dual energy ct - zol · 2020-02-27 · dual-energy ct more information about tissues....

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Dual energy CT Dr. Pieter Marchal Medische Beeldvorming ZOL

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Page 1: Dual energy CT - ZOL · 2020-02-27 · Dual-energy CT More information about tissues. Dual-energy/spectral CT systems. Dual-energy CT: material differentiation. Material specific

Dual energy CT

Dr. Pieter Marchal

Medische Beeldvorming ZOL

Page 2: Dual energy CT - ZOL · 2020-02-27 · Dual-energy CT More information about tissues. Dual-energy/spectral CT systems. Dual-energy CT: material differentiation. Material specific

Overzicht

• Inleiding

• Fysica 101

• Applicaties

• Voorbeelden

Page 3: Dual energy CT - ZOL · 2020-02-27 · Dual-energy CT More information about tissues. Dual-energy/spectral CT systems. Dual-energy CT: material differentiation. Material specific

Conventional (single energy) CT imaging

Scan acquisition

Page 4: Dual energy CT - ZOL · 2020-02-27 · Dual-energy CT More information about tissues. Dual-energy/spectral CT systems. Dual-energy CT: material differentiation. Material specific

Conventional (single energy) CT imaging

Image reconstruction

Page 5: Dual energy CT - ZOL · 2020-02-27 · Dual-energy CT More information about tissues. Dual-energy/spectral CT systems. Dual-energy CT: material differentiation. Material specific

Attenuation measurements (HU)

Page 6: Dual energy CT - ZOL · 2020-02-27 · Dual-energy CT More information about tissues. Dual-energy/spectral CT systems. Dual-energy CT: material differentiation. Material specific

Limitations of attenuation measurements

Page 7: Dual energy CT - ZOL · 2020-02-27 · Dual-energy CT More information about tissues. Dual-energy/spectral CT systems. Dual-energy CT: material differentiation. Material specific

Limitations of attenuation measurements

Variability in attenuation (HU) among SECT scanners: 10-25 HU

Page 8: Dual energy CT - ZOL · 2020-02-27 · Dual-energy CT More information about tissues. Dual-energy/spectral CT systems. Dual-energy CT: material differentiation. Material specific

Dual-energy CT

More information about tissues

Page 9: Dual energy CT - ZOL · 2020-02-27 · Dual-energy CT More information about tissues. Dual-energy/spectral CT systems. Dual-energy CT: material differentiation. Material specific

Dual-energy/spectral CT systems

Page 10: Dual energy CT - ZOL · 2020-02-27 · Dual-energy CT More information about tissues. Dual-energy/spectral CT systems. Dual-energy CT: material differentiation. Material specific

Dual-energy CT: material differentiation

Page 11: Dual energy CT - ZOL · 2020-02-27 · Dual-energy CT More information about tissues. Dual-energy/spectral CT systems. Dual-energy CT: material differentiation. Material specific

Material specific iodine images

Qualitative Iodine quantification

• Specific measurement of

tissue enhancement

• Increased tissue contrast

o Amplify subtle differences in

attenuation between normal

and abnormal tissues

o Regardless of the acquisition

time

• Images represent the mass

density (concentration)

• Opportunities

o Diagnosis

o Treatment planning

o Follow-up

Page 12: Dual energy CT - ZOL · 2020-02-27 · Dual-energy CT More information about tissues. Dual-energy/spectral CT systems. Dual-energy CT: material differentiation. Material specific

Processing

Page 13: Dual energy CT - ZOL · 2020-02-27 · Dual-energy CT More information about tissues. Dual-energy/spectral CT systems. Dual-energy CT: material differentiation. Material specific

DECT data sets

Virtual mono-chromatic images

• Simulated CT data sets resembling CT images generated from

mono-chromatic CT beam

• VMC images of lower energy (50-65 keV)

o Improve contrast between different tissues

o Enhance visualization of vessels and hyper vascular lesions

o Higher image noise and artifacts

• VMC images of higher energy

o Lower artifacts and reduced contrast between tissues

o Useful for reduction of metal artifacts

Page 14: Dual energy CT - ZOL · 2020-02-27 · Dual-energy CT More information about tissues. Dual-energy/spectral CT systems. Dual-energy CT: material differentiation. Material specific

Monochromatic images

Page 15: Dual energy CT - ZOL · 2020-02-27 · Dual-energy CT More information about tissues. Dual-energy/spectral CT systems. Dual-energy CT: material differentiation. Material specific

Monochromatic images

Page 16: Dual energy CT - ZOL · 2020-02-27 · Dual-energy CT More information about tissues. Dual-energy/spectral CT systems. Dual-energy CT: material differentiation. Material specific

DECT data sets

Virtual unenhanced images

• Image data sets are equivalent to non-contrast CT images

• Eliminate the need for true unenhanced acquisition thereby

reducing radiation dose

Material specific iodine images

• Image data sets show distribution of iodine in tissues

independent of background attenuation

• Provide a reliable representation of tissue enhancement

• Improved detection of lesion enhancement compared to HU

measurements

Page 17: Dual energy CT - ZOL · 2020-02-27 · Dual-energy CT More information about tissues. Dual-energy/spectral CT systems. Dual-energy CT: material differentiation. Material specific

VNC images

Page 18: Dual energy CT - ZOL · 2020-02-27 · Dual-energy CT More information about tissues. Dual-energy/spectral CT systems. Dual-energy CT: material differentiation. Material specific

Material specific iodine

Page 19: Dual energy CT - ZOL · 2020-02-27 · Dual-energy CT More information about tissues. Dual-energy/spectral CT systems. Dual-energy CT: material differentiation. Material specific
Page 20: Dual energy CT - ZOL · 2020-02-27 · Dual-energy CT More information about tissues. Dual-energy/spectral CT systems. Dual-energy CT: material differentiation. Material specific
Page 21: Dual energy CT - ZOL · 2020-02-27 · Dual-energy CT More information about tissues. Dual-energy/spectral CT systems. Dual-energy CT: material differentiation. Material specific

All cakes and ale?

Dose?

Metal artifacts?

Size?

Exam time?

Transmission time?

Education?

Page 22: Dual energy CT - ZOL · 2020-02-27 · Dual-energy CT More information about tissues. Dual-energy/spectral CT systems. Dual-energy CT: material differentiation. Material specific

Dose

• The radiation exposure required for DECT depends on the

technology used (dual source < single source)

• The aim is to use the same dose as would be used for a

single-energy examination

• Less number of scan phases

• Elimination of true non-contrast with VNC: -20%

• Elimination of true non-contrast and arterial phase: -64%

Page 23: Dual energy CT - ZOL · 2020-02-27 · Dual-energy CT More information about tissues. Dual-energy/spectral CT systems. Dual-energy CT: material differentiation. Material specific

Examples

Page 24: Dual energy CT - ZOL · 2020-02-27 · Dual-energy CT More information about tissues. Dual-energy/spectral CT systems. Dual-energy CT: material differentiation. Material specific

Kidney stones

Page 25: Dual energy CT - ZOL · 2020-02-27 · Dual-energy CT More information about tissues. Dual-energy/spectral CT systems. Dual-energy CT: material differentiation. Material specific

Kidney stones

Page 26: Dual energy CT - ZOL · 2020-02-27 · Dual-energy CT More information about tissues. Dual-energy/spectral CT systems. Dual-energy CT: material differentiation. Material specific

Kidney stones

Page 27: Dual energy CT - ZOL · 2020-02-27 · Dual-energy CT More information about tissues. Dual-energy/spectral CT systems. Dual-energy CT: material differentiation. Material specific

Kidney stones

Page 28: Dual energy CT - ZOL · 2020-02-27 · Dual-energy CT More information about tissues. Dual-energy/spectral CT systems. Dual-energy CT: material differentiation. Material specific

Gout

Page 29: Dual energy CT - ZOL · 2020-02-27 · Dual-energy CT More information about tissues. Dual-energy/spectral CT systems. Dual-energy CT: material differentiation. Material specific

Gout

Page 30: Dual energy CT - ZOL · 2020-02-27 · Dual-energy CT More information about tissues. Dual-energy/spectral CT systems. Dual-energy CT: material differentiation. Material specific

Gout

• Calcium and urate: marked difference in photoelectric

absorption

o Sensitivity: 78-100%

o Specificity: 89-100%

• Can calculate tophi volume

Page 31: Dual energy CT - ZOL · 2020-02-27 · Dual-energy CT More information about tissues. Dual-energy/spectral CT systems. Dual-energy CT: material differentiation. Material specific

Gout

Page 32: Dual energy CT - ZOL · 2020-02-27 · Dual-energy CT More information about tissues. Dual-energy/spectral CT systems. Dual-energy CT: material differentiation. Material specific

Lung embolism

Page 33: Dual energy CT - ZOL · 2020-02-27 · Dual-energy CT More information about tissues. Dual-energy/spectral CT systems. Dual-energy CT: material differentiation. Material specific

Lung embolism

Page 34: Dual energy CT - ZOL · 2020-02-27 · Dual-energy CT More information about tissues. Dual-energy/spectral CT systems. Dual-energy CT: material differentiation. Material specific

Lung embolism

Page 35: Dual energy CT - ZOL · 2020-02-27 · Dual-energy CT More information about tissues. Dual-energy/spectral CT systems. Dual-energy CT: material differentiation. Material specific

Conclusion

Page 36: Dual energy CT - ZOL · 2020-02-27 · Dual-energy CT More information about tissues. Dual-energy/spectral CT systems. Dual-energy CT: material differentiation. Material specific

Real?

Page 37: Dual energy CT - ZOL · 2020-02-27 · Dual-energy CT More information about tissues. Dual-energy/spectral CT systems. Dual-energy CT: material differentiation. Material specific

Dank u voor uw aandacht