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Organ-on-Chip
For Personalized Medicine
Beyond borders
Janny van den Eijnden-van Raaij
Managing Director hDMT
Vlaams-Nederlandse wetenschaps-en innovatiedag
Brussel, 28 October 2019
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Organ-on-Chip Technology for Personalized Health Care
The Problem
Lack of drugs
Drug failure
Ineffective Drugs
Fatal side effects
The Solution
Organ-on-Chip
Technology
Benefit for Society
Cheaper Health Care
Business and jobs
Less animal experiments
Benefit for Patients
Personalized Health Care
Benefit for Drug Development
Faster and better
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Collaboration
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H2020 Future and Emerging Technologies (FET-open-03) program
CSA Coordination and Support Action (2 yr, 0.52M, start 1 October 2017)
ORCHID - ORgan-on-CHip In Development
Goal:1. Build a network/community of
academia, research institutes,
industry, regulatory bodies, patient
organizations, …..
2. Create a roadmap for Organ-on-Chip
technology
3. Raise awareness by dissemination
and communication
This project has received funding from the European Union's Horizon 2020 research and innovation programme
under grant agreement No 766884.
www.H2020-orchid.eu
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5 100
Specifications Qualification StandardizationProduction &
UpscalingAdoption
years
Initial
development Applications
Academia
OoC
companies
Manufacturing
companies
Pharma
Food
Cosmetics
Environment
Clinic
Academia
Generic and standardized open technology platforms
Ready-to-use OoC devicesReady-to-use OoC
devices
Organ-on-Chip roadmapBuilding blocks
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Qualification
Bridging the gap between developers and end users
OoC
developersEnd users
Regulatory agencies
(FDA, EMA)
Regulatory agencies
(FDA, EMA)
Testing & Qualification
infrastructure
EOCI
Testing & Qualification
infrastructure
EOCI
Unified qualification requirementsUnified qualification requirements
Qualified and
fit-for-purpose
models
All developed models
Stakeholder
communities
Publicly available data
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Standardization
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Production and upscalingFrom lab to market
Bridging the valley of death
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Thank you!