editorial comment

1
cumstances, such as a cluster of cases in a family or commu- nity, or complicated cases. CONCLUSIONS Our results indicate that epididymitis in boys is not a rare illness. Clinical and laboratory finding suggest an inflamma- tory phenomenon (presumably post-infectious) with a benign course. The treatment of these patients is basically with analgesics and nonsteroidal anti-inflammatory drugs with a little role for antibiotics. However, it should be emphasized that ruling out testicular torsion is the most important step in the evaluation of the patient with epididymitis. REFERENCES 1. Bukowski, T. P., Lewis, A. G., Reeves, D., Wacksman, J. and Sheldon, C. A.: Epididymitis in older boys: dysfunctional void- ing as an etiology. J Urol, 154: 762, 1995 2. Richman, M. N. and Bukowski, T. P.: Pediatric epididymitis: pathophysiology, diagnosis and management. Infect Urol, 14: 31, 2001 3. Cappele, O., Liard, A., Barret, E., Bachy, B. and Mitrofanoff, P.: Epididymitis in children: is further investigation necessary after the first episode? Eur Urol, 38: 627, 2000 4. Merlini, E., Rotundi, F., Seymandi, P. L. and Canning, D. A.: Acute epididymitis and urinary tract anomalies in children. Scand J Urol Nephrol, 32: 273, 1998 5. Lau, P., Anderson, P. A., Giacomantonio, J. M. and Schwarz, R. D.: Acute epididymitis in boys: are antibiotics indicated? Br J Urol, 79: 797, 1997 6. Gislason, T., Noronha, R. F. X. and Gregory, J. G.: Acute epidid- ymitis in boys: a 5-year retrospective study. J Urol, 124: 533, 1980 7. Lewis, A. G., Bukowski, T. P., Jarvis, P. D., Wacksman, J. and Sheldon, C. A.: Evaluation of acute scrotum in the emergency department. J Pediatr Surg, 30: 277, 1995 8. Klin, B., Zlotkevich, L., Horne, T., Efrati, Y., Serour, F. and Lotan, G.: Epididymitis in childhood: a clinical retrospective study over 5 years. Isr Med Assoc J, 3: 833, 2001 9. Elder, J. S.: Urologic disorders in infants and children. Disorders and anomalies of the scrotal contents. In: Nelson Textbook of Pediatrics, 16th ed. Edited by R. E. Behrman, R. M. Kliegman and H. B. Jenson. Phiadelphia: W. B. Saunders Co., pp. 1652– 1653, 2000 10. Sidler, D., Brown, R. A., Millar, A. J., Rode, H. and Cywes, S.: A 25-year review of the acute scrotum in children. S Afr Med J, 87: 1696, 1997 11. Hutcheson, J., Peters, C. A. and Diamond, D. A.: Amiodarone induced epididymitis in children. J Urol, 160: 515, 1998 12. Cassidy, T. S. and Petty, R. E.: Arthritis related to infection. In: Textbook of Pediatric Rheumatology, 3rd ed. Edited by T. S. Cassidy and R. E. Petty. Philadelphia: W. B. Saunders Co., pp. 487–530, 1995 13. Morag, A. and Ogra, P. L.: Enteroviruses. In: Nelson Textbook of Pediatrics, 16th ed. Edited by R. E. Behrman, R. M. Kliegman and H. B. Jenson. Philadelphia: W. B. Saunders Co., pp. 956 – 964, 2000 EDITORIAL COMMENT The authors reported novel and intriguing information regarding elevated viral titers in prepubertal boys presenting with acute scro- tal swelling and pain who were thought to have acute epididymitis. The diagnosis of acute epididymitis was based on physical findings and sonographic evidence of a congested epididymitis with increased blood flow. Using these criteria 71% of the patients presenting to their emergency department with acute scrotal swelling were as- signed this diagnosis. Although this article raises interesting questions regarding the etiology of acute epididymitis, one must recognize the limited ability of sonography to differentiate acute epididymitis from torsion of the appendix testis. The 2 conditions can cause congestion of the epidid- ymal tissue with increased blood flow, tenderness and scrotal swell- ing secondary to the inflammatory response. At our institution tor- sion of the appendix testis is thought to occur much more commonly than acute epididymitis in the prepubertal male and yet the authors apparently made this diagnosis in only a small minority of their patients (11%, presumably the 7 with sonographic evidence of in- creased blood flow without epididymal enlargement). Furthermore, of the 44 patients diagnosed with acute epididymitis only a small minority (16%) had fever. Urinalysis was normal in almost all cases and the mean serum white blood count in this group was normal. All of these findings call into question the accuracy of the diagnosis of acute epididymitis in many of these patients. However, we would agree with the author recommendations that antibiotic therapy is unnecessary. In fact, almost all of these boys can be treated as outpatients with ibuprofen and limited activity restriction. H. Gil Rushton Division of Pediatric Urology Children’s National Medical Center Urology and Pediatrics George Washington University School of Medicine Washington, D. C. ACUTE EPIDIDYMITIS IN CHILDREN 394

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cumstances, such as a cluster of cases in a family or commu-nity, or complicated cases.

CONCLUSIONS

Our results indicate that epididymitis in boys is not a rareillness. Clinical and laboratory finding suggest an inflamma-tory phenomenon (presumably post-infectious) with a benigncourse. The treatment of these patients is basically withanalgesics and nonsteroidal anti-inflammatory drugs with alittle role for antibiotics. However, it should be emphasizedthat ruling out testicular torsion is the most important stepin the evaluation of the patient with epididymitis.

REFERENCES

1. Bukowski, T. P., Lewis, A. G., Reeves, D., Wacksman, J. andSheldon, C. A.: Epididymitis in older boys: dysfunctional void-ing as an etiology. J Urol, 154: 762, 1995

2. Richman, M. N. and Bukowski, T. P.: Pediatric epididymitis:pathophysiology, diagnosis and management. Infect Urol, 14:31, 2001

3. Cappele, O., Liard, A., Barret, E., Bachy, B. and Mitrofanoff, P.:Epididymitis in children: is further investigation necessaryafter the first episode? Eur Urol, 38: 627, 2000

4. Merlini, E., Rotundi, F., Seymandi, P. L. and Canning, D. A.:Acute epididymitis and urinary tract anomalies in children.Scand J Urol Nephrol, 32: 273, 1998

5. Lau, P., Anderson, P. A., Giacomantonio, J. M. and Schwarz,R. D.: Acute epididymitis in boys: are antibiotics indicated?Br J Urol, 79: 797, 1997

6. Gislason, T., Noronha, R. F. X. and Gregory, J. G.: Acute epidid-ymitis in boys: a 5-year retrospective study. J Urol, 124: 533,1980

7. Lewis, A. G., Bukowski, T. P., Jarvis, P. D., Wacksman, J. andSheldon, C. A.: Evaluation of acute scrotum in the emergencydepartment. J Pediatr Surg, 30: 277, 1995

8. Klin, B., Zlotkevich, L., Horne, T., Efrati, Y., Serour, F. andLotan, G.: Epididymitis in childhood: a clinical retrospectivestudy over 5 years. Isr Med Assoc J, 3: 833, 2001

9. Elder, J. S.: Urologic disorders in infants and children. Disordersand anomalies of the scrotal contents. In: Nelson Textbook ofPediatrics, 16th ed. Edited by R. E. Behrman, R. M. Kliegmanand H. B. Jenson. Phiadelphia: W. B. Saunders Co., pp. 1652–1653, 2000

10. Sidler, D., Brown, R. A., Millar, A. J., Rode, H. and Cywes, S.: A25-year review of the acute scrotum in children. S Afr Med J,

87: 1696, 199711. Hutcheson, J., Peters, C. A. and Diamond, D. A.: Amiodarone

induced epididymitis in children. J Urol, 160: 515, 199812. Cassidy, T. S. and Petty, R. E.: Arthritis related to infection. In:

Textbook of Pediatric Rheumatology, 3rd ed. Edited by T. S.Cassidy and R. E. Petty. Philadelphia: W. B. Saunders Co., pp.487–530, 1995

13. Morag, A. and Ogra, P. L.: Enteroviruses. In: Nelson Textbook ofPediatrics, 16th ed. Edited by R. E. Behrman, R. M. Kliegmanand H. B. Jenson. Philadelphia: W. B. Saunders Co., pp. 956–964, 2000

EDITORIAL COMMENT

The authors reported novel and intriguing information regardingelevated viral titers in prepubertal boys presenting with acute scro-tal swelling and pain who were thought to have acute epididymitis.The diagnosis of acute epididymitis was based on physical findingsand sonographic evidence of a congested epididymitis with increasedblood flow. Using these criteria 71% of the patients presenting totheir emergency department with acute scrotal swelling were as-signed this diagnosis.

Although this article raises interesting questions regarding theetiology of acute epididymitis, one must recognize the limited abilityof sonography to differentiate acute epididymitis from torsion of theappendix testis. The 2 conditions can cause congestion of the epidid-ymal tissue with increased blood flow, tenderness and scrotal swell-ing secondary to the inflammatory response. At our institution tor-sion of the appendix testis is thought to occur much more commonlythan acute epididymitis in the prepubertal male and yet the authorsapparently made this diagnosis in only a small minority of theirpatients (11%, presumably the 7 with sonographic evidence of in-creased blood flow without epididymal enlargement). Furthermore,of the 44 patients diagnosed with acute epididymitis only a smallminority (16%) had fever. Urinalysis was normal in almost all casesand the mean serum white blood count in this group was normal. Allof these findings call into question the accuracy of the diagnosis ofacute epididymitis in many of these patients. However, we wouldagree with the author recommendations that antibiotic therapy isunnecessary. In fact, almost all of these boys can be treated asoutpatients with ibuprofen and limited activity restriction.

H. Gil RushtonDivision of Pediatric UrologyChildren’s National Medical CenterUrology and PediatricsGeorge Washington University School of MedicineWashington, D. C.

ACUTE EPIDIDYMITIS IN CHILDREN394