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Supplementary Figure 2

14 days in culture

A B

21 days in culture

A B

C D

SF2.Invasion of different types of OSCC cell lines into fibroblast populated DED-based connective tissue after 14 and 21 days culture at an air-to-liquid interface. A) SCC9, B) SCC25, C) PE/CA-PJ34, D) FaDu, E) SCC4Arrows point to invading cancer cells except in 14 day panel E (SCC4) where * donates necrotic area in SCC4. Scale bar = 200µm

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