkin, M: Increasing Safety Of Cd5 Car For The Treatment Of T Cell Malignancies American Society Of Hematology (7/1/2016 - 6/30/2019)

47. Mitsiades, N: Ubiquitination-Based Control Of Transcriptional Activity In Prostate Cancer American Cancer Society RSG-14-218-01-TBG (1/1/2015 - 12/31/2018)

48. Mitsiades, N: PC160445: A First-In-Field Approach To Target A Previously Undruggable Oncogene Family In Prostate Cancer Department Of Defense Congressionally Directed Medical Research Programs W81XWH-17-1-0298 (7/1/2017 - 6/30/2020)

49. Mitsiades, N: Developing Spop Inhibitors Diana Helis Henry Medical Research Foundation Cancer Program H-2017 (4/1/2017 - 3/31/2019)

50. Mitsiades, N: Regulation Of Uveal Melanoma Cell Fate By Mitf Via The PKC Pathway National Cancer Institute (NCI) R01-CA193321-03 (8/1/2015 - 7/31/2020)

51. Mitsiades, N: A Novel Therapeutic Target For Prostate Cancer Sidney Kimmel Foundation For Cancer R SKF-15-053 (7/1/2015 - 6/30/2018)

52. Nangia, J: Breast Cancer Research And Education Program Astrazeneca (9/7/2017 - 9/6/2018)

53. Nangia, J: Nanostring Educational Grant Nanostring Technologies NanoString (8/1/2017 - 7/31/2018)

54. Nangia, J: Educational Retreat Pfizer, Inc (9/1/2016 - 8/31/2018) 55. Nangia, J: 2018-2019: Facilitating Breast Cancer Prevention And Treatment In

Underserved And Minority Women Susan G Komen - Houston Affiliate CGA-2018-TX105-BAYL46-00030 (4/1/2018 - 3/31/2019)

56. Osborne, C K: Baylor College Of Medicine Cancer Center National Cancer Institute (NCI) P30-CA125123-11 (7/1/2007 - 6/30/2020)

17

57. Osborne, C KP30 Administrative Supplement For P30 Cancer Center Support Grants To Support Research In Canine Immunotherapy Via Collaboration Of Nci-Designated Cancer Centers And Veterinary Medical Colleges (Identifying Neo-Epitopes For Cd8+ T Cells In Dog Tumors) National Cancer Institute (NCI) P30-CA125123-10S4 (7/1/2017 - 12/31/2018)

58. Osborne, C K: RFA: NCI Moonshot Initiative: Administrative Supplements For The P30 Cancer Center Support Grant To Develop Tobacco Cessation Treatment Capacity And Infrastructure For Cancer Patients National Cancer Institute (Nci) P30-CA125123 (7/1/2017 - 6/30/2018)

59. Osborne, C K: 11S2 Underrepresented High School And Undergraduate Student Research Experiences (Cure) National Cancer Institute (NCI) P30-CA125123-11S2 (7/1/2017 - 6/30/2018)

60. Osborne, C K: 11S1 Administrative Supplement To Strengthen NCI-Supported Community Outreach Capacity Through Community Health Educators (CHES) Of The National Outreach Network (NON) National Cancer Institute (NCI) P30-CA125123-11S1 (7/1/2017 - 6/30/2018)

61. Osborne, C K: To Fund Year 11 Administrative Supplement Not Affiliated With The Experimental Therapeutic Clinical Trials Network (Etctn) To Support Participation In The Etctn Prior Year: 10 ( Brain 23664-S37) National Cancer Institute (NCI) P30-CA125123 (7/1/2017 - 6/30/2018)

62. Osborne, C K: 11S3 : Improving Diagnostic Accuracy And Supportive Care For Children With Burkitt Lymphoma: Laying A Foundation For Treatment Trials In Sub-Sahara Africa National Cancer Institute (NCI) P50-CA125123 (7/1/2017 - 6/30/2018)

63. Osborne, C K: Translational Research In Breast Cancer (SPORE) National Institutes Of Health (NIH) P50-CA186784-04 (9/1/2014 - 8/31/2019)

64. Osborne, C K: Amendment 2 To The Ventana Collaborative Research Agreement Ventana Medical Systems, Inc (1/24/2018 - 6/30/2018)

65. Ramos, C: Amendment: HPV 16/18 E6/E7-Specific T Cells For Treatment Of HPV-Associated Cancers Tessa Therapeutics Pte. Ltd. (5/1/2018 - 4/30/2019)

66. Rimawi, M: Pink For Life- Expanding And Improving Breast Cancer Care And Prevention In Minority And Economically Disadvantaged Women Avon Foundation 05-2017-002 (7/1/2017 - 6/30/2018)

67. Rimawi, M: NCE TBCRC 2017: Translational Breast Cancer Research Consortium Infrastructure Support Task Order: BCRF Original Po 2000010764 Breast Cancer Research Foundation (7/1/2017 - 6/30/2018)

68. Rimawi, M: BC161327: A New Paradigm For De-Escalation Of Treatment In Her2 Positive Breast Cancer: Revolutionizing Care With More Effective And Less Toxic Therapy. Department Of Defense Congressionally Directed Medical Research Programs W81XWH-17-1-0579 (9/15/2017 - 9/14/2020)

69. Rimawi, M: Biological Samples For: A Phase II Randomized Study Evaluating The Biological And Clinical Effects Of The Combination Of Palbociclib With Letrozole As Neoadjuvant Therapy In Women With Estrogen Receptor-Positive Primary Breast Cancer” (The “Fb-11 Study) Pfizer, Inc Service Agreement (10/20/2017 - 10/19/2019)

70. Rimawi, M: TBCRC 2017: Translational Breast Cancer Research Consortium Infrastructure Support Task Order: Susan G Komen Breast Cancer Foundation (7/1/2017 - 6/30/2018)

71 Schiff, R: 2017-2018: Mechanisms Of Resistance To HER2 And ER-Targeted Therapies And Novel Therapeutic Strategies Breast Cancer Research Foundation BCRF-17-143 (10/1/2017 - 9/30/2018)

18

72. Schiff, R: Pre-Clinical Investigation Of Brd4 Inhibitors In Hormone-Insensitive Er+ Breast Cancer Gilead Sciences, Inc. (12/15/2017 - 2/17/2019)

73. Schiff, R: NIK As Attractive Drug Target For Intractable Breast Cancer” (5R01CA18136) National Institutes Of Health (NIH) R01-CA181368-04 (9/1/2014 - 8/31/2018)

74. Schiff, R: Evaluate The Therapeutic Efficacy Of Neratinib In Combination With Trastuzumab For HER2-Positive Breast Cancer Puma Biotechnology Inc SRA (1/1/2018 - 12/31/2019)

75. Schiff, R: BC133693P1: Targeting Gpr110 In Her2-Overexpressing Breast Cancer United States Army Medical Research & Materiel Command ( Department Of Defense ) W81XWH-14-1-0341 (9/30/2014 - 9/29/2018)

76. Schiff, R: Harvey Amendment BC133693P1: Targeting GPR110 In HER2-Overexpressing Breast Cancer United States Army Medical Research & Materiel Command (Department Of Defense ) W81XWH-14-1-0431 (4/26/2014 - 9/30/2018)

77. Schiff, R: BC161327P1 : A New Paradigm For De-Escalation Of Treatment In HER2 Positive Breast Cancer: Revolutionizing Care With More Effective And Less Toxic Therapy. United States Army Medical Research & Materiel Command ( Department Of Defense ) W81XWH-17-1-0580 (9/15/2017 - 9/14/2020) $692,420

78. Sosa, I R: Resveratrol In Metabolic Syndrome: Effect On Platelet Hyper-Reactivity And Hdl Lipid Peroxidation American Heart Association Inc 13FTF174000111 (7/1/2014 - 6/30/2018)

79. Suzuki, M: Combining Ad Gene Therapy With Car Ad-Specific T-Cell Therapy For HNSCC Concern Foundation (7/1/2016 - 6/30/2018)

80. Suzuki, M: Amendment - Combinatorial Treatment With Armed Oncolytic Ad Gene Therapy And Car T-Cell Therapy For Squamous Cell Carcinoma Of The Head And Neck (HNSCC) Tessa Therapeutics Pte. Ltd. SRA Amendment 1 (1/1/2018 - 12/31/2018) $100,000

81. Vera Valdes, J:: Engineered T Cell Therapy For Advanced Prostate Cancer American Cancer Society MRSG-14-19701-LIB (1/1/2015 - 12/31/2018)

82. Watanabe, N: Cook Regentec LLS SRA Cook Regentec Testing Agreement (9/21/2017 - 9/20/2018)

G. Cash Awards 1. Carrum, G: Astellas Pharma Global Development , Inc. A Randomized, Double-Blind,

Placebo-Controlled Phase 3 Trial To Evaluate The Protective Efficacy And Safety Of A Therapeutic Vaccine, Asp0113, In Cytomegalovirus (Cmv)-Seropositive Recipients Undergoing Allogeneic Hematopoietic Cell Transplant (HCT)

2. Carrum, G: National Institutes Of Health (NIH) U10HL069294 Prospective Multi-Center Cohort For The Evaluation Of Biomarkers Predicting Risk Of Complications And Mortality Following Allogeneic HCT, BMT CTN 1202

3. Carrum, G: NIH: National Institutes Of Health U10CA180888 **Swog Purchase Service Agreement: Subaccount For Participation In Nci Nctn Clinical Trials** CTSU - H-39725 BMT CTN 1201 A051301 Alliance DLBC - A Randomized Double-Blind Phase Iii Study Of Ibrutinib During And Following Autologous Stem Cell Transplantation Versus Placebo In Patients With Relapsed Or Refractory Diffuse Large B-Cell Lymphoma Of The Activated B-Cell Subtype

4. Chamness, G: NIH: National Institutes Of Health NSABP B47 Sub Study 5. Heslop, H: Cell Medica, Ltd Citadel-A Phase 2 Open Label Study To Investigate The

Efficacy Of Autologous Ebv-Specific T-Cells For The Treatment Of Patients With

19

Aggressive Extranodal Nk/T Cell Lymphoma (ENKTCL), CM-2013-01

6. Heslop, H: Cell Medica, Ltd Prevale- Phase I Study Combining Nivolumab With Epstein Barr Virus Specific T Cells (Eb-Vsts) In Relapsed/Refractory Ebv Positive Lymphoma Patients

7. Kamble, R: National Institutes Of Health (NIH) 2U10HL069294 A Multi-Center Biologic Assignment Trial Comparing Reduced Intensity Allogeneic Hematopoietic Cell Transplant To Hypomethylating Therapy Or Best Supportive Care In Patients Aged 50-75 With Intermediate-2 And High Risk Myelodysplastic Syndrome, BMT CTN 1102

8. Lulla, P: National Institutes Of Health (NIH) U01HL128566-01 Year 3 Amendment - BMT CTN 1503: Hematopoietic Stem Cell Transplantation For Young Adults With Sickle Cell Disease

9. Lulla, P: Tessa Therapeutics Pte. Ltd. A Multicentre, Randomized, Open-Label, Phase Iii Clinical Trial Of Gemcitabine And Carboplatin Followed By Epstein-Barr Virus-Specific Autologous Cytotoxic T Lymphocytes Versus Gemcitabine And Carboplatin As First Line Treatment For Advanced Nasopharyngeal Carcinoma Patients

10. Mims, M: Aveo Pharmaceuticals A Phase 3, Randomized, Controlled, Multi-Center, Open-Label Study To Compare Tivozanib Hydrochloride To Sorafenib In Subjects With Refractory Advanced Renal Cell Carcinoma

11. Mims, M: Bristol-Myers Squibb 1 Ca204006: A Phase 3, Randomized, Open Label Trial Of Lenalidomide/Dexamethasone With Or Without Elotuzumab In Subjects With Previously Untreated Multiple Myeloma

12. Mims, M: Celgene Corporation Cc-5013-Nhl-008: A Phase 3B Randomized Study Of Lenalidomide (CC-5013) Plus Rituximab Maintenance Therapy Followed By Lenalidomide Single-Agent Maintenance Versus Rituximab Maintenance In Subjects With Relapsed/Refractory Follicular, Marginal Zone Or Mantle Cell Lymphoma

13. Mims, M: Imclone Systems Incorporated Cp02-0452: Randomized Phase Iii Study Of Docetaxel Or Pemetrexed With Or Without Cetuximab In Patients With Recurrent Or Progressive Non-Small Cell Lung Cancer After Platinum-Based Therapy

14. Mims, M: Novartis Pharmaceuticals Corp 1 Rad001N2301: A Randomized, Double-Blind, Placebo-Controlled, Multicenter Phase Iii Study Of Rad001 Adjuvant Therapy In Poor Risk Patients With Diffuse Large B-Cell Lymphoma (DLBCL) Of Rad001 Versus Matching Placebo After Patients Have Achieved Complete Response With First-Line Rituximab-Chemotherapy

15. Mims, M: Prostate Cancer Clinical Trials Consortium, Llc Prostate Cancer Outcomes: An International Registry To Improve outcomes In Men With Advanced Prostate Cancer (Ironman)

16. Musher, B: Aduro Biotech, Inc. A Phase 2, Open-Label Evaluation Of Crs-207 And Pembrolizumab In Adults With Recurrent Or Metastatic Gastric, Gastroesophageal Junction, Or Esophageal Adenocarcinomas

17. Musher, B: Boston Biomedical, Inc Canstem111P: A Phase III Study Of Bbi-608 Plus Nab-Paclitaxel With Gemcitabine In Adult Patients With Metastatic Pancreatic Adenocarcinoma.

18. Musher, B: Celgene Corporation Abi-007-Panc-003 A Phase 3, Multicenter, Open-Label,Randomized Study Of Nab®-Paclitaxel Plus Gemcitabine Versus Gemcitabine Alone Asadjuvant Therapy In Subjects With Surgically Resected Pancreatic Adenocarcinoma

19. Musher, B: Eli Lilly And Company A Randomized, Double-Blind, Placebo-Controlled Phase 3 Study Of Capecitabine And Cisplatin With Or Without Ramucirumab As First-Line Therapy In Patients With Metastatic Gastric Or Gastroesophageal Junction Adenocarcinoma (Rainfall)

20

20. Musher, B: Halozyme Therapeutics A Phase 3, Randomized, Double-Blind, Placebo-Controlled, Multicenter Study Of Pegylated Recombinant Human Hyaluronidase (Pegph20) In Combination With Nab-Paclitaxel Plus Gemcitabine Compared With Placebo Plus Nab-Paclitaxel And Gemcitabine In Subjects With Hyaluronan-High Stage Iv Previously Untreated Pancreatic Ductal Adenocarcinoma

21. Musher, B: Lokon Pharma Ab Phase I/Iia Trial Evaluating Safety Of Load703 An Armed Oncolytic Adenovirus For Pancreatic Cancer

22. Musher, B: Merck Sharpe & Dohme Corp. A Phase III Study Of Pembrolizumab (Mk-3475) Vs. Chemotherapy In Microsatellite Instability-High (Msi-H) Or Mismatch Repair Deficient (Dmmr) Stage Iv Colorectal Carcinoma (Keynote-177)

23. Musher, B: Newlink Genetics Corporation 1 Nlg-0505: A Phase III Study Of Folfirinox With Or Without Hyperacute-Pancreas (Algenpantucel-L) Immunotherapy In Subjects With Borderline Resectable Or Locally Advanced Unresectable Pancreatic Cancer

24. Nangia, J: Calithera Biosciences H-41704: A Multicenter Phase 2 Study Of The Glutaminase Inhibitor Cb-839 In Combination With Paclitaxel In Patients With Advanced Triple Negative Breast Cancer (Tnbc) Including Patients Of African Ancestry And Non-African Ancestry

25. Nangia, J: Celldex Therapeutics, Inc. A Randomized Multicenter Pivotal Study Of Cdx-011 (Cr011-Vcmmae) In Patients With Metastatic, Gpnmb Over-Expressing, Triple-Negative Breast Cancer

26. Nangia, J: Paxman Coolers Limited Scalp Cooling For Alopecia Prevention (Scalp) 27. Nangia, J: Tesaro, Inc. H-42264: 3000-01-005 An Open-Label, Single-Arm Pilot Study

Evaluating The Antitumor Activity And Safety Of Niraparib As Neoadjuvant Treatment In Localized, Her2- Negative, Brca-Mutant Breast Cancer Patients

28. Ramos, C: Viracyte LLC A Phase I Study Using Most Closely Hla-Matched Adenovirus-Specific T-Lymphocytes For The Treatment Of Adenovirus Infections Post Allogeneic Stem Cell Transplant (Viralym-A)

29. Rimawi, M: Abbvie Inc H-42427: An Open Label Study Of Sc-005 In Subjects With Triple Negative Breast Cancer (Tnbc)

30. Rimawi, M: Amgen, Inc. "A Randomized, Double-Blind, Placebo-Controlled, Multi-Center Phase 3 Study Of Denosumab As Adjuvant Treatment For Women With Early-Stage Breast Cancer At High Risk Of Recurrence (D-Care).

31. Rimawi, M: Breast Cancer Research Foundation Tbcrc 026 Amendment 1: A Phase 2 Clinical Trial Assessing The Correlation Of Early Changes In Standardized Uptake Value (Suv) On Positron Emission Tomography (Pet) With Pathological Complete Response (Pcr) To Pertuzumab And Trastuzumab In Patients With Primary Operable Her2-Positive Breast Cancer

32. Rimawi, M: Cascadian Therapeutics, Inc. 1 H-40306: Phase 2 Randomized, Double-Blinded, Controlled Study Of Ont-380 Vs. Placebo In Combination With Capecitabine And Ont-380-206: Trastuzumab In Patients With Pretreated Unresectable Locally Advanced Or Metastatic Her2+ Breast Carcinoma

33. Rimawi, M: Dana Farber Cancer Institute Tbcrc030: A Randomized Phase II Study Of Preoperative Cisplatin Versus Paclitaxel In Patients With Triple Negative Breast Cancer Without Germline Brca Mutations: Evaluating The Homologous Recombination Deficiency (Hrd) Biomarker

34. Rimawi, M: Galena Biopharma, Inc. Present: Prevention Of Recurrence In Early-Stage, Node-Positive Breast Cancer With Low To Intermediate Her2 Expression With Neuvax™ Treatment

35. Rimawi, M: Genentech Foundation For Growth & Dev A Phase II, Double-Blind, Placebo-Controlled, Randomized Study Of Gdc-0941 Or Gdc-0980 With Fulvestrant Versus Fulvestrant In Advanced Or Metastatic Breast Cancer In Patients Resistant To

21

Aromatase Inhibitor Therapy 36. Rimawi, M: Genentech, Inc. Pertain / Protocol Number Mo27775 / Ro43-68451

Pertuzumab 37. Rimawi, M: Gilead Sciences, Inc. H-39960: Gsus3501937 A Phase 1B Study

Followed By An Open Label, Parallel, Randomized Phase 2 Study Evaluating The Safety, Tolerability And Efficacy Of Gs-5829 In Combination With Exemestane Or Fulvestrant Comparing With Exemestane Or Fulvestrant Alone In Subjects With Advanced Estrogen Receptor Positive Her2- Breast Cancer

38. Rimawi, M: Glaxo/Smithkline A Phase II Trial Of Lapatinib And Trastuzumab With Or Without Endocrine Therapy In Locally Advanced Her2 Overexpressing Breast Cancer Patients

39. Rimawi, M: Glaxo/Smithkline Neoadjuvant Study Of Extended Lapatinib And Trastuzumab With Or Without Endocrine Therapy In Locally Advanced Her2-Overexpressing Breast Cancer Patients

40. Rimawi, M: Novartis Pharmaceuticals Corp “A Randomized Phase III, Double-Blind, Placebo-Controlled, Multicenter Trial Of Daily Everolimus In Combination With Trastuzumab And Vinorelbine In Pretreated Women With Her2/Neu Over-Expressing Locally Advanced Or Metastatic Breast Cancer.”

41. Rimawi, M: Novartis Pharmaceuticals Corp H 36350: Lee011: A Phase III Randomized, Double-Blind, Placebo-Controlled Study Of Lee011 Or Placebo In Combination With Tamoxifen And Goserelin Or A Non-Steroidal Aromatase Inhibitor (Nsai) / Clee011E2301 (Monaleesa-7) And Goserelin For The Treatment Of Premenopausal Women With Hormone Receptor Positive, Her2-Negative, Advanced Breast Cancer

42. Rimawi, M: Pfizer, Inc Crizotinib And Sunitinib_ A Rationally Combined Targeted Therapy Strategy For Metastatic Triple Negative Breast Cancer

43. Rimawi, M: Pfizer, Inc Nsabp Fb-11: A Phase II Randomized Study Evaluating The Biological And Clinical Effects Of The Combination Of Palbociclib With Letrozole As Neoadjuvant Therapy In Post-Menopausal Women With Estrogen-Receptor Positive Primary Breast Cancer

44. Rimawi, M: Pfizer, Inc H-39113 Nsabp Protocol B-57-I: Pallas: Palbociclib Collaborative Adjuvant Study:A Randomized Phase Iii Trial Of Palbociclib With Standard Adjuvant Endocrine Therapy Versus Standard Adjuvant Endocrine Therapy Alone For Hormone Receptor Positive (Hr+) / Human Epidermal Growth Factor Receptor 2 (Her2)-Negative Early Breast Cancer

45. Rimawi, M: Synthon Biopharmaceuticals, B.V. H-41823: A Multi-Centre, Open-Label, Randomized Clinical Trial Comparing The Efficacy And Safety Of The Antibody-Drug Conjugate Syd985 To Physician'S Choice In Patients With Her2-Positive Unresectable Locally Advanced Or Metastatic Breast Cancer

46. Sada, Y: Merck & Co, Inc. Keynote-224: A Phase II Study Of Pembrolizumab (Mk-3475) As Monotherapy In Subjects With Previously Systemically Treated Advanced Hepatocellular Carcinoma

47. Smaglo, B: Mitra Biotech A Prospective, Multicenter, Observational Study Examining The Clinical Utility Of Canscripttm In Routine Clinical Practice

48. Zhang, J: Advaxis Window-Of Opportunity Trial Of Neoadjuvant Adxs11-001 Vaccination Prior To Transoral Resection Of Hpv-Positive Oropharyngeal Squamous Cell Carcinoma

49. Zhang, J: Astrazeneca A Phase III, Randomized, Multicenter, Open-Label, Comparative Study To Determine The Efficacy Of Durvalumab Or Durvalumab And Tremelimumab In Combination With Platinum-Based Chemotherapy For The First-Line Treatment In Patients With Extensive Disease (Stage Iv) Small-Cell Lung Cancer (Sclc)

22

50. Zhang, J: Regeneron Pharmaceuticals, Inc 1 A First-In-Human Study Of Repeat Dosing With Regn2810, A Monoclonal, Fully Human Antibody To Programmed Death – 1 (Pd-1), As Single Therapy And In Combination With Other Anti-Cancer Therapies, In Patients With Advanced Malignancies

Immunology, Allergy & Rheumatology


Section of Immunology, Allergy & Rheumatology Department of Medicine, Baylor College of Medicine (1 July 2017–30 June 2018) A. Publications Journal articles Sandeep Agarwal

1. Wu M, Baron M, Pedroza C, Salazar G, Ying J, Charles J, Agarwal SK, Hudson M, Zhou X, Reveille JD, Fritzler M, Mayes M, Assassi S. CCL-2 in circulation predicts long-term progression of interstitial lung disease in early systemic sclerosis: data from two independent cohorts. Arthritis and Rheumatology. 69(9):1871-78, 2017

2. Pedroza M, To S, Assassi S, Wu M, Tweardy D, Agarwal SK. Role of STAT3 in skin fibrosis and

TGF-beta signaling. Rheumatology. Epub 2017.

3. Pedroza M, Welschhans RL, Agarwal SK. Targeting of cadherin-11 decreases dermal fibrosis in the tight skin-1 mouse model. PlosOne. 12(11): e0187109, 2017.

4. Mah AY, Rashidi A, Keppel MP, Saucier N, Moore EK, Alinger JB, Tripathy SK, Agarwal SK, Jeng

EK, Wong HC, Miller JS, Fehniger TA, Mace EM, French AR, Cooper MA. Glycolytic requirement for NK cell cytotoxicity and cytomegalovirus control. Journal of Clinical Investigation Insight. 2(23), pii 95128, 2017.

5. Niravath P, Chen B, Gelmon K, Kalari K, Osborne K, Shepherd L, Ingle J, Chapman JA, Pritchard K, Bartlett J, Hilsenbeck S,Goss P,Agarwal SK, Welschhans R, Bongartz T, Rimawi M. Vitamin D levels, vitamin D receptor polymorphisms, and inflammatory cytokines in aromatase inhibitor-induced arthralgias: An analysis of CCTG MA.27. Submitted to Clinical Breast Cancer. 19(1):78-87, 2018.

6. Karmouty-Quintana H, Molina JG, Philip K, Bellocchi C, Gudenkauf B, Wu M, Chen NY, Collum SD,

Ko J, Agarwal SK, Assassi S, Zhong H, Blackburn, MR, Weng, T. The anti-fibrotic effect of adenosine A2B receptor antagonism in a mouse model of dermal fibrosis. Arthritis and Rheumatology, Epub May 2018.

Joan Appleyard N/a David Corry

1. Hong MJ, Gu BH, Madison, MC, Landers C, Tung HY, Kim M, Yuan X, You R, Machado AA, Gilbert BE, Soroosh P, Elloso M, Song L, Chen M, Corry DB, Diehl G, Kheradmand F. Protective Role

of gd T cells in Cigarette Smoke and Influenza Infection. Mucosal Immunol 2017; 11(3):894-908 PMCID: PMC5930147

2. Liang D, Tian L, You R, Halpert MM, Konduri V, Baig Y C, Paust S, Kim D, Kim S, Jia F, Huang S, Zhang X, Kheradmand F, Corry DB, Gilbert BE, Levitt JM, Decker WK. AIMp1 Potentiates TH1 Polarization and Is Critical for Effective Antitumor and Antiviral Immunity. Front Immunol 2017; 8:1801 PMCID: PMC5775236

3. Li E, Tsai C-L, Maskatia ZK, Kakkar E, Porter P, Rossen RD, Perusich S, Knight JM, Kheradmand F,

Corry DB. Benefits of antifungal therapy in asthma patients with airway mycosis: a retrospective cohort analysis. Immun Inflamm Dis 2018; 6:264-275 PMCID: PMC5946149

4. You R, DeMayo F, Liu J, Cho S-N, Burt B, Creighton C, Casal R, Lazarus D, Lu W, Tung H-Y, Yuan X,

Hill-McAlester A, Kim M, Perusich S, Cornwell L, Rosen D, Song L-Z, Paust S, Diehl G, Corry DB, Kheradmand F. IL17A Regulates Tumor Latency and Metastasis in Lung Adeno and Squamous SQ.2b and AD.1 Cancer. Cancer Immun Res 2018; 6:645-657.

5. Knight JM, Mandal P, Morlacchi P, Mak G, Li E, Madison M, Landers C, Saxton B, Felix E, Gilbert

B, Sederstrom J, Varadhachary A, Singh MM, Chatterjee D, Corry DB, McMurray JS. Small Molecule Targeting of the STAT5/6 Src Homology 2 (SH2) Domains to Inhibit Allergic Airway Disease. J Biol Chem 2018. doi: 10.1074/jbc.RA117.000567

6. Cho M., Lee JE, Lim H, Shin HW, Khalmuratova R, Choi G, Kim HS, Choi WS, Park YJ, Shim I, Kim

BS, Kang CY, Kim JO, Tanaka S, Kubo M, Tung HY, Landers CT, Corry DB, Kheradmand F, Chung Y. Fibrinogen cleavage products and Toll-like receptor 4 promote the generation of programmed cell death 1 ligand 2-positive dendritic cells in allergic asthma. J Allergy Clin Immunol 2018. 142: 530-541.e6

7. Tung H-Y, Li E, Landers C, Nguyen A, Kheradmand F, Knight JM, Corry DB. Advances and Evolving

Concepts in Allergic Asthma. Sem Respir Crit Care Med 2018. 39:64-81.

8. Gu B-H, Madison M, Corry DB, Kheradmand, F. Matrix Remodeling in Chronic Lung Diseases. Matrix Biol 2018 pii: S0945-053X(17)30372-4.

9. Knight JM, Li E, Tung HY, Landers C, Wheeler J, Kheradmand F., Corry, DB. A Fungal Protease

Model to Interrogate Allergic Lung Immunity. Methods Mol Biol 2018. 1799: 1-9.

10. Li E, Tsai CL, Maskatia ZK, Kakkar E, Porter P, Rossen RD, Perusich S, Knight JM, Kheradmand F, Corry DB. Benefits of antifungal therapy in asthma patients with airway mycosis: A retrospective cohort analysis. Immun Inflamm Dis. 2018 Jun;6(2):264-275. Epub 2018 Mar 25. PMID: 29575717

Sana Hasan N/a Onome Ifoeze (Whiteru) N/a

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5775236/




Grace Lo

1. Lo GH, Strayhorn MT, Driban JB, Price LL, Eaton CB, McAlindon TE. Subjective Crepitus as a Risk Factor for Incident Symptomatic Knee Osteoarthritis: Data from the Osteoarthritis Initiative. Arthritis Care and Research (Hoboken). 2018 Jan;70(1):53-60. PMID: 28470832. PMCID: PMC5671376.

2. Lo GH, Driban JB, Price LL, Eaton CB, McAlindon TE. Systolic and Pulse Pressure Associate with

Incident Knee Osteoarthritis: Data from the Osteoarthritis Initiative. Clinical Rheumatology. 2017 Sep;36(9):2121-2128 PMID: 28573369. PMCID: PMC5709188.

3. Davis JE, Price LL, Lo GH, Eaton CB, McAlindon TE, Lu B, Barbe MF, Driban JB. A single recent

injury is a potent risk factor for the development of accelerated knee osteoarthritis: data from the osteoarthritis initiative. Rheumatol Int. 2017 Oct;37(10):1759-1764. PMID: 28831543. PMCID: PMC5693623.

4. Lo GH, Merchant M, Driban JB, Duryea J, Price LL, Eaton CB, McAlindon TE. Knee Alignment is

Quantitatively Related to Periarticular Bone Morphometry and Density, Especially in those with Osteoarthritis. Arthritis Rheumatol. 2018 Feb;70(2):212-221. PMID: 28940779.

5. Malaty HM, Lo GH, Hou JK. Characterization and prevalence of spondyloarthritis and peripheral

arthritis among patients with inflammatory bowel disease. 2017 Sep 27;10:259-263. PMID: 29026327 PMCID: PMC5627736.

6. Stout AC, Barbe MF, Eaton CB, Amin M, Al-Eid F, Price LL, Lu B, Lo GH, Zhang M, Pang J,

McAlindon TE, Driban JB. Inflammation and glucose homeostasis are associated with specific structural features among adults without knee osteoarthritis: a cross-sectional study from the osteoarthritis initiative. BMC Musculoskelet Disord. 2018 Jan 5;19(1):1921-6. PMID: 29304778 PMCID: PMC5755424.

7. Lo GH, Schneider E, Driban JB, Price LL, Hunter DJ, Eaton CB, Hochberg MC, Jackson RD, Kwoh

CK, Nevitt M, Lynch JA, McAlindon TE. Periarticular Bone Predicts Knee Osteoarthritis Progression Data from the Osteoarthritis Initiative. Seminars of Arthritis and Rheumatism. 2018 Jan 31. E-pub ahead of print.

8. Driban JB, McAlindon TE, Amin M, Price LL, Eaton CB, Davis JE, Lu B, Lo GH, Duryea J, Barbe MF.

Risk Factors can Classify Individuals who Develop Accelerated Knee Osteoarthritis: Data from the Osteoarthritis Initiative. Journal of Orthopedic Research. 2018 Mar;36(3):876-880. PMID: 28776751

9. Davis JE, Harkey MS, Ward RJ, Mackay JW, Lu B, Price LL, Eaton CB, Barbe MF, Lo GH, McAlindon

TE, Driban JB. Characterizing the distinct structural changes associated with self-reported knee injury among individuals with incident knee osteoarthritis: Data from the osteoarthritis initiative. Clinical Anatomy. 2018 Apr;31(3):330-334. PMID: 29380495

10. Davis JE, Liu SH, Lapane K, Harkey MS, Price LL, Lu B, Lo GH, Eaton CB, Barbe MF, McAlindon TE, Driban JB. Adults with incident accelerated knee osteoarthritis are more likely to receive a knee replacement: data from the Osteoarthritis Initiative. Clinical Rheumatology. 2018 Apr;37(4):1115-1118. PMID: 29423719

11. MacKay JW, Kapoor G, Driban JB, Lo GH, McAlindon TE, Toms AP, McCaskie AW, Gilbert FJ.

Association of subchondral bone texture on magnetic resonance imaging with radiographic knee osteoarthritis progression: data from the Osteoarthritis Initiative Bone Ancillary Study. European Radiology. 2018 May 2. PMID: 29721684

12. Lo GH, Musa SM, Driban JB, Kriska AM, McAlindon TE, Souza RB, Petersen NJ, Storti KL, Eaton

CB, Hochberg MC, Jackson RD, Kwoh CK, Nevitt MC, Suarez-Almazor ME. Running does not increase symptoms or structural progression in people with knee osteoarthritis: data from the osteoarthritis initiative. Clinical Rheumatology. 2018 May 4. E-pub ahead of print.

13. Harkey MS, Price LL, McAlindon TE, Davis JE, Stout AC, Lu B, Zhang M, Eaton CB, Barbe MF, Lo

GH, Driban JB. Declining Walking Speed Associates with Increasing Bone Marrow Lesion Volume and Effusion Volume in Individuals with Accelerated Knee Osteoarthritis. Arthritis Care Res (Hoboken). 2018 Jun 8. doi: Epub ahead of print PMID: 29882630

Rashmi Maganti N/a Donald Marcus

1. Marcus DM. Acupuncture and sham acupuncture for pain relief. JAMA 2017; 318:1502-1503. PMID: 29049648

2. Marcus DM. Noninvasive treatments for acute, subacute and chronic low back pain. Ann Int

Med 2017; 167:832. PMID: 29204610

3. Marcus DM. Chondroitin sulfate for knee osteoarthritis Ann Rheum Dis 2018 Jun;77(6):e27. PMID: 28663310.

Frank Orson N/a Antony Rodriguez

1. Kadmon CS, Landers CT, Li HS, Watowich SS, Rodriguez A, King KY. MicroRNA-22 controls interferon alpha production and erythroid maturation in response to infectious stress in mice. Exp Hematol. 2017;56:7-15. Epub 2017/09/16. doi: 10.1016/j.exphem.2017.09.001. PubMed PMID: 28911907; PMCID: PMC5696003.

Roger Rossen

1. Li E, Tsai CL, Maskatia ZK, Kakkar E, Porter P, Rossen RD, Perusich S, Knight JM, Kheradmand F, Corry DB. Benefits of antifungal therapy in asthma patients with airway mycosis: A retrospective cohort analysis. Immun Inflamm Dis. 2018 Jun;6(2):264-275. Epub 2018 Mar 25. PMID: 29575717

Tiphanie Vogel

1. Orandi AB, Vogel TP, Keppel MP, Utterson EC, Cooper MA. Azathioprine-associated complete NK cell deficiency. Journal of Clinical Immunology(2017) 37:514.

2. Romberg N, Vogel TP, Canna SW. NLRC4 inflammasomopathies.Current Opinion in Allergy and

Clinical Immunology(2017) 6:398.

3. Xia J, Miller CA, Baty J, Ramesh A, Jotte MRM, Fulton RS, Vogel TP, Cooper MA, Walkovich KJ, Makaryan V, Bolyard AA, Dinauer MC, Wilson DB, Vlachos A, Myers KC, Rothbaum RJ, Bertuch AA, Dale DC, Shimamura A, Boxer LA, Link DC. Somatic mutations and clonal hematopoiesis in congenital neutropenia. Blood (2018) 131:408.

4. Fabre A, Marchal S, Forbes LR, Vogel TP, Barlogis V, Triolo V, Rohrlich P-S, Etienne B, Frankel D,

Ambrosetti D, Hoflack M, Baque M, Bosdure E, Baravalle M, Carsin A, Dubus J-C, Giovannini-Chami L. STAT3 GOF: a new kid on the block in interstitial lung diseases. American Journal of Respiratory and Critical Care Medicine(2018) 197:e22.

Li-yuan Yu-Lee

1. Zeng H, Ortiz A, Shen P-F, Cheng C-J, Lee Y-C, Yu G, Lin S-C, Yu-Lee L-Y and Lin S-H (2017). Angiomotin regulates prostate cancer cell proliferation by signaling through Hippo-YAP pathway. Oncotarget: 8:10145-10160. PMID: 28052036

2. Lin S-C, Lee Y-C, Yu G, Zhou X, Chu K, Murshed M, Le N-T, Abe J-I, Fujiwara K, Gallick GE,

deCrombrugghe B, Yu-Lee L-Y, Maity SN, and Lin S-H (2017). Endothelial-to-osteoblast conversion generates osteoblastic metastasis of prostate cancer. Developmental Cell 41:467-480. PMID: 28586644

3. Bilen M, Pan T, Lee Y-C, Lin S-C, Yu G, Pan J, Vykoukal J, Gray K, Satcher R, Gallick G, Yu-Lee L-Y

and Lin S-H. Proteomics profiling of exosomes from primary mouse osteoblasts under proliferation versus mineralization conditions and characterization of their uptake into prostate cancer cells (2017). Journal of Proteome Research 16:2709-2728. PMID: 28675788

4. Lockyer P, Mao H, Fan Q, Li L, Yu-Lee L-Y, Eissa NT, Patterson C, Xie L and Pi X (2017). LRP1-

dependent BMPER signaling regulates lipopolysaccharide-induced vascular inflammation. Arteriosclerosis Thrombosis and Vascular Biology 37:467-480. PMID: 28596374

5. Yu K-J, Li JK, Lee Y-C, Yu G, Lin S-C, Pan T, Satcher RL, Titus MA, Yu-Lee L-Y, Weng WH, Gallick GE

and Lin S-H (2017). Cabozantinib-induced osteoblast secretome promotes survival and migration of metastatic prostate cancer cells in bone. Oncotarget 8:74987-75006. PMID: 29088840

6. Pan T, Yu K-J, Bird J, Satcher R, Moon B, Gallick GE, Lin S-C, Jonasch E, Lewis V, Yu G, Wood C, Yu-

Lee L-Y, Song J, Tannir N, Lin P, and Lin S-H (2018). BIGH3 promotes osteolytic lesions in renal cell carcinoma bone metastasis by inhibiting osteoblast differentiation. Neoplasia 20:32-43. PMID: 29190493

7. Yu G, Cheng C-J, Lin S-C, Lee Y-C, Frigo D, Yu-Lee L-Y, Gallick GE, Titus M, Nutt L, and Lin S-H

(2018). Organelle-derived acetyl-CoA promotes prostate cancer cell survival, migration, and metastasis via activation of calmodulin kinase II. Cancer Research 78:2490-2502. PMID: 29535221

8. Yu-Lee L-Y, Yu G, Lee Y-C, Lin S-C, Pan J, Pan T, Yu K-J, Liu B, Creighton CJ, Rodriguez JC,

Villalobos PA, Wistuba II, de Nadal E, Posas F, Gallick GE and Lin S-H (2018). Osteoblast-secreted factors mediate dormancy of metastatic prostate cancer in the bone via activation of the TGFβRIII-p38MAPK-pS249/T252RB pathway. Cancer Research 78:2911-2924. PMID: 29514796

9. Lin S-C, Yu-Lee L-Y and Lin S-H (2018). Osteoblastic factors in prostate cancer bone metastasis. Current Osteoporosis Report. In press.

Books and book chapters Sandeep Agarwal N/a Joan Appleyard N/a David Corry Corry DB, Kheradmand F, Luong A, Pandit L. 41. Immunological mechanisms of airway diseases and pathways to therapy. In: Clinical Immunology. Ed: Rich RR, Fleisher TA, Shearer WT, Schroeder HW, Frew AJ, Weyand CM. Elsevier, London, UK, 2018, pp. 491-505 Sana Hasan N/a Onome Ifoeze (Whiteru) N/a Grace Lo N/a Rashmi Maganti N/a

Donald Marcus N/a Frank Orson N/a Antony Rodriguez N/a Roger Rossen N/a Tiphanie Vogel N/a Li-yuan Yu-Lee N/a B. Awards and honors Sandeep Agarwal Cullen Trust for Healthcare Endowed Chair in Immunology (2018) Joan Appleyard N/a David Corry R. Clarence and Irene H. Fulbright Chair in Pathology (March, 2018) Sana Hasan N/a Onome Ifoeze (Whiteru) N/a Grace Lo N/A Rashmi Maganti

N/a Donald Marcus N/a Frank Orson N/a Antony Rodriguez Gillson Longenbaugh Foundation Award (2018) Roger Rossen N/a Tiphanie Vogel The Kelly Award for Juvenile Arthritis Research (2018) Arthritis National Research Foundation Scholar (2018) Li-yuan Yu-Lee N/a C. Professional organization/association offices held Sandeep Agarwal American Association of Immunology – Member American College of Rheumatology – Member American Thoracic Society – Member Joan Appleyard American College of Rheumatology – Member Spondylitis Research and Treatment Network (SPARTAN) – Member David Corry American Association of Allergy, Asthma, and Immunology – Member American Clinical and Climatological Association – Member American Society for Clinical Investigation – Member Association of American Physicians – Member Society for Mucosal Immunology – Member Sana Hasan Allergy, Asthma & Immunology Society

The Greater Houston Allergy, Asthma & Immunology Society Onome Ifoeze (Whiteru) Alliance for Academic Internal Medicine – Member American College of Physicians – Member American College of Rheumatology – Member S.L.E. Lupus Foundation – Member Grace Lo American College of Rheumatology – Member Osteoarthritis Research Society International – Member Rashmi Maganti American College of Rheumatology – Member Donald Marcus N/a Frank Orson N/a Antony Rodriguez Genetics Society - Member Roger Rossen N/a Tiphanie Vogel American Academy of Pediatrics—Member American College of Rheumatology—Member

AMIGO Mentorship Program—Mentor and Mentee American Association of Immunologists--Member Childhood Arthritis and Rheumatology Research Alliance—Member Scientific Advisory Committee—Member Clinical Immunology Society—Member Federation of Clinical Immunology Societies—Member Li-yuan Yu-Lee N/a D. Editorial board memberships and editorial positions Sandeep Agarwal N/a

Joan Appleyard N/a David Corry N/a Sana Hasan N/a Onome Ifoeze (Whiteru) N/a Grace Lo Osteoarthritis and Cartilage – Editorial board member Rashmi Maganti N/a Donald Marcus N/a Frank Orson N/a Antony Rodriguez N/a Roger Rossen N/a Tiphanie Vogel Frontiers in Immunology, Primary Immunodeficiencies – Editorial board member Frontiers in Pediatrics, Pediatric Immunology – Editorial board member Li-yuan Yu-Lee N/a E. Grants

Sandeep Agarwal Grant Title: Cadherin-11 Regulation of Dermal Fibrosis and Macrophage Function

R01, 1R01AR062056-01A1 (Agarwal) Funding Agency: NIH/NIAMS Investigator Relationship: PI Direct Cost for Overall Period: $1,702,524 Period: 2012 - 2018 Grant Title: Targeting STAT3 in systemic sclerosis and dermal fibrosis (Agarwal) Funding Agency: Scleroderma Foundation, Established Investigator Award Investigator Relationship: PI Direct Cost for Overall Period: $150,000 Period: 2016 - 2018 Joan Appleyard N/a David Corry Grant Title: Fungal Pathogenesis of Moderate to Severe Asthma Funding Agency: NIH; AI135803 Investigator Relationship: PI (other PI: F. Kheradmand) Direct Cost for Overall Period: $1,688,425 Period: 03/2018-12/23 Grant Title: Immunology Scientist Training Grant Funding agency: NIH/NIAID AI053831 Investigator relationship: PI Direct costs for overall period: $1,941,558 Period: 2014-2019 Grant Title: Mechanism and function of Let-7, a novel modulator of Th17-dependent emphysema Funding agency: NIH/NHLBI HL140398 Investigator relationship: PI (other PI: A. Rodriguez) Direct costs for overall period: $1,250,000 Period: 2018-2023 Sana Hasan N/a Onome Ifoeze (Whiteru) N/a

Grace Lo Grant Title: Feasibility of a Novel Approach to Studying Early Knee Osteoarthritis: an Offspring Study R03 AR069323 (Lo) Funding Agency: NIH/NIAMS Investigator Relationship: PI Direct Cost for Overall Period: $201,825 Period: 3/1/16 - 11/30/18 Grant Title: Modifiable Risk Factors for Incident and Progressive Early Knee Osteoarthritis 1K23AR062127-01 (Lo) Funding Agency: NIH/NIAMS Investigator Relationship: PI Direct Cost for Overall Period: $612,500 Period: 4/1/2012 – 3/31/2018 (NCE) Rashmi Maganti N/a Donald Marcus N/a Frank Orson N/a Antony Rodriguez Grant Title: Role of let-7 microRNA in chronic obstructive pulmonary disease (Rodriguez) Funding Agency: Gillson Longenbaugh Foundation Award Investigator Relationship: PI Direct Cost for Overall Period: $69,000 Period: 09/2018-12/2019 Grant Title: Mechanism and function of let-7, a novel modulator of Th17-dependent emphysema R01HL140398-01A1 Funding Agency: NIH (NHLBI) Investigator Relationship: co-PI Direct Cost for Overall Period: $1,250,000 Period: 09/2018-09/2023 Received 13% Score (15% cutoff), Provisionally Funded

Roger Rossen N/a

Tiphanie Vogel Grant Title: BRIDGE, Baylor Rheumatology Initiative: Developing and Guiding Engagement(Vogel) Funding Agency: Rheumatology Research Foundation Medical Student Preceptorship Investigator Relationship: PI/Mentor Direct Cost for Overall Period: $1,000 Period: 07/2018-06/2019

Grant Title: BCM Clinical Site for an Undiagnosed Diseases Network (UDN)

1 U01 HG007709-01 (Brendan Lee) Funding Agency: NIH Investigator Relationship: Rheumatology Lead Direct Cost for Overall Period: $2,257,050 Period: 07/2014-03/2018 Grant Title: A Targeted Approach to Cytokine Blockade in Juvenile Arthritis (Vogel) Funding Agency: Thrasher Research Fund Investigator Relationship: PI Direct Cost for Overall Period: $25,000 Period: 07/2017-06/2019 Grant Title: Validating STAT3 as a Therapeutic Target in Arthritis (Vogel) Funding Agency: Arthritis National Research Foundation Grant Investigator Relationship: PI Direct Cost for Overall Period: $100,000 Period: 06/2018-05/2019 Li-yuan Yu-Lee Grant Title: Endothelial-to-osteoblast conversion in prostate cancer bone metastasis (Lin / Yu-Lee) Funding Agency: NIH Multi-PI RO1; CA174798-06A1 Investigator Relationship: PI (other PI: Lin, S.) Direct Cost for Overall Period: $1,125,000 Period: 12/01/2018-11/30/2023 Grant Title: Polo-like Kinase 1 as a Novel Molecular Target for the Treatment of Asthma (Yu-Lee) Funding Agency: Biology of Inflammation Center Investigator Relationship: PI Direct Cost for Overall Period: $20,000 Period: 10/01/2013 - 07/30/2019 Grant Title: Regulation of Dormancy of Metastatic Prostate Cancer Cells by Bone Microenvironment (Lin) Funding Agency: Cancer Prevention and Research Institute of Texas Investigator Relationship: Co-investigator

Direct Cost for Overall Period: $900,000 Period: 03/01/2015 - 08/31/2018

Infectious Diseases


of 17

Faculty

Abbas, Ume L. (MD) Al Mohajer, Mayar (MD, MBA, CAQ, FACP) Arya, Monisha (MD, MPH) Atmar, Robert L. (MD) Breaux, Kathrine (BS) Chan, Galant (MD) Chiao, Elizabeth Yu (MD, MPH) Chou, Andrew (MD) Dang, Bich (MD). Darouiche, Rabih (MD)*. DiNardo, Andrew (MD)* El Sahly, Hana (MD)* Flash, Charlene (MD) Giordano, Thomas P. (MD, MPH) Hamill, Richard J. (MD) Hemmige, Vagish (MD) Jaffe, Penny A (MD) Keitel, Wendy (MD)* Kutemi, Oyebunmi Mejia, Rojelio (MD)* Mendoza, Daniel (MD, PhD) Mindru, Cezarina (MD) Musher, Daniel M. (MD) Parkerson, George R. (MD, MPH) Patel, Shital (MD). Rodriguez-Barradas, Maria C. (MD) Rose, Stacey R. (MD) Serpa, Jose A. (MD, MS) Tabasi-Tavakoli, Shahriar (MD) Trautner, Barbara (MD, PhD)

Woc-Colburn, Laila E. (MD, DTM&H) Weatherhead, Jill (MD, MS, DTM&H, FAAP)* Young, Edward J. (MD) *secondary appointments

of 17

Contents

A. Publications ......................................................................................................... 4 B. Grants .................................................................................................................12

Publications

1. Zahid U, Sagar F, Al Mohajer M, Majeed A. Management of Recurrent Clostridium difficile Infection

During Intensive Chemotherapy and Stem Cell Transplantation for Leukemia: Case with Literature Review. Cureus. 2018 Apr 2;10(4).

2. Taweel I, Beatty N, Duarte A, Nix D, Matthias K, Al Mohajer M. Significance of bacteriuria in patients with end‐stage renal disease on hemodialysis. Avicenna J Med. 2018 Apr‐Jun;8(2):51‐54.

3. Beatty NL, Marquez J, Al Mohajer M. Skin Manifestations of Primary Vibrio vulnificus Septicemia. Am J Trop Med Hyg. 2017 Jul;97(1):1‐2

4. Ong E, Farran S, Salloum M, Gardner S, Giovinco N, Armstrong DG, Matthias KR,Nix DE, Al Mohajer M. Does Everything That's Counted Count? Value ofInflammatory Markers for Following Therapy and Predicting Outcome inDiabetic Foot Infection. Int J Low Extrem Wounds. 2017 Jun;16(2):104‐107

5. Eljaaly K, Alshehri S, Aljabri A, Abraham I, Al Mohajer M, Kalil AC, Nix DE.Clinical failure with and without empiric atypical bacteria coverage inhospitalized adults with community‐acquired pneumonia: a systematic reviewand meta‐analysis. BMC Infect Dis. 2017 Jun 2;17(1):385.

6. Arya M, Marek HG, Marren RE, Hemmige V, Street RL Jr, Giordano TP. Development and Evaluation of a Physician‐Targeted Video to Promote HIV Screening. Health Promot Pract. 2018 Jun 1:1524839918783742.

7. Phillips AL, Patel S, Kumar D, Arya M. Letter to the Editor Regarding "HIV Testing at Visits to Physicians' Offices in the U.S., 2009‐2012". Am J Prev Med. 2018 May;54(5):724‐725.

8. Baumann KE, Hemmige V, Kallen MA, Street RL, Giordano TP, Arya M. Whether Patients Want It or Not, Physician Recommendations Will Convince Them to Accept HIV Testing. J Int Assoc Provid AIDS Care. 2018 Jan‐Dec;17:23

9. Grigoryan L, Zoorob R, Shah J, Wang H, Arya M, Trautner BW. Antibiotic Prescribing for Uncomplicated Acute Bronchitis Is Highest in Younger Adults. Antibiotics (Basel). 2017 Oct 27;6(4).

10. Arya M, Huang A, Kumar D, Hemmige V, Street RL Jr, Giordano TP. The Promise of Patient‐Centered Text Messages for Encouraging HIV Testing in an Underserved Population. J Assoc Nurses AIDS Care. 2018 Jan ‐ Feb;29(1):101‐106.

11. Zhang HH, Cortés‐Penfield NW, Mandayam S, Niu J, Atmar RL, Wu E, Chen D, Zamani R, Shah MK. Dialysis Catheter‐Related Bloodstream Infections in Patients Receiving Hemodialysis on an Emergency‐Only Basis: A Retrospective Cohort Analysis. Clin Infect Dis. 2018 Jul 9.

12. Hu L, Sankaran B, Laucirica DR, Patil K, Salmen W, Ferreon ACM, Tsoi PS, Lasanajak Y, Smith DF, Ramani S, Atmar RL, Estes MK, Ferreon JC, Prasad BVV. Glycan recognition in globally dominant human rotaviruses. Nat Commun. 2018 Jul 6;9(1):2631. doi: 10.1038/s41467‐018‐05098‐4.

13. Cortes‐Penfield NW, Ramani S, Estes MK, Atmar RL. Prospects and Challenges in the Development of a Norovirus Vaccine. Clin Ther. 2017 Aug;39(8):1537‐1549Review.

14. Mulligan MJ, Stapleton JT, Keitel WA, Frey SE, Chen WH, Rouphael N, Edupuganti S, Beck A, Winokur PL, El Sahly HM, Patel SM, Atmar RL, Graham I, Anderson E, El‐Kamary SS, Pasetti MF, Sztein MB, Hill H, Goll JB; DMID 08‐0006 Tularemia Vaccine Study Group. Tularemia vaccine: Safety, reactogenicity, "Take" skin reactions, and antibody responses following vaccination with a new lot of the Francisella tularensis live vaccine strain ‐ A phase 2 randomized clinical Trial. Vaccine 35:4730‐7, 2017 Jul 24

of 17

15. Sharma S, Carlsson B, Czakó R, Vene S, Haglund M, Ludvigsson J, Larson G, Hammarström L, Sosnovtsev SV, Atmar RL, Green KY, Estes MK, Svensson L. Human Sera Collected between 1979 and 2010 Possess Blocking‐Antibody Titers to Pandemic GII.4 Noroviruses Isolated over Three Decades. J Virol. 2017 Jun 26;91(14). Print 2017 Jul 15.

16. Shanker S, Hu L, Ramani S, Atmar RL, Estes MK, Venkataram Prasad BV. Structural features of glycan recognition among viral pathogens. Curr Opin Struct Biol, 44:211‐218, 2017 epub 2017 Jun 4

17. Cortes‐Penfield NW, Ramani S, Estes MK, Atmar RL. Prospects and challenges in the development of a norovirus vaccine. Clin Ther, 39:1537‐49, 2017 epub 2017 Jul 26

18. Serpa JA, Rueda AM, Somasunderam A, Utay NS, Lewis D, Couturier JP, Breaux KG, Rodriguez-Barradas M. Long-term Use of Proton Pump Inhibitors Is Associated With Increased Microbial Product Translocation, Innate Immune Activation, and Reduced Immunologic Recovery in Patients With Chronic Human Immunodeficiency Virus-1 Infection. Clin Infect Dis. 2017 Oct 30; 65(10):1638-1643.

19. Butame SA, Lawler S, Hicks JT, Wilkerson JM, Hwang LY, Baraniuk S, Ross MW, Chiao EY, Nyitray AG. A qualitative investigation among men who have sex with men on the acceptability of performing a self‐ or partner anal exam to screen for anal cancer. Cancer Causes Control. 2017 Oct;28(10):1157‐1166.

20. Deshmukh AA, Cantor SB, Fenwick E, Chiao EY, Nyitray AG, Stier EA, Goldstone SE, Wilkin T, Chhatwal J. Adjuvant HPV vaccination for anal cancer prevention in HIV‐positive men who have sex with men: The time is now. Vaccine. 2017 Sep 12;35(38):5102‐5109.

21. Royse KE, El Chaer F, Amirian ES, Hartman C, Krown SE, Uldrick TS, Lee JY, Shepard Z, Chiao EY. Disparities in Kaposi sarcoma incidence and survival in the United States: 2000‐2013. PLoS One. 2017 Aug 22;12(8):e0182750.

22. Nyitray AG, Hicks JT, Hwang LY, Baraniuk S, White M, Millas S, Onwuka N, Zhang X, Brown EL, Ross MW, Chiao EY. A phase II clinical study to assess the feasibility of self and partner anal examinations to detect anal canal abnormalities including anal cancer. Sex Transm Infect. 2018 Mar;94(2):124‐130.

23. Deshmukh AA, Chiao EY, Cantor SB, Stier EA, Goldstone SE, Nyitray AG, Wilkin T, Wang X, Chhatwal J. Management of precancerous anal intraepithelial lesions in human immunodeficiency virus‐positive men who have sex with men: Clinical effectiveness and cost‐effectiveness. Cancer. 2017 Dec 1;123(23):4709‐4719.

24. Sonawane K, Suk R, Chiao EY, Chhatwal J, Qiu P, Wilkin T, Nyitray AG, Sikora AG, Deshmukh AA. Oral Human Papillomavirus Infection: Differences in Prevalence Between Sexes and Concordance With Genital Human Papillomavirus Infection, NHANES 2011 to 2014. Ann Intern Med. 2017 Nov 21;167(10):714‐724.

25. Stier EA, Chiao EY. Anal Cancer and Anal Cancer precursors in Women with a History of HPV‐Related Dysplasia and Cancer. Semin Colon Rectal Surg. 2017 Jun;28(2):97‐101.

26. Chang E, Rivero G, Patel NR, Chiao EY, Lai S, Bajaj K, Mbue JE, Yellapragada SV. HIV‐related Refractory Hodgkin Lymphoma: A Case Report of Complete Response to Nivolumab. Clin Lymphoma Myeloma Leuk. 2018 Feb;18(2): e143‐e146

27. Hwang JP, Ahmed S, Ariza‐Heredia EJ, Duan Z, Zhao H, Schmeler KM, Ramondetta L, Parker SL, Suarez‐Almazor ME, Ferrajoli A, Shih YT, Giordano SH, Chiao EY. Low Rate of Cervical Cancer Screening among Women with Hematologic Malignancies after Stem Cell Transplant. Biol Blood Marrow Transplant. 2018 May;24(5):1094‐1098.

28. Cranston RD, Cespedes MS, Paczuski P, Yang M, Coombs RW, Dragavon J, Saah A, Godfrey C, Webster‐Cyriaque JY, Chiao EY, Bastow B, Wilkin T; ACTG 5298 Study Team. High Baseline Anal Human Papillomavirus and Abnormal Anal Cytology in a Phase 3 Trial of the Quadrivalent Human Papillomavirus Vaccine in Human Immunodeficiency Virus‐Infected Individuals Older Than 26

Years: ACTG 5298. Sex Transm Dis. 2018 Apr;45(4):266‐271. 29. Wilkin TJ, Chen H, Cespedes MS, Leon‐Cruz JT, Godfrey C, Chiao EY, Bastow B, Webster‐Cyriaque J,

Feng Q, Dragavon J, Coombs RW, Presti RM, Saah A, Cranston RD. A randomized, placebo‐controlled trial of the quadrivalent HPV vaccine in HIV‐infected adults age 27 years or older: AIDS Clinical Trials Group protocol A5298. Clin Infect Dis. 2018 Apr 5.

30. Thrift AP, Chiao EY. Are Non‐HIV Malignancies Increased in the HIV‐Infected Population? Curr Infect Dis Rep. 2018 May 26;20(8):22. Review.

31. Deshmukh AA, Shirvani SM, Likhacheva A, Chhatwal J, Chiao EY, Sonawane K The Association Between Dietary Quality and Overall and Cancer‐Specific Mortality Among Cancer Survivors, NHANES III. JNCI Cancer Spectr. 2018 Apr;2(2): pky022.

32. Chang E, Mapakshi SR, Mbang P, El‐Mallawany NK, Kramer JR, White DL, Chiao EY. The impact of protease inhibitors on HIV‐associated Kaposi sarcoma incidence: a systematic review. J Acquir Immune Defic Syndr. 2018 Jul 6. [Epub ahead of print]

33. Chang E, Sabichi AL, Kramer JR, Hartman C, Royse KE, White DL, Patel NR, Richardson P, Yellapragada SV, Garcia JM, Chiao EY. Nivolumab Treatment for Cancers in the HIV‐infected Population.. J Immunother. 2018 Jul 16.

34. Chou A, Trautner BW. Efficacy and Safety of short courses of antibiotic therapy for bacteremia caused by Enterobacteriaceae. Clin Infect Dis. 2018 Jul 18;67(3):482‐483

35. Dang BN, Graham DY. It is time to rethink H. pylori therapy. J Gastrointestin Liver Dis. 2017 Jun;26(2):115‐117.

36. Stewart DE, Dang BN, Trautner B, Cai C, Torres S, Turner T. Assessing residents' knowledge of patient satisfaction: a cross‐sectional study at a large academic medical centre. BMJ Open. 2017 Aug 21;7(8): e017100.

37. Dandachi D, Dang BN, Wilson Dib R, Friedman H, Giordano T. Knowledge of HIV Testing Guidelines Among US Internal Medicine Residents: A Decade After the Centers for Disease Control and Prevention's Routine HIV Testing Recommendations. AIDS Patient Care STDS. 2018 May;32(5):175‐180.

38. Voigt J, Mosier M, Darouiche R. Private Rooms in Low Acuity Settings: A Systematic Review of the Literature. HERD. 2018 Jan;11(1):57‐74. doi: 10.1177/1937586717702597. Epub 2017 Aug 23.

39. Zhu Z, Yu F, Chen H, Wang J, Lopez AI, Chen Q, Li S, Long Y, Darouiche RO, Hull RA, Zhang L, Cai C. Coating of silicone with mannoside‐PAMAM dendrimers to enhance formation of non‐pathogenic Escherichia coli biofilms against colonization of uropathogens. Acta Biomater. 2017 Dec; 64:200‐210.

40. Boulavsky JL, Wright HM, Rodriguez‐Waitkus PM, DiNardo AR, Woc‐Colburn LE, Dao H Jr. Sporotrichoid pattern of Mycobacterium chelonae‐abscessus infection. Cutis. 2017 Sep;100(3): E4‐E5.

41. DiNardo AR, Kay AW, Maphalala G, Harris NM, Fung C, Mtetwa G, Ustero P, Dlamini S, Ha N, Graviss EA, Mejia R, Mandalakas AM. Diagnostic and Treatment Monitoring Potential of A Stool‐Based Quantitative Polymerase Chain Reaction Assay for Pulmonary Tuberculosis. Am J Trop Med Hyg. 2018 Aug;99(2):310‐316.

42. DiNardo AR, Nishiguchi T, Mace EM, Rajapakshe K, Mtetwa G, Kay A, Maphalala G, Secor WE, Mejia R, Orange JS, Coarfa C, Bhalla KN, Graviss EA, Mandalakas AM, Makedonas G. Schistosomiasis Induces Persistent DNA Methylation and Tuberculosis‐Specific Immune Changes. J Immunol. 2018 Jul 1;201(1):124‐133.

43. El Sahly H, Udayamurthy M, Parkerson G, Hasbun R. Survival of an AIDS patient after infection with Acanthamoeba sp. of the central nervous system. Infection. 2017 Oct;45(5):715‐718.

44. Mulligan MJ, Stapleton JT, Keitel WA, Frey SE, Chen WH, Rouphael N, Edupuganti S, Beck A, Winokur PL, El Sahly HM, Patel SM, Atmar RL, Graham I, Anderson E, El‐Kamary SS, Pasetti MF,

of 17

Sztein MB, Hill H, Goll JB; DMID 08‐0006 Tularemia Vaccine Study Group. Tularemia vaccine: Safety, reactogenicity, "Take" skin reactions, and antibody responses following vaccination with a new lot of the Francisella tularensis live vaccine strain ‐ A phase 2 randomized clinical Trial. Vaccine. 2017 Aug 24;35(36):4730‐4737.

45. Jackson LA, El Sahly HM, George S, Winokur P, Edwards K, Brady RC, Rouphael N, Keitel WA, Mulligan MJ, Burton RL, Nakamura A, Ferreria J, Nahm MH. Randomized clinical trial of a single versus a double dose of 13‐valent pneumococcal conjugate vaccine in adults 55 through 74 years of age previously vaccinated with 23‐valent pneumococcal polysaccharide vaccine. Vaccine. 2018 Jan 29;36(5):606‐614.

46. Hemmige V, Flash CA, Carter J, Giordano TP, Zerai T. Single tablet HIV regimens facilitate virologic suppression and retention in care among treatment naïve patients. AIDS Care. 2018 Aug;30(8):1017‐1024

47. Flash CA, Adegboyega OO, Yu X, Avalos C, Johnson S, Mayer KH, Giordano TP. Correlates of Linkage to HIV Preexposure Prophylaxis Among HIV‐Testing Clients. J Acquir Immune Defic Syndr. 2018 Apr 1;77(4):365‐372.

48. Fujimoto K, Flash CA, Kuhns LM, Kim JY, Schneider JA. Social networks as drivers of syphilis and HIV infection among young men who have sex with men. Sex Transm Infect. 2018 Aug;94(5):365‐371.

49. Flash CA, Frost ELT, Giordano TP, Amico KR, Cully JA, Markham CM. HIV Pre‐exposure Prophylaxis Program Implementation Using Intervention Mapping. Am J Prev Med. 2018 Apr;54(4):519‐529. doi: 10.1016/j.amepre.2017.12.015. Epub 2018 Feb 9.

50. Mayer KH, Chan PA, R Patel R, Flash CA, Krakower DS. Evolving Models and Ongoing Challenges for HIV Preexposure Prophylaxis Implementation in the United States. J Acquir Immune Defic Syndr. 2018 Feb 1;77(2):119‐127.

51. Marks G, O'Daniels C, Grossman C, Crepaz N, Rose CE, Patel U, Stirratt MJ, Gardner LI, Cachay ER, Mathews WC, Drainoni ML, Sullivan M, Bradley‐Springer L, Corwin M, Gordon C, Rodriguez A, Dhanireddy S, Giordano TP. Evaluation of a computer‐based and counseling support intervention to improve HIV patients' viral loads. AIDS Care. 2018 Aug 16:1‐9.

52. Arya M, Marek HG, Marren RE, Hemmige V, Street RL Jr, Giordano TP. Development and Evaluation of a Physician‐Targeted Video to Promote HIV Screening. Health Promot Pract. 2018 Jun 1:1524839918783742. [Epub ahead of print]

53. Giordano TP. Strategies for Linkage to and Engagement With Care: Focus on Intervention. Top Antivir Med. 2018 Jun;26(2):62‐65.

54. Gardner LI, Marks G, Patel U, Cachay E, Wilson TE, Stirratt M, Rodriguez A, Sullivan M, Keruly JC, Giordano TP. Gaps Up To 9 Months Between HIV Primary Care Visits Do Not Worsen Viral Load. AIDS Patient Care STDS. 2018 Apr;32(4):157‐164. doi: 10.1089/apc.2018.0001.

55. Hemmige V, Flash CA, Carter J, Giordano TP, Zerai T. Single tablet HIV regimens facilitate virologic suppression and retention in care among treatment naïve patients. AIDS Care. 2018 Aug;30(8):1017‐1024.

56. Flash CA, Adegboyega OO, Yu X, Avalos C, Johnson S, Mayer KH, Giordano TP. Correlates of Linkage to HIV Preexposure Prophylaxis Among HIV‐Testing Clients. J Acquir Immune Defic Syndr. 2018 Apr 1;77(4):365‐372.

57. Flash CA, Frost ELT, Giordano TP, Amico KR, Cully JA, Markham CM. HIV Pre‐exposure Prophylaxis Program Implementation Using Intervention Mapping. Am J Prev Med. 2018 Apr;54(4):519‐529. doi: 10.1016/j.amepre.2017.12.015. Epub 2018 Feb 9.

58. White DAE, Giordano TP, Pasalar S, Jacobson KR, Glick NR, Sha BE, Mammen PE, Hunt BR, Todorovic T, Moreno‐Walton L, Adomolga V, Feaster DJ, Branson BM. Acute HIV Discovered During Routine HIV Screening With HIV Antigen‐Antibody Combination Tests in 9 US Emergency Departments. Ann Emerg Med. 2018 Jul;72(1):29‐40.e2.

59. Stirratt MJ, Marks G, O'Daniels C, Cachay ER, Sullivan M, Mugavero MJ, Dhanireddy S, Rodriguez AE, Giordano TP. Characterising HIV transmission risk among US patients with HIV in care: a cross‐sectional study of sexual risk behaviour among individuals with viral load above 1500 copies/mL. Sex Transm Infect. 2018 May;94(3):206‐211.


61. Davila JA, Hartman C, Cully J, Stanley M, Amico KR, Soriano E, Minick S, May SB, Giordano TP. Feasibility of identifying out of care HIV‐positive patients in a hospital setting and enrolling them in a retention intervention. HIV Clin Trials. 2017 Mar;18(2):75‐82.

62. Allencherril J, Bruera S, Allencherril R, Hamill RJ. Lone Hepatocellular Carcinoma: An Isolated Chest Wall Malignancy. Case Rep Med. 2017;2017:3531823.

63. Ashong CN, Hunter AS, Mansouri MD, Cadle RM, Hamill RJ, Musher DM. Adherence to clinical practice guidelines for the treatment of candidemia at a Veterans Affairs Medical Center. Int J Health Sci (Qassim). 2017 Jul‐Sep;11(3):18‐23.

64. Arya M, Marek HG, Marren RE, Hemmige V, Street RL Jr, Giordano TP. Development and Evaluation of a Physician‐Targeted Video to Promote HIV Screening. Health Promot Pract. 2018 Jun 1:1524839918783742.

65. Hemmige V, Flash CA, Carter J, Giordano TP, Zerai T. Single tablet HIV regimens facilitate virologic suppression and retention in care among treatment naïve patients. AIDS Care. 2018 Aug;30(8):1017‐1024

66. Baumann KE, Hemmige V, Kallen MA, Street RL, Giordano TP, Arya M.Whether Patients Want It or Not, Physician Recommendations Will Convince Them to Accept HIV Testing. J Int Assoc Provid AIDS Care. 2018 Jan‐Dec;17:2325957417752258

67. Kamath RS, Sudhakar D, Gardner JG, Hemmige V, Safar H, Musher DM. Guidelines vs Actual Management of Skin and Soft Tissue Infections in the Emergency Department. Open Forum Infect Dis. 2018 Jan 12;5(1)

68. Patel S, Hemmige V, Street RL Jr, Viswanath K, Arya M. Activating Racial and Ethnic Minorities to Engage in Preventive Health: Patient Preferences for Health Reminders. J Particip Med. 2017;9. pii: e8. Epub 2017 Apr 22.

69. Vaughan EM, Johnston CA, Hyman DJ, Hernandez DC, Hemmige V, Foreyt JP. Dual Therapy Appears Superior to Monotherapy for Low‐Income Individuals With Newly Diagnosed Type 2 Diabetes. J Prim Care Community Health. 2017 Oct;8(4):305‐311.


71. Afzal Z, Kallumadanda S, Wang F, Hemmige V, Musher D. Acute Febrile Illness and Complications Due to Murine Typhus, Texas, USA1,2. Emerg Infect Dis. 2017 Aug;23(8):1268‐1273

72. DiNardo AR, Kay AW, Maphalala G, Harris NM, Fung C, Mtetwa G, Ustero P, Dlamini S, Ha N, Graviss EA, Mejia R, Mandalakas AM. Diagnostic and Treatment Monitoring Potential of A Stool‐Based Quantitative Polymerase Chain Reaction Assay for Pulmonary Tuberculosis. Am J Trop Med Hyg. 2018 Aug;99(2):310‐316.

73. DiNardo AR, Nishiguchi T, Mace EM, Rajapakshe K, Mtetwa G, Kay A, Maphalala G, Secor WE, Mejia R, Orange JS, Coarfa C, Bhalla KN, Graviss EA, Mandalakas AM, Makedonas G. Schistosomiasis Induces Persistent DNA Methylation and Tuberculosis‐Specific Immune Changes. J Immunol. 2018 Jul 1;201(1):124‐133.

74. Diemert D, Campbell D, Brelsford J, Leasure C, Li G, Peng J, Zumer M, Younes N, Bottazzi ME, Mejia

of 17

R, Pritchard DI, Hawdon JM, Bethony JM. Controlled Human Hookworm Infection: Accelerating Human Hookworm Vaccine Development. Open Forum Infect Dis. 2018 Apr 19;5(5): ofy083.

75. Papaiakovou M, Pilotte N, Grant JR, Traub RJ, Llewellyn S, McCarthy JS, Krolewiecki AJ, Cimino R, Mejia R, Williams SA. A novel, species‐specific, real‐time PCR assay for the detection of the emerging zoonotic parasite Ancylostoma ceylanicum in human stool. PLoS Negl Trop Dis. 2017 Jul 10;11(7):e0005734.

76. Weatherhead J, Cortés AA, Sandoval C, Vaca M, Chico M, Loor S, Cooper PJ, Mejia R. Comparison of Cytokine Responses in Ecuadorian Children Infected with Giardia, Ascaris, or Both Parasites. Am J Trop Med Hyg. 2017 Jun;96(6):1394‐1399.

77. Weatherhead JE, Hotez PJ, Mejia R. The Global State of Helminth Control and Elimination in Children. Pediatr Clin North Am. 2017 Aug;64(4):867‐877. Review.

78. McKenna ML, McAtee S, Bryan PE, Jeun R, Ward T, Kraus J, Bottazzi ME, Hotez PJ, Flowers CC, Mejia R. Human Intestinal Parasite Burden and Poor Sanitation in Rural Alabama. Am J Trop Med Hyg. 2017 Nov;97(5):1623‐1628.

79. Pirozzi CS, Mendoza DL, Xu Y, Zhang Y, Scholand MB, Baughman RP. Short‐Term Particulate Air Pollution Exposure is Associated with Increased Severity of Respiratory and Quality of Life Symptoms in Patients with Fibrotic Sarcoidosis. Int J Environ Res Public Health. 2018 May 26;15(6). pii: E1077.

80. Mitchell LE, Lin JC, Bowling DR, Pataki DE, Strong C, Schauer AJ, Bares R, Bush SE, Stephens BB, Mendoza D, Mallia D, Holland L, Gurney KR, Ehleringer JR. Long‐term urban carbon dioxide observations reveal spatial and temporal dynamics related to urban characteristics and growth. Proc Natl Acad Sci U S A. 2018 Mar 20;115(12):2912‐2917.

81. So AP, Vilborg A, Bouhlal Y, Koehler RT, Grimes SM, Pouliot Y, Mendoza D, Ziegle J, Stein J, Goodsaid F, Lucero MY, De La Vega FM, Ji HP. A robust targeted sequencing approach for low input and variable quality DNA from clinical samples. NPJ Genom Med. 2018 Jan 15;3:2.

82. Yagiz K, Rodriguez‐Aguirre ME, Lopez Espinoza F, Montellano TT, Mendoza D, Mitchell LA, Ibanez CE, Kasahara N, Gruber HE, Jolly DJ, Robbins JM. A Retroviral Replicating Vector Encoding Cytosine Deaminase and 5‐FC Induces Immune Memory in Metastatic Colorectal Cancer Models. Mol Ther Oncolytics. 2017 Dec 5;8:14‐26..

83. Hofacre A, Yagiz K, Mendoza D, Lopez Espinoza F, Munday AW, Burrascano C, Singer O, Gruber HE, Jolly DJ, Lin AH. Efficient Therapeutic Protein Expression Using Retroviral Replicating Vector with 2A Peptide in Cancer Models. Hum Gene Ther. 2018 Apr;29(4):437‐451.

84. Marcantonio YC, Kulkarni PA, Sachs S, Ting K, Lee J, Mendoza D. Disseminated Pasteurella multocida infection: Cellulitis, osteomyelitis, and myositis. IDCases. 2017 Sep 15;10:68‐70.

85. Mitchell LA, Lopez Espinoza F, Mendoza D, Kato Y, Inagaki A, Hiraoka K, Kasahara N, Gruber HE, Jolly DJ, Robbins JM. Toca 511 gene transfer and treatment with the prodrug, 5‐fluorocytosine, promotes durable antitumor immunity in a mouse glioma model. Neuro Oncol. 2017 Jul 1;19(7):930‐939.

86. Kumar D, Cortés‐Penfield NW, El‐Haddad H, Musher DM. Bowel Perforation Resulting in Necrotizing Soft‐Tissue Infection of the Abdomen, Flank, and Lower Extremities. Surg Infect (Larchmt). 2018 Jul;19(5):467‐472.

87. Lin WV, Kruse RL, Yang K, Musher DM. Diagnosis and management of pulmonary infection due to Rhodococcus equi. Clin Microbiol Infect. 2018 May 16. pii: S1198‐743X(18)30400‐2. Review.

88. Kamat IS, Ramachandran V, Eswaran H, Abers MS, Musher DM. Low procalcitonin, community acquired pneumonia, and antibiotic therapy. Lancet Infect Dis. 2018 May;18(5):496‐497.

89. Gardner JG, Rueda AM, Musher DM. Acute Onset of Pneumococcal Pneumonia Following Instrumentation of the Respiratory Tract. Open Forum Infect Dis. 2018 Apr 2;5(4).

90. Musher DM, Abers MS, Bartlett JG. Reply to Horowitz. Clin Infect Dis. 2018 Jul 18;67(3):482.

91. Musher DM. Polysaccharide Antibody Deficiency: Specific or General? Clin Infect Dis. 2018 Feb 1;66(4):636‐637.

92. Abers MS, Musher DM. Procalcitonin as a Marker of Etiology in Community‐Acquired Pneumonia. Clin Infect Dis. 2018 May 2;66(10):1639.

93. Kamath RS, Sudhakar D, Gardner JG, Hemmige V, Safar H, Musher DM. Guidelines vs Actual Management of Skin and Soft Tissue Infections in the Emergency Department.

94. Open Forum Infect Dis. 2018 Jan 12;5(1) 95. Musher DM, Abers MS, Bartlett JG. Evolving Understanding of the Causes of Pneumonia in Adults,

With Special Attention to the Role of Pneumococcus. Clin Infect Dis.2017 Oct 30;65(10):1736‐1744. 96. Ashong CN, Hunter AS, Mansouri MD, Cadle RM, Hamill RJ, Musher DM Adherence to clinical

practice guidelines for the treatment of candidemia at a Veterans Affairs Medical Center. Int J Health Sci (Qassim). 2017 Jul‐Sep;11(3):18‐23.

97. Gardner JG, Bhamidipati DR, Rueda AM, Nguyen DTM, Graviss EA, Musher DM. White Blood Cell Counts, Alcoholism, and Cirrhosis in Pneumococcal Pneumonia. Open Forum Infect Dis. 2017 Feb 24;4(2)

98. Kaka AS, Filice GA, Kuskowski M, Musher DM. Does active hepatitis C virus infection increase the risk for infection due to Staphylococcus aureus? Eur J Clin Microbiol Infect Dis. 2017 Jul;36(7):1217‐1223.

99. El Sahly H, Udayamurthy M, Parkerson G, Hasbun R. Survival of an AIDS patient after infection with Acanthamoeba sp. of the central nervous system. Infection. 2017 Oct;45(5):715-718

100. Mgbere O, Khuwaja S, Vigil KJ, Patel SM, Wang J, Essien EJ. Sources of clinical information used in HIV care and treatment: Are providers' choices related to their demographic and practice characteristics? Health Informatics J. 2018 Aug 7:1460458218788906.

101. Chung C, Patel S, Lee R, Fu L, Reilly S, Ho T, Lionetti J, George MD, Taylor P. Implementation of an integrated computerized prescriber order‐entry system for chemotherapy in a multisite safety‐net health system. Am J Health Syst Pharm. 2018 Mar 15;75(6):398‐406. Erratum in: Am J Health Syst Pharm. 2018 Apr 15;75(8):504.

102. Lai L, Rouphael N, Xu Y, Natrajan MS, Beck A, Hart M, Feldhammer M, Feldpausch A, Hill C, Wu H, Fairley JK, Lankford‐Turner P, Kasher N, Rago P, Hu YJ, Edupuganti S, Patel SM, Murray KO, Mulligan MJ; Emory Zika Patient Study Team. Innate, T‐, and B‐Cell Responses in Acute Human Zika Patients. Clin Infect Dis. 2018 Jan 6;66(1):1‐10.

103. Edupuganti S, Natrajan MS, Rouphael N, Lai L, Xu Y, Feldhammer M, Hill C, Patel SM, Johnson SJ, Bower M, Gorchakov R, Berry R, Murray KO, Mulligan MJ. Biphasic Zika Illness With Rash and Joint Pain. Open Forum Infect Dis. 2017 Jun 22;4(3)

104. Mulligan MJ, Stapleton JT, Keitel WA, Frey SE, Chen WH, Rouphael N, Edupuganti S, Beck A, Winokur PL, El Sahly HM, Patel SM, Atmar RL, Graham I, Anderson E, El‐Kamary SS, Pasetti MF, Sztein MB, Hill H, Goll JB; DMID 08‐0006 Tularemia Vaccine Study Group. Tularemia vaccine: Safety, reactogenicity, "Take" skin reactions, and antibody responses following vaccination with a new lot of the Francisella tularensis live vaccine strain ‐ A phase 2 randomized clinical Trial. Vaccine. 2017 Aug 24;35(36):4730‐4737.

105. Waggoner JJ, Rouphael N, Xu Y, Natrajan M, Lai L, Patel SM, Levit RD, Edupuganti S, Mulligan MJ. Pericarditis Associated With Acute Zika Virus Infection in a Returning Traveler. Open Forum Infect Dis. 2017 May 18;4(2).

106. Riedl MA, Banerji A, Busse PJ, Johnston DT, Davis‐Lorton MA, Patel S, Parr H, Chiao J, Watson DJ, Burrell E, Machnig T. Patient satisfaction and experience with intravenously administered C1‐inhibitor concentrates in the United States. Ann Allergy Asthma Immunol. 2017 Jul;119(1):59‐64.

107. Weatherhead J, Cortés AA, Sandoval C, Vaca M, Chico M, Loor S, Cooper PJ, Mejia R.

of 17

Comparison of Cytokine Responses in Ecuadorian Children Infected with Giardia, Ascaris, or Both Parasites. Am J Trop Med Hyg. 2017 Jun;96(6):1394‐1399.

108. Weatherhead JE, Hotez PJ, Mejia R. The Global State of Helminth Control and Elimination in Children. Pediatr Clin North Am. 2017 Aug;64(4):867‐877. Review.

Grants

Al Mohaher: Vernon & Virginia Furrow Award was granted by the Academy of Medical Education Scholars (AMES) Technical title of project: Improving the Knowledge and Attitudes of Medical Students and Physicians Regarding Appropriate Use of Antibiotic for Respiratory Infections Through Online CME Modules Al Mohaher: University of Arizona Medical Center‐University Campus Medical Staff. Technical title of project: Improving the Knowledge of Students and Physicians Regarding Appropriate Empiric Antibiotic Use Arya (PI): Designing a HIV Testing Campaign for Health Centers Serving African‐Americans Source: National Institute of Mental Health, NIH, K23 Career Development Award. Dates of funding: 04/01/2012‐03/31/2017 Atmar: Molecular Dissection of Norovirus Replication and Pathogenesis to Develop Therapeutic. NIH/NIAID: P01 AI057788 (PI: MK Estes), 6/1/2015 ‐ 5/31/2020. Role, Project 1 co‐PI Atmar: Evaluation of Control Measures Against Diseases Other than AIDS. NIH/NIAID: HHSN272201300015I (PI: H El Sahly), 09/16/2013‐09/15/2023, Role: Investigator, PI on clinical protocols Atmar: Research Training in Infections and Immunity. NIH/NIAID: T32 AI055413 (PI: RL Atmar), 6/1/2014 – 5/31/2019, Role: Principal Investigator Chiao: 1R01 CA206476‐02 (PI – Chiao) NIH (PQ3) Identifying Novel Pharmacologic Risk factors for Common Non‐AIDS Defining Cancers in Individuals with Well‐controlled HIV Infection The goal of this project is to evaluate whether specific classes of medications increase or decrease the risk for common NADCs in a cohort of well‐treated/well‐controlled patients with HIV infection. Role: Principal Investigator Chiao: NIH U24MH100930‐01 (Gelman)NIH/NIMH/NINDS. Texas Repository for AIDS Neuropathogenesis research. The goal of this project is to acquire, store and conduct research on the neurological and mental health outcomes of HIV‐infected individuals. Role: Co‐Investigator Chiao: NIH UM1CA181255 (Ittman) NCI. AIDS Cancer Specimen Registry (ACSR) The goal of this project is to acquire, store and equitably distribute tumor tissues and biological fluids from patients with HIV‐associated malignancies. Role: Co‐Investigator Chiao: NIH 2U01CA121947‐04 (PI – Mitsuyasu) NIH. AIDS Malignancy Consortium The goal of this project is to conduct clinical trials among indiviauls with HIV‐associated malignanices. Role: Co‐Investigator Chiao: CFAR mentored CINHR (PI – Thrift) NIH. Risk and Predictors of Esophageal and Esophagogastric Junction Adenocarcinomas in HIV‐Infected Individuals. The goal of this study is to examine risk of and mortality from esophageal (EAC) and esophagogastric junction (EGJAC)

of 17

adenocarcinoma in HIV infection, and to identify predictors of these cancers in HIV‐infected individuals. Role: Mentor Chiao: CA215403‐01 (PI – Nyitray) NIH Annual anal sampling using DNA screecing to identify men who have sex with men (MSM) at increased risk for anal cancer. The goal of this study is to determine MSM at increased risk for anal cancer by conducting annual anal screening tests using novel DNA testing techniques. Role: Co‐Investigator Dang: Patient satisfaction, retention in HIV care, and adherence to antiretroviral therapy K23 MH100965‐01A1. $901,800.00 (07/01/2014 – present) Grant funding from the National Institute of Health. This study will enroll 400 patients and follow them to see if patients with better care experiences are more likely to stay in HIV care and take their HIV medicines. Darouiche: Air Barrier System for the Prevention of Prosthesis‐related Infections.” Small Business Innovation Research (SBIR). Grant no. 2R44GM095005‐05. Study period: 09/15/2014‐09/14/2018. Principal Investigator. Overall cost = $7,004 peryear. National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS). DiNardo: Helminth Induced Alterations in BCG Immunity: 201602018: Evaluation of Helminth alterations in BCG vaccine immunity in Nigeria. In this PEPFAR funded study, Dr. DiNardo’s role is to evaluate the epigenetic and immune effect of simultaneous versus delayed de‐worming before BCG revaccination among a helminth‐infected population. El Sahly: Vaccine and Treatment Evaluation Units, Contract: National Institutes of Health, contract # HHSN272201300015I, Role: Principal Investigator, Effort: 0.6 calendar months, Dates: 09/16/2013‐09/18/2023 Giordano: A Multi‐level Intervention to Improve Cancer Care for Hepatocellular Carcinoma. Source: VA Health Services Research and Development. Role: Co‐investigator (Davila, BCM). Dates of Funding: 10/1/15 – 6/30/19. Direct cost: $1,997,000 total over 4 years. VA Merit Award Grant ‐ IIR 14‐101 Giordano: Identifying novel pharmacologic risk factors for common non‐AIDS defining cancers in individuals with well‐controlled HIV Infection. Source: National Institutes of Health Role: Co‐investigator (Chiao, BCM). Dates of Funding: 07/2016‐03/2021. Direct cost: $1,968,930 total over 5 years. Grant ‐ 1R01 CA206476‐01 Giordano: PREVENT HCC – Through Screening, Vaccination and Treatment of Viral Hepatitis Source: Cancer Prevention and Research Institute of Texas (CPRIT). Role: Co‐investigator (El‐Serag and Thrift, BCM). Dates of Funding: 01/2016‐08/2019. Direct cost: $1,492,052 total over 3 years. Grant – PP160089 Giordano: CDC HIV Prevention – Capacity Building for Routine HIV Testing. Source: U. S. Centers for Disease Control and Prevention, via sub‐contract from Harris Health System Role: Principal investigator of sub‐contract. Dates of Funding: 04/2017‐12/2017 Direct cost: $85,820. Contract – CFDA# 93.940 Giordano: Brief Personalized Feedback Intervention for Hazardous Drinking in an HIV Clinic Source: National Institute on Alcohol Abuse and Alcoholism, NIH. Role: Principal investigator of sub‐contract (Neighbors, University of Houston). Dates of Funding: 02/2017‐01/2020. Direct cost: $95,654 over 3 years. Grant ‐ 1R34 AA023739‐01A1 Mejia: Sponsor: NIH NIAD U01. Term: 7/1/2017 – 6/30/2020. PI: Bethony Co‐I: Mejia. Title: Controlled Infection Trial to Test Efficacy of Hookworm Vaccine with Different

TLR Agonists. Using qPCR to identify those infected with hookworm pre and post vaccination. Mejia: Sponsor: Texas Children’s Hospital Global Health Innovation Grant. Term: 7/1/2017 – 6/30/2018. PI: DiNardo. Co‐I: Mejia. Title: Piloting an innovative, low cost, feasible and highly sensitive stool‐based diagnostic test for children with presumptive pulmonary TB in Mbeya, Tanzania. Using qPCR to associate stool TB DNA diagnostics with pulmonary tuberculosis. Mejia: Roderick Duncan MacDonald Research Fund. Number: 17RDM006. Term: 6/1/2017 – 6/30/2018. PI: Mejia. Title: Prevalence and post‐treatment efficacy for strongyloidiasis in solid organ transplant patients. Determining the prevalence of chronic strongyloidiasis in liver, kidney, and heart transplant patients. Mejia: Sponsor: Thrasher Research Fund. Term: 01/01/2018 – 12/31/2018. PI: McKenna Co‐I and Mentor: Mejia. Title: Hookworm infection in children is associated with negative health outcomes in rural Alabama. Associating hookworm infections with morbidity in children. Mejia: Sponsor: Thrasher Research Fund. Term: 01/01/2018 – 12/31/2018. PI: Nolan Co‐I and Mentor: Mejia. Title: Health Outcomes Evaluation of Children with Gastrointestinal Parasitic and Chagas Disease Co‐Infection” & “Clinical Characterization of Acute Chagas Disease. Immunological polarization with Chagas and intestinal parasite co‐infections. Mejia: Sponsor: Romark Laboratories, LC. Term: 06/01/2018 – 06/01/2019. PI: Mejia Title: Impact of nitazoxanide on Cryptosporidium burden in HIV‐infected patients. Using qPCR to determine impact nitazoxanide has on burden of infection with cryptosporidiosis in HIV‐infected patients. Mejia: Sponsor: NIH Center of Excellence Award. Term: 01/01/2018 – 12/31/2018. PI: Mejia Title: Using Modern Molecular Assays to Determine the Impact of Intestinal Parasites on Different Populations. Using qPCR to associate qPCR of parasites for growth delays in children. Mendoza: Bridge to Independence Funding. Baylor College of Medicine. Mindru: Grant: VA INTREPID. Funding Source: VA Cooperative Study. Grant Title CSP2001 trial Investigation of Rifampin to Reduce Pedal Amputations for Osteomyelitis in Diabetics. Description of project: to assess if addition of rifampin to standard treatment of foot osteomyelitis results in decreased risk of foot amputations. Role: Co‐Investigator Patel: NIH/NIAID VRC 705; 2016‐2020. A Phase 2/2b, Randomized Trial To Evaluate The Safety, Immunogenicity and Efficacy of A Zika Virus DNA Vaccine in Healthy Adults and Adolescents. Patel: HRSA Grant ‐ Ryan White Part F ‐ AETC ; 2015‐2020. Role: Clinical Director of Houston Site AETC – Thomas Street Health Center‐ Harris Health Center. The AIDS Education and Training Centers (AETC) Program of the Ryan White HIV/AIDS Program supports a network of eight regional centers (and more than 130 local affiliated sites) and three national centers that conduct targeted, multidisciplinary education and training programs for health care providers treating people living with HIV. Patel: CDC APHIR‐0006. Munoz (PI). 2014‐2019. Role: Co‐PI (PI of Harris Health component). Pandemic influenza Inpatient Study. This study will report to CDC in real time clinical data in hospitalized pediatric and adult cases of influenza during a pandemic, and evaluate vaccine and antiviral therapies effectiveness. Patel: CDC APHIR‐0006. Munoz (PI). 2015‐2019. Role: Co‐PI (PI of Harris Health component). Pandemic influenza Pregnant Women Study. This study will report to CDC in real time clinical data in hospitalized cases of influenza in pregnant women during a pandemic, and evaluate vaccine and antiviral therapies.

of 17

Patel: CDC APHIR‐0006. Munoz (PI). 2015‐2019. Role: Co‐PI (PI of Harris Health component). Pandemic influenza Ambulatory Study. This study will report to CDC in real time clinical data in ambulatory pediatric and adult cases of influenza during a pandemic, and evaluate vaccine and antiviral therapies effectiveness. Restrepo: Grant Number: Award Number 17RDM006. Sponsor: Roderick D. MacDonald Research Fund Baylor St Luke’s Medical Center. PI: Rojelio Mejia, Alejandro Restrepo, Vagish Hemmige Term: 5.24.2017 – 5.24.2019. STRONGYLOIDES STERCORALIS SURVEILLANCE IN SOLID ORGAN TRANSPLANT RECIPIENTS AND POTENTIAL TRANSPLANT RECIPIENTS LIVING IN THE HOUSTON, TEXAS AREA. Rodrigues‐Barradas: Consortium to improve OutcoMes in HIV/AIDS, Alcohol, Aging, and multi‐Substance use (2/6 COMpAAAS U01) (BCM H‐9976). (PI: Amy Justice, MD, PhD). (NIH AAA, U01AA020790). Contract with Yale University School of Medicine. Role: Houston VA PI. Baylor Proposed Subcontract all 5 years (subject to change): $594,899 Total Costs/$375,330 Direct Costs/up to $49,605 for enrollment. Funding Period: 09/01/2017‐08/31/2021. Current projects under this grant: a. Observation Study: Veterans Aging Cohort Study: Survey and electronic cohort. b. Integrated stepped care for unhealthy alcohol use in HIV. c. Intervention Study: Financial Incentives, Randomization with Stepped Treatment (FIRST) trial (an alcohol treatment study). d. Intervention Study: Medications, Alcohol, Substance use in HIV (MASH) study (a medication reconciliation/polypharmacy study). Rodrigues‐Barradas: An international, multicenter, prospective observational study of the safety of maraviroc used with optimized background therapy in treatment experienced HIV infected patients (BCM H‐23902). Pfizer protocol #A4001067. $14,000 first year, $12,500 subsequent years (based on patient recruitment). 2009‐2014. Rodrigues‐Barradas: NOVVA: 1) Active surveillance to quantify the burden of viral gastroenteritis and acute respiratory infections in US Veterans Affairs (VA) patient population. CDC contract. CDC PI: Cristina Cardemil and Kim Lindsay. Role: MEDVAMC PI. 10/1/2015‐9/30/2018. $452,511.00. Rodrigues‐Barradas: REPRIEVE (A5332): Randomized trial to prevent vascular events in HIV. ACTG/NIH. Role: MEDVAMC PI. 6/1/2015‐5/31/2021. First year: $73,197. Total: $261,468.00. Rodrigues‐Barradas: TRAP‐LRTI (Protocol 15‐0020): Targeted reduction of antibiotics using procalcitonin in a multi‐center randomized, blinded, placebo‐controlled non‐inferiority study of infection (LRTI) and a procalcitonin level of <0.1 ng/ml. 6/2016‐6/2018. Baylor VTEU Protocol. Role: Houston PI. Rodrigues‐Barradas: HIV Tele‐medicine grant: Tele‐health collaborative care grant from the VA Office of Rural Health. In conjunction with Iowa VA, and the Houston, San Antonio, and Dallas VA as participating sites. Houston budget $150,000/year. FY Oct. 1, 2014‐September 30, 2018. Rose: Humanism Rounds: Fighting Physician Burnout Through Strengthened Human Connection (Protocol: H‐42485). Primary Investigator. ACGME Back to Bedside Grant, and Internal Funding, Baylor College of Medicine, January 2018 – present. Serpa: Project: Impact of Parasites on HIV‐infected Immune Recovery (Co‐PI) Sponsor: Baylor‐UT Houston Center for AIDS Research. Trautner: VA Health Services Research & Development IIR (PI Trautner) 10/1/17‐9/30/20

Improving Antibiotic Stewardship for Asymptomatic Bacteriuria VA HSR&D HX002171‐01A1 This project will disseminate the successful Kicking CAUTI intervention to four geographically distinct VA hospitals. Role: PI Trautner: VA HSR&D Career Development Award (PI Skelton) 10/1/17‐9/30/22 Optimizing bacteriuria management in Veterans with spinal cord injury. VA HSR&D HBCU RX002633‐01. This career development award supports Dr. Skelton’s development as an independent clinician‐investigator who studies delivery of optimal care to persons with spinal cord injury. Role: Primary mentor Trautner: AHA Mentored Clinical & Population Research (PI Horstman) 1/2017 – 12/2018 Optimizing Patient‐Initiated Post‐Discharge Care for Patients with Heart Failure. Mentored career development award using mixed methods research to identify patient‐initiated communications strategies for reducing readmissions following CHF discharge. Role: Co‐Mentor Trautner: NIAID R21/R33 5R21AI121545‐02 (PI Ramig) 12/1/15—11/30/18. Bacteriophage to prevent UTI caused by multidrug‐resistant P. aeruginosa This project will develop phage preparations as a means to address MDR P. aeruginosa in the urinary tract. Role: Co‐investigator Trautner: VA IIR 12‐395‐3 (PI Krein) 10/1/14‐3/31/18 VA HSR&D Investigator Initiated Research/Merit Review Identifying and Reducing Catheter‐related Complications. This project explores the infectious and non‐infectious complications of urinary catheters and centrally inserted peripheral catheters. Role: Site PI for Houston Young: Optimal Treatment for Recurrent Clostridium difficile Infection, VA Coop Study #596 (Local PI) 2015‐present

Annual Report Section of

Nephrology

Academic Year 2018

2

Annual Report Section of Nephrology

Grants 13

Editorial Board Memberships/ Editorial Positions

12

Professional Organizations/ Association Offices Held

11

Awards and Honors 10

Publications – Books and Book Chapters

09

Publications - Journals 03

The academic year 2018 has been an exciting one for the Section of Nephrology. Our world-class faculty have made outstanding contributions in research and scholarship, education, and clinical care. They have participated in numerous national and international activities and organizations. And our outpatient practice has moved to our brand-new state-of-the-art facility at the McNair Campus on 7200 Cambridge. This report lists some of the more tangible products delivered and awards and recognitions received during the 12-month period ending in June 2018. In addition, we have continued to provide top quality specialized kidney health care to our patients at our clinical sites within the Texas Medical Center and beyond. Our faculty group practice continues to excel in patient satisfaction and productivity. Please enjoy and thank you for your interest.

Wolfgang C. Winkelmayer, MD, MPH, ScD

Chief, Section of Nephrology Gordon A. Cain Chair in Nephrology

3

Publications Journal Articles

Adrogué HJ, Madias NE. Sodium-chloride difference as a simple parameter for acid-base status assessment. Am J Kidney Dis 2017; 69:708.

Adrogué HJ, Madias NE. Nonosmotic Na+-storage and the Edelman equation. Kidney Int. 2017; 92:514.

Airy M, Chang TI, Ding VY, Goldstein BA, Bansal N, Niu J, Navaneethan SD, Turakhia MP, Winkelmayer WC. Risk profiles for acute health events after incidentatrial fibrillation in patients with end-stage renal disease on hemodialysis. Nephrol Dial Transplant 2017 Nov 13. doi:10.1093/ndt/gfx301. [Epub ahead of print] PubMed PMID: 29145634.

Aymé S, Bockenhauer D, Day S, Devuyst O, Guay-Woodford LM, Ingelfinger JR, Klein JB, Knoers NV, Perrone RD, Roberts J, Schaefer F, Torres VE, Cheung M, Wheeler DC, Winkelmayer WC: Common Elements in Rare Kidney Diseases: Conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference. Kidney Int 2017; 92:796-808.

Baigent C, Herrington WG, Coresh J, Landray MJ, Levin A, Perkovic V, Pfeffer M, Rossing P, Walsh M, Wanner C, Wheeler DC, Winkelmayer WC, McMurray J: Challenges in Conducting Clinical Trials in Nephrology: Report from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference. Kidney Int 2017; 92, 297–305.

Bansal N, Roy J, Chen HY, Deo R, Dobre M, Fischer MJ, Foster E, Go AS, He J, Keane MG, Kusek JW, Mohler E, Navaneethan SD, Rahman M, Hsu CY; CRIC Study Investigators. Evolution of Echocardiographic Measures of Cardiac Disease From CKD to ESRD and Risk of All-Cause Mortality: Findings From the CRIC Study. Am J Kidney Dis 2018 May 18. doi:10.1053/j.ajkd.2018.02.363. [Epub ahead of print].

Brunelli SM, Spiegel DM, Du Mond C, Oestreicher N, Winkelmayer WC, Kovesdy CP: Serum-to-potassium gradient and its association with short-term outcomes in hemodialysis patients. Nephrol Dial Transplant 2017; DOI:10.1093/ndt/gfx241.

Cervantes L, Tuot D, Raghavan R, Linas S, Zoucha J, Sweeney L, Vangala C, Hull M, Camacho M, Keniston A, McCulloch CE, Grubbs V, Kendrick J, Powe NR. Effect of Standard versus Emergency-only Hemodialysis on Mortality and Healthcare Use Among the Undocumented with End-stage Renal Disease: A retrospective cohort analysis. JAMA Intern Med 2018 Feb 1;178(2):188-195. PMID: 29255898

Cervantes L, Richardson S, Raghavan R, Hou N, Hasnain-Wynia R, Kleiner C, Chonchol M, Tong A. Clinicians’ Perspectives on Providing Emergency-Only Hemodialysis to Undocumented Immigrants with End-stage Renal Disease. Ann Intern Med 2018 May 22. PMID: 298000621

Dave NN, Wu J, Thomas SS. Chronic Kidney Disease-Induced Insulin Resistance: Current State of the Field. Curr Diab Rep 2018; 18:44.

Deger SM, Hung AM, Gamboa JL, Siew ED, Ellis CD, Booker C, Feng S, Haiming L, Bian A, Stewart TG, Zent R, Mitch WE, Abumrad NN, Ikizler A. Systemic Inflammation is Associated with Exaggerated Skeletal Muscle Protein Catabolism in Maintenance Hemodialysis Patients. JCI Insight 2017; Nov 16; 2(22): PMID: 29202452.

Dong J, Dong Y, Chen Z, Mitch WE, Zhang L. In CKD, the pathway to muscle fibrosis depends on myostatin stimulating the differentiation of fibro/adipogenic progenitor cells. Kidney Int 91:119-128, 2017. PMID: 27653838. PMCID: PMC5179308

Eckardt KU, Bansal N, Coresh J, Evans M, Grams ME, Herzog CA, James MT, Lambers Heerspink HJ,

4

Pollock CA, Stevens PE, Kurella Tamura M, Tonelli MA, Wheeler DC, Winkelmayer WC, Cheung M, Hemmelgarn BR: Improving the prognosis of patients with severely decreased glomerular filtration rate (CKD G4+): Conclusions from a KDIGO Controversies Conference. Kidney Int 2018; 93:1281-1292.

Eknoyan G. On the contribution of Fernand Widal to the classification of chronic kidney disease. G Ital Nefrol 2018;35(Suppl 70):18-22.

Eknoyan G. A history of uremia research. J Ren Nutrition 2017;27:449-452.

Erickson KE, Zhao B, Ho V, Winkelmayer WC: Employment among Patients Starting Dialysis in the United States. Clin J Am Soc Nephrol 2018; 13:265–273.

Erickson KE, Zheng Y, Ho V, Winkelmayer WC, Bhattacharya J, Chertow GM: Market Competition and Health Outcomes in Hemodialysis. Health Serv Res 2018; DOI: 10.1111/1475-6773.12835.

Erickson KE, Qureshi S, Winkelmayer WC: The Role of Big Data in the Development and Evaluation of U.S. Dialysis Care. Am J Kidney Dis 2018; doi:10.1053/j.ajkd.2018.04.007.

Fischer RSB*, Vangala C*, Truong L, Mandayam S, Chavarria D, Granera Llanes OM, Fonseca Laguna MU, Guerra Baez A, Garcia F, García-Trabanino R, Murray KO. Early detection of acute tubulointerstitial nephritis in the genesis of Mesoamerican nephropathy. Kidney Int 2018; 93:681-690. *contributed equally

Fischer RSB, Mandayam S, Chavarria D, Vangala C, Nolan MS, Garcia LL, Palma L, Garcia F, García-Trabanino R, Murray KO: Clinical Evidence of Acute Mesoamerican Nephropathy. Am J Trop Med Hyg 2017; 97:1247-1256.

Grams ME, Sang Y, Ballew SH, Carrero JJ, Djurdjev O, Heerspink HJL, Ho K, Ito S, Marks A, Naimark D, Nash DM, Navaneethan SD, Sarnak M, Stengel B, Visseren FLJ, Wang AY, Köttgen A, Levey AS, Woodward M, Eckardt KU, Hemmelgarn B, Coresh J. Predicting timing of clinical outcomes in patients with chronic kidney disease and severely decreased glomerular filtration rate. Kidney Int 2018;93:1442-1451.

Guan C, Li Q, Song X, Xu W, Li L, Xu A. Antroquinonol Exerts Immunosuppressive Effect on CD8+ T Cell Proliferation and Activation to Resist Depigmentation Induced by H2O2. Oxid Med Cell Longev 2017;2017:9303054. 2017 Dec 31. PMID:29456788

Jardine MJ, Mahaffey KW, Neal B, Agarwal R, Bakris GL, Brenner BM, Bull S, Cannon CP, Charytan DM, de Zeeuw D, Edwards R, Greene T, Heerspink HJL, Levin A, Pollock C, Wheeler DC, Xie J, Zhang H, Zinman B, Desai M, Perkovic V; CREDENCE study investigators (includes Mandayam S): The Canagliflozin and Renal Endpoints in Diabetes with Established Nephropathy Clinical Evaluation (CREDENCE) Study Rationale, Design, and Baseline Characteristics. Am J Nephrol 2017; 46:462-472.

Kramer J, Puenpatom A, Erickson K, Cao Y, Smith D, El-Serag H, Kanwal F: Real-World Effectiveness of Elbasivir/Grazoprevir in HCV-Infected Patients in the US Veterans Affairs Healthcare System. J Viral Hepat 2018 May 31 [Epub ahead of print]. PMID 29851265.

Ku E, Kopple JD, Johansen KL, McCulloch CE, Go AS, Xie D, Lin F, Hamm LL, He J, Kusek JW, Navaneethan SD, Ricardo AC, Rincon-Choles H, Smogorzewski M, Hsu CY; CRIC Study Investigators. Longitudinal Weight Change During CKD Progression and Its Association With Subsequent Mortality. Am J Kidney Dis 2018;71:657-665.

Kuten SA, Patel SJ, Baru A, Gaber AO, Crutchley RD, Ramanathan V, Knight RJ. Belatacept conversion in an HIV-positive kidney transplant recipient following anti-thymocyte globulin induction. Transpl Infect Dis 2017;19(5) PMID 28708266

Lenihan CR, Liu S, Deswal A, Montez-Rath ME, Winkelmayer WC: De novo heart failure after kidney transplantation: trends in incidence and outcomes. Am J Kidney Dis 2018; DOI: 10.1053/j.ajkd.2018.01.041.

Li J, An C, Kang L, Mitch WE, Wang Y. Recent Advances in Magnetic Resonance Imaging Assessment

https://doi.org/10.1053/j.ajkd.2018.04.007



5

of Renal Fibrosis. Adv Chron Kidney Dis 24:150-153, 2017 PMID 28739140.

Li Q, Lei F, Tang Y, Pan JS, Tong Q, Sun Y, Sheikh-Hamad D: Megalin mediates plasma membrane to mitochondria cross-talk and regulates mitochondrial metabolism. Cell Mol Life Sci 2018 Jun 9. doi: 10.1007/s00018-018-2847-3. [Epub ahead of print] PMID: 29916093

Liang H, Zhang Z, Yan J, Wang Y, Hu Z, Mitch WE, Wang Y. The IL-4 receptor alpha has a critical role in bone marrow-derived fibroblast activation and renal fibrosis. Kidney Int 2017; 92:1433-1443. PMID: 28739140

Liang M, Yu M, Xia R, Song K, Wang J, Luo J, Chen G, Cheng J. Yap/Taz Deletion in Gli+ Cell-Derived Myofibroblasts Attenuates Fibrosis. J Am Soc Nephrol 2017; 28(11):3278-3290.

Luo J, Chen G, Liang L, Xie A, Li Q, Guo Q, Sharma R, Cheng J. Reduced expression of glutathione S transferase alpha 4 promotes vascular neointimal hyperplasia in chronic kidney disease. J Am Soc Nephrol 2018; 29(2):505-517.

Luo J, Feng J, Yu G, Yang P, Mack MR, Du J, Yu W, Qian A, Zhang Y, Liu S, Yin S, Xu A, Cheng J, Liu Q, O'Neil RG, Xia Y, Ma L, Carlton SM, Kim BS, Renner K, Liu Q, Hu H. Transient receptor potential vanilloid 4-expressing macrophages and keratinocytes contribute differentially to allergic and nonallergic chronic itch. J Allergy Clin Immunol 2018 141(2):608-619.

Luo J, Chen G, Liang M, Xie A, Li Q, Guo Q, Sharma R, Cheng J. Reduced Expression of Glutathione S-Transferase α 4 Promotes Vascular Neointimal Hyperplasia in CKD. J Am Soc Nephrol 2017 Nov 10. [Epub ahead of print]. PMID: 29127112.

Mindikoglu AL, Opekun AR, Mitch WE, Magdern LS, Christenson RH, Dowling TC, Weir MR, Seliger SL, Howell CD, Raufman JP, Rana A, Goss JA, Khaderi SA, Vierling JM. Cystatin C is a gender-neutral glomerular filtration rate biomarker in patients with cirrhosis. Dig Dis Sci 2018; 63:665-675. PMID 29392554

Mindikoglu AL, Opekun AR, Putluri N, Devaraj S, Sheikh-Hamad D, Vierling JM, Goss JA, Rana A, Sood GK, Jalal PK, Inker LA, Mohney RP, Tighiouart H, Christenson RH, Dowling TC, Weir MR, Seliger SL, Hutson WR, Howell CD, Raufman JP, Magder LS, Coarfa C: Unique metabolomic signature associated with hepatorenal dysfunction and mortality in cirrhosis. Transl Res. 2018; 195:25-47. PMID: 29291380

Montez-Rath ME, Zheng Y, Kurella Tamura M, Grubbs V, Winkelmayer WC, Chang TI: Hospitalizations and Nursing Facility Stays During the Transition from CKD to ESRD on Dialysis: An Observational Study" in Journal of General Internal Medicine. J Gen Intern Med 2017; DOI: 10.1007/s11606-017-4151-6.

Murray KO, Kolodziej S, Ronca SE, Gorchakov R, Navarro P, Nolan MS, Podoll A, Finkel K, Mandayam S: Visualization of West Nile Virus in Urine Sediment using Electron Microscopy and Immunogold up to Nine Years Postinfection. Am J Trop Med Hyg 2017; 97: 1913-1919.

Navaneethan SD, Mandayam S. Time to Look Beyond Obesity Metrics and Mortality in Kidney Disease. Kidney Int Rep 2017;3:244-246.

Navaneethan SD, Schold JD, Walther CP, Arrigain S, Jolly SE, Virani SS, Winkelmayer WC, Nally JV Jr. High-density lipoprotein cholesterol and causes of death in chronic kidney disease. J Clin Lipidol 2018 Mar 30. pii:S1933-2874(18)30190-9. doi: 10.1016/j.jacl.2018.03.085. [Epub ahead of print]

Navaneethan SD, Virani SS. Omega-3 Fatty Acids (Fish Oil) Supplementation and Albuminuria: Not a Slam Dunk. J Am Heart Assoc 2017; Jul 14;6(7).

Navaneethan SD, Schold JD, Jolly SE, Arrigain S, Blum MF, Winkelmayer WC, Nally JV Jr. Blood pressure parameters are associated with all-cause and cause-specific mortality in chronic kidney disease. Kidney Int 2017; 92:1272-1281.

6

Navaneethan SD, Jolly SE, Schold JD, Arrigain S, Nakhoul G, Konig V, Hyland J, Burrucker YK, Dann PD, Tucky BH, Sharp J, Nally JV. Pragmatic Randomized, Controlled Trial of Patient Navigators and Enhanced Personal Health Records in CKD. Clin J Am Soc Nephrol 2017; 12:1418-1427.

Ning B, Zhao W, Qian C, Liu P, Li Q, Li W, Wang RF. USP26 functions as a negative regulator of cellular reprogramming by stabilizing PRC1 complex components. Nat Commun 2017; 8(1):349.

O’Lone E, Viecelli AK, Craig JC, Tong A, Sautenet B, Roy D, Herrington WG, Herzog CA, Jafar T, Jardine M, Krane V, Levin A, Malyszko J, Rocco MV, Strippoli G, Tonelli M, Wang AYM, Wanner C, Zannad F, Winkelmayer WC, Webster AC, Wheeler DC: Cardiovascular outcomes reported in hemodialysis trials: consistent and important to patients? J Am Coll Cardiol 2018; 71:2102-2810.

Peng H, Wang Q, Lou T, Qin J, Jung SY, Shetty V, Li F, Wang Y, Feng X-H, Mitch WE, Graham B, Hu Z. Myokines mediate muscle-kidney crosstalk suppressing metabolic reprogramming and interstitial fibrosis. Nature Commun 2017; 8:1493-1508. PMID: 29138395.

Perez JJ, Zhao B, Qureshi S, Winkelmayer WC, Erickson KE: Health Insurance and the Use of Peritoneal Dialysis in the United States. Am J Kidney Dis 2017; 71:479-487.

Qureshi S, Erickson KF, Winkelmayer WC: A Case for More Frequent, Not Just Earlier, Nephrology Care of Patients Approaching End-stage Renal Disease? [Editorial] Am J Kidney Dis 2017; 70:155-157.

Qureshi S, Lorch R, Navaneethan SD. Blood Pressure Parameters and their Associations with Death in Patients with Chronic Kidney Disease. Curr Hypertens Rep 2017; 19(11):92.

Raghavan R. Caring for Undocumented Immigrants with Kidney Disease. Am J Kidney Dis 2018; 71:488-494. PMID: 29198642

Raghavan R, Eknoyan G. Uremia: A Historic Reappraisal of What Happened. Clin Nephrol 2018; 89:305-313. PMID: 29451473

Rehman H, Akeroyd JM, Ramsey D, Ahmed ST, Merchant AT, Navaneethan SD, Petersen LA, Virani SS. Facility-level variation in diabetes and blood pressure control in patients with diabetes: Findings from the Veterans Affairs nationa database. Clin Cardiol 2017; 40:1055-1060.

Rincon-Choles H, Jolly SE, Arrigain S, Konig V, Schold JD, Nakhoul G, Navaneethan SD, Nally JV Jr, Rothberg MB. Impact of Uric Acid Levels on Kidney Disease Progression. Am J Nephrol 2017;46:315-322.

Sautenet B, Tong A, Williams G, Hemmelgarn BR, Manns B, Wheeler DC, Tugwell P, van Biesen W, Winkelmayer WC, Crowe S, Harris T, Evangelidis N, Hawley CM, Pollock C, Johnson DW, Polkinghorne KR, Howard K, Gallagher MP, Kerr PG, McDonald SP, Ju A, Craig JC: Scope and consistency of outcomes reported in randomized trials conducted in adults receiving hemodialysis: a systematic review. Am J Kidney Dis 2018; DOI: 10.1053/j.ajkd.2017.11.010.

Sautenet B, Tong A, Manera KE, Chapman JR, Warrens AN, Rosenbloom D, Wong G, Gill J, Budde K, Rostaing L, Marson L, Josephson MA, Reese PP, Pruett TL, Hanson CS, O'Donoghue D, Tam-Tham H, Halimi JM, Shen JI, Kanellis J, Scandling JD, Howard K, Howell M, Cross N, Evangelidis N, Masson P, Oberbauer R, Fung S, Jesudason S, Knight S, Mandayam S, McDonald SP, Chadban S, Rajan T, Craig JC. Developing Consensus-Based Priority Outcome Domains for Trials in Kidney Transplantation: A Multinational Delphi Survey With Patients, Caregivers, and Health Professionals. Transplantation. 2017; 101:1875-1886.

Shah MK, Mandayam S, Adrogué HJ. Osmotic Demyelination Unrelated to Hyponatremia. Am J Kidney Dis 2018; 71:436-440. PMID: 29277507

Shen JI, Dave NN, Erickson KF: Home Alone: Does Modality Matter? Revisiting Hospital Readmissions in Dialysis. Am J Kidney Dis 2017; 70;1-3.



7

Snitker S, Doerfler RM, Soliman EZ, Deo R, St Peter WL, Kramlik S, Fischer MJ, Navaneethan S, Delafontaine P, Jaar BG, Ojo A, Makos GK, Slaven A, Weir MR, Zhan M, Fink JC; for CRIC Study Investigators. Association of QT-Prolonging Medication Use in CKD with Electrocardiographic Manifestations. Clin J Am Soc Nephrol 2017 Aug 9. pii: CJN.12991216. doi: 10.2215/CJN.12991216. [Epub ahead of print]

Swanepoel CR, Atta MG, D’Agati VD, Estrella MM, Fogo AB, Naicker S, Post FA, Wearne N, Winkler CA, Cheung M, Wheeler DC, Winkelmayer WC, Wyatt CM: Kidney Disease in the Setting of HIV Infection: Conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference. Kidney Int 2018; DOI: 10.1016/j.kint.2017.11.007.

Thomas SS, Mitch WE. Parathyroid hormone stimulates adipose tissue browning: a pathway to muscle wasting. Curr Opin Clin Nutr Metab Care 2017; 20:153-157.

Tong A, Crowe S, Gill J, Harris T, Hemmelgarn B, Manns B, Pecoits-Filho R, Tugwell P, van Biesen W, Wang A, Wheeler DC, Winkelmayer WC, Gutman T, Ju A, O’Lone E, Sautenet B, Viecelli A, Craig JC: Clinicians’ and researchers’ perspectives on establishing and implementing core outcomes in haemodialysis: semistructure interview study. BMC Nephrol 2018; 8:e021198.

Torres VE, Chapman AB, Devuyst O, Gansevoort RT, Perrone RD, Koch G, Ouyang J, McQuade RD, Blais JD, Czerwiec FS, Sergeyeva O; REPRISE Trial Investigators (includes Mandayam S). Tolvaptan in Later-Stage Autosomal Dominant Polycystic Kidney Disease. N Engl J Med 2017; 377:1930-1942.

Turakhia MP, Blankestijn PJ, Carrero JJ, Clase CM, Deo R, Herzog CA, Kasner SE, Passman RS, Pecoits-Filho R, Reinecke H, Shroff GR, Zareba W, Cheung M, Wheeler DC, Winkelmayer WC, Wanner C: Chronic Kidney Disease and Arrhythmias: Conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference. Eur Heart J DOI:10.1093/eurheartj/ehy060.

Venkatasubba Rao CP, Bershad EM, Calvillo E, Maldonado N, Damani R, Mandayam S, Suarez JI: Real-time Noninvasive Monitoring of Intracranial Fluid Shifts During Dialysis Using Volumetric Integral Phase-Shift Spectroscopy (VIPS): A Proof-of-Concept Study. Neurocrit Care. 2018; 28:117-126.

Walther CP, Shah AA, Winkelmayer WC: Treating Depression in Patients with Advanced Kidney Disease: Beyond the Generalizability Frontier. [Editorial] J Am Med Assoc 2017; 318:1873-1875.

Walther CP, Winkelmayer WC, Deswal A, Niu J, Navaneethan SD. Trends in Left Ventricular Assist Device Implantation and Associated Mortality Among Patients With and Without ESRD. Am J Kidney Dis 2018 May 18. doi: 10.1053/j.ajkd.2018.03.020. [Epub ahead of print].

Walther CP, Chandra A, Navaneethan SD. Blood pressure parameters and morbid and mortal outcomes in nondialysis-dependent chronic kidney disease. Curr Opin Nephrol Hypertens 2018; 27:16-22.

Walther CP, Whaley-Connell A, Navaneethan SD. Emerging therapeutic options for managing diabetic kidney disease. Curr Opin Nephrol Hypertens 2017; 26:335-337.

Walther CP, Gutierrez OM, Cushman M, Judd SE, Lang J, McClellan W, Muntner P, Sarnak MJ, Shlipak MG, Warnock DG, Katz R, Ix JH. Serum albumin concentration and risk of end-stage renal disease: The REGARDS Study. Nephrol Dial Transplant [Epub ahead of print Dec 20 2017].

Walther CP, Shah AA, Winkelmayer WC. Treating depression in patients with advanced CKD: Beyond the generalizability frontier J Am Med Assoc 2017; 318:1873-1874.

Wang Y, Jia L, Hu Z, Entman ML, Mitch WE, Wang Y. AMP-activated protein kinase/myocardin-related transcription factor-A signaling regulates fibroblast activation and renal fibrosis. Kidney Int 2018; 93:81-94. PMID: 28739141

Woodard LE, Welch RC, Williams FM, Luo W, Cheng J, Wilson MH. Hydrodynamic renal pelvis injection for Non-viral expression of proteins in the kidney. J Vis Exp 2018; 8;(131)

8

Woodard LE, Cheng J, Welch RC, William FM, Luo W, Gewin LS, Wilson MH. Kidney-specific transposon-mediated gene transfer in vivo. Sci Rep 2017; 7:44904.

Yuan CM, Nee R, Little DJ, Narayan R, Childs JM, Prince LK, Raghavan R, Oliver JD. Survey of Kidney Biopsy Clinical Practice and Training in the United States. Clin J Am Soc Nephrol. 2018 May 7;13(5):718-72. Accompanying visual abstract created by Raghavan R. PMID: 29669819

Zhan M, St. Peter W, Doerfler RM, Woods CM, Blumenthal JB, Diamantidis, CJ, Hsu CY, Lash JP, Lustigova E, Mahone EB, Ojo AO, Slaven A, Strauss L, Taliercio JJ, Winkelmayer WC, Xie D, Fink JC, and the Chronic Renal Insufficiency Cohort (CRIC) Study investigators: Patterns of Non-steroidal Anti-inflammatory Drugs Use and Their Impact on Other Analgesic Use in Chronic Kidney Disease. Clin J Am Soc Nephrol 2017; 12:1778-1786.

Zhao W, Tan P, Zhu Q, Ajibade A, Long T, Long W, Li Q, Liu P, Ning B, Wang HY, Wang RF. Tgfbr2 inactivation facilitates cellular plasticity and development of Pten-null prostate cancer. J Mol Cell Biol 2017 Dec 8. PMID: 29228234

Zhou J, Jia L, Hu Z, Wang Y. Pharmacological inhibition of PTEN aggravates acute kidney injury. Sci Rep 2017; 7:9503. PMCID: PMC5572703



9

Publications Books and book chapters

Knights S and Raghavan R. HIV Associated Kidney Disease; in Update on the Care of HIV Positive Patients (2017). Editor: Wayne Shandera. ISBN: 978-1-53613-065-2

Madias NE and Adrogué HJ. Respiratory acid-base disorders. Chapter in Seldin and Giebisch’s The Kidney: Physiology and Pathophysiology, 6th Edition, edited by Alpern R, Caplan M, Moe O, Quaggin S. Elsevier/Academic Press

Handbook of Nutrition and the Kidney 7th Edition, T. A. Ikizler and W. E. Mitch, Editors, Wolters Kluwer, Philadelphia, 2018

Perez JJ and Mitch WE. Requirements for protein, calories and fat in the predialysis patient. Handbook of Nutrition and the Kidney, 7th Edition, T. Alp Ikizler and William E. Mitch, Editors, Wolters Kluwer, Philadelphia, 2018, pp 77-90.

Qureshi SJ, Awan AA, Adrogué HJ. Hyponatremia. In: Fadem S (ed.) Essentials of Chronic Kidney Disease. Second Edition. Nova Science, 2018.

Yan J and Mitch WE. Nutritional therapy for patients with chronic kidney diseases, Essentials of chronic kidney disease, 2nd Edition, S. Z. Fadem, Editor, NOVA Science Publishers, Hauppauge, New York, 2018

10

Awards and Honors

Section FGP Faculty and Staff: “That’s The Way 10k Award” Nephrology section award for most improvement in patient satisfaction (July 2017 to June 2018)

Section FGP Faculty and Staff: Highest Ranking in Patient Experience – All-Star Winner for FY18 Quarter 3

Adrogue: Senior Faculty Teaching Award, Section of Nephrology, Baylor College of Medicine, June 2018

Murthy: “Unsung Hero” Fellowship Award, Section of Nephrology, Baylor College of Medicine, June 2018

Perez: Invited Delegate, KDIGO Controversies Conference on Dialysis Initiation, Madrid, Spain, January 2018

Raghavan: PEEPSS – Inaugural member, Team Leader, BCM Center for Professionalism (February to September 2018)

Saridey: Norton Rose Fulbright Faculty Excellence Award for Teaching and Evaluation, Baylor College of Medicine, May 2018

Saridey: Star Award for Excellence in Patient Care, Baylor College of Medicine, May 2018

Thomas: Best Research Poster Award, American College of Cardiology, 2018.

Yan: Junior Faculty Teaching Award, Section of Nephrology, Baylor College of Medicine, June 2018.

11

Professional Organization/Association Offices Held

Erickson: Member, Quality, Patient Safety, and Clinical Practice Committee, American Society of Nephrology, Washington, D.C.

Erickson: Member, PTAC Joint Working Group, American Society of Nephrology, Washington, D.C.

Winkelmayer: Member, Quality, Patient Safety, and Clinical Practice Committee, American Society of Nephrology, Washington, D.C.

Winkelmayer: Co-Chair, Kidney Disease: Improving Global Outcomes (KDIGO), Brussels, Belgium.

Winkelmayer: Member, Advisory Board, Chronic Kidney Disease Surveillance System, Center for Disease Control, Atlanta, GA.

Winkelmayer: Member, External Expert Panel, United States Renal Data System, National Institutes of Diabetes and Digestive and Kidney Diseases, Bethesda, MD.

Zhang: American Diabetes Association: Member, Research Grant Review Committee, Arlington, VA.

12

Editorial Board Memberships and Editorial Positions

Erickson: Editorial Board, American Journal of Kidney Diseases

Erickson: Public Policy Forum Steering Committee, American Journal of Kidney Diseases

Erickson: Guest Editor, Special Issue on Health Policy, Seminars in Dialysis

Mitch: Editorial Board, Kidney International

Mitch: International Advisory Board, Clinical and Experimental Nephrology

Mitch: Editorial Board. Journal of the American Society of Nephrology

Navaneethan: Associate Editor, American Journal of Kidney Diseases

Navaneethan: Associate Editor, NephSAP (Nephrology - Self Assessment Program)

Navaneethan: Associate Editor, CardioRenal Medicine

Navaneethan: Editorial Board, Clinical Journal of American Society of Nephrology

Navaneethan: Editorial Board, American Journal of Nephrology

Pan: Editorial Board, American Journal of Physiology-Renal Physiology

Sheikh-Hamad: Editorial Board, American Journal of Physiology-Renal Physiology

Wang: Editorial Board, Scientific Reports

Wang: Editorial Board, Journal of Nephrology and Therapeutics

Wang: Editorial Board, Science Postprint

Wang: Editorial Board, International Journal of Transplantation Research and Medicine

Wang: Editorial Board, Journal of Nephrology Research

Winkelmayer: Associate Editor, Journal of the American Medical Association

Winkelmayer: Editorial Board, American Journal of Kidney Diseases

Winkelmayer: Public Policy Forum Steering Committee, American Journal of Kidney Diseases

Winkelmayer: Editorial Board, American Journal of Nephrology

Winkelmayer: Editorial Board, Clinical Journal of American Society of Nephrology

Winkelmayer: Editorial Board, Seminars in Dialysis

Winkelmayer: Guest Editor, Special Issue on Health Policy, Seminars in Dialysis

Winkelmayer: Editorial Board, Clinical Journal of American Society of Nephrology

Zhang: Editorial Board, Austin Diabetes Research

Zhang: Editorial Board, Journal of Nephrology & Therapeutics

13

Grants

Cheng (PI): Chronic kidney disease adversely influences vascular functions. NIH/NIDDK; R01 DK095867; 3/15/2013–1/31/2019.

Cheng (PI): Epigenetic alterations of GSTA4 regulate CKD-induced vascular remodeling American Heart Association; 7/1/2015–6/30/2018.

Erickson (PI): The Effect of Provider Market Competition of Health Outcomes in Dialysis. NIH/NIDDK, K23 DK101693; 4/1/2014-1/31/2019.

Erickson (PI): Dialysis Facility Closures and their Effect on Costs, Health Outcomes, and Access to Care. Carl W. Gottschalk Research Scholar Grant, American Society of Nephrology; 7/1/2017-6/30/2019.

Erickson (PI): Nephrology Care and Employment after Starting Dialysis. National Kidney Foundation Research Grant Program – Southeast Texas Research Grant, National Kidney Foundation; 7/1/2017-6/30/2019.

Erickson (Co-I; PI: Kanwal, BCM): Real-world Effectiveness and Impact of Elbasivir/Grazoprevir on Outcomes among HIV-Infected Patients. Merck & Co., Inc.; 9/1/2016-12/31/2017.

Erickson (PI): Junior Faculty Seed Funding Award; Baylor College of Medicine; 6/15/2018-6/30-2019.

Hu (PI): Mechanisms of Protein-Energy-Wasting in Chronic Kidney Disease. NIH/NIAMS, R01 DK063868; 7/1/2013-4/30/2019.

Klotman (PI): Long-term Consequences of HIV in the Kidney. NIH/NIDDK, P01 DK056402; 9/15/1999-4/30/2022.

Mandayam (PI): Effect of Oral Ferric Citrate on ESA use in ESRD patients on Hemodialysis with high ferritin and low transferrin saturation. A pilot pragmatic clinic trial. Keryx Biopharmaceuticals. 8/1/2017-7/31/2019.

Mitch (PI): Protein nutrition in experimental uremia. NIH/NIDDK, R01/R37 DK037175; 9/1/1987-3/31/2022.

Navaneethan (PI): Visceral adiposity and physical function in CKD. NIH/NIDDK R01 DK101500; 9/22/2015- 7/31/2019.

Navaneethan (PI): Prevalence, management and outcomes of iron deficiency anemia in CKD. Keryx Biopharmaceuticals; 1/12/2018- 12/31/2019.

Pan (PI): Stanniocalcin-1, Kidney Protection by AMPK. VA/CDA, IK2 BX002912; 1/1/2017-12/31/2021.

Raghavan (PI): Difficult Conversations in Nephrology: Communications Workshop; BCM Education Grant; 7/2017-6/2018.

Sheikh-Hamad (PI): Stanniocalcin-1, New Paradigms for Cytoprotection and Antiinflammation. VA/Merit, I01 BX002006; 4/1/2014-3/31/2018.

Thomas (PI): Chronic Kidney Disease and Impaired Actions of Insulin. VA/CDA, IK2 BX002492; 4/1/2015-3/31/2020.

Wang (PI): Cellular and Molecular Mechanisms of Renal Fibrosis. NIH/NIDDK, R01 DK095835; 9/3/2012-4/30/2022.

14

Wang (PI): NovelMechanisms of Hypertensive Kidney Injury and Fibrosis. VA/Merit, I01 BX002650; 10/1/2015-9/30/2019.

Winkelmayer (PI): The Atrial Fibrillation – Factor Identification to Risk Modification Study in HD (AFFIRM-HD). NIH/NIDDK, R01 DK095024; 8/1/2012-5/31/2019.

Winkelmayer (Co-I and Site-PI): Pragmatic Trials in Hemodialysis. NIH/NIDDK; UH2/UH3 DK102384; 9/30/2012-8/31/2018.

Winkelmayer (Co-I and Site-PI): Establishing Core Outcomes in Haemodialysis. NHMRC (National Health and Medical Research Council of Australia); APP1098815; 1/1/2016-12/31/2018.

Zhang (Co-PI): Protein nutrition in experimental uremia. NIH/NIDDK, R01/R37 DK037175; 9/1/1987-3/31/2022.

Pulmonary, Critical Care and Sleep Medicine

Section Summary Report July 2018

Rolando E. Rumbaut, MD, PhD Interim Section Chief, Pulmonary, Critical Care and Sleep Medicine

Professor of Medicine and Pediatrics Baylor College of Medicine &

Deputy Associate Chief of Staff for Research Director, Center for Translational Research on Inflammatory Diseases (CTRID)

Michael E. DeBakey VA Medical Center

Outline:

1. Overview 2. Faculty 3. Clinical Services:

Ben Taub General Hospital (BTGH) Michael E. DeBakey VA Medical Center (MEDVAMC) Baylor Faculty Group Practice Baylor St. Luke’s Medical Center (BSLMC) Pavilion for Women (PFW)

4. Education 5. Research 6. Publications 7. 2017-2018 Fellowship Graduates

1. Overview The Pulmonary, Critical Care, and Sleep Medicine Section in the Department of Medicine oversees the clinical, education, and research activities in these three related disciplines at Baylor College of Medicine and its affiliated hospitals. Its 44 full-time faculty members direct these activities at Ben Taub Hospital/Harris County Hospital District, the Michael E. DeBakey VA Medical Center (MEDVAMC), the Baylor Faculty Group Practice, Baylor St. Luke’s Medical Center (BSLMC), and the Pavilion for Women (PFW) at Texas Children’s Hospital.

2. Faculty

(link to faculty website)

https://www.bcm.edu/departments/medicine/sections-divisions-centers/pulmonary-critical-care-sleep-medicine/faculty

NON-CLINICIAN RESEARCH FACULTY Name Rank Primary research area Aladin Boriek PhD Professor Mechanical signal

transduction Mustafa Atik MD Instructor Airway diseases Monica Jeongsoo Hong PhD Instructor Lung immunity

CLINICIAN FACULTY

(Listed based on primary site of practice) Name Rank Primary track/area of activity

Ben Taub General Hospital

Kalpalatha Guntupalli MD Professor and Service Chief at Ben Taub

Pulmonary, Critical Care Sleep

Philip Alapat MD Assistant Professor Pulmonary, Critical Care Sleep

Nicola Hanania MD Associate Professor Pulmonary, Critical Care Asthma/COPD

Elizabeth Guy MD Assistant Professor Pulmonary, Critical Care Sleep and Tuberculosis

Resmi George NP (Nurse Practitioner)

Clinical instructor Pulmonary

Dharani Narendra MD Assistant Professor Pulmonary, Critical Care and

Ob Critical Care Purvesh Patel MD Assistant Professor

Pulmonary, Critical Care Ultrasound/ECHO ILD

Pralay Sarkar MD Assistant Professor Pulmonary, Critical Care Ultrasound/ECHO

Michael E DeBakey VA Medical Center Venkata Bandi MD Professor and Service Chief Pulmonary, Critical Care

Sleep and Interventional Charlie Lan MD Associate Professor

Associate Chief of Medical Care Line, MEDVAMC


Ray Lazarus MD Assistant Professor Pulmonary, Critical Care Interventional, Director of Interventional Pulmonary

Steve Bujarski MD Assistant Professor Pulmonary, Critical Care Farrah Kheradmand MD Professor Pulmonary, Critical care

COPD and Lung Cancer research

Lavannya Pandit MD Assistant Professor Pulmonary, Critical Care Pulmonary Hypertension

Rolando Rumbaut MD PhD Professor Director, Center for Translational Research on Inflammatory Diseases & Deputy Associate Chief of Staff for Research, MEDVAMC

Pulmonary, Critical Care Microvascular research

Amir Sharafkhaneh MD PhD Professor Pulmonary, Critical Care Sleep

Supriya Singh MD Assistant Professor Pulmonary, Critical care Sleep

Kanta Velamuri MD Associate Professor Pulmonary, Critical Care Sleep

Uma Ayyala MD Assistant Professor Associate Chief of Staff for Education, MEDVAMC

Pulmonary, Critical Care

Shahram Moghtader MD BCM faculty title in process Pulmonary, Critical Care Sleep

Ritwik Agrawal MD Assistant Professor Pulmonary, Critical Care Sleep

BCM Faculty Group Practice Fidaa Shaib MD Associate Professor

Director of the Pulmonary FGP & Director of BSLMC Sleep Center


Prasad Manian MD

Professor, Associate Section Chief for Clinical Affairs, Director of the Department of Medicine FGP


Ali Jiwani MD Assistant Professor Pulmonary, Critical Care Interventional Pulmonology

Gloria Li MD (*also Lung Transplant)

Assistant Professor Pulmonary, Critical Care Lung Transplant

Jigna Zatakia DO (*also BSLMC MICU)

Assistant Professor Pulmonary, Critical Care ILD

Dipa Modi MD (*also BSLMC MICU)

Assistant Professor Pulmonary, Critical Care Pulmonary Rehabilitation

Thomas Monaco MD (*as of Sept 2018, also BSLMC MICU)

Assistant Professor Pulmonary, Critical Care

N. Tony Eissa MD (*anticipated future part-time FGP practice)

Professor, Associate Section Chief for Research

Pulmonary, Critical Care Immunity & autophagy research

Annise Wilson, MD (*as start August 2018)

Assistant Professor of Neurology, 2yr appointment in Medicine

Sleep Medicine

Cystic Fibrosis Tara Barto MD Assistant Professor

Interim Director of Cystic Fibrosis Center

Pulmonary, Critical Care Cystic Fibrosis

Lung Transplant Amit Parulekar MD Associate Professor

Medical Director of Lung Transplant Program

Pulmonary, Critical Care Transplant

Goutham Dronavalli MD Assistant Professor Pulmonary, Critical Care Transplant

Christina Kao MD Assistant Professor Pulmonary, Critical Care Transplant

Baylor St. Luke’s Medical Center MICU James Herlihy MD Professor

Chief of Critical Care service line, BSLMC


Muhammad Asim Siddique MD Assistant Professor ICU, Director of MICU


Jairo Barrantes – Perez MD Assistant Professor Pulmonary, Critical Care Sleep

Christopher Howard MD Assistant Professor ICU


Christopher Morgan MD Assistant Professor ICU


DeReddi Reddy MD Assistant Professor

Internal Medicine, Critical Care

Babith Mankidy MD Assistant Professor ICU

Pulmonary, Critical Care Sleep, Transplant

Andrea Braun MD Assistant Professor ICU

Internal Medicine, Nephrology, Critical Care

Ali Omranian MD Assistant Professor Internal Medicine Critical Care

Pavilion for Women David Muigai MD

Assistant Professor Internal Medicine, Critical Care; Medical Director of Critical Care Service

3. Clinical Services 3a Ben Taub General Hospital: Services Provided: Pulmonary Critical Care Sleep Critical Care ECHO/Ultrasound service Interventional Pulmonary services Procedures Service to the Internal Medicine service Tuberculosis care to the region Ambulatory care 3b Michael E DeBakey VA Medical Center: Services provided: Pulmonary Consultations Critical Care Sleep Interventional Pulmonary services Pulmonary Hypertension

Home Oxygen Program Step Down Unit 3c Baylor Faculty Group Practice and Baylor St. Luke’s Medical Center Pulmonary & Sleep Services Inpatient and outpatient General Pulmonary Cystic fibrosis Interventional pulmonary services Lung transplantation Sleep medicine Interstitial lung disease Pulmonary hypertension (service in development)

3d St. Luke’s Medical Center Critical Care Services Medical Intensive Care Unit Mobile intensive Care Unit Coronary Care Unit Cardiovascular Intensive Care Unit 3e Pavilion for Women Obstetrics/Critical Care Unit Pulmonary Consultation

4. Education 4a Pulmonary and Critical Care Fellowship (3-year combined program): ACGME approved

Program Director: Amit Parulekar, MD Associate Program Directors: Uma Ayyala MD, Stephen Bujarski MD, Christina Kao MD,

Pralay Sarkar MD

Current fellows (2018-2019)

Name Medical School Residency Sara Assaf, MD American University of Beirut

Faculty of Medicine Saint Louis University

Ali Cheema, MD University of Oklahoma College of Medicine


Jose Cuevas, MD Unverisdad Autonoma, Mexico

Texas Tech Health Science Center

Sunjay Devarajan, MD Texas A&M Health Science Center College of Medicine

Georgetown University Hospital

Adriel Fajilan, MD Loma Linda University School of Medicine

Harbor UCLA Medical Center

Amy Heibel, MD Texas A&M Health Science Center

Ochsner Clinic Foundation

Megan Hughes, MD University of Texas School of Medicine at San Antonio

LSU Health Science Center Shreveport

Katie Jeans, MD Louisiana State University School of Medicine in New Orleans


Gilboa Lombardi, MD Technischen Universität München Fakultät für Medizin

Vanderbilt University

Ninad Maniar, MD Seth G.S. Medical College University of Louisville Robbie Maxson, MD Eastern Virginia Medical

School Temple University Hospital

Katie Moeller, DO Lake Erie College of Osteopathic Medicine

Drexel University of College of Medicine

Todd Schlossman, MD American University of the Caribbean

West Virginia University

Justin Segraves, MD New York Medical College Mayo Clinic Omar Shweish MD Istanbul University St. Elizabeth’s Medical Center

4b Critical Care Fellowship (1-2 years): ACGME approved

Program Director: Kalpalatha Guntupalli MD Associate Program Directors: Raja Reddy, MD, Andrea Braun, MD


Name Medical School Residency Badr Alsaleh, MD King Abdulaziz University,

SAU Ochsner Clinic Foundation

Bria Giacomino, DO Arizona College of Osteopathic Medicine of Midwestern University

University of Iowa

Megan Gooch, MD Commonwealth Medical College

Cooper University Hospital

Goutham Gudavalli, MD Kakatiya Medical College LSU Health Science Center Lafayette

Simran Matta, MD Maharashtra Inst. of Medical Education & Research (MIMER)

University of Nevada

Sri Kartik Valluri, MD Bhaskar Medical College University of Miami

4c Sleep Fellowship: ACGME approved Program Director: Phil Alapat MD Associate Program Director: Supriya Singh, MD


Name Medical School Residency Myrtle Jeroudi MD UT Southwestern UT Southwestern Skantha Manjunath MD Osmania Medical College University of Tennessee Jen Molina MD University of Santo Thomas University of Illinois College

of Medicine Jose Moonjely MD St. John’s Medical College Western Reserve Health

4d National Institutes of Health T-32 Training Grant on Lung Diseases:

Program Director: Tony Eissa, MD Positions: 4 Status: Active (no section clinical fellows currently enrolled)

4e Transplant Fellowship: (Texas Board Approved)

Director: Amit Parulekar, MD Positions: 1-2 Status: INACTIVE

4f Interventional Pulmonary Fellowship (Texas Board Approved)

Director (anticipated): D. Ray Lazarus, MD Position: 1

Status: INACTIVE, PENDING INITIATION Weekly Fellowship Noon Conferences

Tuesday Wednesday Friday Core curriculum, journal club

Research conference; St. Luke’s Pulmonary Grand Rounds;

X Ray Case conference; Quality improvement conference

Critical Care case conference

Site-specific conferences (not mentioned above)

BTGH MEDVAMC BSLMC / FGP PFW

Tumor Board CC Board review CC Journal club

Tumor Board; Weekly Case Conference

Patient-Centered Clinical Research;

CTRID seminar series

Tumor Board (BSLMC)

Sleep Medicine Board Review (FGP)

ICU topic review; Multidisciplinary case

conference

5. Research

5a. Grants and Contracts Awarded: 07/01/2017 - 06/30/2018 MEDICINE: PULMONARY

Principal Investigator

Sponsor

Grant Number

Project Title Budget Period DIRECT INDIRECT Total

KHERADMAND,FARRAH (MPI)

NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES (NIAID)

1R01AI135803-01

FUNGAL PATHOGENESIS OF MODERATE TO SEVERE ASTHMA

03/23/18-02/28/23 $357,458 $198,494 $555,952

KHERADMAND,FARRAH

MICHAEL E DEBAKEY VA MEDICAL CENTER

2I01CX000104-09

INNATE AND ACQUIRED IMMUNE RESPONSES IN HUMAN COPD

07/1/17-6/30/18 $150,000 $0 $150,000

NIH Other Federal Non-Federal Cash Total

MEDICINE: PULMONARY $523,567.00 $365,350.00 $271,078.00 $270,099.90 $1,430,094.90

TOTALS $523,567.00 $365,350.00 $271,078.00 $270,099.90 $1,430,094.90

RUMBAUT, ROLANDO

MICHAEL E DEBAKEY VA MEDICAL CENTER

5I01BX002551-03

PLATELETS AND MICROVASCULAR THROMBOSIS IN INFLAMMATION

04/01/18-03/31/19 $150,000 $0 $150,000

EISSA, TONY ALPHA ONE FOUNDATION 501272 LYSOSOMAL ORIGIN

FOR EMPHYSEMA 7/1/17 - 6/30/18 $100,000 $0.00 $100,000

PARULEKAR, AMIT D.

AMERICAN LUNG ASSOCIATION

CG-415676 - Year 2

YR 2: THE IMPACT OF FUNGAL SENSITIZATION AND AIRWAY FUNGAL MICROBIOME ON ASTHMA SEVERITY

7/1/17 - 6/30/18 $40,000.00 $0.00 $40,000

HANANIA, NICOLA ALEXANDER

AMERICAN LUNG ASSOCIATION Year 2

AIRWAYS CLINICAL RESEARCH CENTERS (ACRC)

7/1/17 - 6/30/18 $100,000 $0.00 $100,000

KHERADMAND,FARRAH

DEPARTMENT OF DEFENSE CONGRESSIONALLY DIRECTED MEDICAL RESEARCH PROGRAMS

W81XWH-16-1-0361 YR 2

YR 1: PR140593P1: ENHANCEMENT OF IMMUNE MEMORY RESPONSES TO RESPIRATORY INFECTION

8/1/17 - 7/31/18 $231,944 $133,406 $365,350

EISSA, TONY

NATIONAL HEART, LUNG, AND BLOOD INSTITUTE (NHLBI)

T32-HL007747-22

YR 22: RESEARCH TRAINING IN LUNG DISEASE

7/1/17 - 6/30/18 $421,890 $27,351 $449,241

BORIEK, ALADIN M


R25-HL108853-07

YEAR 7 - RPPR (MPI) : SHORT TERM TRAINING TO INCREASE DIVERSITY

4/1/2018 - 3/31/2019

$68,820 $5,506 $74,326

RUMBAUT, ROLANDO


R01-HL116524-05 NCE

(MPI): NCE PLATELETS AND THEIR MICROPARTICLES IN THE INFLAMED MICROCIRCULATION

2/1/2018 - 1/31/2019

$0.00 $0.00 $0.00


THE CHEST FOUNDATION

DS RH 2013 YR 3 NCE

NCE TO 6/30/2018 “SPIROMETRY TOOLKIT” TO IMPROVE KNOWLEDGE AND APPROPRIATE USE OF SPIROMETRY IN THE PRIMARY CARE SETTING

4/1/2018 - 6/30/2018

$0.00 $0.00 $0.00

Cash Awards

Principal Investigator

Sponsor Project Title Fiscal Year Direct Indirect Total


AMERICAN LUNG ASSOCIATION

“LOSARTAN EFFECTS ON EMPHYSEMA PROGRESSION TRIAL” (LEEP) TRIAL

2018 $2,165 $0.00 $2,165

GUNTUPALLI, KALPALATHA K

BOEHRINGER INGELHEIM LTD

IDIOPATHIC PULMONARY FIBROSIS PROSPECTIVE OUTCOMES REGISTRY (IPF-PRO)

2018 $2,500 $0.00 $2,500


BOEHRINGER INGELHEIM PHARMACEUTICAL, INC

OBSERVATIONAL STUDY IN HEALTHY SUBJECTS AND PATIENTS WITH COPD TO ASSESS THE RELATIONSHIP BETWEEN CLINICAL, IMAGING AND BIOMARKER MEASUREMENTS, AND PROGRESSION OF EMPHYSEMA OVER TWO YEARS.

2018 $41,012.26 $10,632.81 $51,645.07

BARTO, TARA LYNN

CORBUS PHARMACEUTICALS

JBT101-CF-001: A PHASE 2, DOUBLE-BLIND, RANDOMIZED, PLACEBO-CONTROLLED MULTICENTER STUDY TO EVALUATE SAFETY, TOLERABILITY, EFFICACY, AND PHARMACOKINETICS OF JBT-101 IN CYSTIC FIBROSIS

2018 $1,385.08 $178.70 $1,563.78


F. HOFFMANN-LA ROCHE LTD

A PHASE II, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED STUDY TO ASSESS THE EFFICACY AND SAFETY OF LEBRIKIZUMAB IN PATIENTS WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE AND A HISTORY OF EXACERBATIONS

2018 $4,566.90 $627.86 $5,194.76


GENENTECH, INC.

A PROSPECTIVE, SINGLE ARM, LONGITUDINAL COHORT STUDY TO ASSESS BIOMARKERS IN REAL WORLD PATIENTS WITH SEVERE ASTHMA

2018 $17,703.90 $4,589.90 $22,293.80


GLAXO/SMITHKLINE

A RANDOMIZED, DOUBLE-BLIND, SPONSOR OPEN, PLACEBO-CONTROLLED, 52 WEEK STUDY EVALUATION THE EFFECT OF DANIRIXIN (GSK1325756) ON LUNG FUNCTION AND HEALTH RELATED QUALITY OF LIFE IN PARTICIPANTS WITH MILD TO MODERATE CHRONIC OBSTRUCTIVE PULMONARY DISEASE (COPD)

2018 $11,402.07 $2,956.10 $14,358.17


GLAXO/SMITHKLINE

A PHASE III, RANDOMIZED, DOUBLE-BLIND, ACTIVE CONTROLLED, PARALLEL GROUP STUDY, COMPARING THE EFFICACY, SAFETY AND TOLERABILITY OF THE FIXED DOSE COMBINATION FF/UMEC/VI WITH THE FIXED DOSE DUAL COMBINATION OF FF/VI, ADMINISTERED ONCE-DAILY VIA A DRY POWDER INHALER IN SUBJECTS WITH INADEQUATELY CONTROLLED ASTHMA

2018 ($2,500.00) ($648.15) ($3,148.15)



YR 3: NETWORK MANAGEMENT CORE (NEMO) FOR THE PULMONARY TRIALS COOPERATIVE (PTC) (RETHINC)

2018 $1,000.00 $0.00 $1,000.00



YR 2: NETWORK MANAGEMENT CORE (NEMO) FOR THE PULMONARY TRIALS COOPERATIVE (PTC) / INSIGHT: PULMONARY TRIALS COOPERATIVE’S (PTC) INTERVENTION STUDY IN OVERWEIGHT PATIENTS WITH COPD (INSIGHT COPD) TRIAL

2018 $1,000.00 $173.33 $1,173.33



AMENDMENT - THE GENETICS EPIDEMIOLOGY OF COPD

2018 $17,643.50 $6,369.69 $24,013.19


NIH: NATIONAL INSTITUTES OF HEALTH

YR 3: NETWORK MANAGEMENT CORE (NEMO) FOR THE PULMONARY TRIALS COOPERATIVE (PTC) (INSIGHT)

2018 $1,000.00 $173.33 $1,173.33

LAZARUS, DONALD

Olympus/Spiration (EMPROVE)

Spiration Pivotal II Trial (EMPROVE) 2018 $12,596.24 $0 $12,596.24

PANDIT, LAVANNYA

UNITED THERAPEUTICS

A Randomized, Placebo-Controlled Study of Inhaled Treprostinil in Subjects with Pulmonary Hypertension due to Parenchymal Lung Disease Protocol Number: #RIN-PH-201

2017-2020 $125,000 $0 $125,000

6. Publications 1. Kheradmand F, You R, Hee Gu B, Corry DB. Cigarette Smoke and DNA Cleavage Promote Lung Inflammation and Emphysema. Trans Am Clin Climatol Assoc. 2017;128:222-33. PubMed PMID: 28790504; PMCID: PMC5525399 2. Wang DH, Lee HS, Yoon D, Berry G, Wheeler TM, Sugarbaker DJ, Kheradmand F, Engleman E, Burt BM. Progression of EGFR-Mutant Lung Adenocarcinoma is Driven By Alveolar Macrophages. Clin Cancer Res. 2017;23(3):778-88. doi: 10.1158/1078-0432.CCR-15-2597. PubMed PMID: 27496865 3. Maryam Iman, Ramazan Rezaei, Sadegh Azimzadeh, Parvin Shariati, Farrah Kheradmand, Jafar Salimian. Th17/Treg Immunoregulation and Implications in Treatment of Sulfur Mustard Gas Induced Lung Diseases. Expert Review of Clinical Immunology. 2017 Vol 13; 12: 1173-1188. 4. Liang, D; Tian, L, You, R; Halpert, M; Konduri, V; Baig, Y.; Paust, S; Kim, D; Kim, S, Jia, F; Huang, S; Zhang, X; Kheradmand, F; Corry, D; Gilbert, B; Levitt, J; Decker, W. AIMp1 Potentiates TH1 Polarization and Is Critical for Effective Antitumor and Antiviral Immunity. Front Immunol. 2017 Vol 8; 1801. 5. Kryshna Ayyagari, William P Mulmoy, AW Bracey, Cesar Castillo, James P Herlihy Perioperative Management of LVAD Patients. In Mechanical Circulatory Support for the Treatment of Advanced Heart Failure. Editor, Morgan, Jeff. Publisher: Springer Scientific, Dec 2017 6. Lockyer P, Mao H, Fan Q, Li L, Yu-Lee LY, Eissa NT, Patterson C, Xie L, Pi X. LRP1-dependent BMPER signaling regulates lipopolysaccharideinduced vascular inflammation. Arterioscler Thromb Vasc Biol, 37:1524-1535, 2017. 7. Sha Y, Rao L, Settembre C, Ballabio A, Eissa NT. STUB1 regulates TFEB-induced autophagylysosome pathway, EMBO J, 36: 2544–2552, 2017. 8. Khan A, Mann L, Papanna R, Lyu MA, Singh CR, Olson S, Eissa NT, Cirillo J, Das G, Hunter RL, Jagannath C. Mesenchymal stem cells internalize Mycobacterium tuberculosis through scavenger receptors and restrict bacterial growth through autophagy. Sci Rep, Nov 8;7(1):15010. doi: 10.1038/s41598-017-15290-z, 2017. 9. Yao C, Veleva T, Scott L Jr, Cao S, Li L, Chen G, Jeyabal P, Pan X, Alsina KM, Abu Taha I, Ghezelbash S, Reynolds CL, Shen YH, LeMaire SA, Schmitz W, Müller FU, El Armouche A, Eissa NT, Beeton C, Nattel S, Wehrens XHT, Dobrev D, Li N. Enhance Cardiomyocyte NLRP3 Inflammasome Signa ing Promotes Atrial Fibrillation. Circulation. 2018 May 25. pii: 118.035202. [Epub ahead of print]. 10. Kurihara C, Kawabori M, Ono M, Hussain ST, Parulekar AD, Morgan JA, Loor G. Lung procurement after cardiac death in a donor with previous median sternotomy. Ann Thorac Surg. 2017 Nov;104(5):e371-e373. PMID: 29054231 11. Parulekar AD, Kao CC, Diamant Z, Hanania NA. Targeting the IL-4 and IL-13 pathway in severe asthma: current knowledge and future needs. Curr Opin Pulm Med. 2017 Oct 13 [epub ahead of print]. PMID: 29036019 12. Loor G, Simpson L, Parulekar A. Bridging to Lung Transplantation with Extracorporeal Circulatory Support: When or When Not? J Thorac Dis 2017;9(9):3352-3361. 13. Medrek S, Parulekar AD, Hanania NA. Predictive Biomarkers for Asthma. Current Allergy Asthma Rep. 2017 Sep 19;17(10):69. PMID: 28929293.

14. Hoang V, Medrek SK, Pendurthi M, Kao CC, Parulekar AD. Improving Donor Lung Management and Recipient Selection in Lung Transplantation. Am J Respir Crit Care Med. 2017 Sep 15;196 (6):782-784. PMID: 28608711. 15. Hoang V, Li GW, Kao CC, Dronavalli G, Parulekar AD. Change in skeletal muscle following lung transplantation is related to underlying disease. Clin Transplant. 2017 Mar;31(3). PMID: 28017627. 16. Medrek SK, Kao CC, Yang DH, Hanania NA, Parulekar AD. Fungal sensitization is associated with increased risk of life-threatening asthma. J Allergy Clin Immunol Pract. 2017 Jul - Aug;5(4):10251031 17. Bujarski S, Parulekar A, Hanania N. “Asthma, COPD, and asthma-COPD overlap in special populations.” In: Bernstein JA, Boulet LP, Wechsler ME eds. Asthma, COPD, and the Overlap: A CasedBased Overview of Similarities and Differences. 1st ed. CRC Press; 2018: 135-144. 18. Cardenas EI, Breaux K, Da Q, Flores JR, Ramos MA, Tuvim MJ, Burns AR, Rumbaut RE, Adachi R. Platelet Munc13-4 regulates hemostasis, thrombosis and airway inflammation. Haematologica. 2018 Apr 19. pii: haemtol.2017.185637. doi: 10.3324/haematol.2017.185637. [Epub ahead of print] 19. Da Q, Derry PJ, Lam FW, Rumbaut RE. Fluorescent labeling of endogenous platelets for intravital microscopy: Effects on platelet function. Microcirculation. 2018 Apr 27:e12457. doi: 10.1111/ micc.12457. [Epub ahead of print] 20. Solaiman SS, Agrawal R Non-24-Hour SleepWake Circadian Rhythm Disorder in a Sighted Male With Normal Functioning. J Clin Sleep Med. 2018 Mar 15;14(3):483-484. doi: 10.5664/ jcsm.7008. 21. Agrawal R, Wang JA, Ko AG, Getsy JE A realworld comparison of apnea-hypopnea indices of positive airway pressure device and polysomnography. PLoS One. 2017;12 (4):e0174458. doi: 10.1371 journal.pone.0174458. 22. Hemodynamic and Pathologic Characterization of the TASK-1-/- Mouse Does Not Demonstrate Pulmonary Hypertension. Kitagawa MG, Reynolds JO, Wehrens XHT, Bryan RM Jr, Pandit LM. Front Med (Lausanne). 2017 Oct 23;4:177. 23. Admission for COPD Exacerbation Is Associated with the Clinical Diagnosis of Pulmonary Hypertension: Results from a Retrospective Longitudinal Study of a Veteran Population. Medrek SK, Sharafkhaneh A, Spiegelman AM, Kak A, Pandit LM. COPD. 2017 Oct;14(5):484-489. 24. Falce K, Guy E, Hyman D, Hotze T, Lazarus D, Bandi V, Parchem J, Davidson C, Munnur U. Bronchoscopic resection of a tracheobronchial leiomyoma in a pregnant patient. Int J Obstet Anesth. 2018; April 10 doi: 10.1016/j.ijoa.2018.04.002. PMID 29764714 [Epub ahead of print] 25. You R, DeMayo FJ, Liu J, Cho SN, Burt BM, Creighton CJ, Casal RF, Lazarus DR, Lu W, Tung HY, Yuan X, Hill AA, Kim M, Perusich S, Cornwell LD, Rosen D, Song LZ, Paust S, Diehl GE, Corry DB, Kheradmand F. IL17A regulates tumor latency and metastasis in lung adeno and squamous SQ.2b and AD.1 cancer. Cancer Immunol Res. 2018; Apr 13 doi 10.1158/2326-6066. CIR-17-0554. PMID 29653981 [Epub ahead of print] 26. Miller RJ, Casal RF, Lazarus DR. Ost DE, Eapen GA. Flexible bronchoscopy. Clin Chest Med. 2018; 1 (1): 1-16 27. Lazarus DR, Casal RF. Persistent air leaks: a review with an emphasis on bronchoscopic management. J Thorac Dis. 2017; 9 (11): 46604670.

28. Medrek SK, Lazarus DR, Zarrin-Khameh N, Mohyuddin N, Bandi V. Obstructive posttracheotomy granulation tissue. Am J Respir Crit Care Med. 2017; 196 (5): e12-e13. 29. Medrek SK, Kular HS, Lazarus DR, Bujarski S, Patel K, Bandi V. Use of sclerotherapy for the treatment of massive hemoptysis due to a bleeding bronchial varix. Ann Am Thorac Soc. 2017; 14 (7): 1221-1223. 30. Mudambi L, Lazarus DR, Eapen GA. Endobronchial ultrasound: clinical applications. In: Diaz-Jimenez JP, Rodriguez AN eds. Interventions in Pulmonary Medicine. 2nd ed. New York: Springer-Verlag; 2018: 403419. 31. Lazarus DR, Casal RF. Flexible bronchoscopy. In: Musani AI, Dutau H eds. Advances in Interventional Pulmonology. 1st ed. Book series: Frontiers in Respiratory Medicine Volume 1. Sharjah, UAE: Bentham Science Publishers; 2017: 1-19. 32. Official ERS/ATS clinical practice guidelines: noninvasive ventilation for acute respiratory failure Bram Rochwerg 1 , Laurent Brochard2,3, Mark W. Elliott4 , Dean Hess5 , Nicholas S. Hill6 , Stefano Nava7 and Paolo Navalesi8 (members of the steering committee); Massimo Antonelli9 , Jan Brozek1 , Giorgio Conti9 , Miquel Ferrer10, Kalpalatha Guntupalli11, Samir Jaber12, Sean Keenan13,14, Jordi Mancebo15, Sangeeta Mehta16 and Suhail Raoof17,18 (members of the task force) Eur Respir J 2017; 50: 1602426 J Altern Complement Med. 2017 Jul 17. doi: 10.1089/acm.2017.0102. [Epub ahead of print] 33. Effect of Yoga Breathing (Pranayama) on Exercise Tolerance in Patients with Chronic Obstructive Pulmonary Disease: A Randomized, Controlled Trial. Kaminsky DA1,2, Guntupalli KK3, Lippmann J2, Burns SM2, Brock MA3, Skelly J4, DeSarno M4, Pecott-Grimm H2, Mohsin A3, LaRockMcMahon C2, Warren P5, Whitney MC6, Hanania NA3. 34. Update in Pulmonary Medicine Evidence published in 2016 Christopher Howard, MD; Kalpalatha Guntupalli, MD Ann Inern Med 2017;166: W40W43 35. Parulekar AD, Martinez C, Tsai C, Locantore N, Atik MA, Yohannes AM, Kao CC, AlAzzawi H, Mohsin A, Wise RA, Foreman M, Demeo D, Regan EA, Make BJ, Boriek AM, Wiener E, Hanania NA. Examining the effects of age on health outcomes of COPD: results from the COPDGene and ECLIPSE Cohorts. J Am Med Dir Assoc. 2017 Dec 1;18 (12):1063- 1068. PMID: 29169736 36. Tanner MR, Tajhya RB, Huq R, Gehrmann EJ, Rodarte KE, Atik MA, Norton RS, Pennington MW, Beeton C. Prolonged immunomodulation in inflammatory arthritis using the selective Kv1.3 channel blocker HsTX1[R14A] and its PEGylated analog. Clinical Immunology 180 (2017) 45–57 37. Hanania NA, Braman S, Adams SG, et al. The role of inhalation delivery devices in COPD: Perspectives of patients and health care providers. Chronic Obstr Pulm Dis. 2018; 5(2): 111-123. 38. Braman SS, Carlin BW, Hanania NA, Mahler DA, Ohar JA, Pinto-Plata V, Shah T, Eubanks D, Dhand R. Results of a Pulmonologist Survey Regarding Knowledge and Practices With Inhalation Devices for COPD. Respir Care. 2018 May 1. pii: respcare.05717. doi:10.4187 respcare.05717. [Epub ahead of print] 39. Dhand R, Mahler DA, Carlin B, Hanania N, Ohar J, Pinto-Plata V, Shah T, Eubanks D, Braman SS. Results of a Patient Survey Regarding COPD Knowledge, Treatment Experiences, and Practices With Inhalation Devices. Respir Care. 2018 Mar 20. pii: respcare.05715. doi: 10.4187/ respcare.05715. [Epub ahead of print]

40. Cazzola M, Calzetta L, Matera MG, Hanania NA, Rogliani P. How does race/ethnicity influence pharmacological response to asthma therapies? Expert Opin Drug Metab Toxicol. 2018 Apr;14 (4):435-446 41. Yohannes AM, Kaplan A, Hanania NA. Anxiety and Depression in Chronic Obstructive Pulmonary Disease: Recognition and Management. Cleve Clin J Med. 2018 Feb;85(2 Suppl 1):S11-S18. 42. Yohannes AM, Kaplan A, Hanania NA. COPD in Primary Care: Key Considerations for Optimized Management: Anxiety and Depression in Chronic Obstructive Pulmonary Disease: Recognition and Management. J Fam Pract. 2018 Feb;67(2 Suppl):S11-S18. 43. Donohue JF, Bollu VK, Stull DE, Nelson LM, Williams VS, Stensland MD, Hanania NA. Long-term health-related quality-of-life and symptom response profiles with arformoterol in COPD: results from a 52-week trial. Int J Chron Obstruct Pulmon Dis. 2018 Feb 5;13:499-508 44. Braddock M, Hanania NA, Sharafkhaneh A, Colice G, Carlsson M. Potential Risks Related to Modulating Interleukin-13 and Interleukin-4 Signaling: A Systematic Review. Drug Saf. 2018 May;41 (5):489-509. 45. Hanania NA, Massanari M, Jain N. Measurement of fractional exhaled nitric oxide in real-world clinical practice alters asthma treatment decisions. Ann Allergy Asthma Immunol. 2018 Apr;120 (4):414-418. 46. Bousquet J, Brusselle G, Buhl R, Busse WW, Cruz AA, Djukanovic R, Domingo C, Hanania NA, Humbert M, Menzies Gow A, Phipatanakul W, Wahn U, Wechsler ME. Care pathways for the selection of a biologic in severe asthma. Eur Respir J. 2017 Dec 7;50(6). pii: 1701782. 47. Goto T, Faridi MK, Gibo K, Toh S, Hanania NA, Camargo CA Jr, Hasegawa K. Trends in 30-day readmission rates after COPD hospitalization, 2006-2012. Respir Med. 2017 Sep;130:92-97. 48. Narendra DK, Hanania NA. Procalcitonin in Chronic Obstructive Pulmonary Disease Exacerbations: Is It Ready for Primetime Use? Ann Am Thorac Soc. 2017 Dec;14(12):1757-1758. 49. Humbert M, Busse W, Hanania NA. Controversies and opportunities in severe asthma. Curr Opin Pulm Med. 2018 Jan;24(1):83-93. 50. Hanania NA, Diamant Z. The road to precision medicine in asthma: challenges and opportunities. Curr Opin Pulm Med. 2018 Jan;24(1):1-3 51. Parulekar AD, Kao CC, Diamant Z, Hanania NA. Targeting the interleukin-4 and interleukin-13 pathways in severe asthma: current knowledge and future needs. Curr Opin Pulm Med. 2018 Jan;24 (1):50-55 52. Rogers L, Sugar EA, Blake K, Castro M, Dimango E, Hanania NA, Happel KI, Peters SP, Reibman J, Saams J, Teague WG, Wise RA, Holbrook JT; American Lung Association Airways Clinical Research Centers. Step-Down Therapy for Asthma Well Controlled on Inhaled Corticosteroid and Long-Acting Beta-Agonist: A Randomized Clinical Trial. J Allergy Clin Immunol Pract. 2018 Mar - Apr;6(2):633-643. 53. Sethi S, Fogarty C, Hanania NA, et al. Efficacy of formoterol fumarate delivered by metered dose inhaler using Co-suspension™ delivery technology versus Foradil® aerolizer® in moderate-to-severe COPD: a randomized, dose-ranging study. Chronic Obstr Pulm Dis. 2017; 4(1): 2133. 54. Sharafkhaneh A. Yohannes AM, Hanania NA, Kunik ME eds. Depression and Anxiety in Patients with Chronic Respiratory Diseases. Springer 2017

55. Yohannes AM, Hanania NA. “Depression and Anxiety in Adults Patients with Asthma” In : Sharafkhaneh A. Yohannes AM, Hanania NA, Kunik ME eds. Depression and Anxiety in Patients with Chronic Respiratory Diseases. Springer 2017: 73-84 56. Bujarski S, Parulekar A, Hanania NA. “Asthma, COPD, and asthma-COPD overlap in special populations.” In: Bernstein JA, Boulet LP, Wechsler ME eds. Asthma, COPD, and the Overlap: A Cased- Based Overview of Similarities and Differences. 1st ed. CRC Press; 2018: 135-144. 57. Narendra A, Hanania NA. “Severe Acute Asthma”. In Saade GR, Belfort MA, Dildy GA, Phelan JP, Foley MR eds. Critical Care Obstetrics, 6th Edition. Wiley-Blackwell, September 2018 58. “Sacred Pause” in the ICU: Evaluation of a Ritual and Intervention to Lower Distress and Burnout. Sumit Kapoor, MD, FCCP, Christopher K. Morgan, MD, Muhammad Asim Siddique, MD, Kalpalatha K. Guntupalli, MD, FCCM, Master FCCP, MACP. 59. Lung diseases in the modern era, Chapter 10 published in ‘The Sub specialty care of HIVinfected patients’ online book, Helina Wakwaya, MD, Dharani Narendra, MD, Elizabeth Guy, MD, published February 2018 60. Update in management of severe hypoxemic respiratory failure. Published in the CHEST journal, Narendra DK, Hess Dr, Sessler CN, Belete HM, Guntupalli KK, Khusid F, Carpati CM, Astiz ME, Raoof S. 2017 Oct. ;152(4):867879. doi: 10.1016/j.chest.2017.06.039. Epub 2017 Jul 14.

7. 2017-2018 Fellowship Graduates

fffg f

k Pulmonary & Critical Care Medicine

Dr. Tim Hotze

Dr. Helina Wakwaya Dr. John Blixt

Dr. Thomas Monaco Dr. Harman Kular

Critical Care Medicine

Dr. Jonathan Suarez Dr. Prakruthi Voore

Sleep Medicine

Dr. David Adejorin Dr. Xuesong Chen

Dr. Sonal Malhotra Dr. Goutham Gudavalli

Dr. Joe Ochoa

Transition Medicine


Annual Research Report and Accomplishment Section of Transition Medicine

Department of Medicine, Baylor College of Medicine (1 July 2017–30 June 2018)

Contents Publications ................................................................................................................................................... 1

Awards/Honors ............................................................................................................................................. 1

Professional Organizations ........................................................................................................................... 2

Editorial Board Memberships/Positions ....................................................................................................... 2

Grants ............................................................................................................................................................ 2

Faculty Cynthia Peacock, MD, FACP, FAAP- Medical Director Elisha Acosta, MD Ellen Fremion, MD, FAAP Judy Kim, MD K. Jordan Kemere, MD

Publications Acosta, E; Peacock, C. (2018) Transition for Children with Medical Complexity. In: Kline MW. eds. Rudolph's Pediatrics, 23e (pp. 560-561). 2018 New York, NY: McGraw-Hill.

Fremion E, Morrison-Jacobus M, Castillo J, Castillo H, Ostermaier K. (2017) A chronic care model for spina bifida transition. J Pediatr Rehabil Med. 2017, 10(3-4):243-247.

Castillo J, Ostermaier KK, Fremion E, Collier T, Zhu H, Huang GO, Tu D, Castillo H. A. (2017) Urologic self-management through intermittent self-catheterization among individuals with spina bifida: A journey to self-efficacy and autonomy. J Pediatr Rehabil Med. 2017, 10(3-4):219-226.

Awards/Honors Fremion: “That’s the Way” Baylor College of Medicine award in recognition of exceptional care feedback from patients 11/2017 Peacock, Acosta, Fremion, Kim, Kemere: “All Star: Highest Rank” Baylor College of Medicine award for exceptional patient satisfaction, quality, and safety. Quarters 1, 2, and 4.

Professional Organizations Acosta: American Academy of Pediatrics, American College of Physicians, American Academy of Developmental Medicine and Dentistry

Fremion: Spina Bifida Association Transition to Adult Care Healthcare Guidelines Workgroup Chair (2014-2018); Spina Bifida Association provider advisory committee (2016-present), American College of Physicians, American Academy of Pediatrics, The American Academy of Developmental Medicine and Dentistry Kemere: American College of Physicians, American Academy of Developmental Medicine and Dentistry Kim: American Academy of Family Physicians, Texas Academy of Family Physicians, Harris County Academy of Family Physicians, Down Syndrome Medical Interest Group (Annual symposium committee member, 2017-2018, 2018-2019), American Academy of Developmental Medicine and Dentistry Peacock: American College of Physicians Fellow, American Academy of Pediatrics Fellow, The American Academy of Developmental Medicine and Dentistry (board member 2018-2020)

Editorial Board Memberships/Positions Peacock: American Academy of Developmental Medicine and Dentistry Board Member 2018-2020

Grants Acosta: SOI/AADMD National Curriculum in Developmental medicine, Funding Dates: 2017 Acosta, Kim: “Complex Care Transition Readiness Program”, Ligums Family Transition Medicine Grant, Co-Principle Investigators, Funding dates: October 2016-October 2017, re-funding October 2017-October 2018 Fremion: “Self-Management Improvement for Teens with Spina Bifida”, Ligums Family Transition Medicine Grant, Principle Investigator, Funding dates: October 2016-October 2017, re-funding October 2017-October 2018 Kemere: “Planning Transition in the Texas Children’s Hospital Metabolic Clinic”, Ligums Family Transition Medicine Grant, Co-Principle Investigator, Funding dates: October 2016-October 2017, re-funding October 2017-October 2018 Peacock: “Transition Health Care for Children and Youth with Special Health Care Needs”. Healthy Tomorrows Partnership for Children Program from Maternal and Child Health Bureau at HRSA, Principle Investigator, Funding dates: March 2016-2021

department of medicine anderson me, wehrens xht. oxidized camkii (ca 2+/calmodulin-dependent protein...

Documents