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    Echocardiography for the

    Surgeons

    Dr. Rezwanul Hoque BulbulMS, FCPS, FRCSG, FRCSEd

    Associate ProfessorBSM Medical University, Dhaka

    Bangladesh

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    General concepts

    The use of ultrasound toexamine the heart- a safe,powerful, non-invasive andpainless technique

    Sound is the disturbance

    propagating in a material Frequency is the

    oscillations per second

    Frequency higher than20KHz can not beperceived by ear- known as

    ultrasound Echo uses frequency range

    1.5MHz to 7.5 MHz, upto15MHz for skin lesion.

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    Basic concepts of US

    Velocity of sound- in heart 1540m/s, in air 330m/s

    Velocity divided by frequency gives wave length

    Shorter the wavelength, higher is the resolution,

    greater is the penetrationPiezoelectric crystals converts electricaloscillation to mechanical oscillation to produceUS, opposite occurs when same crystal acts as

    receiverThe repetition rate is 1000/s, transmission 1micro sec, remaining time spent in receivingmode

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    Probe-types for 2-D1.Mechanical sector scanner

    2.Phased array sector scanner

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    Machines

    There are 5 basic components of an ultrasound scanner that are

    required for generation, display and storage of an ultrasound

    image.1. Pulse generator - applies high amplitude voltage to energize the

    crystals

    2. Transducer - converts electrical energy to mechanical (ultrasound)energy and vice versa

    3. Receiver - detects and amplifies weak signals

    4. Display - displays ultrasound signals in a variety of modes

    5. Memory - stores video display

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    Viewing the Heart

    Windows allow good

    penetration by US withouttoo much masking by Lung

    or ribs

    Echo may be difficult in

    those with chest wall

    deformity, COPD, lungfibrosis, obese person

    Axis refers to the plane in

    which the US beam travels

    through the heart

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    Echo windows & views

    Left parasternal window( 2nd-4th ICS,

    left sternal edge)

    Long axis view,

    Short axis view(AV, MV,LV Papillary muscle,LV apex level)

    Apical window

    4 chamber ,5 chamber( aortic outflow) , Longaxis & 2 chamber view

    Subcostal window- useful in lung

    disease

    Supracostal window

    Right parasternal window

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    Parasternal Long-Axis View (PLAX)

    Transducer position: left sternaledge; 2nd 4th intercostal space

    Marker dot direction: pointstowards right shoulder

    Most echo studies begin with thisview

    It sets the stage for subsequentecho views

    Many structures seen from this

    view

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    Parasternal Short Axis View (PSAX)

    Transducer position: left sternal edge; 2nd

    4th intercostal space

    Marker dot direction: points towards leftshoulder(900 clockwise from PLAX view)

    By tilting transducer on an axis between theleft hip and right shoulder, short axis viewsare obtained at different levels, from theaorta to the LV apex.

    Many structures seen

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    Papillary Muscle (PM)level

    PSAX at the level of thepapillary muscles showinghow the respective LVsegments are identified,usually for the purposes ofdescribing abnormal LV wallmotion

    LV wall thickness can also be

    assessed

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    Apical 4-Chamber View (AP4CH)

    Transducer position: apex ofheart

    Marker dot direction: pointstowards left shoulder

    The AP5CH view is obtained fromthis view by slight anteriorangulation of the transducertowards the chest wall. The LVOTcan then be visualised

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    Apical 2-Chamber View (AP2CH)

    Transducer position: apex of the heart

    Marker dot direction: points towardsleft side of neck (450 anticlockwise

    from AP4CH view)

    Good for assessment of

    LV anterior wall

    LV inferior wall

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    Apical 5-chamber view

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    SubCostal 4 Chamber View(SC4CH)

    Transducer position: under thexiphisternum

    Marker dot position: points towards leftshoulder

    The subject lies supine with head slightly

    low (no pillow). With feet on the bed, theknees are slightly elevated

    Better images are obtained with theabdomen relaxed and during inspiration

    Interatrial septum, pericardial effusion,

    desc abdominal aorta

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    Suprasternal View

    Transducer position: suprasternal notch

    Marker dot direction: points towards left jaw

    The subject lies supine with the neckhyperextended. The head is rotated slightly

    towards the left

    The position of arms or legs and the phase ofrespiration have no bearing on this echowindow

    Arch of aorta

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    Echo Techniques

    2-D echo

    M-mode echo

    Pulsed wave Doppler

    Continuous wave Doppler

    Color flow mapping

    Stress echo

    3-D echo

    Preoperative

    Intraoperative

    Postoperative

    Transthoracic echo

    Trans oesophageal echo

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    Diastole/ Systole in echo

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    2-D echo

    Gives a snapshot in time of a cross-section of

    tissue

    Ultrasound is transmitted along several scan

    lines(90-120), over a wide arc(about 900) and

    many times per second.

    The combination of reflected ultrasound

    signals builds up an image on the displayscreen.

    This technique is used to "see" the actualstructures and motion of the heart structures atwork.

    Real-time imaging is possible if the scanningand display is rapid

    Sector imaging is possible either by

    mechanical rotation of a transducer or phasedelectric stimulation of array of crystals

    Anatomy, chamber size, intra & extra cardiacmass, fluid collection

    Ventricular and valvular movement

    A 2-D echo view appears cone-shaped on the

    monitor.

    Positioning for M-mode and Doppler echo

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    M-mode echo( 1-D echo)

    Motion mode echo is produced by

    transmission and reception of US along

    only one line

    An M- mode echocardiogram is not a

    "picture" of the heart, but rather a

    diagram that shows how the positions of

    its structures change during the course of

    the cardiac cycle.

    M-mode recordings permit measurement

    of cardiac dimensions and motion

    patterns.

    Also facilitate analysis of timerelationships with other physiological

    variables such as ECG, and heart

    sounds.

    More sensitive than 2-D echo in imaging

    moving object

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    Distance

    Systole

    M-mode at Mitral Valve

    Diastole

    Time

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    Systole

    M-mode at Mitral Valve

    Diastole

    dc

    a

    f

    e

    d

    Time

    Distance

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    Systole

    M-mode at Mitral Valve

    Diastole

    e

    d Time

    Distanced-e

    amplitude

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    Systole

    M-mode at Mitral Valve

    Diastole

    Septum

    e

    Time

    DistanceEPSS

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    Systole

    M-mode at Mitral Valve

    Diastole

    e

    d Time

    Distanced-e slope

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    Systole

    M-mode at Mitral Valve

    Diastole

    f

    e

    Time

    Distancee-f slope

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    M-mode at the Mitral Valve

    Amplitude DescriptionNormal

    Value

    EPSS Measure e point to septal

    separation

    < 5 mm

    d-e Measures the maximum

    excursion of the mitral valve

    following diastolic opening.

    17 to 30 mm

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    M-mode at the Mitral Valve

    Slope Description Normal Value

    d-e Measure rate of initialopening of the mitral valve

    in early diastole.

    240 to 380mm/s

    e-f Measures the rate of early

    closure of the mitral valve

    following diastolic opening.

    50 to 180 mm/s

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    Distance

    Systole

    M-mode at Mitral Valve

    Diastole

    Time

    Systolic anterior motionof the AMVL

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    Distance

    Systole

    M-mode at Mitral Valve

    Diastole

    Time

    MV prolapseposterior leaflet

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    M-mode at the Aortic Valve

    Coronarycusp

    Non-coronary cusp

    Anterior aortic root

    Posterior aortic root

    Left Atrium

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    M-mode at the Aortic Valve

    LA dimension

    Cusp SeparationAortic root

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    Assessment of Severity

    Maximal aortic cusp separation(MACS) on M-mode

    Vertical distance between RCC andNCC during systole

    Stenotic Aortic Valve decreasedMACS

    Limitations

    Single dimensionAsymmetrical AV involvement

    Calcification / thickness

    LV systolic function

    CO status

    AVA MACS

    N > 2cm2 N > 15 mm

    < 0.75 cm2 < 8 mm

    > 1 cm2 > 12 mm

    gray area 8 12 mm

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    M-mode at Left Ventricle

    LVPWd

    IVS

    RVIDd/RVIDs

    LVIDd/LVIDs

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    M-mode LV Calculation

    FS = LVIDd LVIDsLVIDd

    EF = LVIDd3 LVIDs3LVIDd3

    IVS % thickening = (IVSs IVSd) x 100IVSd

    LVPW % thickening = (LVPWs LVPWd) x 100LVPWd

    LV Mass = 1.04 {(LVIDd + IVSd + LVPWd)3 (LVIDd)3} x 0.8 + 0.6g

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    E-F slope

    The two mitral leafletsmove in diastole in M-

    shaped mirror image

    pattern. At the onset of

    systole the two leaflets

    come together sharply toproduce the 1st heart

    sound. The early diastolic

    velocity of the leaflets,

    called the E to F slope is

    dependent on the rate ofLV filling. The velocity may

    be slowed when the rate of

    filling is slowed( MS).

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    LV SYSTOLIC FUNCTION

    Quantitative echo

    LV VOLUME

    LV MASS

    EJECTION INDICES

    STROKE VOLUME

    EJECTION FRACTIONFRACTIONAL SHORTENING

    VELOCITY OF CIRCUMFERENCIAL FIBRE

    SHORTENING

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    Quantify LV function -MODES

    M-Mode

    Modified Simpsons Method Single plane area-length method

    Velocity of Circumferential Shortening

    Mitral Annular Excursion

    E-point to septal separation

    Rate of rise of MR jet

    Index of myocardial performance

    Subjective assessment

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    Fractional shortening

    Fractional shortening (FS) is the fraction of any diastolic dimension

    that is lost in systole. When referring to endocardial luminal

    distances, it is EDD minus ESD divided by EDD (times 100 when

    measured in percentage).

    Normal values may differ somewhat dependent on which

    anatomical plane is used to measure the distances, but a rangefrom 30 to 42% is considered normal with 26 to 30% representing a

    mild decrease in function.

    Midwall fractional shortening may also be used to measure

    diastolic/systolic changes for inter-ventricular septal dimensions and

    posterior wall dimensions. However, both endocardial and midwall

    fractional shortening are dependent on myocardial wall thickness,and thereby dependent on long-axis function.

    By comparison, a measure of short-axis function termed epicardial

    volume change (EVC) is independent of myocardial wall thickness

    and represents isolated short-axis function.

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    In cardiovascular physiology, ejection

    fraction (EF) represents the volumetric

    fraction of blood pumped out of the

    ventricle (heart) with each heart beat orcardiac cycle. It can be applied to either

    the right ventricle which ejects via the

    pulmonary valve into the pulmonary

    circulation or the left ventricle which

    ejects via the aortic valve into the

    systemic circulation. Ejection fraction

    (Ef) is the fraction of the end-diastolic

    volume that is ejected with each beat;that is, it is stroke volume (SV) divided

    by end-diastolic volume (EDV):Tests for measuringEF:

    Echocardiogram

    MUGA scan

    CAT scan

    Cardiac catheterization

    Nuclear stress test

    Measure Typical value Normal rangeend-diastolic volume (EDV)120 mL[1] 65240 mL

    end-systolic volume (ESV) 50 mL 16143 mL

    stroke volume (SV) 70 mL 55100 mL

    ejection fraction (Ef) 58% 5570%[2]

    heart rate (HR) 75 bpm 60100 bpm

    cardiac output (CO) 5.25 L/minute 4.08.0 L/min

    Depends on contractility, preload and

    afterload, heart rate, synchronicity ofcontractions

    Global parameter, regional differences incontractility averaged

    LV ejection fraction

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    LVEF

    Qualitative - visual

    inspection

    severity: mild, moderate,

    severe

    focality: global

    reported as a range in

    intervals of 5-10%

    regional: 17 segments

    Quantitative

    accuracy, reproducibility

    limited

    assumes shape of LV cavity

    best in symmetric ventricles

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    Simpsons Rule the biplane method

    of disks

    Volume left ventricle

    - manual tracings in systole and

    diastole

    - area divided into series of

    disks

    - volume of each disk ( r2 * h )

    summed = ventricular

    volume

    LV-ED LV-ES

    A4C

    A2C

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    Simpsons Rule the biplane

    method of disks

    Once volumes determined, EF is calculated :

    LV diastolic volume - LV systolic volume x 100%LV diastolic volume

    Normal > 50%, 35 to 50% moderately

    depressed,

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    LVEF-other echocardiographic

    method

    Echocardiographic methods included:1. Cubed M-mode formula

    2. Teichholz M-mode formula

    3. Subjective estimation of LVEF from two-dimensional

    videotape4. Area-length method in one four-chamber view

    5. Average of area-length method in three four-chamber

    views

    6. Average of area-length method in four-chamber and two-

    chamber views (one beat each)7. Subjective estimation from stored videoloop of four-

    chamber and two-chamber view

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    Diastolic Dysfunction

    Diastolic Dysfunction

    Equates to reversed E/A ratio(smaller E wave - taller Awave)

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    L f i l bi l l

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    Formulas andCalculationsBiplane volume & ejection fraction

    (Area/length 2D axes )Left ventricular mass, 2D

    Circumferential end-systolic wall stress

    Preload

    Left ventricular segmental wall motion

    Left atrial biplane volume

    Left atrial appendage shear rate of bloodLong / short axis ratio

    Mitral valve percent calcification

    Mitral score

    Left ventricular biplane volume(Area/length,Dodge correction)(area planimetry1 x area

    planimetry2 x 8) / (3 x xsmallest long axis) (ml)

    Transthoracic parasternal short axis viewA1 Red: tracing of pericardial borderA2 Green: tracing of endocardial border (papillarymuscles are excludedAm = A1 - A2 = area of myocardiumt: myocardial thickness (automatically calculated bythe software)LV mass index (truncated ellipsoid) normal values:Males: 7613 gm/m2Females: 6611 gm/m2

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    Valve area calculation

    1 Planimetry

    2 The continuity equation

    3 The Gorlin equation

    4 The Hakki equation5 Real-time three-

    dimensional

    echocardiography

    Gorlin Formula

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    The Doppler shift (Fd) of

    ultrasound will depend on

    both the transmitted

    frequency (fo) and thevelocity (V) of the moving

    blood. This returned

    frequency is also called the

    "frequency shift" or

    "Doppler shift" and is highlydependent on the angle of

    ultrasound beam from the

    transducer and the moving

    red blood cells. The

    velocity of sound in blood

    is constant (c)

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    Spectral analysis

    The difference in waveformbetween the transmitted andbackscattered signal iscompared.

    A process called fast Fouriertransform (FFT) displays this

    information into a spectralanalysis (spectral display ofentire range of velocities)

    Time- x axis

    Velocity- y axis

    Toward the transducer is

    positive, away from transducernegative.

    Amplitude is displayed asbrightness of the signal.

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    AliasingCorrected by:-

    Increasing the pulse repetitionfrequency(PRF)

    Decreasing the transmitted

    frequency

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    CW Doppler echo PW Doppler echo

    A single crystal is used for

    transmitting and receiving US Depth is measured by

    multiplying half of time delaywith velocity of sound in thetissue

    Can localize the site of flowdisturbance

    Detects normal valve flowpattern

    LV diastolic function

    Measurement of stroke volumeand cardiac output

    Can not measure velocity > 2m/s

    Two crystals- one

    transmitting anotherreceiving continuously are

    used

    Measures high velocity but

    can not localize depth and

    width precisely

    Detects severity of valvular

    stenosis, valvular

    regurgitation and velocity of

    flow in shunts

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    Color flow mapping

    2-D version of PW Doppler with color coding

    Velocity away from transducer is blue, towards

    it is red( BART), green applied to mosaic flow

    Higher velocity appears lighter, color reversaloccurs above a threshold velocity

    Used for assessment of shunt or regurgitation

    CW & PW Doppler allow graphical

    representation of velocity against time knownas spectral Doppler

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    Color Doppler

    Displayed as color information-Amplitude- intensity

    Direction- red vs. blue (toward or away from

    transducer)Velocity- brightness (bright blue higher velocity)

    Variance (turbulence)- coded green to give amosaic appearance.

    Overlays this information on 2D images

    Time consuming (temporal resolution isespecially poor with a large sector window)

    Different vendors have different algorithmsfor generating color Doppler

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    Tissue Doppler Imaging

    Routine Doppler targets blood flow High velocity

    Low signal amplitude

    Tissue Doppler (assessing the

    movement of the myocardium)

    targets tissue Low velocity

    High signal amplitude

    Different Filters

    Velocity of tissue along a particular

    sample volume

    Color-TDI, Velocity of tissue

    coded by color superimposed on

    2-D image . Can derive

    information such as strain, strain

    rate, dyssynchronyetc.

    Trans oesophageal echocardiography

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    This is an alternative way to perform an

    echocardiogram. A specialized probe

    containing an ultrasound transducer at its

    tip is passed into thepatient's oesophagus. This allows image

    and Doppler evaluation from a location

    directly behind the heart.

    Transesophageal echocardiograms are

    most often utilized when transthoracic

    images are suboptimal and when a more

    clear and precise image is needed for

    assessment.

    p g g p y

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    C li ti d t t d ith

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    Complications detected with

    Intraoperative TEE

    Intracardiac air

    Intracavitary

    Intercavitary

    Myocardial

    Individual targets

    Ventricular dysfunction

    Left ventricle

    Right ventricle

    Following valvular replacement Paravalvular regurgitation

    Outflow tract obstruction

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    Prosthetic Valve Pathology

    Prosthetic Valve Regurgitation

    Aortic Mitral

    Prosthetic Valve Stenosis

    Aortic

    Mitral

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    Bioprosthetic valves

    Mitral Position

    2-D ECHOCARDIOGRAPHIC APPEARANCE

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    Special Problems of 2-D Imaging

    Artificial Valves

    Echocardiographs are calibrated to measure distance based on the

    speed of sound in tissue.

    Prosthetic valves have different acoustic properties than tissue. Hence,

    distortion of:

    Size

    Location, and

    Appearance, of the prosthesis.

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    Indices of Valve Stenosis which

    are less flow dependent

    A. Contour of jet velocity

    B. Doppler velocity index

    C. Effective orifice area

    D. Valve resistance

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    A-Contour of the jet velocity

    With prosthetic obstructionthere is:

    Late peaking of the velocity,

    More rounded contour,

    Prolonged ejection.

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    Prosthetic Valve Regurgitation

    Physiologic Regurgitation

    Early onsetand brief duration

    Reflects backflow from closing movement of

    occluding device

    Tilting disc and bileaflet valves have additional late

    backflowleakage

    Intended to reduce risk of thrombosis

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    Mitral Prosthesis Regurgitation

    TTE of limited value in assess MR due to acoustic

    shadowing of the LA

    Doppler findings suggestive of severe MR

    E wave > 1.9 m.s

    PISA

    Short isovolumetic relaxation timeTVILVOT/TVIPr-MV < 0.4

    Normal values for adult

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    Normal values for adult

    LVIDs End systole 2.0-4.0 cm

    LVIDd End diastole 3.5-5.6 cm

    Wall thickness

    Diastolic Septum

    Post wall

    0.6-1.2 cm

    0.6-1.2 cm

    Systolic Septum

    Post wall

    0.9-1.8 cm

    0.9-1.8 cm

    FS 30-45%

    EF 50-85%

    LAD 2.0-4.0 cm

    Aortic root diameter 2.0-4.0 cm

    RV diameter 0.7-2.3 cm

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    Range MeanIVS wall thickness (cm) 0.6-1.1 0.9 0.4

    Aortic root dimension (cm) 2.0-3.5 2.4 0.4Aortic cusps separation (cm) 1.5-2.6 1.9 0.4Percentage of fractional

    shortening 34-44% 36%

    Mitral flow (m/s) 0.6-1.3 0.9Tricuspid flow (m/s) 0.3-0.7 0.5Pulmonary artery (m/s) 0.6-0.9 0.75

    Aorta (m/s) 1.0-1.7 1.35

    The Bernoulli equation is a

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    The Bernoulli equation is a

    complex formula that

    relates the pressure drop

    (or gradient) across anobstruction to many factors

    For practical use in

    Doppler echocardiography

    this formula has been

    simplified to:

    p1-p2=4V2

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    Echo-Doppler estimates of flow volume are based upon aknowledge of the area of flow (from echocardiogram) and thelength (from Doppler). It is assumed that the aorta is a cylinder.Doppler estimates of cardiac output compare quite favourably

    with those obtained by other methods.

    Pulmonary valve disease

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    Idealized spectralrecordings demonstratingthat time-to-peak velocity isvery rapid in patients withpulmonary hypertension.

    CW Doppler spectral velocity recordingof mild pulmonic stenosis and insufficiency.The abnormal diastolic flow toward thetransducer of pulmonic insufficiency iseasily recognized. (Scale marks = 1m/s)

    Flow towards the transducer gives positive waves, away from transducer negative deflection

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    Aortic stenosis

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    PW Doppler spectral recording ofaortic blood flow (arrow) takenfrom the apical window.

    Note the laminar appearance ofnormal flow. (Scale marks = 20cm/s)

    CW spectral recording from theapex in a patient with aorticstenosis. The velocity spectrumis broadened and systolicvelocity is increased to 4 m/s.

    (Scale marks = 2 m/s)

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    The duration of mitral insufficiency is

    ll l th th t f

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    Aortic stenosis (left) should not bemistaken for mitral insufficiency(right). Mitral systole begins beforeaortic (arrow) and is longer induration. (Scale marks = 2m/s)

    generally longer than that of

    aortic stenosis, partly because the

    time from mitral valve closing to

    opening is longer than for aorticvalve opening to closing. Similarly,

    the duration of aortic insufficiency is

    longer than mitral stenosis because

    the time from aortic valve closing to

    opening is longer than for mitral

    valve opening to closing. Similarrelationships are true of the pulmonic

    and tricuspid valve on the right side

    of the heart.

    Left panel shows an aortic stenotic jetin relation to possible viewingdirections using CW Doppler. Rightpanel shows spectral velocity tracingsfrom each respective window. The bestrecording is from the right sternal

    window. (Calibration marks = 2m/s)

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    The severity of aortic stenosis may also be

    judged by the relative proportion of totalsystolic time taken to reach peak velocity(stippled areas). Both time to peak and peakvelocity are lower in panel A than in panel B.((Scale marks = 1m/s)

    Continuity of forward flow. Flow thatenters a cylinder is equal to the flowpassing through an obstruction andexiting from the distal side.

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    Tricuspid stenosisPulmonary stenosis

    Coarctation of Aorta HOCM

    VSD

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