INFECTION AND IMMUNITYVOLUME 61 * OCTOBER 1993 * NUMBER 10
Vincent A. Fischetti, Editor in Chief(1994)
Rockefeller UniversityNew York, N.Y.
Barry I. Eisenstein, Editor (1994)Lilly Research LaboratoriesIndianapolis, Ind.
Stanley Falkow, Minireview Editor (1995)Stanford University School ofMedicineStanford, Calif.
Dexter H. Howard, Editor (1996)University of CaliforniaLos Angeles, Calif.John M. Mansfield, Editor (1998)University of WsconsinMadison, WIS.Jerry R McGhee, Editor (1994)University ofAlabamaBinningham, Ala.David C. Morrison, Editor (1997)University ofKansas Medical CenterKansas City, Kans.
Carol A. Nacy, Editor (1995)EntreMed Inc.Rockville, Md.
Alison O'Brien, Editor (1996)Uniformed Services University of theHealth Sciences
Bethesda, Md.
Philippe J. Sansonetti, Editor (1997)Institut PasteurParis, France
Soman N. Abraham (1994)Julia W. Albright (1995)Glen Armstrong (1995)Sandra K. Armstrong (1993)Joseph T. Barbleri (1995)Alan G. Barbour (1995)Scott Barnum (1995)Joel B. Baseman (1994)Robert E. Baughn (1993)Patrick Bavoil (1993)Blaine L. Beaman (1994)Jorge L. Benach (1995)D. Kay Blanchard (1995)Martin J. Blaser (1995)Arnold S. Bleiweis (1993)W. Chaunce Bogard (1995)Gregory A. Bohach (1993)Patrick Brennan (1994)David E. Briles (1994)Robert R. Brubaker (1993)DrusllHa L. Burns (1994)Gerald Byrne (1994)Richard A. Calderone (1993)Stephen Calderwood (1994)Harlan Caldwell (1993)Priscilla A. Campbell (1993)Janne G. Cannon (1993)Gail H. Cassell (1993)John Chan (1994)Bruce Chassy (1993)Ambrose Cheung (1993)Nicholas P. Cianciotto (1993)Witold Cieplak (1994)John 0. Cisar (1994)Josephine Clark-Curtiss (1993)P. Patrick Cleary (1993)Steven Clegg (1993)John D. Clements (1995)Don B. Clewell (1993)Myron S. Cohen (1993)Paul S. Cohen (1993)R. John Collier (1994)Frank M. Collins (1995)Guy Cornelis (1993)Rebecca Cox (1993)Jorge H. Crosa (1994)Jim E. Cutler (1993)
Barbara H. Iglewski, Chairman,
EDITORIAL BOARDCharles J. Czuprynski (1995)George S. Deepe, Jr. (1995)Judith E. Domer (1995)Gordon Dougan (1994)Lawrence A. Dreyfis (1993)Roman Dziarski (1993)Robert A. Eisenberg (1993)Toby K. Elsenstein (1993)John H. Eldridge (1995)Charles 0. Elson (1995)N. Cary Engleberg (1995)Joseph C. Fantone m (1993)Joseph J. Ferretti (1995)Dara W. Frank (1993)Rolf G. Freter (1993)Ronald J. Gibbons (1994)Janet R. Gilsdorf (1993)Mae Go (1993)William E. Goldman (1995)Emil Gotschllch (1994)Patrida Guerry-Kopecko (1993)Paul Gulig (1993)Thomas L. Hale (1993)Jane L. Halpern (1993)Shigeyuki Hamada (1993)Eric J. Hansen (1995)David L. Hasty (1994)Richard Hector (1995)Fred Heffron (1993)Erik Hewlett (1993)James B. Hicks (1994)Susan Hollingshead (1995)Jan Holmgren (1994)Anne Morris Hooke (1995)Ralph R. Isberg (1993)Graham Jackson (1995)Matt Jackson (1995)William R. Jacobs, Jr. (1993)James B. Kaper (1994)Stefan H. E. Kaufmann (1995)Paul M. Kaye (1994)Mogens Kilian (1993)Theo N. Kirkland (1995)Hiroshi Kiyono (1995)Dennis J. Kopecko (1995)Malak Kotb (1994)Thomas R. Kozel (1994)
Publications Board
Arnold Kreger (1995)Howard K. Kuramitsu (1994)David Lelby (1995)Myron Levine (1994)Stephen Lory (1993)Carl F. Mam (1993)Anthony Maurelli (1993)Roderick McCallum (1994)Bruce McClane (1995)John Mekalanos (1995)Eleanor S. Metcalf (1995)Suzanne M. Michalek (1995)Michael L. Misfeldt (1994)Harry Mobley (1995)Robert L. Modlin (1995)Robert N. Moore (1995)Steve L. Moseley (1993)Richard Moxon (1993)Antony J. Mukkada (1993)Martha H. Mulks (1995)Robert S. Munford (1992)Robert S. Munson (1995)Juneann W. Murphy (1993)Thalia I. Nicas (1995)Michael V. Norgard (1995)Robert North (1995)Dennis E. Ohman (1995)Andrew B. Onderdonk (1993)Paul Orndorff (1993)Michael J. Parmely (1995)Jeffrey Parsonnet (1995)Shelley M. Payne (1994)Kenneth Peterson (1993)William A. Petri, Jr. (1993)Gerald B. Pier (1995)Daniel A. Portnoy (1995)Richard A. Proctor (1993)Justin D. Radolf (1993)Reuben Ramphal (1994)Jonathan I. Ravdin (1995)Richard F. Rest (1993)Judith C. Rhodes (1995)Donald Robertson (1993)Sara W. Rothman (1993)Craig E. Rubens (1994)Michael W. Russell (1994)Roy R. B. Russell (1995)
Linda M. Illig, Director, Journals
Catharine Saelinger (1993)James Samuel (1995)Stewart Scherer (1994)Patrick SchlHevert (1993)June R. Scott (1993)Penelope G. Shackelford (1995)Alan Sher (1995)Thomas M. Shinnick (1994)Richard P. Silver (1995)Richard Silverstein (1995)Jerry Simecka (1994)Emil Skamene (1994)Jack D. Sobel (1993)P. Frederick Sparl (1993)Walter E. Stamm (1993)George Stewart (1993)Susan C. Straley (1995)Barnet M. Sultzer (1994)Catharina Svanborg (1993)John L. Swanson (1993)Yosifimi Takeda (1994)Martin A. Taubman (1993)Diane W. Taylor (1993)John Thompson (1993)Michael R. Thompson (1993)Trevor J. Trust (1994)Elaine Tuomanen (1993)Rodney K. Tweten (1993)Ivo van de Ron (1993)Thomas E. Van Dyke (1995)Jan D. A. van Embden (1994)Michael L. Vasil (1993)Peter A. Ward (1994)Alison Weiss (1995)Rodney Welch (1993)Tracy D. Wilkins (1993)Dwight Williams (1993)Peter H. Williams (1993)Mark E. Wilson (1994)Herbert H. Winkler (1995)Marcia K. Wolf (1993)Patricia L. Worsham (1993)Priscilla B. Wyrick (1993)Douglas B. Young (1994)Lowell Young (1994)H. Kirk Zeigler (1995)
Jack Kenney, Production Editor
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Author IndexAbrams, John S., 4038Adams, L. B., 4173Ally, B., 4085Alonso-Vega, Cristina, 4280Amano, Ken-Ichi, 4350Ansher, Sherry, 4240Aragon, Adam S., 4232Astagneau, P., 4498Athamna, Abed, 4208Ausiello, Clara M., 4105Azen, Edwin, 4434
Baca, Oswald G., 4232, 4485Barthold, Stephen W., 4493Bates, Janice, 4382Beaman, Miles H., 4038Beck, Deborah S., 4493Bermudez, Luiz E., 4126Bernabeu, Carmelo, 4225Bertram, G., 4263Bille, J., 4099Bohach, Gregory A., 4254Borg-von-Zepelin, Margaret,4398
Borland, Robert, 4473Brade, Helmut, 4514Brade, Lore, 4514Bridgewater, Jennifer, 4240Brown, A. J. P., 4263Brunton, J., 4085Buhler, John E., 4232Butcher, Wade G., 4119
Caldwell, Harlan D., 4406Callister, S. M., 4367Cassone, Antonio, 4105Castro, Mario, 4302Caufield, Page C., 4119Chang, A., 4293Cheng, Shuk Han, 4501Cheong, Yuet-Meng, 4527Chougnet, C., 4498Christner, Robert F., 4232Clark, Burton D., 4356Clark, C. G., 4085Clyne, Marguerite, 4051Coffey, Tracey J., 4382Collaco, Christopher R., 4427Covaro, Gail, 4126Crabb, Joseph, 4079Creasey, A. A., 4293Crusiaux, Alain, 4280Cuevas, William A., 4310
Dallas, Mary Miller, 4415Daniels, Maggie, 4382da Silveira, Jos6 Franco, 4196Datta, Manjula, 4501Davis, William C., 4254de Azavedo, J. C. S., 4085de Boer, J. P., 4293de Graaf, F. K., 4518De Graaf, L., 4167De Grandis, Stephanie, 4510De Groote, Dona, 4280Deighton, Margaret, 4473Deloron, P., 4498de Souza, Mark S., 4493Devi, Shamala, 4527Dickens, Sarah M., 4360Dinarello, Charles A., 4356Doyle, Patricia S., 4079Drumm, Brendan, 4051
Duane, Peter G., 4392Dubois, B., 4498Duchow, Jochen, 4280Dyer, Roy B., 4427Dytoc, M., 4085
Ebrahim, Jalal Seyed, 4523Eerenberg, A. J. M., 4293Eiffert, Helmut, 4523Elson, Charles O., 4272Erroi, Annalaura, 4356
Fandeur, Thierry, 4469Fantuzzi, Giamila, 4356Fasano, Alessio, 4462Fertel, Richard, 4333Fidel, Paul L., Jr., 4202Finlay, B. Brett, 4489Fisher, Susan J., 4434Fleer, A., 4167Fleischer, Bernhard, 4507Foster, John W., 4489Franco, Fuilvia R. S., 4196Frankel, Gad, 4208Friedman, Herman, 4027Fujihashi, Kohtaro, 4272Fujita, Mild, 4350Fukutomi, Y., 4173
Galen, James E., 4462Garcia-del Portillo, Francisco,
4489Gessani, Sandra, 4105Ghezzi, Pietro, 4356Gilks, Charles, 4382Giovarelli, Mirella, 4356Glew, Robert H., 4232Gnocchi, Paola, 4356Godoy, Veronica G., 4415Goldman, Michel, 4280Golenbock, Douglas T., 4452Gomez, Maria J., 4105Gooday, G. W., 4263Goudeau, Alain, 4112Gow, N. A. R., 4263Grau, Georges E., 4182Greenspan, D., 4263Greenspan, J. S., 4263Gueirard, Pascale, 4072Guiso, Nicole, 4064, 4072Gupta, Radhey S., 4225Gyles, Carlton L., 4510
Hack, C. E., 4293Hacker, Jorg, 4480Hall, Andrew C., 4326Hall, Robert H., 4326Handelsman, M. Y. C., 4085Hansen, George M., Jr., 4493Haritani, Makoto, 4153Hasty, David L., 4208Hechemy, Karim E., 4485Hermann, Elisabeth, 4507Herzog, Norbert K., 4427Hill, Priscilla J., 4045Hoffman, Orleen A., 4302Hofmann, Heidelore, 4158Hohenstein, Peter, 4217Hollander, H., 4263Holst, Otto, 4514Hunter, Christopher A., 4038Huntley, James S., 4326Husson, C6cile, 4280
Isetta, Anna, 4356
Jackson, L. A., 4338Jackson, Raymond J., 4272Janoff, Edward N., 4392Jasni, Sabri, 4286Jaton-Ogay, K., 4099Jeurissen, Suzan H. M., 4504Jones, Amanda L., 4045Jordens, J. Zoe, 4382Jouault, Thierry, 4398
Kabha, Kisra, 4208Kaper, James B., 4462Kell, Christopher M., 4382Khelef, Nadia, 4064Kim, Lucy J., 4493Kiyono, Hiroshi, 4272Klein, Michel H., 4406Klein, Thomas W., 4027Kobayashi, Yoshinao, 4058Koga, Toshihiko, 4344Konishi, Hisanori, 4147Korhonen, Timo K., 4480Kozel, Thomas R., 4360Krahenbuhl, J. L., 4173Kramer, Michael D., 4158Kruszewska, Danuta, 4188Kubo, Shigemasa, 4375Kubota, Hiroshi, 4375
Lachumanan, Ramkumar,4527
Lantz, Marilyn S., 4119Latge, J. P., 4099Lawson, Gordon H. K., 4286Lepage, Gilbert, 4398Lepers, J. P., 4498Le Scanf, C6cile, 4469Lim, L. C. L., 4367Limper, Andrew H., 4302Liu, Yannan, 4452Lopez-Bote, Juan Pedro, 4225Lopez-Guerrero, Jos6
Antonio, 4225Louie, M., 4085Lovrich, S. D., 4367Lowrie, Douglas B., 4501Lupher, Mark, 4254Lynch, Maria E., 4202Lynn, William A., 4452Lyon, Julie D., 4254
MacIntyre, Neil, 4286Mackenzie, Donald, 4398Mackie, Rebecca A., 4286Mai, G. T., 4338Makela, P. Helena, 4248Malamy, Michael H., 4415Manning, Donald S., 4093,4406
Mantle, Michele, 4131Marchant, Arnaud, 4280Marko, Michael, 4485Marr, James C., 4254Martinez-Martinez, L., 4167Matsushiro, Aizo, 4375Matsuya, Tokuzo, 4375Mattsson, E., 4167McBride, Barry C., 4139McCormack, J. G., 4338McGhee, Jerry R., 4272McKee, Mary, 4485
McOrist, Steven, 4286Mengozzi, Manuela, 4356Meyer zum Buschenfelde,Karl-Hermann, 4507
Michalski, Jane, 4462Mitchison, Denis A., 4501Monod, M., 4099Morita, Takashi, 4375Morshed, Muhammad G.,4147
Morton, Daniel J., 4033Moter, Sabine E., 4158Muotiala, Anna, 4248Murakami, Kazuhisa, 4058Murdin, Andrew D., 4406Musser, James M., 4033, 4112
Naciri, Muriel, 4440Nakai, Motoyuki, 4344Nakazawa, Teruko, 4147Neef, Natasha, 4286Neese, Lewis W., 4302Neve, Pierre, 4280Newton, Catherine A., 4027Niesel, David W., 4427
Ofek, Itzhak, 4208Ohman, Dennis E., 4208Ohnishi, Yuichi, 4375Ohta, Hirotaka, 4344Okahashi, Nobuo, 4344Okazaki, Ken-Ichi, 4058Orencole, Scott F., 4356Ortiz, Maria Antonia, 4225
Paez, Eduardo, 4225Pang, Tikki, 4527Paranhos-Bacalla, Glaucia S.,
4196Paris, S., 4099Park, Jaechan, 4333Park, Yoonsuk, 4139Parkkinen, Jaakko, 4480Parnell, Michael J., 4406Paul, John, 4382Peeters, Carla, 4217Peeters, Johan E., 4440Perfect, John R., 4446Petersen, Carolyn, 4079Pfrommer, Gail S. T., 4360Pier, G. B., 4338Piguet, Pierre F., 4182Poolman, Jan T., 4217Poulain, Daniel, 4398Prabhakar, R., 4501Prakobphol, Akraporn, 4434Probst, Peter, 4507
Quentin, Roland, 4112
Remington, Jack S., 4038,4126
Rikihisa, Yasuko, 4333Roberson, Jerry R., 4254Rodda, Stuart J., 4527Roem, D., 4293Roman, Miriam J., 4232, 4485Rombough, Charlane, 4131Rosenau, Agnes, 4112Rubins, Jeffrey B., 4392Rude, Thomas H., 4446Russo, Thomas A., 4415Ryser, Jean Etienne, 4182
i
ii AUTHOR INDEX INFECT. IMMUN.
Samsonoff, William A., 4485Sanglard, D., 4099Sathyamoorthy, Venugopal,
4326Schaible, Ulrich E., 4158Schell, R. F., 4367Schlott, Thilo, 4523Scriba, Marianne, 4523Senaldi, Giorgio, 4182Seow, W. K., 4338Sherman, P., 4085Simon, Markus M., 4158Sironi, Marina, 4356Sizaret, Pierre Yves, 4112Smith, Abigail L., 4493Snoy, Phil, 4240Sobel, Jack D., 4202Songer, J. Glenn, 4310Spagnoli, Giulio C., 4105Spratt, Brian G., 4382
Standing, Joseph E., 4302Stewart, Scott J., 4093Stull, Terrence L., 4033Su, Hua, 4406Suto, Tsunehisa, 4350Swamy, Raji, 4501Switalski, Lech M., 4119Swoboda, R. K., 4263
Tacchini-Cottier, Fabienne,4182
Tagawa, Yuichi, 4153Taylor, F. B., Jr., 4293Thompson, Walter, 4240Thong, Y. H., 4338Timmerman, C. P., 4167Toffaletti, Dena L., 4446Trinel, Pierre-Andre, 4398Turco, Jenifer, 4317
Tylewska-Wierzbanowska,Stanislawa K., 4188
Urbani, Francesca, 4105
van der Biezen, Jenny, 4217van der Ley, Peter, 4217van Heeckeren, Anna M.,
4333Vanopdenbosch, Emmanuel,
4440Van Strijp, J. A. G., 4167Vazeux, Gilles, 4469Verbrugh, H. A., 4167Verhoef, J., 4167Vermeulen, Arno N., 4504Vervelde, Lonneke, 4504Vesin, Christian, 4182Villacorta, Isabel, 4440Virkola, Ritva, 4480
Walker, K. Barry, 4501Wallich, Reinhard, 4158Weisel, Heather R., 4392Widen, Raymond H., 4027Willemsen, P. T. J., 4518Wilson, Michael A., 4360Winkler, Herbert H., 4317Woods, Donald E., 4045Wozniak, Daniel J., 4208
Xu-Amano, Jiangchun, 4272
Yamauchi, Lucy M., 4196Yee, Arlene J., 4510Yokota, Masataka, 4147Yoshida, Nobuko, 4196Young, Bryan J., 4360Yuasa, Noboru, 4153
Zychlinsky, Arturo, 4064
Call for Papers...
CLINICAL AND DIAGNOSTIC LABORtATORY IMMUNOLOTBY
The American Society for Microbiology will commence publication of a bimonthly journal, Clinical andDiagnostic Laboratory Immunology, in January 1994 that will bring together information on the latestdevelopments in human immune response assessment, including indications for testing, methods, andinterpretation of results.
Peer-reviewed research articles describing the laboratory diagnostic aspects of the following will be featurpd-¶* humoral and cellular immunity, including specific immune cell functions (B cells, T cells, and their subsets* mediators and cytokines, complement components, and other serum proteins* natural killer cells, monocytes/macrophages, nautrophils, and myeloid cells* immune responses to infection caused by bacteria, viruses, fungi, and parasites* AIDS and other retroviral diseases* primary and secondary immunodeficiency disordersevaluation of hypersensitivity and autoimmune diseases
* histocompatibility and transplantation immunology* lymphoreticular malignancies and cancer immunology* immunogenetic testing applied to human disease diagnosis and evaluationimmunologic monitoring, including flow cytometry and vaccine ther4pylaboratory immunology as related to allergy, dermatology, immunohemafology,Ahev.oral medicine, and other medical and surgical subspeciafties .''
Novel animal models relevant to the diagnosis of human diss: weimmune response, new or evolving technology in diagnostic mOtbds1responses and/or values, case reports, quality control, and biosastcs suitablebtpjournal.
Minireviews, guest commentaries, and letters to the wil be Incuded
Editor In Chief: Steven D. Douglas. Editors: James Fols, David ENOma9psel, 4 'aseDaniel P. Stites, and Theresa L. Whiteside.
Editorial Board: P. W. Askenase, J.-F. Bach, Z. H. Berwtwioh §i. F. Bo AA. urei,D. E. Campbell, C. B. Carpenter, W. S. Ceglowski, 1.JChecL , L.C kc,t rCrmi
Rundles, B. Detrick, J. Y. Djeu, P. Dore-Duffy, A.-Etzionif3. I, Fahe T.k ItP J. felsburg, -T. A. Fleisher, M. M. Frank, H. Friedman, P. C. Gas, B. C GilRI", J. A Q*et, Riht4 L. 0gOpyQR. J. Harbeck, R. B. Herberman, R. L. Hodinka, T.N,of,nt, Pu $rbis*, Je Q. Je,¶IN. R. Kamani, D. F. Keren, T. Kishimoto, P. Lalezar, A.L dy, S:A L,;-MM. S. Leffell, J. A. Levy, S. A. Lobel, L F. Macyer, :J. B. ,t umur& ,L. M. Pachman, J. E. W. Palmblad, G. M. Penn, R. Pay,J. B, Kf rs A,Pk#ffp1C. D. Platsoucas, S. A. Plotkin, H. E. Prince, B. S.Rabin,,E. ReAs.,R. F. Schell, R. T. Schooley, P. H. Schur, S. A. Schwartz, N.W *aj. LEilr,E. R. Stiehm, J. Verhoef, G. Virella, G. N. Vyas, M. E. We A. Pae nrD. Zucker-Franklin, S. H. Zuckerman, and B. Zweimarn. . :-Pazner,
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