ethics and resources in animal-based research. division of comparative medicine dr. kate banks msb...
TRANSCRIPT
![Page 1: Ethics and Resources in Animal-Based Research. Division of Comparative Medicine Dr. Kate Banks MSB 1236 k.banks@utoronto.ca (416) 978-6539](https://reader036.vdocuments.net/reader036/viewer/2022080914/56649f3e5503460f94c5f70c/html5/thumbnails/1.jpg)
Ethics and Resources in Animal-Based Research
![Page 3: Ethics and Resources in Animal-Based Research. Division of Comparative Medicine Dr. Kate Banks MSB 1236 k.banks@utoronto.ca (416) 978-6539](https://reader036.vdocuments.net/reader036/viewer/2022080914/56649f3e5503460f94c5f70c/html5/thumbnails/3.jpg)
Ethical Imperative
•Sentience, or capacity to perceive stimuli•Capacity to perceive painful stimuli•Responsibilities incurred
![Page 4: Ethics and Resources in Animal-Based Research. Division of Comparative Medicine Dr. Kate Banks MSB 1236 k.banks@utoronto.ca (416) 978-6539](https://reader036.vdocuments.net/reader036/viewer/2022080914/56649f3e5503460f94c5f70c/html5/thumbnails/4.jpg)
Provincial Law
•Animals for Research Act•Requirement for ethical review, training•Provisions for adequate and appropriate anesthesia and analgesia
Animals for Research Act, R.S.O. 1990, c. A.22
![Page 5: Ethics and Resources in Animal-Based Research. Division of Comparative Medicine Dr. Kate Banks MSB 1236 k.banks@utoronto.ca (416) 978-6539](https://reader036.vdocuments.net/reader036/viewer/2022080914/56649f3e5503460f94c5f70c/html5/thumbnails/5.jpg)
Canadian Council on Animal Care
•Guidelines on animal care •Not federally legislated•GAP certificates•Non-compliance
www.ccac.ca
![Page 6: Ethics and Resources in Animal-Based Research. Division of Comparative Medicine Dr. Kate Banks MSB 1236 k.banks@utoronto.ca (416) 978-6539](https://reader036.vdocuments.net/reader036/viewer/2022080914/56649f3e5503460f94c5f70c/html5/thumbnails/6.jpg)
Funding of Research
![Page 7: Ethics and Resources in Animal-Based Research. Division of Comparative Medicine Dr. Kate Banks MSB 1236 k.banks@utoronto.ca (416) 978-6539](https://reader036.vdocuments.net/reader036/viewer/2022080914/56649f3e5503460f94c5f70c/html5/thumbnails/7.jpg)
CIHR and the CCAC
The Agencies require that:• All the research they fund that involves the use of animals
be approved, in accordance with animal care standards, by the Researcher’s Institution before the work begins.
Policy and Legislation in the event of non-compliance:• Suspension of funding will last until the CCAC reports that
the Institution has initiated the actions required to bring it into compliance.
![Page 8: Ethics and Resources in Animal-Based Research. Division of Comparative Medicine Dr. Kate Banks MSB 1236 k.banks@utoronto.ca (416) 978-6539](https://reader036.vdocuments.net/reader036/viewer/2022080914/56649f3e5503460f94c5f70c/html5/thumbnails/8.jpg)
UofT Policy
•Standard of care to meet or exceed CCAC guidelines•Responsibility to comply with conditions set by CIHR, other public funding agencies•Delegates authority on all matters pertaining to ethics review to ACCs
![Page 9: Ethics and Resources in Animal-Based Research. Division of Comparative Medicine Dr. Kate Banks MSB 1236 k.banks@utoronto.ca (416) 978-6539](https://reader036.vdocuments.net/reader036/viewer/2022080914/56649f3e5503460f94c5f70c/html5/thumbnails/9.jpg)
Animal Care Committees
•Interpret regulatory guidelines other published sources, professional experience •Empowered by UofT, CCAC, Provincial law•Composed of your supervisor’s peers, veterinarians, veterinary technical staff, community representative
![Page 10: Ethics and Resources in Animal-Based Research. Division of Comparative Medicine Dr. Kate Banks MSB 1236 k.banks@utoronto.ca (416) 978-6539](https://reader036.vdocuments.net/reader036/viewer/2022080914/56649f3e5503460f94c5f70c/html5/thumbnails/10.jpg)
CCAC
Supervisor’s Animal Use
Protocol
Supervisor’s Animal Use
Protocol
Animal Care Committee Animals for
Research Act
![Page 11: Ethics and Resources in Animal-Based Research. Division of Comparative Medicine Dr. Kate Banks MSB 1236 k.banks@utoronto.ca (416) 978-6539](https://reader036.vdocuments.net/reader036/viewer/2022080914/56649f3e5503460f94c5f70c/html5/thumbnails/11.jpg)
Office of Research Ethics
• Administration of protocols following review and approval
• Explanation of review process• Animal Use Protocol, amendment forms• Instructions for completing forms
http://www.research.utoronto.ca/ethics/
![Page 12: Ethics and Resources in Animal-Based Research. Division of Comparative Medicine Dr. Kate Banks MSB 1236 k.banks@utoronto.ca (416) 978-6539](https://reader036.vdocuments.net/reader036/viewer/2022080914/56649f3e5503460f94c5f70c/html5/thumbnails/12.jpg)
Animal Use Protocol• The Faculty of Medicine and Pharmacy Animal Care Committee is
the committee responsible for reviewing and approving protocols
• FMPACC meets the first Wednesday of each month
• The signed protocol should be delivered to the DCM office (MSB1236) by 4:30 p.m. on the Wednesday preceding the scheduled meeting
• An electronic copy of the protocol must also be submitted to [email protected]
• It may take 4-6 weeks for the protocol to be processed
www.medresearch.utoronto.ca/dcm_home.html
![Page 13: Ethics and Resources in Animal-Based Research. Division of Comparative Medicine Dr. Kate Banks MSB 1236 k.banks@utoronto.ca (416) 978-6539](https://reader036.vdocuments.net/reader036/viewer/2022080914/56649f3e5503460f94c5f70c/html5/thumbnails/13.jpg)
Resources
• Training (basic & specialized)• DCM staff (protocol review, animal health & welfare,
husbandry, administrative, procedural, technical, animal models, experimental design)
• Office of Research Ethics• Refinement databases (NC3rs, CCAC, AHWLA)• Literature reviews