electrical impedance tomography system ... - ventilation

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ELECTRICAL IMPEDANCE TOMOGRAPHY SYSTEM UTILIZATION FOR DIAGNOSTICS OF NEONATAL LUNGS Motivation: Clinical requirements for non-invasive, radiation free and bedside monitoring technique for neonatal intensive-care units (NICU), useful for monitoring of neonatal lungs function and condition and quantitative analysis of bronchopulmonary dysplasia. Aim: Utilization of electrical impedance tomography (EIT) system Maltron Sheffield MK 3.5 for measuring tidal volumes, lung density and other parameters depending on changes of electrical resistivity of the lung tissue with frequency (Fig. 1 left). The main goal is monitoring of electrical resistivity of the lungs in patients with bronchopulmonary dysplasia (BPD). Methods: This work is focused on neonatal patients with lung dysfunctions because a complex method for lung monitoring is needed. EIT system Maltron Sheffield MK 3.5 is used for monitoring of mechanical ventilation, in our case mostly continuous positive airway pressure (CPAP). Monitoring of selective high frequency jet ventilation was performed using EIT system. The electrical resistivity will be collated with a standard BPD classification and ventilation-to- perfusion ratio as well. Monitoring of tidal volumes and lung density (Fig. 1 right) is also possible. The main limitation of EIT system is data acquisition principle and complicated results interpretation requiring an erudite clinicians and biomedical engineers collaborating. Fig. 1 – Electrical resistivity changes with different frequency of applied current (left), total and regional lung density measured by EIT system Maltron Sheffield MK 3.5 (right). Conclusion: EIT system could be used for monitoring of maturational changes in neonatal lungs. Monitoring of mechanical ventilation is possible. It is necessary to verify the possibility of monitoring of BPD in a combination with measuring of a reduced VQ shunt. This material has been downloaded from www.ventilation.cz the site of Non-Conventional Ventilatory Team of the Czech Republic. The site contains the full-text versions of the cited articles and other materials dealing with artificial ventilation, especially high frequency ventilation (HFV, HFOV, HFJV) and other techniques of unconventional lung ventilation.

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Page 1: ELECTRICAL IMPEDANCE TOMOGRAPHY SYSTEM ... - Ventilation

ELECTRICAL IMPEDANCE TOMOGRAPHY SYSTEM UTILIZATION FOR DIAGNOSTICS OF NEONATAL LUNGS

Motivation:

Clinical requirements for non-invasive, radiation free and bedside monitoring technique for neonatal intensive-care units (NICU), useful for monitoring of neonatal lungs function and condition and quantitative analysis of bronchopulmonary dysplasia.

Aim:

Utilization of electrical impedance tomography (EIT) system Maltron Sheffield MK 3.5 for measuring tidal volumes, lung density and other parameters depending on changes of electrical resistivity of the lung tissue with frequency (Fig. 1 left). The main goal is monitoring of electrical resistivity of the lungs in patients with bronchopulmonary dysplasia (BPD).

Methods:

This work is focused on neonatal patients with lung dysfunctions because a complex method for lung monitoring is needed. EIT system Maltron Sheffield MK 3.5 is used for monitoring of mechanical ventilation, in our case mostly continuous positive airway pressure (CPAP). Monitoring of selective high frequency jet ventilation was performed using EIT system. The electrical resistivity will be collated with a standard BPD classification and ventilation-to-perfusion ratio as well. Monitoring of tidal volumes and lung density (Fig. 1 right) is also possible. The main limitation of EIT system is data acquisition principle and complicated results interpretation requiring an erudite clinicians and biomedical engineers collaborating.

Motivation: Clinical requirements for non-invasive, radiation free and bed-side monitoring technique for neonatal intensive-care units (NICU), useful for monitoring of neonatal lungs function and condition and quantitative analysis of bronchopulmonary dysplasia.

ELECTRICAL IMPEDANCE TOMOGRAPHY SYSTEM UTILIZATION FOR DIAGNOSTICS OF NEONATAL LUNGS

Methods: This work is focused on neonatal patients with lung dysfunctions because a complex method for lung monitoring is needed. There is possible to use EIT for monitoring of mechanical ventilation. Monitoring of tidal volumes and lung density (Fig. 2.) is also possible. There is necessary to standardize measuring conditions to exclude interindividual variations between the patients. The main limitation of EIT system is data acquisition principle and complicated results interpretation required an erudite clinicians and biomedical engineers collaborating. Results: EIT system Maltron Sheffield MK 3.5 is used for monitoring of mechanical ventilation (CPAP). Monitoring of selective high frequency jet ventilation was performed using EIT system. The main goal of the work is monitoring of electrical resistivity of the lungs on patients with bronchopulmonary dysplasia (BPD). The electrical resistivity will be collated with a standard BPD classification and ventilation to perfusion ratio as well. Conclusion: EIT system could be used for monitoring of maturational changes in neonatal lungs. Monitoring of mechanical ventilation is possible. There is necessary to verify the possibility of monitoring of BPD in a combination with measuring of a reduced VQ shunt.

Affilations: Study has been supported by MSM6840770012, GAČR 102/08/H018, SGS10/110/OHK4/1T/17 and SGS11/171/OHK4/3T/17.

Fig. 3: Electrical resistivity changes during one breath measured by Maltron Sheffield MK 3.5 EIT system

Fig. 1: Electrical resistivity changes during depends on a frequency of applied current

Publications: Suchomel, J., Kudrna, P. Electrical impedance tomography system on neonatal intensive care unit. Poster 2010 - Proceedings of the 14th International Conference on Electrical Engineering [CD-ROM]. Praha: ČVUT v Praze, FEL, 2010, ISBN 978-80-01-04544-2.

Aim: Utilization of Electrical Impedance Tomography (EIT) system Maltron Sheffield MK 3.5 for non-invasive measuring of tidal volumes, density of lungs and other parameters depending on changes of electrical resistivity of the lung tissue with frequency (Fig. 1.).

Fig. 2: Total and regional lung density measured by EIT system.

This material has been downloaded from www.ventilation.cz the site of Non-Conventional Ventilatory Team of the Czech Republic. The site contains the full-text versions of the cited articles and other materials dealing with artificial ventilation, especially high frequency ventilation (HFV, HFOV, HFJV) and other techniques of unconventional lung ventilation.

Motivation: Clinical requirements for non-invasive, radiation free and bed-side monitoring technique for neonatal intensive-care units (NICU), useful for monitoring of neonatal lungs function and condition and quantitative analysis of bronchopulmonary dysplasia.

ELECTRICAL IMPEDANCE TOMOGRAPHY SYSTEM UTILIZATION FOR DIAGNOSTICS OF NEONATAL LUNGS

Methods: This work is focused on neonatal patients with lung dysfunctions because a complex method for lung monitoring is needed. There is possible to use EIT for monitoring of mechanical ventilation. Monitoring of tidal volumes and lung density (Fig. 2.) is also possible. There is necessary to standardize measuring conditions to exclude interindividual variations between the patients. The main limitation of EIT system is data acquisition principle and complicated results interpretation required an erudite clinicians and biomedical engineers collaborating. Results: EIT system Maltron Sheffield MK 3.5 is used for monitoring of mechanical ventilation (CPAP). Monitoring of selective high frequency jet ventilation was performed using EIT system. The main goal of the work is monitoring of electrical resistivity of the lungs on patients with bronchopulmonary dysplasia (BPD). The electrical resistivity will be collated with a standard BPD classification and ventilation to perfusion ratio as well. Conclusion: EIT system could be used for monitoring of maturational changes in neonatal lungs. Monitoring of mechanical ventilation is possible. There is necessary to verify the possibility of monitoring of BPD in a combination with measuring of a reduced VQ shunt.

Affilations: Study has been supported by MSM6840770012, GAČR 102/08/H018, SGS10/110/OHK4/1T/17 and SGS11/171/OHK4/3T/17.

Fig. 3: Electrical resistivity changes during one breath measured by Maltron Sheffield MK 3.5 EIT system

Fig. 1: Electrical resistivity changes during depends on a frequency of applied current

Publications: Suchomel, J., Kudrna, P. Electrical impedance tomography system on neonatal intensive care unit. Poster 2010 - Proceedings of the 14th International Conference on Electrical Engineering [CD-ROM]. Praha: ČVUT v Praze, FEL, 2010, ISBN 978-80-01-04544-2.

Aim: Utilization of Electrical Impedance Tomography (EIT) system Maltron Sheffield MK 3.5 for non-invasive measuring of tidal volumes, density of lungs and other parameters depending on changes of electrical resistivity of the lung tissue with frequency (Fig. 1.).

Fig. 2: Total and regional lung density measured by EIT system.

This material has been downloaded from www.ventilation.cz the site of Non-Conventional Ventilatory Team of the Czech Republic. The site contains the full-text versions of the cited articles and other materials dealing with artificial ventilation, especially high frequency ventilation (HFV, HFOV, HFJV) and other techniques of unconventional lung ventilation.

Fig. 1 – Electrical resistivity changes with different frequency of applied current (left), total and regional lung density measured by EIT system Maltron Sheffield MK 3.5 (right).

Conclusion:

EIT system could be used for monitoring of maturational changes in neonatal lungs. Monitoring of mechanical ventilation is possible. It is necessary to verify the possibility of monitoring of BPD in a combination with measuring of a reduced VQ shunt.

This material has been downloaded from www.ventilation.cz the site of Non-Conventional Ventilatory Team of the Czech Republic. The site contains the full-text versions of the cited articles and other materials dealing with artificial ventilation, especially high frequency ventilation (HFV, HFOV, HFJV) and other techniques of unconventional lung ventilation.