drugbank biotech products

21
DrugBan k ID Name CAS Number Weight Formula Structure Categories Therapeutic Indication DB00106 Abarelix 183552-38-7 1416.0630 C 72 H 95 ClN 14 O 14 Anti-Testosterone Agents / Antineoplastic Agents For palliative treatment of advanced prostate cancer. DB01281 Abatacept 332348-12-6 92000.0000 Antirheumatic Agents For the management of the signs and symptoms of moderate-to-severe active rheumatoid arthritis, inducing major clinical response, slowing the progr... DB00054 Abciximab 143653-53-6 145651.1000 C 6462 H 9964 N 1690 O 2049 S 48 Anticoagulants / Antiplatelet Agents Abciximab is indicated as an adjunct to percutaneous coronary intervention for the prevention of cardiac ischemic complications in patients undergo... DB00051 Adalimumab 331731-18-1 144190.3000 C 6428 H 9912 N 1694 O 1987 S 46 Antirheumatic Agents / Immunomodulatory Agents For treatment of rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, and Crohn's disease. DB00103 Agalsidase beta 104138-64-9 45351.6000 C 2029 H 3080 N 544 O 587 S 27 Enzyme Replacement Agents For treatment of Fabry's disease (alpha-galactosidase A deficiency)

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Page 1: DrugBank Biotech Products

DrugBank ID

Name

CAS Number

Weight

Formula

Structure Categories Therapeutic Indication

DB00106Abarelix 

183552-38-7

1416.0630

C72H95ClN14O14

Anti-Testosterone Agents / Antineoplastic Agents

For palliative treatment of advanced prostate cancer.

DB01281Abatacept 

332348-12-6

92000.0000 Antirheumatic Agents

For the management of the signs and symptoms of moderate-to-severe active rheumatoid arthritis, inducing major clinical response, slowing the progr...

DB00054Abciximab 

143653-53-6

145651.1000

C6462H9964N1690O2049S48

Anticoagulants / Antiplatelet Agents

Abciximab is indicated as an adjunct to percutaneous coronary intervention for the prevention of cardiac ischemic complications in patients undergo...

DB00051Adalimumab 

331731-18-1

144190.3000

C6428H9912N1694O1987S46

Antirheumatic Agents / Immunomodulatory Agents

For treatment of rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, and Crohn's disease.

DB00103Agalsidase beta 

104138-64-9

45351.6000

C2029H3080N544O587S27

Enzyme Replacement Agents

For treatment of Fabry's disease (alpha-galactosidase A deficiency)

DB00041Aldesleukin 

85898-30-2

15314.8000

C690H1115N177O202S6

Antineoplastic AgentsFor treatment of adults with metastatic renal cell carcinoma.

Page 2: DrugBank Biotech Products

DB00092Alefacept 

222535-22-0

51801.1000

C2306H3594N610O694S26

Immunomodulatory Agents / Immunosuppressive Agents

As an immunosuppressive drug, Alefacept can be used for treatment of moderate to severe chronic plaque psoriasis

DB00087Alemtuzumab 

216503-57-0

145453.8000

C6468H10066N1732O2005S40

Antineoplastic Agents

Alemtuzumab (Campath) is a monoclonal antibody therapy used for treatment of B-cell chronic lymphocytic leukemia.

DB00088Alglucerase 

37228-64-1

55597.4000

C2532H3854N672O711S16

Enzyme Replacement Agents

For the treatment of Gaucher's disease (deficiency in glucocerebrosidase)

DB01272Alglucosidase alfa 

420784-05-0

105270.8020

C4758H7262N1274O1369S35

Enzyme Replacement Agents

For the treatment of Pompe disease (GAA deficiency) in infants and pediatric patients.

DB00058

Alpha-1-proteinase inhibitor 

9041-92-3

44324.5000

C2001H3130N514O601S10

Enzyme Replacement Agents

For treatment of panacinar emphysema

DB00009Alteplase 

105857-23-6

59042.3000

C2569H3928N746O781S40

Thrombolytic Agents

For management of acute myocardial infarction, acute ischemic strok and for lysis of acute pulmonary emboli

Page 3: DrugBank Biotech Products

DB00026Anakinra 

143090-92-0

17257.6000

C759H1186N208O232S10

Antirheumatic Agents / Immunomodulatory Agents

For the treatment of adult rheumatoid arthritis.

DB00029Anistreplase 

81669-57-0

59042.3000

C2569H3928N746O781S40

Thrombolytic Agents

For lysis of acute pulmonary emboli, intracoronary emboli and management of myocardial infarction

DB00025Antihemophilic Factor

264725.5000

C11794H18314N3220O3553S83

Coagulants / Thrombotic Agents

For the treatment of hemophilia A, von Willebrand diseae and Factor XIII deficiency

DB00098Antithymocyte globulin

Immunomodulatory Agents

For prevention of renal transplant rejection

DB06692Aprotinin 

9087-70-1

6511.4390

C284H432N84O79S7

Antifibrinolytic Agents

For prophylactic use to reduce perioperative blood loss and the need for blood transfusion in patients undergoing cardiopulmonary bypass in the cou...

DB00113Arcitumomab 

154361-48-5

144482.5000

C6398H9900N1714O1995S54

Diagnostic Agents / Imaging Agents

For imaging colorectal tumors

Page 4: DrugBank Biotech Products

DB00023Asparaginase 

9015-68-3

31731.9000

C1377H2208N382O442S17

Antineoplastic AgentsFor treatment of acute lympocytic leukemia and non-Hodgkins lymphoma

DB00074Basiliximab 

152923-56-3

143801.3000

C6378H9844N1698O1997S48

Immunomodulatory Agents / Immunosuppressive Agents

For prophylactic treatment of kidney transplant rejection

DB00102Becaplermin 

165101-51-9

12294.4000

C532H892N162O153S9

Anti-Ulcer Agents / Topical

For topical treatment of skin ulcers (from diabetes)

DB00112Bevacizumab 

216974-75-3

Antiangiogenesis Agents / Antineoplastic Agents

As part of combination therapy for metastatic colorectal cancer and HER2-negative metastatic breast cancer.

DB00006Bivalirudin 

128270-60-0

2180.2853

C98H138N24O33

Anticoagulants / Antithrombotic Agents

For treatment of heparin-induced thrombocytopenia

DB00083

Botulinum Toxin Type A 

93384-43-1

149322.7000

C6760H10447N1743O2010S32

Anti-Wrinkle Agents / Antidystonic Agents / Neuromuscular Blocking Agents

For the treatment of cervical dystonia in adults to decrease the severity of abnormal head position and neck pain associated with cervical dystonia...

Page 5: DrugBank Biotech Products

DB00042

Botulinum Toxin Type B 

93384-44-2

150804.0000 Antidystonic Agents

For the treatment of patients with cervical dystonia to reduce the severity of abnormal head position and neck pain associated with cervical dystonia.

DB06719Buserelin 

57982-77-1

DB06168Canakinumab 

914613-48-2

145200.0000

C6452H9958N1722O2010S42

Investigated for use/treatment in rheumatoid arthritis, juvenile rheumatoid arthritis, inflammatory disorders (unspecified), and autoimmune diseases.

DB00089Capromab 

145464-28-4Imaging Agents

For diagnosis of prostate cancer and detection of intra-pelvic metastases.

DB00050Cetrorelix 

120287-85-6

1491.0900

C72H96ClN17O16

Infertility Agents / Hormone Antagonists

For the inhibition of premature LH surges in women undergoing controlled ovarian stimulation

DB00002Cetuximab 

205923-56-4

145781.6000

C6484H10042N1732O2023S36

Antineoplastic Agents

For treatment of EGFR-expressing metastatic colorectal cancer in patients who are refractory to other irinotecan-based chemotherapy regimens. Cetux...

DrugBank ID

Name

CAS Number

Weight

Formula

Structure Categories Therapeutic Indication

DB00097

Choriogonadotropin alfa 

177073-44-8

25719.7000

C1105H1770N318O336S26

Fertility Agents / Gonadotropins

For the treatment of female infertility

Page 6: DrugBank Biotech Products

DB00100

Coagulation Factor IX 

9001-28-9

46548.2000

C2041H3136N558O641S25

Coagulants / Thrombotic Agents

For treatment of hemophilia (Christmas disease).

DB00036

Coagulation factor VIIa 

9001-25-6

45079.1000

C1972H3076N560O597S28

Coagulants / Thrombotic Agents

For treatment of hemorrhagic complications in hemophilia A and B

DB00048Collagenase 

9001-12-1

112023.2000

C5028H7666N1300O1564S21

Anti-Ulcer Agents / Topical

Used to promote debridement of necrotic tissue in the treatment of severe burns and dermal ulcers including decubitus ulcers.

DB01285Corticotropin 

9002-60-2

4541.0658

C207H308N56O58SDiagnostic Agents

For use as a diagnostic agent in the screening of patients presumed to have adrenocortical insufficiency.

DB01284Cosyntropin 

16960-16-0

2933.4370

C136H210N40O31SDiagnostic Agents

For use as a diagnostic agent in the screening of patients presumed to have adrenocortical insufficiency.

DB00091Cyclosporine 

59865-13-3

1202.6112

C62H111N11O12

Antirheumatic Agents / Immunomodulatory Agents / Enzyme Inhibitors / Dermatologic Agents / Immunosuppressive Agents / Antifungal Agents

For treatment of transplant rejection, rheumatoid arthritis, severe psoriasis

DB00111Daclizumab 

152923-56-3

142612.1000

C6332H9808N1678O1989S42

Immunomodulatory Agents / Immunosuppressive Agents

Zenapax is a humanized monoclonal antibody used for prevention of renal transplant rejection

DB00080Daptomycin 

103060-53-3

1620.6706

C72H101N17O26Anti-Bacterial Agents

For the treatment of complicated skin and skin structure infections caused by susceptible strains of Gram-positive microorganisms.

Page 7: DrugBank Biotech Products

DB00012Darbepoetin alfa 

11096-26-7

18396.1000

C815H1317N233O241S5Antianemic Agents

For the treatment of anemia (from renal transplants or certain HIV treatment)

DB04932Defibrotide 

83712-60-1Antithrombotic Agents

Defibrotide is used to treat or prevent a failure of normal blood flow (occlusive venous disease, OVD) in the liver of patients who have had bone m...

DB00004Denileukin diftitox 

173146-27-5

57647.3000

C2560H4042N678O799S17Antineoplastic Agents

For treatment of cutaneous T-cell lymphoma

DB00035Desmopressin 

16679-58-6

1069.2170

C46H64N14O12S2

Renal Agents / Hemostatics / Antidiuretic Agents

Oral formulations may be used to manage primary nocturnal enuresis in adults and vasopressin sensitive diabetes insipidus, and for control of tempo...

DB00076Digoxin Immune Fab

47301.7000

C2085H3223N553O672S16Digoxin Antidote

For treatment of digitoxin overdose or digitalis glycoside toxicity.

DB00003Dornase Alfa 

9003-98-9

29253.9000

C1321H1999N339O396S9Enzyme

Used as adjunct therapy in the treatment of cystic fibrosis.

DB00055Drotrecogin alfa 

60202-16-6

55000.0000

C1786H2779N509O519S29Antisepsis Agents

For reduction of mortality in patients with severe sepsis.

Page 8: DrugBank Biotech Products

DB00095Efalizumab 

214745-43-4

Immunomodulatory Agents / Immunosuppressive Agents

For the treatment of adult patients with moderate to severe chronic plaque psoriasis, who are candidates for phototherapy or systemic therapy.

DB00109Enfuvirtide 

159519-65-0

4491.8760

C204H301N51O64

Anti-HIV Agents / HIV Fusion Inhibitors

Enfuvirtide is an antiretroviral drug used in combination therapy for the treatment of HIV-1/AIDS.

DB00016Epoetin alfa 

113427-24-0

18396.1000

C815H1317N233O241S5Antianemic Agents

For treatment of anemia (from renal transplants or certain HIV treatment)

DB00063Eptifibatide 

188627-80-7

831.9620

C35H49N11O9S2

Anticoagulants / Antiplatelet Agents / Platelet Aggregation Inhibitors

For treatment of myocardial infarction and acute coronary syndrome.

DB00005Etanercept 

185243-69-0

51234.9000

C2224H3475N621O698S36

Antirheumatic Agents / Immunomodulatory Agents

For treatment of severe active rheumatoid arthritis in adults, severe juvenile idiopathic arthritis, ankylosing spondylitis, and severe plaque psor...

DB01276Exenatide 

141758-74-9

4186.6000

C184H282N50O60S

Indicated as adjunctive therapy to improve glycemic control in patients with Type 2 diabetes mellitus who are taking metformin, a sulfonylurea, or ...

DB00093Felypressin 

56-59-7

1040.2190

C46H65N13O11S2

Renal Agents / Vasoconstrictor Agents

For use as an alternative to adrenaline as a localising agent, provided that local ischaemia is not essential.

Page 9: DrugBank Biotech Products

DB00099Filgrastim 

143011-72-7

18802.8000

C845H1343N223O243S9

Immunomodulatory Agents / Anti-Infective Agents / Antineutropenic Agents

Increases leukocyte production, for treatment in non-myeloid cancer,neutropenia and bone marrow transplant

DB00066Follitropin beta 

9002-68-0

22672.9000

C975H1513N267O304S26Fertility Agents

For treatment of female infertility

DB01279Galsulfase 

552858-79-4

56000.0000

C2534H3851N691O719S16

Enzyme Replacement Agents

For the treatment of adults and children with Mucopolysaccharidosis VI.

DB00056

Gemtuzumab ozogamicin 

220578-59-6

Antineoplastic Agents

For treatment of CD33-positive acute myeloid leukemia in patients 60 and over who are not candidates for other chemotherapy.

DB05259Glatiramer Acetate 

147245-92-9

623.6505

C25H45N5O13

Immunosuppressive Agents / Adjuvants, Immunologic

For reduction of the frequency of relapses in patients with Relapsing-Remitting Multiple Sclerosis.

DB00040

Glucagon recombinant 

9007-92-5

3767.1000

C165H249N49O51S1Antihypoglycemic Agents

For treatment of severe hypoglycemia, also used in gastrointestinal imaging

DB00075Muromonab 

140608-64-6

146189.7000

C6460H9946N1720O2043S56

Immunomodulatory Agents / Immunosuppressive Agents

For treatment of organ transplant recipients, prevention of organ rejection

Page 10: DrugBank Biotech Products

DB00108Natalizumab 

189261-10-7

Immunomodulatory Agents

For treatment of multiple sclerosis.

DB04899Nesiritide 

124584-08-33464.0000 Cardiac drugs

For the intravenous treatment of patients with acutely decompensated congestive heart failure who have dyspnea at rest or with minimal activity.

DB00104Octreotide 

83150-76-9

1019.2390

C49H66N10O10S2

Anabolic Agents / Hormone Replacement Agents / Gastrointestinal Agents / Antineoplastic Agents, Hormonal

For treatment of acromegaly and reduction of side effects from cancer chemotherapy

DB00043Omalizumab 

242138-07-4

145058.2000

C6450H9916N1714O2023S38

Anti-Asthmatic Agents / Immunomodulatory Agents

For treatment of asthma caused by allergies

DB00038Oprelvekin 

145941-26-0

19047.2000

C854H1411N253O235S2Coagulants / Thrombotics

Increases reduced platelet levels due to chemotherapy

DB00045 OspA lipoprotein27743.1000

C1198H2012N322O422S2Vaccines

For prophylactic treatment of Lyme Disease

DB00107Oxytocin 

50-56-6

1007.1870

C43H66N12O12S2

Anti-tocolytic Agents / Labor Induction Agents / Oxytocics

To assist in labor, elective labor induction, uterine contraction induction

DB00039Palifermin 

162394-19-6

16192.7000

C721H1142N202O204S9Antimucositis Agents

For treatment of oral mucositis associated with chemotherapy and radiation therapy.

Page 11: DrugBank Biotech Products

DB00110Palivizumab 

188039-54-5Antiviral Agents

For prophylaxis of respiratory diseases casued by respiratory syncytial virus.

DB00085Pancrelipase 

53608-75-6

131125.6000

C5850H8902N1606O1739S49

Enzyme Replacement Agents

For treatment of cystic fibrosis, chronic pancreatitis,and pancreatic duct blockage

DB01269Panitumumab 

339177-26-3Antineoplastic Agents

For the treatment of EGFR-expressing, metastatic colorectal carcinoma that is refractory to fluoropyrimidine-, oxaliplatin-, and irinotecan- contai...

DB00061Pegademase bovine 

9026-93-1

40788.2000

C1821H2834N484O552S14

Enzyme Replacement Agents

For treatment of adenosine deaminase deficiency

DB04895Pegaptanib 

222716-86-150000.0000

For the treatment of neovascular (wet) age-related macular degeneration.

DB00059Pegaspargase

130167-69-0

31731.9000

C1377H2208N382O442S17Antineoplastic Agents

For treatment of acute lymphoblastic leukemia

DB00019Pegfilgrastim 

208265-92-3

18802.8000

C845H1343N223O243S9

Anti-Infective Agents / Antineutropenic Agents / Immunomodulatory Agents

Increases leukocyte production, for treatment in non-myeloid cancer, neutropenia and bone marrow transplant

Page 12: DrugBank Biotech Products

DB00008

Peginterferon alfa-2a 

198153-51-4

60000.0000

Antineoplastic Agents / Antiviral Agents / Immunomodulatory Agents

For treatment of hairy cell leukemia, malignant melanoma, and AIDS-related Kaposi's sarcoma.

DB00022

Peginterferon alfa-2b 

99210-65-8

31000.0000

Antineoplastic Agents / Antiviral Agents / Immunomodulatory Agents

For the treatment of chronic hepatitis C in patients not previously treated with interferon alpha who have compensated liver disease and are at lea...

DB00082Pegvisomant 

218620-50-9

22129.0000

C990H1532N262O300S7

Anabolic Agents / Hormone Replacement Agents

Pegvisomant is a growth hormone receptor antagonist used for the treatment of acromegaly.

DB01278Pramlintide 

151126-32-8

3949.3896

C171H267N51O53S2

For the treatment of type 1 and type 2 diabetes mellitus as an adjunct to preprandial insulin therapy in patients without adequate glycemic control...

DB01270Ranibizumab 

347396-82-1

48349.6110

C2158H3282N562O681S12

For the treatment of patients with neovascular (wet) age-related macular degeneration.

DB00049Rasburicase 

134774-45-1

34109.5000

C1521H2381N417O461S7Antihyperuricemic Agents

For treatment of hyperuricemia, reduces elevated plasma uric acid levels (from chemotherapy)

DB00015Reteplase 

133652-38-7

39589.6000

C1736H2671N499O522S22Thrombolytic Agents

For lysis of acute pulmonary emboli, intracoronary emboli and management of myocardial infarction

Page 13: DrugBank Biotech Products

DB00073Rituximab 

174722-31-7

143859.7000

C6416H9874N1688O1987S44Antineoplastic Agents

For treatment of CD20-positive non-Hodgkins lymphoma, chronic lymphocytic leukemia, and rheumatoid arthritis.

DB00017Salmon Calcitonin 

47931-85-1

3431.8530

C145H240N44O48S2

Antiosteporotic Agents / Antihypocalcemic Agents / Bone Density Conservation Agents

For the treatment of post-menopausal osteoporosis

DB00020Sargramostim 

83869-56-1

14434.5000

C639H1006N168O196S8

Immunomodulatory Agents / Antineoplastic Agents / Anti-Infective Agents

For the treatment of cancer and bone marrow transplant

DB00057

Satumomab Pendetide 

138955-26-7

141478.9000

C6268H9708N1666O1971S48Imaging Agents

For diagnosis of extrahepatic malignant cancers

DB00021 Secretin3056.4000

C130H219N43O42Diagnostic Agents

For diagnosis of pancreatic exocrine dysfunction and gastrinoma

DB00010Sermorelin 

86168-78-7

3357.8820

C149H246N44O42S

Anabolic Agents / Hormone Replacement Agents

For the treatment of dwarfism, prevention of HIV-induced weight loss

DB00096Serum albumin 

9048-49-1

66472.2000

C2936H4624N786O889S41Serum substitutes

For treatment of severe blood loss, hypervolemia, hypoproteinemia.

DB00014Goserelin 

65807-02-5

1269.4105

C59H84N18O14

Antineoplastic Agents / Antineoplastic Agents, Hormonal

Breast cancer; Prostate carcinoma; Endometriosis

Page 14: DrugBank Biotech Products

DB00062

Human Serum Albumin 

9048-49-1

66472.2000

C2936H4624N786O889S41Serum substitutes

For treatment of severe blood loss, hypervolemia, hypoproteinemia

DB00070Hyaluronidase 

488712-31-8

53870.9000

C2455H3775N617O704S21

Anesthetic Adjuvants / Permeabilizing Agents

For increase of absorption and distribution of other injected drugs and for rehydration.

DB00078Ibritumomab 

174722-31-7

143375.5000

C6382H9830N1672O1979S54Antineoplastic Agents

For treatment of non-Hodgkin's lymphoma

DB01271Idursulfase 

50936-59-9

76000.0000

C2654H4000N688O774S14

Enzyme Replacement Agents

For the treatment of Hunter syndrome in adults and children ages 5 and older.

DB00053Imiglucerase 

143003-46-7

55597.4000

C2532H3854N672O711S16

Enzyme Replacement Agents

For the treatment of Gaucher's disease (deficiency in glucocerebrosidase)

DB00065Infliximab 

170277-31-3

144190.3000

C6428H9912N1694O1987S46

Immunomodulatory Agents / Immunosuppressive Agents

To manage the signs and symptoms, as well as to induce and maintain clinical remission in adults with moderate to severe active Crohn's disease or ...

DB01307Insulin Detemir 

169148-63-4 C267H402N64O76S6

Hypoglycemic Agents / Antidiabetic

For the treatment of type 1 or 2 diabetes mellitus. May be used in combination with oral anti-diabetic agents in type 2 diabetic patients who are n...

Page 15: DrugBank Biotech Products

DB00047Insulin Glargine

160337-95-1

6063.0000

C267H408N72O77S6

Hypoglycemic Agents / Antidiabetic

For the treatment of Type 1 or 2 diabetes mellitus in patients over 17 years old who require a long-acting (basal) insulin for the control of hyper...

DB01309Insulin Glulisine 

207748-29-6 C258H384N64O78S6

Hypoglycemic Agents / Antidiabetic

For the treatment of Type 1 and 2 diabetes mellitus. Should be used in regimens including a long-acting or basal insulin analogue unless it is used...

DB00046Insulin Lispro 

133107-64-9

5808.0000

C257H387N65O76S6

Hypoglycemic Agents / Antidiabetic

For the treatment of Type 1 or 2 diabetes mellitus. To be used in conjunction with an intermediate or long-acting insulin except when used in a con...

DB00030Insulin recombinant 

9004-10-8

5795.6000

C257H387N65O76S6Hypoglycemic Agents

For treatment of Type I and II diabetes mellitus.

DB00071Insulin, porcine

9004-14-2

5795.6000

C257H387N65O76S6Hypoglycemic Agents

For the treatment of type I and II diabetes mellitus.

DB00034

Interferon Alfa-2a, Recombinant 

77907-69-8

19241.1000

C860H1353N227O255S9

Antineoplastic Agents / Antiviral Agents

For the treatment of chronic hepatitis C, hairy cell leukemia, AIDS-related Kaposi's sarcoma, and chronic myelogenous leukemia. Also for the treatm...

Page 16: DrugBank Biotech Products

DB00105

Interferon Alfa-2b, Recombinant 

99210-65-8

19271.0000

C860H1353N229O255S9

Antineoplastic Agents / Immunomodulatory Agents / Antiviral Agents

For the treatment of hairy cell leukemia, malignant melanoma, and AIDS-related Kaposi's sarcoma.

DB00011Interferon alfa-n1 

74899-72-2

19241.1000

C860H1353N227O255S9

Immunomodulatory Agents / Antiviral Agents

For treatment of venereal or genital warts caused by the Human Papiloma Virus

DB00018 Interferon alfa-n3Antineoplastic Agents / Immunomodulatory Agents / Antiviral Agents

For the intralesional treatment of refractory or recurring external condylomata acuminata.

DB00069Interferon alfacon-1 

118390-30-0

19343.0000

C860H1353N227O255S9

Antineoplastic Agents / Immunomodulatory Agents / Antiviral Agents

For the treatment of hairy cell leukemia, malignant melanoma, and AIDS-related Kaposi's sarcoma

DB00060Interferon beta-1a 

145258-61-3

20027.0000

C908H1408N246O252S7

Immunomodulatory Agents / Antiviral Agents

For treatment of relapsing/remitting multiple sclerosis, also for condyloma acuminatum

DB00068Interferon beta-1b 

145155-23-3

20011.0000

C908H1408N246O253S6

Immunomodulatory Agents / Antiviral Agents

Interferon beta-1b is a drug used for the treatment of relapsing/remitting multiple sclerosis. It has been shown to slow the advance of the disease...

Page 17: DrugBank Biotech Products

DB00033

Interferon gamma-1b 

82115-62-6

17145.6000

C761H1206N214O225S6

Immunomodulatory Agents / Antiviral Agents

Interferon gamma-1b is used for the treatment of Chronic granulomatous disease and Osteopetrosis.

DB00028

Intravenous Immunoglobulin

9007-83-4

142682.3000

C6332H9826N1692O1980S42

Immunomodulatory Agents / Anti-Infectives

IVIg is used in the treatment of immunodeficiencies, as well as autoimmune and inflammatory disorders. These indications includes idiopathic thromb...

DB00090Laronidase 

210589-09-6

69899.4000

C3160H4848N898O881S12

Enzyme Replacement Agents

For the treatment of mucopolysaccharidosis

DB00001Lepirudin 

120993-53-5

6963.4250

C287H440N80O110S6

Anticoagulants / Antithrombotic Agents / Fibrinolytic Agents

For the treatment of heparin-induced thrombocytopenia

DB00007Leuprolide 

53714-56-0

1209.3983

C59H84N16O12

Antineoplastic Agents / Anti-Estrogen Agents

For treatment of prostate cancer, endometriosis, uterine fibroids and premature puberty

DB00044Lutropin alfa 

152923-57-4

23390.3000

C1014H1609N287O294S27Fertility Agents

For treatment of female infertility

DB01277Mecasermin 

68562-41-4

7649.0000

C331H518N94O101S7

For the long-term treatment of growth failure in pediatric patients with Primary IGFD or with GH gene deletion who have developed neutralizing anti...

DB00032Menotropins 

61489-71-2

23390.3000

C1014H1609N287O294S27Fertility Agents

For the treatment of female infertility

Page 18: DrugBank Biotech Products

DB00064

Serum albumin iodonated 

9048-49-1

66472.2000

C2936H4624N786O889S41Imaging Agents

For determination of total blood and plasma volumes

DB00052

Somatropin recombinant 

12629-01-5

22129.0000

C990H1532N262O300S7

Anabolic Agents / Hormone Replacement Agents

For treatment of dwarfism, acromegaly and prevention of HIV-induced weight loss

DB00086Streptokinase

9002-01-1

47286.7000

C2100H3278N566O669S4Thrombolytic Agents

For the treatment of acute evolving transmural myocardial infarction, pulmonary embolism, deep vein thrombosis, arterial thrombosis or emolism and ...

DB06149Teicoplanin 

61036-62-2

1879.6580

C88H97Cl2N9O33

Antibacterial Agents / Glycopeptide antibacterials

For the treatment of bacterial infections caused by susceptible microorganisms.

DB00031Tenecteplase

191588-94-0

58951.2000

C2561H3919N747O781S40Thrombolytic Agents

For treatment of myocardial infarction and lysis of intracoronary emboli

DB06285Teriparatide 

52232-67-4

4117.7150

C181H291N55O51S2

Bone Density Conservation Agents

For the treatment of osteoporosis in men and postmenopausal women who are at high risk for having a fracture. Also used to increase bone mass in me...

DB04900Thymalfasin 

62304-98-7

3108.2755

C129H215N33O55

Immunomodulatory Agents / Adjuvants, Immunologic / Antineoplastic Agents

Indicated as an adjuvant for influenza vaccine in elderly patients and as an adjuvant for both influenza and hepatitis B vaccines in chronic hemodi...

Page 19: DrugBank Biotech Products

DB00024Thyrotropin Alfa 

9002-71-5

22672.9000

C975H1513N267O304S26Diagnostic Agents

For detection of residueal or recurrent thyroid cancer

DB00081Tositumomab 

192391-48-3

143859.7000

C6416H9874N1688O1987S44Antineoplastic Agents

For treatment of non-Hodgkin's lymphoma (CD20 positive, follicular)

DB00072Trastuzumab 

180288-69-1

145531.5000

C6470H10012N1726O2013S42Antineoplastic Agents

For treatment of early stage HER2-positive breast cancer, or metastatic breast cancer that substantially overexpress HER2.

DB00094Urofollitropin 

146479-72-3

980.1620

C42H65N11O12S2Fertility Agents

For treatment of female infertility

DB00013Urokinase 

9039-53-6

31126.5000

C1376H2145N383O406S18Thrombolytic Agents

Urokinase can be used for the treatment of pulminary embolism, coronary artery thrombosis, IV catheter clearance, and venous and arterial blood clots.

DB00067Vasopressin 

11000-17-2

1050.2150

C43H67N15O12S2

Antidiuretics / Vasoconstrictor Agents / Oxytocics

For the treatment of enuresis, polyuria, diabetes insipidus, polydipsia and oesophageal varices with bleeding